keyword
https://read.qxmd.com/read/38652672/time-to-event-genome-wide-association-study-for-incident-cardiovascular-disease-in-people-with-type-2-diabetes
#1
JOURNAL ARTICLE
Soo Heon Kwak, Ryan B Hernandez-Cancela, Daniel A DiCorpo, David E Condon, Jordi Merino, Peitao Wu, Jennifer A Brody, Jie Yao, Xiuqing Guo, Fariba Ahmadizar, Mariah Meyer, Murat Sincan, Josep M Mercader, Sujin Lee, Jeffrey Haessler, Ha My T Vy, Zhaotong Lin, Nicole D Armstrong, Shaopeng Gu, Noah L Tsao, Leslie A Lange, Ningyuan Wang, Kerri L Wiggins, Stella Trompet, Simin Liu, Ruth J F Loos, Renae Judy, Philip H Schroeder, Natalie R Hasbani, Maxime M Bos, Alanna C Morrison, Rebecca D Jackson, Alexander P Reiner, JoAnn E Manson, Ninad S Chaudhary, Lynn K Carmichael, Yii-Der Ida Chen, Kent D Taylor, Mohsen Ghanbari, Joyce van Meurs, Achilleas N Pitsillides, Bruce M Psaty, Raymond Noordam, Ron Do, Kyong Soo Park, J Wouter Jukema, Maryam Kavousi, Adolfo Correa, Stephen S Rich, Scott M Damrauer, Catherine Hajek, Nam H Cho, Marguerite R Irvin, James S Pankow, Girish N Nadkarni, Robert Sladek, Mark O Goodarzi, Jose C Florez, Daniel I Chasman, Susan R Heckbert, Charles Kooperberg, Josée Dupuis, Rajeev Malhotra, Paul S de Vries, Ching-Ti Liu, Jerome I Rotter, James B Meigs
OBJECTIVE: To identify genetic risk factors for incident cardiovascular disease (CVD) among people with type 2 diabetes (T2D). RESEARCH DESIGN AND METHODS: We conducted a multiancestry time-to-event genome-wide association study for incident CVD among people with T2D. We also tested 204 known coronary artery disease (CAD) variants for association with incident CVD. RESULTS: Among 49,230 participants with T2D, 8,956 had incident CVD events (event rate 18...
April 23, 2024: Diabetes Care
https://read.qxmd.com/read/38651973/self-care-trajectories-of-patients-with-coronary-heart-disease-a-longitudinal-observational-study
#2
JOURNAL ARTICLE
Brynja Ingadóttir, Margrét Hrönn Svavarsdóttir, Corrine Y Jurgens, Christopher S Lee
AIMS: To determine if distinct trajectories of coronary heart disease (CHD) self-care behaviours could be identified, linked to differences in quality of life (QoL), and predicted based on baseline characteristics. METHODS AND RESULTS: A secondary analysis of a prospective, longitudinal, observational study. Patients with CHD answered questionnaires at study enrolment and six months later: Self-Care of Coronary Heart Disease Inventory (three subscales: maintenance, management and confidence, scored 0-100, higher score = better self-care), Hospital Anxiety and Depression Scale, 12-Item Short Form Survey, 16-Item European Health Literacy Survey Questionnaire, CHD Education Questionnaire...
April 23, 2024: European Journal of Cardiovascular Nursing
https://read.qxmd.com/read/38651382/modified-frailty-index-associates-with-transoral-robotic-surgery-complications-and-survival-a-national-database-study
#3
JOURNAL ARTICLE
Amiti Jain, Zachary N Goldberg, Erin Briggs, Dev R Amin, Zachary D Urdang, Richard A Goldman, David M Cognetti, Joseph M Curry
OBJECTIVE: The modified frailty index (mFI-5) is a National Surgical Quality Improvement Program-derived 5-factor index that has been proven to reflect frailty and predict morbidity and mortality. We hypothesize that mFI-5 is a valid predictive measure in the transoral robotic surgery (TORS) population. METHODS: Retrospective study utilizing the TriNetX US-collaborative health records network querying for TORS patients. Cohorts were stratified by mFI-5 score which uses five ICD-10 codes: nonindependent functional status, hypertension, obstructive respiratory disease, heart failure, and diabetes mellitus...
