keyword
MENU ▼
Read by QxMD icon Read
search

clinical micro review

keyword
https://www.readbyqxmd.com/read/28720368/a-critical-review-of-miniaturised-percutaneous-nephrolithotomy-is-smaller-better
#1
REVIEW
Silvia Proietti, Guido Giusti, Mahesh Desai, Arvind P Ganpule
CONTEXT: In an effort to reduce morbidity related to percutaneous nephrolithotomy (PCNL), some investigators have progressively introduced miniaturised approaches. The development of miniaturised nephroscopes facilitated widespread dissemination of these techniques and a significant expansion of the role of PCNL in endourology. OBJECTIVE: To discuss the different techniques comprising modern PCNL and identify the pros and cons of each of them. EVIDENCE ACQUISITION: Data for this review were identified through a search of PubMed, including studies published in the last 20 yr in core clinical journals in English...
February 2017: European Urology Focus
https://www.readbyqxmd.com/read/28719818/insights-into-the-unique-functionality-of-inorganic-micro-nanoparticles-for-versatile-ultrasound-theranostics
#2
REVIEW
Xiaoqin Qian, Xiaoxia Han, Yu Chen
The clinical ultrasound (US)-based theranostic biomedicine suffers from the critical issue that traditional microbubbles (MBs) have lots of drawbacks such as low stability, large particle size, difficult structural control, etc. The unique composition, structure and functionality of inorganic micro/nanoplatforms have shown their great prospect for solving these critical issues and drawbacks of traditional organic MBs. This review summarizes and discusses the state-of-art development on exploring inorganic micro/nanoparticles for versatile US-based biomedical applications, ranging from US imaging, photoacoustic imaging, sonodynamic therapy, high intensity-focused US ablation and US-triggered chemotherapy...
July 11, 2017: Biomaterials
https://www.readbyqxmd.com/read/28714778/how-clients-change-emotion-with-emotion-a-programme-of-research-on-emotional-processing
#3
Antonio Pascual-Leone
This paper reviews a body of research that has examined Pascual-Leone and Greenberg's sequential model of emotional processing or used its accompanying measure (the Classification of Affective Meaning States). Research from 24 studies using a plurality of methods examined process-outcome relationships from micro to macro levels of observation and builds support for emotional transformation as a possible causal mechanism of change in psychotherapy. A pooled sample of 310 clinical and 130 sub-clinical cases have been studied, reflecting the process of 7 different treatment approaches in addressing over 5 different presenting clinical problems (including depression, anxiety, relational trauma, and personality disorders)...
July 17, 2017: Psychotherapy Research: Journal of the Society for Psychotherapy Research
https://www.readbyqxmd.com/read/28706912/diagnosis-and-prognosis-review-of-biomarkers-for-mesothelioma
#4
REVIEW
Huan H Sun, Allen Vaynblat, Harvey I Pass
Malignant pleural mesothelioma (MPM) is an aggressive disease arising in pleural cell lining and is associated with asbestos exposure. Today, there is a rising incidence of MPM reaching 3,000 annual cases nationally, primarily from the large population occupationally exposed to asbestos between 1940 and 1980. With a prolonged latency period, presenting clinically 10 to 40 years after exposure, MPM is often diagnosed in late stages and presents median survival time of less than 12 months. There is a serious need for improvement in prognostic and diagnostic tools for MPM...
June 2017: Annals of Translational Medicine
https://www.readbyqxmd.com/read/28705470/hypoxia-and-hypoxia-response-associated-molecular-markers-in-esophageal-cancer-a-systematic-review
#5
REVIEW
Jurgen Peerlings, Lien Van De Voorde, Cristina Mitea, Ruben Larue, Ala Yaromina, Sebastian Sandeleanu, Linda Spiegelberg, Ludwig Dubois, Philippe Lambin, Felix M Mottaghy
PURPOSE: In this systematic review, the existing evidence of available hypoxia-associated molecular response biomarkers in esophageal cancer (EC) patients is summarized and set into the context of the role of hypoxia in the prediction of esophageal cancer, treatment response and treatment outcome. METHODS: A systematic literature search was performed in Web of Science, MEDLINE, and PubMed databases using the keywords: hypoxia, esophagus, cancer, treatment outcome and treatment response...
