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nausea and vomitting in palliative care

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https://www.readbyqxmd.com/read/28821989/prevalence-of-hyponatremia-in-inpatients-with-incurable-and-life-limiting-diseases-and-its-association-with-physical-symptoms-a-retrospective-descriptive-study
#1
Kerstin Kremeike, Ricarda M L Wetter, Volker Burst, Raymond Voltz, Kathrin Kuhr, Steffen T Simon
PURPOSE: Hyponatremia is a common electrolyte abnormality seen in hospitalized patients. It may cause a variety of symptoms and is associated with longer hospitalizations and higher mortality. However, to date, only little is known about the extent of hyponatremia in patients with incurable diseases and whether it is associated with physical symptoms in this patient group. This study aims to describe the prevalence of hyponatremia, associated symptoms, and symptom intensity in inpatients with hyponatremia receiving specialist palliative care (SPC)...
August 18, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28807703/is-early-palliative-care-feasible-in-patients-with-multiple-myeloma
#2
Josep Porta-Sales, Maria Guerrero-Torrelles, Deborah Moreno-Alonso, Josep Sarra-Escarre, Victòria Clapés-Puig, Jordi Trelis-Navarro, Anna Sureda-Balarí, Alberto Fernández De Sevilla-Ribosa
CONTEXT: Evidence for the benefits of early palliative care (EPC) in patients with solid tumors is strong, but EPC has received scant attention in hematological malignancies. OBJECTIVE: To assess the benefits of outpatient-based EPC for symptom control in patients with multiple myeloma. METHODS: Retrospective study of patients attending the Multiple Myeloma Palliative Care Clinic (MM-PAL) at our hospital in the year 2013 (February 1 - December 31)...
August 11, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/28772094/pharmacovigilance-in-hospice-palliative-care-net-effect-of-haloperidol-for-nausea-or-vomiting
#3
Madeline Digges, Akram Hussein, Andrew Wilcock, Gregory B Crawford, Jason W Boland, Meera R Agar, Aynharan Sinnarajah, David C Currow, Miriam J Johnson
BACKGROUND: Haloperidol is widely prescribed as an antiemetic in patients receiving palliative care, but there is limited evidence to support and refine its use. OBJECTIVE: To explore the immediate and short-term net clinical effects of haloperidol when treating nausea and/or vomiting in palliative care patients. DESIGN: A prospective, multicenter, consecutive case series. SETTING/SUBJECTS: Twenty-two sites, five countries: consultative, ambulatory, and inpatient services...
August 3, 2017: Journal of Palliative Medicine
https://www.readbyqxmd.com/read/28695173/identification-of-symptom-clusters-in-cancer-patients-at-palliative-care-clinic
#4
Gülçin Şenel Özalp, Neşe Uysal, Gonca Oğuz, Nesteren Koçak, Şerife Karaca, Nihan Kadıoğulları
OBJECTIVE: Cancer patients often experience a large number of symptoms together. The aim of this study is to determine the symptom clusters in cancer patients at palliative care clinic. METHODS: Hundred and seventy consecutive patients were enrolled in the study. Memorial Symptom Assessment Scale was used for symptom assessment of the patients. RESULTS: The most experienced symptoms by the patients during the past week before hospitalization in palliative care clinic were lack of energy (95...
July 2017: Asia-Pacific Journal of Oncology Nursing
https://www.readbyqxmd.com/read/28671265/corticosteroids-for-adult-patients-with-advanced-cancer-who-have-nausea-and-vomiting-not-related-to-chemotherapy-radiotherapy-or-surgery
#5
REVIEW
Petra Vayne-Bossert, Alison Haywood, Phillip Good, Sohil Khan, Kirsty Rickett, Janet R Hardy
BACKGROUND: Nausea is a common symptom in advanced cancer, with a prevalence of up to 70%. While nausea and vomiting can be related to cancer treatments, such as chemotherapy, radiotherapy, or surgery, a significant number of people with advanced cancer also suffer from nausea unrelated to such therapies. Nausea and vomiting may also cause psychological distress, and have a negative impact on the quality of life of cancer patients; similarly to pain, nausea is often under-treated. The exact mechanism of action of corticosteroids on nausea is unclear, however, they are used to manage a number of cancer-specific complications, including spinal cord compression, raised intracranial pressure, and lymphangitis carcinomatosis...
