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https://www.readbyqxmd.com/read/30235763/oral-health-status-of-adult-heart-transplant-recipients-in-china-a-cross-sectional-study
#1
Ying Cao, Xi Chen, Yixin Jia, Yalin Lv, Zheng Sun
Limited information on the oral health status of adult heart transplant recipients (HTRs) is known, and no available data exist in China. A prerequisite dental evaluation is usually recommended for patients' postorgan transplantation because lifelong immunosuppression may predispose them to infection spread.The aim of this study was to investigate the oral health status of Chinese adult HTRs and determine the association between oral health status and history of heart transplantation (HT).We carried out a cross-sectional study to collect clinical, demographic, socioeconomic, and behavioral data from 81 adult patients who received heart transplantation during 2014 to 2015 in China...
September 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/30235123/automated-quantification-of-bileaflet-mechanical-heart-valve-leaflet-angles-in-ct-images
#2
Ioannis Androulakis, Marguerite E Faure, Ricardo J P Budde, Theo van Walsum
Cardiac computed tomography (CT) is a valuable tool for functional mechanical heart valve (MHV) assessment. An important aspect of bileaflet MHV assessment is evaluation and measurement of leaflet opening and closing angles. Performed manually however, it is a laborious and time consuming task. In this paper, we propose an automated approach for bileaflet MHV leaflet angle computation. This method consists of four steps. After a one click selection of the MHV region on an axial image, an automatic MHV extraction using thresholding and connected component analysis based on voxel intensities is performed...
September 19, 2018: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/30234742/external-validation-of-the-quick-pediatric-logistic-organ-dysfunction-2-score-using-a-large-north-american-cohort-of-critically-ill-children-with-suspected-infection
#3
Matthias Görges, Cheryl Peters, Srinivas Murthy, Shanshan Pi, Niranjan Kissoon
OBJECTIVES: A quick Pediatric Logistic Organ Dysfunction 2 score on day 1, consisting of tachycardia, hypotension, and altered mentation, was shown to predict mortality with an area under the receiver operating characteristic curve of 82% (95% CI, 76-87%) in children admitted to a PICU with suspected infection. We performed an external validation of the quick Pediatric Logistic Organ Dysfunction 2, including its performance in predicting mortality in specific age groups. DESIGN: Analysis of retrospective data obtained from the Virtual Pediatric Systems PICU registry...
September 18, 2018: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/30233869/risk-factor-analysis-and-management-strategies-of-operating-room-related-infections-after-coronary-artery-bypass-grafting
#4
Lifen Pan, Shufang Tan, Linlan Cao, Xiaoling Feng
Background: To investigate and analyze the risk factors of operating room-related infections after coronary artery bypass grafting (CABG), to propose corresponding infection control management strategies, and to verify and evaluate the effectiveness of the strategy implementation. Methods: Patients with coronary heart disease who underwent CABG in a hospital from January 2015 to December 2016 were selected for inclusion in this study. The following patient variables were documented: demographics, history of underlying diseases (hypertension and diabetes), preoperative American Society of Anesthesiologists (ASA) score, skin preparation method, perioperative use of antibiotics, operation duration, intraoperative hypothermia, intraoperative blood loss, intraoperative blood transfusion, presence of visitors in the operating room, consecutive use of the same operating room, qualification of the surgeon, and surgical site infection...
August 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/30233479/hypertension-and-high-blood-pressure-are-associated-with-dementia-among-chinese-dwelling-elderly-the-shanghai-aging-study
#5
Xiaoniu Liang, Ying Shan, Ding Ding, Qianhua Zhao, Qihao Guo, Li Zheng, Wei Deng, Jianfeng Luo, Lap A Tse, Zhen Hong
Background: To explore the association between blood pressure and cognition in older participants in the Shanghai Aging Study. Methods: Data were drawn from 3,327 participants at the baseline of Shanghai Aging Study. History of hypertension was inquired and confirmed from participants' medical records. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured by research nurses in the early morning. Participants were diagnosed with "cognitive normal," "mild cognitive impairment (MCI)," or "dementia" by neurologists using DSM-IV and Petersen criteria...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/30232593/psychosocial-functioning-of-parents-of-children-with-heart-disease-describing-the-landscape
#6
Jo Wray, Amy Cassedy, Michelle M Ernst, Rodney C Franklin, Katherine Brown, Bradley S Marino
The aim was to describe the psychological functioning of parents of school-age children with heart disease (HD) in a large-scale, transnational evaluation of parent dyads across the spectrum of cardiac diagnoses and a range of psychosocial domains. Parents of children with HD attending routine out-patient cardiology follow-up visits completed questionnaires assessing their mental health, coping, and family functioning. Parents (1197 mothers and 1053 fathers) of 1214 children (mean age: 12.6 years; S.D. 3.0 years; median time since last surgery: 8...
