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https://www.readbyqxmd.com/read/29054616/green-synthesized-nanoclusters-of-ultra-small-zero-valent-iron-nanoparticles-as-a-novel-dye-removing-material
#1
Alireza Ebrahiminezhad, Saeed Taghizadeh, Younes Ghasemi, Aydin Berenjian
Iron based nanoparticles have gained much attention in recent years due to their unique physicochemical properties especially in the environmental remediation practices. There has been an increasing demand for new sustainable techniques for production of these nanoparticles. In the present work, a novel iron nanostructure was successfully fabricated by a facile and green approach using the aqueous extract of Mediterranean cypress (Cupressus sempervirens). In fact, nanoclusters of highly reactive ultra-small (~1...
October 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29053630/rapid-classification-and-identification-of-chemical-components-of-schisandra-chinensis-by-uplc-q-tof-ms-combined-with-data-post-processing
#2
Shenshen Yang, Lanlan Shan, Houmin Luo, Xue Sheng, Jun Du, Yubo Li
Schisandra chinensis (known in Chinese as WuWeiZi, WWZ) has observable effects such as astringing the lung to stop coughs, arresting sweating, preserving semen and preventing diarrhea. The major components of WWZ include lignans, triterpenoids, organic acids and fatty acids. In this paper, a reliable method for the rapid identification of multiple components in WWZ by their characteristic fragments and neutral losses using UPLC-Q-TOF/MS technology was developed. After review of the literature and some reference experiments, the fragmentation pattern of several compounds were studied and summarized...
October 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29053616/valorization-challenges-to-almond-residues-phytochemical-composition-and-functional-application
#3
REVIEW
Iva Prgomet, Berta Gonçalves, Raúl Domínguez-Perles, Núria Pascual-Seva, Ana I R N A Barros
Almond is characterized by its high nutritional value; although information reported so far mainly concerns edible kernel. Even though the nutritional and commercial relevance of the almond is restricted to almond meat; to date; increasing attention has been paid to other parts of this fruit (skin; shell; and hull); considered by-products that are scarcely characterized and exploited regarding their properties as valuable sources of bioactive compounds (mainly represented by phenolic acids and flavonoids). This lack of proper valorization procedures entails the continuation of the application of traditional procedures to almond residues that nowadays are mainly addressed to livestock feed and energy production...
October 20, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29052027/four-new-diterpenoid-alkaloids-from-aconitum-japonicum-subsp-subcuneatum
#4
Hiroshi Yamashita, Keiko Takeda, Machiko Haraguchi, Yuki Abe, Natsumi Kuwahara, Shota Suzuki, Ayaka Terui, Takumi Masaka, Naoko Munakata, Mariko Uchida, Masashi Nunokawa, Kyousuke Kaneda, Masuo Goto, Kuo-Hsiung Lee, Koji Wada
Diterpenoid alkaloids with remarkable chemical properties and biological activities are frequently found in plants of the genera Aconitum, Delphinium, and Garrya. Accordingly, several diterpenoid alkaloid constituents of Aconitum and Delphinium plants as well as their derivatives exhibited cytotoxic activity against lung, prostate, nasopharyngeal, and vincristine-resistant nasopharyngeal cancer cell lines. Four new C19-diterpenoid alkaloids, 14-anisoyllasianine (1), 14-anisoyl-N-deethylaconine (2), N-deethylaljesaconitine A (3), and N-deethylnevadensine (4), together with 17 known C19- and C20-diterpenoid alkaloids, were isolated in a phytochemical investigation of rhizoma of Aconitum japonicum THUNB...
