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bone marrow edema and reactive arthritis

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https://www.readbyqxmd.com/read/27744396/quantification-of-bone-marrow-edema-by-magnetic-resonance-imaging-only-marginally-reflects-clinical-neck-pain-evaluation-in-rheumatoid-arthritis-and-ankylosing-spondylitis
#1
Xenofon Baraliakos, Frank Heldmann, Johanna Callhoff, Ravi Suppiah, Fiona Marion McQueen, Dietmar Krause, Claudia Klink, Elmar Schmitz-Bortz, Manfred Igelmann, Ludwig Kalthoff, Uta Kiltz, Anna Schmuedderich, Juergen Braun
OBJECTIVE: Neck pain is common in rheumatoid arthritis (RA) and ankylosing spondylitis (AS). We investigated the correlation of bone marrow edema (BME) on magnetic resonance imaging (MRI) in RA and AS and its association with clinical complaints of neck pain. METHODS: Cervical spine short-tau inversion recovery-MRI and T1w-MRI of 34 patients with RA and 6 patients with AS complaining about neck pain were obtained. Clinical and laboratory data were available. BME was scored by 2 blinded readers using a modification of a published score, including various cervical sites...
December 2016: Journal of Rheumatology
https://www.readbyqxmd.com/read/26681230/associations-between-spondyloarthritis-features-and-magnetic-resonance-imaging-findings-a-cross-sectional-analysis-of-1-020-patients-with-persistent-low-back-pain
#2
Bodil Arnbak, Anne Grethe Jurik, Kim Hørslev-Petersen, Oliver Hendricks, Louise Thuesen Hermansen, Anne Gitte Loft, Mikkel Østergaard, Susanne Juhl Pedersen, Anna Zejden, Niels Egund, René Holst, Claus Manniche, Tue Secher Jensen
OBJECTIVE: The Assessment of SpondyloArthritis international Society (ASAS) has previously published criteria for spondyloarthritis (SpA). In the Spines of Southern Denmark cohort, which included patients with persistent low back pain and an unknown proportion of patients with SpA, our objectives were 1) to estimate the prevalence of magnetic resonance imaging (MRI) findings and clinical features included in the ASAS criteria for SpA and 2) to explore the associations between MRI findings and clinical features...
April 2016: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/26562235/high-resolution-us-of-rheumatologic-diseases
#3
REVIEW
Mihra S Taljanovic, David M Melville, Lana H Gimber, Luke R Scalcione, Margaret D Miller, C Kent Kwoh, Andrea S Klauser
For the past 15 years, high-resolution ultrasonography (US) is being routinely and increasingly used for initial evaluation and treatment follow-up of rheumatologic diseases. This imaging technique is performed by using high-frequency linear transducers and has proved to be a powerful diagnostic tool in evaluation of articular erosions, simple and complex joint and bursal effusions, tendon sheath effusions, and synovitis, with results comparable to those of magnetic resonance imaging, excluding detection of bone marrow edema...
November 2015: Radiographics: a Review Publication of the Radiological Society of North America, Inc
https://www.readbyqxmd.com/read/26299443/studies-on-ageing-and-the-severity-of-radiographic-joint-damage-in-rheumatoid-arthritis
#4
Lukas Mangnus, Hanna W van Steenbergen, Elisabet Lindqvist, Elisabeth Brouwer, Monique Reijnierse, Tom W J Huizinga, Peter K Gregersen, Ewa Berglin, Solbritt Rantapää-Dahlqvist, Désirée van der Heijde, Annette H M van der Helm-van Mil
INTRODUCTION: The western population is ageing. It is unknown whether age at diagnosis affects the severity of Rheumatoid Arthritis (RA), we therefore performed the present study. METHOD: 1,875 RA-patients (7,219 radiographs) included in five European and North-American cohorts (Leiden-EAC, Wichita, Umeå, Groningen and Lund) were studied on associations between age at diagnosis and joint damage severity. In 698 Leiden RA-patients with 7-years follow-up it was explored if symptom duration, anti-citrullinated-peptide-antibodies (ACPA), swollen joint count (SJC) and C-reactive-protein (CRP) mediated the association of age with joint damage...
August 24, 2015: Arthritis Research & Therapy
https://www.readbyqxmd.com/read/26245631/-bone-marrow-edema-and-atraumatic-necrosis-of-the-femoral-head-therapy
#5
REVIEW
J Beckmann, A Roth, C Niethard, F Mauch, R Best, U Maus
BACKGROUND: An increase in interstitial bony fluid occurs in bone-marrow edema (BME). The exact pathogenetic processes still remain unknown. BME is an unspecific finding that can occur on its own or accompany multiple diseases and pathologies. GOAL: Literature review and presentation of new guidelines. MATERIAL AND METHODS: This is a narrative literature review followed by current advice for the therapy of atraumatic osteonecrosis of the hip, based on the recently published S3-guidelines for this disease...
