keyword
https://read.qxmd.com/read/38530546/impact-of-left-ventricular-hypertrophy-on-frequency-and-complexity-of-ventricular-arrhythmia-among-hypertensive-egyptian-patients
#1
JOURNAL ARTICLE
Ahmed Mokhtar Abd El Azeem, Mohamed Ahmed Abd Elmoneim, Samir Morkos Rafla, Gehan Magdy Youssif
BACKGROUND: Left ventricular hypertrophy (LVH) is associated with an increased risk of ventricular arrhythmias and cardiovascular mortality. The study objective was to investigate the effect of LVH severity on the complexity and severity of ventricular arrhythmias among a subset of Egyptian hypertensive patients. RESULTS: The study cohort consisted of 60 hypertensive patients with LVH as diagnosed by echocardiography. Their mean age was (53.7 ± 12...
March 26, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38509891/effect-of-the-civil-law-severability-doctrine-on-administrative-contract-theory-a-study-of-french-and-egyptian-laws
#2
REVIEW
Magdi Shouaib, Ahmed Eldakak, Eman Ahmed Alabdouli
This article investigates the application of the civil law severability doctrine in administrative law through an in-depth analysis of the French and Egyptian legal systems. Recognising the increasing complexity of administrative contracts and disputes, this study explores how administrative judges integrate the severability doctrine of civil law into their judgements. Specifically, it investigates whether and how this integration occurs and the balance that judges maintain between adhering to administrative law's independence and applying civil law principles...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38494252/assessment-of-vitamin-d-status-and-vitamin-d-receptor-polymorphism-in-egyptian-children-with-type-1-diabetes
#3
JOURNAL ARTICLE
Eman A Mostafa, Maha M A Abo Hashish, Nagwa Abdallah Ismail, Hasanin M Hasanin, Rasha M Hasanin, Aliaa Ahmed Wahby, Ingy Ashmawy, Shereen Hamdy Abd El Aziz, Mai Magdy Abdel Wahed
BACKGROUND: The endocrine system of vitamin D regulates about 3 % of the human genome. Vitamin D exerts its actions via a nuclear vitamin D receptor (VDR) which in turn regulates insulin secretion from the pancreas. VDR gene polymorphisms could have an impact on how autoimmune illnesses like Type 1 diabetes mellitus (T1DM) develop. We aimed to explore the relation between T1DM and VDR gene polymorphisms in Egyptian diabetic children and their siblings. METHODS: Enzyme-linked immunosorbent assay was used to quantify 25(OH) vitamin D in the study, which had 179 participants (group 1 = 85 diabetic children, group 2 = 57 siblings of the patients, group 3 = 37 healthy controls)...
March 2024: Journal, Genetic Engineering & Biotechnology
https://read.qxmd.com/read/38463260/utility-of-2-chloro-n-arylacetamide-and-1-1-piperazine-1-4-diyl-bis-2-chloroethanone-as-versatile-precursors-for-novel-mono-and-bis-thienopyridines
#4
JOURNAL ARTICLE
Mostafa E Salem, Abbas H Abdullah, Magdi E A Zaki, Ismail A Abdelhamid, Ahmed H M Elwahy
A series of novel thieno[2,3- b ]pyridines linked to N -aryl carboxamides or (carbonylphenoxy)- N -(aryl)acetamides, as well as bis(thieno[2,3- b ]pyridines) linked to piperazine core via methanone or carbonylphenoxyethanone units, were synthesized by treating the appropriate chloroacetyl- or bis-bromoacetyl derivatives with 2-mercaptonicotinonitrile derivatives in ethanolic sodium ethoxide at reflux. The spectral data were used to determine the compositions of novel compounds.
March 5, 2024: ACS Omega
https://read.qxmd.com/read/38452516/public-misconceptions-and-attitudes-towards-persons-diagnosed-with-epilepsy-in-the-kingdom-of-bahrain-a-cross-sectional-study
#5
JOURNAL ARTICLE
Alaa Elmazny, Mohammed Ahmed A Alkharisi, Yazed Saad J Ibrahim, Atheer Baalqasim A Albarakati, Shatha Shayan Almutairi, Lina Abdulrahim Altalhi, Enas Mostafa Darwish, Rehab Magdy, Eman Hany Elsebaie, Ahmed Dahshan
BACKGROUND: Despite significant advancements in the understanding and treatment of epilepsy, the quality of life for persons diagnosed with Epilepsy (PdwE) can still be negatively impacted due to prevalent misconceptions and societal attitudes. This study aimed to investigate the knowledge, misconceptions, and attitudes towards epilepsy in Bahrain. METHODS: This cross-sectional study involved 1079 participants aged ≥ 18 years living in Bahrain...
