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Transient Global Amnesia

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https://www.readbyqxmd.com/read/29123402/transient-global-amnesia-current-perspectives
#1
REVIEW
David R Spiegel, Justin Smith, Ryan R Wade, Nithya Cherukuru, Aneel Ursani, Yuliya Dobruskina, Taylor Crist, Robert F Busch, Rahim M Dhanani, Nicholas Dreyer
Transient global amnesia (TGA) is a clinical syndrome characterized by the sudden onset of an extraordinarily large reduction of anterograde and a somewhat milder reduction of retrograde episodic long-term memory. Additionally, executive functions are described as diminished. Although it is suggested that various factors, such as migraine, focal ischemia, venous flow abnormalities, and epileptic phenomena, are involved in the pathophysiology and differential diagnosis of TGA, the factors triggering the emergence of these lesions are still elusive...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/29038979/decreased-metabolism-in-the-posterior-medial-network-with-concomitantly-increased-metabolism-in-the-anterior-temporal-network-during-transient-global-amnesia
#2
SangHak Yi, Young Ho Park, Jae-Won Jang, Jae-Sung Lim, In Kook Chun, SangYun Kim
Perturbation of corticohippocampal circuits is a key step in the pathogenesis of transient global amnesia. We evaluated the spatial distribution of altered cerebral metabolism to determine the location of the corticohippocampal circuits perturbed during the acute stage of transient global amnesia. A consecutive series of 12 patients with transient global amnesia who underwent (18)F-fluorodeoxyglucose positron emission tomography within 3 days after symptom onset was identified. We used statistical parametric mapping with two contrasts to identify regions of decreased and increased brain metabolism in transient global amnesia patients compared with 25 age-matched controls...
October 16, 2017: Brain Topography
https://www.readbyqxmd.com/read/29030365/transient-global-amnesia-following-a-whole-body-cryotherapy-session
#3
Justin Carrard, Anne Chantal Lambert, Daniel Genné
Whole-body cryotherapy (WBC), which consists of a short exposure to very cold and dry air in special 'cryo-chambers', is believed to reduce inflammation and musculoskeletal pain as well as improve athletes' recovery. This is the case of a 63-year-old male, who presented with transient global amnesia (TGA) after undertaking a WBC session. TGA is a clinical syndrome characterised by a sudden onset of anterograde amnesia, sometimes coupled with a retrograde component, lasting up to 24 hours without other neurological deficits...
October 13, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29024985/transient-global-amnesia-clinical-and-imaging-features
#4
Richard G Kavanagh, Amy O'Brien, Niall Tubridy, Graeme McNeill, Ronan P Killeen
No abstract text is available yet for this article.
August 28, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/28936081/transient-global-amnesia
#5
V Sivakumar, Venkatraman Indiran
No abstract text is available yet for this article.
August 2017: Journal of Neurosciences in Rural Practice
https://www.readbyqxmd.com/read/28919157/ethyl-acetate-fraction-of-trichilia-catigua-restores-long-term-retrograde-memory-and-reduces-oxidative-stress-and-inflammation-after-global-cerebral-ischemia-in-rats
#6
Jacqueline Godinho, Rúbia Maria Weffort de Oliveira, Anacharis Babeto de Sa-Nakanishi, Cristiano Correia Bacarin, Claudia Hitomi Huzita, Renata Longhini, João Carlos P Mello, Celso Vataru Nakamura, Isolde Santos Previdelli, Matheus Henrique Dal Molin Ribeiro, Humberto Milani
We originally reported that an ethyl-acetate fraction (EAF) of Trichilia catigua prevented the impairment of water maze learning and hippocampal neurodegeneration after transient global cerebral (TGCI) in mice. We extended that previous study by evaluating whether T. catigua (i) prevents the loss of long-term retrograde memory assessed in the aversive radial maze (AvRM), (ii) confers hippocampal and cortical neuroprotection, and (iii) mitigates oxidative stress and neuroinflammation in rats that are subjected to the four vessel occlusion (4-VO) model of TGCI...
January 30, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/28884957/long-term-sequelae-of-hippocampal-lesions-in-patients-with-transient-global-amnesia-a-multiparametric-mri-study
#7
Xiaochuan Wang, Ran Zhang, Wenping Wei, Haibo Jiang, Zhongming Gao, Jianzhong Lin, Jiaxing Zhang
BACKGROUND: MRI signal diffusion-weighted imaging (DWI) hyperintensity in the hippocampus in patients with transient global amnesia (TGA) are resolved within several days after the onset of TGA. PURPOSE: To use multiparametric MRI to unravel the sequelae of TGA. STUDY TYPE: A prospective longitudinal study. POPULATION: Eight TGA patients. FIELD STRENGTH/SEQUENCE: A 3.0T Siemens Tim Trio MRI scanner with T1 -weighted MPRAGE, diffusion-weighted echo planar imaging, and multiecho gradient-recalled echo sequences...
