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ahmed magdy

Ahmed Zaki Mohamed Anwar, Tarek Khalaf Fathelbab, Amr Mohamed Abdelhamid, Ehab Mohmed Galal, Mostafa Magdi Ali, Ehab Rifat Tawfiek
PURPOSE: We evaluated the role of initial laparoscopy and optimized approach in cases of unilateral nonpalpable testis. METHODS: Seventy-four patients with nonpalpable testes were presented. We excluded 9 patients, with palpable testes under anesthesia. Laparoscopy was offered to 65 patients. Contralateral testis hypertrophy with length ≥ 1.8 cm was confirmed in 47 patients. Ultrasound results were available for 35 patients. RESULTS: Age ranged from 1 to 10 years...
October 11, 2018: International Urology and Nephrology
Mai Ahmed Tawfik, Mina Ibrahim Tadros, Magdy Ibrahim Mohamed
Vardenafil hydrochloride is commonly used for the curing of erectile dysfunction. VAR suffers certain limitations: (i) short elimination half-life (4-5 h), (ii) low aqueous solubility (0.11 mg/mL), (iii) susceptibility to extensive first-pass metabolism and drug efflux transporters (P-glycoprotein), and (iv) limited (15%) oral bioavailability. The current study focused on the development of VAR lipomers as promising modified release systems able to enhance oral bioavailability. VAR-lipomers (lipid-polymer complexes) were successfully developed by a modified precipitation technique employing a lipid (polyglyceryl-6-distearate or glyceryl tristearate) and an amphiphilic polymer (Gantrez®)...
October 5, 2018: AAPS PharmSciTech
Nishat Ahmed, Naif Aljuhani, Hind S Al-Hujaili, Manar A Al-Hujaili, Mohamed A Elkablawy, Magdy M Noah, Hany Abo-Haded, Dina S El-Agamy
Valproate is a widely used drug against epilepsy and several other neurological disorders although it has deleterious hepatotoxic side effects. The current study was designed to test if agmatine as nitric oxide modulator has protective effects against valproate-induced hepatic injury. Male Swiss albino mice were treated with sodium valproate (SVP) with or without agmatine for 7 days. Serum and liver samples were collected for analysis. Results have revealed that agmatine exerted hepatoprotective effects against SVP-associated hepatic injury...
October 1, 2018: Journal of Biochemical and Molecular Toxicology
Bashir A Yousef, Amina I Dirar, Mohamed Ahmed A Elbadawi, Mohamed K Awadalla, Magdi A Mohamed
Background: Plants of the Amaryllidaceae family have been under intense scrutiny for the presence of a couple of alkaloidal secondary metabolites with endued cytotoxic activity, such as pancratistatin ( 1 ), 7-deoxypancratistatin ( 2 ), narciclasine ( 3 ), 7-deoxynarciclasine ( 4 ), trans -dihydronarciclasine ( 5 ), and 7-deoxy- trans -dihydronarciclasine ( 6 ). Nevertheless, preclinical evaluation of these alkaloids has been put on hold because of the limited quantity of materials available from isolation...
July 2018: Journal of Pharmacy & Bioallied Sciences
Ashraf M Reda, Ayman Elgendi, Ahmed Ismail Ebraheem, Mohammed S Aldraibi, Mohammed Saleh Qari, Magdy Mohammad R Abdulghani, Thomas Luger
Background There is a need for safe, effective treatment for atopic dermatitis (AD) in the Middle East. Objective To propose a practical algorithm for the treatment of AD throughout the Middle East. Methods An international panel of six experts from the Middle East and one from Europe developed the algorithm. The practical treatment guide was based on a review of published guidelines on AD, an evaluation of relevant literature published up to August 2016 and local treatment practices. Results Patients with an acute mild-to-moderate disease flare on sensitive body areas should apply the topical calcineurin inhibitor (TCI), pimecrolimus 1% cream twice daily until clearance...
September 17, 2018: Journal of Dermatological Treatment
Nesreen Ali, Seham Gohar, Iman Zaky, Ahmed Elghoneimy, Sarah Youssef, Gehad Sameer, Dina Yassin, Sherine Salem, Hadeel Magdi, Iman Sidhom
BACKGROUND: As survival rates for children with acute lymphoblastic leukemia (ALL) improve, awareness of treatment complications becomes important. Osteonecrosis (ON) is a serious disabling complication in treated ALL patients. The aim of the study was to define the frequency of ON identified by magnetic resonance imaging (MRI) and to study the risk factors for ON. PATIENTS AND METHODS: The frequency of ON was evaluated retrospectively in 858 patients with ALL who were diagnosed at Children's Cancer Hospital of Egypt from January 2009 to December 2012...
