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Pelvic lymph node dissection

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https://www.readbyqxmd.com/read/29777008/multispectral-fluorescence-imaging-as-a-tool-to-separate-healthy-and-disease-related-lymphatic-anatomies-during-robot-assisted-laparoscopic-procedures
#1
Philippa Meershoek, Gijs H KleinJan, Matthias N van Oosterom, Esther M Wit, Danny M van Willigen, Kevin P Bauwens, Erik J van Gennep, Alexandre M Mottrie, Henk G van der Poel, Fijs van Leeuwen
To reduce the invasive nature of extended pelvic lymph node dissections (ePLND) in prostate cancer, we have developed a multicolor fluorescence guidance approach that enables the discrimination between prostate draining lymph nodes (LNs) and lower limb draining LNs. Methods: In five porcine models multispectral-fluorescence guidance was performed using da Vinci Si- and Xi-robot consoles. They received fluorescein into the lower limb(s) and indocyanine green (ICG)-nanocolloid into the prostate. Results: Fluorescein was detected in 29 LNs (average of 3...
May 18, 2018: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/29775698/prospective-randomized-controlled-trial-exploring-the-effect-of-tachosil%C3%A2-on-lymphocele-formation-after-extended-pelvic-lymph-node-dissection-in-prostate-cancer
#2
Sarah Buelens, Charles Van Praet, Filip Poelaert, Andries Van Huele, Karel Decaestecker, Nicolaas Lumen
OBJECTIVES: To explore whether TachoSil®, a hemostatic patch, can reduce the incidence of lymphocele formation. Development of a lymphocele is a frequent complication after pelvic lymph node dissection (PLND) for nodal staging in prostate cancer. MATERIALS AND METHODS: From 2013 - 2017, 100 patients with prostate cancer who were set to undergo a staging PLND before external beam radiotherapy (n = 50) or PLND concomitant with radical prostatectomy (RP) (n = 50) were prospectively randomized 1:1 between bilateral TachoSil® placement or not...
May 15, 2018: Urology
https://www.readbyqxmd.com/read/29774757/extended-pelvic-lymph-node-dissection-in-bladder-cancer
#3
Roger Li, Firas G Petros, John W Davis
INTRODUCTION: Radical cystectomy and extended pelvic lymph node dissection (ePLND) are the gold standard treatment for muscle-invasive bladder cancer and BCG unresponsive nonmuscle-invasive bladder cancer. In this article, we review the rationale for ePLND in the treatment of bladder cancer and the evidence supporting the equipoise between robot-assisted (RA) and open ePLND. A step-by-step guide of robot-assisted ePLND (RA ePLND) is provided to illustrate the techniques currently employed at our institution...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29773071/endometrial-cancer-how-many-patients-could-benefit-from-sentinel-lymph-node-dissection
#4
Sarah Brugger, Moritz Hamann, Marc Mosner, Michaela Beer, Michael Braun, Martin Pölcher
BACKGROUND: Sentinel lymph node dissection (SLND) may reduce morbidity in patients with endometrial cancer. The objective of this study is to estimate how many systematic lymph node dissections (LND) can be spared with an implementation of a SLN-procedure. METHODS: Retrospective, single-center study, SLND according to NCCN-Guidelines. RESULTS: In 109 patients of 154 consecutive patients, SLND was performed. The detection rate was 61% on both sides and 86% on at least one side...
May 17, 2018: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29770621/are-patients-and-physicians-willing-to-accept-less-radical-procedures-for-cervical-cancer
#5
Kemal Gungorduk, Roman Kocian, Derman Basaran, Taner Turan, Aykut Ozdemir, David Cibula
OBJECTIVE: To evaluate the opinions of women who underwent surgery for cervical cancer (CC) and physicians who treat CC about the acceptability of increased oncological risk after less-radical surgery. METHODS: One hundred eighty-two women who underwent surgery for CC and 101 physicians participated in a structured survey in 3 tertiary cancer centers in Czech Republic and Turkey. Patients and physicians were asked whether they would accept any additional oncological risks, which would be attributable to the omission of parametrectomy (radical hysterectomy/trachelectomy vs...
