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Pelvic lymph node dissection

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https://www.readbyqxmd.com/read/28916272/external-validation-of-the-pathologic-nodal-staging-score-for-prostate-cancer-a%C3%A2-population-based-study
#1
Malte Rieken, Luis A Kluth, Christian Seitz, Mohammad Abufaraj, Beat Foerster, Romain Mathieu, Pierre I Karakiewicz, Alexander Bachmann, Alberto Briganti, Morgan Rouprê, Mithat Gönen, Shahrokh F Shariat, Veronika Seebacher
BACKGROUND: We sought to externally validate our pathologic nodal staging score (pNSS) model, which allows for quantification of the likelihood that a pathologically node-negative patient will not have lymph node (LN) metastasis after radical prostatectomy for prostate cancer (PCa) in a population-based cohort. PATIENTS AND METHODS: We analyzed data from 50,598 patients treated with radical prostatectomy and pelvic LN dissection using the Surveillance, Epidemiology, and End Results database...
August 24, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28888228/transperineal-cryotherapy-for-unresectable-muscle-invasive-bladder-cancer-preliminary-experience-with-7-male-patients
#2
Qing Zhang, Shiwei Zhang, Shun Zhang, Wei Wang, Xiaozhi Zhao, Yongming Deng, Huibo Lian, Hongqian Guo
BACKGROUND: Radical cystectomy (RC) with pelvic lymph node dissection (PLND) and urinary diversion (UD) is considered the standard treatment for muscle invasive bladder cancer (MIBC). In a part of patients, RC procedure is aborted due to unresectable disease, other followed treatment like systemic chemotherapy, radiotherapy or cryotherapy may be a better option. The aim of present study was to report the preliminary results of transperineal cryotherapy for unresectable muscle invasive bladder cancer...
September 9, 2017: BMC Urology
https://www.readbyqxmd.com/read/28881693/predictive-factors-of-para-aortic-lymph-nodes-metastasis-in-cervical-cancer-patients-a-retrospective-analysis-based-on-723-para-aortic-lymphadenectomy-cases
#3
Xiaotian Han, Hao Wen, Xingzhu Ju, Xiaojun Chen, Guihao Ke, Yuqi Zhou, Jin Li, Lingfang Xia, Jia Tang, Shanhui Liang, Xiaohua Wu
Para-aortic lymph node (PALN) dissection is optional and controversial in patients with stage IB1-IIA2 cervical cancer. This retrospective study investigated PALN involvement patterns and evaluated preoperative clinical factors. A total of 723 consecutive FIGO stage IB1-IIA2 cervical cancer patients were included in the study. All patients underwent radical hysterectomy/radical trachelectomy, pelvic lymph node dissection, and PALN dissection. PALN metastasis was found in 101 (14.0%) patients, and the positive PALN rates of stage IB1, IB2, IIA1, and IIA2 were 8...
August 1, 2017: Oncotarget
https://www.readbyqxmd.com/read/28880495/case-report-of-perineal-hernia-after-laparoscopic-abdominoperineal-resection
#4
Kumpei Honjo, Kazuhiro Sakamoto, Shunsuke Motegi, Ryoichi Tsukamoto, Shinya Munakata, Kiichi Sugimoto, Hirohiko Kamiyama, Makoto Takahashi, Yutaka Kojima, Tetsu Fukunaga, Yoshiaki Kajiyama, Seiji Kawasaki
Perineal hernia (PH) is a rare complication following laparoscopic abdominoperineal resection (APR) for rectal cancer. We present a case report of perineal hernia after laparoscopic APR and discuss its management. The patient was a 77-year-old man who was diagnosed with lower rectal cancer. He underwent laparoscopic APR and bilateral lateral lymph node dissection. Two months after the surgery, pain and bulging in the perineal region developed, and PH was diagnosed by CT. Repair with a polypropylene mesh was performed using a combination of laparoscopic abdominal and transperineal approaches...
September 7, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28875611/oncologic-outcomes-and-predictive-factors-for-recurrence-following-robot-assisted-radical-cystectomy-for-urothelial-carcinoma-multicenter-study-from-korea
#5
Ji Sung Shim, Tae Gyun Kwon, Koon Ho Rha, Young Goo Lee, Ji Youl Lee, Byong Chang Jeong, Jae Yoon Kim, Jong Hyun Pyun, Sung Gu Kang, Seok Ho Kang
The aim of our study was to evaluate intermediate-term oncologic outcomes, predictive factors for recurrence, and recurrence patterns in a multicenter series of patients treated with robot-assisted radical cystectomy (RARC) for urothelial carcinoma (UC) of the bladder. Between 2007 and 2015, 346 patients underwent RARC at multiple tertiary referral centers in Korea. Descriptive statistics were used for demographics and perioperative variables. Survival and recurrence were estimated with Kaplan-Meier analysis...
