Read by QxMD icon Read


Lin Yu, Jian Wang
OBJECTIVE: To investigate the clinicopathologic characteristics, differential diagnosis and biologic behaviors of pleomorphic rhabdomyosarcoma (PRMS). METHODS: The clinical findings, pathological features and immunophenotypes were reviewed in 44 cases of PRMS (encountered during the period from 2005 to 2012). The clinical outcome was analyzed. RESULTS: There were 33 males and 11 females with age ranging from 2 to 85 years (mean, 51 years; median, 55 years)...
March 2013: Zhonghua Bing Li Xue za Zhi Chinese Journal of Pathology
Samiullah, Hidayatullah, Nisar H Dar, Faisal Haque, S A Hasan
Sinus Histiocytosis with Massive Lymphadenopathy is a very rare condition often presenting as neck swelling of unknown etiology. The disease involves extranodal sites in 20-30 percent of cases and histologically characterized by emperiopolesis, non-cohesive and non-epitheloid histocytes with abundant eosinphilic cytoplasm. An ideal treatment is yet to be established but here we present a short series of chemotherapy with alternating ABVD and COPD cycles giving satisfactory results.
July 2006: Indian Journal of Otolaryngology and Head and Neck Surgery
Xin Zhang, Bo Sahlberg, Gunilla Wieslander, Christer Janson, Thorarinn Gislason, Dan Norback
There are few longitudinal studies on health effects of dampness and moulds in workplace buildings. We studied associations between dampness and indoor moulds in workplace buildings and selected biomarkers as well as incidence and remission of sick building syndrome (SBS). The study was based on a ten-year prospective study (1992-2002) in a random sample of adults (N=429) from the Uppsala part of the European Community Respiratory Health Survey (ECRHS). The 10-year incidence (onset) of general, mucosal, dermal symptoms and any symptom improved when away from the workplace (work-related symptoms) was 7...
July 15, 2012: Science of the Total Environment
A W Musk, M Knuiman, M Hunter, J Hui, L J Palmer, J Beilby, M Divitini, S Mulrennan, A James
The aim of this study was to examine how objective measures related to lung function cluster in the general population and how the patterns relate to asthma and bronchitis as diagnosed by a doctor (DDA and DDB, respectively). A cross-sectional survey of an age-stratified random general population sample of 1,969 adults from the electoral register of Busselton (Australia) was performed in 2005-2007. Respiratory symptoms, DDA ever, DDB ever, recent wheezing and smoking history, together with anthropometric measurements, forced expiratory volume in 1 s (FEV₁) and forced vital capacity (FVC), methacholine challenge or bronchodilator response, exhaled nitric oxide (eNO), skin-prick tests to common allergens, and blood eosinophil and neutrophil counts were studied...
November 2011: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
Wonyoung Kim, Juyang Kim, Changshik Shin, Hyunju Kim, Younkyung Doh, Hong R Cho, Byungsuk Kwon
Eosinophils are rare hematopietic cells that normally constitute only 1~3% of peripheral blood leukocytes. It would be of help for the purpose of research to obtain a large quantity of eosinophils. In this study, we wanted to develop a novel strategy to induce massive expansion of murine eosinophils in vivo, based on the observation showing that treatment of IL-33 induces eosinophilia in mice. We generated an EL-4 lymphoma cell line (herein named EL-4-IL-33) that was engineered to secrete an active form of IL-33...
December 15, 2010: Journal of Immunological Methods
Ji Young Ahn, Sun Eun Choi, Mi Sook Jeong, Kwan Hee Park, Nam Ju Moon, Seong Soo Joo, Chung Soo Lee, Young Wook Choi, Kapsok Li, Mi-Kyung Lee, Min Won Lee, Seong Jun Seo
Increased levels of eosinphils, IgE, IL-4, 5, and 13 and pro-inflammatory factors (COX-2, iNOS) are observed in patients with atopic dermatitis (AD). Taxifolin 3-O-beta-D-glucopyranoside (TAX) from the roots of Rhododendron mucronulatum (RM) was examined to determine whether its immunomodulatory effect was applicable for treating atopic dermatitis.A total of 7 groups of NC/Nga mice with AD were treated by topical application or intraperitoneal injection of TAX for 4 weeks. Follow-up evaluations were done to assess the changes in clinical observations, eosinophil counts, and levels of IgE, cytokines, COX-2 and iNOS...
