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Non sustained ventricular tachycardia

Sang-Geon Cho, Zeenat Jabin, Ki Seong Park, Jahae Kim, Sae-Ryung Kang, Seong Young Kwon, Geum-Cheol Jeong, Minchul Song, Jong Sang Kim, Jae Yeong Cho, Hyun Kuk Kim, Ho-Chun Song, Jung-Joon Min, Hee-Seung Bom
PURPOSE: The aim of this study was to evaluate the prognostic value of additional evaluation of left ventricular mechanical dyssynchrony (LVMD) by gated myocardial perfusion single-photon emission computed tomography (GMPS) in patients with acute myocardial infarction (MI) and multivessel disease. METHODS: One hundred and nine acute MI patients with >50 % stenosis in at least one non-culprit artery who underwent GMPS within 2 weeks were enrolled. All patients underwent successful revascularization of the culprit arteries...
October 18, 2016: European Journal of Nuclear Medicine and Molecular Imaging
Andrzej Mysiak, Małgorzata Kobusiak-Prokopowicz, Konrad Kaaz, Kamila Jarczewska, Wojciech Glabisz
BACKGROUND: The theory of chaos proves a deterministic mechanism of induction of multiple complex processes previously thought to be random in nature. This research explains how these complex processes develop. The aim of the study was to test the hypothesis of the chaotic nature of myocardial electrical events during ventricular tachycardia (VT) and ventricular fibrillation (VF). METHODS: Original hardware and software was developed for digitalization of on-line electrocardiography (ECG) data, with the functions of automatic and manual identification as well as categorization of specific ventricular arrhythmias...
October 13, 2016: Cardiology Journal
Bingbo Hou, Lihui Zheng, Guodong Niu, Lingmin Wu, Yu Qiao, Wei Sun, Ligang Ding, Gang Chen, Shu Zhang, Reginald Liew, Yan Yao
AIMS: This study was aimed to report the characteristics and treatment of ventricular tachycardia (VT) following surgical treatment of pulmonary stenosis with intact ventricular septum. METHODS AND RESULTS: Five patients underwent radiofrequency catheter ablation for sustained monomorphic left bundle branch block (LBBB) type VT who previously underwent surgical treatment of pulmonary stenosis. Except stimulation, voltage and activation mapping was performed using three-dimensional (3D) electro-anatomic mapping and ablation was applied accordingly...
October 12, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Nabeel Sheikh, Michael Papadakis, Vasileios F Panoulas, Keerthi Prakash, Lynne Millar, Paolo Adami, Abbas Zaidi, Sabiha Gati, Mathew Wilson, Gerald Carr-White, Maria Teresa Esteban Tomé, Elijah R Behr, Sanjay Sharma
BACKGROUND: This study investigated the influence of African/Afro-Caribbean (black) ethnicity on the clinical profile and outcomes in hypertrophic cardiomyopathy (HCM). METHODS: 425 consecutive patients with HCM (163 black and 262 Caucasians (white); mean age 52.5±16.6 years) were assessed at three cardiomyopathy centres. Repeat assessments were performed every 6-12 months and mean follow-up was 4.3±3.0 years. The primary outcome was a composite of cardiovascular death, cardiac arrest or appropriate device therapy...
September 27, 2016: Heart: Official Journal of the British Cardiac Society
Robert W Loar, Athar M Qureshi, Christina Y Miyake, Santiago O Valdes, Jeffrey J Kim, Caridad M De la Uz
BACKGROUND: Percutaneous pulmonary valve implantation (PPVI) is utilized for dysfunctional right ventricular outflow tracts (RVOT) to relieve obstruction, regurgitation, and RV dysfunction. PPVI has not been reported to induce arrhythmias. This study is the first to report the incidence of ventricular tachycardia (VT) after PPVI. METHODS: This was a retrospective study of all patients who had PPVI at a single institution. All patients were admitted after PPVI for overnight telemetry monitoring...