October 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/28873443/application-of-carbon-nanoparticles-in-laparoscopic-sentinel-lymph-node-detection-in-patients-with-early-stage-cervical-cancer
#6
Yan Lu, Jin-Ying Wei, De-Sheng Yao, Zhong-Mian Pan, Yao Yao
OBJECTIVE: To investigate the value of carbon nanoparticles in identifying sentinel lymph nodes in early-stage cervical cancer. METHODS: From January 2014 to January 2016, 40 patients with cervical cancer stage IA2-IIA, based on the International Federation of Gynecology and Obstetrics (FIGO) 2009 criteria, were included in this study. The normal cervix around the tumor was injected with a total of 1 mL of carbon nanoparticles (CNP)at 3 and 9 o'clock. All patients then underwent laparoscopic pelvic lymph node dissection and radical hysterectomy...
2017: PloS One
https://www.readbyqxmd.com/read/28872774/prospective-randomized-non-inferiority-trial-of-pelvic-drain-placement-versus-no-pelvic-drain-placement-after-robot-assisted-radical-prostatectomy
#7
Avinash Chenam, Bertram Yuh, Ali Zhumkhawala, Nora Ruel, William Chu, Clayton Lau, Kevin Chan, Timothy Wilson, Jonathan Yamzon
OBJECTIVES: To determine if eliminating the prophylactic placement of a pelvic drain (PD) after robot-assisted radical prostatectomy (RARP) affects the incidence of early (90-day) postoperative adverse events. MATERIALS AND METHODS: In this parallel-group, blinded, non-inferiority trial, we randomized patients planning to undergo RARP to one of two arms: no drain placement (ND) or PD placement. Patients with demonstrable intra-operative leakage upon bladder irrigation were excluded...
September 5, 2017: BJU International
https://www.readbyqxmd.com/read/28870939/clinical-and-oncological-outcomes-of-laparoscopic-lateral-pelvic-lymph-node-dissection-in-advanced-lower-rectal-cancer-single-institution-experience
#8
Takashi Nonaka, Akiko Fukuda, Kyoichiro Maekawa, Shigeki Nagayoshi, Takayuki Tokunaga, Mitsutoshi Takatsuki, Tomoo Kitajima, Ken Taniguchi, Hikaru Fujioka
AIM: The aim of this study was to compare the clinical outcomes of laparoscopic versus open surgery for total mesorectal excision (TME) with lateral pelvic lymph node dissection (LPLD) in advanced lower rectal cancer. PATIENTS AND METHODS: Forty-four patients who underwent TME with LPLD for lower rectal cancer (pStage II/III) between January 2008 and December 2014 were divided into two groups according to the type of surgical approach as follows: open LPLD group (OLD, n=17) and laparoscopic LPLD group (LLD, n=27)...
September 2017: Anticancer Research
https://www.readbyqxmd.com/read/28866431/outcomes-of-stage-ii-endometrial-cancer-the-upmc-hillman-cancer-center-experience
#9
Katherine S Chen, Hebist Berhane, Beant S Gill, Alexander Olawaiye, Paniti Sukumvanich, Joseph L Kelley, Michelle M Boisen, Madeleine Courtney-Brooks, John T Comerci, Robert Edwards, Jessica Berger, Sushil Beriwal
PURPOSE: Previous studies of stage II endometrial cancer have included cancers with cervical glandular involvement, a factor no longer associated with risk of recurrence. In order to better assess relapse patterns and the impact of adjuvant therapy, a retrospective analysis was conducted for patients with modern stage II endometrial cancer, defined as cervical stromal invasion. MATERIALS AND METHODS: Patients diagnosed with surgically staged FIGO stage II endometrial cancer at the UPMC Hillman Cancer Center from 1990-2013 were reviewed...
August 30, 2017: Gynecologic Oncology
https://www.readbyqxmd.com/read/28866245/incidence-and-effect-of-thromboembolic-events-in-radical-cystectomy-patients-undergoing-preoperative-chemotherapy-for-muscle-invasive-bladder-cancer
#10
Aditya Bagrodia, Ranjit Sukhu, Andrew G Winer, Eric Levy, Michael Vacchio, Byron Lee, Eugene J Pietzak, Timothy F Donahue, Eugene Cha, Gopa Iyer, Daniel D Sjoberg, Andrew J Vickers, Jonathan E Rosenberg, Dean F Bajorin, Guido Dalbagni, Bernard H Bochner
BACKGROUND: We evaluated the incidence and effect of thromboembolic events (TEEs) in patients with muscle-invasive bladder cancer treated with preoperative chemotherapy (POC) and radical cystectomy (RC) with pelvic lymph node dissection (PLND). PATIENTS AND METHODS: We performed a retrospective review of all patients who had undergone POC followed by RC plus PLND for muscle-invasive bladder cancer from June 2000 to January 2013 (n = 357). The chemotherapy type (neoadjuvant vs...