July 3, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28651827/effects-of-nutrition-and-physical-exercise-intervention-in-palliative-cancer-patients-a-randomized-controlled-trial
#6
Alexandra Uster, Maya Ruehlin, Stefanie Mey, David Gisi, Ruud Knols, Reinhard Imoberdorf, Miklos Pless, Peter E Ballmer
BACKGROUND & AIMS: Cancer cachexia is multifactorial and should be targeted using a multimodal form of intervention. The purpose of the present trial was to test the effects of a combined nutrition and physical exercise program on cancer patients with metastatic or locally advanced tumors of the gastrointestinal and lung tracts. METHODS: Patients were randomized into two groups: One group received a minimum of three standardized individual nutritional counselling sessions and participated in a 60-min exercise program twice a week...
June 8, 2017: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28646590/randomized-controlled-double-blind-trial-comparing-haloperidol-combined-with-conventional-therapy-to-conventional-therapy-alone-in-patients-with-symptomatic-gastroparesis
#7
Carlos J Roldan, Kimberly A Chambers, Linda Paniagua, Sonali Patel, Marylou Cardenas-Turanzas, Yashwant Chathampally
OBJECTIVE: Gastroparesis is a debilitating condition that causes nausea, vomiting, and abdominal pain. Management includes analgesics and antiemetics, but symptoms are often refractory. Haloperidol has been utilized in the palliative care setting for similar symptoms. The study objective was to determine whether haloperidol as an adjunct to conventional therapy would improve symptoms in gastroparesis patients presenting to the emergency department (ED). STUDY DESIGN AND METHODS: This was a randomized, double-blind, placebo-controlled trial of adult ED patients with acute exacerbation of previously diagnosed gastroparesis...
June 24, 2017: Academic Emergency Medicine: Official Journal of the Society for Academic Emergency Medicine
https://www.readbyqxmd.com/read/28494643/randomised-clinical-trial-of-early-specialist-palliative-care-plus-standard-care-versus-standard-care-alone-in-patients-with-advanced-cancer-the-danish-palliative-care-trial
#8
Mogens Groenvold, Morten Aagaard Petersen, Anette Damkier, Mette Asbjoern Neergaard, Jan Bjoern Nielsen, Lise Pedersen, Per Sjøgren, Annette Sand Strömgren, Tove Bahn Vejlgaard, Christian Gluud, Jane Lindschou, Peter Fayers, Irene J Higginson, Anna Thit Johnsen
BACKGROUND: Beneficial effects of early palliative care have been found in advanced cancer, but the evidence is not unequivocal. AIM: To investigate the effect of early specialist palliative care among advanced cancer patients identified in oncology departments. SETTING/PARTICIPANTS: The Danish Palliative Care Trial (DanPaCT) (ClinicalTrials.gov NCT01348048) is a multicentre randomised clinical trial comparing early referral to a specialist palliative care team plus standard care versus standard care alone...
May 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28427740/a-study-of-the-incidence-and-management-of-admissions-for-cancer-related-symptoms-in-a-district-general-hospital-the-potential-role-of-an-acute-oncology-service
#9
C M Bruce, J Smith, A Price
AIMS: The non-specialist management of cancer patients is becoming increasingly complex. Acute oncology services (AOS), aiming to provide rapid access to specialist advice, have been shown to improve patient experience and reduce length of inpatient stay. The present study aimed to inform service provision in a district general hospital (DGH) by investigating cancer patients, not on active anti-cancer treatment, where the disease itself precipitated admission. This is a vulnerable group who are potentially disenfranchised of focused oncological input due to having less robust care pathways established to date...
April 17, 2017: Clinical Oncology: a Journal of the Royal College of Radiologists
https://www.readbyqxmd.com/read/28222994/palliative-care-and-palliative-radiation-therapy-education-in-radiation-oncology-a-survey-of-us-radiation-oncology-program-directors
#10
Randy L Wei, Lauren E Colbert, Joshua Jones, Margarita Racsa, Gabrielle Kane, Steve Lutz, Neha Vapiwala, Kavita V Dharmarajan
PURPOSE: The purpose of this study was to assess the state of palliative and supportive care (PSC) and palliative radiation therapy (RT) educational curricula in radiation oncology residency programs in the United States. METHODS AND MATERIALS: We surveyed 87 program directors of radiation oncology residency programs in the United States between September 2015 and November 2015. An electronic survey on PSC and palliative RT education during residency was sent to all program directors...