September 26, 2016: Journal of Interventional Cardiology
Walther H W Schulze, Zhong Chen, Jatin Relan, Danila Potyagaylo, Martin W Krueger, Rashed Karim, Manav Sohal, Anoop Shetty, YingLiang Ma, Nicholas Ayache, Maxime Sermesant, Herve Delingette, Julian Bostock, Reza Razavi, Kawal S Rhode, Christopher A Rinaldi, Olaf Dössel
ECG imaging is an emerging technology for the reconstruction of cardiac electric activity from non-invasively measured body surface potential maps. In this case report, we present the first evaluation of transmurally imaged activation times against endocardially reconstructed isochrones for a case of sustained monomorphic ventricular tachycardia (VT). Computer models of the thorax and whole heart were produced from MR images. A recently published approach was applied to facilitate electrode localization in the catheter laboratory, which allows for the acquisition of body surface potential maps while performing non-contact mapping for the reconstruction of local activation times...
September 20, 2016: Medical & Biological Engineering & Computing
Parikshit S Sharma, Pierre Bordachar, Kenneth A Ellenbogen
The implantable cardiac defibrillator (ICD) has been an effective tool for prevention of sudden cardiac death (SCD) in populations at high risk for life-threatening sustained ventricular tachycardia (VT) and ventricular fibrillation (VF). However, ICD implantation is dependent on defining ventricular substrate, evaluating the future risk of SCD and estimation of the patient's overall survival. The ability to predict risk of SCD is often difficult. If ventricular dysfunction (a surrogate marker for the risk of SCD) improves, ICD therapy may not be indicated...
August 25, 2016: European Heart Journal
M A Hieger, K F Maskell, M J Moss, S W Powell, K L Cumpston
Dofetilide is a class III antiarrhythmic used for treating atrial dysrhythmias. Though its adverse effects are well described in routine use, very little is known about dofetilide toxicity in overdose. This is a retrospective case series of consecutive patients reported to our poison center after dofetilide overdose. Twenty-seven cases were included. Seventeen patients were treated at a healthcare facility, and of these, eight were admitted. Twenty-one patients took one extra capsule, four took someone else's medication, one took three extra capsules, and one had a large intentional overdose...
August 26, 2016: Cardiovascular Toxicology
Chin-Yu Lin, Shih-Lin Chang, Fa-Po Chung, Yun-Yu Chen, Yenn-Jiang Lin, Li-Wei Lo, Yu-Feng Hu, Ta-Chuan Tuan, Tze-Fan Chao, Jo-Nan Liao, Yao-Ting Chang, Chung-Hsing Lin, Suresh Allamsetty, Rohit Walia, Abigail Louise D Te, Shinya Yamada, Shuo-Ju Chiang, Hsuan-Ming Tsao, Shih-Ann Chen
BACKGROUND: The impact of non-sustained ventricular tachycardia (NSVT) on the risk of thromboembolic event and clinical outcomes in patients without structural heart disease remains undetermined. This study aimed to evaluate the association between NSVT and clinical outcomes. METHODS: The study population of 5903 patients was culled from the "Registry of 24-hour ECG monitoring at Taipei Veterans General Hospital" (REMOTE database) between January 1, 2002 and December 31, 2004...
2016: PloS One
Jinzhu Hu, Shan Zeng, Qiongqiong Zhou, Wengen Zhu, Zhenyan Xu, Jianhua Yu, Kui Hong
BACKGROUND: At present, the role of ventricular tachycardia (VT) non-inducibility after ablation in patients with non-ischemic cardiomyopathy (NICM) remains controversial. We conducted a meta-analysis of the published literature to assess whether VT non-inducibility after ablation could predict reduced VT recurrence and mortality in patients with NICM. METHODS: PubMed, ScienceDirect, and the Cochrane library were searched for studies evaluating the effects of VT non-inducibility after catheter ablation on the long-term outcome in NICM patients with sustained VT...
