keyword
MENU ▼
Read by QxMD icon Read
search

preoperative EPO

keyword
https://www.readbyqxmd.com/read/28582302/effect-of-erythropoietin-on-transfusion-requirements-for-craniosynostosis-surgery-in-children
#1
Hattan A Aljaaly, Salah A Aldekhayel, Julian Diaz-Abele, Mihiran Karunanayka, Mirko S Gilardino
BACKGROUND: Pediatric craniosynostosis surgery is associated with significant blood loss often requiring allogenic blood transfusion (ABT). This study explores the clinical effectiveness of preoperative erythropoietin (EPO) administration in pediatric craniosynostosis surgery in reducing transfusion requirements. METHODS: A systematic review and meta-analysis of the literature was performed for studies published in English language between 1946 and 2015. Inclusion criteria included original studies in the pediatric population (0-8 years of age) involving preoperative use of EPO in craniofacial procedures with quantitative reporting of perioperative blood transfusion...
July 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28529107/is-there-a-role-for-preoperative-iron-supplementation-in-patients-preparing-for-a-total-hip-or-total-knee-arthroplasty
#2
Stephen M Petis, Brent A Lanting, Edward M Vasarhelyi, Douglas D R Naudie, Fiona E Ralley, James L Howard
BACKGROUND: Several treatment modalities exist for the treatment of perioperative anemia. We determined the effect of oral iron supplementation on preoperative anemia, and the use of blood-conserving interventions before total hip arthroplasty (THA) and total knee arthroplasty (TKA). METHODS: A total of 3435 total joint arthroplasties (1461 THAs and 1974 TKAs) were analyzed during 2 phases of a blood conservation program. The first phase used erythropoietin alfa (EPO) or intravenous (IV) iron for patients at risk for perioperative anemia...
April 27, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/28514321/patient-blood-management-in-major-orthopedic-surgery-less-erythropoietin-and-more-iron
#3
Emmanuel Rineau, Alexandra Stoyanov, Emmanuel Samson, Laurent Hubert, Sigismond Lasocki
Erythropoietin (EPO) is proposed preoperatively to reduce blood transfusion in anemic patients (hemoglobin < 13 g/dL) scheduled for a major orthopedic surgery. New intravenous iron formulations allow infusion of higher doses, increasing EPO response. In that context, we evaluated in a before-after study (n = 62 and 65 patients for each period) a new EPO administration protocol (2 injections 4 and 3 weeks before surgery, and a third if hemoglobin <13 g/dL instead of <15 g/dL 2 weeks before surgery)...
May 12, 2017: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/28150286/endogenic-erythropoietin-secretion-in-patients-undergoing-off-pump-coronary-artery-bypass-grafting
#4
Anna Drohomirecka, Mariusz Kuśmierczyk, Szymon Kocańda, Krzysztof Kuśmierski, Piotr Kołsut, Krzysztof Kotliński, Aleksandra Brutkiewicz, Grzegorz Religa, Jacek Różański, Tomasz Zieliński
BACKGROUND: Erythropoietin (EPO) deficiency or inadequate EPO secretion in response to bleeding may result in profound or prolonged anaemia after cardiac surgery. AIM: The aim of the study was to evaluate the changes in EPO secretion in patients undergoing off-pump coronary artery bypass grafting (OPCAB). METHODS: Blood samples from 43 patients (mean age 65.1 ± 7.6 years) were obtained before surgery and on the 1st, 2nd, and 6th day post isolated OPCAB...
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28039503/does-postoperative-erythropoietin-reduce-transfusions-and-hemodynamic-instability-following-liposuction-either-alone-or-associated-with-abdominoplasty-or-mammaplasty-a-comparative-prospective-study-of-50-consecutive-patients
#5
Rodrigo G Rosique, Marina J F Rosique, Mariana Quintino Rabelo
INTRODUCTION: Erythropoietin (EPO) is a hematopoietic growth factor and an alternative to avoid blood transfusion in high-blood-loss surgeries. We evaluate EPO efficacy to reduce clinically relevant anemia and dehydration in patients undergoing liposuction. METHODS: We prospectively evaluated 50 consecutive patients subjected to liposuction greater than 2.5 L and alternately assigned into two comparable groups (25 patients each), except for the postoperative administration of erythropoietin (4000 UI per day subcutaneously) during five consecutive days...
