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ahmed magdy

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https://www.readbyqxmd.com/read/28894525/evaluation-of-cd44-and-cd133-as-markers-of-liver-cancer-stem-cells-in-egyptian-patients-with-hcv-induced-chronic-liver-diseases-versus-hepatocellular-carcinoma
#1
Mohammed Saeed Rozeik, Olfat Ali Hammam, Ali Ibrahim Ali, Mona Magdy, Heba Khalil, Amgad Anas, Ahmed Abdelaleem Abo El Hassan, Ali Abdel Rahim, Ahmed Ibrahim El-Shabasy
BACKGROUND: Cancer stem cells (CSCs) play a critical role in tumor development, progression, metastasis and recurrence. AIM: To evaluate hepatic expression of CD44 and CD133 in Egyptian patients with HCV-induced chronic liver diseases and hepatocellular carcinomas (HCCs), and to assess its correlation with inflammatory activity scores, stages of fibrosis (in chronic hepatitis with or without cirrhosis) and grades of HCC. METHODS: This prospective case-control study was conducted on eighty subjects who attended the Tropical Diseases Department, Al-Azhar University Hospital, and in collaboration with Theodor Bilharz Research Institute (2014-2016)...
July 2017: Electronic Physician
https://www.readbyqxmd.com/read/28887660/urinary-interleukin-22-binding-protein-as-a-marker-of-lupus-nephritis-in-egyptian-children-with-juvenile-systemic-lupus-erythematosus
#2
Ahmed Mohamed Mahmoud Badr, Yomna Farag, Maie Abdelshafy, Nermine Magdi Riad
Juvenile systemic lupus erythematosus (JSLE) is a multi-system autoimmune inflammatory disease. Generally, 60% of patients will develop lupus nephritis (LN); thus, early recognition and treatment is associated with better outcome. Interleukin 22 (IL-22) is involved in tissue inflammation and is regulated by interleukin 22 binding protein (IL-22BP). This study aimed to use IL-22BP as a non-invasive marker for disease activity in JSLE and LN. This is a cross-sectional study conducted on 82 subjects: 51 JSLE patients and 31 healthy controls of matched age and gender...
September 9, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28878865/micrornas-and-clinical-implications-in-hepatocellular-carcinoma
#3
Amal Ahmed Mohamed, Zainab A Ali-Eldin, Tamer A Elbedewy, Magdy El-Serafy, Fatma A Ali-Eldin, Hossameldin AbdelAziz
AIM: To assess the role of some circulating miRNAs (miR-23a, miR-203, miR338, miR-34, and miR-16) as tumor markers for diagnosis of hepatocellular carcinoma (HCC). METHODS: One hundred and seventy-one subjects were enrolled, 57 patients with HCC, 57 patients with liver cirrhosis (LC) and 57 healthy subjects as control group. Severity of liver disease was assessed by Child Pugh score. Tumor staging was done using Okuda staging system. Quantification of Micro RNA (miR-23a, miR-203, miR338, miR-34, and miR-16) was performed...
August 18, 2017: World Journal of Hepatology
https://www.readbyqxmd.com/read/28873075/intraoperative-magnesium-sulphate-decreases-agitation-and-pain-in-patients-undergoing-functional-endoscopic-surgery-a-randomised-double-blind-study
#4
Hazem E Elsersy, Magdy Ch Metyas, Hana A Elfeky, Ahmed A Hassan
BACKGROUND: Postoperative agitation is harmful for the patient as it may be associated with removal of catheters, nasal packs, oxygen masks and self-injury, and pose a danger to operating theatre staff. OBJECTIVE: The current study investigated the potential role of magnesium sulphate in treatment of postoperative agitation following functional endoscopic sinus surgery. DESIGN: A randomised, double-blinded, placebo-controlled trial. SETTING: ENT operating room, Menofia University Hospitals, Egypt...