November 1, 2016: International Journal of Cardiology
A McCombe, F Touma, D Jackson, C Canniffe, P Choudhary, L Pressley, D Tanous, Peter J Robinson, D Celermajer
BACKGROUND: Congenitally corrected transposition of the great arteries (ccTGA) is a rare congenital heart disease. There have been only few reports of sudden cardiac death (SCD) in patients with ccTGA and reasonable ventricular function. METHODS: A retrospective review of the medical records of all patients attending our adult congenital heart centre, with known ccTGA. RESULTS: From a database of over 3500 adult patients with congenital heart disease, we identified 39 (∼1%) with ccTGA and 'two-ventricle' circulations...
2016: Open Heart
Hannah G van Velzen, Pieter A Vriesendorp, Rogier A Oldenburg, Marjon A van Slegtenhorst, Jolanda van der Velden, Arend F L Schinkel, Michelle Michels
Pathogenic gene mutations are found in about 50% of patients with hypertrophic cardiomyopathy (HC). Previous studies have shown an association between sarcomere mutations and medium-term outcome. The association with long-term outcome has not been described. The aim of this cohort study was to assess the long-term outcomes of patients with genotype positive (G+) and genotype negative (G-) HC. The study population consisted of 626 patients with HC (512 probands and 114 relatives) who underwent phenotyping and genetic testing from 1985 to 2014...
September 15, 2016: American Journal of Cardiology
Dong Geum Shin, Hye-Jeong Lee, Junbeom Park, Jae-Sun Uhm, Hui-Nam Pak, Moon-Hyoung Lee, Young Jin Kim, Boyoung Joung
BACKGROUND: Left ventricular late gadolinium enhancement (LV-LGE) by cardiac magnetic resonance (CMR) imaging has been associated with adverse clinical outcomes in patients with non-ischemic cardiomyopathy (NICM). However, an association between the characteristics of the LGE and arrhythmic risk has not been demonstrated consistently. This study evaluated the impact of the LV-LGE characteristics on the arrhythmia risk in patients with NICM. METHODS: This study enrolled 365 consecutive patients (54±15years) with NICM who underwent CMR imaging...
November 1, 2016: International Journal of Cardiology
Bryant Priromprintr, Michael J Silka, Jonathan Rhodes, Anjan S Batra
BACKGROUND: Although percutaneous Melody valve implant has become an accepted alternative to surgical pulmonary valve replacement in patients with congenital heart disease (CHD), the benefit regarding frequency and severity of arrhythmias remains undefined. OBJECTIVE: This study evaluated the impact of Melody valve implant on the type and frequency of arrhythmias during cardiopulmonary exercise testing (CPET) and subsequent clinical outcome. METHODS: As part of the phase I Melody valve clinical trial, 136 patients with CHD underwent prospective serial evaluation including CPET prior to, 6 months after, and annually for 5 years...
July 21, 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Piotr Bienias, Anna Łusakowska, Michał Ciurzyński, Zuzanna Rymarczyk, Katarzyna Irzyk, Katarzyna Kurnicka, Anna Kamińska, Piotr Pruszczyk
BACKGROUND: Patients with myotonic muscular dystrophy (dystrophia myotonica, DM) are at risk of sudden cardiac death due to diverse arrhythmias, especially progressive atrioventricular (AV) conduction abnormalities. However, there are limited data on supraventricular and potentially life-threatening ventricular arrhythmias, especially according to type 1 and type 2 DM. METHODS: A group of 94 unselected consecutive patients with genetically confirmed DM and 45 healthy controls underwent electrocardiography, echocardiography, and 24-hour Holter monitoring...
September 2016: Pacing and Clinical Electrophysiology: PACE
Masayoshi Kiyokuni, Masaaki Konishi, Kentaro Sakamaki, Chika Kawashima, Masatoshi Narikawa, Hiroshi Doi, Kiwamu Iwata, Sakie Tomari, Naoki Nakayama, Naohiro Komura, Takayuki Mitsuhashi, Hideto Yano, Teruyasu Sugano, Tomoaki Ishigami, Tsutomu Endo, Toshiyuki Ishikawa, Takeharu Yamanaka, Kazuo Kimura
BACKGROUND: An early IV beta blocker during primary percutaneous coronary intervention (PCI) has been shown to reduce infarct size in ST-segment elevation acute myocardial infarction (STEMI), although the underlying mechanism is unknown. The aim of this study was to investigate the efficacy of early infusion of landiolol, the short-acting beta-1 adrenergic receptor blocker, on the reperfusion status in a STEMI. METHODS: We conducted a prospective, single-group trial of landiolol during the primary PCI for a STEMI...
