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Gaetano Poillucci, Lorenzo Mortola, Mauro Podda, Salomone Di Saverio, Laura Casula, Chiara Gerardi, Nicola Cillara, Luigi Presenti
Acute appendicitis (AA) is among the most common causes of acute lower abdominal pain leading patients to the emergency department. Significant debate remains on whether AA should be operated or not. A propensity score-matched analysis was performed in seven Italian Hospitals, with the aim to assess safety and feasibility both nonoperative management with antibiotics (AT) and surgical therapy with appendectomy (ST) for patients with AA. Data regarding all patients discharged from the participating centers with a diagnosis of appendicitis from January 1st, 2014 to December 31st, 2014 were collected retrospectively...
December 2017: Updates in Surgery
Mauro Rodrigues Dos Santos, Junichiro Sado, Roberto Medeiros de Sousa, Osman Rodrigues Roriz
OBJECTIVE: To evaluate the intra-observer reproducibility of Schatzker classification for tibial plateau fractures through smartphone applications. METHODS: Radiographs were evaluated in two incidences (anteroposterior and profile) and CT slices (axial, sagittal and coronal) of 37 patients with tibial plateau fracture. Two evaluators, knee surgery experts, classified the cases by viewing the images of the isolated radiographs and then X-rays associated with CT slices in four different stages via smartphones and then presential assessment...
November 2016: Acta Ortopedica Brasileira
Ilaria Sabatucci, Domenica Lorusso
Riassunto. I PARP inibitori interferiscono con la riparazione del danno nella singola elica del DNA determinando una progressione del difetto nella doppia elica. In circa il 50% delle pazienti con carcinoma dell'ovaio sieroso di alto grado sono presenti difetti nei meccanismi di ricombinazione omologa, deputati alla riparazione del danno della doppia elica del DNA. L'incapacità di riparare il danno si traduce nella morte cellulare, un processo definito "letalità sintetica". Nella famiglia dei PARP inibitori il niraparib è stato il primo a essere approvato dalla FDA nel trattamento delle pazienti con carcinoma ovarico ricorrente indipendentemente dalla presenza o assenza di mutazioni BRCA...
June 2017: Recenti Progressi in Medicina
Eleni Rebelos, Alessandro Cipriano, Alessio Maffei, Gaetano Diricatti, Massimo Santini
INTRODUCTION: In the Medline database there are approximately 60 cases reporting toxic pulmonary edema, a life-threatening event, induced after consumption of hydrochlorothiazide, one of the most common antihypertensive drugs. Moreover, increased procalcitonin concentrations have been reported after cardiogenic pulmonary edema. We report the rare case of a hydrochlorothiazide-induced pulmonary edema, which was followed by a marked increase of the procalcitonin concentrations. CLINICAL CASE: A middle-aged woman was admitted to the Emergency Department for severe dyspnea and chills...
April 2017: Recenti Progressi in Medicina
Mauro Esposito, Stefania Cavallo, Guido Rosato, Eugenio Chiaravalle, Oto Miedico, Roberta Pellicanò, Vittorio Soprano, Loredana Baldi
INTRODUZIONE: una vasta area compresa tra le province di Napoli e Caserta nella regione Campania ha negli ultimi anni attirato l'attenzione dei mass media a causa degli interramenti illeciti di rifiuti di varia origine nei campi o del loro abbandono lungo le strade. A tali pratiche illecite si aggiunge il fenomeno dei roghi incontrollati di questo materiale, motivo per il quale la zona è stata soprannominata "Terra dei fuochi". OBIETTIVI: ricerca di elementi in tracce presenti nei prodotti alimentari di origine vegetale prodotti nella Terra dei fuochi...
September 2016: Epidemiologia e Prevenzione
Elisa Bustaffa, Annamaria De Marinis Loiotile, Genoveffa Farella, Stefania Petraccone, Gianluigi De Gennaro, Fabrizio Bianchi
La continua espansione delle attività di perforazione ai fini dell'estrazione petrolifera in prossimità di aree abitate ha fatto sì che negli ultimi anni l'attenzione si focalizzasse sull'impatto di questo processo fortemente industrializzato sulla salute pubblica. Le comunità che vivono nei dintorni di impianti di questo tipo devono, infatti, fronteggiare diversi problemi, quali l'inquinamento atmosferico e acustico, la contaminazione del suolo e delle acque sotterranee, il traffico dei camion da e verso il sito, incidenti e malfunzionamenti all'interno dell'impianto...