September 2015: Der Orthopäde
https://www.readbyqxmd.com/read/25924445/-correlation-of-rankl-opg-dickkopf-1-and-bone-marrow-edema-in-rheumatoid-arthritis-with-the-complaint-of-knee-pain
#6
Min Li, Xiao-hui Wu, Geng Yin, Qi-bing Xie
OBJECTIVE: To investigate the correlation of the receptor activator of nuclear factor kappa-B ligand (RANKL)/serum osteoprotegerin (OPG) system, Dickkopf-1 (DKK-1) and bone marrow edema (BME) in rheumatoid arthritis (RA) with the complaint of knee pain. METHODS: The clinical data of 50 cases of RA with the complaint of knee pain were collected. According to MRI finding, half of them (25 cases) had bone marrow edema (BME). Each patient received the measurement of serum OPG, RANKL, DKK-1, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), anti cyclic citrullinated peptide antibody (CCP), rheumatoid factort(RF)...
March 2015: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/25698366/metaphyseal-osteomyelitis-in-children-how-often-does-mri-documented-joint-effusion-or-epiphyseal-extension-of-edema-indicate-coexisting-septic-arthritis
#7
Erica K Schallert, J Herman Kan, Johanna Monsalve, Wei Zhang, George S Bisset, Scott Rosenfeld
BACKGROUND: Joint effusions identified by MRI may accompany osteomyelitis and determining whether the joint effusion is septic or reactive has important implications on patient care. OBJECTIVE: Determine the incidence of epiphyseal marrow edema, joint effusions, perisynovial edema and epiphyseal non-enhancement in the setting of pediatric metaphyseal osteomyelitis and whether this may be used to predict coexisting septic arthritis. MATERIALS AND METHODS: Following IRB approval, we retrospectively evaluated children who underwent MRI and orthopedic surgical consultation for suspected musculoskeletal infection between January 2011 and September 2013...
July 2015: Pediatric Radiology
https://www.readbyqxmd.com/read/25163742/biomarkers-for-radiographic-progression-in-rheumatoid-arthritis
#8
REVIEW
A Krabben, T W J Huizinga, A H M van der Helm-van Mil
Treatment of patients with rheumatoid arthritis (RA) is rarely personalized, since predictors of disease course are lacking. The severity of RA can be measured objectively by radiographic progression. The most reliable way to measure radiographic progression is in a longitudinal cohort with serial time points, scoring on a quantitative scale, with a validated scoring method and trained readers. Current models used to predict radiographic progression are based on C-reactive protein and anti-citrullinated protein antibodies...
2015: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/25119259/ultrasonography-and-magnetic-resonance-imaging-findings-of-rheumatoid-arthritis-like-arthritis-in-a-patient-with-adult-t-cell-leukemia
#9
Shin-Ya Kawashiri, Hideki Nakamura, Tomoki Origuchi, Kiyoshi Aoyagi, Atsushi Kawakami
A 43-year-old Japanese woman with adult T-cell leukemia (ATL) developed rheumatoid arthritis-like polyarthritis with dermatitis and skin erosion. Her rheumatoid factor and C-reactive protein results were positive. Musculoskeletal ultrasonography showed intra-articular and peritendinous power Doppler signal-positive synovitis. Plain magnetic resonance imaging showed synovitis of the above lesion and remarkable bone marrow edema/osteitis. She was diagnosed as having ATL-associated arthritis based on the invasion of ATL cells by skin biopsy at the arthritis lesion...
August 13, 2014: Modern Rheumatology
https://www.readbyqxmd.com/read/24841232/relevance-of-the-gut-joint-axis-for-the-management-of-spondyloarthritis-in-daily-clinical-practice
#10
REVIEW
Heleen Cypers, Liesbet Van Praet, Gaëlle Varkas, Dirk Elewaut
PURPOSE OF REVIEW: Thirty years ago, the concept of microscopic gut inflammation in spondyloarthritis (SpA) was established. Over the past decade, there has been tremendous progress in the earlier diagnosis of SpA. In addition, it has been suggested that, because of improved hygiene over the past years, exposure to microorganisms has changed, leading to a shift in diseases, for example, a decreased incidence of reactive arthritis. It is therefore necessary to re-establish the role of gut inflammation in SpA...