September 5, 2018: Pediatric Blood & Cancer
Mahmoud Hassanein, Magdy Abdelhamid, Bassem Ibrahim, Mohamed Sobhy, Gamela Nasr, Mohamed Wafaie Aboleineen, Ashraf Reda, Nabil Farag, Ahmed Elshazly, Tarek Khairy Abdeldayem, Fatma Elmesseiry, Hesham Boshra, Hesham Sobhy, Atef Elbahry, Amr Youssef, Medhat Ashmawy, Ahmed Abdelmoneim, Ayman Saleh, Yahya Elrakshy, Hamdy Ebeid
AIMS: This analysis evaluates gender differences in the Egyptian cohort of patients hospitalized for acute heart failure (AHF) in the European Society of Cardiology Heart Failure Long-Term Registry. METHODS AND RESULTS: From April 2011 to September 2014, 1634 patients hospitalized with AHF were enrolled by 20 hospitals all over Egypt. Of these patients, 1112 (68%) patients were male and 522 (32%) were female. Women presented with a higher admission systolic blood pressure and resting heart rate...
September 3, 2018: ESC Heart Failure
Mohamed Mohamed, Ehab Abdel Aziz El-Shaarawy, Magdy Youakim, Doaa Shuaib, Mai Ahmed
BACKGROUND: Degenerative changes caused by aging may affect the eye specially the retina. Such changes occurs as a part of normal physiological process and may be irreversible. AIM: The aim of the study was to demonstrate the influence of aging on the morphology of the retina to provide a basis to explain the pathogenesis of age-associated decline in visual acuity, scotopic and photopic sensitivity. MATERIALS AND METHODS: Forty male albino rats were used and divided into four age groups; group I: age of cortical maturity, group II: middle-aged, group III: aged group and group IV: senile group...
August 29, 2018: Folia Morphologica (Warsz)
Mohamed El Kassas, Mohamed Alboraie, Kadry Elsaeed, Yasmeen Ahmed, Adel El Tahan, Omkolsoum Alhaddad, Mohamed Salaheldin, Ibrahim Kabbash, Mohamed El Badry, Talaat Fathy, Magdy El-Serafy, Yehia ElShazly, Wahid Doss, Gamal Esmat
No abstract text is available yet for this article.
November 2018: American Journal of Therapeutics
Ahmed Mohamed El Ghoneimy, Magdy El Sherbiny, Nehal Kamal
BACKGROUND:  Most reports on skeletal reconstruction using vascularized fibular free flap include patients with varying age groups and anatomic locations. This study has limited the inclusion criteria to pediatric and adolescent patients diagnosed with bone sarcoma of the femoral shaft. METHODS:  Forty-one patients, diagnosed with a malignant bone tumor of the femoral shaft (21 Ewing's sarcomas and 20 osteosarcomas), were locally treated by joint sparing wide resection and reconstruction using a vascularized fibular free flap...
August 18, 2018: Journal of Reconstructive Microsurgery
Ahmed Ali, Walid H Kilany, Mohamed A Zain El-Abideen, Magdy El Sayed, Magdy Elkady
Vaccination programs against infectious bronchitis virus (IBV) in Egypt depend on both classical and/or imported variant IBV strain vaccines. However, many IBV outbreaks associated with respiratory distress, nephropathy, and high mortalities were attributed to the circulation of both classical and new nephropathogenic IBV variant 2 strains. In the present study, we report the development of attenuated IBV candidate vaccines using the classic IBV strains (IBM41 and IB2) and a nephropathogenic strain (IBvar2)...
August 6, 2018: Poultry Science
Ahmed Mahmoud Abdou, Islam Mohamed Magdi Ammar, Amr Abd Almohsen Alnemr, Amr Ahmed Abdelrhman
Objective: To compare the efficacy and safety of dienogest (DNG) with depot leuprolide acetate (LA) in patients with recurrent pelvic pain following laparoscopic surgery for endometriosis. Design: Prospective randomized trial. Setting: Zagazig University hospitals, Egypt. Patients: Two hundred and forty-two patients with recurrent pelvic pain following laparoscopic surgery for endometriosis. Intervention: Dienogest (2 mg/day, orally) or depot LA (3...