March 12, 2018: Journal of Gynecologic Oncology
https://www.readbyqxmd.com/read/29767326/fluorescence-supported-lymphography-and-extended-pelvic-lymph-node-dissection-in-robot-assisted-radical-prostatectomy-a-prospective-randomized-trial
#6
Nina Natascha Harke, Michael Godes, Christian Wagner, Mustapha Addali, Bernhard Fangmeyer, Katarina Urbanova, Boris Hadaschik, Jorn H Witt
PURPOSE: To demonstrate the benefits of fluorescence-supported extended pelvic lymph node dissection (ePLND) compared to regular ePLND in robot-assisted radical prostatectomy. METHODS: 120 patients with intermediate- or high-risk prostate cancer were prospectively randomized (1:1): in the intervention group, indocyanine green (ICG) was injected transrectally into the prostate before docking of the robot. In both groups, ePLND was performed including additional dissection of fluorescent lymph nodes (LN) in the ICG group...
May 16, 2018: World Journal of Urology
https://www.readbyqxmd.com/read/29743950/multimodality-management-of-leiomyosarcoma-of-the-cervix
#7
Vijaya Kumar Jayaram, J Parikshith, Geeta Sowmya Narayanan, Richa Tiwari, R Veena, S Prathima, M S Ganesh, Chattakonda Sai Snehith, Esther Praisy
We present the case of a young female patient who presented to the outpatient department with a history of bleeding per vagina, diagnosed with leiomyosarcoma of the cervix; the patient underwent total abdominal hysterectomy with pelvic lymph node dissection. In this article, we mainly discuss multimodality therapy in the management of an unusual variety of tumour in the uterine cervix.
2018: Ecancermedicalscience
https://www.readbyqxmd.com/read/29742860/essential-anatomy-of-the-anorectum-for-colorectal-surgeons-focused-on-the-gross-anatomy-and-histologic-findings
#8
REVIEW
Jong Min Lee, Nam Kyu Kim
The anorectum is a region with a very complex structure, and surgery for benign or malignant disease of the anorectum is impossible without accurate anatomical knowledge. The conjoined longitudinal muscle consists of smooth muscle from the longitudinal muscle of the rectum and the striate muscle from the levator ani and helps maintain continence; the rectourethralis muscle is connected directly to the conjoined longitudinal muscle at the top of the external anal sphincter. Preserving the rectourethralis muscle without damage to the carvernous nerve or veins passing through it when the abdominoperineal resection is implemented is important...
April 2018: Annals of Coloproctology
https://www.readbyqxmd.com/read/29741977/laparoscopic-pelvic-exenteration-for-locally-advanced-rectal-cancer-technique-and-short-term-outcomes
#9
Ashish Pokharkar, Praveen Kammar, Ashwin D'souza, Rahul Bhamre, Pavan Sugoor, Avanish Saklani
BACKGROUND: Since last two decades minimally invasive techniques have revolutionized surgical field. In 2003 Pomel first described laparoscopic pelvic exenteration, since then very few reports have described minimally invasive approaches for total pelvic exenteration. METHODS: We report the 10 cases of locally advanced rectal adenocarcinoma which were operated between the periods from March 1, 2017 to November 11, 2017 at the Tata Memorial Hospital, Mumbai. All male patients had lower rectal cancer with prostate involvement on magnetic resonance imaging (MRI)...
May 9, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29738162/-radical-retropubic-prostatectomy-for-prostate-cancer-with-pelvic-lymph-node-metastasis
#10
Ding-Yi Liu, Sang Hu, Yan-Feng Zhou, Hong-Chao He, Jia-Shun Yu, Jian Wang, Wei-Mu Xia, Qi Tang, Ming-Wei Wang, Wen-Long Zhou
Objective: To investigate the safety and effectiveness of radical retropubic prostatectomy (RRP) with adjuvant androgen deprivation or external radiotherapy in the treatment of prostate cancer (PCa) with pelvic lymph node metastasis (PLNM). METHODS: Twenty PCa patients underwent bilateral pedal lymphangiography (PLG) preoperatively, and 11 of them received lymph node aspiration for examination of the mRNA expressions of prostate-specific antigen (PSA) and prostate-specific membrane antigen (PSMA) in the lymph fluid by real-time RT-PCR...
November 2017: Zhonghua Nan Ke Xue, National Journal of Andrology
https://www.readbyqxmd.com/read/29737495/body-mass-index-is-an-independent-predictor-of-clavien-dindo-grade-3-complications-in-patients-undergoing-robot-assisted-radical-prostatectomy-with-extensive-pelvic-lymph-node-dissection
#11
Antonio Benito Porcaro, Marco Sebben, Alessandro Tafuri, Nicolò de Luyk, Paolo Corsi, Tania Processali, Marco Pirozzi, Riccardo Rizzetto, Nelia Amigoni, Daniele Mattevi, Maria A Cerruto, Matteo Brunelli, Giovanni Novella, Vincenzo De Marco, Filippo Migliorini, Walter Artibani
Robot assisted radical prostatectomy (RARP) with extensive pelvic lymph node dissection (ePLND) is an effective procedure for treating and staging prostate cancer; however, high grade complications represent a critical issue. To investigate clinical factors associated with the risk of Clavien-Dindo grade 3 complications in patients undergoing RARP with ePLND. The study included 211 consecutive patients who were operated in a period running from June 2013 to March 2017. Factors associated with grade 3 complications were evaluated by the logistic regression model...