October 19, 2017: Journal of Natural Medicines
https://www.readbyqxmd.com/read/29049940/photocatalytic-degradation-of-synthetic-food-dye-sunset-yellow-fcf-fd-c-yellow-no-6-by-ailanthus-excelsa-roxb-possessing-antioxidant-and-cytotoxic-activity
#5
Subramanyam Deepika, Rajendran Harishkumar, Murugesan Dinesh, Rajadurai Abarna, Moorthy Anbalagan, Selvaraj Mohana Roopan, Chinnadurai Immanuel Selvaraj
The purpose of our work is to identify the bioactive compounds of bark and leaves extract from Ailanthus excelsa Roxb. and to explore its effectiveness against synthetic food dye. The presence of primary and secondary metabolites was confirmed by carrying out phytochemicals analysis. With the prior knowledge accessible on the indispensable secondary metabolites holding antioxidant and cytotoxicity activity, the quantitative screening of total phenolic and flavonoid content in methanolic and aqueous extract of bark and leaves from Ailanthus excelsa were done...
October 12, 2017: Journal of Photochemistry and Photobiology. B, Biology
https://www.readbyqxmd.com/read/29048399/rapid-screening-of-active-components-with-an-osteoclastic-inhibitory-effect-in-herba-epimedii-using-quantitative-pattern-activity-relationships-based-on-joint-action-models
#6
Xiao-Yan Yuan, Meng Wang, Sheng Lei, Qian-Xu Yang, Yan-Qiu Liu
Screening of bioactive components is important for modernization and quality control of herbal medicines, while the traditional bioassay-guided phytochemical approach is time-consuming and laborious. The presented study proposes a strategy for rapid screening of active components from herbal medicines. As a case study, the quantitative pattern-activity relationship (QPAR) between compounds and the osteoclastic inhibitory effect of Herba epimedii, a widely used herbal medicine in China, were investigated based on joint models...
October 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29048380/hop-phytochemicals-and-their-potential-role-in-metabolic-syndrome-prevention-and-therapy
#7
REVIEW
Pavel Dostálek, Marcel Karabín, Lukáš Jelínek
Historically, hop cones (Humulus lupulus) have been used since ancient times as a remedy for many ailments and, as a source of polyphenols and bitter acids, is very effective in the treatment of metabolic syndrome (MS). Hop flavonoids, particularly xanthohumol (XN), are substances with hypoglycemic, antihyperlipidemic, and antiobesity activities. Iso-α-acids (IAA) and matured hop bitter acids (MHBA) improve health by influencing lipid metabolism, glucose tolerance, and body weight. The modulatory effect of IAA and MHBA on lipid metabolism may also be responsible for a loss in body weight...
October 19, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29047314/phytochemical-investigation-and-acetylcholinesterase-inhibitory-activity-of-bark-of-hymenodictyon-orixense
#8
Nattawut Suchaichit, Somdej Kanokmedhakul, Kwanjai Kanokmedhakul, Panawan Moosophon, Chantana Boonyarat, Kusawadee Plekratoke, Ruchanok Tearavarich, Natcha P Suchaichit
The chemical investigation of the methanol extract of Hymenodictyon orixense bark, a Thai medicinal herb, provided five compounds. Their structures were identified on the basis of 1D NMR and MS data, as well as by comparison of the data with published values, as an iridoid glycoside: loganin (1), four coumarins: scopoletin (2), scopolin (3), hymexelsin (4) and scopoletin 7-O-β-D-xylopyranosyl-(1→6)-β-D-glucopyranoside (5). Compounds 1-5 showed acetylcholinesterase (AChE) inhibitory activity in the range of 13...
October 19, 2017: Natural Product Research
https://www.readbyqxmd.com/read/29045823/traditional-uses-phytochemistry-and-pharmacological-properties-of-african-nauclea-species-a-review
#9
REVIEW
Romain Haudecoeur, Marine Peuchmaur, Basile Pérès, Maxime Rome, Germain Sotoing Taïwe, Ahcène Boumendjel, Benjamin Boucherle
ETHNOPHARMACOALOGICAL RELEVANCE: The genus Nauclea in Africa comprises seven species. Among them, N. latifolia, N. diderrichii and N. pobeguinii are widely used by the local population in traditional remedies. Preparation from various parts of plants (e.g. roots, bark, leaves) are indicated by traditional healers for a wide range of diseases including malaria, pain, digestive ailments or metabolic diseases. MATERIALS AND METHODS: A literature search was conducted on African species of the genus Nauclea using scientific databases such as Google Scholar, Pubmed or SciFinder...
