Read by QxMD icon Read


Diego H Cáceres, Juan David Zapata, Sinar D Granada, Luz E Cano, Tonny W Naranjo
BACKGROUND: Colombia currently does not have a specialised service for measuring antifungal levels in serum, which is of prime importance for the proper treatment and correct management of invasive fungal infections. AIMS: To standardise and validate a simple, sensitive, and specific protocol, based on high performance liquid chromatography, complying with the parameters recommended by the Food and Drug Administration, to detect, identify, and quantify serum concentrations of posaconazole...
September 20, 2016: Revista Iberoamericana de Micología
Nitin Mukerji, Kuskoor Seetharam Manjunath Prasad, Simon Tizzard, Farooq Aziz, Anil Varma, Ernest Sinar, Fred Nath, Roger Strachan, Philip Kane, Sean Williamson
No abstract text is available yet for this article.
2016: British Journal of Neurosurgery
T J Awe, K J Peterson, E P Yu, R D McBride, D B Sinars, M R Gomez, C A Jennings, M R Martin, S E Rosenthal, D G Schroen, A B Sefkow, S A Slutz, K Tomlinson, R A Vesey
Enhanced implosion stability has been experimentally demonstrated for magnetically accelerated liners that are coated with 70  μm of dielectric. The dielectric tamps liner-mass redistribution from electrothermal instabilities and also buffers coupling of the drive magnetic field to the magneto-Rayleigh-Taylor instability. A dielectric-coated and axially premagnetized beryllium liner was radiographed at a convergence ratio [CR=Rin,0/Rin(z,t)] of 20, which is the highest CR ever directly observed for a strengthless magnetically driven liner...
February 12, 2016: Physical Review Letters
E C Harding, T Ao, J E Bailey, G Loisel, D B Sinars, M Geissel, G A Rochau, I C Smith
The application of a space-resolving spectrometer to X-ray Thomson Scattering (XRTS) experiments has the potential to advance the study of warm dense matter. This has motivated the design of a spherical crystal spectrometer, which is a doubly focusing geometry with an overall high sensitivity and the capability of providing high-resolution, space-resolved spectra. A detailed analysis of the image fluence and crystal throughput in this geometry is carried out and analytical estimates of these quantities are presented...
April 2015: Review of Scientific Instruments
D C Rovang, D C Lamppa, M E Cuneo, A C Owen, J McKenney, D W Johnson, S Radovich, R J Kaye, R D McBride, C S Alexander, T J Awe, S A Slutz, A B Sefkow, T A Haill, P A Jones, J W Argo, D G Dalton, G K Robertson, E M Waisman, D B Sinars, J Meissner, M Milhous, D N Nguyen, C H Mielke
Sandia has successfully integrated the capability to apply uniform, high magnetic fields (10-30 T) to high energy density experiments on the Z facility. This system uses an 8-mF, 15-kV capacitor bank to drive large-bore (5 cm diameter), high-inductance (1-3 mH) multi-turn, multi-layer electromagnets that slowly magnetize the conductive targets used on Z over several milliseconds (time to peak field of 2-7 ms). This system was commissioned in February 2013 and has been used successfully to magnetize more than 30 experiments up to 10 T that have produced exciting and surprising physics results...
December 2014: Review of Scientific Instruments
P F Schmit, P F Knapp, S B Hansen, M R Gomez, K D Hahn, D B Sinars, K J Peterson, S A Slutz, A B Sefkow, T J Awe, E Harding, C A Jennings, G A Chandler, G W Cooper, M E Cuneo, M Geissel, A J Harvey-Thompson, M C Herrmann, M H Hess, O Johns, D C Lamppa, M R Martin, R D McBride, J L Porter, G K Robertson, G A Rochau, D C Rovang, C L Ruiz, M E Savage, I C Smith, W A Stygar, R A Vesey
Magnetizing the fuel in inertial confinement fusion relaxes ignition requirements by reducing thermal conductivity and changing the physics of burn product confinement. Diagnosing the level of fuel magnetization during burn is critical to understanding target performance in magneto-inertial fusion (MIF) implosions. In pure deuterium fusion plasma, 1.01 MeV tritons are emitted during deuterium-deuterium fusion and can undergo secondary deuterium-tritium reactions before exiting the fuel. Increasing the fuel magnetization elongates the path lengths through the fuel of some of the tritons, enhancing their probability of reaction...