August 10, 2017: Clinical Genitourinary Cancer
https://www.readbyqxmd.com/read/28862047/new-surgical-approaches-for-clinically-high-risk-or-metastatic-prostate-cancer
#11
Paolo Dell'Oglio, Armando Stabile, Giorgio Gandaglia, Emanuele Zaffuto, Nicola Fossati, Marco Bandini, Nazareno Suardi, Pierre I Karakiewicz, Shahrokh F Shariat, Francesco Montorsi, Alberto Briganti
A considerable number of individuals with prostate cancer (PCa) still harbor locally-advanced and metastatic disease. Although such men were initially not considered eligible for local treatment, the role of radical prostatectomy (RP) has been recently reassessed. Areas covered: This review analyses currently published evidences regarding new surgical approaches for clinically high-risk PCa individuals, as well as the role of cytoreductive surgery in the metastatic setting. The role of robot-assisted radical prostatectomy (RARP) and extended pelvic lymph node dissection will be evaluated with regards to perioperative, oncologic, as well as functional outcomes...
September 11, 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28852347/marjolin-s-ulcer-of-the-tibia-with-pelvic-lymph-node-metastasis
#12
Craig C Akoh, Justin Chang, Joseph Buckwalter
Marjolin's ulcer, a form of squamous cell carcinoma, is a rare complication of a chronic wound infection. To date, there have not been any detailed reports of lymphatic spread of Marjolin's ulcer from an extremity. This report describes a 44-year old male with a history of an open tibia fracture at age 15, who presented with chronic osteomyelitis, increasing bloody wound drainage, and an enlarging vascular exophytic masses in the region of drainage. Biopsy of the mass showed squamous cell carcinoma. Initial staging with computed tomography (CT) was negative for metastatic disease...
2017: Iowa Orthopaedic Journal
https://www.readbyqxmd.com/read/28845943/-laparoscopic-cystoprostatvesiculeectomy-with-orthotopic-excentric-ileal-bladder-substitution
#13
P V Glybochko, Yu G Alyaev, E V Shpot', A M Pshi-Khachev, K M Mosyakova, A S Nikolaeva
There are numerous options for forming an orthotopic bladder by the source tissue and the shape of the urinary reservoir. In our practice, we use the technique reported by Karolinska Institute (Sweden). This technique allows us to form a neobladder most resembling the natural urinary bladder in the shape and volume. The article presents a clinical observation describing this technique in a 63 year old patient who was initially diagnosed with bladder cancer pT2N0M0G3 and underwent transurethral resection of the bladder wall with the tumor...
July 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28840384/survival-benefit-of-pelvic-and-paraaortic-lymphadenectomy-in-high-grade-endometrial-carcinoma-a-retrospective-population-based-cohort-analysis
#14
Thomas Papathemelis, S Scharl, K Kronberger, M Gerken, A Scharl, A Pauer, M Klinkhammer-Schalke
OBJECTIVE: The standard therapy for high-grade endometrial cancer is surgery but the therapeutic effects of pelvic and paraaortic lymph node dissection (LND) are poorly investigated. In this study, we retrospectively evaluated overall survival, recurrence rates and recurrence-free survival among patients with high-grade type I and II endometrial carcinoma who underwent LND. METHODS: This study included 284 patients who are recorded in the German Tumor Centre Regensburg form 1998 to 2015 and were selected by cancer grading, the absence of secondary tumors, primary surgery including hysterectomy and available follow-up...
August 24, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28834085/a-more-extended-lymph-node-dissection-template-at-radical-prostatectomy-detects-metastases-in-the-common-iliac-region-and-in-the-fossa-of-marcille
#15
Lydia Maderthaner, Marc A Furrer, Urs E Studer, Fiona C Burkhard, George N Thalmann, Daniel P Nguyen
OBJECTIVES: To assess the effect of adding lymph nodes (LN) located along the common iliac vessels and in the fossa of Marcille to the extended pelvic lymph node dissection (PLND) template at radical prostatectomy (RP). PATIENTS AND METHODS: At a referral center, RP and PLND were undergone by 485 patients from 2000 to 2008 (historical cohort: classical extended PLND template) and 268 patients from 2010 to 2015 (contemporary cohort: extended PLND template including LN located along the common iliac vessels and in the fossa of Marcille)...
