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https://www.readbyqxmd.com/read/28440419/different-effects-of-%C3%A2-borneol-and-%C3%A2-%C3%A2-borneol-on-the-pharmacokinetics-of-osthole-in-rats-following-oral-administration
#1
Dan-Dan Luo, Xiao-Ying Chen, Zhen-Biao Zhang, Chao-Yue Sun, Yi-Feng Zheng, Yu-Hong Liu, Xiu-Fen Wang, Qi Wang, Janis Ya-Xian Zhan, Zi-Ren Su
Osthole is the primary active component of a number of herbal plants such as the Cnidium monnieri fruit. In traditional Chinese herb medicine, osthole is commonly used in combination with borneol to obtain improved pharmacological effects. The aim of the present study was to investigate the effect of borneol enantiomers on the pharmacokinetics of osthole. An appropriate high‑performance liquid chromatography (HPLC) method was applied to determine the concentrations of osthole in plasma. Following oral administration of osthole alone or combined with borneol in rats, blood samples were collected and analyzed by HPLC...
April 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28439998/the-effects-of-chosen-plant-extracts-and-compounds-on-mesenchymal-stem-cells-a-bridge-between-molecular-nutrition-and-regenerative-medicine-concise-review
#2
REVIEW
Katarzyna Kornicka, Ievgeniia Kocherova, Krzysztof Marycz
Mesenchymal stem cells (MSC) stand as a promising tool in regenerative medicine because of their high therapeutic potential in treatment of degenerative, metabolic and other types of diseases. The cellular therapies involving MSCs include their isolation mainly from the bone marrow, adipose tissue or umbilical cord and in vitro expansion for further autologous or allogeneic transplantation. Recent studies revealed, that bioactive compounds, naturally occurring in seaweeds, herbs, fruits and vegetables, possess the ability to modulate self-renewal and differentiation potential of adult stem cells, targeting a broad range of intracellular signal transduction pathways...
April 25, 2017: Phytotherapy Research: PTR
https://www.readbyqxmd.com/read/28439292/effects-of-bushen-tianjing-recipe-in-a-rat-model-of-tripterygium-glycoside-induced-premature-ovarian-failure
#3
Xiaofeng Xu, Yong Tan, Guorong Jiang, Xuanyi Chen, Rensheng Lai, Lurong Zhang, Guoqiang Liang
BACKGROUND: Bushen Tianjing Recipe (BTR) is a traditional Chinese herbal medicine that has been prescribed for premature ovarian failure (POF) for decades in China. Nevertheless, little is known regarding its underlying molecular mechanism. In the present study, we investigated the effects of BTR in a tripterygium glycoside (TG)-induced-POF rat model. METHODS: Three doses of BTR were administered via intragastric gavage to adult female Sprague-Dawley (SD) rats with TG-induced POF...
2017: Chinese Medicine
https://www.readbyqxmd.com/read/28438745/management-of-chronic-pain-using-complementary-and-integrative-medicine
#4
REVIEW
Lucy Chen, Andreas Michalsen
Complementary and integrative medicine (CIM) encompasses both Western-style medicine and complementary health approaches as a new combined approach to treat a variety of clinical conditions. Chronic pain is the leading indication for use of CIM, and about 33% of adults and 12% of children in the US have used it in this context. Although advances have been made in treatments for chronic pain, it remains inadequately controlled for many people. Adverse effects and complications of analgesic drugs, such as addiction, kidney failure, and gastrointestinal bleeding, also limit their use...
April 24, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28438564/essential-oil-of-artemisia-argyi-suppresses-inflammatory-responses-by-inhibiting-jak-stats-activation
#5
Lin-Lin Chen, Hao-Jun Zhang, Jung Chao, Jun-Feng Liu
ETHNOPHARMACOLOGICAL RELEVANCE: Artemisia argyi is a herbal medicine traditionally used in Asia for the treatment of bronchitis, dermatitis and arthritis. Recent studies revealed the anti-inflammatory effect of essential oil in this plant. However, the mechanisms underlying the therapeutic potential have not been well elucidated. The present study is aimed to verify anti-inflammatory effect and investigate the probable mechanisms. MATERIALS AND METHODS: The essential oil from Artemisia argyi (AAEO) was initially tested against LPS-induced production of inflammatory mediators and cytokines in RAW264...