September 19, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/30230963/body-temperature-heart-rate-and-short-term-outcome-of-cooled-infants
#7
Kennosuke Tsuda, Sachiko Iwata, Takeo Mukai, Jun Shibasaki, Akihito Takeuchi, Tomoaki Ioroi, Hiroyuki Sano, Nanae Yutaka, Akihito Takahashi, Toshiki Takenouchi, Satoshi Osaga, Takuya Tokuhisa, Sachio Takashima, Hisanori Sobajima, Masanori Tamura, Shigeharu Hosono, Makoto Nabetani, Osuke Iwata
Therapeutic hypothermia following neonatal encephalopathy is neuroprotective. However, approximately one in two cooled infants still die or develop permanent neurological impairments. Further understanding of variables associated with the effectiveness of cooling is important to improve the therapeutic regimen. To identify clinical factors associated with short-term outcomes of cooled infants, clinical data of 509 cooled infants registered to the Baby Cooling Registry of Japan between 2012 and 2014 were evaluated...
September 19, 2018: Therapeutic Hypothermia and Temperature Management
https://www.readbyqxmd.com/read/30228018/subclinical-atherosclerosis-in-patients-with-cyanotic-congenital-heart-disease
#8
Julie Bjerre Tarp, Mathias Holm Sørgaard, Christina Christoffersen, Annette Schophuus Jensen, Henrik Sillesen, David Celermajer, Peter Eriksson, Mette-Elise Estensen, Edit Nagy, Niels-Henrik Holstein-Rathlou, Thomas Engstrøm, Lars Søndergaard
INTRODUCTION: Survival in patients with cyanotic congenital heart disease (CCHD) has improved dramatically. The result is an ageing population with risk of acquired heart disease. Previous small uncontrolled studies suggested that these patients are protected against the development of atherosclerosis. To test this hypothesis, we sought to determine the prevalence of subclinical atherosclerosis in a larger population of patients with CCHD. METHOD: We compared the prevalence of subclinical atherosclerosis in adult CCHD patients from Denmark, Sweden, Norway and Australia, with that in age-, sex-, smoking status-, and body mass index matched controls...
September 3, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/30227980/original-research-aerosolized-lidocaine-effective-for-safer-arousal-after-suspension-laryngoscopy
#9
Ceki Paltura, Ahmet Güvenç, Ömer Necati Develioğlu, Kürşat Yelken, Mehmet Külekçi
AIM: To examine the systemic and local effects of the lidocaine on the larynx and trachea which is applied after the end of the surgery and through various application methods. STUDY DESIGN: Randomized controlled prospective study. METHOD: The study is composed of patients who underwent suspension laryngoscopy (SL) for benign laryngeal diseases (cysts, polyp, granuloma, etc) and American Society of Anesthesiologists (ASA) I, between January 2017 and January 2018...
September 15, 2018: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/30227964/embolic-and-other-adverse-outcomes-in-symptomatic-versus-asymptomatic-patients-with-atrial-fibrillation-from-the-orbit-af-registry
#10
Munveer Thind, DaJuanicia N Holmes, Marwan Badri, Karen S Pieper, Amitoj Singh, Rosalia G Blanco, Benjamin Steinberg, Gregg C Fonarow, Bernard J Gersh, Kenneth W Mahaffey, Eric D Peterson, James A Reiffel, Jonathan P Piccini, Peter R Kowey
Asymptomatic atrial fibrillation (AF) is being increasingly diagnosed via implantable devices, screening, and inpatient telemetry. Management of asymptomatic AF is controversial, in part, because the associated risks have not been well described. We examined the incidence of major adverse outcomes in patients with asymptomatic versus symptomatic AF using Outcomes Registry for Better Informed Treatment of Atrial, a nationwide US registry of AF patients. We compared stroke and/or non-central nervous system (CNS) embolism, major adverse cardiovascular and neurologic events, bleeding, and death in 9,319 asymptomatic (defined by European Heart Rhythm Association score = 1 or "no symptoms") versus symptomatic patients...