July 2010: Phytotherapy Research: PTR
Y-H Wang, Y-J Liu
Allergic diseases are often triggered by environmental allergens that induce dominant type 2 immune responses, characterized by the infiltrated T-helper type 2 (TH2) lymphocytes, eosinophils, and elevated TH2 cytokines. In addition to TH2 type immune responses, epithelial stress and injury linked to tissue remodelling are often observed, suggesting that epithelial cells may play important role in regulating allergic responses. Dendritic cells (DCs), the professional antigen-presenting cells with the capabilities of sampling allergens, are considered as the key player on instructing TH2 immune responses...
June 2009: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
K G Lim, P F Weller
Highly purified eosinophils can be isolated from peripheral blood by negative selection using anti-CD16 immunomagnetic beads. The basic protocol describes a sequential fractionation of peripheral blood in which eosinophils are separated first from mononuclear cells and then from CD16(+) neutrophils. This technique is easy to use, fast, and highly reproducible. A support protocol describes a staining method that can be used to evaluate the purity of eosinphils.
May 2001: Current Protocols in Immunology
Ramón Carmona-Sánchez, Ernesto Sánchez-Hermosillo
No abstract text is available yet for this article.
April 2007: Revista de Gastroenterología de México
Leonardo Rossi, Ramy Moharram, Brian M Martin, Richard L White, Monica C Panelli
Monocyte Chemoattractant Proteins 4 (MCP-4/CCL13) is a member of a distinct, structurally-related subclass of CC chemokines mainly involved in recruitment of eosinphils to inflammatory sites. Recent evidence demonstrates that serum level of this protein strongly increases following high dose IL-2 immunotherapy. The physiological form of human MCP-4/CCL13 has yet to be purified. Therefore, the primary structure of the biologically relevant (mature) form has not been established. By using SELDI immunoaffinity capture technology we describe two mature isoforms both present in serum before and after high-dose IL-2 immunotherapy...
2006: Journal of Translational Medicine
No abstract text is available yet for this article.
March 1965: Sovetskaia Meditsina
Anna Wojas-Pelc, Dorota Wielowieyska-Szybińska, Sylwia Lipko-Godlewska
First time eosinophilic fasciitis (EF) was described by Shulman. It occurrences predominantly in young men, rarely older women, sporadic in children. The illness was characterised by swelling of the extremities, skin changes, myalgia, and elevation of the peripheral blood eosinophil count and hypergammaglobulinemia. It is followed by rapidly progressive cutaneous and subcutaneous induration. The histopathologic examination in the region of affected skin shows thickening of the fascia, deep dermal fibrosis and infiltration mainly consists of lymphocytes, plasmocytes, eosinphils...
2003: Przegla̧d Lekarski
H Kong, J Yang, Z Dong, Z Yang, G Pu
OBJECTIVE: To study the relation between inflammatory cells infiltration in nasal polyp tissues and it's pathogenesis. METHOD: Nasal mucosa from 10 normal individual and 4 patients of nasal polyps were studied with immunohistochemical technique and histopathologic examination. RESULT: The number of eosinophils, CD68 positive cells and monocytes was significantly higher (P < 0.05) in nasal polyps tissues than in the normal controls. CONCLUSION: Infiltration of inflammatory effector cells such as eosinphils and chronic inflammatory changes of the nasal mucosa might play a role in nasal polyps sprouting...
August 1999: Lin Chuang Er Bi Yan Hou Ke za Zhi, Journal of Clinical Otorhinolaryngology
C Prunier, C Hommet, A Autret, B de Toffol
We report the case of a 60-year-old man who developed visual and cognitive disorders. Investigations confirmed the diagnosis of idiopathic hypereosinophilic syndrome even though the patient had a history of rectal cancer. The olinical course was favorable after treatment. We discuss the different clinical forms, imaging data and treatments of eosinphilic syndrome.
