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https://www.readbyqxmd.com/read/29690873/insecticide-treated-nets-mass-distribution-campaign-benefits-and-lessons-in-zambia
#1
REVIEW
Freddie Masaninga, Nawa Mukumbuta, Ketty Ndhlovu, Busiku Hamainza, Pauline Wamulume, Emmanuel Chanda, John Banda, Mercy Mwanza-Ingwe, John M Miller, Birkinesh Ameneshewa, Abraham Mnzava, Elizabeth Kawesha-Chizema
BACKGROUND: Zambia was an early adopter of insecticide-treated nets strategy in 2001, and policy for mass distribution with long-lasting insecticidal nets (LLINs) in 2005. Since then, the country has implemented mass distribution supplemented with routine delivery through antenatal care and under five clinics in health facilities. The national targets of universal (100%) coverage and 80% utilization of LLINs have not been attained. Free mass LLIN distribution campaign in Zambia offers important lessons to inform future campaigns in the African region...
April 24, 2018: Malaria Journal
https://www.readbyqxmd.com/read/29682251/implant-abutment-connections-on-single-crowns-a-systematic-review
#2
REVIEW
F M Ceruso, P Barnaba, S Mazzoleni, L Ottria, M Gargari, A Zuccon, G Bruno, A DI Fiore
Different implant-abutment connections have been developed in the effort of reducing mechanical and biological failure. The most frequent complications are screw loosening, abutment or implant fracture and marginal bone loss due to overload and bacterial micro-leakage. Ideal connection should work as a one-piece implant avoiding the formation of a micro-gap at the implant-abutment interface. Different in vitro and in vivo researches have been published to compare the implant-abutment connections actually available: external hexagon, internal hexagon and conical finding different amount of micro-gap, micro-leakage and marginal bone loss...
October 2017: Oral & Implantology
https://www.readbyqxmd.com/read/29675049/administration-of-intravenous-morphine-for-acute-pain-in-the-emergency-department-inflicts-an-economic-burden-in-europe
#3
Montserrat Casamayor, Karen DiDonato, Marc Hennebert, Luca Brazzi, Gregor Prosen
Background: Acute pain is among the leading causes of referral to the emergency department (ED) in industrialized countries. Its management mainly depends on intensity. Moderate-to-severe pain is treated with intravenous (IV) administered opioids, of which morphine is the most commonly used in the ED. We have estimated the burden of IV administration of morphine in the five key European countries (EU5) using a micro-costing approach. Scope: A structured literature review was conducted to identify clinical guidelines for acute pain management in EU5 and clinical studies conducted in the ED setting...
2018: Drugs in Context
https://www.readbyqxmd.com/read/29671050/-trabecular-micro-invasive-glaucoma-surgery-procedures-and-clinical-results
#4
REVIEW
A G M Jünemann, R Rejdak, B Hohberger
The management of glaucoma therapy to reduce intraocular pressure commonly consists of a gradual approach with local monotherapy, combined therapy, laser surgery and finally filtration surgery. The local side effects of glaucoma medications and the lack of adherence and persistence to the medical therapy as well as the complication profile of the established glaucoma surgical techniques justify the introduction of new surgical procedures. Micro-invasive glaucoma surgery (MIGS) is a promising new surgical approach...
April 18, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29664222/recent-developments-and-clinical-potential-on-decellularized-adipose-tissue
#5
REVIEW
Jia Dong, Mei Yu, Yan Zhang, Yin Yin, Weidong Tian
Natural and synthetic materials have been developed to provide a three-dimensional (3-D) scaffold that mimics the extracellular matrix properties for tissue regeneration and reconstruction. On account of the excellent biological and mechanical properties, diverse decellularized tissue materials have been developed as natural scaffolds. Among them, decellularized adipose tissue (DAT) has generated great interest in recent years due to the extensiveness of the source and the eximious potential to enhance the regeneration and repair of damaged tissues...
