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Pelvic lymph node dissection

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https://www.readbyqxmd.com/read/27909616/is-extended-pelvic-lymph-node-dissection-for-prostate-cancer-the-only-recommended-option-a-systematic-over-view-of-the-literature
#1
REVIEW
Thomas Rees, Nicholas Raison, Mohammed Iqbal Sheikh, Zahra Jaffry, Sanjeev Madaan, Ben Challacombe, Kamran Ahmed, Prokar Dasgupta
OBJECTIVE: Pelvic lymph node dissection (PLND) is performed alongside radical prostatectomy as the most accurate method of staging prostate cancer. Yet the potential therapeutic benefits of lymphadenectomy are yet to be confirmed. MATERIAL AND METHODS: A PubMed database search was performed to identify all papers comparing techniques for PLND or none. The primary outcome measure was long term oncological outcomes. Studies looking at men with clinically localized prostate cancer at the time of radical prostatectomy who received no adjuvant treatment were included...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27909613/the-novel-laparoscopic-training-3d-model-in-urology-with-surgical-anatomic-remarks-fresh-frozen-cadaveric-tissue
#2
REVIEW
Emre Huri, Mehmet Ezer, Eddie Chan
Laparoscopic surgery is routinely used to treat many urological conditions and it is the gold standard treatment option for many surgeries such as radical nephrectomy. Due to the difficulty of learning, laparoscopic training should start outside the operating room. Although it is a very different model of laparoscopic training; the aim of this review is to show the value of human cadaveric model for laparoscopic training and present our experience in this area. Fresh frozen cadaveric model in laparoscopic training, dry lab, cadaveric model, animal models and computer based simulators are the most commonly used models for laparoscopic training...
December 2016: Turkish Journal of Urology
https://www.readbyqxmd.com/read/27906676/role-of-systematic-lymphadenectomy-as-part-of-primary-debulking-surgery-for-optimally-cytoreduced-advanced-ovarian-cancer-reappraisal-in-the-era-of-radical-surgery
#3
Kyung Jin Eoh, Jung-Yun Lee, Jung Won Yoon, Eun Ji Nam, Sunghoon Kim, Sang-Wun Kim, Young Tae Kim
The prognostic significance of pelvic and para-aortic lymphadenectomy during primary debulking surgery for advanced-stage ovarian cancer remains unclear. This study aimed to evaluate the survival impact of lymph node dissection (LND) in patients treated with optimal cytoreduction for advanced ovarian cancer. Data from 158 consecutive patients with stage IIIC-IV disease who underwent optimal cytoreduction (<1 cm) were obtained via retrospective chart review. Patients were classified into two groups: (1) lymph node sampling (LNS), node count <20; and (2) LND, node count ≥20...
November 29, 2016: Oncotarget
https://www.readbyqxmd.com/read/27896578/is-there-evidence-for-a-close-connection-between-side-of-intravesical-tumor-location-and-ipsilateral-lymphatic-spread-in-lymph-node-positive-bladder-cancer-patients-at-radical-cystectomy-results-of-the-prometrics-2011-database
#4
M May, C Protzel, M W Vetterlein, M Gierth, J Noldus, A Karl, T Grimm, B Wullich, M O Grimm, P Nuhn, P J Bastian, J Roigas, B Hadaschik, C Gilfrich, M Burger, M Fisch, S Brookman-May, A Aziz, O W Hakenberg
PURPOSE: To evaluate the possible association between bladder tumor location and the laterality of positive lymph nodes (LN) in a prospectively collected multi-institutional radical cystectomy (RC) series. METHODS: The study population included 148 node-positive bladder cancer (BC) patients undergoing RC and pelvic lymph node dissection in 2011 without neoadjuvant chemotherapy and without distant metastasis. Tumor location was classified as right, left or bilateral and compared to the laterality of positive pelvic LN...
November 28, 2016: International Urology and Nephrology
https://www.readbyqxmd.com/read/27889880/the-impact-of-extended-lymph-node-dissection-versus-neoadjuvant-therapy-with-limited-lymph-node-dissection-on-biochemical-recurrence-in-high-risk-prostate-cancer-patients-treated-with-radical-prostatectomy-a-multi-institutional-analysis
#5
Takuma Narita, Takuya Koie, Teppei Ookubo, Koji Mitsuzuka, Shintaro Narita, Hayato Yamamoto, Takamitsu Inoue, Shingo Hatakeyama, Sadafumi Kawamura, Tatsuo Tochigi, Tomonori Habuchi, Yoichi Arai, Chikara Ohyama
The optimal treatment for high-risk prostate cancer (Pca) remains to be established. The current guidelines recommend extended pelvic lymph node dissection (e-PLND) for selected intermediate- and high-risk patients treated with RP. However, the indications, optimal extent, and therapeutic benefits of e-PLND remain unclear. The aim of this study was to assess whether e-PLND confers an oncological benefit for high-risk Pca compared to neoadjuvant luteinizing hormone-releasing hormone and estramustine (LHRH + EMP)...
