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bacteremia guidelines

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https://www.readbyqxmd.com/read/29780851/top-questions-in-uncomplicated-non-staphylococcus-aureus-bacteremia
#1
Jesse D Sutton, Sena Sayood, Emily S Spivak
The Infectious Diseases Society of America infection-specific guidelines provide limited guidance on the management of focal infections complicated by secondary bacteremias. We address the following 3 commonly encountered questions and management considerations regarding uncomplicated bacteremia not due to Staphylococcus aureus : the role and choice of oral antibiotics focusing on oral beta-lactams, the shortest effective duration of therapy, and the role of repeat blood cultures.
May 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29570493/does-anthrax-antitoxin-therapy-have-a-role-in-the-treatment-of-inhalational-anthrax
#2
Nicholas J Vietri
PURPOSE OF REVIEW: Inhalational anthrax is a rare disease and Bacillus anthracis is a likely pathogen to be used in a biological attack. The lack of clinical experience with anthrax has led experts to develop treatment guidelines. These guidelines recommend anthrax antitoxin to be used in conjunction with antibiotics for the treatment of patients with systemic anthrax infection, yet there is still a lack of human or animal data to support this recommendation. RECENT FINDINGS: The U...
March 22, 2018: Current Opinion in Infectious Diseases
https://www.readbyqxmd.com/read/29511408/worsening-of-acute-cholangitis-caused-by-a-bile-duct-stone-after-hospitalization-a-case-series
#3
Tetsuro Akashi, Yuichi Tachibana, Susumu Matsuo, Junya Gibo
Acute cholangitis is a fatal condition if inadequately treated. It is possible to underestimate the severity of the condition because bacterial cultures are not immediately available. We evaluated the clinical features of patients with cholangitis due to bile duct stones who were diagnosed with severe bacteremia at the time of hospitalization, but not at the time of the initial visit. We conducted a retrospective analysis of cases of endoscopic retrograde cholangiopancreatography performed between January 2007 and October 2011 in patients with bile duct stones complicated by cholangitis...
February 2018: Gastroenterology Research
https://www.readbyqxmd.com/read/29506430/pregnancy-and-hemodialysis-access-a-case-for-patient-satisfaction-in-favor-of-a-tunneled-dialysis-catheter
#4
Sushil Mehandru, Attiya Haroon, Avais Masud, Mayurkumar Patel, Elmer Sadiang-Abay, Eric J Costanzo, Tushar J Vachharajani
While an arteriovenous fistula is the best available access, many patients continue to rely on a tunneled hemodialysis catheter for dialysis therapy. Despite the highest risk of catheter-related bacteremia and associated morbidity and mortality, patients often prefer tunneled hemodialysis catheter to avoid pain associated with cannulation of an arteriovenous access. We report three tunneled hemodialysis catheter-dependent end-stage renal disease patients (age: 38, 35, 33 years), who became pregnant. Pregnancy was discovered at 10, 12 and 10 weeks of gestation...
March 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29460786/appropriateness-of-peripheral-parenteral-nutrition-use-in-adult-patients-at-an-academic-medical-center
#5
David Sugrue, Andrew S Jarrell, Rachel Kruer, Stephanie Davis, Dachelle Johnson, Evelyn Tsui, Sukyee Snyder, Jessica Crow
BACKGROUND & AIMS: Current evidence and guidelines identify patient populations who may benefit from parenteral nutrition. Peripheral parenteral nutrition (PPN) may be indicated for a subset of patients; however, PPN therapy carries a risk of associated adverse effects. The purpose of this project was to assess appropriateness of current PPN prescribing practices at an academic medical center to determine whether additional guidance and oversight may be beneficial. METHODS: Adult patients admitted from August 1, 2015 to November 30, 2015 with at least one order of PPN administered were included...