April 17, 2018: Journal of Biomedical Materials Research. Part A
https://www.readbyqxmd.com/read/29650198/analysis-on-the-implementation-of-a-health-improvement-project-garbage-clinical-insurance-in-indonesia-a-literature-review
#6
Efa Apriyanti
OBJECTIVE: Indonesia Medika has established "Garbage Clinical Insurance" (GCI), which enables the population below the poverty line (BPL) to obtain health insurance by donating their garbage to pay the premium. The objective of this paper was to critically examine the implementation of GCI in Indonesia by reviewing the background, effects, and sustainability of this program. METHOD: A literature search of studies related to GCI, other types of micro health insurance, and their applications in developing countries was conducted...
February 2018: Enfermería Clínica
https://www.readbyqxmd.com/read/29627916/necrotizing-fasciitis-case-series-and-review-of-the-literature-on-clinical-and-medico-legal-diagnostic-challenges
#7
Paolo Fais, Alessia Viero, Guido Viel, Renzo Giordano, Dario Raniero, Stefano Kusstatscher, Chiara Giraudo, Giovanni Cecchetto, Massimo Montisci
Necrotizing fasciitis (NF) is a life-threatening infection of soft tissues spreading along the fasciae to the surrounding musculature, subcutaneous fat and overlying skin areas that can rapidly lead to septic shock and death. Due to the pandemic increase of medical malpractice lawsuits, above all in Western countries, the forensic pathologist is frequently asked to investigate post-mortem cases of NF in order to determine the cause of death and to identify any related negligence and/or medical error. Herein, we review the medical literature dealing with cases of NF in a post-mortem setting, present a case series of seven NF fatalities and discuss the main ante-mortem and post-mortem diagnostic challenges of both clinical and forensic interests...
April 7, 2018: International Journal of Legal Medicine
https://www.readbyqxmd.com/read/29627819/elements-of-integrated-care-approaches-for-older-people-a-review-of-reviews
#8
Andrew M Briggs, Pim P Valentijn, Jotheeswaran A Thiyagarajan, Islene Araujo de Carvalho
OBJECTIVE: The World Health Organization (WHO) recently proposed an Integrated Care for Older People approach to guide health systems and services in better supporting functional ability of older people. A knowledge gap remains in the key elements of integrated care approaches used in health and social care delivery systems for older populations. The objective of this review was to identify and describe the key elements of integrated care models for elderly people reported in the literature...
April 7, 2018: BMJ Open
https://www.readbyqxmd.com/read/29624982/clinical-interventions-in-osteosarcopenic-obesity-nutrition-physical-and-psychological-activity
#9
Ana Isabel García-González, Zoraida Axtle-Serrano, Miriam López-Teros, Claudia Szlejf, Adrián Martínez-Ruiz, Oscar Rosas-Carrasco
Osteosarcopenic obesity (OSO) is a condition associated with adverse outcomes in older adults. Since it is a condition which includes three tissues (obesity, sarcopenia and osteopenia/osteoporosis), it requires simultaneous and multidisciplinary clinical interventions to revert it. Until this moment, there have been published review articles only focused on nutrition or physical activity. However, we believe that assembling the existing evidence on potential treatments (nutritional intervention with micro- and macronutrients), physical activity, farmacological treatment for osteopenia/osteoporosis, possible farmacological treatment for sarcopenia, and, finally, psychological interventions focused on the treatment of psychiatric comorbidities (such as anxiety or depression) will help healthcare providers to improve the body composition of older adults...
2018: Revista Médica del Instituto Mexicano del Seguro Social
https://www.readbyqxmd.com/read/29614790/microrna-regulation-of-telomerase-reverse-transcriptase-tert-micro-machines-pull-strings-of-papier-m%C3%A3-ch%C3%A3-puppets
#10
REVIEW
Ammad Ahmad Farooqi, Qaisar Mansoor, Nada Alaaeddine, Baojun Xu
Substantial fraction of high-quality information is continuously being added into the existing pool of knowledge related to the biology of telomeres. Based on the insights gleaned from decades of research, it is clear that chromosomal stability needs a highly controlled and dynamic balance of DNA gain and loss in each terminal tract of telomeric repeats. Telomeres are formed by tandem repeats of TTAGGG sequences, which are gradually lost with each round of division of the cells. Targeted inhibition of telomerase to effectively induce apoptosis in cancer cells has attracted tremendous attention and overwhelmingly increasingly list of telomerase inhibitors truthfully advocates pharmacological significance of telomerase...