July 10, 2017: Methods: a Companion to Methods in Enzymology
https://www.readbyqxmd.com/read/28703277/mirnas-and-ovarian-cancer-an-overview
#6
REVIEW
Bornali Deb, Arif Uddin, Supriyo Chakraborty
Ovarian cancer (OC) is the sixth most common cancer in women globally. However, even with the advances in detection andtherapeutics it still represents the most dangerous gynecologic malignancy in women of the industrialized countries. The discovery of micro- RNAs (miRNA), a small noncoding RNA molecule targeting multiple mRNAs and regulation of gene expression by triggering translation repression and/or RNA degradation, has revealed the existence of a new array for regulation of genes involved in cancer. This review summarizes the current knowledge regarding the role of miRNAs expression in OC...
July 13, 2017: Journal of Cellular Physiology
https://www.readbyqxmd.com/read/28700086/antiseptics-for-burns
#7
REVIEW
Gill Norman, Janice Christie, Zhenmi Liu, Maggie J Westby, Jayne M Jefferies, Thomas Hudson, Jacky Edwards, Devi Prasad Mohapatra, Ibrahim A Hassan, Jo C Dumville
BACKGROUND: Burn wounds cause high levels of morbidity and mortality worldwide. People with burns are particularly vulnerable to infections; over 75% of all burn deaths (after initial resuscitation) result from infection. Antiseptics are topical agents that act to prevent growth of micro-organisms. A wide range are used with the intention of preventing infection and promoting healing of burn wounds. OBJECTIVES: To assess the effects and safety of antiseptics for the treatment of burns in any care setting...
July 12, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28689208/staging-with-unilateral-salpingo-oophorectomy-and-expert-pathological-review-result-in-no-recurrences-in-a-series-of-81-intestinal-type-mucinous-borderline-ovarian-tumors
#8
Kobe Dewilde, Philippe Moerman, Karin Leunen, Frederic Amant, Patrick Neven, Ignace Vergote
OBJECTIVE: Recent studies suggest that mucinous borderline ovarian tumors (MBOTs) belong to a high-risk group that is more likely to develop an invasive recurrence. The objective is to determine these risk factors. METHODS: A monocentric retrospective review of all consecutive patients with intestinal-type MBOT diagnosed between 1993 and 2013. All tumors were evaluated by one pathologist without knowledge of clinical outcome. Extensive surgical staging and pathological tumor sampling (1 block/cm diameter in tumors <10 cm and 2 blocks/cm diameter in tumors >10 cm) were performed in all cases...
July 8, 2017: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/28688779/formulation-stabilisation-and-encapsulation-of-bacteriophage-for-phage-therapy
#9
REVIEW
Danish J Malik, Ilya J Sokolov, Gurinder K Vinner, Francesco Mancuso, Salvatore Cinquerrui, Goran T Vladisavljevic, Martha R J Clokie, Natalie J Garton, Andrew G F Stapley, Anna Kirpichnikova
Against a backdrop of global antibiotic resistance and increasing awareness of the importance of the human microbiota, there has been resurgent interest in the potential use of bacteriophages for therapeutic purposes, known as phage therapy. A number of phage therapy phase I and II clinical trials have concluded, and shown phages don't present significant adverse safety concerns. These clinical trials used simple phage suspensions without any formulation and phage stability was of secondary concern. Phages have a limited stability in solution, and undergo a significant drop in phage titre during processing and storage which is unacceptable if phages are to become regulated pharmaceuticals, where stable dosage and well defined pharmacokinetics and pharmacodynamics are de rigueur...