February 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29451055/early-discontinuation-of-empirical-antibacterial-therapy-in-febrile-neutropenia-the-antibiostop-study
#6
Lenaïg Le Clech, Jean-Philippe Talarmin, Marie-Anne Couturier, Jean-Christophe Ianotto, Christophe Nicol, Ronan Le Calloch, Stéphanie Dos Santos, Pascal Hutin, Didier Tandé, Virginie Cogulet, Christian Berthou, Gaëlle Guillerm
INTRODUCTION: Immediate empirical antibiotic therapy is mandatory in febrile chemotherapy-induced neutropenia, but its optimal duration is unclear, especially in patients with fever of unknown origin (FUO). OBJECTIVES: The primary objective of this 20-month prospective observational study was to evaluate the feasibility and safety of short-term antibiotic treatment in afebrile or febrile patients exhibiting FUO, irrespective of their neutrophil count. The secondary objective was to describe the epidemiology of all episodes of febrile neutropenia...
February 16, 2018: Infectious Diseases
https://www.readbyqxmd.com/read/29324478/site-of-entry-and-surgical-timing-in-infective-endocarditis
#7
Francesco Bovenzi, Lucia Borelli, Lauro Cortigiani
No abstract text is available yet for this article.
February 2018: Journal of Cardiovascular Medicine
https://www.readbyqxmd.com/read/29323086/a-rare-case-of-shewanella-putrefaciens-bacteremia-in-a-patient-of-road-traffic-accident
#8
Ritesh Ranjan, Priti Chowdhary
Shewanella putrefaciens rarely causes human infection. These are mostly found in environment and food stuffs. Shewanella are often found in mixed culture. It has been implicated in cellulitis, otitis media, and septicemia. It may be found in respiratory tract, urine, feces, and pleural fluid. There is no definite guideline for therapeutic option. In general, these are susceptible to various antimicrobial agents but are often resistant to penicillin and cephalothin. We report a rare case of bacteremia by S. putrefaciens in a patient of head injury with polytrauma after a road traffic accident...
October 2017: Indian Journal of Pathology & Microbiology
https://www.readbyqxmd.com/read/29319209/effectiveness-of-antibacterial-prophylaxis-during-induction-chemotherapy-in-children-with-acute-lymphoblastic-leukemia
#9
M L Sulis, T M Blonquist, K E Stevenson, S K Hunt, S Kay-Green, U H Athale, L A Clavell, P D Cole, K M Kelly, C Laverdiere, J M Leclerc, B Michon, M A Schorin, J G Welch, D S Neuberg, S E Sallan, L B Silverman
BACKGROUND: Pediatric patients receiving induction chemotherapy for newly diagnosed acute lymphoblastic leukemia (ALL) are at high risk of developing life-threatening infections. We investigated whether uniform antibacterial guidelines, including mandatory antibacterial prophylaxis in afebrile patients during induction, decreases the incidence of microbiologically documented bacteremia. METHODS: Between 2012 and 2015, 230 patients with newly diagnosed ALL (aged 1-21) were enrolled on Dana-Farber Cancer Institute ALL Consortium Protocol 11-001 (DFCI 11-001)...
May 2018: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29298323/implementation-of-global-antimicrobial-resistance-surveillance-system-glass-in-patients-with-bacteremia
#10
Rujipas Sirijatuphat, Kantarida Sripanidkulchai, Adhiratha Boonyasiri, Pinyo Rattanaumpawan, Orawan Supapueng, Pattarachai Kiratisin, Visanu Thamlikitkul
The global antimicrobial resistance surveillance system (GLASS) was launched by the World Health Organization (WHO) in 2015. GLASS is a surveillance system for clinical specimens that are sent to microbiology laboratory for clinical purposes. The unique feature of GLASS is that clinical data is combined with microbiological data, and deduplication of the microbiological results is performed. The objective of the study was to determine feasibility and benefit of GLASS for surveillance of blood culture specimens...
2018: PloS One
https://www.readbyqxmd.com/read/29238587/bacterial-infections-in-acute-variceal-hemorrhage-despite-antibiotics-a-multicenter-study-of-predictors-and-clinical-impact
#11
Stephen Lee, Lynora Saxinger, Mang Ma, Verónica Prado, Joaquin Fernández, Deepali Kumar, Juan Gonzalez-Abraldes, Adam Keough, Ravin Bastiampillai, Michelle Carbonneau, Javier Fernandez, Puneeta Tandon
Background and aims: Current guidelines recommend antibiotic prophylaxis in all patients presenting with cirrhosis and acute variceal hemorrhage (AVH). We aimed to evaluate the characteristics and clinical impact of "early" infections (developing within 14 days) of AVH in a real-world setting. Methods: We analyzed retrospective data from a cohort of 371 adult patients with cirrhosis and AVH all of whom had received antibiotic prophylaxis (74% men; mean age 56 years), admitted to tertiary care hospitals in Edmonton, Alberta, Canada, and Barcelona, Spain...
