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https://www.readbyqxmd.com/read/30429111/an-interpretable-and-expandable-deep-learning-diagnostic-system-for-multiple-ocular-diseases-qualitative-study
#1
Kai Zhang, Xiyang Liu, Fan Liu, Lin He, Lei Zhang, Yahan Yang, Wangting Li, Shuai Wang, Lin Liu, Zhenzhen Liu, Xiaohang Wu, Haotian Lin
BACKGROUND: Although artificial intelligence performs promisingly in medicine, few automatic disease diagnosis platforms can clearly explain why a specific medical decision is made. OBJECTIVE: We aimed to devise and develop an interpretable and expandable diagnosis framework for automatically diagnosing multiple ocular diseases and providing treatment recommendations for the particular illness of a specific patient. METHODS: As the diagnosis of ocular diseases highly depends on observing medical images, we chose ophthalmic images as research material...
November 14, 2018: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/30418332/the-international-multiple-sclerosis-visual-system-consortium-advancing-visual-system-research-in-multiple-sclerosis
#2
Laura J Balcer, Lisanne J Balk, Alexander U Brandt, Peter A Calabresi, Elena H Martinez-Lapiscina, Rachel C Nolan, Friedemann Paul, Axel Petzold, Shiv Saidha
BACKGROUND: The International Multiple Sclerosis Visual System Consortium (IMSVISUAL) was formed in November 2014 with the primary goal of improving research, care, and education regarding the role of the visual system in multiple sclerosis (MS) and related disorders. METHODS: In this review, we describe the formation, goals, activities, and structure of IMSVISUAL, as well as the relationship of IMSVISUAL with the Americas Committee for Treatment and Research in MS (ACTRIMS)...
December 2018: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/30418296/surgical-factors-affecting-changes-in-ocular-surface-dynamics-in-the-early-postoperative-period-after-25-gauge-vitrectomy
#3
Tatsuhiko Sato, Shizuka Koh, Yu-Ichi Yasukura, Masanori Kanai, Yumi Noguchi, Vishal Jhanji, Kohji Nishida
OBJECTIVES: Because vitrectomy-associated postoperative ocular surface changes are not well known, we evaluated such changes before and after vitrectomy in eyes with posterior segment diseases and investigated their associations with patients' characteristics and surgical procedures. METHODS: Thirty-five eyes of 32 consecutive patients (16 women; average age 66.6±11.1 years) were included in this prospective, noncomparative case series from tertiary care university hospital...
November 7, 2018: Eye & Contact Lens
https://www.readbyqxmd.com/read/30418273/cross-country-transportation-efficacy-and-clinical-outcomes-of-preloaded-large-diameter-ultra-thin-descemet-stripping-automated-endothelial-keratoplasty-grafts
#4
Mohit Parekh, Alessandro Ruzza, Bernhard Steger, Colin E Willoughby, Salwah Rehman, Stefano Ferrari, Diego Ponzin, Stephen B Kaye, Vito Romano
PURPOSE: To evaluate the clinical outcomes of preloaded large-diameter ultra-thin grafts for Descemet stripping automated endothelial keratoplasty (UT-DSAEK) after cross-country shipment. METHODS: A laboratory study in an eye bank and a clinical cohort study in an academic tertiary care center were performed. UT-DSAEK (9.5 mm diameter) grafts (n = 7) were prepared, loaded into a commercial device (iGlide; Eurobio, Les Ulis, France), preserved for 4 days at room temperature in transport medium, and analyzed...
October 5, 2018: Cornea
https://www.readbyqxmd.com/read/30417853/evaluation-of-content-and-cost-of-traditional-eye-medication-in-a-resource-poor-country-implications-for-eye-care-practice-and-policy
#5
A E Aghaji, I V Ezeome, E R Ezeome
Background: Cataract, glaucoma, and conjunctivitis are common causes of ocular morbidity in Nigeria. A major obstacle in reducing the burden of ocular morbidity in rural areas is access to eye care services. Up to 80% of the population in developing countries use traditional medications for their primary healthcare needs because they are accessible, available, and affordable. The aim of this study is to evaluate the content and cost of commercialized traditional medications used in the treatment of common eye conditions in Nigeria...