December 30, 2016: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/27826909/updates-on-preoperative-planning-limb-deformity-analysis-and-surgical-correction-for-the-growing-children-epos-meeting-marseille-2015-proceedings
#6
Eitan Segev
Successful deformity correction depends on establishing the aetiology of the deformity. Clinical examination, additional laboratory tests and consultation with other experts may be needed to complete the workup. Imaging studies should include full-length standing X-rays in all relevant planes, and additional imaging modalities like computed tomography (CT) and magnetic resonance imaging (MRI) may add information on bone morphology and growth plates' anatomy. Based on the data, analysis of the deformity and length differences is performed, followed by prediction of deformities at skeletal maturity...
December 2016: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/27659163/balloon-dilation-of-sinus-ostia-in-the-department-of-defense-diagnoses-actual-indications-and-outcomes
#7
Adrienne M Laury, Sarah N Bowe, Joshua Stramiello, Kevin C McMains
OBJECTIVES/HYPOTHESIS: To determine the primary diagnoses for which balloon catheter dilation (BCD) of sinus ostia is being employed in a profit-blind health care system, the Department of Defense. STUDY DESIGN: Retrospective chart review. METHODS: From January 1, 2011 to December 31, 2013, 319 consecutive patient charts were reviewed for International Classification of Diseases, Ninth Edition (ICD-9) diagnoses, presence of chronic rhinosinusitis (CRS) defined by the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS), preoperative Lund-Mackay scores, nasal endoscopy findings, sinuses dilated, postoperative outcomes, and complications...
March 2017: Laryngoscope
https://www.readbyqxmd.com/read/27523464/characterising-the-role-of-perioperative-erythropoietin-for-preventing-acute-kidney-injury-after-cardiac-surgery-systematic-review-and-meta-analysis
#8
REVIEW
Jahan Che Penny-Dimri, Andrew D Cochrane, Luke A Perry, Julian A Smith
BACKGROUND: The role of perioperative erythropoietin (EPO) for preventing cardiac surgery associated acute kidney injury (CSA-AKI) remains uncertain with published trials producing conflicting results. Perspective into the factors at work is needed, due to ongoing uncertainty. METHODS: We undertook the systematic review and meta-analysis of randomised-controlled trials (RCTs) using random-effects modelling. The primary outcome was safety and efficacy of perioperative EPO to prevent CSA-AKI and the secondary outcomes were change in serum creatinine, urinary neutrophil gelatinase-associated lipocalin, time in ICU, rates of postoperative transfusions, haemodialysis, and mortality...
November 2016: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/27399121/the-effectiveness-and-safety-of-preoperative-use-of-erythropoietin-in-patients-scheduled-for-total-hip-or-knee-arthroplasty-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#9
REVIEW
Yan Zhao, Chao Jiang, Huiming Peng, Bin Feng, Yulong Li, Xisheng Weng
INTRODUCTION: Because allogeneic blood transfusion carries a risk of serious complications, erythropoietin (EPO) has been used in patients scheduled for total hip or knee arthroplasty in an effort to reduce the need for allogeneic blood transfusion; however, its efficacy, cost-effectiveness, and safety are still controversial. The purpose of this review was to determine the hematopoiesis-promoting effect and potential complications, as well as the cost-effectiveness, of preoperative use of EPO in patients scheduled for total hip or knee arthroplasty...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27195774/ferric-carboxymaltose-with-or-without-erythropoietin-in-anemic-patients-with-hip-fracture-a-randomized-clinical-trial
#10
RANDOMIZED CONTROLLED TRIAL
Máximo Bernabeu-Wittel, Manuel Romero, Manuel Ollero-Baturone, Reyes Aparicio, José Murcia-Zaragoza, Manuel Rincón-Gómez, Rafael Monte-Secades, María Melero-Bascones, Clara M Rosso, Alberto Ruiz-Cantero
BACKGROUND: The increasing incidence of osteoporotic hip fracture (HF) has raised the requirements of red blood cell (RBC) transfusions, whereas this scarce resource may cause morbidity and mortality. STUDY DESIGN AND METHODS: This study was a multicenter, randomized, double-blind, clinical trial that aimed to assess efficacy of ferric carboxymaltose (FCM) with or without erythropoietin (EPO) in reducing RBC transfusion in the perioperative period of HF. Participants (patients > 65 years admitted with HF and hemoglobin [Hb] levels of 90-120 g/L) were randomly assigned to receive a preoperative single dose of 1 g of FCM (short intravenous [IV] infusion over 15 min), plus 40,000 IU of subcutaneous EPO (EPOFE arm); versus 1 g of IV FCM plus subcutaneous placebo (FE arm); and versus IV and subcutaneous placebo (placebo arm)...