October 15, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29044724/tea-polyphenols-for-the-prevention-of-uvb-induced-skin-cancer
#10
REVIEW
Pooja Sharma, Mary Katherine Montes de Oca, Amena R Alkeswani, Sarah F McClees, Tanushree Das, Craig A Elmets, Farrukh Afaq
Skin cancer is the most common type of cancer with increasing incidence rate and public health burden. Solar Ultraviolet (UV) radiation causes an array of damaging cellular and molecular events that eventually lead to the development of skin cancer. Despite increased awareness about sun protection, the exposure rate remains high with less than 15% of men and 30% of women using sunscreen on a regular basis. Therefore, there is an imperative need for the development of novel preventive approaches. Skin cancer chemoprevention using phytochemicals either as dietary supplements or by topical applications has gained considerable attention due to their low toxicity, availability, and anti-carcinogenic properties...
October 16, 2017: Photodermatology, Photoimmunology & Photomedicine
https://www.readbyqxmd.com/read/29043349/comparative-suppressing-effects-of-black-and-green-teas-on-the-formation-of-advanced-glycation-end-products-ages-and-age-induced-oxidative-stress
#11
P Ramlagan, P Rondeau, C Planesse, V S Neergheen-Bhujun, E Bourdon, T Bahorun
This study aimed at investigating and comparing the anti-diabetic potential of black and green teas. Biochemical analyses indicate higher antioxidant potency, significantly correlated with the phytochemicals present, in green teas compared to black teas. Both extracts afforded a similar level of protection to erythrocytes against peroxyl radical-induced lysis. Non-cytotoxic concentration of green and black tea extracts significantly reduced the reactive oxygen species (ROS) production (P < 0.01), lowered the oxidation of proteins (P < 0...
October 18, 2017: Food & Function
https://www.readbyqxmd.com/read/29043224/optimization-of-mixing-ratio-to-improve-antioxidant-activity-of-aged-garlic-with-pine-needle-using-response-surface-methodology
#12
Jae-Hee Park, Eunji Shin, Eunju Park
Aged garlic has been reported to possess beneficial pharmacological activities, including anti-stress and anti-fatigue properties, and to exert protective effects on the cardiovascular system and liver. Pine needles are widely used in folk medicine and as food additives owing to their pharmacological properties such as anti-aging and anti-inflammatory effects. It has long been known that combining certain phytochemicals with other phenols or organic acids can produce synergistic effects. Therefore, the purpose of this study was to develop an optimal formula of aged garlic with added pine needle powder for improved antioxidant activity using the statistical technique of response surface methodology...
September 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29043216/proximate-phytochemical-and-in-vitro-antimicrobial-properties-of-dried-leaves-from-ocimum-gratissimum
#13
Justina Y Talabi, Solomon Akinremi Makanjuola
Ocimum gratissimum is a common plant in the tropics and has been used in food and medicine. Its usage in food and medicine could be attributed to its phtyochemical and antimicrobial properties. In this study we investigated the proximate, phytochemical, and antimicrobial attributes of air dried leaves of O. gratissimum. The aqueous extract was found to contain phtyochemicals with alkaloid and saponin present in appreciable amounts. The proximate analysis (crude protein and crude fibre content were 15.075% and 17...
September 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29042289/current-evidence-on-the-effect-of-dietary-polyphenols-intake-on-chronic-diseases
#14
REVIEW
Chiara Costa, Aristidis Tsatsakis, Charalampos Mamoulakis, Michele Teodoro, Giusi Briguglio, Emanuela Caruso, Dimitris Tsoukalas, Denisa Margina, Efthimios Dardiotis, Demetrios Kouretas, Concettina Fenga
Polyphenols are secondary metabolites of plants. They comprise several antioxidant compounds and they are generally considered to be involved in the defense against human chronic diseases. During the last years, there has been growing scientific interest in their potential health benefits. In this comprehensive review, we focus on the current evidence defining the position of their dietary intake in the prevention/treatment of human chronic diseases, including prostate cancer and other types of cancer, cardiovascular diseases, diabetes mellitus and neurodegenerative diseases such as Alzheimer's and Parkinson's disease; we also discuss their ability to modulate multiple signalling transduction pathways involved in the pathophysiology of these diseases...