May 14, 2017: Advances in Colloid and Interface Science
https://www.readbyqxmd.com/read/28685379/transcatheter-arterial-embolization-for-renal-angiomyolipoma-using-a-micro-balloon-catheter-and-a-mixture-of-ethanol-and-lipiodol
#10
Yusuke Sawada, Masashi Shimohira, Takuya Hashizume, Ryoji Sobue, Soichiro Mori, Motoo Nakagawa, Yoshiyuki Ozawa, Taku Naiki, Takashi Nagai, Takahiro Yasui, Yuta Shibamoto
PURPOSE: To evaluate the efficacy and safety of transcatheter arterial embolization (TAE) for renal angiomyolipoma (AML) using a micro-balloon catheter and a mixture of ethanol and lipiodol. MATERIALS AND METHODS: Twelve consecutive patients with 15 AMLs, 9 females and 3 males, with a median age of 44 years (range, 11-81), underwent this procedure between 2011 and 2016. In all procedures, a micro-balloon catheter was advanced to the feeding artery of the AML and TAE was performed with a mixture of ethanol and lipiodol under balloon inflation...
July 6, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28676439/the-effect-of-stress-fracture-interventions-in-a-single-elite-infantry-training-unit-1983-2015
#11
Charles Milgrom, Aharon S Finestone
Stress fractures can be seen as an undesired byproduct of demanding physical training. The threshold value of stress that places an individual bone at high risk for stress fracture has not been identified. In a prospective study of stress fractures in 1983, a 31% incidence was found during demanding Israeli infantry basic training by bone scan criteria. Within a subgroup of these recruits, an elite infantry unit was found to have a 40% incidence. Since then and until 2015, eight additional induction companies of the same elite infantry unit were prospectively monitored for stress fractures during their basic training...
July 1, 2017: Bone
https://www.readbyqxmd.com/read/28676000/urinary-bone-turnover-markers-as-target-indicators-for-monitoring-bisphosphonate-drug-treatment-in-the-management-of-osteoporosis
#12
Sohyea Kwon, Anne Wang, Cheryl Sadowski, Nese Yuksel, Michael Roman Doschak
Osteoporosis is a debilitating disease characterized by bone micro-architecture degradation contributing to fragility fractures. Currently, determining bone mineral density (BMD) via dual-energy X-ray absorptiometry (DXA) is the most reliable form of diagnosing osteoporosis and managing pharmacological treatment regimens. However, changes in BMD occur slowly (i.e., several months) and DXA does not reflect the metabolic rate of bone turnover. Alternatively, biochemical bone turnover markers (BTM) are metabolic indicators released into serum and/or urine, and their quantity reflects the metabolic activity of bone...
July 4, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28672432/pros-and-cons-while-looking-through-an-asian-window-on-the-rome-iv-criteria-for-irritable-bowel-syndrome-pros
#13
REVIEW
Uday C Ghoshal
A decade after Rome III, in 2016, Rome IV criteria were published. There are major differences between Rome IV and the earlier iteration, some of which are in line with Asian viewpoints. The clinical applicability of the Rome IV criteria of irritable bowel syndrome (IBS) in Asian perspective is reviewed here. Instead of considering functional gastrointestinal disorders (FGIDs) to be largely psychogenic, Rome IV suggested the importance of the gut over brain ("disorders of gut-brain interaction" not "brain-gut interaction")...
July 30, 2017: Journal of Neurogastroenterology and Motility
https://www.readbyqxmd.com/read/28671618/vascular-mechanobiology-towards-control-of-in-situ-regeneration
#14
REVIEW
Eline E van Haaften, Carlijn V C Bouten, Nicholas A Kurniawan
The paradigm of regenerative medicine has recently shifted from in vitro to in situ tissue engineering: implanting a cell-free, biodegradable, off-the-shelf available scaffold and inducing the development of functional tissue by utilizing the regenerative potential of the body itself. This approach offers a prospect of not only alleviating the clinical demand for autologous vessels but also circumventing the current challenges with synthetic grafts. In order to move towards a hypothesis-driven engineering approach, we review three crucial aspects that need to be taken into account when regenerating vessels: (1) the structure-function relation for attaining mechanical homeostasis of vascular tissues, (2) the environmental cues governing cell function, and (3) the available experimental platforms to test instructive scaffolds for in situ tissue engineering...
