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https://www.readbyqxmd.com/read/29664988/peripheral-vascular-abnormalities-seen-by-ultra-widefield-fluorescein-angiography-in-adults-with-history-of-prematurity-report-of-three-cases
#1
Linda Alejandra Cernichiaro-Espinosa, Basil K Williams, María A Martínez-Castellanos, Catherin I Negron, Audina M Berrocal
Retinopathy of prematurity (ROP) may lead to late-developing complications due to the abnormal vitreoretinal interface. In this case report, three adult patients (ages 39 years, 62 years, and 64 years) with a history of prematurity underwent imaging with ultra-widefield fluorescein angiography (UWFFA). The UWFFA demonstrated late peripheral vascular hyperfluorescence in all three patients, perivascular leakage in two of the patients, hyperfluorescent foveal avascular zone in two of the patients, peripheral avascular retina in two of the patients, vasoproliferative tumor in one of the patients, peripheral neovascularization in one of the patients, and vascular anastomosis in one of the patients...
April 1, 2018: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/29658389/comparison-of-endoscopic-assisted-and-temporary-keratoprosthesis-assisted-vitrectomy-in-combat-ocular-trauma-experience-at-a-tertiary-eye-center-in-turkey
#2
Onder Ayyildiz, Ali Hakan Durukan
Objective This study was performed to compare the functional and anatomical results of endoscopic-assisted and temporary keratoprosthesis (TKP)-assisted vitrectomy in patients with combat ocular trauma (COT). Methods The medical records of 14 severely injured eyes of 12 patients who underwent endoscopy or TKP implantation in combination with vitreoretinal surgery from 2007 to 2015 were retrospectively evaluated. The patients' ocular history and functional and anatomic anterior and posterior segment results were analyzed...
January 1, 2018: Journal of International Medical Research
https://www.readbyqxmd.com/read/29657974/monocular-and-binocular-visual-impairment-in-the-uk-biobank-study-prevalence-associations-and-diagnoses
#3
Martin McKibbin, Tracey M Farragher, Darren Shickle
Objective: To determine the prevalence of, associations with and diagnoses leading to mild visual impairment or worse (logMAR >0.3) in middle-aged adults in the UK Biobank study. Methods and analysis: Prevalence estimates for monocular and binocular visual impairment were determined for the UK Biobank participants with fundus photographs and spectral domain optical coherence tomography images. Associations with socioeconomic, biometric, lifestyle and medical variables were investigated for cases with visual impairment and matched controls, using multinomial logistic regression models...
2018: BMJ Open Ophthalmology
https://www.readbyqxmd.com/read/29649485/occult-globe-rupture-diagnostic-and-treatment-challenge
#4
REVIEW
Argyrios Chronopoulos, Jong Min Ong, Gabriele Thumann, James S Schutz
Occult globe rupture is a traumatic dehiscence of the sclera at or posterior to the rectus muscle insertions without a visible eye wall defect on slit lamp examination. Occult scleral ruptures are important because they can be difficult to diagnose, but normally require preoperative protection against external pressure to reduce risk of herniation of ocular contents through the rupture and then urgent surgical repair to restore eye wall structural integrity and achieve optimum prognosis. A deeper than normal anterior chamber with posteriorly retracted plateau iris seen immediately after acute ocular trauma is virtually pathognomonic of posterior globe dehiscence...