November 2018: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/30415882/-trained-eye-vs-gold-standard
#6
M Molina Anguita, F Abadín López, L Márquez Quero, A M Merino González, M J Salve Diaz Miguel
OBJECTIVE: To determine the degree of correlation between the clinical diagnosis prior to the minor surgery process and its concordance with the results of histopathology report, as well as to determine the surgical data of little clinical importance compared to that which is really necessary and cost-effective. MATERIAL AND METHOD: A descriptive, observational, retrospective and transversal study was conducted of the Minor Surgery Activities of a clinic in the Ciudad Real Health Centre I...
November 8, 2018: Semergen
https://www.readbyqxmd.com/read/30410305/amniotic-membrane-transplantation-with-or-without-autologous-cultivated-limbal-stem-cell-transplantation-for-the-management-of-partial-limbal-stem-cell-deficiency
#7
Namrata Sharma, Sujata Mohanty, Vishal Jhanji, Rasik B Vajpayee
Purpose: To compare the outcomes of amniotic membrane transplantation (AMT) vs cultivated limbal stem cell transplantation (LSCT) in eyes with partial limbal stem cell deficiency (LSCD) following chemical burns. Methods: Eyes with unilateral partial LSCD (#180° involvement) were randomized in two groups to undergo either pannus resection combined with AMT or pannus resection combined with LSCT in a tertiary eye care hospital. Primary outcome measures were time to corneal epithelialization and absence of conjunctivalization of the cornea...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/30407992/the-incidence-of-lacrimal-drainage-disorders-across-a-tertiary-eye-care-network-customization-of-an-indigenously-developed-electronic-medical-record-system-eyesmart
#8
Anthony Vipin Das, Suryasnata Rath, Milind N Naik, Mohammad Javed Ali
PURPOSE: To assess the incidence of lacrimal drainage disorders across a tertiary eye care network in India. METHODS: A 5-year retrospective review of all the patients who were diagnosed with lacrimal drainage disorders across the tertiary care network of L.V. Prasad Eye Institute was performed from January 2013 to December 2017. All the patient data were retrieved using all the diagnostic terms assigned to the lacrimal drainage disorders in the in-house electronic medical record system eyeSmart...
November 5, 2018: Ophthalmic Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/30404085/redesigning-skin-cancer-early-detection-and-care-using-a-new-mobile-health-application-protocol-of-the-skin-research-project-a-randomised-controlled-trial
#9
Monika Janda, Caitlin Horsham, Uyen Koh, Nicole Gillespie, Lois J Loescher, Dimitrios Vagenas, H Peter Soyer
Patients often detect melanoma themselves; therefore, regular skin self-examinations (SSEs) play an important role in the early detection and prompt treatment of melanoma. Mobile teledermoscopy is a technology that may facilitate consumer SSEs and rapid communication with a dermatologist. This paper describes the planned randomised controlled trial of an intervention to determine whether mobile technologies can help improve the precision of SSE in consumers. A randomised controlled trial will be conducted to evaluate mobile teledermoscopy-enhanced SSE versus naked-eye SSE...
November 7, 2018: Dermatology: International Journal for Clinical and Investigative Dermatology
https://www.readbyqxmd.com/read/30389372/incorporating-optical-coherence-tomography-in-the-cataract-preoperative-armamentarium-additional-need-or-additional-burden
#10
Aditya Sudhalkar, Viraj Vasavada, Deepak Bhojwani, C V Gopal Raju, P Vasudev, Shraddha Jain, Mamidipudi R Praveen
PURPOSE: To determine the usefulness of preoperative OCT examination to detect asymptomatic macular abnormalities in patients scheduled for cataract surgery METHODS: Design: Prospective, interventional case series Setting: Iladevi Cataract and Visakha Eye Center, Ahmedabad, IndiaStudy Population: Patients undergoing cataract surgery and intraocular lens(IOL) implantation for senile cataracts. Preoperatively no retinal/macular pathology was identified on clinical evaluation. INTERVENTION: All eyes underwent Macular 5-Line Raster evaluation using Spectral Domain OCT before and after cataract surgery(monthly for 3 months)...