September 2016: Epidemiologia e Prevenzione
Diana Lewis, Heather Castleden, Sheila Francis, Kim Strickland, Colleen Denny
BACKGROUND: Designing an effective survey for gathering primary health data using a community-based participatory research (CBPR) approach in Indigenous communities in Canada has its challenges. Yet, the Pictou Landing First Nation (PFLN) Native Women's Group (NWG) and academic research partners achieved a 59% response rate. OBJECTIVES: To share lessons learned with both campus and community-based research teams engaged in CBPR involving Indigenous communities on the process of team development, and particularly survey development and execution, as well as the factors that led to a reliable and valid household level environmental health survey that achieved a 59% response rate...
2016: Progress in Community Health Partnerships: Research, Education, and Action
Karthikeyan Thiyagarajan, Fabio Vitali, Valentina Tolaini, Patrizia Galeffi, Cristina Cantale, Prashant Vikram, Sukhwinder Singh, Patrizia De Rossi, Chiara Nobili, Silvia Procacci, Antonella Del Fiore, Alessandro Antonini, Ombretta Presenti, Andrea Brunori
Phenylalanine Ammonia Lyase (PAL) gene which plays a key role in bio-synthesis of medicinally important compounds, Rutin/quercetin was sequence characterized for its efficient genomics application. These compounds possessing anti-diabetic and anti-cancer properties and are predominantly produced by Fagopyrum spp. In the present study, PAL gene was sequenced from three Fagopyrum spp. (F. tataricum, F. esculentum and F. dibotrys) and showed the presence of three SNPs and four insertion/deletions at intra and inter specific level...
2016: PloS One
Daryl Bem, Patrizio Tressoldi, Thomas Rabeyron, Michael Duggan
In 2011, one of the authors (DJB) published a report of nine experiments in the Journal of Personality and Social Psychology purporting to demonstrate that an individual's cognitive and affective responses can be influenced by randomly selected stimulus events that do not occur until after his or her responses have already been made and recorded, a generalized variant of the phenomenon traditionally denoted by the term precognition. To encourage replications, all materials needed to conduct them were made available on request...
2015: F1000Research
Alexander Siller, Wolfgang Ambach, Dieter Vaitl
The study aimed at experimentally investigating whether the human body can anticipate future events under improved methodological conditions. Previous studies have reported contradictory results for the phenomenon typically called presentiment. If the positive findings are accurate, they call into doubt our views about human perception, and if they are inaccurate, a plausible conventional explanation might be based on the experimental design of the previous studies, in which expectation due to item sequences was misinterpreted as presentiment...
2015: Frontiers in Psychology
Isabel Cuadrado-Gordillo, Inmaculada Fernández-Antelo
The co-occurrence of bullying and cyberbullying in a dual society like the present calls for specific measures of intervention to be able to forestall the emergence of new problems and slow the increase and diversification of violent behavior. This study's objective was to determine whether the gender of those involved as well as the forms of aggression experienced both in presential and virtual scenarios are predictive indicators of the violent behavior of aggressive-victims. The participant sample was 1,648 adolescents aged 12 to 16 years (48...
January 2016: Journal of Interpersonal Violence
O Martín Gordo, V Martín Moreno, D Agüero Orgaz, A Martín Fernández, E R Coaquira Condori, S Duce Tello
OBJECTIVE: Chronic disease is the main epidemic of the 21st century. It takes up a large part of the social-health budgets that are dedicated to its care. The aim of this study is to analyze if the welfare quality in the management of the chronic patients improves by implementing non-contact care time. MATERIAL AND METHODS: Intervention study conducted in the health care center of Orcasitas (January 2012 - September 2013) in patients with hypertension (357), diabetes (180) and/or ischemic heart disease (60)...
September 2014: Revista de Calidad Asistencial: Organo de la Sociedad Española de Calidad Asistencial
Ernesto Bonilla
Every day new scientific information is appearing that cannot be explained using the classical Newtonian model and is calling for the emergence of a new paradigm that would include the explanation of such phenomena as telepathy, clairvoyance, presentiment, precognition, out of the body experiences, psychic healing, after-death communication, near-death experiences and reincarnation. The materialist paradigm which considers the brain as the sole cause of consciousness and psychic phenomena has been challenged by a new paradigm that seems to demonstrate that there is not a cause-effect relationship between brain activity and psychic phenomena but only a correlation between them, since these phenomena can be experienced without the body and appear to have an extra-cerebral origin (cosmic field, cosmic consciousness?)...
June 2014: Investigación Clínica
Rosa Madridejos Mora, Lourdes Majem Fabres, Helena Puig Acebal, Inma Sanz Latorre, Eva Llobet Traveset, Mar Arce Casas, Dolors Ruiz Morilla, Angel Mercadal Dalmau, Dani Pañart Sánchez
OBJECTIVE: To improve the knowledge of the population about heart-healthy habits through a training program supplemented by a web site and community activities. DESIGN: A controlled clinical trial with intervention done through participation in the Cardiovascular Health Training Classroom (CHTC) LOCATION: A town of 80,000 inhabitants. PARTICIPANTS: HASH(0x331c7f0) PATIENTS: both sexes, aged 55 to 70 years, with at least one cardiovascular risk factor (CVRF)...