September 7, 2017: Journal of Magnetic Resonance Imaging: JMRI
https://www.readbyqxmd.com/read/28745847/transient-global-amnesia-emergency-department-evaluation-and-management-digest
#8
Jeremy Samuel Faust, Andreea Nemes, Milana Zaurova
Transient global amnesia is a clinically distinct syndrome characterized by the acute inability to form new memories. It can last up to 24 hours. The diagnosis is dependent on eliminating other more serious etiologies including toxic ingestions, acute strokes, complex partial seizures, and central nervous system infections. Transient global amnesia confers no known long-term risks; however, when abnormal signs or symptoms are present, they take precedence and guide the formulation of a differential diagnosis and investigation...
August 22, 2016: Emergency Medicine Practice
https://www.readbyqxmd.com/read/28710234/takotsubo-cardiomyopathy-and-transient-global-amnesia-a-shared-aetiology
#9
Jithin Sajeev, Anoop Koshy, Kevin Rajakariar, Gary Gordon
Takotsubo cardiomyopathy (TTC) is associated with acute, reversible left ventricular (LV) dysfunction, while transient global amnesia (TGA) is a reversible disorder of the brain characterised by anterograde amnesia. We report an unusual case of TTC occurring concurrently in a patient with TGA, and propose that catecholamine surge induced cerebral venous congestion and cardiotoxicity is the shared aetiology that leads to the concurrent manifestation of these conditions. TTC and TGA are reversible disorders that can occur concurrently in a subset of patients due to a unifying aetiology, catecholamine excess, leading to pathophysiological changes within the brain and the myocardium...
July 14, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28669658/vascular-risk-factors-and-internal-jugular-venous-flow-in-transient-global-amnesia-a-study-of-165-japanese-patients
#10
Takahiro Himeno, Masaru Kuriyama, Makoto Takemaru, Yuhei Kanaya, Yuji Shiga, Shinichi Takeshima, Kazuhiro Takamatsu, Yutaka Shimoe, Tomoko Fukushima, Etsuro Matsubara
BACKGROUND: The etiology of transient global amnesia (TGA) remains unclear. We studied the pathophysiology of TGA in 165 Japanese patients. SUBJECTS AND METHODS: TGA was diagnosed in hospitalized patients from 2004 to 2015. We analyzed clinical characteristics, magnetic resonance imaging findings, and maximum intima-media thickness of the common carotid artery, and the reflux of internal jugular venous (IJV) flow by ultrasonography, and statistically compared patients with TGA with age-matched and sex-matched patients who have had a transient ischemic attack (TIA), small-vessel occlusion (SVO), and normal controls (each group, N = 165)...
October 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28644249/incidental-hippocampal-hyperintensity-on-diffusion-weighted-mri-individual-susceptibility-to-transient-global-amnesia
#11
Moonyoung Jeong, Jaehyun Jin, Jeong Hee Kim, Yeonsil Moon, Jin Woo Choi, Hahn Young Kim
OBJECTIVES: Dot-like hippocampal hyperintensities (HHs) on diffusion-weighted MRI (DWI) have been reported as an interesting imaging finding of transient global amnesia (TGA) that is characterized by typical anterograde amnesia. However, we found that these dot-like HHs are occasionally seen in some patients without clinical symptoms of TGA. METHODS: We identified 8 patients who did not show clinical symptoms of TGA, despite the presence of hippocampal lesions on DWI (No-TGA group, n=8)...
July 2017: Neurologist
https://www.readbyqxmd.com/read/28626186/reversible-cerebral-vasoconstriction-syndrome-presenting-with-transient-global-amnesia
#12
Kenji Isahaya, Kensuke Shinohara, Masashi Akamatu, Takahiro Shimizu, Kenzo Sakurai, Makoto Shiraishi, Hisanao Akiyama, Yasuhiro Hasegawa
A 65-year-old man who had been diagnosed with transient global amnesia (TGA) 15 years previously was admitted to hospital with complaints of amnesia and headache. His symptoms improved on day-2. The initial brain MRI and electroencephalography findings were normal. He was diagnosed with a recurrence of TGA and discharged. However, he returned with right leg weakness and complained of a thunderclap headache. MRI demonstrated subarachnoid hemorrhage and multifocal segmental narrowing of the left posterior cerebral artery (PCA) and large intracranial arteries, and he was diagnosed with reversible cerebral vasoconstriction syndrome (RCVS)...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28611653/familial-retinal-arteriolar-tortuosity-with-acute-hippocampal-infarction
#13
Tae Hee Kim, Sonia Lee, Su Jin Lim
PURPOSE: To report a case of familial retinal arteriolar tortuosity with acute hippocampal infarction. METHOD: Single-patient case report. RESULTS: A 50-year-old woman presented with blurred vision and was found to have cataract, retinal hemorrhages, and tortuous retinal arterioles in both eyes. Similar findings of tortuous retinal arterioles were observed in her daughter and son. In her past history of 6 years prior to the visit, she had been diagnosed with transient global amnesia after brain magnetic resonance imaging, which showed hippocampal infarction and multiple chronic ischemic lesions in the periventricular and subcortical white matter...
