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https://www.readbyqxmd.com/read/29215958/postoperative-complications-of-pars-plana-vitrectomy-for-diabetic-retinal-disease
#1
Gary L Yau, Paolo S Silva, Paul G Arrigg, Jennifer K Sun
Despite recent advances in the medical management of diabetic retinal disease, there remain established indications for vitreoretinal surgery in the treatment of severe proliferative diabetic retinopathy. These include non-clearing vitreous hemorrhage and tractional retinal detachment. Advances in surgical instrumentation, technique, and experience have led to improved visual outcomes, as well as a corresponding decrease in the incidence of postoperative complications. However, the presence of systemic and ocular factors in diabetic patients increases the risk of adverse events compared to non-diabetic individuals...
December 7, 2017: Seminars in Ophthalmology
https://www.readbyqxmd.com/read/29214075/air-bubble-technique-for-fundus-visualization-during-vitrectomy-in-aphakia
#2
Mahmoud Mohamed Farouk, Takeshi Naito, Mohammed Elagouz, Hatem Ammar, Alahmady Hamad Alsmman, Engy Mohamed Mostafa
Purpose: To evaluate the efficacy and safety of air bubble technique for vitrectomy in aphakia. Study Design: Prospective interventional uncontrolled case series. Methods: This study included 53 eyes of 53 patients who are phakic and indicated for phacovitrectomy (7 eyes, group 1), aphakic and indicated for vitrectomy (22 eyes, group 2), or underwent unplanned vitrectomy for immediate management of a phacoemulsification surgery complicated by rupture posterior capsule with dropped nucleus, fragments, or IOL (24 eyes, group 3)...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29214073/assessment-of-ocriplasmin-effects-on-the-vitreoretinal-compartment-in-porcine-and-human-model-systems
#3
Bart Jonckx, Michael Porcu, Aurelie Candi, Isabelle Etienne, Philippe Barbeaux, Jean H M Feyen
Ocriplasmin (Jetrea®) is a recombinant protease used to treat vitreomacular traction. To gain insight into vitreoretinal observations reported after ocriplasmin treatment, we have developed an in vivo porcine ocriplasmin-induced posterior vitreous detachment (PVD) model in which we investigated vitreoretinal tissues by optical coherence tomography, histology, and cytokine profiling. Eight weeks postinjection, ocriplasmin yielded PVD in 82% of eyes. Subretinal fluid (85%) and vitreous hyperreflective spots (45%) were resolved by week 3...
2017: Journal of Ophthalmology
https://www.readbyqxmd.com/read/29210961/therapeutic-vitrectomy-as-an-adjunct-treatment-to-systemic-chemotherapy-for-intraocular-lymphoma
#4
Gregory J Bever, Dan J Kim, Armin R Afshar, James L Rubenstein, Bertil E Damato
PURPOSE: To report the outcome of a previously vitrectomized eye having less lymphoma disease burden compared with the contralateral nonvitrectomized eye over the course of 3.5 years while on systemic chemotherapy. METHODS: Case report. RESULTS: A 51-year-old man with vitreoretinal lymphoma with central nervous system involvement underwent vitrectomy in his left eye. Over the following 3.5 years on systemic chemotherapy, the left eye had less lymphoma disease burden compared with the contralateral nonvitrectomized right eye...
November 23, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29208839/safety-efficacy-and-cost-effectiveness-of-consecutive-bilateral-cataract-surgery-on-two-successive-days-in-tribes-at-base-hospital-through-community-outreach-program-a-prospective-study-of-aravali-mountain-north-west-india
#5
Amit Mohan, Navjot Kaur, Vishal C Bhatanagar
PURPOSE: The aim of the study was to evaluate the safety and efficacy of consecutive bilateral cataract surgery (CBCS) on two successive days in a single hospital visit. METHODS: Prospective study was conducted on 565 patients of various tribes of hilly area of West Rajasthan who had come to our hospital through community outreach programmed (CORP) between January 2015 and March 2016. Patients with significant bilateral cataract without any other ocular morbidity were advised bilateral manual small incision cataract surgery on two consecutive days...