April 1, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29596948/what-is-the-best-strategy-on-detection-of-cornea-neuropathy-in-people-with-diabetes-recent-advances-in-potential-measurements
#11
REVIEW
Ying Lv, Shaozhen Zhao
There are well-acknowledged clinical or pre-clinical measurements concerning diabetic peripheral neuropathy(DPN). The current gold standard for diagnosis of diabetic peripheral neuropathy is nerve conduction suitable for detecting large nerve fiber function[1] and intraepidermal nerve fiber density assessment for small fiber damage evaluation[2]. The lack of a sensitive, non-invasive, and repeatable endpoint to measure changes in small nerve fibers is a major factor holding back clinical trials for the treatment of diabetic peripheral neuropathy...
March 26, 2018: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/29578264/influence-of-different-implant-geometry-in-clinical-longevity-and-maintenance-of-marginal-bone-a-systematic-review
#12
REVIEW
Sabrina Telles Lovatto, Rafaela Bassani, Rafael Sarkis-Onofre, Mateus Bertolini Fernandes Dos Santos
PURPOSE: To assess, through a systematic review, the influence of different implant geometries on clinical longevity and maintenance of marginal bone tissue. METHODS: An electronic search was conducted in MEDLINE, Scopus, and Web of Science databases, limited to studies written in English from 1996 to 2017 using specific search strategies. Only randomized controlled trials (RCTs) that compared dental implants and their geometries were included. Two reviewers independently selected studies, extracted data, and assessed the risk of bias of included studies...
March 26, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
https://www.readbyqxmd.com/read/29569086/pediatric-cerebellar-pilocytic-astrocytoma-presenting-with-spontaneous-intratumoral-hemorrhage
#13
REVIEW
Carmine Antonio Donofrio, Filippo Gagliardi, Marcella Callea, Camillo Ferrari da Passano, Maria Rosa Terreni, Andrea Cavalli, Alfio Spina, Stefania Acerno, Michele Bailo, Samer K Elbabaa, Pietro Mortini
Pilocytic astrocytomas (PAs) are benign glial tumors and one of the most common childhood posterior fossa tumors. Spontaneous intratumoral hemorrhage in PAs occurs occasionally, in about 8-20% of cases. Cerebellar hemorrhages in pediatric population are rare and mainly due to head injuries, rupture of vascular malformations, infections, or hematological diseases. We have investigated the still controversial and unclear pathophysiology underlying intratumoral hemorrhage in PAs. Bleeding in low-grade tumors might be related to structural abnormalities and specific angio-architecture of tumor vessels, such as degenerative mural hyalinization, "glomeruloid" endothelial proliferation, presence of encased micro-aneurysms, and glioma-induced neoangiogenesis...
March 22, 2018: Neurosurgical Review
https://www.readbyqxmd.com/read/29566947/intraoperative-sentinel-lymph-node-evaluation-optimizing-surgical-pathology-practices-in-an-era-of-changing-clinical-management
#14
Margaret L Compton, Raeshell S Sweeting, Emily S Reisenbichler
Axillary lymph node status is an independent prognostic indicator in breast cancer. Intraoperative identification of metastatic carcinoma in sentinel lymph nodes may allow for concurrent axillary lymph node dissection at the time of primary tumor excision. A retrospective review of patients undergoing primary breast cancer excision with sentinel lymph node sampling was performed. Sensitivity and specificity of imprint cytology (touch prep) with and without the incorporation of gross evaluation was determined using permanent section results as the gold standard...
April 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29565935/cost-implications-of-avoidable-rapid-response-call-activations-in-older-patients
#15
Ashwin Subramaniam, Cameron Green, Mohammad Omair, Lionel Soh, Aun Chian Yeoh, Ravindranath Tiruvoipati
BACKGROUND: Rapid response calls (RRCs) are designed to appropriately manage clinical deterioration. However, not all RRCs are appropriate due to medical futility or the patient's wishes. Incidence and costs associated with avoidable-RRC (ARRC) remain underexplored. AIMS: The aim of this study was to describe the incidence and costs of ARRC activations in older patients. METHODS: We retrospectively reviewed RRCs in patients aged ≥80 years over six months...