April 21, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28438278/complementary-and-alternative-medicine-cam-among-australian-hospital-based-nurses-knowledge-attitude-personal-and-professional-use-reasons-for-use-cam-referrals-and-socio-demographic-predictors-of-cam-users
#6
Seyed Afshin Shorofi, Paul Arbon
OBJECTIVE: This study was intended to examine CAM among Australian hospital-based nurses, identifying their knowledge, attitude, personal and professional use, reasons for use, CAM referrals, and socio-demographic predictors of CAM users. METHODS AND MATERIALS: Nurses holding a qualification in nursing and working in surgical wards were included using a convenience sampling technique. A self-complete questionnaire was developed to achieve the aims of the study. Descriptive and non-parametric statistics were calculated to describe and analyse data...
May 2017: Complementary Therapies in Clinical Practice
https://www.readbyqxmd.com/read/28436684/serenoa-repens-for-lower-urinary-tract-symptoms-benign-prostatic-hyperplasia-current-evidence-and-its-clinical-implications-in-naturopathic-medicine
#7
Soo Liang Ooi, Sok Cheon Pak
OBJECTIVES: Benign prostatic hyperplasia (BPH) commonly affects men above 40 years old. The progression of BPH is often accompanied with lower urinary tract symptoms (LUTS) that can significantly affect the quality of life of the patients. Serenoa repens (saw palmetto) is a popular herbal remedy indicated for LUTS/BPH. We reviewed the current research on the efficacy of S. repens on LUTS/BPH as a monotherapy as well as combination therapies. DESIGN: Non-systematic searches were performed in PubMed for human studies and systematic reviews on the topic...
April 24, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/28435373/comparative-clinical-efficacy-of-three-toothpastes-in-the-control-of-supragingival-calculus-formation
#8
Petcharat Kraivaphan, Cholticha Amornchat
OBJECTIVES: The purpose of this double-blind, parallel clinical study was to assess clinical efficacy in supragingival calculus formation reduction using Abhaibhubejhr Herbal Toothpaste compared to Colgate Total and Colgate Cavity Protection toothpastes. MATERIALS AND METHODS: A total of 150 subjects participated in the pretest phase. All subjects were given oral soft/hard tissue evaluation, calculus examination using Volpe-Manhold calculus, and whole mouth oral prophylaxis...
January 2017: European Journal of Dentistry
https://www.readbyqxmd.com/read/28435036/costunolide-increases-osteoblast-differentiation-via-atf4-dependent-ho-1-expression-in-c3h10t1-2-cells
#9
Wan-Jin Jeon, Kyeong-Min Kim, Eun-Jung Kim, Won-Gu Jang
AIMS: Costunolide is a sesquiterpene lactones used in many herbal medicines, with well-established anti-inflammatory and anti-oxidant functions modulating endoplasmic reticulum (ER) stress pathways, and which promotes the expression of anti-oxidant genes. The aim of this study is to investigate whether costunolide is involved in osteoblast differentiation and, determine the mechanisms of differentiation in mesenchymal stem cells. MAIN METHODS: The cytotoxicity of costunolide was identified using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay...
April 20, 2017: Life Sciences
https://www.readbyqxmd.com/read/28434474/chinese-herbal-medicine-adjunct-therapy-in-patients-with-acute-relapse-of-multiple-sclerosis-a-systematic-review-and-meta-analysis
#10
REVIEW
Liang Song, Qi-Hui Zhou, Hui-Lin Wang, Feng-Jiao Liao, Liang Hua, Hong-Feng Zhang, Li-Bo Huang, Yan Lin, Guo-Qing Zheng
BACKGROUND: Many patients with multiple sclerosis (MS) resort to complementary and alternative medicine, which is used in 33%-80% of MS patients in the developed country. The purpose of this study is to assess the efficacy and safety of Chinese herbal medicine (CHM) as an adjunct therapy of patients with acute relapse of MS. METHODS: Six databases were searched for randomized-controlled trial of CHM for acute relapse of MS. The risk of bias was assessed by using the twelve criteria recommended by the Cochrane Back Review Group...