December 2017: Indian Journal of Ophthalmology
https://www.readbyqxmd.com/read/29200823/six-month-postoperative-outcomes-of-intraoperative-oct-guided-surgical-cystotomy-for-refractory-cystoid-macular-edema-in-diabetic-eyes
#6
Yuichi Asahina, Naoko Tachi, Yumi Asahina, Kayoko Yoshimura, Yoshiki Ueta, Yoshihiro Hashimoto
Purpose: This study evaluated the outcomes of surgical cystotomy for recurrent diabetic cystoid macular edema (CME). Patients and methods: We analyzed 20 eyes with a clinical diagnosis of diabetic retinopathy and refractory CME. Release of vitreoretinal adhesion, epiretinal membrane (ERM) and internal limiting membrane (ILM) peeling and cystotomy guided by intraoperative optical coherence tomography (iOCT) were performed in every patient. Pars plana vitrectomy was also performed in 17 patients, 11 of whom also underwent lensectomy and intraocular lens implantation...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29197165/the-treatment-of-postoperative-endophthalmitis-should-we-still-follow-the-endophthalmitis-vitrectomy-study-more-than-two-decades-after-its-publication
#7
Andrzej Grzybowski, Magdalena Turczynowska, Ferenc Kuhn
Conducted in the early 1990s Endophthalmitis Vitrectomy Study (EVS) have helped in establishing reasonable guidelines for the management of infectious postoperative endophthalmitis. However at present, more than 20 years after its publication, tremendous progress has been introduced in vitrectomy technology, which now permits the vitreoretinal surgeon to perform surgery more safely, and with better outcomes. Moerover, performing a complete vitreous removal, along with the moving up of the surgical intervention to as early as possible allows the prevention of complications that would limit the functional improvement postoperatively...
December 2, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29193875/dabigatran-inhibits-intravitreal-thrombin-activity
#8
Jeroen Bastiaans, Verena C Mulder, Jan C van Meurs, Marja Smits-Te Nijenhuis, Conny van Holten-Neelen, P Martin van Hagen, Willem A Dik
PURPOSE: Proliferative vitreoretinopathy (PVR) is a vitreoretinal disorder in which retinal pigment epithelial (RPE) cell activation contributes to both formation of fibrotic retinal membranes and inflammation. Vitreous of patients with PVR contains increased thrombin activity which induces profibrotic and proinflammatory programs in RPE cells. Inhibition of intravitreal thrombin activity may thus represent a therapeutic option for PVR. In this study, we examined the capacity of the clinically available direct thrombin inhibitor dabigatran to inhibit thrombin activity in vitreous fluids...
November 30, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29190243/factors-associated-with-serous-retinal-detachment-in-highly-myopic-eyes-with-vertical-oval-shaped-dome
#9
Antonio García-Ben, María J Morillo Sanchez, Ana Gonzalez Gómez, Ignacio García-Basterra, Antonio Soler García, Jose M García-Campos
PURPOSE: This study investigated factors associated with persistent serous retinal detachment in highly myopic eyes with vertical oval-shaped domes. METHODS: Twenty-eight highly myopic patients (40 eyes) with smooth macular elevations related to a vertical oval-shaped dome were recruited. Serous retinal detachment was investigated; 11 eyes had persistent submacular fluid (study group) and 29 eyes lacked submacular fluid (control group). All patients underwent complete ophthalmologic examinations, including axial-length measurement and fluorescein angiography...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29190238/longitudinal-changes-in-the-optic-nerve-head-and-retina-over-time-in-very-young-children-with-familial-exudative-vitreoretinopathy
#10
Jonghyun Lee, Mays A El-Dairi, Du Tran-Viet, Shwetha Mangalesh, Alexandria Dandridge, Kim Jiramongkolchai, Christian Viehland, Cynthia A Toth
PURPOSE: To explore vitreoretinal pathologies and their longitudinal changes visible on handheld optical coherence tomography (OCT) of young children with familial exudative vitreoretinopathy. METHODS: The authors retrospectively analyzed handheld OCT images for vitreoretinal interface and retinal abnormalities and optic nerve head (ONH) elevation. RESULTS: From 26 eyes of 16 children (mean age 32 months) with familial exudative vitreoretinopathy, 10 had ONH dragging on photographs, and in these, handheld OCT revealed temporal and anterior retinal displacement, prominent vitreopapillary adhesion or traction, and retinal nerve fiber layer thickening at ONH margins with adjacent retinal elevation...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29190237/impact-of-etiology-on-the-outcome-of-pediatric-rhegmatogenous-retinal-detachment
#11
Ying-Chen Huang, Yen-Chang Chu, Nan-Kai Wang, Chi-Chun Lai, Kuan-Jen Chen, Yih-Shiou Hwang, Wei-Chi Wu
PURPOSE: To evaluate the clinical features and surgical outcomes of rhegmatogenous retinal detachment in pediatric patients and to identify the independent effect of each etiology on the outcome. METHODS: A review of patients younger than 18 years who underwent vitreoretinal surgery was conducted at Chang Gung Memorial Hospital, Taoyuan, between 2008 and 2013. Patients were classified according to etiology. Multivariate logistic regression analysis was performed to evaluate the association between outcomes and each etiologic factor...