April 9, 2018: Survey of Ophthalmology
https://www.readbyqxmd.com/read/29643781/two-cases-of-rhegmatogenous-retinal-detachment-associated-with-asteroid-hyalosis
#5
Yoshitaka Okuda, Keigo Kakurai, Takaki Sato, Seita Morishita, Masanori Fukumoto, Ryohsuke Kohmoto, Mai Takagi, Takatoshi Kobayashi, Teruyo Kida, Tsunehiko Ikeda
Background: To report two cases of rhegmatogenous retinal detachment (RRD) associated with asteroid hyalosis (AH). Case Presentation: Two patients presented with RRD originating from a flap tear. Case 1 involved a 62-year-old male who was found to have bullous RRD in his left eye originating from a flap tear. During vitreous surgery, a thick vitreous cortex was found to have strongly adhered to the entire retinal surface, from the center to the periphery. A bimanual method was then used in conjunction with the vitrectomy to create an artificial posterior vitreous detachment...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29643777/a-case-of-retinal-detachment-with-unique-optical-coherence-tomography-findings-after-gamma-knife%C3%A2-radiosurgery-treatment-for-choroidal-melanoma
#6
Daisaku Kimura, Teruyo Kida, Takaki Sato, Masanori Fukumoto, Ryohsuke Kohmoto, Shota Kojima, Hiroshi Mizuno, Hitoshi Sakaguchi, Jun Sugasawa, Tsunehiko Ikeda
Purpose: To report a case of retinal detachment with unique optical coherence tomography (OCT) findings after Gamma Knife® (GK; Elekta Instrument AB, Stockholm, Sweden) treatment for choroidal melanoma (CM). Case Report: A 48-year-old woman underwent GK therapy for CM in her right eye from the macula to the temporal side. While the tumor subsequently shrank, the patient developed radiation retinopathy, which was treated with laser photocoagulation. The tumor lesions later subsided; however, her visual acuity (VA) decreased 8 years after the initial treatment...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29643775/case-report-of-a-family-affected-by-stickler-syndrome-in-which-rhegmatogenous-retinal-detachment-occurred-in-five-eyes-of-three-siblings
#7
Daisaku Kimura, Takaki Sato, Shou Oosuka, Ryohsuke Kohmoto, Masanori Fukumoto, Masashi Mimura, Kensuke Tajiri, Takatoshi Kobayashi, Teruyo Kida, Tsunehiko Ikeda
Purpose: Stickler syndrome is an autosomal dominant inherited disorder that is well known to be highly associated with the development of rhegmatogenous retinal detachment. In this study, we report the case of a family affected by Stickler syndrome in which rhegmatogenous retinal detachment developed in 5 eyes of 3 siblings. Case Series: For treatment, we performed vitreous surgery on 1 eye of the eldest son, and bilateral scleral buckling surgery on the 2 younger children...
January 2018: Case Reports in Ophthalmology
https://www.readbyqxmd.com/read/29624544/differences-in-refractive-outcomes-between-phacoemulsification-for-cataract-alone-and-combined-phacoemulsification-and-vitrectomy-for-epiretinal-membrane
#8
Lynn Shi, Jonathan S Chang, Leejee H Suh, Stanley Chang
PURPOSE: To determine whether preoperative adjustments are required for intraocular lens calculations in combined phacovitrectomy surgery. METHODS: A single-center, retrospective study of 50 eyes that underwent combined phacovitrectomy and a control group of 50 eyes after cataract surgery over a 3-year period by a single anterior segment surgeon and a single posterior segment surgeon. Main outcome measures were predicted refractive error (RE), as determined by SRK/T and Holladay 1 formulas, change compared with actual RE, surgically induced astigmatism, and the relationships between preoperative central foveal thickness or change in central foveal thickness and final RE...
April 5, 2018: Retina
https://www.readbyqxmd.com/read/29623462/long-term-follow-up-of-lamellar-macular-holes-and-pseudoholes-over-at-least-5-years
#9
K Purtskhvanidze, L Balken, T Hamann, L Wöster, C von der Burchard, J Roider, Felix Treumer
PURPOSE: To assess morphological and functional changes of lamellar macular holes and pseudoholes with or without vitrectomy and membrane peeling with at least 5 years follow-up. METHODS: Retrospective study of 73 eyes with lamellar macular hole (LH, n = 28), macular pseudohole (PH, n = 31), and pseudohole with cleaved edges (cleavedPH, n = 14). Forty-six eyes were merely observed without vitreoretinal intervention (observation group), and 27 eyes underwent vitrectomy with membrane peeling (vitrectomy group)...
April 6, 2018: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/29621510/peripheral-changes-associated-with-delayed-dark-adaptation-in-age-related-macular-degeneration
#10
Inês Laíns, Dong Ho Park, Ryo Mukai, Rebecca Silverman, Patrick Oellers, Steven Mach, Ivana K Kim, Demetrios G Vavvas, Joan W Miller, John B Miller, Deeba Husain
PURPOSE: To study the association between peripheral changes in Age-related Macular Degeneration (AMD) and dark adaptation (DA). DESIGN: Prospective, cross-sectional study. METHODS: We recruited patients with AMD and a control group (> 50 years) without any vitreoretinal disease. Ultra-widefield (UWF) pseudocolor and fundus autofluorescence (FAF) (Optos Inc, MA) were obtained, and were assessed by two graders for the presence of several peripheral changes in perimacular, mid- and far-peripheral zones...