October 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28836953/efficacy-and-safety-of-transcatheter-aortic-valve-replacement-in-aortic-stenosis-patients-at-low-to-moderate-surgical-risk-a-comprehensive-meta-analysis
#5
Ahmed Elmaraezy, Ammar Ismail, Abdelrahman Ibrahim Abushouk, Moutaz Eltoomy, Soha Saad, Ahmed Negida, Osama Mahmoud Abdelaty, Ahmed Ramadan Abdallah, Ahmed Magdy Aboelfotoh, Hossam Mahmoud Hassan, Aya Gamal Elmaraezy, Mahmoud Morsi, Farah Althaher, Moath Althaher, Ammar M AlSafadi
BACKGROUND: Recently, transcatheter aortic valve replacement (TAVR) has become the procedure of choice in high surgical risk patients with aortic stenosis (AS). However, its value is still debated in operable AS cases. We performed this meta-analysis to compare the safety and efficacy of TAVR to surgical aortic valve replacement (SAVR) in low-to-moderate surgical risk patients with AS. METHODS: A systematic search of five authentic databases retrieved 11 eligible studies (20,056 patients)...
August 24, 2017: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/28816075/psychological-impact-of-female-genital-mutilation-among-adolescent-egyptian-girls-a-cross-sectional-study
#6
Magdy R Ahmed, Mohamed M Shaaban, Heba K Meky, Mohamed E Amin Arafa, Tamer Y Mohamed, Waleed F Gharib, Abeer B Ahmed
OBJECTIVES: Worldwide, at least 200 million women and girls have undergone female genital mutilation (FGM). The medical and sexual consequences have been documented, but the psychological impact has not been studied to the same extent. The aim of this study was to explore the relationship between FGM and psychiatric problems among adolescent girls. METHODS: A total of 204 girls, aged 14-19 years, were included in a cross-sectional study conducted at Suez Canal University Hospitals...
August 17, 2017: European Journal of Contraception & Reproductive Health Care
https://www.readbyqxmd.com/read/28816063/acute-cardiovascular-care-association-position-paper-on-intensive-cardiovascular-care-units-an-update-on-their-definition-structure-organisation-and-function
#7
Eric Bonnefoy-Cudraz, Hector Bueno, Gianni Casella, Elia De Maria, Donna Fitzsimons, Sigrun Halvorsen, Christian Hassager, Zaza Iakobishvili, Ahmed Magdy, Toomas Marandi, Jorge Mimoso, Alexander Parkhomenko, Susana Price, Richard Rokyta, Francois Roubille, Pranas Serpytis, Avi Shimony, Janina Stepinska, Diana Tint, Elina Trendafilova, Marco Tubaro, Christiaan Vrints, David Walker, Doron Zahger, Endre Zima, Robert Zukermann, Maddalena Lettino
Acute cardiovascular care has progressed considerably since the last position paper was published 10 years ago. It is now a well-defined, complex field with demanding multidisciplinary teamworking. The Acute Cardiovascular Care Association has provided this update of the 2005 position paper on acute cardiovascular care organisation, using a multinational working group. The patient population has changed, and intensive cardiovascular care units now manage a large range of conditions from those simply requiring specialised monitoring, to critical cardiovascular diseases with associated multi-organ failure...
August 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/28780707/evidence-for-association-between-hepatitis-c-virus-and-parkinson-s-disease
#8
REVIEW
Abdelrahman Ibrahim Abushouk, Mostafa Wanees Ahmed El-Husseny, Mayar Magdy, Ammar Ismail, Attia Attia, Hussien Ahmed, Ravikishore Pallanti, Ahmed Negida
Parkinson's disease (PD) is a globally prevalent neurodegenerative disorder, characterized by progressive neuronal loss in the substantia nigra and formation of Lewy bodies. These pathological characteristics are clinically translated into motor symptoms, such as bradykinesia, rigidity, resting tremors, and postural instability. Emerging data from epidemiological studies suggest a possible association between PD and hepatitis C virus (HCV) infection, which affects up to 71 million individuals worldwide. Preclinical studies have shown that HCV can penetrate and replicate within the brain macrophages and microglial cells, increasing their production of pro-inflammatory cytokines that can directly cause neuronal toxicity...
August 5, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/28753649/pregnant-women-carrying-female-fetuses-are-at-higher-risk-of-placental-malaria-infection
#9
Ishag Adam, Magdi M Salih, Ahmed A Mohmmed, Duria A Rayis, Mustafa I Elbashir
BACKGROUND: The pathophysiology of the placental malaria is not fully understood. If there is a fetal sex-specific susceptibility to malaria infection, this might add to the previous knowledge on the immunology, endocrinology and pathophysiology of placental malaria infections. AIMS: This study was conducted to assess whether the sex of the fetus was associated with placental malaria infections. SUBJECTS AND METHODS: A cross-sectional study was performed including a secondary analysis of a cohort of women who were investigated for prevalence and risk factors (including fetal sex) for placental malaria in eastern Sudan...