November 2014: Atencion Primaria
Julia A Mossbridge, Patrizio Tressoldi, Jessica Utts, John A Ives, Dean Radin, Wayne B Jonas
A recent meta-analysis of experiments from seven independent laboratories (n = 26) indicates that the human body can apparently detect randomly delivered stimuli occurring 1-10 s in the future (Mossbridge etal., 2012). The key observation in these studies is that human physiology appears to be able to distinguish between unpredictable dichotomous future stimuli, such as emotional vs. neutral images or sound vs. silence. This phenomenon has been called presentiment (as in "feeling the future"). In this paper we call it predictive anticipatory activity (PAA)...
2014: Frontiers in Human Neuroscience
Chun-Sheng Xu, Ping Yang, Hui-Jun Bao, Xun-Guang Bian, Qiu-Sheng Chen
The structure of the nephron in adult soft-shelled turtles (Pelodiscus sinensis) was studied by light microscopy, transmission and scanning electron microscopy. The kidney contained 5-6 renal lobes. Nephrons of P. sinensis are composed of a renal corpuscle (RC) and of a renal tubule that appears divided morphologically into five distinct segments: neck segment (NS) (This segment is only present in approximately 10% of the nephrons), proximal tubule (PT), intermediate segment (IS), distal tubule (DT), and collecting duct (CD)...
January 2013: Micron: the International Research and Review Journal for Microscopy
Eliana Louzada Petito, Afonso Celso Pinto Nazário, Simone Elias Martinelli, Gil Facina, Maria Gaby Rivero De Gutiérrez
The aim of this study was to evaluate the effectiveness of an exercise program for the recuperation of the range of motion (ROM) of the shoulder. This is a quasi-experimental study developed at the Mastology Outpatient Clinic of the Federal University of São Paulo - Brazil, from August 2006 to June 2008, with 64 breast cancer patients undergoing surgery. The intervention consisted of: preoperative evaluation of the ROM, verbal and written guidance, demonstration and implementation of the exercises and revaluation at the outpatient follow-up appointments until the 105(th) postoperative day (PO)...
January 2012: Revista Latino-americana de Enfermagem
Rosa Dalmau, Miriam Boira, Carina Aguilar, Carlos López, Dolors Rodríguez, Delicia Gentille, Domingo Bofill, Eduard Diogene, Josep M Pepió
BACKGROUND: Cardiovascular diseases(CVD), specifically ischaemic heart disease(IHD), are the main causes of death in industrialized countries. Statins are not usually prescribed in the most appropriate way. To ensure the correct prescription of these drugs, it is necessary to develop, disseminate and implement clinical practice guidelines(CPGs), and subsequently evaluate them. The main objective of this study is to evaluate the effectiveness of the implementation of consensual Lipid-lowering drugs (LLD) prescription guidelines in hospital and primary care settings, to improve the control of Low-Density Lipoprotein Cholesterol (LDL-C) levels in patients with IHD in the Terres de l'Ebre region covered by the Catalonian Health Institute...
2011: BMC Cardiovascular Disorders
Mercedes Rigla
Although current systems for continuous glucose monitoring (CGM) are the result of progressive technological improvement, and although a beneficial effect on glucose control has been demonstrated, few patients are using them. Something similar has happened to telemedicine (TM); in spite of the long-term experience, which began in the early 1980s, no TM system has been widely adopted, and presential visits are still almost the only way diabetologists and patients communicate. The hypothesis developed in this article is that neither CGM nor TM will ever be routinely implemented separately, and their consideration as essential elements for standard diabetes care will one day come from their integration as parts of a telemedical monitoring platform...
January 1, 2011: Journal of Diabetes Science and Technology
S W Hsu, G Rodesch, C B Luo, Y L Chen, H Alvarez, P L Lasjaunias
A patient with a spinal intradural arteriovenous malformation (AVM) at the conus medullaris concomitant with a sacral dural arteriovenous fistula (AVF) of the filum terminale is reported. A 44-year-old-male presentied with bilateral leg weakness and urinary incontinence for several months. Spinal angiography demonstrated two lesions: one was spinal intradural AVM at the conus medullaris supplied by the anterior spinal artery; the other was sacral dural AVF of the filum terminale supplied by the middle sacral artery...
March 30, 2002: Interventional Neuroradiology
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