August 21, 2017: BJU International
https://www.readbyqxmd.com/read/28828530/long-term-oncological-outcomes-in-patients-with-limited-nodal-disease-undergoing-radical-prostatectomy-and-pelvic-lymph-node-dissection-without-adjuvant-treatment
#16
Philipp Mandel, Clemens Rosenbaum, Raisa S Pompe, Thomas Steuber, Georg Salomon, Felix K Chun, Markus Graefen, Hartwig Huland, Derya Tilki
PURPOSE: This study aimed at analysing long-term oncologic outcomes in prostate cancer patients with limited nodal disease (1-2 positive lymph nodes) without adjuvant therapy after radical prostatectomy (RP). METHODS: We retrospectively analysed data of 209 pN1 patients who underwent RP between January 1998 and 2010 with one (160) or two (49) histologically proven positive lymph nodes (LNs) without adjuvant treatment. Biochemical recurrence-free survival, metastasis-free survival and cancer-specific survival (CSS) were reported...
August 21, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/28827843/the-passive-biomechanics-of-human-pelvic-collecting-lymphatic-vessels
#17
Dimitrios Athanasiou, Lowell T Edgar, Mohammad Jafarnejad, Katherine Nixon, Delfim Duarte, Edwin D Hawkins, Samira Jamalian, Paula Cunnea, Cristina Lo Celso, Shunichi Kobayashi, Christina Fotopoulou, James E Moore
The lymphatic system has a major significance in the metastatic pathways in women's cancers. Lymphatic pumping depends on both extrinsic and intrinsic mechanisms, and the mechanical behavior of lymphatic vessels regulates the function of the system. However, data on the mechanical properties and function of human lymphatics are lacking. Our aim is to characterize, for the first time, the passive biomechanical behavior of human collecting lymphatic vessels removed at pelvic lymph node dissection during primary debulking surgeries for epithelial ovarian cancer...
2017: PloS One
https://www.readbyqxmd.com/read/28820475/epcam-expression-in-lymph-node-metastases-of-urothelial-cell-carcinoma-of-the-bladder-a-pilot-study
#18
Christa A M van der Fels, Stefano Rosati, Igle J de Jong
In this retrospective pilot study, the feasibility of the epithelial cell adhesion molecule (EpCAM) as an imaging target for lymph node (LN) metastatic disease of urothelial cell carcinoma (UCC) of the bladder was investigated. LN metastases and LNs without metastases of patients who underwent pelvic lymph node dissection because of muscle invasive bladder cancer (MIBC) were used. Primary tumors of the same patients were used from cystectomy specimen, transurethral resections, and biopsies. A pathologist, blinded to clinical data, scored EpCAM immunoreactivity...
August 18, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28808931/robotic-total-pelvic-exenteration-video-illustrated-technique
#19
Ioannis T Konstantinidis, William Chu, Federico Tozzi, Clayton Lau, Mark Wakabayashi, Kevin Chan, Byrne Lee
BACKGROUND: Robotic-assisted total pelvic exenteration (TPE) can offer a minimally invasive approach to a major multi-organ operation. METHODS: In this video, we summarize a stepwise approach to robotic TPE in a 70 year-old female Jehovah's witness with a history of cervical cancer post-chemoradiation and radical hysterectomy who experienced local recurrence at the vaginal cuff involving the rectum and bladder. RESULTS: The patient was placed in the lithotomy position...
August 14, 2017: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/28780722/validation-and-head-to-head-comparison-of-three-nomograms-predicting-probability-of-lymph-node-invasion-of-prostate-cancer-in-patients-undergoing-extended-and-or-sentinel-lymph-node-dissection
#20
Nikolaos Grivas, Esther Wit, Corinne Tillier, Erik van Muilekom, Floris Pos, Alexander Winter, Henk van der Poel
PURPOSE: The updated Winter nomogram is the only nomogram predicting lymph node invasion (LNI) in prostate cancer (PCa) patients based on sentinel node (SN) dissection (sLND). The aim of the study was to externally validate the Winter nomogram and examine its performance in patients undergoing extended pelvic lymph node dissection (ePLND), ePLND combined with SN biopsy (SNB) and sLND only. The results were compared with the Memorial Sloan Kettering Cancer Center (MSKCC) and updated Briganti nomograms...
August 5, 2017: European Journal of Nuclear Medicine and Molecular Imaging
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