2017: PloS One
https://www.readbyqxmd.com/read/28751912/efficacy-and-safety-of-topical-corticosteroids-for-management-of-oral-chronic-graft-versus-host-disease
#10
REVIEW
Basma Abdelaleem Elsaadany, Eman Magdy Ahmed, Sana Maher Hasan Aghbary
BACKGROUND: Oral chronic graft versus host disease (cGVHD) is a major complication in transplantation community, a problem that can be addressed with topical intervention. Topical corticosteroids are the first line of treatment although the choice remains challenging as none of the available treatments is supported by strong clinical evidence. OBJECTIVE: This systematic review aims to determine the clinical efficacy and safety of topical corticosteroids for the management of the mucosal alterations of oral cGVHD...
2017: International Journal of Dentistry
https://www.readbyqxmd.com/read/28733244/response-surface-optimization-ex-vivo-and-in-vivo-investigation-of-nasal-spanlastics-for-bioavailability-enhancement-and-brain-targeting-of-risperidone
#11
Fatma Elzahraa Abdelrahman, Ibrahim Elsayed, Mary Kamal Gad, Ahmed Hassen Elshafeey, Magdi Ibrahim Mohamed
Transnasal brain drug targeting could ensure better drug delivery to the brain through the olfactory pathway. Risperidone bioavailability is 66% in extensive metabolizers and 82% in slow metabolizers. The aim of this study is to investigate the ability of the nanovesicular spanlastics to effectively deliver risperidone through the nasal route to the brain and increase its bioavailability. Spanlastics formulae, composed of span and polyvinyl alcohol, were designed based on central composite statistical design...
July 18, 2017: International Journal of Pharmaceutics
https://www.readbyqxmd.com/read/28729881/outcomes-following-repair-of-incarcerated-and-strangulated-ventral-hernias-with-or-without-synthetic-mesh
#12
Sameh Hany Emile, Hesham Elgendy, Ahmad Sakr, Waleed Ahmed Gado, Ahmed Aly Abdelmawla, Mahmoud Abdelnaby, Alaa Magdy
BACKGROUND: The use of synthetic mesh for ventral hernia repair under contaminated conditions is a controversial issue due to the considerable risk of surgical site infection (SSI). This study aimed to review the outcomes of repair of incarcerated and strangulated ventral hernias with or without synthetic mesh in compliance with established clinical guidelines regarding the incidence of SSI and hernia recurrence. METHODS: The records of patients with complicated ventral hernias who were treated with or without synthetic mesh repair were reviewed...
2017: World Journal of Emergency Surgery: WJES
https://www.readbyqxmd.com/read/28721865/eliminating-acute-rheumatic-fever-and-rheumatic-heart-disease
#13
Magdi Yacoub, Bongani Mayosi, Ahmed ElGuindy, Alain Carpentier, Salim Yusuf
No abstract text is available yet for this article.
July 15, 2017: Lancet
https://www.readbyqxmd.com/read/28709382/severe-aortic-valve-stenosis-due-to-alkaptonuric-ochronosis
#14
Magdy El-Sayed Ahmed, Omar Hussain, David A Ott, Muhammad Aftab
Alkaptonuric ochronosis is a rare cause of aortic valve stenosis. We report the case of a 61-year-old female patient with alkaptonuria who presented to our institute with the clinical picture of severe aortic valve stenosis, which was confirmed by transthoracic echocardiography. On aortotomy, she was noted to have an impressive black discoloration of ascending aorta and the aortic root complex involving the aortic valve leaflets. She underwent an uneventful aortic valve replacement. She was discharged home 10 days postoperatively...
July 1, 2017: Seminars in Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28695623/simultaneous-valorization-and-biocatalytic-upgrading-of-heavy-vacuum-gas-oil-by-the-biosurfactant-producing-pseudomonas-aeruginosa-ak6u
#15
Wael Ahmed Ismail, Magdy El-Said Mohamed, Maysoon N Awadh, Christian Obuekwe, Ashraf M El Nayal
Heavy vacuum gas oil (HVGO) is a complex and viscous hydrocarbon stream that is produced as the bottom side product from the vacuum distillation units in petroleum refineries. HVGO is conventionally treated with thermochemical process, which is costly and environmentally polluting. Here, we investigate two petroleum biotechnology applications, namely valorization and bioupgrading, as green approaches for valorization and upgrading of HVGO. The Pseudomonas aeruginosa AK6U strain grew on 20% v/v of HVGO as a sole carbon and sulfur source...
