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Pelvic lymph node dissection

Vanessa Rigaud, Pengfei Wang, Ashley Bartalot, Farr Nezhat
Iliopsoas abscess (IPA) is a rare condition seen in a variety of specialties that presents with nonspecific complaints. Presented herein is the development of an IPA after robotic staging with sentinel lymaphadenectomy for endometrial carcinoma. Patient is a 61yo female with history of prolonged immunosuppressive therapy due to psoriasis. She presented with an IPA, eight weeks after a robotic-assisted laparoscopic hysterectomy, BSO, and sentinel lymph node dissection. The patient was treated and cured with empiric antibiotics and IR drainage...
November 13, 2017: Journal of Minimally Invasive Gynecology
Marco Bandini, Michele Marchioni, Raisa S Pompe, Zhe Tian, Giorgio Gandaglia, Nicola Fossati, Firas Abdollah, Markus Graefen, Francesco Montorsi, Fred Saad, Shahrokh F Shariat, Alberto Briganti, Pierre I Karakiewicz
OBJECTIVES: To perform a head-to-head comparison of four nomograms, namely the Cagiannos, the 2012-Briganti, the Godoy and the online-Memorial Sloan Kettering Cancer Center (MSKCC), for prediction of lymph node invasion (LNI) in a North American population. MATERIALS & METHODS: 19,775 clinically localized prostate cancer (PCa) patients underwent radical prostatectomy and pelvic lymph node dissection (PLND) were identified within the Surveillance Epidemiology and End Results (SEER) database...
November 10, 2017: BJU International
Hye Jin Kim, Gyu-Seog Choi, Jun Seok Park, Soo Yeun Park, Hee Jae Lee, In Taek Woo, In Kyu Park
BACKGROUND: Lateral pelvic lymph node dissection (LPND) is a challenging procedure due to its technical difficulty and higher incidence of surgical morbidity. We compared short-term outcomes between laparoscopic and robotic LPND in patients with rectal cancer. METHODS: Between May 2006 and December 2014, prospectively collected data from consecutive patients undergoing robotic or laparoscopic total mesorectal excision (TME) with LPND were retrospectively compared...
November 9, 2017: Surgical Endoscopy
Jack Crozier, Nathan Papa, Marlon Perera, Michael Stewart, Jeremy Goad, Shomik Sengupta, Damien Bolton, Nathan Lawrentschuk
Purpose: To determine the oncological implications of increased nodal dissection in node-negative bladder cancer during radical cystectomy in a contemporary Australian series. Materials and Methods: We performed a multicenter retrospective study, including more than 40 surgeons across 5 sites over a 10-year period. We identified 353 patients with primary bladder cancer undergoing radical cystectomy. Extent of lymphadenectomy was defined as follows; limited pelvic lymph node dissection (PLND) (perivesical, pelvic, and obturator), standard PLND (internal and external iliac) and extended PLND (common iliac)...
November 2017: Investigative and Clinical Urology
J W Yaxley, J Dagher, B Delahunt, L Egevad, J Srigley, H Samaratunga
BACKGROUND: Performing an extended pelvic lymph node dissection (PLND) on all men with intermediate- and high-risk prostate cancer at the time of a radical prostatectomy (RP) remains controversial. The majority of patients PLND histology is benign, and the long-term cancer-free progression in men with positive lymph node metastasis is low. The objective is to investigate the probability of long-term biochemical freedom from recurrent disease (bNED) in men with lymph node metastasis identified at the time of radical prostatectomy (RP)...
November 7, 2017: World Journal of Urology
Qing Zhang, Shiming Zang, Chengwei Zhang, Yao Fu, Xiaoyu Lv, Qinglei Zhang, Yongming Deng, Chuan Zhang, Rui Luo, Xiaozhi Zhao, Wei Wang, Feng Wang, Hongqian Guo
BACKGROUND: To evaluate the diagnostic value of (68)Ga-PSMA-11 PET-CT with multiparametric magnetic resonance imaging (mpMRI) for lymph node (LN) staging in patients with intermediate- to high-risk prostate cancer (PCa) undergoing radical prostatectomy (RP) with pelvic lymph node dissection (PLND). METHODS: We retrospectively identified 42 consecutive patients with intermediate- to high-risk PCa according to D'Amico and without concomitant cancer. Preoperative (68)Ga-PSMA-11 PET-CT, pelvic mpMRI and subsequent robot assisted laparoscopic RP with PLND were performed in all patients...
November 7, 2017: Journal of Translational Medicine
Luigi Nocera, Akshay Sood, Deepansh Dalela, Philipp Gild, Craig G Rogers, James O Peabody, Francesco Montorsi, Mani Menon, Alberto Briganti, Firas Abdollah
PURPOSE: To evaluate the utilization of pelvic lymph node dissection (PLND) and its extent in contemporary US patients, and to correlate it to the detection of pN1 disease. PATIENTS AND METHODS: A total of 328,710 individuals who received radical prostatectomy between the years 2004 and 2013 were identified within the National Cancer Data Base. The Cochran-Armitage test was used to assess the statistical significance of temporal trends. Logistic regression analysis tested the relationship between the number of lymph nodes removed (LNR) and pN1 rate...