January 2017: Medical Oncology
https://www.readbyqxmd.com/read/27884514/less-radical-surgery-for-early-stage-cervical-cancer-can-conization-specimens-help-identify-patients-at-low-risk-for-parametrial-involvement
#6
Blair Smith, Georgia A McCann, Gary Phillips, Floor J Backes, David M O'Malley, David E Cohn, Jeffrey M Fowler, Larry J Copeland, Ritu Salani
OBJECTIVE: Radical hysterectomy for cervical cancer is associated with increased morbidity over an extrafascial hysterectomy. The goal of this study was to determine incidence of and risk factors for parametrial involvement (PI) based on conization specimen (CS) and to potentially identify candidates for less radical surgery. METHODS: Patients with FIGO IA2-IIA cervical cancer treated with radical hysterectomy and pelvic lymph node dissection (RH) from 2000 to 2010 were retrospectively identified...
November 21, 2016: Gynecologic Oncology
https://www.readbyqxmd.com/read/27884204/lateral-pelvic-lymph-node-dissection-after-neoadjuvant-chemo-radiation-for-preoperative-enlarged-lateral-nodes-in-advanced-low-rectal-cancer-study-protocol-for-a-randomized-controlled-trial
#7
Mingtian Wei, Qingbin Wu, Chuanwen Fan, Yan Li, Xiangzheng Chen, Zongguang Zhou, Junhong Han, Ziqiang Wang
BACKGROUND: Lateral lymph node (LLN) metastasis is a major cause of local recurrence of advanced rectal cancer. Although there is much controversy between Western and Eastern countries on whether lateral pelvic lymph node dissection (LLND) or neoadjuvant chemo-radiation (nCRT) is preferable for the treatment of LLN metastases, existing retrospective cohorts mainly focus on all middle/low advanced rectal cancer patients, not the specific individuals with suspicion of LLN metastases. The aim of this trial is to assess the efficacy and safety of LLND for rectal cancer patients with suspicion of LLN metastases...
November 25, 2016: Trials
https://www.readbyqxmd.com/read/27882746/-technique-of-pelvic-and-paraaortic-lymphadenectomy
#8
J Sláma, R Kocián
OBJECTIVE: Overview of classification, anatomical conditions, methods and complications of pelvic and paraaortic lymph-node dissection. DESIGN: Review article. SETTING: Department of Obstetrics and Gynecology, General Faculty Hospital and 1st Medical Faculty, Charles University, Prague. MATERIALS AND METHODS: Lymphadenectomy is classified according to its extent into sentinel lymph-node biopsy, debulking, sampling and systematic procedure and according to approach into extraperitoneal or transperitoneal procedure...
2016: Ceská Gynekologie
https://www.readbyqxmd.com/read/27878050/suboptimal-use-of-pelvic-lymph-node-dissection-differences-in-guideline-adherence-between-robot-assisted-and-open-radical-prostatectomy
#9
Jonas Schiffmann, Alessandro Larcher, Maxine Sun, Zhe Tian, Jérémie Berdugo, Ion Leva, Hugues Widmer, Jean-Baptiste Lattouf, Kevin C Zorn, Shahrokh F Shariat, Francesco Montorsi, Markus Graefen, Fred Saad, Pierre I Karakiewicz
INTRODUCTION: Our aim was to assess adherence to National Comprehensive Cancer Network (NCCN) and American Urological Association (AUA) guidelines for pelvic lymph node dissection (PLND) at the time of either robot-assisted (RARP) or open radical prostatectomy (ORP). METHODS: We relied on the Surveillance, Epidemiology, and End Results-Medicare linked database and focused on localized prostate cancer (PCa) patients who were treated with either RARP or ORP between October 2008 and December 2009...
August 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27867048/feasibiility-and-learning-curve-of-robotic-laparo-endoscopic-single-site-surgery-in-gynecology
#10
Alexandre Buckley de Meritens, Julia Kim, Helen Dinkelspiel, Eloise Chapman-Davis, Thomas Caputo, Kevin Holcomb
Single-site laparoscopy has proven to be a desirable option for patients undergoing gynecologic surgery with some studies indicating improved cosmesis and less perioperative pain compared to standard approaches. This study describes the safety and feasibility of a novel robotic laparo-endoscopic single-site surgery (R-LESS) platform as it is incorporated into a surgeon's practice with extensive multiport robotic surgical experience but limited laparo-endoscopic single-site experience. We reviewed 83 women undergoing R-LESS by a single surgeon from September 2013 through August 2015...