December 1, 2016: Practical Radiation Oncology
https://www.readbyqxmd.com/read/28156509/palliative-care-and-palliative-radiotherapy-education-in-radiation-oncology-a-survey-of-us-radiation-oncology-program-directors
#11
Lauren Colbert, Joshua Adam Jones, Gabrielle Kane, Margarita Racsa-Alamgir, Neha Vapiwala, Kavita Vyas Dharmarajan
178 Background: To assess the state of palliative care education curricula in radiation oncology residency programs in the United States. METHODS: We surveyed 90 program directors of radiation oncology residency programs in the United States from September 2015 to November 2015. An electronic survey on palliative care education during residency was sent to all program directors. The survey consisted of questions on perceived relevance of palliative care in radiation oncology residency, formal didactics on domains of palliative care, effective teaching formats for palliative care education, and perceived barriers for integrating palliative care into the residency curriculum...
October 9, 2016: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/27822976/danish-general-practitioners-self-reported-competences-in-end-of-life-care
#12
Anna Winthereik, Mette Neergaard, Peter Vedsted, Anders Jensen
OBJECTIVE: General practitioners (GPs) are pivotal in end-of-life (EOL) care. This study aimed to assess GP-reported provision of EOL care and to assess associations with GP characteristics. DESIGN: Population-based questionnaire study. SETTING: Central Denmark Region with approximately 1.3 million inhabitants. SUBJECTS: All 843 active GPs in the Central Denmark Region were sent a questionnaire by mail. MAIN OUTCOME MEASURES: Responses to 18 items concerning four aspects: provision of EOL care to patients with different diagnosis, confidence with being a key worker, organisation of EOL care and EOL skills (medical and psychosocial)...
December 2016: Scandinavian Journal of Primary Health Care
https://www.readbyqxmd.com/read/27624994/symptom-clusters-and-survival-in-portuguese-patients-with-advanced-cancer
#13
Pedro C Barata, Alice Cardoso, Maria P Custodio, Marta Alves, Ana L Papoila, Barbosa António, Peter G Lawlor
This study aimed to identify clusters of symptoms, to determine the patient characteristics associated with identified, and determine their strength of association with survival in patients with advanced cancer (ACPs). Consecutively eligible ACPs not receiving cancer-specific treatment, and referred to a Tertiary Palliative Care Clinic, were enrolled in a prospective cohort study. At first consultation, patients rated 9 symptoms through the Edmonton Symptom Assessment System (0-10 scale) and 10 others using a Likert scale (1-5)...
September 13, 2016: Cancer Medicine
https://www.readbyqxmd.com/read/27559253/integration-of-early-specialist-palliative-care-in-cancer-care-survey-of-oncologists-oncology-nurses-and-patients
#14
Naveen Salins, Lipika Patra, M R Usha Rani, S O Lohitashva, Raghavendra Rao, Raghavendra Ramanjulu, Nandini Vallath
INTRODUCTION: Palliative care is usually delivered late in the course of illness trajectory. This precludes patients on active disease modifying treatment from receiving the benefit of palliative care intervention. A survey was conducted to know the opinion of oncologists, oncology nurses, and patients about the role of early specialist palliative care in cancer. METHODS: A nonrandomized descriptive cross-sectional study was conducted at a tertiary cancer care center in India...
July 2016: Indian Journal of Palliative Care
https://www.readbyqxmd.com/read/27531376/defining-high-quality-palliative-care-in-oncology-practice-an-american-society-of-clinical-oncology-american-academy-of-hospice-and-palliative-medicine-guidance-statement
#15
Kathleen E Bickel, Kristen McNiff, Mary K Buss, Arif Kamal, Dale Lupu, Amy P Abernethy, Michael S Broder, Charles L Shapiro, Anupama Kurup Acheson, Jennifer Malin, Tracey Evans, Monika K Krzyzanowska
PURPOSE: Integrated into routine oncology care, palliative care can improve symptom burden, quality of life, and patient and caregiver satisfaction. However, not all oncology practices have access to specialist palliative medicine. This project endeavored to define what constitutes high-quality primary palliative care as delivered by medical oncology practices. METHODS: An expert steering committee outlined 966 palliative care service items, in nine domains, each describing a candidate element of primary palliative care delivery for patients with advanced cancer or high symptom burden...