December 2017: United European Gastroenterology Journal
https://www.readbyqxmd.com/read/29235661/association-of-higher-daptomycin-dose-7-mg-kg-or-greater-with-improved-survival-in-patients-with-methicillin-resistant-staphylococcus-aureus-bacteremia
#12
Tristan T Timbrook, Aisling R Caffrey, Megan K Luther, Vrishali Lopes, Kerry L LaPlante
STUDY OBJECTIVE: Current guidelines recommend higher daptomycin doses than the daptomycin label dose of 6 mg/kg for methicillin-resistant Staphylococcus aureus (MRSA) bacteremia; however, the evidence supporting this recommendation is from in vitro and case series studies. This study evaluated the comparative effectiveness of the daptomycin label dose versus higher daptomycin doses in patients with MRSA bacteremia. DESIGN: Retrospective national cohort study. SETTING: Veterans Affairs medical centers...
February 2018: Pharmacotherapy
https://www.readbyqxmd.com/read/29123448/new-case-of-endotipsitis-urgent-need-for-clinical-practice-guidelines
#13
Alberto Garcia-Zamalloa, Jorge Taboada Gomez, Agustín Castiella Egusquiza
Transjugular intrahepatic portosystemic shunt (TIPS) is a minimally invasive procedure used for the decompression of portal pressure since the early 1990s. Bacteremia with an infection of the TIPS or endotipsitis is a serious complication with 32% mortality. To date and including the present case, only 56 cases have been reported in the literature. There are concerns regarding underdiagnosis. We report a case of a patient with endotipsitis and recurrent bacteremia treated successfully in our institution. In addition, previous reported cases were reviewed regarding microbiological data and mortality...
October 2017: Eurasian Journal of Medicine
https://www.readbyqxmd.com/read/29076932/evaluation-of-the-clinical-utility-of-a-real-time-pcr-assay-for-the-diagnosis-of-streptococcus-pneumoniae-bacteremia-in-children-a-retrospective-diagnostic-accuracy-study
#14
Jane Murphy, Sadhbh O' Rourke, Mary Corcoran, Nicola O' Sullivan, Robert Cunney, Richard Drew
BACKGROUND: The widespread uptake of pneumococcal vaccines has substantially reduced the incidence of invasive pneumococcal disease, such that pneumococcal bacteremia in children is now considered a relatively rare event. The objective of this study was to ascertain the clinical utility of a Streptococcus pneumoniae real-time polymerase chain reaction (PCR) assay compared with standard blood culture for the diagnosis of pneumococcal bacteremia in children in the post-vaccine era. METHODS: A systematic retrospective review of laboratory and patient records from Children's University Hospital, Temple Street, during a 6-year period was performed...
February 2018: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/29065784/effect-of-vancomycin-initial-dosing-on-time-to-systemic-inflammatory-response-syndrome-resolution-in-patients-with-methicillin-resistant-staphylococcus-aureus-bacteremia
#15
Jessica Lynn Wesolek, Kelly McNorton, George Delgado, Christopher Alan Giuliano
Current guidelines suggest using vancomycin-loading doses for complicated infections despite a lack of evidence to support this practice. To address this gap, we performed a single-centre cohort study of 124 patients with sepsis due to methicillin-resistant Staphylococcus aureus bacteremia. Patients were allocated into two groups based on initial dose of vancomycin, <20 mg/kg or ≥20 mg/kg, and evaluated for time to resolution of systemic inflammatory response syndrome (SIRS). Among a cohort of 124 patients, 87 received vancomycin initial doses <20 mg/kg and 37 received ≥20 mg/kg...