August 20, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30227961/comparison-of-early-and-long-term-outcomes-after-transcatheter-aortic-valve-implantation-in-patients-with-new-york-heart-association-functional-class-iv-to-those-in-class-iii-and-less
#11
Marianna Adamo, Claudia Fiorina, Anna Sonia Petronio, Cristina Giannini, Corrado Tamburino, Marco Barbanti, Francesco Bedogni, Luca Testa, Antonio Colombo, Azeem Latib, Giuseppe Bruschi, Bernhard Reimers, Arnaldo Poli, Marco Stefano Nazzaro, Salvatore Curello, Federica Ettori
Our aim was to investigate the impact of a baseline New York Heart Association (NYHA) class IV on clinical outcomes of a large real-world population who underwent transcatheter aortic valve implantation (TAVI). The primary end points were all-cause mortality, cardiovascular mortality, and re-hospitalization, evaluated at the longest available follow-up and by means of a 3-month landmark analysis. The secondary end points were: change in NYHA class, left ventricular ejection fraction, pulmonary pressure and mitral regurgitation...
August 21, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/30227349/sudomotor-dysfunction-is-frequent-and-correlates-with-disability-in-friedreich-ataxia
#12
Karen A G Takazaki, Thiago Junqueira R Rezende, Alberto R M Martinez, Carelis Gonzalez-Salazar, Anamarli Nucci, Iscia Lopes-Cendes, Marcondes C França
OBJECTIVES: To evaluate autonomic symptoms and function in Friedreich's Ataxia (FRDA). METHODS: Twenty-eight FRDA patients and 24 controls underwent clinical/electrophysiological testing. We employed the Friedreich's Ataxia Rating Scale (FARS) and the Scales for Outcomes in Parkinson's Disease: Autonomic Questionnaire-SCOPA-AUT to estimate the intensity of ataxia and autonomic complaints, respectively. Cardiovagal tests and the quantitative sudomotor axonal reflex, Q-SART, were then assessed in both groups...
August 31, 2018: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/30227128/development-of-a-congenital-heart-surgery-composite-quality-metric-part-2-analytic-methods
#13
Sean M O'Brien, Jeffrey P Jacobs, David M Shahian, Marshall L Jacobs, J William Gaynor, Jennifer C Romano, Michael G Gaies, Kevin D Hill, John E Mayer, Sara K Pasquali
BACKGROUND: We describe the statistical methods and results related to development of the first congenital heart surgery composite quality measure. METHODS: The composite measure was developed using the Society of Thoracic Surgeons (STS) Congenital Heart Surgery Database (2012-2015), Bayesian hierarchical modeling, and the current STS risk model for case-mix adjustment. It is comprised of a mortality domain (operative mortality), and morbidity domain [major complications, and post-operative length of stay (LOS)]...
September 15, 2018: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/30226082/superior-performance-in-prone-in-infants-with-congenital-heart-disease-predicts-an-earlier-onset-of-walking
#14
Lynn Dagenais, Manuela Materassi, Beatrice Desnous, Marie-Claude Vinay, Amélie Doussau, Pascale Sabeh, Joelle Prud'homme, Karine Gagnon BSc, Marien Lenoir, Marc-Antoine Charron, Anne Monique Nuyt, Nancy Poirier, Laurence Beaulieu-Genest, Lionel Carmant, Ala Birca
Infants with congenital heart disease are at risk of impaired neurodevelopment, which frequently manifests as motor delay during their first years of life. This delay is multifactorial in origin and environmental factors, such as a limited experience in prone, may play a role. In this study, we evaluated the motor development of a prospective cohort of 71 infants (37 males) with congenital heart disease at 4 months of age using the Alberta Infant Motor Scales (AIMS). We used regression analyses to determine whether the 4-month AIMS scores predict the ability to walk by 18 months...
September 18, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/30225923/development-of-simulation-combining-a-physical-heart-model-and-three-dimensional-system-for-electrophysiology-training
#15
Luca Rossi, Diego Penela, Lorenzo Doni, Raffaella Marazzi, Velia Napoli, Leonardo Napoli, Manola Vilotta, Giovanni Quinto Villani, Roberto De Ponti
BACKGROUND: A new three-dimensional heart anatomical simulator (3D HAS) has been created combining a physical heart model with an electroanatomic mapping (EAM) system. The aim of this study is to describe the development and the validation process of this device. METHODS: We developed the 3D HAS combining a physical heart model with an EAM system. This simulator was then validated by ten electrophysiologists subdivided in two groups based on their experience in electrophysiology procedures...