April 23, 2024: Laryngoscope
https://read.qxmd.com/read/38651225/outcomes-of-concomitant-maze-procedure-in-tricuspid-repair-for-severe-tricuspid-regurgitation
#4
JOURNAL ARTICLE
Ilkun Park, Suryeun Chung, Yang Hyun Cho, Kiick Sung, Wook Sung Kim, Kyungsub Song, Joong Hyun Ahn, Chang Seok Jeon, Pyo Won Park, Dong Seop Jeong
BACKGROUND: We aimed to analyze the impact of concomitant Maze procedure on the clinical and rhythm outcomes, and echocardiographic parameters in tricuspid repair for patients with severe tricuspid regurgitation (TR) and persistent atrial fibrillation (AF). METHODS: Patients who had severe TR and persistent AF and underwent tricuspid valve (TV) repair were included in the study. Both primary TR and secondary TR were included in the current study. The study population was stratified according to Maze procedure...
April 22, 2024: Journal of Korean Medical Science
https://read.qxmd.com/read/38650867/association-between-life-s-essential-8-and-cognitive-function-insights-from-nhanes-2011-2014
#5
JOURNAL ARTICLE
Kangni Liang, Xiaoling Zhang
INTRODUCTION: Life's Essential 8 (LE8) is prompted by the American Heart Association (AHA) to assess cardiovascular health. The association between LE8 and cognitive function in America is unknown. Our study was to investigate the association of LE8 with cognitive function in general adults. MATERIALS AND METHODS: A total of 2,301 participants were enrolled in the National Health and Nutrition Examination Surveys (NHANES). LE8 scores (range 0-100) were obtained from measurements based on American Heart Association definitions, divided into health behavior and health factor scores...
2024: Frontiers in Aging Neuroscience
https://read.qxmd.com/read/38650792/impact-of-clinical-and-sociodemographic-factors-on-quality-of-life-following-coronary-artery-bypass-grafting-a-mixed-methods-study
#6
JOURNAL ARTICLE
Abdulmajeed A Alzahrani, Abdullah K AlAssiri, Khalid E Al-Ebrahim, Zeyad T Ganbou, Meshal M Alsudais, Abdulmajeed M Khafagy
INTRODUCTION: Coronary artery bypass grafting (CABG) is an essential surgical management modality for patients with coronary artery disease. Health-related quality of life (HRQoL) has become important because of the significant decrease in the mortality rate associated with CABG. We aimed to explore the factors that affect the quality of life after CABG. METHODS: This study used a descriptive correlational design to assess the determinants of HRQoL using the 36-item Short Form Health Survey questionnaire (SF-36)...
March 2024: Curēus
https://read.qxmd.com/read/38649940/comparison-between-high-flow-nasal-oxygen-hfno-alternated-with-non-invasive-ventilation-niv-and-hfno-and-niv-alone-in-patients-with-covid-19-a-retrospective-cohort-study
#7
JOURNAL ARTICLE
Amanda Pereira da Cruz, Gloria Martins, Camila Marinelli Martins, Victoria Marques, Samantha Christovam, Denise Battaglini, Chiara Robba, Paolo Pelosi, Patricia Rieken Macedo Rocco, Fernanda Ferreira Cruz, Cynthia Dos Santos Samary, Pedro Leme Silva
BACKGROUND: Non-invasive respiratory support (conventional oxygen therapy [COT], non-invasive ventilation [NIV], high-flow nasal oxygen [HFNO], and NIV alternated with HFNO [NIV + HFNO] may reduce the need for invasive mechanical ventilation (IMV) in patients with COVID-19. The outcome of patients treated non-invasively depends on clinical severity at admission. We assessed the need for IMV according to NIV, HFNO, and NIV + HFNO in patients with COVID-19 according to disease severity and evaluated in-hospital survival rates and hospital and intensive care unit (ICU) lengths of stay...
April 22, 2024: European Journal of Medical Research
https://read.qxmd.com/read/38649900/very-short-sleep-duration-reveals-a-proteomic-fingerprint-that-is-selectively-associated-with-incident-diabetes-mellitus-but-not-with-incident-coronary-heart-disease-a-cohort-study
#8
JOURNAL ARTICLE
Thomas Svensson, Akiko Kishi Svensson, Mariusz Kitlinski, Gunnar Engström, Jan Nilsson, Marju Orho-Melander, Peter M Nilsson, Olle Melander
BACKGROUND: The molecular pathways linking short and long sleep duration with incident diabetes mellitus (iDM) and incident coronary heart disease (iCHD) are not known. We aimed to identify circulating protein patterns associated with sleep duration and test their impact on incident cardiometabolic disease. METHODS: We assessed sleep duration and measured 78 plasma proteins among 3336 participants aged 46-68 years, free from DM and CHD at baseline, and identified cases of iDM and iCHD using national registers...