November 22, 2017: Retina
https://www.readbyqxmd.com/read/29184386/novel-grid-combined-with-peripheral-distortion-correction-for-ultra-widefield-image-grading-of-age-related-macular-degeneration
#12
Patrick Oellers, Inês Laíns, Steven Mach, Shady Garas, Ivana K Kim, Demetrios G Vvvas, Joan W Miller, Deeba Husain, John B Miller
Purpose: Eyes with age-related macular degeneration (AMD) often harbor pathological changes in the retinal periphery and perimacular region. These extramacular changes have not been well classified, but may be phenotypically and functionally relevant. The purpose of this study was to demonstrate a novel grid to systematically study peripheral retinal abnormalities in AMD using geometric distortion-corrected ultra-widefield (UWF) imaging. Methods: This is a cross-sectional observational case series...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29180844/vitreoretinal-interface-abnormalities-in-diabetic-macular-edema-and-effectiveness-of-anti-vegf-therapy-an-optical-coherence-tomography-study
#13
Alexei N Kulikov, Sergei V Sosnovskii, Roman D Berezin, Dmitrii S Maltsev, Dzhambulat H Oskanov, Nikolai A Gribanov
Purpose: To study vitreoretinal interface (VRI) abnormalities in diabetic macular edema (DME) and the influence of these on the effectiveness of intravitreal anti-vascular endothelial growth factor (VEGF) therapy. Methods: VRI status and central retinal thickness (CRT) were evaluated using line and 3D-reference scans obtained using spectral domain-optical coherence tomography RTVue-100 before and 1 month after intravitreal anti-VEGF injection (IVI). VRI status was categorized into five subgroups: normal VRI, retinal surface wrinkling associated with the eccentric epiretinal membrane (ERM), ERM involving the macular center, vitreomacular adhesion (VMA), and vitreomacular traction (VMT)...
2017: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29179221/-vitreomacular-traction-following-anti-vegf-therapy-two-cases
#14
Sophie Helene Wallraf, Kristina Markova, Christos Haritoglou
Vitreomacular traction syndrome (VMTS) is defined as an incomplete or anomalous posterior vitreous detachment resulting in tractional forces at the macular region. In the context of anti-VEGF therapy, the formation of vitreoretinal traction has mainly been reported as a potential complication of VEGF inhibition in ischemic proliferative retinal disease, such as proliferative diabetic retinopathy. In this report, we present two patients who developed VMTS during anti-VEGF therapy for exudative age-related macular degeneration and diabetic macular edema...
November 27, 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29178892/knobloch-syndrome-associated-with-polymicrogyria-and-early-onset-of-retinal-detachment-two-case-reports
#15
Robert J White, Yao Wang, Peter Tang, Sandra R Montezuma
BACKGROUND: Knobloch Syndrome (KS) is a rare congenital syndrome characterized by occipital skull defects and vitreoretinal degeneration. Retinal detachment (RD) often occurs at the end of the first decade of life or later. Aside from occipital skull defects, central nervous system abnormalities are uncommon. CASE PRESENTATIONS: We report on two siblings with KS. The first, a seven month old male, presented with nystagmus and was found to have a serous RD and a tessellated retinal appearance...