October 30, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/30389250/clinical-evaluation-of-an-automated-subjective-refraction-method-implemented-in-a-computer-controlled-motorized-phoropter
#11
Carles Otero, Mikel Aldaba, Jaume Pujol
PURPOSE: To investigate a new algorithm to perform an automated non-cycloplegic refraction in adults. METHODS: Fifty healthy subjects were measured twice (test-retest) with the new automated subjective refraction method and with the conventional clinician subjective refraction procedure. Objective refraction was also measured with the Grand Seiko WAM-5500 autorefractor. The new automated method was inspired on the root finding bisection algorithm and on the Euclidean distances in the power vector domain...
October 30, 2018: Journal of Optometry
https://www.readbyqxmd.com/read/30388172/factors-influencing-patient-adherence-with-diabetic-eye-screening-in-rural-communities-a-qualitative-study
#12
Yao Liu, Nicholas J Zupan, Olayinka O Shiyanbola, Rebecca Swearingen, Julia N Carlson, Nora A Jacobson, Jane E Mahoney, Ronald Klein, Timothy D Bjelland, Maureen A Smith
OBJECTIVE: Diabetic retinopathy remains the leading cause of blindness among working-age U.S. adults largely due to low screening rates. Rural populations face particularly greater challenges to screening because they are older, poorer, less insured, and less likely to receive guideline-concordant care than those in urban areas. Current patient education efforts may not fully address multiple barriers to screening faced by rural patients. We sought to characterize contextual factors affecting rural patient adherence with diabetic eye screening guidelines...
2018: PloS One
https://www.readbyqxmd.com/read/30385435/trainee-led-versus-specialist-led-management-of-neovascular-age-related-macular-degeneration-a-registry-based-study
#13
Rohan W Essex, Vuong Nguyen, Vincent Daien, Sarah Steinmann, Richard Walton, Mark C Gillies, Daniel Barthelmes
OBJECTIVE: To compare the outcomes of trainee-led and specialist-led management of neovascular age-related macular degeneration. DESIGN: Prospective multicentre registry-based observational study. SETTING: Ophthalmology training centres in Australia and Europe where both trainee-led and specialist-led models of care coexist. PARTICIPANTS: Treatment-naïve eyes with neovascular age-related macular degeneration and at least 12 months follow-up...
November 1, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30384855/risk-prediction-tool-for-use-and-predictors-of-duration-of-postoperative-oxygen-therapy-in-children-undergoing-non-cardiac-surgery-a-case-control-study
#14
Maliwan Oofuvong, Siriwimol Ratprasert, Thavat Chanchayanon
BACKGROUND: We aimed to construct a prediction tool for postoperative oxygen therapy and determine predictors of duration of use among children undergoing non-cardiac surgery. METHODS: Data from this case-control study was obtained from a database of 9820 children aged < 15 years who underwent general anesthesia between January 2010 and December 2013 at a tertiary care hospital in southern Thailand. The primary outcomes were the use and duration (hours) of postoperative oxygen therapy (cases)...
November 2, 2018: BMC Anesthesiology
https://www.readbyqxmd.com/read/30361278/artificial-intelligence-and-deep-learning-in-ophthalmology
#15
Daniel Shu Wei Ting, Louis R Pasquale, Lily Peng, John Peter Campbell, Aaron Y Lee, Rajiv Raman, Gavin Siew Wei Tan, Leopold Schmetterer, Pearse A Keane, Tien Yin Wong
Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc, macular oedema and age-related macular degeneration...