April 23, 2024: BMC Medicine
https://read.qxmd.com/read/38649640/simultaneous-transapical-transcatheter-aortic-and-mitral-valve-replacement-in-patients-with-severe-valve-dysfunction-initial-experience
#9
JOURNAL ARTICLE
Jiawei Zhou, Yuehuan Li, JianGang Wang, Haibo Zhang
BACKGROUND: Simultaneous transcatheter mitral valve in valve (VIV) replacement and aortic valve replacement experience is limited. We report our initial experience with simultaneous transapical transcatheter aortic and mitral valve replacement in patients with severe valve dysfunction. METHODS: A total of 8 patients had simultaneous transcatheter heart valve implants for severe mitral bioprosthesis failure (VIV), with a second valve procedure that included native aortic regurgitation (n = 3) or degenerated bioprostheses in the aortic position (n = 5)...
April 22, 2024: General Thoracic and Cardiovascular Surgery
https://read.qxmd.com/read/38649527/relationship-between-cachexia-and-short-physical-performance-battery-scores-in-patients-with-heart-failure-attending-comprehensive-outpatient-cardiac-rehabilitation
#10
JOURNAL ARTICLE
Michitaka Kato, Shintaro Ono, Hiromasa Seko, Kazuya Kito, Toshiya Omote, Mayuko Omote, Yoshihiro Seo, Shingo Omote
Heart failure (HF) can cause metabolic imbalances, leading to anabolic resistance and increased energy expenditure, which often results in weight loss and cachexia. Comprehensive cardiac rehabilitation (CR), including exercise, nutritional support, and risk management, is crucial for enhancing the health and quality of life of patients with HF and is expected to play a central role in the prevention and treatment of HF-associated cachexia. However, the prevalence of cachexia in patients with HF undergoing comprehensive outpatient CR is currently unknown, and the detailed characteristics including of motor function of such patients remain undefined...
April 22, 2024: Heart and Vessels
https://read.qxmd.com/read/38648801/open-water-swimming-in-elite-triathletes-physiological-and-biomechanical-determinants
#11
JOURNAL ARTICLE
Óscar López-Belmonte, Ana Gay, Jesús J Ruiz-Navarro, Francisco Cuenca-Fernández, Roberto Cejuela, Raúl Arellano
This study aimed (i) to analyze the 1500 m open water swimming performance, (ii) to examine the associations between physiological and biomechanical variables with swimming performance, and (iii) to determine which variables can predict swimming performance in triathletes. Fourteen elite triathletes (23.4±3.8 y) performed a 1500 m test in open water swimming conditions. Swimming performance was assessed using World Aquatics Points Scoring, and data were obtained from the 1500 m open water swimming test...
April 22, 2024: International Journal of Sports Medicine
https://read.qxmd.com/read/38648098/chatgpt-s-performance-in-cardiac-arrest-and-bradycardia-simulations-using-the-american-heart-association-s-advanced-cardiovascular-life-support-guidelines-exploratory-study
#12
JOURNAL ARTICLE
Cecilia Pham, Romi Govender, Salik Tehami, Summer Chavez, Omolola E Adepoju, Winston Liaw
BACKGROUND: ChatGPT is the most advanced large language model to date, with prior iterations having passed medical licensing examinations, providing clinical decision support, and improved diagnostics. Although limited, past studies of ChatGPT's performance found that artificial intelligence could pass the American Heart Association's advanced cardiovascular life support (ACLS) examinations with modifications. ChatGPT's accuracy has not been studied in more complex clinical scenarios...
