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https://www.readbyqxmd.com/read/29951140/nonsustained-ventricular-tachycardia-does-not-affect-the-prognosis-of-neuromuscular-diseases-a-preliminary-and-retrospective-study
#1
Takahiro Kamihara, Fumihiko Yasuma, Toyoaki Murohara
Background: Nonsustained ventricular tachycardia (NSVT) is sometimes observed in patients with neuromuscular diseases (NMDs). The aim of this study was to assess the role of NSVT in the survival prognosis of NMD patients. Methods: We retrospectively analyzed the patients with NMDs who had undergone Holter ECG recordings at a single center between February and August 2012. Sixty-eight patients were enrolled in this study. The 5 year follow-up was assessed according to the cumulative event-free rate...
June 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29897106/clinical-parameters-to-optimize-patient-selection-for-subcutaneous-and-transvenous-implantable-defibrillator-therapy
#2
Anne-Floor B E Quast, Tom F Brouwer, Fleur V Y Tjong, Arthur A M Wilde, Reinoud E Knops
BACKGROUND: The subcutaneous implantable cardioverter-defibrillator (S-ICD) lacks the antitachycardia pacing (ATP) capability of tranvenous ICDs (TV-ICD). S-ICD patient selection can be challenging as some patients may benefit from ATP. We aim to identify clinical predictors of ATP benefit, in order to improve patient selection for S-ICD or TV-ICD therapy. METHODS: De novo single- and dual-chamber TV-ICD patients implanted between March 2011 and December 2015 were included...
June 13, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29887423/the-effect-of-intracoronary-sodium-nitrite-on-the-burden-of-ventricular-arrhythmias-following-primary-percutaneous-coronary-intervention-for-acute-myocardial-infarction
#3
Daniel A Jones, Krishnaraj S Rathod, Anna Williamson, Deirdre Harrington, Mervyn Andiapen, Sven van Eijl, Mark Westwood, Sotiris Antoniou, Richard J Schilling, Amrita Ahluwalia, Anthony Mathur
OBJECTIVE: Pre-clinical evidence suggests delivery of nitric oxide (NO) through administration of inorganic nitrite suppresses arrhythmias resulting from acute ischaemia and reperfusion (I/R). To date no assessment of whether inorganic nitrite might limit reperfusion arrhythmia has occurred in man, therefore we explored the effects on I/R-induced ventricular arrhythmias in the NITRITE-AMI cohort. METHODS: In the NITRITE-AMI cohort, Holter analysis was performed prior to and for 24 h after primary PCI in 80 patients who received either intra-coronary sodium nitrite (N = 40) or placebo (N = 40) during primary PCI for AMI...
September 1, 2018: International Journal of Cardiology
https://www.readbyqxmd.com/read/29678624/autonomic-cardiovascular-control-and-cardiac-arrhythmia-in-two-pregnant-women-with-hypertrophic-cardiomyopathy-insights-from-icd-monitoring
#4
Pietro Francia, Carmen Adduci, Beatrice Musumeci, Lorenzo Semprini, Francesca Palano, Luigi Zezza, Massimo Volpe, Camillo Autore
In women with hypertrophic cardiomyopathy (HCM), pregnancy prompts major changes in hemodynamic and cardiac autonomic function that may precipitate heart failure (HF) or increase the risk of cardiac arrhythmia. We report the clinical follow-up of two patients with non-obstructive HCM implanted with a cardioverter defibrillator (ICD) allowing for continuous analysis of heart rate (HR), heart rate variability (HRV) and cardiac arrhythmia throughout the entire course of pregnancy. Both patients experienced increased HR and decreased HRV from the early stages of pregnancy, which persisted until delivery...
April 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29657589/prognostic-significance-of-nonsustained-ventricular-tachycardia-in-patients-receiving-cardiac-resynchronization-therapy-for-primary-prevention-analysis-of-the-japan-cardiac-device-treatment-registry-database
#5
Hisashi Yokoshiki, Akihiko Shimizu, Takeshi Mitsuhashi, Hiroshi Furushima, Yukio Sekiguchi, Tetsuyuki Manaka, Nobuhiro Nishii, Takeshi Ueyama, Norishige Morita, Hideo Okamura, Takashi Nitta, Kenzo Hirao, Ken Okumura
Background: Whether nonsustained ventricular tachycardia (NSVT) is a marker of increased risk of sustained ventricular tachyarrhythmias (VTAs) remains to be established in patients receiving cardiac resynchronization therapy with a defibrillator (CRT-D) for primary prevention. Methods: Among the follow-up data of the Japan cardiac device treatment registry (JCDTR) with an implantation date between January 2011 and August 2015, information regarding a history of NSVT before the CRT-D implantation for primary prevention had been registered in 269 patients...