March 6, 2024: Epilepsy & Behavior: E&B
https://read.qxmd.com/read/38450853/quantifying-the-association-of-sperm-dna-fragmentation-with-assisted-reproductive-technology-outcomes-an-umbrella-review
#6
REVIEW
Hassan Maghraby, Mohamad AlaaEldein Elsuity, Nehal Adel, Yasmin Magdi, Amr S Abdelbadie, Mosab M Rashwan, Ola Youssef Ahmed, Mohamed Elmahdy, Khalid S Khan, Mohamed Fawzy
BACKGROUND: Systematic reviews and meta-analyses are instrumental in shaping clinical practice. However, their findings can sometimes be marred by discrepancies and potential biases, thereby diluting the strength of the evidence presented. Umbrella reviews serve to comprehensively assess and synthesise these reviews, offering a clearer insight into the quality of the evidence presented. In the context of the relationship between sperm DNA fragmentation (SDF) and assisted conception outcomes, there is a divergence in the literature...
March 7, 2024: BJOG: An International Journal of Obstetrics and Gynaecology
https://read.qxmd.com/read/38441828/value-of-different-cto-scoring-systems-in-predicting-procedural-success-in-coronary-chronic-total-occlusion-intervention-in-egyptian-patients
#7
JOURNAL ARTICLE
Ahmed Mohammed Ali AlAshry, Muhammed Nagy Nagiub, Magdy Farouk Ahmed Ismael, Wesam Alghonaimy
BACKGROUND: Chronic total occlusion (CTO) lesions in coronary arteries pose a significant challenge for coronary interventionists, often leading to referrals for coronary artery bypass graft surgery (CABG). Successful percutaneous coronary intervention (PCI) for CTOs requires accurate assessment of procedural potential. This study, comprising 100 Egyptian patients aged 37-81, compares the predictive efficacy of various CTO scoring systems in PCI success determination. Patients with CTO in at least one coronary artery, planned for elective PCI based on objective evidence of ischemia, were included...
March 5, 2024: Egyptian Heart Journal: EHJ
https://read.qxmd.com/read/38440643/superior-semicircular-canal-dehiscence-a-radiological-and-clinical-study
#8
JOURNAL ARTICLE
Waleed Moneir, Ahmed Yasser Darwish, Yasser Wafeek Khafagy, Mahmoud Attia Youssef, Mohammed Magdy El Rakhawy, Ahmed Hemdan
AIM: to assess radiologically the prevalence of SSCD with its clinical presentations and its relationship with age. METHODS: a prospective cohort study carried out on 200 consecutive patients (400 temporal bones). Radiological evaluation was performed using High Resolution Computed Tomography (HRCT) with measurement of thickness of bone covering superior semicircular canal (SCC), height and diameter of SSC. RESULTS: Two hundred patients (400 temporal bones) were involved...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440634/role-of-loupes-magnification-in-tracheal-resection-and-anastomosis
#9
JOURNAL ARTICLE
Ahmed Yahia Yahia Fouda, Hussein Magdy Abdelkader, Esmail Hassan Ramadan Ahmed, Marwan Ahmed Ibrahim
UNLABELLED: Tracheal resection and anastomosis is characterized in the last years by significant innovations which are well codified and standardized. Although the mortality rate is markedly reduced, the operation is still not free from risk of complications such as recurrent laryngeal nerve injury, anastomosis dehiscence, granulation tissue formation and restenosis. Pearson FG, Cooper ID, Nelems JL (1975) Primary tracheal anastomosis after resection of the cricoide cartilage with preservation of the recurrent laryngeal nerves...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440444/prevalence-of-chronic-middle-ear-effusion-in-cases-of-cleft-palate
#10
JOURNAL ARTICLE
Hussein Magdy Abdelkader, Marwan Ahmed Ibrahim, Esmail Hassan Ramadan Ahmed, Ahmed Yahia Yahia Fouda
Chronic middle ear effusion is generally present in children with cleft palate (CP) associated with or without cleft lips. The aim of our study was to assessment of how common middle ear effusion is in patients with cleft palates and to evaluate the presence of these symptoms by performing a Basic Audiological Evaluation (BAE). A retrospective randomized study was conducted on 50 children (29 male and 21 female) aged 2 to 16 years who had CPs (associated with or without cleft lips) with symptoms of middle ear effusion...
February 2024: Indian Journal of Otolaryngology and Head and Neck Surgery
https://read.qxmd.com/read/38440292/a-comprehensive-survey-of-warfarin-induced-hepatic-toxicity-using-histopathological-biomarker-and-molecular-evaluation
#11
JOURNAL ARTICLE
Mona M Atia, Heba Allah Ahmed Mahmoud, Magdy Wilson, Elham A Abd-Allah
Warfarin finds human application as anticoagulant therapy. Warfarin usage can cause liver damage and hemorrhage. Besides functioning as anticoagulant and causing continuous bleeding of pests, the mechanism of toxicity of warfarin is unknown. In this study, Wild female and male rats were administrated orally with warfarin for 18 days at 9, 18, 27.5, and 55 mg/kg, respectively. Hepatoxicity was determined by assessing, LD50, leukocyte counts, immunochemistry, histopathology, serum proteins, Western blotting, especially of markers of liver injury, such as AST, ALT & ALP, and markers of antioxidant and oxidative stress markers...