April 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28434468/the-effect-of-chinese-herbal-medicine-banxia-baizhu-tianma-decoction-for-the-treatment-of-vertebrobasilar-insufficiency-vertigo-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#11
REVIEW
ZhenLang Guo, ZhenNing Su, ZhengFei Wang, XiaoMu Luo, RenKui Lai
OBJECTIVES: Banxia Baizhu Tianma Decoction (BBTD) is widely used to treat vertebrobasilar insufficiency vertigo (VBIV) in China, but its efficacy remains largely unexplored. We systemically summarized relevant evidence from randomized controlled trials (RCTs) to assess the therapeutic effect of BBTD. METHODS: Seven electronic databases were searched for relevant electronic studies published before July 2016. We evaluated RCTs that compared BBTD, anti-vertigo drugs and a combination of BBTD and anti-vertigo drugs...
April 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28434181/management-options-for-biochemically-recurrent-prostate-cancer
#12
REVIEW
Farhad Fakhrejahani, Ravi A Madan, William L Dahut
Prostate cancer is the most common solid tumor malignancy in men worldwide. Treatment with surgery and radiation can be curative in organ-confined disease. Unfortunately, about one third of men develop biochemically recurrent disease based only on rising prostate-specific antigen (PSA) in the absence of visible disease on conventional imaging. For these patients with biochemical recurrent prostate cancer, there is no uniform guideline for subsequent management. Based on available data, it seems prudent that biochemical recurrent prostate cancer should initially be evaluated for salvage radiation or prostatectomy, with curative intent...
May 2017: Current Treatment Options in Oncology
https://www.readbyqxmd.com/read/28433747/chemical-composition-of-ocimum-sanctum-by-lc-esi-ms-ms-analysis-and-its-protective-effects-against-smoke-induced-lung-and-neuronal-tissue-damage-in-rats
#13
M P Venuprasad, Hemanth Kumar Kandikattu, Sakina Razack, Narayanappa Amruta, Farhath Khanum
Smoke induced oxidative stress is known to cause various cancers and associated health problems including lung cancer. Herbal extracts have been reported as antioxidant supplements which attenuate free radical induced oxidative damage of tissues, among which Ocimum sanctum has been reported as the elixir of life due to its innumerable health benefits. In the present study, we investigated the protective effect of O. sanctum against cracker smoke induced lung and brain tissue damage. The results of the study demonstrate that O...
April 20, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28433714/effects-of-dietary-supplementation-with-fenugreek-seeds-alone-or-in-combination-with-probiotics-on-gilthead-seabream-sparus-aurata-l-skin-mucosal-immunity
#14
F A Guardiola, A Bahi, A Bakhrouf, M A Esteban
Despite increasing interest in modulating the immune response of fish, providing a combination of probiotics and herbal immunostimulants in aquafeed has rarely has been studied. The effects on gilthead seabream (Sparus aurata L.) of the dietary administration of fenugreek (Trigonella foenum graecum) seeds alone (FE), or combined with one of the following probiotic strains: Bacillus licheniformis (FEBL), Lactobacillus plantarum (FELP) or Bacillus subtilis (FEBS) were evaluated. Fish were fed a control or one of the supplemented diets for 3 weeks...
April 19, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28432819/identification-of-bioactive-compounds-in-shaoyao-gancao-decoction-using-%C3%AE-2-adrenoceptor-affinity-chromatography
#15
Zehua Li, Haiyang Gao, Jiangying Li, Yajun Zhang
Shaoyao-Gancao decoction, a Chinese herbal formula, is composed of Paeoniae Radix alba and Glycyrrhiza Radix et rhizoma. It has been widely used to treat muscle spasms and asthma. However, little is known about the bioactive components of Shaoyao-Gancao decoction. In the present study, the bioactive compounds in water-extract of Shaoyao-Gancao decoction were separated by the immobilized β2 -adrenoceptor affinity column and identified using quadrupole time-of-flight mass spectrometry. The affinity constants of the separated compounds that bound to β2 -adrenoceptor were determined by frontal analysis...