April 2, 2018: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/29613981/phacomorphic-angle-closure-following-silicone-oil-tamponade-in-a-pediatric-patient
#11
Victoria C Leung, Simon Fung, Rajeev Muni, Asim Ali
PURPOSE: To report a case of phacomorphic glaucoma following retinal detachment repair with silicone oil in a pediatric patient. STUDY DESIGN: Case report. METHODS: A chart review was conducted at St. Michael's Hospital and The Hospital for Sick Children (Toronto, Canada), where the patient received ophthalmic care from July 28, 2015 onwards. RESULTS: A 14 year-old boy with a history of traumatic retinal detachment and proliferative vitreoretinopathy in the left eye, requiring two pars plana vitrectomies, membrane peel, and silicone oil tamponade, presented with one-day history of decreased vision in the left eye, severe headache, nausea, and vomiting...
April 2, 2018: Journal of Glaucoma
https://www.readbyqxmd.com/read/29607665/toxicity-and-phototoxicity-in-human-arpe-19-retinal-pigment-epithelium-cells-of-dyes-commonly-used-in-retinal-surgery
#12
Doaa Awad, Joanna Wilińska, Dimitra Gousia, Xiaoye Shi, Jnina Eddous, Arne Müller, Veit Wagner, Charlie Hillner, Werner Brannath, Andreas Mohr, Detlef Gabel
PURPOSE: To compare, for the first time, systematically the toxicity and phototoxicity of dyes and dye combinations used in vitreoretinal surgery. The dyes were trypan blue, brilliant blue G, trypan blue + brilliant blue G, indocyanine green, bromophenol blue, bromophenol blue + brilliant blue G, and acid violet 17, in clinically used concentrations. METHODS: Human ARPE retinal pigment epithelium cells were exposed to the dyes for 30 min. For phototoxicity, the cells were exposed for 15 min to high-intensity light from a light emitting diode source with an intensity similar to surgical conditions...
March 1, 2018: European Journal of Ophthalmology
https://www.readbyqxmd.com/read/29600187/endoscopy-assisted-vitrectomy-in-the-anterior-vitreous
#13
REVIEW
Yong-Zhen Yu, Yu-Ping Zou, Xiu-Lan Zou
Endoscopy-assisted ocular surgery is a relatively old technique that is increasingly being recognized for its application in cases of vitreoretinal disease. This technique is especially useful when both the vitreous and retina are difficult to access because of media opacity, a small pupil, or a microcornea. In this context, the anterior vitreous is often difficult to dissect because of its complex pathological changes. This article reviews the common anatomical features and pathologies that are observed in the anterior vitreous, as well as the applications and indications of endoscopy-assisted vitrectomy in the anterior vitreous...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29600174/outcomes-of-transconjunctival-sutureless-27-gauge-vitrectomy-for-vitreoretinal-diseases
#14
Jie Li, San-Mei Liu, Wen-Tao Dong, Fang Li, Cai-Hong Zhou, Xiao-Dan Xu, Jie Zhong
AIM: To evaluate the safety and efficacy profile of 27-gauge (27G) pars plana vitrectomy (PPV) for the treatment of various vitreoretinal diseases. METHODS: The clinical outcomes of 61 eyes (58 patients) with various vitreoretinal diseases following 27G PPV were retrospectively reviewed. RESULTS: Surgical indications included rhegmatogenous retinal detachment ( n =24), full-thickness macular hole ( n =12), diabetic retinopathy ( n =11), vitreous hemorrhage ( n =6), Eales disease ( n =4), pathological myopia-related vitreous floater ( n =2), and macular epiretinal membrane ( n =2)...
2018: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29599249/acute-retinal-toxicity-associated-with-a-mixture-of-perfluorooctane-and-perfluorohexyloctane-failure-of-another-indirect-cytotoxicity-analysis
#15
Rosa M Coco, Girish K Srivastava, Cristina Andrés-Iglesias, Jesús Medina, Fernando Rull, Alvaro Fernandez-Vega-Gonzalez, Ivan Fernandez-Bueno, Antonio Dueñas, Jose C Pastor
AIMS: To report new information related to acute retinal toxicity of Bio Octane Plus, a mixture of 90% perfluorooctane (PFO) and 10% perfluorohexyloctane. METHODS: This retrospective, descriptive case series reports the occurrence of acute retinal toxicity after vitreoretinal surgery in which Bio Octane Plus (batch number 1605148) was used as an endotamponade. Cytotoxicity biocompatibility tests and chemical analyses by Fourier-transformed infrared (FTIR) spectroscopy and gas chromatography-mass spectrometry (GC-MS) of the presumed toxic product were performed...