August 2018: Journal of Obstetrics and Gynaecology of India
Monika Magdy, Tarek Hussein, Ahmed Ezzat, Ahmed Gaballah
BACKGROUND: Gastric cancer is the fifth cancer worldwide. Inflammatory response increases metastasis through apoptosis inhibition and angiogenesis augmentation. The neutrophil-lymphocyte ratio (NLR), which is a balance between pro-cancer inflammatory and anti-cancer immune responses, was proved as prognostic marker. Peripheral NLR is a good reflection of tumor microenvironment. METHODS: We retrospectively collected data of gastric and gastro-esophageal cancer patients treated from January 2015 till December 2016...
July 30, 2018: Journal of Gastrointestinal Cancer
Ahmed Abdel Khalek Abdel Razek, Mohamed Magdy Elrakhawy, Mahmoud Mohamed Yossof, Hadeer Mohamed Nageb
Purpose: To assess inter-observer variability of the Coronary Artery Disease - Reporting and Data System (CAD-RADS) for classifying the degree of coronary artery stenosis in patients with stable chest pain. Material and methods: A prospective study was conducted upon 96 patients with coronary artery disease, who underwent coronary computed tomography angiography (CTA). The images were classified using the CAD-RAD system according to the degree of stenosis, the presence of a modifier: graft (G), stent (S), vulnerable plaque (V), or non-diagnostic (n) and the associated coronary anomalies, and non-coronary cardiac and extra-cardiac findings...
2018: Polish Journal of Radiology
Ahmed Mahas, Magdy Mahfouz
In prokaryotes, CRISPR/Cas adaptive immunity systems target and destroy nucleic acids derived from invading bacteriophages and other foreign genetic elements. In eukaryotes, the native function of these systems has been exploited to combat viruses in mammals and plants. Rewired CRISPR/Cas9 and CRISPR/Cas13 systems have been used to confer resistance against DNA and RNA viruses, respectively. Here, we discuss recent approaches employing CRISPR/Cas systems to combat viruses in eukaryotes, highlight key challenges, and provide future perspectives...
July 10, 2018: Current Opinion in Virology
Ghada M Mansour, Sherif H Hussein, Rasha M Abd El Hady, Haitham F Mohammed, Magdy M Abd El Gawad, Ahmed I Abou Gabal, Rania M Al-Awadhy, Mohamed El Saied
PURPOSE: To assess the subendometrial and uterine artery blood flow and pattern of the waveform of the uterine artery in cases of recurrent pregnancy loss compared with normal controls. SUBJECTS AND METHODS: Fifty women with a history of two or more successive pregnancy losses were investigated by Doppler transvaginal ultrasound to assess the subendometrial blood flow resistance index (RI), type of Doppler waveform of the uterine artery, and uterine artery pulsatility index (PI) in the mid-luteal phase...
August 6, 2018: Journal of Maternal-fetal & Neonatal Medicine
Magdy Ahmed Abd-Al-Moktader
BACKGROUND:  Peroneus brevis muscle flap is a distinguished, distally based safe flap that can be manipulated to cover small defects in the leg and ankle. For large-sized defects, a more distal, larger flap is required either locally or distantly. METHODS:  Forty-two distally based peroneus brevis muscle flaps were elevated in 42 patients (30 males and 12 females) with major lower leg, ankle, and proximal foot defects of 6 to 15 cm in length and 6 to 12 cm in width...
October 2018: Journal of Reconstructive Microsurgery
Ahmed Hemdan, Ragaa Magdy, Maha Farouk
Interest in implementing green chemistry principles in analytical chemistry has grown dramatically in the past few years. The solvents used have the major influence on the greenness of the method. Most conventional high-performance liquid chromatography methods employed utilize solvents that are "hazardous for the environment". In the present study, two-factor three-level response surface design was exploited to develop eco-friendly chromatographic methods for two different mixtures. The first one was atorvastatin and amlodipine and the second one was amlodipine, perindopril, and indapamide...