October 15, 2016: International Journal of Cardiology
Saurabh Kumar, Jorge Romero, Nishaki K Mehta, Akira Fujii, Sunil Kapur, Samuel H Baldinger, Chirag R Barbhaiya, Bruce A Koplan, Roy M John, Laurence M Epstein, Gregory F Michaud, Usha B Tedrow, William G Stevenson
BACKGROUND: Long-term outcomes after ventricular tachycardia (VT) ablation are sparsely described. OBJECTIVES: The purpose of this study was to describe long-term prognosis after VT ablation in patients with no structural heart disease (no SHD), ischemic cardiomyopathy (ICM), and nonischemic cardiomyopathy (NICM). METHODS: Consecutive patients (N = 695: no SHD, 98; ICM, 358; NICM, 239) ablated for sustained VT were followed for a median of 6 years...
October 2016: Heart Rhythm: the Official Journal of the Heart Rhythm Society
Leonardo Pippa Gadioli, Carlos Henrique Miranda, Antonio Osvaldo Pintya, Alexandre Baldini de Figueiredo, André Schmidt, Benedito Carlos Maciel, José Antonio Marin-Neto, Marcus Vinicius Simões
BACKGROUND: To investigate the correlation between the extent of myocardial sympathetic denervation and fibrosis and the presence of degrees of severity of ventricular arrhythmias in chronic Chagas cardiomyopathy (CCC). METHODS: Forty-three CCC patients with left ventricular ejection fraction (LVEF) ≥ 35% were divided into three groups: SVT group-presenting Sustained Ventricular Tachycardia (SVT) (n = 15), NSVT group-exhibiting episodes of non-SVT (NSVT) on 24-h Holter monitoring (n = 11), and Control group-exhibiting neither SVT nor episodes of NSVT (n = 17)...
July 5, 2016: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
Juan Acosta, Nuno Cabanelas, Diego Penela, Juan Fernández-Armenta, David Andreu, Roger Borràs, Viatcheslav Korshunov, Mario Cabrera, Francesca Vasanelli, Elena Arbelo, Eduard Guasch, Mikel Martínez, Jose M Tolosana, Lluis Mont, Antonio Berruezo
AIMS: This study assessed the benefit of peri-implantable cardioverter-defibrillator implant ventricular tachycardia (VT)-substrate ablation in patients with structural heart disease (SHD). METHODS AND RESULTS: Patients with SHD and indication for secondary prevention ICD implant were prospectively included. Patients presenting with incessant and/or slow VT or frequent (≥2) VT episodes who underwent peri-ICD VT-substrate ablation (the scar dechannelling technique) were compared with those who received ICD alone and did not meet ablation criteria...
June 27, 2016: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
Oguz Karaca, Haci M Gunes, Mehmet Onur Omaygenc, Beytullah Cakal, Sinem Deniz Cakal, Gultekin Gunhan Demir, Filiz Kizilirmak, Tayyar Gokdeniz, Irfan Barutcu, Bilal Boztosun, Fethi Kilicaslan
BACKGROUND: Although response to cardiac resynchronization therapy (CRT) has been conventionally assessed with left ventricular volume reduction, ventricular arrhythmias (ventricular tachycardia/ventricular fibrillation [VT/VF]) are of critical importance associated with unfavorable outcomes even in the "superresponders" to therapy. We evaluated the predictors of VT/VF and the association of residual dyssynchrony during follow-up. METHODS: Ninety-five patients receiving CRT were followed-up for 9 ± 3 months...
September 2016: Pacing and Clinical Electrophysiology: PACE
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