May 8, 2018: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/29734878/pelvic-lymph-node-dissection-in-prostate-cancer-staging-evaluation-of-morbidity-and-oncological-outcomes
#12
Andries Van Huele, Filip Poelaert, Valérie Fonteyne, Karel Decaestecker, Piet Ost, Nicolaas Lumen
BACKGROUND: To evaluate the morbidity of different surgical approaches for pelvic lymph node dissection (PLND), to evaluate the influence of morbidity on radiotherapy (RT) planning and to evaluate a possible therapeutic effect of a more extensive yield of PLND. METHODS: From 2000-2016, 228 patients received staging PLND before primary RT in a single tertiary care center. Nine patients were excluded for the evaluation of morbidity. Fifty patients were operated in an open approach, 96 laparoscopic and 73 robot-assisted (RA)...
May 8, 2018: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/29732201/robot-assisted-radical-cystectomy-first-polish-clinical-outcomes
#13
Przemysław Adamczyk, Kajetan Juszczak, Pawel Poblocki, Witold Mikolajczak, Tomasz Drewa
Introduction: Urothelial cell carcinoma is the most common neoplasm of the genito-urinary tract, which, in advanced stages, is treated with radical cystectomy with pelvic lymphadenectomy. It can be performed by an open or minimally invasive approach (laparoscopic and robot-assisted radical cystectomy).Large meta-analyses showed a significantly lower complication rate in the RARC (robot-assisted radical cystectomy) group compared to ORC (open radical cystectomy) in thirty and ninety days after surgery, with similar oncological and functional outcomes...
2018: Central European Journal of Urology
https://www.readbyqxmd.com/read/29731507/primary-papillary-serous-carcinoma-of-the-fallopian-tube-presenting-as-a-vaginal-mass-a-case-report-and-review-of-the-literature
#14
Einav Kadour-Peero, Lena Sagi-Dain, Gil Cohen, Roman Korobochka, Abed Agbarya, Jacob Bejar, Shlomi Sagi
BACKGROUND There is now evidence to support that some cases of high-grade serous papillary carcinoma arise from the fallopian tubes rather than the ovaries. Common symptoms at presentation include abdominal pain and swelling, vomiting, altered bowel habit and urinary symptoms. To our knowledge, this is the first case of serous papillary carcinoma presenting as a vaginal mass lesion. CASE REPORT A 41-year-old woman was referred to the Bnai-Zion Medical Center with the main complaint of irregular vaginal bleeding, vaginal mucous discharge, and suspected pelvic mass...
May 7, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29727352/role-of-extensive-lymphadenectomy-in-early-stage-cervical-cancer-patients-with-radical-hysterectomy-followed-by-adjuvant-radiotherapy
#15
Natsuo Tomita, Mika Mizuno, Shinji Kondo, Masahiko Mori, Sho Takeshita, Jun Sakata, Hirofumi Tsubouchi, Takeshi Kodaira
OBJECTIVES: The objective of this study was to assess the effect of extensive lymphadenectomy on survival of early-stage cervical cancer patients with radical hysterectomy followed by adjuvant radiotherapy (RT). MATERIALS AND METHODS: A retrospective analysis was performed on early-stage patients with high-risk factors who received radical hysterectomy with lymphadenectomy followed by adjuvant RT. All patients were divided into the less than or equal to 40 dissected pelvic lymph nodes (DPLN ≤40) and greater than 40 dissected pelvic lymph nodes (DPLN >40) groups to assess the effect of extensive lymphadenectomy...
April 30, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29727351/comparison-of-different-surgical-approaches-for-stage-ib1-cervical-cancer-patients-a-multi-institution-study-and-a-review-of-the-literature
#16
Giacomo Corrado, Enrico Vizza, Francesco Legge, Luigi Pedone Anchora, Isabella Sperduti, Anna Fagotti, Emanuela Mancini, Valerio Gallotta, Ashanti Zampa, Benito Chiofalo, Giovanni Scambia
OBJECTIVE: The aim of this retrospective study was to assess the surgical and oncological outcome of 3 different surgical approaches (laparotomy, laparoscopy, and robotic surgery) in the treatment of early-stage cervical cancer International Federation of Gynecology and Obstetrics (FIGO) stage IB1. METHODS: All patients with a histologically confirmed diagnosis of early-stage cervical cancer, FIGO stage IB1, who underwent abdominal radical hysterectomy (ARH), laparoscopic radical hysterectomy, or robotic radical hysterectomy with or without pelvic and aortic lymphadenectomy were included in the study...