October 10, 2014: Physical Review Letters
M R Gomez, S A Slutz, A B Sefkow, D B Sinars, K D Hahn, S B Hansen, E C Harding, P F Knapp, P F Schmit, C A Jennings, T J Awe, M Geissel, D C Rovang, G A Chandler, G W Cooper, M E Cuneo, A J Harvey-Thompson, M C Herrmann, M H Hess, O Johns, D C Lamppa, M R Martin, R D McBride, K J Peterson, J L Porter, G K Robertson, G A Rochau, C L Ruiz, M E Savage, I C Smith, W A Stygar, R A Vesey
This Letter presents results from the first fully integrated experiments testing the magnetized liner inertial fusion concept [S. A. Slutz et al., Phys. Plasmas 17, 056303 (2010)], in which a cylinder of deuterium gas with a preimposed 10 Taxial magnetic field is heated by Z beamlet, a 2.5 kJ, 1 TW laser, and magnetically imploded by a 19 MA, 100 ns rise time current on the Z facility. Despite a predicted peak implosion velocity of only 70 km = s, the fuel reaches a stagnation temperature of approximately 3 keV, with T(e) ≈ T(i), and produces up to 2 x 10(12) thermonuclear deuterium-deuterium neutrons...
October 10, 2014: Physical Review Letters
Guo-Bin Zhang, Hong-Ying Yi, Ji-Ming Gong
Stresses decouple nitrate assimilation and photosynthesis through stress-initiated nitrate allocation to roots (SINAR), which is mediated by the nitrate transporters NRT1.8 and NRT1.5 and functions to promote stress tolerance. However, how SINAR communicates with the environment remains unknown. Here, we present biochemical and genetic evidence demonstrating that in Arabidopsis thaliana, ethylene (ET) and jasmonic acid (JA) affect the crosstalk between SINAR and the environment. Electrophoretic mobility shift assays and chromatin immunoprecipitation assays showed that ethylene response factors (ERFs), including OCTADECANOID-RESPONSIVE ARABIDOPSIS AP2/ERF59, bind to the GCC boxes in the NRT1...
October 2014: Plant Cell
M C Jones, D J Ampleford, M E Cuneo, R Hohlfelder, C A Jennings, D W Johnson, B Jones, M R Lopez, J MacArthur, J A Mills, T Preston, G A Rochau, M Savage, D Spencer, D B Sinars, J L Porter
Advancements have been made in the diagnostic techniques to measure accurately the total radiated x-ray yield and power from z-pinch implosion experiments at the Z machine with high accuracy. The Z machine is capable of outputting 2 MJ and 330 TW of x-ray yield and power, and accurately measuring these quantities is imperative. We will describe work over the past several years which include the development of new diagnostics, improvements to existing diagnostics, and implementation of automated data analysis routines...
August 2014: Review of Scientific Instruments
Kyle J Peterson, Thomas J Awe, Edmund P Yu, Daniel B Sinars, Ella S Field, Michael E Cuneo, Mark C Herrmann, Mark Savage, Diana Schroen, Kurt Tomlinson, Charles Nakhleh
Recent experiments on Sandia's Z facility have confirmed simulation predictions of dramatically reduced instability growth in solid metallic rods when thick dielectric coatings are used to mitigate density perturbations arising from an electrothermal instability. These results provide further evidence that the inherent surface roughness as a result of target fabrication is not the dominant seed for the growth of magneto-Rayleigh-Taylor instabilities in liners with carefully machined smooth surfaces, but rather electrothermal instabilities that form early in the electrical current pulse as Joule heating melts and vaporizes the liner surface...