March 29, 2018: British Journal of Ophthalmology
https://www.readbyqxmd.com/read/29593379/the-clinical-effectiveness-of-tafluprost-on-japanese-normal-tension-glaucoma-patients
#16
Akio Nomura, Hirotaka Osaki, Fumiki Shimada, Yasuaki Kuwayama
Purpose: This study evaluates the effect of tafluprost on visual field progression in normal-tension glaucoma (NTG) in a Japanese population under daily clinical practice settings. Patients and methods: This is a post-marketing, multicenter, non-interventional, observational study. Patients with NTG who initiated tafluprost treatment were registered and prospectively observed for 2-3 years to investigate its effectiveness on visual field progression and intraocular pressure (IOP) and safety in Japan...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29592990/management-of-a-rhegmatogenous-retinal-detachment-in-a-low-resource-setting-treatment-options-when-there-is-no-vitreoretinal-surgeon
#17
Elizabeth Emsley, P J Steptoe, Sunildath Cazabon
We discuss the case of a 49-year-old soldier with a macula-on rhegmatogenous retinal detachment in Sierra Leone. The case highlights the challenge of accessing visually preserving ophthalmic specialist care in sub-Saharan Africa (SSA) for vitreoretinal (VR) disease. It highlights a shortage of VR surgeons in SSA, limited examination facilities, the larger issue of accessing specialist care urgently and the costs associated with accessing surgery out-of-country. It also identifies a shortage in epidemiological data on the issue which limits the assessment of the scale of the problem...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29589147/-primary-vitreoretinal-lymphoma
#18
D Jaehne, S E Coupland
Primary vitreoretinal lymphoma (PVRL) is the most common intraocular lymphoma. It is a high grade malignant B‑cell lymphoma, which is thought to arise in the retina. It often infiltrates the central nervous system (CNS) and is therefore associated with a poor prognosis. The PVRL must be differentiated from other forms of intraocular lymphoma, such as the low-grade B‑cell lymphoma that rarely arises in the choroid. The choroidal lymphomas do not spread to the brain, they can be treated with low-dose external beam radiotherapy and the patients have a good prognosis...
March 27, 2018: Der Ophthalmologe: Zeitschrift der Deutschen Ophthalmologischen Gesellschaft
https://www.readbyqxmd.com/read/29588570/pneumatic-retinopexy-patient-selection-and-specific-factors
#19
REVIEW
Stephen Stewart, Wing Chan
Pneumatic retinopexy is a minimally invasive, non-incisional procedure for repairing retinal detachment. This procedure is associated with reduced morbidity, reduced cost and faster postoperative recovery compared to pars plana vitrectomy and scleral buckling. Superior visual acuity outcomes have also been reported. Intraoperative complications are primarily related to the intraocular pressure rise caused by gas injection, or the misdirection of the gas. There is a low rate of postoperative complications. Anatomic success rates of over 90% can be achieved when strict selection criteria are applied...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29584529/characterization-and-pharmacokinetics-of-triamcinolone-acetonide-loaded-liposomes-topical-formulations-for-vitreoretinal-drug-delivery
#20
Juan C Altamirano-Vallejo, Jose Navarro-Partida, Alejandro Gonzalez-De la Rosa, Jane H Hsiao, Jose S Olguín-Gutierrez, Ana C Gonzalez-Villegas, Brian C Keller, Lourdes Bouzo-Lopez, Arturo Santos
PURPOSE: To achieve a safer alternative to intravitreal injection of corticosteroids, we developed and characterized triamcinolone acetonide-loaded liposomes formulations (TA-LFs) to be used topically for vitreoretinal drug delivery. METHODS: Four different 0.2% TA-LFs (TA-LF1 to TA-LF4) were generated and submitted to physicochemical characterization. Posteriorly, an ex vivo diffusion assay was performed using rabbit corneas as membranes. Finally, concentrations of triamcinolone acetonide (TA) were determined by high-performance liquid chromatography in ocular tissues from New Zealand white rabbits after multiple topical doses of TA-LF2 (6 times per day, 14 days)...
March 27, 2018: Journal of Ocular Pharmacology and Therapeutics
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