January 2017: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/28584000/ischemic-amnesia-causes-and-outcome
#14
Patrik Michel, Valérie Beaud, Ashraf Eskandari, Philippe Maeder, Jean-François Demonet, Elissavet Eskioglou
BACKGROUND AND PURPOSE: We aimed to describe the frequency and characteristics of acute ischemic stroke and transient ischemic attacks presenting predominantly with amnesia (ischemic amnesia) and to identify clinical clues for differentiating them from transient global amnesia (TGA). METHODS: We retrospectively analyzed and described all patients presenting with diffusion-weighted imaging magnetic resonance imaging-confirmed acute ischemic stroke/transient ischemic attacks with antero- and retrograde amnesia as the main symptom over a 13...
August 2017: Stroke; a Journal of Cerebral Circulation
https://www.readbyqxmd.com/read/28552870/adult-onset-neuronal-intranuclear-inclusion-disease-presented-transient-global-amnesia-a-case-report
#15
Jun Takeshita, Hiromitsu Kobayashi, Yutaka Shimoe, Jun Sone, Gen Sobue, Masaru Kuriyama
A 65-year-old man had a transient amnesia for about 3 hours. Similar symptoms appeared three years ago. He did not manifest dementia, cerebellar ataxia and involuntary movements. Peripheral neuropathy was observed by the neurophysiological examinations. Diffusion weighted image showed high intensity signal in the area of the corticomedullary junction of the frontal to parietal lobes and immunohistochemical studies of biopsied skin revealed many intranuclear inclusion bodies. Adult-onset neuronal intranuclear inclusion disease was diagnosed...
June 28, 2017: Rinshō Shinkeigaku, Clinical Neurology
https://www.readbyqxmd.com/read/28549449/fatal-familial-insomnia-with-abnormal-signals-on-routine-mri-a-case-report-and-literature-review
#16
Tingting Lu, Yuhang Pan, Lisheng Peng, Feng Qin, Xiaobo Sun, Zhengqi Lu, Wei Qiu
BACKGROUND: Fatal familial insomnia (FFI) is a rare autosomal dominant disease caused by the PRNP D178N/129 M mutation. Routine brain CT and MRI usually reveal non-specific features. We report a patient with FFI presenting with diffuse abnormal signals on MRI, later confirmed as combined with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL). CASE PRESENTATION: The patient was a 58-year-old female, whose main clinical manifestations were insomnia, movement disorders, autonomic hyperactivity and mental deterioration...
May 26, 2017: BMC Neurology
https://www.readbyqxmd.com/read/28438578/global-cerebral-ischemia-in-rats-leads-to-amnesia-due-to-selective-neuronal-death-followed-by-astroglial-scar-formation-in-the-ca1-layer
#17
Kevin Sadelli, Jean-Claude Stamegna, Stéphane D Girard, Nathalie Baril, Guy Escoffier, Maïna Brus, Antoine D Véron, Michel Khrestchatisky, François S Roman
Global Cerebral Ischemia (GCI) occurs following cardiac arrest or neonatal asphyxia and leads to harmful neurological consequences. In most cases, patients who survive cardiac arrest develop severe cognitive and motor impairments. This study focused on learning and memory deficits associated with brain neuroanatomical reorganization that appears after GCI. The four-vessel occlusion (4VO) model was performed to produce a transient GCI. Hippocampal lesions in ischemic rats were visualized using anatomical Magnetic Resonance Imaging (aMRI)...
April 21, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28433970/simultaneous-transient-global-amnesia-and-right-mca-stroke-after-valsalva-manoeuvre
#18
Ariel Fernando Mariaca, Jose Manuel Valdueza, Christian Gaebel, Manuel Gomez-Choco
A 61-year-old man suffered an episode of transient confusion and anterograde amnesia after a Valsalva-related manoeuvre. The MRI diffusion weighted imaging (DWI) sequences showed a left hippocampal and two right parietal lesions that were deemed as acute. The MR angiography disclosed a high-grade stenosis in the right middle cerebral artery as was described by a transcranial colour-coded ultrasound as well. Ultrasound investigation of the jugular veins showed a right jugular venous reflux after a Valsalva manoeuvre...
April 22, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28405991/bilateral-reversible-diffusion-weighted-mri-abnormalities-in-transient-global-amnesia
#19
L Vinitha, George Jacob, P T Gourisankar
No abstract text is available yet for this article.
December 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28366339/prevalence-of-obstructive-sleep-apnea-syndrome-in-a-population-of-patients-with-transient-global-amnesia
#20
L Buratti, C Petrelli, E Potente, A Plutino, G Viticchi, L Falsetti, L Provinciali, M Silvestrini
OBJECTIVE: The etiology of transient global amnesia (TGA) is largely undetermined. The aim of this study was to investigate whether the prevalence of obstructive sleep apnea syndrome (OSAS), a condition associated with subtle changes in brain structures involved in memory processes, increases in subjects who have previously experienced a TGA episode. METHODS: Twenty-nine patients who had had a TGA episode were included. A case-control model was used, matching cases with controls by sex, age, and body mass index category...
April 2017: Sleep Medicine
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