March 23, 2018: New Zealand Medical Journal
https://www.readbyqxmd.com/read/29564196/selection-of-tubular-and-endoscopic-transforaminal-disc-procedures-based-on-disc-size-location-and-characteristics
#16
REVIEW
Ovidiu Palea, Michelle Granville, Robert E Jacobson
The clinical effectiveness of percutaneous and transforaminal endoscopic discectomy procedures has been evaluated by the system used or compared to open laminectomy or micro-discectomy but are not evaluated based on the location and characteristics of the abnormal disc. This review proposes that outcomes are primarily related to disc size, biomechanics, location, and associated segmental fibrotic and bone changes as well as the surgeon's skill in using various systems rather than the specific system used...
January 20, 2018: Curēus
https://www.readbyqxmd.com/read/29559838/decellularized-hydrogels-in-bone-tissue-engineering-a-topical-review
#17
REVIEW
Andrea Pacifici, Luigi Laino, Marco Gargari, Federico Guzzo, Andrea Velandia Luz, Antonella Polimeni, Luciano Pacifici
Nowadays, autograft and allograft techniques represent the main solution to improve bone repair. Unfortunately, autograft technique is expensive, invasive and subject to infections and hematoma, frequently affecting both donor sites and surgical sites. A recent advance in tissue engineering is the fabrication of cell-laden hydrogels with custom-made geometry, depending on the clinical case. The use of ECM (Extra-Cellular Matrix)-derived Hydrogels from bone tissue is the new opportunity to obtain good results in bone regeneration...
2018: International Journal of Medical Sciences
https://www.readbyqxmd.com/read/29526176/-the-initial-experience-of-video-assisted-thoracic-surgery-segmentectomy-for-early-stage-lung-cancer
#18
Shaohua Ma, Tiansheng Yan, Keyi Wang, Jingdi Wang, Jintao Song, Tong Wang, Wei He, Jie Bai, Liang Jin, Hailong Liang
BACKGROUND: Segmentectomy can retains more healthy lung tissue than lobectomy, but it remains controversial in oncology for early stage lung cancer. The aim of this study is to discuss the problems of video-assisted thoracic surgery (VATS) segmentectomy in early stage lung cancer, by analyzing the clinical and pathological data of 35 cases and reviewing the literature. METHODS: There were 35 patients who received segmentectomy by complete video-assisted thoracic surgery, from May 2013 to July 2017, in single operation group in the Third Hospital of Peking University...
February 20, 2018: Zhongguo Fei Ai za Zhi, Chinese Journal of Lung Cancer
https://www.readbyqxmd.com/read/29525090/advancing-the-frontiers-of-silk-fibroin-protein-based-materials-for-futuristic-electronics-and-clinical-wound-healing-invited-review
#19
REVIEW
Leng-Duei Koh, Jingjie Yeo, Yeong Yuh Lee, Qunya Ong, Mingyong Han, Benjamin C-K Tee
The present review will introduce the basic concepts of silk-based electronics/optoelectronics including the latest technological advances on the use of silk fibroin in combination with other functional components, with an emphasis on improving the performance of next-generation silk-based materials. It also highlights the patterning of silk fibroin to produce micro/nano-scale features, as well as the functionalization of silk fibroin to impart antimicrobial (i.e. antibacterial) properties. Silk-based bioelectronics have great potential for advanced or futuristic bio-applications including e-skins, e-bandages, biosensors, wearable displays, implantable devices, artificial muscles, etc...
May 1, 2018: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/29521220/kidney-on-a-chip-a-new-technology-for-predicting-drug-efficacy-interactions-and-drug-induced-nephrotoxicity
#20
Jeonghwan Lee, Sejoong Kim
The kidneys play a pivotal role in most drug-removal processes and are important when evaluating drug safety. Kidney dysfunction resulting from various drugs is an important issue in clinical practice and during the drug development process. Traditional in vivo animal experiments are limited with respect to evaluating drug efficacy and nephrotoxicity due to discrepancies in drug pharmacokinetics and pharmacodynamics between humans and animals, and static cell culture experiments cannot fully reflect the actual microphysiological environment in humans...
March 8, 2018: Current Drug Metabolism
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