October 16, 2017: Clinical Genitourinary Cancer
Hye Jin Kim, Jun Seok Park, Gyu-Seog Choi, Soo Yeun Park, Hee Jae Lee
No abstract text is available yet for this article.
December 2017: Diseases of the Colon and Rectum
Annah Vollstedt, Elias Hyams
Pelvic lymph node dissection (PLND) at the time of radical prostatectomy is the most accurate method of lymph node staging in prostate cancer. Although there are varied practices in anatomic extent of PLND, evidence favors an extended PLND (ePLND) including external iliac, obdurator, and internal iliac nodes. Removing presacral and/or common iliac nodes to the ureteric crossing can improve staging. The oncologic benefits of extended dissection are unclear based on methodologic limitations and bias in the available evidence...
November 2017: Urologic Clinics of North America
Jessica G Zarzour, Sam Galgano, Jonathan McConathy, John V Thomas, Soroush Rais-Bahrami
Accurate nodal staging at the time of diagnosis of prostate cancer is crucial in determining a treatment plan for the patient. Pelvic lymph node dissection is the most reliable method, but is less than perfect and has increased morbidity. Cross sectional imaging with computed tomography (CT) and magnetic resonance imaging (MRI) are non-invasive tools that rely on morphologic characteristics such as shape and size of the lymph nodes. However, lymph nodes harboring metastatic disease may be normal sized and non-metastatic lymph nodes may be enlarged due to reactive hyperplasia...
October 28, 2017: World Journal of Radiology
D Verver, M F Madu, C M C Oude Ophuis, M Faut, J H W de Wilt, J J Bonenkamp, D J Grünhagen, A C J van Akkooi, C Verhoef, B L van Leeuwen
BACKGROUND: The optimal extent of groin completion lymph node dissection (CLND) (inguinal or ilioinguinal dissection) in patients with melanoma is controversial. The aim of this study was to evaluate whether the extent of groin CLND after a positive sentinel node biopsy (SNB) is associated with improved outcome. METHODS: Data from all sentinel node-positive patients who underwent groin CLND at four tertiary melanoma referral centres were retrieved retrospectively...
November 2, 2017: British Journal of Surgery
Teppei Matsumoto, Shingo Hatakeyama, Teppei Ookubo, Koji Mitsuzuka, Shintaro Narita, Takamitsu Inoue, Shinichi Yamashita, Takuma Narita, Takuya Koie, Sadafumi Kawamura, Tatsuo Tochigi, Norihiko Tsuchiya, Tomonori Habuchi, Yoichi Arai, Chikara Ohyama
The aim of the present study was to assess the cost-effectiveness of extended pelvic lymph node dissection (ePLND) compared to neoadjuvant chemohormonal therapy using gonadotropin-releasing hormone agonist/antagonist and estramustine. We retrospectively analyzed data within Michinoku Urological Cancer Study Group database containing 2971 PC patients treated with radical prostatectomy (RP) at four institutes between July 1996 and July 2017. We identified 237 and 403 high-risk patients who underwent RP and ePLND (ePLND group), and neoadjuvant chemohormonal therapy followed by RP and limited PLND (neoadjuvant group), respectively...
October 31, 2017: Medical Oncology
Marie Schaub, Lise Lecointre, Emilie Faller, Thomas Boisramé, Arnaud Wattiez, Jean-Jacques Baldauf, Cherif Akladios
STUDY OBJECTIVE: Describe the surgical technique of laparoscopic retroperitoneal lumboaortic lymphadenectomy using vessel-sealing device in 10 steps DESIGN: Educative video (Canadian Task Force Classification III) SETTING: Tertiary referral center in Strasbourg, France. The local institutional review board approved the video. BACKGROUND: Lumboaortic lymphadenectomy is frequently performed in the surgical management of different gynaecologic pelvic malignancies: cervical endometrial and ovarian cancer...
October 24, 2017: Journal of Minimally Invasive Gynecology
Hiroshi Tamura, Yoshifumi Shimada, Hitoshi Kameyama, Ryoma Yagi, Yosuke Tajima, Takuma Okamura, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Jun Sakata, Takashi Kobayashi, Shin-Ichi Kosugi, Hitoshi Nogami, Satoshi Maruyama, Yasumasa Takii, Toshifumi Wakai
AIM: To assess the clinical significance of prophylactic lateral pelvic lymph node dissection (LPLND) in stage IV low rectal cancer. METHODS: We selected 71 consecutive stage IV low rectal cancer patients who underwent primary tumor resection, and enrolled 50 of these 71 patients without clinical LPLN metastasis. The patients had distant metastasis such as liver, lung, peritoneum, and paraaortic LN. Clinical LPLN metastasis was defined as LN with a maximum diameter of 10 mm or more on preoperative pelvic computed tomography scan...
