Paolo Meani, Roberto Lorusso, Mariusz Kowalewski, Giuseppe Isgrò, Anna Cazzaniga, Angela Satriano, Alice Ascari, Mattia Bernardinetti, Mauro Cotza, Giuseppe Marchese, Erika Ciotti, Hassan Kandil, Umberto Di Dedda, Tommaso Aloisio, Alessandro Varrica, Alessandro Giamberti, Marco Ranucci
Background: The effectiveness of veno-arterial extracorporeal life support (V-A ECLS) in treating neonatal and pediatric patients with complex congenital heart disease (CHD) and requiring cardio-circulatory assistance is well-known. Nevertheless, the influence of left ventricle (LV) distension and its countermeasure, namely LV unloading, on survival and clinical outcomes in neonates and children treated with V-A ECLS needs still to be addressed. Therefore, the aim of this study was to determine the effects of LV unloading on in-hospital survival and complications in neonates and children treated with V-A ECLS...
2022: Frontiers in Cardiovascular Medicine