April 2018: Journal of Arrhythmia
https://www.readbyqxmd.com/read/29237655/evaluation-using-cardiac-insertable-devices-and-telephone-in-hypertrophic-cardiomyopathy-elucidate-hcm-rationale-and-design-a-prospective-observational-study-on-incidence-of-arrhythmias-in-sweden
#6
Peter Magnusson, Stellan Mörner
INTRODUCTION: Hypertrophic cardiomyopathy (HCM) is a heterogeneous disease associated with sudden cardiac death (SCD) mainly due to ventricular tachycardia (VT) or fibrillation even though life-threatening bradycardia occurs. Risk stratification takes several variables into consideration including non-sustained VT (NSVT). An implantable cardioverter defibrillator effectively prevents SCD.Atrial fibrillation (AF) is common among patients with HCM and warrants anticoagulation even without conventional risk factors according to European guidelines...
December 12, 2017: BMJ Open
https://www.readbyqxmd.com/read/29224709/prevalence-and-prognostic-significance-of-nonsustained-ventricular-tachycardia-in-patients-with-a-left-ventricular-ejection-fraction-from-35-to-50
#7
Sorcha M Allen, Victor A Abrich, Paul S Bibby, Daniel Fishman, Win-Kuang Shen, Dan Sorajja
The risk of life-threatening ventricular arrhythmias in patients with mild-to-moderately reduced left ventricular ejection fraction (LVEF) is unknown. This retrospective case-control study aims to identify the prevalence, risk factors, and outcomes associated with the development of nonsustained ventricular tachycardia (NSVT) as documented on permanent pacemakers or implantable loop recorders in tertiary care center patients with an LVEF of 35% to 50%. Data pertaining to patient demographics, previous medical history, heart failure functional class, echocardiographic parameters, and survival were compared between the groups...
February 1, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29146274/effects-of-angiotensin-neprilysin-inhibition-compared-to-angiotensin-inhibition-on-ventricular-arrhythmias-in-reduced-ejection-fraction-patients-under-continuous-remote-monitoring-of-implantable-defibrillator-devices
#8
Carlos de Diego, Luis González-Torres, José María Núñez, Raúl Centurión Inda, David A Martin-Langerwerf, Antonio D Sangio, Piotr Chochowski, Pilar Casasnovas, Julio C Blazquéz, Jesús Almendral
BACKGROUND: Angiotensin-neprilysin inhibition compared to angiotensin inhibition decreased sudden cardiac death in patients with reduced ejection fraction heart failure (rEFHF). The precise mechanism remains unclear. OBJECTIVE: The purpose of this study was to explore the effect of angiotensin-neprilysin inhibition on ventricular arrhythmias compared to angiotensin inhibition in rEFHF patients with an implantable cardioverter-defibrillator (ICD) and remote monitoring...
March 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29069369/high-resolution-three-dimensional-late-gadolinium-enhanced-cardiac-magnetic-resonance-imaging-to-identify-the-underlying-substrate-of-ventricular-arrhythmia
#9
Alexia Hennig, Marjorie Salel, Frederic Sacher, Claudia Camaioni, Soumaya Sridi, Arnaud Denis, Michel Montaudon, François Laurent, Pierre Jais, Hubert Cochet
Aims: Cardiac magnetic resonance (CMR) is recommended as a second-line method to diagnose ventricular arrhythmia (VA) substrate. We assessed the diagnostic yield of CMR including high-resolution late gadolinium-enhanced (LGE) imaging. Methods and results: Consecutive patients with sustained ventricular tachycardia (VT), non-sustained VT (NSVT), or ventricular fibrillation/aborted sudden death (VF/SCD) underwent a non-CMR diagnostic workup according to current guidelines, and CMR including LGE imaging with both a conventional breath-held and a free-breathing method enabling higher spatial resolution (HR-LGE)...
October 23, 2017: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29064790/-the-prognostic-value-of-kcnq1-gene-mutations-in-patients-after-myocardial-infarction
#10
Marlena Olszak-Waśkiewicz, Elżbieta Kramarz
INTRODUCTION: Ion channel gene mutations are risk factors for SCD. THE AIM: To assess the prognostic value of A2753831C, C2505734T, C2505846A, G2753881A, T2755854C and T2755875G mutations in the KCNQ1 gene in patients after MI. MATERIAL AND METHODS: The study group of 100 patients after MI was divided into two groups: patients with mutations (n=23) and patients without mutations (n=77). The subjects underwent physical examinations, laboratory tests, ECG, Holter ECG and echocardiography...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29064614/accuracy-of-the-pacemaker-event-recorder-versus-holter-ecg-to-detect-both-symptomatic-and-asymptomatic-ventricular-arrhythmias
#11
Stela Maria Vitorino Sampaio, Neyle Moara Craveiro, Francisco Darrieux, Ítalo Martins de Oliveira, Mauricio Scanavacca, Denise Hachul
BACKGROUND: Although new pacemakers can register cardiac rhythm, few studies were performed evaluating their accuracy in diagnosing ventricular arrhythmias (VA). This study aimed to assess the correlation and agreement between the pacemaker's monitor and the ambulatory Holter in detecting VA. METHODS AND RESULTS: We studied 129 patients with pacemakers, mean age 68.6 ± 19.1 years, 54.8% female. Once Holter monitoring was connected, the pacemakers' event counters were reset and clocks of both systems were synchronized to register electrocardiograms (ECG) simultaneously...