April 2018: Journal of Chemotherapy
https://www.readbyqxmd.com/read/29026535/clinical-and-molecular-characteristics-risk-factors-and-outcomes-of-carbapenem-resistant-klebsiella-pneumoniae-bloodstream-infections-in-the-intensive-care-unit
#16
Xia Zheng, Jian-Feng Wang, Wang-Lan Xu, Jun Xu, Juan Hu
BACKGROUND: To analyze the clinical characteristics and outcomes of carbapenem-resistant Klebsiella pneumoniae (CRKp) and carbapenem-susceptible K. pneumoniae (CSKp) bloodstream infections (BSIs), and to study the risk factors for development of CRKp BSI and K. pneumoniae BSI-related mortality. METHODS: A retrospective case control study of patients with K. pneumoniae BSI was conducted in the intensive care unit of the First Affiliated Hospital, Medical of College, Zhejiang University from January 2013 to December 2014...
2017: Antimicrobial Resistance and Infection Control
https://www.readbyqxmd.com/read/28934715/stercoral-perforation-of-the-rectosigmoid-colon-due-to-chronic-constipation-a-case-report
#17
Mustafa Fevzi Celayir, Hakan Mustafa Köksal, Mehmet Uludag
INTRODUCTION: Chronic constipation is very common in elderly patients. As a result of this situation fecaloma is also frequently seen at these ages. However, the stercoral perforation caused by fecaloma is a rare situation to occur. The rectosigmoid colon is the most affected colonic segment. It is seen in older patients with concomitant diseases and a low quality of life. PRESENTATION OF CASE: Here in this case, we have to report an 83 - year-old male patient who came to the emergency room with complaints of abdominal pain and constipation for two days...
2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28925912/epidemiologic-features-of-invasive-group-a-streptococcus-infection-in-a-rural-hospital-6-year-retrospective-report-and-literature-review
#18
Kassandra Loewen, Natalie Bocking, Cai-Lei Matsumoto, Mike Kirlew, Len Kelly
INTRODUCTION: High rates of invasive group A Streptococcus disease were suspected by clinicians in northwestern Ontario. Patients with sepsis were being encountered with bacteremia positive for group A Streptococcus. This study was designed to assess the incidence of invasive group A Streptococcus infection in the region and provide best-practice treatment information. METHODS: We performed a retrospective chart review at the Sioux Lookout Meno Ya Win Health Centre (SLMHC) from 2009 to 2014 to examine rates of infection due to invasive group A Streptococcus and outcomes...
2017: Canadian Journal of Rural Medicine
https://www.readbyqxmd.com/read/28846153/international-survey-of-knowledge-attitudes-and-practices-of-cardiologists-regarding-prevention-and-management-of-cardiac-implantable-electronic-device-infections
#19
Daniel C DeSimone, Anwar A Chahal, Christopher V DeSimone, Samuel J Asirvatham, Paul A Friedman, Larry M Baddour, M Rizwan Sohail
BACKGROUND: Cardiovascular implantable electronic devices (CIEDs) can be life-saving. However, complications from CIED infection can be life-threatening, often requiring device removal. Despite publication of CIED infection management guidelines, there remains marked variation in clinical practice. OBJECTIVE: To better understand and quantify these differences, we conducted a multinational survey of practitioners of CIED management. METHODS: An electronic survey was sent to Heart Rhythm Society members, spanning 70 countries across six continents...
November 2017: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/28835382/utility-of-blood-culture-among-children-hospitalized-with-community-acquired-pneumonia
#20
MULTICENTER STUDY
Mark I Neuman, Matthew Hall, Susan C Lipsett, Adam L Hersh, Derek J Williams, Jeffrey S Gerber, Thomas V Brogan, Anne J Blaschke, Carlos G Grijalva, Kavita Parikh, Lilliam Ambroggio, Samir S Shah
BACKGROUND AND OBJECTIVES: National guidelines recommend blood cultures for children hospitalized with presumed bacterial community-acquired pneumonia (CAP) that is moderate or severe. We sought to determine the prevalence of bacteremia and characterize the microbiology and penicillin-susceptibility patterns of positive blood culture results among children hospitalized with CAP. METHODS: We conducted a cross-sectional study of children hospitalized with CAP in 6 children's hospitals from 2007 to 2011...
September 2017: Pediatrics
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