September 2016: Journal of Oncology Practice
https://www.readbyqxmd.com/read/27511479/initial-experience-with-delivery-of-palliative-care-toterminal-cancer-patients
#16
Mustafa Süren, İsmail Okan, Ziya Kaya, Serkan Karaman, Semih Arici, Mevlüt Çömlekçi, Murat Ayan, Mehmet Esen, Serkan Doğru, Aynur Şahin, Tuğba Karaman
BACKGROUND/AIM: We investigated the symptoms and needs of terminal cancer patients in a region where formal palliative care is limited. Here we present the demographic features and symptoms of end-stage cancer patients living in a city in northern Turkey. MATERIALS AND METHODS: The study was conducted at Gaziosmanpaşa University (Tokat, Turkey), in 2011 and 2012. End-stage cancer patients admitted or referred by various departments to our outpatient pain unit were included...
February 17, 2014: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27490069/care-of-patients-at-the-end-of-life-management-of-nonpain-symptoms
#17
Florence T Baralatei, Richard J Ackermann
Management of nonpain symptoms can improve quality of life for patients at the end of life and their family members. Constipation is the most common nonpain symptom. It can be related to opioid therapy and/or medical conditions. After abdominal examination to detect masses or evidence of bowel obstruction and rectal examination to exclude fecal impaction, constipation should be managed with a stimulant laxative (eg, senna) or an osmotic laxative (eg, sorbitol). Dyspnea also is common, and often improves with use of a fan to blow air into the face, as well with breathing and relaxation exercises...
August 2016: FP Essentials
https://www.readbyqxmd.com/read/27068607/reliability-and-validity-of-the-turkish-version-of-the-eortc-qlq-c15-pal-for-patients-with-advanced-cancer
#18
Hanife Ozcelik, Yasemin Guzel, Esra Sonmez, Fatma Aksoy, Ruchan Uslu
OBJECTIVE: Assessing quality of life, which is the main focus of palliative care, is highly important. The number of available, specific, simple, and valid assessment instruments for patients with advanced cancer in Turkey is limited. The aim of our study was to perform a psychometric evaluation of the Turkish version of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 15-PAL (EORTC QLQ-C15-PAL). METHOD: The study was conducted in İzmir with patients who had received treatment in the palliative care unit of a university hospital between November of 2011 and December of 2013...
December 2016: Palliative & Supportive Care
https://www.readbyqxmd.com/read/27030166/opioids-for-the-palliation-of-refractory-breathlessness-in-adults-with-advanced-disease-and-terminal-illness
#19
REVIEW
Hayley Barnes, Julie McDonald, Natasha Smallwood, Renée Manser
BACKGROUND: Breathlessness is a common and disabling symptom which affects many people with advanced cardiorespiratory disease and cancer. The most effective treatments are aimed at treating the underlying disease. However, this may not always be possible, and symptomatic treatment is often required in addition to maximal disease-directed therapy. Opioids are increasingly being used to treat breathlessness, although their mechanism of action is still not completely known. A few good sized, high quality trials have been conducted in this area...
March 31, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27028050/cancer-and-chemotherapy-induced-nausea-and-vomiting-a-focus-on-olanzapine
#20
Snezana M Bosnjak, Jelena Dimitrijevic, Fedja Djordjevic
PURPOSE OF THE REVIEW: The purpose of review is to critically present the evidence supporting the use of olanzapine, an atypical antipsychotic, as an antiemetic for cancer and chemotherapy-induced nausea and vomiting (CINV). RECENT FINDINGS: Two phase III clinical studies demonstrated superior efficacy of olanzapine in comparison with the neurokinin-1 receptor antagonists (NK1RA) for substance P (aprepitant, fosaprepitant) in the prevention of nausea after highly emetogenic chemotherapy...
June 2016: Current Opinion in Supportive and Palliative Care
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