January 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29038823/left-ventricular-twist-in-hypertrophic-cardiomyopathy-predictor-of-nonsustained-ventricular-tachycardia
#12
O Candan, C Gecmen, A Kalaycı, E Bayam, A Guner, S Gunduz, S Cersit, M Ozkan
BACKGROUND: We investigated the efficacy of clinical and classic echocardiographic parameters in predicting the occurrence of nonsustained ventricular tachycardia (NsVT) in patients with hypertrophic cardiomyopathy (HCM). METHODS: The study comprised 59 patients with HCM (47 male, [80%]; mean age, 48.48 ± 14.16 years). Clinical, electrocardiographic, as well as classic two-dimensional and speckle-tracking echocardiography (STE) data were collected. All patients had Holter monitoring within 24-72 h of the echocardiographic examination...
October 16, 2017: Herz
https://www.readbyqxmd.com/read/28977051/non-sustained-ventricular-tachycardia-episodes-predict-future-hospitalization-in-icd-recipients-with-heart-failure
#13
Fatih Mehmet Uçar, Mustafa Adem Yilmaztepe, Gökay Taylan, Meryem Aktoz
BACKGROUND: Implantable cardioverter-defibrillator (ICD) therapy is well known to reduce mortality in selected patients with heart failure (HF). OBJECTIVE: To investigate whether monitored episodes of non-sustained ventricular tachycardia (NSVT) might predict future HF hospitalizations in ICD recipients with HF. METHODS: We examined 104 ICD recipients (mean age: 60 ± 10.1 years, 80.8 % male) with HF who were referred to our outpatient clinic for device follow-up...
October 2017: Arquivos Brasileiros de Cardiologia
https://www.readbyqxmd.com/read/28965256/effects-of-rosuvastatin-and-atorvastatin-on-nonsustained-ventricular-tachycardia-in-patients-with-st-elevation-myocardial-infarction-a-retrospective-analysis
#14
Xianqing Hu, Jian Cheng, Chunjian Li
BACKGROUND/AIMS: Early and intensive atorvastatin treatment can decrease nonsustained ventricular tachycardia (nsVT) in patients with ST-segment elevation myocardial infarction (STEMI). The objective of this study was to compare the effects of hydrophilic rosuvastatin and lipophilic atorvastatin on nsVT in STEMI patients treated with primary percutaneous coronary intervention (PCI). METHODS: The data from a cohort of patients undergoing primary PCI at Jinhua Municipal Central Hospital from January 1, 2013 through June 30, 2016 were analyzed...
January 2018: European Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/28931939/survival-and-prognostic-factors-in-hypertrophic-cardiomyopathy-a-meta-analysis
#15
Qun Liu, Diandian Li, Alan E Berger, Roger A Johns, Li Gao
Hypertrophic cardiomyopathy (HCM) is a clinically and genetically heterogeneous disorder but data on survival rates are still conflicting and have not so far been quantitatively reviewed. The aim of this study is to conduct a meta-analysis of cohort studies to assess pooled survival rates and prognostic factors for survival in patients with HCM. Nineteen studies were included representing 12,146 HCM patients. The pooled 1-, 3-, 5- and 10-year survival rates were 98.0%, 94.3%, 82.2% and 75.0%, respectively. Among patients with HCM, age, NYHA functional class, family history of sudden death (FHSD), syncope, atrial fibrillation, non-sustained ventricular tachycardia (nsVT), maximum left ventricular wall thickness and obstruction were significant prognostic factors for cardiovascular death...