October 10, 2017: World Journal of Clinical Oncology
Veerle H Groen, Tycho M T W T Lock, Bart de Keizer, Simon Horenblas, Richard P Meijer
We report a case of a 65-year-old patient with muscle invasive bladder cancer that was treated with neoadjuvant chemotherapy, followed by radical cystoprostatectomy with pelvic lymph node dissection and orthotopic neobladder according to Hautmann. Nine years later, routine follow-up showed local recurrence in the neobladder and metastatic disease of the urothelial carcinoma in the related mesenteric lymph nodes. The entire neobladder specimen was removed including the mesentery of the neobladder. Based on the anatomical lymph drainage of the ileal neobladder, we considered the metastatic disease in the mesentery lymph node as locoregional disease spread...
October 24, 2017: BMJ Case Reports
Giorgio Gandaglia, Emanuele Zaffuto, Nicola Fossati, Marco Bandini, Nazareno Suardi, Elio Mazzone, Paolo Dell'Oglio, Armando Stabile, Massimo Freschi, Francesco Montorsi, Alberto Briganti
OBJECTIVES: To assess if the preoperative lymph node invasion (LNI) risk could be used to tailor the extent of pelvic lymph node dissection (PLND) according to individual profile in prostate cancer (PCa) patients undergoing radical prostatectomy (RP) and to identify those who would benefit from the removal of the common iliac and presacral nodes. PATIENTS AND METHODS: 471 high-risk PCa patients treated with RP and a super-extended PLND that included the removal of the pre-sacral and common iliac nodes between 2006 and 2016 were identified...
October 24, 2017: BJU International
Menghan Zhu, Nan Jia, Feifei Huang, Xiaoxia Liu, Yuqing Zhao, Xiang Tao, Wei Jiang, Qin Li, Weiwei Feng
BACKGROUND: Our research aimed to investigate whether lymphadenectomy was required in patients with intermediate-risk endometrioid endometrial cancer (EEC). METHODS: Between 1989 and 2015, 1009 patients with intermediate-risk EEC: grade 1 or 2 tumor, <50% myometrial invasion, and a tumor diameter ≥ 2 cm and 818 low-risk patients with grade 1 or 2 tumor, <50% myometrial invasion, and a tumor diameter < 2 cm were enrolled in this study. The rate and risk factors of node metastasis were evaluated and compared between the two risk groups...
October 23, 2017: BMC Cancer
L Ma, K Nakamae, J Wang, H Kiyomatsu, H Tsukihara, E Kobayashi, I Sakuma
Laparoscopic pelvic lymph node dissection is a delicate operation because pelvic arteries, which should be located first to guide the dissection, are often concealed by tissues and cannot be identified in the endoscopic view. Consequently, arteries can be damaged if they are not located accurately. To improve dissection safety and efficiency, we have developed an image-guided navigation system to provide pelvic artery position information by registering a 3D artery model extracted from CT images to a 3D model reconstructed from free-hand laparoscopic ultrasound images...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
Glauco Baiocchi, Henrique Mantoan, Lillian Yuri Kumagai, Bruna Tirapelli Gonçalves, Levon Badiglian-Filho, Ademir Narciso de Oliveira Menezes, Carlos Chaves Faloppa, Louise De Brot, Alexandre Andre Balieiro Anastacio da Costa
BACKGROUND: This study aimed to determine the impact of sentinel lymph node (SLN)-mapping on the staging of high-risk endometrial cancer (endometrioid grade 3, serous, clear cell, carcinosarcoma, deep myometrial invasion, or angiolymphatic invasion). METHODS: The study analyzed a series of 236 patients treated at AC Camargo Cancer Center from June 2007 to February 2017. The compared 75 patients who underwent SLN-mapping (SLN group) with 161 patients who received pelvic ± para-aortic lymphadenectomy (N-SLN group)...
October 20, 2017: Annals of Surgical Oncology
Oguzhan Kuru, Gokhan Boyraz, Hasan Uckan, Anıl Erturk, Murat Gultekin, Nejat Ozgul, Coskun Salman, Kunter Yuce
OBJECTIVE: To investigate the incidence of retroperitoneal lymph node metastasis among patients with primary adult type granulosa cell tumor (AGCT) of the ovary. STUDY DESIGN: Between January 1982 and February 2017, patients with a pathological diagnosis of AGCT were identified. Clinical and pathological data were obtained from database records. RESULTS: A total of 151 patients with primary AGCT were identified with a mean age of 47.8 years (range, 17-91 years)...
October 9, 2017: European Journal of Obstetrics, Gynecology, and Reproductive Biology
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