April 22, 2024: Journal of Medical Internet Research
https://read.qxmd.com/read/38645727/acute-physiological-biomechanical-and-perceptual-responses-of-runners-wearing-downward-curved-carbon-fiber-insoles
#13
JOURNAL ARTICLE
Florian A Engel, Frank Zehnter, Tomer Yona, Patrick Mai, Steffen Willwacher, Peter Düking, Billy Sperlich
In a randomized controlled cross-over study ten male runners (26.7 ± 4.9 years; recent 5-km time: 18:37 ± 1:07 min:s) performed an incremental treadmill test (ITT) and a 3-km time trial (3-km TT) on a treadmill while wearing either carbon fiber insoles with downwards curvature or insoles made of butyl rubber (control condition) in light road racing shoes (Saucony Fastwitch 9). Oxygen uptake, respiratory exchange ratio, heart rate, blood lactate concentration, stride frequency, stride length and time to exhaustion were assessed during ITT...
2024: Frontiers in sports and active living
https://read.qxmd.com/read/38644069/management-and-outcomes-of-pregnant-women-with-cardiovascular-diseases-in-a-cardio-obstetric-team
#14
JOURNAL ARTICLE
Marjorie Richardson, Jean Philippe Bonnet, Capucine Coulon, Olivia Domanski, Benjamin Constans, Max Gonzalez Estevez, Sophie Gautier, Luisa Marsili, Yasmine Ould Hamoud, Augustin Coisne, Hélène Ridon, Anne-Sophie Polge, Stéphanie Mouton, Yasmine Haddad, Francis Juthier, Mouhamed Moussa, Claire Mounier Vehier, Gilles Lemesle, Guillaume Schurtz, Charles Garabedian, Mercedes Jourdain, Sandro Ninni, François Brigadeau, David Montaigne, Nicolas Lamblin, Louise Ghesquiere
BACKGROUND: Cardiovascular diseases (CVDs) are currently the leading cause of maternal death in Western countries. Although multidisciplinary cardio-obstetric teams are recommended to improve the management of pregnant women with CVD, data supporting this approach are scarce. AIMS: To describe the characteristics and outcomes of pregnant patients with CVD managed within the cardio-obstetric programme of a tertiary centre. METHODS: We included every pregnant patient with history of CVD managed by our cardio-obstetric team between June 2017 and December 2019, and collected all major cardiovascular events (death, heart failure, acute coronary syndromes, stroke, endocarditis and aortic dissection) that occurred during pregnancy, peripartum and the following year...
April 12, 2024: Archives of Cardiovascular Diseases
https://read.qxmd.com/read/38643935/rome-iii-criteria-capture-higher-irritable-bowel-syndrome-snp-heritability-and-highlight-a-novel-genetic-link-with-cardiovascular-traits
#15
JOURNAL ARTICLE
Leticia Camargo Tavares, Esteban Alexander Lopera-Maya, Ferdinando Bonfiglio, Tenghao Zheng, Trishla Sinha, Francine Zanchetta Marques, Alexandra Zhernakova, Serena Sanna, Mauro D'Amato
BACKGROUND & AIMS: Irritable bowel syndrome (IBS) shows genetic predisposition, and large-scale genome-wide association studies (GWAS) are emerging, based on heterogeneous disease definitions. We aimed at investigating the genetic architecture of IBS defined according to gold-standard Rome Criteria. METHODS: We conducted GWAS meta-analyses of Rome III IBS and its subtypes in 24,735 IBS cases and 77,149 asymptomatic controls from two independent European cohorts (UK Biobank and Lifelines)...
April 18, 2024: Cellular and Molecular Gastroenterology and Hepatology
https://read.qxmd.com/read/38643925/optimal-method-for-assessing-right-ventricular-to-pulmonary-arterial-coupling-and-subclinical-right-ventricular-dysfunction-in-older-aged-healthy-adults-the-multi-ethnic-study-of-atherosclerosis
#16
JOURNAL ARTICLE
Vivek P Jani, Jordan B Strom, Abhishek Gami, Lauren Beussink-Nelson, Ravi Patel, Erin D Michos, Sanjiv J Shah, Benjamin H Freed, Monica Mukherjee
BACKGROUND: Right ventricular (RV) to pulmonary arterial (PA) coupling describes the ability of the RV to augment contractility in response to increased afterload. Several echocardiographic indexes of RV-PA coupling have been defined; however, the optimal numerator in the coupling ratio is unclear. We sought to establish which of these ratios is best for assessing RV-PA coupling based on their relationships with 6-minute walk distance (6MWD), N-terminal pro-B-type natriuretic peptide (NT-proBNP), and the Kansas City Cardiomyopathy Questionnaire (KCCQ) in aging adults...