February 29, 2024: Heliyon
https://read.qxmd.com/read/38432408/targeting-sirt1-nlrp3-inflammasome-and-nrf2-signaling-with-chrysin-alleviates-the-iron-triggered-hepatotoxicity-in-rats
#12
JOURNAL ARTICLE
Samyah T Alanazi, Samir A Salama, Ahmed Magdy El-Ebiary, Abdulelah K Altowairqi, Atheer T Alharthi, Shahad M Alzahrani, Shomokh H Althagafi, Reema A Alotaibi, Ahmed Abd-Eltawab Tammam
Blood transfusion-requiring diseases such as sickle cell anemia and thalassemia are characterized by an imbalance between iron intake and excretion, resulting in an iron overload (IOL) disorder. Hepatotoxicity is prevalent under the IOL disorder because of the associated hepatocellular redox and inflammatory perturbation. The current work was devoted to investigate the potential protection against the IOL-associated hepatotoxicity using chrysin, a naturally-occurring flavone. IOL model was created in male Wistar rats by intraperitoneal injection of 100mg/kg elemental iron subdivided on five equal injections; one injection was applied every other day over ten days...
March 1, 2024: Toxicology
https://read.qxmd.com/read/38421613/peptide-nucleic-acid-assisted-generation-of-targeted-double-stranded-dna-breaks-with-t7-endonuclease-i
#13
JOURNAL ARTICLE
Rashid Aman, Muntjeeb M Syed, Ahmed Saleh, Firdaws Melliti, Sivakrishna Rao Gundra, Qiaochu Wang, Tin Marsic, Ahmed Mahas, Magdy M Mahfouz
Gene-editing technologies have revolutionized biotechnology, but current gene editors suffer from several limitations. Here, we harnessed the power of gamma-modified peptide nucleic acids (γPNAs) to facilitate targeted, specific DNA invasion and used T7 endonuclease I (T7EI) to recognize and cleave the γPNA-invaded DNA. Our data show that T7EI can specifically target PNA-invaded linear and circular DNA to introduce double-strand breaks (DSBs). Our PNA-Guided T7EI (PG-T7EI) technology demonstrates that T7EI can be used as a programmable nuclease capable of generating single or multiple specific DSBs in vitro under a broad range of conditions and could be potentially applied for large-scale genomic manipulation...
February 29, 2024: Nucleic Acids Research
https://read.qxmd.com/read/38415551/immunohistochemical-expression-of-claudin-1-and-claudin-4-in-urothelial-carcinoma-of-the-urinary-bladder
#14
JOURNAL ARTICLE
Aya Magdy Elsayed, Eman Ibrahim Mahmoud, Mostafa Mohamed Salem, Rasha Ahmed Khairy
BACKGROUND: In Egypt, bladder cancer occupies the second rankamong reported cancers in men. Claudins are tight junctions that have a critical role in tumor pathogenesis, invasion, progression, and metastasis and currentlyare a focus of interest for targeting therapies. OBJECTIVES: We aimed to evaluatethe immunohistochemical expression of Claudin-1 and Claudin-4 in urinary bladder urothelial carcinoma and investigate the relationshipbetweenthe expressed Claudins with differentclinicopathological parameters...
February 1, 2024: Asian Pacific Journal of Cancer Prevention: APJCP
https://read.qxmd.com/read/38415336/challenges-and-epidemiological-implications-of-the-first-outbreak-of-dengue-and-chikungunya-in-sudan
#15
JOURNAL ARTICLE
Setalnafer Magdy Aljaily, Ismail Ali Yousif Hamed, Khalid Sarour Mustafa, Osama Salah Basher Ishag, Ezeirig Awad Ezeirig Musa, Abdel Kreem Ahmed, Eiman Mohmmed Adam Ibrahim, Rasha Siddig Azrag
BACKGROUND: Dengue and chikungunya are mosquito-borne infections that are spreading rapidly worldwide. The highest burden lies in tropical and subtropical countries. In 2022 Sudan encountered the most widespread infection of both diseases. AIM: To describe the magnitude of the first outbreak of dengue and chikungunya infections in Tandalti Town, White Nile State, southern part of Sudan. METHODS: Following the report of a high number of undifferentiated febrile illnesses in 32 health clinics in Tandalti Town, an area with high densities of Aedes aegypti, we collected blood samples from symptomatic suspected cases...