August 2018: Journal of Separation Science
Islam Abdelmoneim, Ayman Sadek, Mohamed Ahmed Mosaad, Ibrahim Yassin, Yasser Radwan, Khalid Shokry, Ahmed Magdy, Mohammed Yasser Elsherbeny, Abdelrahman Ibrahim Abushouk
We performed this study to compare the sensitivity and specificity of multi-slice computed tomography (MSCT) to coronary angiography (CA) in detecting coronary total occlusion (CTO) lesion characteristics. Moreover, we analyzed the association between these characteristics and the risk of revascularization failure. Fifty patients with confirmed CTO diagnosis were tried for revascularization using the antegrade (all 50) or retrograde (in failed nine antegrade interventions) approaches. Each patient underwent CA and MSCT before the intervention and data from both modalities were compared using the SPSS software...
November 2018: International Journal of Cardiovascular Imaging
Hail M Al-Abdely, Yassir Khidir Mohammed, Victor D Rosenthal, Pablo W Orellano, Mohamed ALazhary, Eman Kaid, Anan Al-Attas, Ghadeer Hawsawi, Ashraf Kelany, Bedoor Hussein, Bayan Esam, Rami Altowerqi, Modhi A Alkamaly, Nader A Tawfic, Elinita Cruzpero, Raya M Al Rashidi, Reny Thomas, Apsia M Molano, Hessa A Al Enazy, Fatima M Al Adwani, Arlu M Casuyon Pahilanga, Sharifa Alatawi, Raslan Nakhla, Fatma M Al Adwani, Rosita Gasmin Aromin, Evangelina Balon Ubalde, Hanan Hanafy Diab, Nahla A Kader, Ibtesam Y Hassan Assiry, Fahad A Sawan, Hassan E Ammari, Alhasan M Mashiakhy, Elaine B Santiago, Christian M S Chua, Imee M Dalis, Haider M Arishi, Ruthelma Lozada, Ibrahim A M Al-Zaydani Asiri, Hala Ahmed, Al Jarie, Ali S M Al-Qathani, Halima Y Al-Alkami, Mervat AlDalaton, Siti J B Alih, Mohammed J Alaliany, Najla J Helali, Grace Sindayen, Annalyn A Malificio, Haya B Al Dossari, Abdulmajid G Algethami, Dia Mohamed, Leigh Yanne, Avigail Tan, Sheema Babu, Shatha M Abduljabbar, Hala Rushdi, Janice Fernandez, Waleed M Hussain, Renuga D Rajavel, Syed Z Bukhari, Abdullah A Turkistani, Jeyashri J Mushtaq, Eida Albeladi, Sally Aboushoushah, Nahed Qushmaq, Leide Shyrine, Jomol Philipose, Mohamed Raees, Nawal S AbdulKhalik, Marjory Madco, Mohd Abdulghany, Athena Manao, Catherine Acostan, Rania Safwat, Muhammad Halwani, Nahla A H Abdul Aal, Anumol Thomas, Shaymaa M Abdulatif, Nelia C Ariola, Aisha H Mutwalli, Nelia Ariola, Eatedal Bohlega, Saly Simon, Estelita Damlig, Sherin G Elsherbini, Ilama T Krishne, Sheela Abraham, Mohammed A Ali Karrar, Nisreen A Gosn, Abdulaziz A Al Hindi, Rasha N Jaha, Saeda M AlQahtani, Ali O Abdul Aziz, Nadia L Demaisip, Elizabeth Laungayan Cortez, Analen F Cabato, Jerlie M Gonzales Celiz, Mohammed A Al Raey, Saeed A Al Darani, Misbah R Aziz, Batool A Manea, Eslam Samy, Solita Briones, Radhika Krishnan, Saman S M Raees, Kehkashan Tabassum, Khalid M Ghalilah, Mohamed Alradady, Abdulrahim Al Qatri, Mafaten Chaouali, Magdy Elsisi, Hajer A Aldossary, Shehab Al-Suliman, Amina A Al Talib, Nadira Albaghly, Mohammad E Haqlre Mia, Manal M Al-Gethamy, Dhafer M Alamri, Adnan S Al-Saadi, Evelyn P Ayugat, Nawaf A Al Hazazi, Modi I Al Hussain, Yvonne Caminade, Ann J Santos, Mohamed H Abdulwahab, Bushra T A Al-Garni
BACKGROUND: To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and use of INICC Surveillance Online System (ISOS) on ventilator-associated pneumonia (VAP) rates in Saudi Arabia from September 2013 to February 2017. METHODS: A multicenter, prospective, before-after surveillance study on 14,961 patients in 37 intensive care units (ICUs) of 22 hospitals. During baseline, we performed outcome surveillance of VAP applying the definitions of the CDC/NHSN...
September 2018: Journal of Infection and Public Health
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