October 25, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30353628/assessment-of-macular-ganglion-cell-complex-using-optical-coherence-tomography-impact-of-a-paediatric-reference-database-in-clinical-practice
#16
Alicia Muñoz-Gallego, Javier De la Cruz, Martín Rodríguez-Salgado, José L Torres-Peña, Javier Sambricio, Ana Ortueta-Olartecoechea, Pilar Tejada-Palacios
IMPORTANCE: Optical coherence tomography software classifies abnormality of macular ganglion cell-inner plexiform layer thickness and macular retinal nerve fibre layer thickness based on adult series. BACKGROUND: We assessed the impact of using paediatric reference macular ganglion cell complex values instead of adult reference values. DESIGN: Cross-sectional study. Primary and tertiary health-care setting. PARTICIPANTS: Out of 140 healthy participants aged 5 to 18 years, 90% were eligible...
October 24, 2018: Clinical & Experimental Ophthalmology
https://www.readbyqxmd.com/read/30340718/prospective-analysis-of-emergency-ophthalmic-referrals-in-a-canadian-tertiary-teaching-hospital
#17
Gavin Docherty, Jiyoung Hwang, Michelle Yang, Brennan Eadie, Kathryn Clapson, Jodi Siever, Simon J Warner
OBJECTIVE: This study was conducted to analyze data from emergency ophthalmology referrals after hours from different hospitals to identify the most common pathologies and compare accuracy of diagnoses. Additionally, examination findings, including visual acuity (VA), intraocular pressure (IOP), and pupils from referring service and ophthalmic examination, were compared to assess agreement. DESIGN: This was a prospective study that reviewed information collected from referring services to the emergency on-call ophthalmology service and compared it with ophthalmic examination between February 2017 and July 2017...
October 2018: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/30321739/development-and-validation-of-a-virtual-agent-to-screen-tobacco-and-alcohol-use-disorders
#18
Marc Auriacombe, Sarah Moriceau, Fuschia Serre, Cécile Denis, Jean-Arthur Micoulaud-Franchi, Etienne de Sevin, Emilien Bonhomme, Stéphanie Bioulac, Mélina Fatseas, Pierre Philip
BACKGROUND: Substance use disorders are under-detected and not systematically diagnosed or screened for by primary care. In this study, we present the acceptability and validity of an Embodied Conversational Agent (ECA) designed to screen tobacco and alcohol use disorder, in individuals who did not seek medical help for these disorders. METHODS: Individuals were included from June 2016 to May 2017 in the Outpatient Sleep Clinic of the University Hospital of Bordeaux...
October 6, 2018: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/30315130/refractive-error-and-visual-impairment-in-ireland-schoolchildren
#19
Siofra Christine Harrington, Jim Stack, Kathryn Saunders, Veronica O'Dwyer
AIM: To report refractive error prevalence and visual impairment in Republic of Ireland (henceforth 'Ireland') schoolchildren. METHODS: The Ireland Eye Study examined 1626 participants (881 boys, 745 girls) in two age groups, 6-7 years (728) and 12-13 years (898), in Ireland between June 2016 and January 2018. Participating schools were selected by stratified random sampling, representing a mix of school type (primary/postprimary), location (urban/rural) and socioeconomic status (disadvantaged/advantaged)...
October 12, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/30289823/prosthetic-replacement-of-the-ocular-surface-ecosystem-prose-versus-standard-of-care-for-postsurgical-lagophthalmos-and-exposure-keratopathy-trends-in-visual-outcomes
#20
Kalla A Gervasio, Kyle J Godfrey, Elizabeth D Marlow, Michelle N Lee, Gary J Lelli
PURPOSE: To compare baseline characteristics and visual acuity outcomes in patients treated with prosthetic replacement of the ocular surface ecosystem (PROSE) versus other standard-of-care (SOC) treatments for postsurgical lagophthalmos and exposure keratopathy. METHODS: An institutional review board-approved, retrospective cohort study of 45 consecutive patients (53 eyes) with postsurgical lagophthalmos and exposure keratopathy following oculoplastic or skull base surgeries treated between August 2011 and August 2017 was performed...
September 27, 2018: Ophthalmic Plastic and Reconstructive Surgery
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