July 11, 2017: Microbial Biotechnology
https://www.readbyqxmd.com/read/28692924/experimental-co-infection-of-infectious-bronchitis-and-low-pathogenic-avian-influenza-h9n2-viruses-in-commercial-broiler-chickens
#16
Kareem E Hassan, Ahmed Ali, Salama A S Shany, Magdy F El-Kady
In this study, commercial broilers were experimentally infected with single (classical IBV, variant IBV or AIV-H9N2) or mixed AIV-H9N2 with classical, variant or vaccine strains of IBV. Birds were monitored for clinical and pathological outcomes and virus shedding for 10days post infection (DPI). Clinical signs were limited to the respiratory tract in all challenged groups and varied from mild to moderate mouth breathing to severe respiratory signs with snorting sound and extended head. Mortalities were only recorded in mixed AIV-H9N2/variant IBV challenge group...
June 30, 2017: Research in Veterinary Science
https://www.readbyqxmd.com/read/28684439/improving-postoperative-outcome-of-congenital-heart-surgery-in-low-middle-income-countries-climbing-mount-excellence
#17
EDITORIAL
Magdi Yacoub, Hatem Hosny, Ahmed Afifi
No abstract text is available yet for this article.
July 6, 2017: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/28677142/assessment-of-sexually-related-personal-distress-accompanying-premenopausal-sexual-dysfunction-with-an-arabic-version-of-the-female-sexual-distress-scale
#18
Magdy R Ahmed, Mohamed M Shaaban, Heba K Meky
OBJECTIVE: To assess sexually related personal distress among premenopausal women with female sexual dysfunction (FSD) via a validated Arabic version of the Female Sexual Distress Scale (FSDS). METHODS: A cross-sectional study was conducted among women attending Suez Canal University Hospital, Egypt, between May 2015 and July 2016. In a pilot study to evaluate test-retest reliability and internal consistency, 42 sexually active premenopausal women (aged ≥20 years) completed the Arabic FSDS at recruitment and 2 weeks later...
July 5, 2017: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/28629768/does-the-duration-of-symptoms-of-anal-fissure-impact-its-response-to-conservative-treatment-a-prospective-cohort-study
#19
Sameh Hany Emile, Hesham Elgendy, Hossam Elfeki, Alaa Magdy, Ahmed Aly Abdelmawla, Mahmoud Abdelnaby, Wael Khafagy
BACKGROUND: Conservative treatment is the first line of treatment for anal fissure. The current study aimed to evaluate the impact of symptom duration on the response of anal fissure to conservative treatment. PATIENTS AND METHODS: This prospective study was conducted on sixty patients with acute or chronic anal fissure who were treated conservatively with bulking agents, Sitz baths, and topical glyceryl trinitrate (GTN) 0.2%. Pain and constipation were assessed prior to treatment and at 6 weeks after therapy using visual analogue scale (VAS) and Wexner constipation score...
June 16, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28623919/effects-of-karela-bitter-melon-momordica-charantia-on-genes-of-lipids-and-carbohydrates-metabolism-in-experimental-hypercholesterolemia-biochemical-molecular-and-histopathological-study
#20
Dalia Yossri Saad, Mohamed Mohamed Soliman, Ahmed A Baiomy, Magdy Hassan Yassin, Hanan Basiouni El-Sawy
BACKGROUND: Hypercholesterolemia is a serious diseases associated with type-2 diabetes, atherosclerosis, cardiovascular disorders and liver diseases. Humans seek for safe herbal medication such as karela (Momordica charantia/bitter melon) to treat such disorders to avoid side effect of pharmacotherapies widely used. METHODS: Forty male Wistar rats were divided into four equal groups; control group with free access to food and water, cholesterol administered group (40 mg/kg BW orally); karela administered group (5 g /kg BW orally) and mixture of cholesterol and karela...
June 17, 2017: BMC Complementary and Alternative Medicine
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