April 19, 2024: American Journal of Cardiology
https://read.qxmd.com/read/38643303/post-stroke-arrhythmia-could-be-a-potential-predictor-for-post-stroke-depression
#17
JOURNAL ARTICLE
Tao Xu, Fangying Dong, Muhua Zhang, Kewu Wang, Tian Xu, Shudong Xia, Chao Feng
Post-stroke depression (PSD) is regarded as the consequence of multiple contributors involving the process of cognition, mood and autonomic system, with the specific mechanism unclear yet. As a common type of stroke-heart syndromes, post-stroke arrhythmia shared some common pathogenesis with PSD. We presumed that post-stroke arrhythmia might be an early distinguishable marker for the presence of PSD and aimed to verity their association in this study. Patients with first-ever ischemic stroke were enrolled. The presence of post-stroke ectopic arrhythmia and the symptoms of arrhythmia were recorded with anti-arrhythmia drugs prescribed when necessary...
April 20, 2024: Scientific Reports
https://read.qxmd.com/read/38642391/charlson-comorbidity-index-and-the-severity-of-community-acquired-pneumonia-caused-by-sars-cov-2-a-retrospective-analysis
#18
JOURNAL ARTICLE
Mariya Marushchak, Inna Krynytska, Tetiana Homeliuk, Andriy Vayda, Sviatoslav Kostiv, Vasyl Blikhar
BACKGROUND: The Charlson comorbidity index (CCI) has been considered as a valid and reliable tool for predicting poor clinical outcomes and mortality in patients with coronavirus disease 2019 (COVID-19). However, its relationship with the severity of pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has not been thoroughly explored. OBJECTIVES: The aim of the present study was to identify the impact of the comorbidity burden, quantitatively assessed by applying CCI, on the severity of inpatient community-acquired pneumonia (CAP) caused by SARS-CoV-2...
2024: Dental and Medical Problems
https://read.qxmd.com/read/38641904/prognostic-value-of-growth-differentiation-factor-15-in-heart-failure-among-whole-ejection-fraction-phenotypes
#19
JOURNAL ARTICLE
Lyu Lyu, Juan Xu, Cui Xv, Hunan Xiao, Zhenzhen Liu, Yanru He, Weiyang Gao, Benchuan Hao, Hongbin Liu
AIMS: The utility of growth differentiation factor-15 (GDF-15) in predicting long-term adverse outcomes in heart failure (HF) patients is not well established. This study explored the relationship between GDF-15 levels and adverse outcomes in HF patients across various ejection fraction (EF) phenotypes associated with coronary heart disease (CHD) and evaluated the added prognostic value of incorporating GDF-15 into the Meta-Analysis Global Group in Chronic Heart Failure (MAGGIC) risk score-based model...
April 19, 2024: ESC Heart Failure
https://read.qxmd.com/read/38641856/ninety-day-stroke-recurrence-in-minor-stroke-systematic-review-and-meta-analysis-of-trials-and-observational-studies
#20
JOURNAL ARTICLE
Andy Lim, Henry Ma, S Claiborne Johnston, Shaloo Singhal, Subramanian Muthusamy, Yongjun Wang, Yuesong Pan, Shelagh B Coutts, Michael D Hill, Angel Ois, Moira K Kapral, Michael Knoflach, Lisa J Woodhouse, Philip M Bath, Thanh G Phan
BACKGROUND: Risk of recurrence after minor ischemic stroke is usually reported with transient ischemic attack. No previous meta-analysis has focused on minor ischemic stroke alone. The objective was to evaluate the pooled proportion of 90-day stroke recurrence for minor ischemic stroke, defined as a National Institutes of Health Stroke Scale severity score of ≤5. METHODS AND RESULTS: Published papers found on PubMed from 2000 to January 12, 2021, reference lists of relevant articles, and experts in the field were involved in identifying relevant studies...
April 19, 2024: Journal of the American Heart Association
keyword
keyword
109446
1
2
Fetch more papers »
Fetching more papers... Fetching...
Remove bar
Read by QxMD icon Read
×

Save your favorite articles in one place with a free QxMD account.

×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"

We want to hear from doctors like you!

Take a second to answer a survey question.