April 30, 2018: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/29721748/oncological-outcomes-of-robotic-assisted-laparoscopic-versus-open-lateral-lymph-node-dissection-for-locally-advanced-low-rectal-cancer
#17
Tomohiro Yamaguchi, Yusuke Kinugasa, Akio Shiomi, Hiroyasu Kagawa, Yushi Yamakawa, Akinobu Furutani, Shoichi Manabe, Yusuke Yamaoka, Hitoshi Hino
BACKGROUND: The long-term outcomes of robotic-assisted laparoscopic lateral lymph node dissection (RALLD) have not been fully investigated. This study aimed to assess the oncological and long-term outcomes of RALLD for rectal cancer through comparison with those of open lateral lymph node dissection (OLLD) in a retrospective study. METHODS: Between September 2002 and October 2014, the medical data of 426 patients who underwent total mesorectal excision with lateral lymph node dissection for primary rectal cancer were collected...
May 2, 2018: Surgical Endoscopy
https://www.readbyqxmd.com/read/29720348/impact-of-adjuvant-radiotherapy-in-node-positive-prostate-cancer-patients-the-importance-of-patient-selection
#18
Firas Abdollah, Deepansh Dalela, Akshay Sood, Jacob Keeley, Shaheen Alanee, Alberto Briganti, Francesco Montorsi, James O Peabody, Mani Menon
Using institutional data, we have previously developed an algorithm to identify the optimal candidates for adjuvant radiotherapy (aRT) among men with pN1 prostate cancer (PCa) at radical prostatectomy (RP). This study aimed to test the external validity of our previous findings using a nationwide database while focusing on overall mortality as an endpoint. To this end, we identified 5498 pN1 PCa patients who were treated with RP, pelvic lymph node dissection, and androgen deprivation therapy with or without aRT, within the National Cancer Database, between 2004 and 2015...
April 29, 2018: European Urology
https://www.readbyqxmd.com/read/29714659/prostate-specific-antigen-associates-with-extensive-lymph-node-invasion-in-high-risk-prostate-cancer
#19
Antonio B Porcaro, Paolo Corsi, Davide Inverardi, Marco Sebben, Alessandro Tafuri, Tania Processali, Daniele Mattevi, Davide De Marchi, Marco Pirozzi, Maria A Cerruto, Nelia Amigoni, Riccardo Rizzetto, Matteo Brunelli, Salvatore Siracusano, Walter Artibani
OBJECTIVE: To evaluate clinical predictors of lymph node invasion (LNI) in patients with high-risk prostate cancer undergoing radical prostatectomy (RP) with extended pelvic lymph node dissection (ePLND). METHODS: A contemporary cohort of 116 patients, who underwent ePLND during RP, was retrospectively evaluated. Patients were classified into 3 groups including cases without LNI (group 1), with 1 to 3 positive nodes (group 2; limited LNI), and with more than 3 positive nodes (group 3; extensive LNI)...
April 1, 2018: Tumori
https://www.readbyqxmd.com/read/29704059/contemporary-rates-of-adherence-to-international-guidelines-for-pelvic-lymph-node-dissection-in-radical-cystectomy-a-population-based-study
#20
Emanuele Zaffuto, Marco Bandini, Stéphanie Gazdovich, Anne-Sophie Valiquette, Sami-Ramzi Leyh-Bannurah, Zhe Tian, Paolo Dell'Oglio, Markus Graefen, Marco Moschini, Andrea Necchi, Shahrokh F Shariat, Alberto Briganti, Francesco Montorsi, Pierre I Karakiewicz
OBJECTIVE: To examine the rates of adherence to guidelines for pelvic lymph node dissection (PLND) in patients treated with radical cystectomy (RC) and to identify predictors of omitting PLND. MATERIALS AND METHODS: We relied on 66,208 patients treated with RC between 2004 and 2013 within the National Inpatients Sample (NIS) database. We examined the rates of PLND according to year of surgery, patient and hospital characteristics. Univariate and multivariate logistic regression analyses assessed the probability of PLND use, after adjusting for year of surgery, age, gender, race, comorbidities, hospital location, teaching status and hospital surgical volume...
April 27, 2018: World Journal of Urology
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