November 25, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/29176537/novel-surgical-technique-for-inducing-posterior-vitreous-detachment-during-pars-plana-vitrectomy-for-pediatric-patients-using-a-flexible-loop
#16
Linda A Cernichiaro-Espinosa, Audina M Berrocal
PURPOSE: Vitreoretinal surgical diseases in children are challenging because of the complex features of the vitreous, retina, and the interface between them. Posterior vitreous detachment is a crucial step during vitrectomy. To date, pharmacologic vitreolysis that liquefies the vitreous and disrupts the posterior hyaloid attachment to the retina has been studied. However, there are reports of unexplained adverse effects. We describe a case performed with a reproducible, safe and time-saving technique using a commercially available flexible loop for posterior vitreous detachment induction in a pediatric patient...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29176526/macular-hole-formation-after-pars-plana-vitrectomy-for-primary-vitreoretinal-lymphoma
#17
Masatoshi Haruta, Chikako Taguchi, Ryoji Yamakawa
PURPOSE: To report a case of primary vitreoretinal lymphoma in which a macular hole developed after a diagnostic pars plana vitrectomy. METHODS: A retrospective interventional case report. RESULTS: A 65-year-old woman presented with worsening vision in the left eye. Fundus examination showed vitreous haze and multifocal, yellow-white infiltrates in the retina and under the retinal pigment epithelium in the left eye. She underwent a diagnostic pars plana vitrectomy in that eye...
November 22, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29164983/a-cluster-of-vitreoretinal-lymphoma-in-new-york-with-possible-link-to-the-chernobyl-nuclear-disaster
#18
Sanford Kempin, Paul T Finger, Robert Peter Gale, John Rescigno, Jeffrey Rubin, Walter Choi, Rebecca Fisher, Alexander Aizman, Ilona Genis, Stephen C Malamud, Roxana Moslehi
No abstract text is available yet for this article.
November 22, 2017: Leukemia & Lymphoma
https://www.readbyqxmd.com/read/29160778/optical-coherence-tomography-2-diagnostic-tool-to-study-peripheral-vitreoretinal-pathologies
#19
Matteo G Cereda, Federico Corvi, Mariano Cozzi, Marco Pellegrini, Giovanni Staurenghi
PURPOSE: To investigate the utility of new wide-field optical coherence tomography (OCT) device in the evaluation of mid and far retinal periphery and to show its feasibility and advantages in clinical practice. METHODS: Consecutive patients underwent a complete ophthalmologic examination including standard OCT and new prototype OCT2 derived from Heidelberg Spectralis. RESULTS: Thirty-one eyes of 31 patients were studied with a total of 44 lesions, including 18 retinal detachments, 15 retinal holes and tears, 9 retinoschisis, and 2 retinal tufts...
November 16, 2017: Retina
https://www.readbyqxmd.com/read/29146307/long-term-visual-outcomes-and-safety-profile-of-27-gauge-pars-plana-vitrectomy-for-posterior-segment-disease
#20
M Ali Khan, Alexander Kuley, Christopher D Riemann, Maria H Berrocal, Rohit R Lakhanpal, Jason Hsu, Arunan Sivalingam, Allen C Ho, Carl D Regillo
PURPOSE: To report longer-term outcomes of 27-gauge pars plana vitrectomy (PPV) in eyes with posterior segment disease. DESIGN: Multicenter, retrospective, interventional case series. PARTICIPANTS: A total of 390 eyes of 360 patients undergoing 27-gauge PPV for a vitreoretinal surgery indication. INTERVENTION: Three-port, transconjunctival, 27-gauge PPV. MAIN OUTCOME MEASURES: Change in visual acuity (VA) and occurrence of intraoperative and postoperative complications with a minimum follow-up of 365 days...
November 13, 2017: Ophthalmology
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