September 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28921787/myocardial-bridging-is-associated-with-exercise-induced-ventricular-arrhythmia-and-increases-in-qt-dispersion
#16
Makiko Nishikii-Tachibana, Vedant S Pargaonkar, Ingela Schnittger, Francois Haddad, Ian S Rogers, Jennifer A Tremmel, Paul J Wang
BACKGROUND: A myocardial bridge (MB) has been associated with ventricular arrhythmia and sudden death during exercise. QT dispersion (QTd) is a measure of abnormal repolarization and may predict ventricular arrhythmia. We investigated the frequency of ventricular arrhythmias during exercise and the QTd at rest and after exercise, in patients with an MB compared to a normal cohort. METHODS: We studied the rest and stress ECG tracings of patients with an MB suspected by focal septal buckling on exercise echocardiography (EE) (Echo-MB group, N = 510), those with an MB confirmed by another examination (MB group, N = 110), and healthy controls (Control group, N = 198)...
March 2018: Annals of Noninvasive Electrocardiology
https://www.readbyqxmd.com/read/28705070/comparison-of-two-european-models-estimating-risk-of-sudden-cardiac-death-in-hypertrophic-cardiomyopathy
#17
Pawel Rubis, Barbara Biernacka-Fijalkowska, Lusine Khachatryan, Aleksandra Karabinowska, Patrycja Faltyn, Ewa Dzwiecka, Sylwia Wisniowska-Smialek, Lidia Tomkiewcz-Pająk, Piotr Podolec
Objective Hypertrophic cardiomyopathy (HCM) is associated with a risk of sudden cardiac death (SCD). Several models have been developed to estimate SCD risk and guide preventive therapy. The comparison of the previous 2003 with novel 2014 SCD risk models have never been studied. Methods Over a year we included 103 consecutive HCM patients without previous cardiac arrest and/or ICD implanted (65% males; aged 53.3 ± 13.9 years; mean EF 62.3 ± 18%). The SCD risk was calculated for each patient. Results Based on the 2003 model, patients had following scores: 0 points -15 (15%) patients, 1-28 (27%), 2-34 (33%), 3-18 (17%), ≥ 4-8 (8%)...
July 14, 2017: Acta Cardiologica
https://www.readbyqxmd.com/read/28633348/lifelong-arrhythmic-risk-stratification-in-arrhythmogenic-right-ventricular-cardiomyopathy-distribution-of-events-and-impact-of-periodical-reassessment
#18
Chiara Cappelletto, Davide Stolfo, Antonio De Luca, Bruno Pinamonti, Giulia Barbati, Alberto Pivetta, Marco Gobbo, Francesca Brun, Marco Merlo, Gianfranco Sinagra
Aims: The arrhythmic risk stratification of arrhythmogenic right ventricular cardiomyopathy (ARVC) remains controversial. We evaluated the long-term distribution of life-threatening arrhythmic events assessing the impact of periodical risk reassessment. Methods and results: Ninety-eight ARVC patients with no previous major ventricular arrhythmias were retrospectively analysed. Patients were assessed at baseline, at 22 [inter-quartile range (IQR) 16-26], 49 (IQR 41-55) and 97 months (IQR 90-108)...
June 1, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/28612913/the-usefulness-of-sst2-and-galectin-3-as-novel-biomarkers-for-better-risk-stratification-in-hypertrophic-cardiomyopathy
#19
Monika Gawor, Mateusz Śpiewak, Jadwiga Janas, Katarzyna Kożuch, Aleksandra Wróbel, Łukasz Mazurkiewicz, Rafał Baranowski, Magdalena Marczak, Jacek Grzybowski
BACKGROUND: Estimation of sudden cardiac death (SCD) risk is an integral part of clinical management of patients with hypertrophic cardiomyopathy (HCM). Identification of novel biomarkers of this disease can provide additional criteria for SCD risk stratification. Soluble suppression of tumourigenicity (sST2) and galectin-3 (Gal-3) are useful biomarkers for prognosis of heart failure (HF). Both of them appear to mediate cardiac fibrosis - an important pathogenetic process in HCM. Data about sST2 and Gal-3 usefulness in patients with HCM are limited...
2017: Kardiologia Polska
https://www.readbyqxmd.com/read/28541596/effects-of-ivabradine-and-beta-blocker-therapy-on-dobutamine-induced-ventricular-arrhythmias
#20
COMPARATIVE STUDY
Kadir Uğur Mert, Gurbet Özge Mert, Bektas Morrad, Senan Tahmazov, Fezan Mutlu, Yüksel Çavuşoglu
BACKGROUND: Indirect evidences suggest that the If blocker ivabradine may exert an antiarrhythmic effect in ventricular myocardium in heart failure (HF) patients by inhibiting spontaneous depolarisations, but the clinical relevance of this mechanism is not known. Dobutamine (DOB) has been known to increase heart rate and the incidence of cardiac arrhythmias. AIM: In this study, we evaluated the effects of ivabradine on DOB-induced ventricular arrhythmias and compared them with those of beta-blocker (BB) therapy...
2017: Kardiologia Polska
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