April 4, 2014: Physical Review Letters
T J Awe, R D McBride, C A Jennings, D C Lamppa, M R Martin, D C Rovang, S A Slutz, M E Cuneo, A C Owen, D B Sinars, K Tomlinson, M R Gomez, S B Hansen, M C Herrmann, J L McKenney, C Nakhleh, G K Robertson, G A Rochau, M E Savage, D G Schroen, W A Stygar
Novel experimental data are reported that reveal helical instability formation on imploding z-pinch liners that are premagnetized with an axial field. Such instabilities differ dramatically from the mostly azimuthally symmetric instabilities that form on unmagnetized liners. The helical structure persists at nearly constant pitch as the liner implodes. This is surprising since, at the liner surface, the azimuthal drive field presumably dwarfs the axial field for all but the earliest stages of the experiment...
December 6, 2013: Physical Review Letters
K Michele Kacmar, Wayne S Crawford, Dawn S Carlson, Merideth Ferguson, Dwayne Whitten
The stream of research concerning work-family enrichment has generated a significant body of research because it plays an important role in occupational health (Masuda, McNall, Allen, & Nicklin, 2012). work-family enrichment has been defined as "the extent to which experiences in one role improve the quality of life in the other role" (Greenhaus & Powell, 2006, p. 73). Within work-family enrichment, there are two directions: work to family and family to work. Carlson, Kacmar, Wayne, and Grzywacz (2006) developed an 18-item scale to measure this construct...
January 2014: Journal of Occupational Health Psychology
Julie M McCarthy, Chad H Van Iddekinge, Filip Lievens, Mei-Chuan Kung, Evan F Sinar, Michael A Campion
Considerable evidence suggests that how candidates react to selection procedures can affect their test performance and their attitudes toward the hiring organization (e.g., recommending the firm to others). However, very few studies of candidate reactions have examined one of the outcomes organizations care most about: job performance. We attempt to address this gap by developing and testing a conceptual framework that delineates whether and how candidate reactions might influence job performance. We accomplish this objective using data from 4 studies (total N = 6,480), 6 selection procedures (personality tests, job knowledge tests, cognitive ability tests, work samples, situational judgment tests, and a selection inventory), 5 key candidate reactions (anxiety, motivation, belief in tests, self-efficacy, and procedural justice), 2 contexts (industry and education), 3 continents (North America, South America, and Europe), 2 study designs (predictive and concurrent), and 4 occupational areas (medical, sales, customer service, and technological)...
September 2013: Journal of Applied Psychology
Zhen Liu, Xiao-Xia Wan, Xin-Guo Huang, Qiang Liu, Chan Li
The multispectral image acquisition oriented to reproduction requests that the data is device independent and scenes independent, and can realize the characterization of the original color information. Aiming at disturbance, noise error of system, and the requirement for training samples' typical representative and correlation, the authors proposed orthogonal regression spectral algorithm and training samples selection algorithm based on subspace tracking, through the mapping function between the spectral space and color space, by selecting the best samples in typical representative and correlation samples between target samples and selected samples...
April 2013: Guang Pu Xue Yu Guang Pu Fen Xi, Guang Pu
D B Sinars, R D McBride, S A Pikuz, T A Shelkovenko, D F Wenger, M E Cuneo, E P Yu, J P Chittenden, E C Harding, S B Hansen, B P Peyton, D J Ampleford, C A Jennings
Using solid, machined X-pinch targets driven by currents rising from 0 to 5-6 MA in 60 ns, we observed bright spots of 5-9-keV continuum radiation from 5±2-μm diameter regions. The >6-keV radiation is emitted in about 0.4 ns, and the bright spots are roughly 75 times brighter than the bright spots measured at 1 MA. A total x-ray power of 10 TW peak and yields of 165±20 kJ were emitted from a 3-mm height. The 3-5-keV continuum radiation had a 50-90-GW peak power and 0.15-0.35-kJ yield. The continuum is plausibly from a 1275±75-eV blackbody or alternatively from a 3500±500-eV bremsstrahlung source...