July 2014: Current Opinion in Rheumatology
https://www.readbyqxmd.com/read/24669889/advantages-of-a-combined-rheumatoid-arthritis-magnetic-resonance-imaging-score-ramris-for-hand-and-feet-does-the-ramris-of-the-hand-alone-underestimate-disease-activity-and-progression
#11
Philipp Sewerin, Christian Buchbender, Stefan Vordenbäumen, Axel Scherer, Falk Miese, Ralph Brinks, Hans-Joerg Wittsack, Sabine Klein, Matthias Schneider, Gerald Antoch, Benedikt Ostendorf
BACKGROUND: To evaluate a combined rheumatoid arthritis magnetic resonance imaging score (RAMRIS) for hand and foot (HaF-score) in rheumatoid arthritis (RA). METHODS: Magnetic resonance imaging (MRI, 0.2 Tesla) of the dominant hand and foot of 26 ACPA positive RA patients before and 6 months after initiation of methotrexate was obtained. RAMRIS of the hand was complemented by corresponding scoring of the foot (MTP I-V; HaF-score). Disease Activity Score 28 (DAS28) and a tender and swollen joint count (JC) of the joints scored in MRI were recorded...
2014: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/24439184/-a-clinical-analysis-of-509-cases-of-sacroiliitis
#12
Yan-yan Wang, Zheng Zhao, Jiang-lin Zhang, Jian Zhu, Li-xia Feng, Feng Huang
OBJECTIVE: To study the clinical features of sacroiliitis and differential diagnosis. METHODS: Totally 509 patients with chief complaints of back pain and diagnosed as sacroiliitis from January 2007 to January in Chinese PLA General Hospital were enrolled. The clinical manifestations, laboratory examinations, imaging and pathological data of the 509 patients were retrospectively analyzed. RESULTS: There were totally 406 male patients and 103 female patients...
November 2013: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
https://www.readbyqxmd.com/read/24281787/-what-is-ascertained-in-the-therapy-of-axial-spondyloarthritis
#13
REVIEW
J Braun, X Baraliakos, F Heldmann, U Kiltz
The new term axial spondyloarthritis (axSpA) includes classic ankylosing spondylitis and non-radiographic (nr-) axSpA. The definition was introduced in 2009 as part of the Assessment of SpondyloArthritis international Society (ASAS) classification criteria for axSpA, where-apart from chronic back pain starting before the age of 45 years and the presence of HLA-B27-magnetic resonance imaging demonstrated bone marrow edema of the sacroiliac joints (osteomyelitis) or structural changes on x-rays may play an important role...
December 2013: Der Internist
https://www.readbyqxmd.com/read/23807884/diagnostic-imaging-of-sacroiliac-joints-and-the-spine-in-the-course-of-spondyloarthropathies
#14
Iwona Sudoł-Szopinska, Andrzej Urbanik
Spondyloarthropathies belong to a group of rheumatic diseases, in which inflammatory changes affect mainly the sacroiliac joints, spine, peripheral joints, tendon, ligaments and capsule attachments (entheses). This group includes 6 entities: ankylosing spondylitis, arthritis associated with inflammatory bowel disease, reactive arthritis, undifferentiated spondyloarthropathy, psoriatic arthritis and juvenile spondyloarthropathy. In 2009, ASAS (Assessment in SpondyloArthritis international Society) association, published classification criteria for spondyloarthropathies, which propose standardization of clinical-diagnostic approach in the case of sacroiliitis, spondylitis and arthritis...
April 2013: Polish Journal of Radiology
https://www.readbyqxmd.com/read/23334211/mri-of-hand-and-foot-joints-of-patients-with-anticitrullinated-peptide-antibody-positive-arthralgia-without-clinical-arthritis
#15
Annemarie Krabben, Wouter Stomp, Désirée M F M van der Heijde, Jessica A B van Nies, Johan L Bloem, Tom W J Huizinga, Monique Reijnierse, Annette H M van der Helm-van Mil
BACKGROUND: Anticitrullinated peptide antibodies (ACPA) and acute phase reactants may be increased before arthritis becomes clinically detectable, suggesting that the processes underlying rheumatoid arthritis (RA) start preclinically. Whether local inflammation occurs in the preclinical phase is unknown. Therefore, we studied the small joints of ACPA positive arthralgia patients for local subclinical inflammation. METHODS: Imaging was performed using 1.5 T extremity MRI...