January 21, 2024: Eastern Mediterranean Health Journal
https://read.qxmd.com/read/38404663/structural-aortic-wall-abnormalities-following-the-nikaidoh-operation-which-could-be-reversible-and-include-a-healing-process
#16
Magdi H Yacoub, Ahmed Afifi, Hatem Hosny, Ahmed Mahgoub, Mohamed Nagy, Sanida Vaz, Padmini Sarathchandra, Najma Latif
The Nikaidoh operation continues to be used for patients with transposition of the great arteries, ventricular septal defect and left ventricular outflow tract obstruction. We recently reported structural and functional changes in the aortic root during the follow-up of a patient who underwent the Nikaidoh operation. These changes necessitated re-operation. The pathophysiology of these changes and their potential for reversibility have not yet been studied. In this communication, we describe the extensive structural changes in the aortic wall of the same patient...
January 3, 2024: Global Cardiology Science & Practice
https://read.qxmd.com/read/38403671/effectiveness-and-safety-of-mexiletine-versus-placebo-in-patients-with-myotonia-a-systematic-review-and-meta-analysis
#17
JOURNAL ARTICLE
Abdelrahman Mohammed Elettreby, Ahmed Abdullah Abo Elnaga, Mohamed Ahmed Alsaied, Dalia Kamal Ewis, Aya Mohammed Sharkawy, Rahma Fareed, Gehad Magdy Alderbi
BACKGROUND: The rare nature of dystrophic and non-dystrophic myotonia has limited the available evidence on the efficacy of mexiletine as a potential treatment. To address this gap, we conducted a systematic review and meta-analysis to evaluate the effectiveness and safety of mexiletine for both dystrophic and non-dystrophic myotonic patients. METHODS: The search was conducted on various electronic databases up to March 2023, for randomized clinical trials (RCTs) comparing mexiletine versus placebo in myotonic patients...
February 26, 2024: Neurological Sciences
https://read.qxmd.com/read/38400624/absorbable-antibiotic-beads-for-treatment-of-lvad-driveline-infections
#18
Ishaq Wadiwala, Pankaj Garg, Emad Alamouti-Fard, Kevin Landolfo, Basar Sareyyupoglu, Magdy El-Sayed Ahmed, Samuel Jacob, Si Pham
BACKGOUND: Infections of the left ventricular assist device (LVAD) driveline are a dreaded complication that results in high mortality and morbidity. METHOD: We retrospectively reviewed five consecutive patients with severe continuous-flow LVAD (HVAD, Heartmate 2, and Heartmate 3) driveline infection. These infections, which developed on an average of 960.4 ± 843.9 days after LVAD placement, were refractory to systemic antibiotics and local wound care...
February 23, 2024: Artificial Organs
https://read.qxmd.com/read/38392232/mapping-the-landscape-of-the-digital-workflow-of-esthetic-veneers-from-design-to-cementation-a-systematic-review
#19
REVIEW
Walaa Magdy Ahmed, Amr Ahmed Azhari, Lamer Sedayo, Alanod Alhaid, Reem Alhandar, Amirah Almalki, Aishah Jahlan, Afnan Almutairi, Waad Kheder
The purpose of this systematic review was to map all the existing literature on digitally designed and fabricated esthetic veneers. We aimed to compare the accuracy of digitally designed preparation and cementation guides for esthetic indirect veneers with the conventional workflow. We evaluated studies comparing the accuracy and predictability of workflows between digitally fabricated indirect-esthetic veneers and conventional indirect veneers. Searches were performed in August 2023 across three databases, specifically Google Scholar, Cochrane, and PubMed, and were restricted to English-language publications...
January 31, 2024: Dentistry Journal
https://read.qxmd.com/read/38381003/the-effects-of-genetic-polymorphism-on-toxicity-and-pharmacokinetics-of-methotrexate-in-egyptian-adult-patients-with-leukaemia-or-lymphoma
#20
JOURNAL ARTICLE
Khloud Shendy, Khaled Abdelkawy, Ahmed Amin Ali, Fathalla Belal, Mostafa Abdelhakiem, Galal Magdy, Nahla Anber, Fawzy Elbarbry
1. Polymorphisms in genes coding folate-metabolizing enzymes might alter the pharmacokinetics and sensitivity for methotrexate "MTX". 2. The aim of the study aimed to investigate the influence of MTHFR C677T, DHFR19 Ins/del, GGH -401 C > T, and MTR A2756G polymorphisms on MTX toxicity and pharmacokinetics in Egyptian patients with Acute lymphoblastic leukaemia (ALL) or Non-Hodgkin lymphoma (NHL). 3. Fifty adult Egyptian patients with ALL and NHL, treated with high dose MTX, were prospectively enrolled in the study...
February 21, 2024: Xenobiotica; the Fate of Foreign Compounds in Biological Systems
keyword
keyword
109503
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.