November 17, 2016: Journal of Minimally Invasive Gynecology
https://www.readbyqxmd.com/read/27859018/the-role-of-adjuvant-radiotherapy-in-pathologically-lymph-node-positive-prostate-cancer
#11
Naresh Jegadeesh, Yuan Liu, Chao Zhang, Jim Zhong, Richard J Cassidy, Theresa Gillespie, Omer Kucuk, Peter Rossi, Viraj A Master, Mehrdad Alemozaffar, Ashesh B Jani
BACKGROUND: Postoperative management of prostate cancer with lymph node involvement (LNI) is controversial. Retrospective evidence supports the selective use of radiotherapy (RT) after extended pelvic lymph node dissection. It is unclear whether this is generalizable to practice in the United States, where extended dissection is uncommon. The authors identified patients with LNI who potentially could derive a survival benefit with adjuvant RT plus androgen-deprivation therapy (ADT). METHODS: Patients with N1M0 prostate adenocarcinoma who underwent radical prostatectomy (RP) and subsequently received ADT from 2003 through 2011 were identified from the National Cancer Database...
November 8, 2016: Cancer
https://www.readbyqxmd.com/read/27843216/the-peritoneal-scaffold-technique-of-extended-pelvic-lymph-node-dissection-during-radical-prostatectomy-a-novel-technique
#12
Chiruvella Mallikarjuna, Prasant Nayak, Syed Mohammed Ghouse, K Purnachandra Reddy, Deepak Reddy Ragoori, M T Bendigeri, Siva Reddy
INTRODUCTION: Laparoscopic or robotic-assisted laparoscopic radical prostatectomy (RALP) is a frequently used approach for localized carcinoma prostate. For intermediate and high-risk cancers, extended pelvic lymph node dissection (e-PLND), is often performed. Conventional e-PLND involves piecemeal retrieval of lymphatic tissue. We describe a novel technique of laparoscopic e-PLND, which involves en-masse removal of pelvic lymph nodes from each side, based on an overlying peritoneal scaffold...
October 2016: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/27830926/comparing-conventional-laparoscopic-to-robotic-assisted-extended-pelvic-lymph-node-dissection-in-men-with-intermediate-and-high-risk-prostate-cancer-a-matched-pair-analysis
#13
Simone Albisinni, Fouad Aoun, Dam LE Dinh, Marc Zanaty, Eric Hawaux, Alexandre Peltier, Roland VAN Velthoven
BACKGROUND: In intermediate and high-risk prostate cancer patients, a robotic-assisted approach is increasingly being used for prostatectomy and extended pelvic lymph node dissection (ePLND). This is reducing the number of conventional laparoscopic radical prostatectomies (LRP) and laparoscopic ePLNDs for prostate cancer in Europe. Aim of this study is to compare laparoscopic ePLND to robotic-assisted ePLND in a cohort of patients with intermediate and high risk prostate cancer. METHODS: We performed a matched-pair analysis matching 1:1 70 patients who underwent LRP+ePLND (2004-2009) to 70 who underwent RARP+ePLND (2010-2014)All patients presented with intermediate or high-risk prostate cancer according to D'Amico classification...
November 10, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/27824248/robot-assisted-lymphadenectomy-in-urology-pelvic-retroperitoneal-and-inguinal-a-systematic-review
#14
Giovannalberto Pini, Surena F Matin, Nazareno Suardi, Mihir Desai, Inderbir Gill, James Porter, Robert J Stein, Rene Sotelo, Franco Gaboardi, Francesco Porpiglia
Lymph node dissection represents an essential surgical step in the treatment of the most commonly treated urological cancers. The introduction of robotic surgery has lead to the possibility of treating these diseases with a minimally invasive surgical approach, but the surgical principles of open surgery need to be carefully respected in order to achieve comparable oncological results. Therefore, the robotic approach to urological cancers must include a carefully performed lymph node dissection when indicated...
November 8, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
https://www.readbyqxmd.com/read/27817158/a-pet-mri-study-towards-finding-the-optimal-18-f-fluciclovine-pet-protocol-for-detection-and-characterisation-of-primary-prostate-cancer
#15
Mattijs Elschot, Kirsten M Selnæs, Elise Sandsmark, Brage Krüger-Stokke, Øystein Størkersen, May-Britt Tessem, Siver A Moestue, Helena Bertilsson, Tone F Bathen
PURPOSE: [(18)F]Fluciclovine PET imaging shows promise for the assessment of prostate cancer. The purpose of this PET/MRI study is to optimise the PET imaging protocol for detection and characterisation of primary prostate cancer, by quantitative evaluation of the dynamic uptake of [(18)F]Fluciclovine in cancerous and benign tissue. METHODS: Patients diagnosed with high-risk primary prostate cancer underwent an integrated [(18)F]Fluciclovine PET/MRI exam before robot-assisted radical prostatectomy with extended pelvic lymph node dissection...