July 3, 2017: Cells
https://www.readbyqxmd.com/read/28652174/trigeminal-neuralgia-tn-a-descriptive-literature-analysis-on-the-diagnosis-and-management-modalities
#15
A Alshukry, F Salburgo, L Jaloux, J-P Lavieille, M Montava
OBJECTIVE: The primary objective of this review is to explore the different aspects of the diagnosis and management of Trigeminal neuralgia (TN). We look at the role of radiological imaging in the work-up of this condition, and based on the findings in the literature, we report data on the medical and surgical management of TN. MATERIALS AND METHODS: A literature review was conducted using PubMed and Cochrane search engines in order to explore the data available on the diagnosis and management of TN...
June 23, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28652063/comparator-choice-in-caries-prevention-and-management-trials
#16
Falk Schwendicke, Nicola Innes, Colin Levey, Thomas Lamont, Gerd Göstemeyer
Comparator choice has been found one major factor impacting on the overall evidence supporting clinical interventions. We performed social network analysis on trials on the prevention/management of caries/carious lesions, hypothesizing that certain comparators are proportionally over-investigated, and others under-investigated, and that comparisons within comparator classes are preferred over comparisons between classes. A systematic review of randomized controlled trials on the prevention/management of caries/existing carious lesions was carried out...
June 23, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28644991/glimpses-into-the-blind-spot-social-interaction-and-autism
#17
REVIEW
Kristen Bottema-Beutel
A primary feature of autism spectrum disorder (ASD) is marked difficulty in social interactions. Despite the centrality of social interaction differences to the clinical presentation of ASD, only a small portion of research in this field characterizes interaction in everyday social contexts. This theoretical paper reviews the growing corpus of interactional research on ASD, including discourse analysis (DA) and conversation analysis (CA) approaches. DA and CA are micro-analytic methods aimed at understanding the organizational structure of, and actions pursued within, social encounters...
June 16, 2017: Journal of Communication Disorders
https://www.readbyqxmd.com/read/28640544/interactions-of-neurons-with-physical-environments
#18
REVIEW
Michal Marcus, Koby Baranes, Matthew Park, Insung S Choi, Kyungtae Kang, Orit Shefi
Nerve growth strongly relies on multiple chemical and physical signals throughout development and regeneration. Currently, a cure for injured neuronal tissue is an unmet need. Recent advances in fabrication technologies and materials led to the development of synthetic interfaces for neurons. Such engineered platforms that come in 2D and 3D forms can mimic the native extracellular environment and create a deeper understanding of neuronal growth mechanisms, and ultimately advance the development of potential therapies for neuronal regeneration...
June 22, 2017: Advanced Healthcare Materials
https://www.readbyqxmd.com/read/28634897/the-effect-of-surgical-technique-and-spacer-texture-on-bone-regeneration-a-caprine-study-using-the-masquelet-technique
#19
Viviane Luangphakdy, G Elizabeth Pluhar, Nicolás S Piuzzi, Jean-Claude D'Alleyrand, Cathy S Carlson, Joan E Bechtold, Jonathan Forsberg, George F Muschler
BACKGROUND: The Masquelet-induced-membrane technique is a commonly used method for treating segmental bone defects. However, there are no established clinical standards for management of the induced membrane before grafting. QUESTIONS/PURPOSES: Two clinically based theories were tested in a chronic caprine tibial defect model: (1) a textured spacer that increases the induced-membrane surface area will increase bone regeneration; and (2) surgical scraping to remove a thin tissue layer of the inner induced-membrane surface will enhance bone formation...
June 20, 2017: Clinical Orthopaedics and related Research
https://www.readbyqxmd.com/read/28620300/novel-anti-fibrotic-therapies
#20
REVIEW
Benita L McVicker, Robert G Bennett
Fibrosis is a major player in cardiovascular disease, both as a contributor to the development of disease, as well as a post-injury response that drives progression. Despite the identification of many mechanisms responsible for cardiovascular fibrosis, to date no treatments have emerged that have effectively reduced the excess deposition of extracellular matrix associated with fibrotic conditions. Novel treatments have recently been identified that hold promise as potential therapeutic agents for cardiovascular diseases associated with fibrosis, as well as other fibrotic conditions...
2017: Frontiers in Pharmacology
keyword
keyword
109485
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"