September 2016: Transfusion
https://www.readbyqxmd.com/read/27102553/combination-of-erythropoietin-and-tranexamic-acid-in-bilateral-simultaneous-total-hip-arthroplasty-a-randomised-controlled-trial
#11
RANDOMIZED CONTROLLED TRIAL
Yuan-Gang Wu, Yi Zeng, Bin Shen, Hai-Bo Si, Fei Cao, Ti-Min Yang, Fu-Xing Pei
INTRODUCTION: This study aimed to evaluate whether the combination of erythropoietin (EPO) and tranexamic acid (TXA) exerted any additional benefits on the number of blood transfusions required and haematological parameters compared with TXA alone following primary bilateral simultaneous total hip arthroplasty. MATERIALS AND METHODS: We conducted a single-centre, prospective, randomised, and controlled trial at our hospital. Group EPO + TXA (n = 30) received daily subcutaneous injections EPO (10,000 IU) on preoperative days 1-4 and postoperative days 1-3...
July 25, 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
https://www.readbyqxmd.com/read/27080636/predictive-factors-for-homologous-transfusion-during-paediatric-scoliosis-surgery
#12
Claire Dupuis, Daphné Michelet, Julie Hilly, Thierno Diallo, Christophe Vidal, Honorine Delivet, Yves Nivoche, Keyvan Mazda, Souhayl Dahmani
INTRODUCTION: Blood saving strategies during paediatric spinal surgery often include recombinant erythropoietin (rEPO) and antifibrinolytic therapy (AFT). The goal of this study was to investigate additional preventive factors involved in the risk of blood transfusion. METHODS: This prospective study was designed with the aim of identifying factors associated with the perioperative (defined as the intraoperative and the first postoperative day) probability of homologous red cell transfusion during scoliosis surgery in children operated during a one year period in our institution...
December 2015: Anaesthesia, Critical Care & Pain Medicine
https://www.readbyqxmd.com/read/26907911/hepcidin-as-a-biomarker-of-impaired-renal-function-in-rat-models-for-chronic-allograft-nephropathy
#13
Dong Xue, Cuixing Zhou, Yunbo Shi, Hao Lu, Xiaozhou He
BACKGROUND To explore the use of hepcidin as a marker of impaired renal function in a rat model for chronic allograft nephropathy (CAN). MATERIAL AND METHODS Twenty-four models were developed and 20 models were included in this study, using Fisher (F344) rats (donors) and Lewis rats (recipients). Renal function tests were performed preoperatively and postoperatively. Hepcidin, interleukin-6 (IL-6), and erythropoietin levels in serum and urine were measured by enzyme-linked immunosorbent assay (ELISA). To observe pathological changes in the kidneys, 10 rats each were sacrificed at 2 months and 4 months after surgery...
February 23, 2016: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/26748489/implementing-a-blood-management-protocol-during-the-entire-perioperative-period-allows-a-reduction-in-transfusion-rate-in-major-orthopedic-surgery-a-before-after-study
#14
Emmanuel Rineau, Aurélie Chaudet, Claire Chassier, Pascal Bizot, Sigismond Lasocki
BACKGROUND: Patient blood management (PBM) must be promoted in orthopedic surgery and relies on different strategies implemented during the entire perioperative period. Our aim was to assess whether the introduction of a pre-, intra-, and postoperative PBM protocol combining erythropoietin (EPO), ferric carboxymaltose (FCM), and tranexamic acid was effective in reducing perioperative transfusion and postoperative anemia. STUDY DESIGN AND METHODS: In a two-phase prospective observational study, all patients admitted for total hip or knee arthroplasty were included the day before surgery...
March 2016: Transfusion
https://www.readbyqxmd.com/read/26601635/cost-analysis-of-tranexamic-acid-in-anemic-total-joint-arthroplasty-patients
#15
Duy L Phan, Fiyinfoluwa Ani, Ran Schwarzkopf
BACKGROUND: Preoperative anemia is present in 20% of total joint arthroplasty patients. Current preoperative treatment options, including iron supplementation (FE) and erythropoietin (EPO), are expensive. Tranexamic acid (TXA) has been adopted as an intraoperative adjunct to decrease blood loss. Our hypothesis is that TXA is a cost-effective treatment compared to FE and EPO in anemic patients. METHODS: In this study, a cost analysis was performed, comparing the material costs of TXA and packed red blood cells (PRBCs) to the theoretical administration and material costs of FE and EPO per standard preoperative anemia protocol...