April 22, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28432185/exogenous-cushing-s-syndrome-due-to-a-chinese-herbalist-s-prescription-of-ointment-containing-dexamethasone
#16
Viola Franke, Winnie Francien Scholtens, Ines Alexandra von Rosenstiel, Marie Jose Walenkamp
Eczema in children is a chronic disabling condition. The impact of this condition on the lives of families is often underestimated by conventional physicians. As a consequence parents may investigate complementary treatment options. Close monitoring by a paediatrician is essential, considering that a variety of adverse effects can occur during the use of complementary treatment. We present a 5-year-old girl with eczema. She visited a Chinese herbalist who prescribed an ointment. The parents noticed that the eczema resolved fast, itching decreased and she was finally sleeping well...
April 20, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28431534/the-effects-of-spirulina-platensis-on-anthropometric-indices-appetite-lipid-profile-and-serum-vascular-endothelial-growth-factor-vegf-in-obese-individuals-a-randomized-double-blinded-placebo-controlled-trial
#17
Reihaneh Zeinalian, Mahdieh Abbasalizad Farhangi, Atefeh Shariat, Maryam Saghafi-Asl
BACKGROUND: In recent years, a great attention has been focused on Spirulina platensis as a source of potential valuable nutrients for prevention and treatment of chronic diseases. The objectives of the current study were to determine the effects of Spirulina platensis on anthropometric parameters, serum lipids, appetite and serum Vascular Endothelial Growth Factor (VEGF) in obese individuals. METHODS: In the current study sixty four obese individuals aged 20-50 years were enrolled and randomly allocated into two groups of intervention and placebo...
April 21, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28431028/hybrid-de-novo-genome-assembly-of-the-chinese-herbal-fleabane-erigeron-breviscapus
#18
Jing Yang, Guanghui Zhang, Jing Zhang, Hui Liu, Wei Chen, Xiao Wang, Yahe Li, Yang Dong, Shengchao Yang
Background: The plants in the Erigeron genus of the Compositae (Asteraceae) family are commonly called fleabanes, possibly due to the belief that certain chemicals in these plants repel fleas. In the traditional Chinese medicine, Erigeron breviscapus , which is native to China, was widely used in the treatment of cerebrovascular disease. A handful of bioactive compounds, including scutellarin, 3,5-dicaffeoylquinic acid, and 3,4-dicaffeoylquinic acid, have been isolated from the plant...
April 18, 2017: GigaScience
https://www.readbyqxmd.com/read/28430618/t-2-mycotoxin-toxicological-effects-and-decontamination-strategies
#19
REVIEW
Manish Adhikari, Bhawana Negi, Neha Kaushik, Anupriya Adhikari, Abdulaziz A Al-Khedhairy, Nagendra Kumar Kaushik, Eun Ha Choi
Mycotoxins are highly diverse secondary metabolites produced in nature by a wide variety of fungus which causes food contamination, resulting in mycotoxicosis in animals and humans. In particular, trichothecenes mycotoxin produced by genus fusarium is agriculturally more important worldwide due to the potential health hazards they pose. It is mainly metabolized and eliminated after ingestion, yielding more than 20 metabolites with the hydroxy trichothecenes-2 toxin being the major metabolite. Trichothecene is hazardously intoxicating due to their additional potential to be topically absorbed, and their metabolites affect the gastrointestinal tract, skin, kidney, liver, and immune and hematopoietic progenitor cellular systems...
February 16, 2017: Oncotarget
https://www.readbyqxmd.com/read/28430157/development-of-user-friendly-method-to-distinguish-subspecies-of-the-korean-medicinal-herb-perilla-frutescens-using-multiplex-pcr
#20
Yonguk Kim, Ah-Young Kim, Ara Jo, Hakjoon Choi, Seung-Sik Cho, Chulyung Choi
Perilla (Perilla frutescens) is an economically and culturally important plant in East Asia. Plant breeding between cultivars has enhanced the genetic diversity of perilla overall, but means that functionally diverse subspecies are more difficult to identify and distinguish. In this study, we developed gene-based DNA markers to distinguish between the Korean herbal medicinal perilla varieties. We identified informative simple sequence repeat (SSR) regions on the promoter regions of the Myb-P1 and dihydroflavonol 4-reductase (DFR) genes, as well as a large insertion-deletion (indel) region in the limonene synthase (LS) gene, and developed markers to characterize the distinct subspecies differences (PfMyb-P1pro, PfDFRpro, and PfLS, respectively)...
April 21, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
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