September 17, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/30225447/comorbidities-fragility-and-quality-of-life-in-heart-failure-patients-with-midrange-ejection-fraction
#16
Paloma Gastelurrutia, Josep Lupón, Pedro Moliner, Xiaobo Yang, German Cediel, Marta de Antonio, Mar Domingo, Salvador Altimir, Beatriz González, Margarita Rodríguez, Carmen Rivas, Violeta Díaz, Erik Fung, Elisabet Zamora, Javier Santesmases, Julio Núñez, Jean Woo, Antoni Bayes-Genis
Objective: To assess the effects of comorbidities, fragility, and quality of life (QOL) on long-term prognosis in ambulatory patients with heart failure (HF) with midrange left ventricular ejection fraction (HFmrEF), an unexplored area. Patients and Methods: Consecutive patients prospectively evaluated at an HF clinic between August 1, 2001, and December 31, 2015, were retrospectively analyzed on the basis of left ventricular ejection fraction category. We compared patients with HFmrEF (n=185) to those with reduced (HFrEF; n=1058) and preserved (HFpEF; n=162) ejection fraction...
June 2018: Mayo Clinic proceedings. Innovations, quality & outcomes
https://www.readbyqxmd.com/read/30225419/family-help-with-medication-management-a-predictive-marker-for-early-readmission
#17
Magali P Disdier Moulder, Jenna M Larock, Adrian Garofoli, David A Foley
Objectives: To identify aspects of medication management that are associated with a greater risk of hospital readmission. Patients and Methods: We conducted a prospective cohort study, with a thorough medication history and reconciliation performed at admission and discharge. Patients 18 years or older (N=258) were prospectively enrolled on admission to a cardiology service at a tertiary care hospital from September 1, 2011, through July 31, 2012. All patients received their hospital and outpatient care within our institution, which minimized loss to follow-up...
December 2017: Mayo Clinic proceedings. Innovations, quality & outcomes
https://www.readbyqxmd.com/read/30223014/fidelity-and-feasibility-of-a-brief-emergency-department-intervention-to-empower-adults-with-serious-illness-to-initiate-advance-care-planning-conversations
#18
Richard E Leiter, Miryam Yusufov, Mohammad Adrian Hasdianda, Lauren A Fellion, Audrey C Reust, Susan D Block, James A Tulsky, Kei Ouchi
CONTEXT: Emergency Department (ED) visits provide opportunities to empower patients to discuss advance care planning (ACP) with their outpatient clinicians, but systematically developed, feasible interventions do not currently exist. Brief negotiated interview (BNI) interventions, which allow ED clinicians to efficiently motivate patients, have potential to meet this need. OBJECTIVES: We developed a BNI ED intervention to empower older adults with life-limiting illness to formulate and communicate medical care goals to their primary outpatient clinicians...
September 14, 2018: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/30222660/predictors-of-mortality-among-hospitalized-patients-with-lower-respiratory-tract-infections-in-a-high-hiv-burden-setting
#19
William Worodria, Chang Emily, Alfred Andama, Ingvar Sanyu, Patrick Byanyima, Emmanuel Musisi Bblt, Sylvia Kaswabuli, Josephine Zawedde, Irene Ayakaka, Abdul Sessolo, Rejani Lalitha, John Lucian Davis, Laurence Huang
IntroductionLower respiratory tract infections (LRTIs) are a leading cause of mortality in sub-Saharan Africa. Triaging identifies patients at high-risk of death but laboratory tests proposed for use in severity-of-illness scores are not readily available, limiting their clinical use. Our objective was to determine whether baseline characteristics in hospitalized participants with LRTI predicted increased risk of death.MethodsThis was a secondary analysis from the MIND-IHOP cohort of adults hospitalized with LRTI who underwent standardized investigations and treatment...
September 14, 2018: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/30221553/safety-and-efficacy-of-propofol-anesthesia-for-pediatric-target-controlled-infusion-in-children-below-3-years-of-age-a-retrospective-observational-study
#20
Pyoyoon Kang, Young-Eun Jang, Eun-Hee Kim, Ji-Hyun Lee, Jin-Tae Kim, Hee-Soo Kim
BACKGROUND: Although the requirement of propofol in children is increasing, propofol for induction and maintenance of anesthesia below 3 years old has not been approved in Korea. This study can provide a clinical evidence to increase the range of approval. RESEARCH DESIGN AND METHODS: We reviewed the medical records of patients below 3 years of age who underwent surgery between September 2013 and December 2016. Safety was evaluated on the basis of vital signs, and laboratory findings and efficacy were evaluated on the basis of the bispectral index (BIS)...
September 15, 2018: Expert Opinion on Drug Safety
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