November 5, 2016: European Journal of Nuclear Medicine and Molecular Imaging
https://www.readbyqxmd.com/read/27807725/unilateral-pelvic-side-wall-lymph-node-resection-for-rectal-cancer-a-review-of-the-anatomy
#16
Tian-Zhi Lim, Peter J Lee, Michael J Solomon, Ker-Kan Tan
BACKGROUND: The aim of this video is to highlight key safety and critical techniques employed during laparoscopic pelvic side-wall lymph node resection for rectal cancer. In addition, a review of the key pelvic side-wall anatomical structures will be included. METHODS: We report a case of a 50-year-old Chinese female who presented with per-rectal bleeding, with colonoscopy revealing a 1.5 cm moderately differentiated rectal adenocarcinoma 4 cm above the anorectal junction...
November 2, 2016: Annals of Surgical Oncology
https://www.readbyqxmd.com/read/27797436/radio-guided-sentinel-lymph-node-detection-and-lymph-node-mapping-in-invasive-urinary-bladder-cancer-a-prospective-clinical-study
#17
F Aljabery, I Shabo, Hans Olson, Oliver Gimm, Staffan Jahnson
OBJECTIVES: We investigated the possibility to detect sentinel nodes in patients with urinary bladder cancer (UBC) intra-operatively and whether the histopathological status of the identified sentinel nodes reflected that of the lymphatic field. PATIENTS AND METHODS: We studied 103 patients with UBC pathological stage T1-T4 who were treated with cystectomy and pelvic lymph node (LN) dissection during 2005-2011 at the Department of Urology, Linköping University Hospital...
October 31, 2016: BJU International
https://www.readbyqxmd.com/read/27790636/papillary-squamous-cell-carcinoma-of-the-cervix-two-cases-and-a-review-of-the-literature
#18
Lauren B Turker, Gregory M Gressel, Maria Abadi, Marina Frimer
OBJECTIVE: Papillary squamous cell carcinoma of the cervix (PSCC) is a rare and distinct form of cervical carcinoma. Detecting stromal invasion on biopsy is difficult due to the papillary growth of the tumor. Here we present two cases that highlight the diagnostic and clinical challenges of PSCC. CASE 1: A 50-year-old woman found to have carcinoma on a routine pap-smear. The patient was diagnosed with PSCC on colposcopic biopsy and underwent a radical hysterectomy, bilateral salpingo-oophorectomy and pelvic lymph node dissection...
November 2016: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/27785427/adjuvant-radiotherapy-for-pathological-high-risk-muscle-invasive-bladder-cancer-time-to-reconsider
#19
REVIEW
Paul Sargos, Brian C Baumann, Libni J Eapen, Amit Bahl, Vedang Murthy, Guilhem Roubaud, Mathieu Orré, Jason A Efstathiou, Shahrokh Shariat, Stephane Larré, Pierre Richaud, John P Christodouleas
Radical cystectomy with extended pelvic lymph-node dissection, associated with neo-adjuvant chemotherapy, remains the standard of care for advanced, non-metastatic muscle-invasive bladder cancer (MIBC). Loco-regional control is a key factor in the outcome of patients since it is related to overall survival (OS), disease-free survival (DFS) and cause-specific survival. The risk of loco-regional recurrence (LRR) is correlated to pathological factors as well as the extent of the lymphadenectomy. In addition, neither pre- nor post-operative chemotherapy have shown a clear impact on LRR-free survival...
October 2016: Translational Andrology and Urology
https://www.readbyqxmd.com/read/27785420/why-are-upper-tract-urothelial-carcinoma-two-different-diseases
#20
REVIEW
Tibor Szarvas, Orsolya Módos, András Horváth, Péter Nyirády
In the last few years growing evidence highlighted the differences between upper tract urothelial carcinoma (UTUC) and urothelial bladder carcinoma (UBC) which cannot be explained solely by their different anatomical location. The aim of this review was to summarize current progress in UTUC research and to underline the differences and similarities between UTUC and UBC by focusing on epidemiology, etiology, staging and risk factors as well as on surgical and medical management. UBC and UTUC sharing common risk factors such as smoking and aromatic amines, while aristolochic acid exposure or familiar Lynch syndrome are rather specific for UTUC...
October 2016: Translational Andrology and Urology
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