October 2001: Revue Neurologique
Y I Koh, S Choi
It has been suggested that airway eosinophilic inflammation is associated with the severity of exercise-induced bronchospasm (EIB). Blood eosinophils are known to be an indirect marker of airway inflammation in asthma. The aim of this study is to investigate that a simple and easy blood test for blood eosinphil counts may predict the severity of EIB in asthma. Seventy-seven men with perennial asthma (age range 18-23 years) were included. Lung function test, skin prick test, and blood tests for eosinophils counts and total IgE levels were performed...
February 2002: Respiratory Medicine
C De Vos
H1-receptor antagonists of the first and second generation have been used for many years to relieve symptoms arising from the action of histamine on the H1 receptor. However, allergic inflammation is more than histamine release and action. Leukocyte infiltration during late allergic manifestations was demonstrated as being a hallmark of allergic inflammation. Second-generation H1-receptor antagonists were studied in models of mast cell degranulation in vitro and of leukocyte infiltration in vivo. Analysis of the literature showed that a drug which is no more metabolized than cetirizine and fexofenadine allows a better relevance of in vitro models...
July 1999: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
A R Silva, A P Larangeira, P Pacheco, J B Calixto, M G Henriques, P T Bozza, H C Castro-Faria-Neto
1. The role of both exogenously administered and endogenously generated bradykinin (BK) on LPS-induced eosinophil accumulation in the mice pleural cavity was investigated by means of treatment with BK selective receptor agonists/antagonists and captopril. 2. Intrathoracic (i.t.) injection of LPS (250 ng cavity(-1)) induced eosinophil influx at 24 h as previously described (Bozza et al., 1993). Pretreatment with the B1 receptor antagonist des-Arg9-[leu-8]BK (0.025 and 0.25 nmol cavity(-1)) showed no effect on this phenomenon, whereas pretreatment with the B2 receptor antagonists, NPC 17731 (0...
May 1999: British Journal of Pharmacology
Y Gao, Chenping, X P Lin
OBJECTIVE: In order to determine whether interferon-gamma (IFN-gamma) inhibits eosinphil infiltration in the trachea of asthmatic guinea pigs induced by Rhizopus nigricans. METHOD: We had administered aerosolized rIFN-gamma in the tracheas of 30 sensitized guinea pigs which had been divided into six groups, then teated animal inhaled rIFN-gamma of 5 x 10(4), 20 x 10(4), and 40 x 10(4) concentration, BDP and normal saline respectively at 24 h, 12 h, 2 h before being challenged...
October 1997: Chinese Journal of Tuberculosis and Respiratory Diseases
K Larsson, G Tornling, D Gavhed, C Müller-Suur, L Palmberg
Prolonged exposure to cold air may induce a chronic asthma-like condition in healthy subjects as has been demonstrated in cross-country skiers. In the present controlled study, our aim was to elucidate further the link between cold air exposure and airway inflammation by assessing the cellular influx and mediator levels within the airways following acute exposure to cold air. Bronchoalveolar (BAL) and nasal lavages were performed after exposure to cold air (-23 degrees C) and normal indoor air (+22 degrees C) during a light, intermittent work for 2 h in a cross-over design in eight healthy, nonsmoking, subjects...
October 1998: European Respiratory Journal: Official Journal of the European Society for Clinical Respiratory Physiology
S G Kayes
The surface of T. canis is now recognized as a dynamic structure which turns over quite rapidly and serves as a renewable source of large quantities of antigen(s). The major host responses to these antigens include a marked eosinophilia and hyperglobulinemia. Both of these responses are apparently ineffective at ridding the body of infective larvae. Both eosinphils and IgE antibodies are manifestations of the Th2 subset of T helper cells and the cytokines that they secrete. Further, there is reason to believe that the antigens released from T...
1997: Chemical Immunology
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"