September 1, 2013: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/21342915/zoledronic-acid-does-not-reduce-mri-erosive-progression-in-psa-but-may-suppress-bone-oedema-the-zoledronic-acid-in-psoriatic-arthritis-zapa-study
#16
RANDOMIZED CONTROLLED TRIAL
Fiona McQueen, Richard Lloyd, Anthony Doyle, Elizabeth Robinson, Maria Lobo, Melissa Exeter, William J Taylor, Peter Jones, Ian R Reid, Nicola Dalbeth
BACKGROUND: The effect of zoledronic acid (ZA) on articular bone in patients with psoriatic arthritis (PsA) was investigated using MRI. METHODS: Patients with erosive PsA were randomised to receive 3-monthly infusions of ZA or placebo for 1 year. An additional 'tests alone' group received no infusions. Clinical assessments and MRI scans were performed at baseline and 1 year. RESULTS: Paired 1.5T MRI scans were available in 22 patients including 6 who received ZA and 16 who did not (non-ZA = 6 placebo + 10 'tests alone' patients)...
June 2011: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/21211324/-evaluation-of-mri-in-the-diagnosis-of-rheumatoid-arthritis
#17
Ding Song, Bo Liu, Ping Li, Li-Qi Bi
OBJECTIVE: to study the features of rheumatoid arthritis (RA) on MRI of hands and wrists and compare MRI with clinical manifestations and laboratory tests of RA. METHODS: a total of 25 patients fulfilling the 2009 ACR/EULAR RA criteria were enrolled. MRI and plain films of hands and wrists and clinical data of swollen joints, tender joints, visual scale (VAS) score, DAS28 score, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), RF classification, anti-cyclic citrullinated peptide antibodies (anti-CCP antibodies) were obtained simultaneously...
November 23, 2010: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/20812156/-arthritis-of-the-atlanto-axial-joint-with-inflammatory-neck-pain-as-a-primary-manifestation-of-seronegative-rheumatoid-arthritis
#18
U Haeusler, F Dybowski, T A Wittkaemper, K Kisters, G Godolias, J Braun
HISTORY AND ADMISSION FINDINGS: A 68-year-old woman with known degenerative joint disease suffered from increasing neck pain. Physical examination revealed painfully restricted movement of the cervical spine. INVESTIGATIONS: Erythrocyte sedimentation rate and C-reactive protein were increased. Tests for rheumatoid factors, antinuclear, anti-citrullinated protein and anti-neutrophil cytoplasmic antibody were negative. Cervical spine x-ray showed osteochondrosis with partially bridging spondylosis at C5/C6, but there was no atlanto-axial dislocation...
September 2010: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/20810395/mri-in-early-rheumatoid-arthritis-synovitis-and-bone-marrow-oedema-are-independent-predictors-of-subsequent-radiographic-progression
#19
Pernille Bøyesen, Espen A Haavardsholm, Mikkel Ostergaard, Désirée van der Heijde, Sølve Sesseng, Tore K Kvien
OBJECTIVES: To determine whether MRI and conventional (clinical and laboratory) measures of inflammation can predict 3-year radiographic changes measured by the van der Heijde Sharp score in patients with early rheumatoid arthritis (RA). METHODS: 55 patients with RA with disease duration <1 year participated in this 3-year follow-up study. Patients were evaluated at baseline, 3, 6, 12 and 36 months by swollen and tender joint count, disease activity score based on 28-joint count, erythrocyte sedimentation rate (ESR), C reactive protein, MRI measures of synovitis, bone marrow oedema and tenosynovitis of the dominant wrist, as well as conventional x-rays of the hands and wrists...
March 2011: Annals of the Rheumatic Diseases
https://www.readbyqxmd.com/read/20551102/enthesitis-and-related-changes-in-the-knees-in-seronegative-spondyloarthropathies-and-skin-psoriasis-magnetic-resonance-imaging-case-control-study
#20
Yasser Emad, Yasser Ragab, Iman Bassyouni, Omar Moawayh, Magdy Fawzy, Ahmed Saad, Alaa Abou-Zeid, Johannes J Rasker
OBJECTIVE: To describe enhanced magnetic resonance imaging (MRI) features and characteristic entheseal changes in the knees in patients with seronegative spondyloarthropathy (SpA). METHODS: The 56 patients included 30 with psoriatic arthritis, 5 with ankylosing spondylitis, 5 with reactive arthritis, 5 with ulcerative colitis (UC), 5 with Crohn's disease, and another 6 with skin psoriasis. Controls were 20 healthy subjects without knee complaints. MRI was performed in all participants, emphasizing entheseal sites...
August 1, 2010: Journal of Rheumatology
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