March 2016: Journal of Arthroplasty
https://www.readbyqxmd.com/read/26502101/efficacy-of-erythropoietin-beta-injections-during-autologous-blood-donation-before-spinal-deformity-surgery-in-children-and-teenagers
#16
Shota Ikegami, Jun Takahashi, Shugo Kuraishi, Masayuki Shimizu, Toshimasa Futatsugi, Masashi Uehara, Kayo Horiuchi, Shigetaka Shimodaira, Hiroyuki Kato
STUDY DESIGN: Retrospective observational study OBJECTIVE.: To clarify the efficacy of recombinant human erythropoietin-beta (EPO-beta) injections during autologous blood donation (ABD) before spinal deformity surgery in children and teenagers. SUMMARY OF BACKGROUND DATA: ABD is preferred for spinal deformity surgery. A few studies have assessed the usefulness of preoperative ABD with EPO-beta in anemic patients. METHODS: Fifty-six spinal deformity surgery patients (41 females, 15 males; median age: 15 yrs; range, 5-19 yrs) underwent preoperative ABD...
November 2015: Spine
https://www.readbyqxmd.com/read/26466485/-perioperative-blood-management-strategies-for-joint-arthroplasty
#17
REVIEW
Lintao Li, Haishan Wu, Yuli Wu, Peiliang Fu, Zheru Ding
OBJECTIVE: To summarize the perioperative blood management strategies for joint arthroplasty. METHODS: The literature concerning preoperative, intraoperative, and postoperative blood management was reviewed and summarized. RESULTS: At present, a variety of blood management and conservation strategies are available. Preoperative strategies include iron supplementation, erythropoietin (EPO), and preoperative autologous donation (PAD). Intraoperative options include acute normovolemic hemodilution (ANH), antifibrinolytics, and the use of a tourniquet...
June 2015: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/26309665/impacts-of-parathyroidectomy-on-renal-anemia-and-nutritional-status-of-hemodialysis-patients-with-secondary-hyperparathyroidism
#18
Chen Chen, Hua Wu, Lin Zhong, Xin Wang, Zhuang-Jie Xing, Bi-Hu Gao
The aim of this study was to investigate the impacts of parathyroidectomy (PTX) towards the renal anemia and nutritional status of hemodialysis patients with secondary hyperparathyroidism (SHPT). 32 patients, enrolled into the blood purification center of our hospital for the hemodialysis treatment, were collected and divided into the PTX group and the non-PTX group, with 16 patients in each group. The changes of relevant indicators such as immunoreactive parathyroid hormone (iPTH), anemia and nutrition were observed before, 1-, 3-, 6-month after the treatment...
2015: International Journal of Clinical and Experimental Medicine
https://www.readbyqxmd.com/read/26087901/videoendoscopic-evaluation-of-swallowing-after-thyroidectomy-7-and-60-days
#19
Lica Arakawa-Sugueno, Alberto Rosseti Ferraz, Janaína Morandi, Dirce Maria Capobianco, Claudio Roberto Cernea, Maury Antônio Sampaio, Marco Aurélio Vamondes Kulcsar, César Augusto Simões, Lenine Garcia Brandão
Deglutition complaints are frequent after thyroidectomy. The purpose of this study was to follow-up on patients with thyroidectomy indication to compare the videoendoscopic evaluation of swallowing on the seventh day (early postoperative, EPO) and on the 60th day after thyroidectomy, (late postoperative, LPO) and to compare patients that evolved with normal laryngeal mobility (NLM) and abnormal laryngeal mobility (ALM). Nasofibroscopic evaluation was performed preoperatively (PRE), on the EPO and LPO. Two groups were compared: ALM and NLM...
October 2015: Dysphagia
https://www.readbyqxmd.com/read/26065644/efficacy-and-safety-of-erythropoietin-to-prevent-acute-kidney-injury-in-patients-with-critical-illness-or-perioperative-care-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#20
REVIEW
Chen Zhao, Zhenchuan Lin, Qimei Luo, Xi Xia, Xueqing Yu, Fengxian Huang
OBJECTIVE: The aim was to investigate the efficacy and safety of erythropoietin (EPO) to prevent acute kidney injury (AKI) in patients with critical illness or perioperative care. METHODS: Randomized controlled trials comparing EPO with placebo for AKI prevention in adult patients with critical illness or perioperative care were searched in MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Web of Science, and Clinical Trials.gov until October 2014...
June 2015: Journal of Cardiovascular Pharmacology
keyword
keyword
109433
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"