October 12, 2012: Physical Review Letters
R D McBride, S A Slutz, C A Jennings, D B Sinars, M E Cuneo, M C Herrmann, R W Lemke, M R Martin, R A Vesey, K J Peterson, A B Sefkow, C Nakhleh, B E Blue, K Killebrew, D Schroen, T J Rogers, A Laspe, M R Lopez, I C Smith, B W Atherton, M Savage, W A Stygar, J L Porter
The implosions of initially solid beryllium liners (tubes) have been imaged with penetrating radiography through to stagnation. These novel radiographic data reveal a high degree of azimuthal correlation in the evolving magneto-Rayleigh-Taylor structure at times just prior to (and during) stagnation, providing stringent constraints on the simulation tools used by the broader high energy density physics and inertial confinement fusion communities. To emphasize this point, comparisons to 2D and 3D radiation magnetohydrodynamics simulations are also presented...
September 28, 2012: Physical Review Letters
M F Hassan, M B Mohamed, P Kalsi, E J Sinar, N Bradey
Primary pyogenic abscess in the conus medullaris in a healthy adult has never been reported. An urgent MRI scan with contrast and prompt surgical evacuation may lead to good neurological recovery.
February 2012: British Journal of Neurosurgery
D B Sinars, D F Wenger, S A Pikuz, B Jones, M Geissel, S B Hansen, C A Coverdale, D J Ampleford, M E Cuneo, L A McPherson, G A Rochau
We describe a pair of time-integrated transmission spectrometers that are designed to survey 7-28 keV (1.9 to 0.43 Å) x-ray photons produced by experiments on the Sandia Z pulsed power facility. Each spectrometer uses a quartz 10-11 crystal in a Cauchois geometry with a slit to provide spatial resolution along one dimension. The spectrometers are located in the harsh environment of the Z vacuum chamber, which necessitates that their design be compact and rugged. Example data from calibration tests and Z experiments are shown that illustrate the utility of the instruments...
June 2011: Review of Scientific Instruments
D B Sinars, S A Slutz, M C Herrmann, R D McBride, M E Cuneo, K J Peterson, R A Vesey, C Nakhleh, B E Blue, K Killebrew, D Schroen, K Tomlinson, A D Edens, M R Lopez, I C Smith, J Shores, V Bigman, G R Bennett, B W Atherton, M Savage, W A Stygar, G T Leifeste, J L Porter
The first controlled experiments measuring the growth of the magneto-Rayleigh-Taylor instability in fast (∼100  ns) Z-pinch plasmas are reported. Sinusoidal perturbations on the surface of an initially solid Al tube (liner) with wavelengths of 25-400  μm were used to seed the instability. Radiographs with 15  μm resolution captured the evolution of the outer liner surface. Comparisons with numerical radiation magnetohydrodynamic simulations show remarkably good agreement down to 50  μm wavelengths...
October 29, 2010: Physical Review Letters
Farid E Ahmed, Clark D Jeffries, Paul W Vos, Gordon Flake, Gerard J Nuovo, Dennis R Sinar, Wade Naziri, Stefan P Marcuard
By routinely and systematically being able to perform quantitative stem-loop reverse transcriptase followed by TaqMan PCR expression analysis on stool and tissue samples using fifteen human (Homo sapiens, hsa) micro(mi)RNA genes selected by careful analysis of the peer-reviewed literature, we were able to monitor changes at various stages of CRC, allowing for reliable diagnostic screening of colon cancer particularly at the early, pre-malignant stages, and for difficult-to-treat active ulcerative colitis (UC)...
September 2009: Cancer Genomics & Proteomics
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"