October 14, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29042287/the-genus-lycium-as-food-and-medicine-a-botanical-ethnobotanical-and-historical-review
#15
REVIEW
Ruyu Yao, Michael Heinrich, Caroline S Weckerle
ETHNOPHARMACOLOGICAL RELEVANCE: Lycium is widely distributed in the arid to semi-arid environments of North and South America, Africa, and Eurasia. In recent years, Lycium barbarum and L. chinense have been advertised as "superfood" with healthy properties. Despite of its popularity, there is a lack of an integrated and critical appraisal of the existing evidence for the use of Lycium. AIM OF THE STUDY: There is a need to understand: 1) Which species were used and how the uses of Lycium developed spatially and over time, 2) how uses differ among regions with different culture backgrounds, and 3) how traditional and current therapeutic and preventive health claims correlate with pharmacological findings...
October 14, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29040837/grape-intake-reduces-thrombin-generation-and-enhances-plasma-fibrinolysis-potential-role-of-circulating-procoagulant-microparticles
#16
Concetta T Ammollo, Fabrizio Semeraro, Rosa Anna Milella, Donato Antonacci, Nicola Semeraro, Mario Colucci
Phytochemicals contained in grapes down-regulate several prothrombotic pathways in vitro. We evaluated the effect of grape consumption on coagulation and fibrinolysis in healthy volunteers. Thirty subjects were enrolled: 20 were given grape (5 g/kg body weight/day for 3 weeks), while 10 served as controls. Blood samples were taken at baseline (T0), at the end of the grape diet (T1) and after 4-week wash-out (T2). Grape intake caused a significant decrease of the procoagulant and inflammatory responses of whole blood and/or mononuclear cells to bacterial lipopolysaccharide at both T1 and T2...
September 1, 2017: Journal of Nutritional Biochemistry
https://www.readbyqxmd.com/read/29039792/health-promoting-phytochemicals-from-11-mustard-cultivars-at-baby-leaf-and-mature-stages
#17
Marissa D Frazie, Moo Jung Kim, Kang-Mo Ku
Mustard is a Brassica vegetable that provides a number of phytonutrients. However, the phytonutrient profile of mustard has been relatively limited. We analyzed the glucosinolates and their hydrolysis products, carotenoids, total anthocyanin and phenolic contents, and antioxidant capacity of the leaves of 11 mustard cultivars grown in a greenhouse at the baby leaf and mature stages. An aliphatic glucosinolate sinigrin and its hydrolysis products allyl isothiocyanate and 1-cyano-2,3-epithiopropane were the major phytonutrients in the mustard leaves...
October 17, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29039667/pretreatment-with-phytochemicals-to-reduce-secondary-effects-of-traumatic-brain-injury
#18
John W Finley
No abstract text is available yet for this article.
October 17, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29039323/antipyretic-effects-of-hydro-methanol-extract-of-melia-azedarach-linn-seeds-and-cucumis-melo-linn-seeds-in-experimental-rabbits
#19
Sabira Sultana, Naveed Akhtar, Hafiz Muhammad Asif
To investigate the antipyretic activity of hydro-methanol extract of Melia azedarach Linn. (HMEMA) seeds and Cucumis melo Linn. (HMECM) seeds in experimental animals. Baker's yeast was used to induce fever in rabbits which were divided into six groups. The animal groups were thereafter administered distilled water (control), paracetamol (reference standard, 150mg/kg), HMEMA (250mg/kg), HMEMA (500mg/kg), HMECM (250mg/kg) and HMECM (500mg/kg) respectively. HMEMA and HMECM were also phytochemically screened for tannins, alkaloids, phenols, flavonoids, saponins and cardiac glycosides...
July 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29037720/mass-spectrometry-based-phytochemical-screening-for-hypoglycemic-activity-of-fagioli-di-sarconi-beans-phaseolus-vulgaris-l
#20
Raffaella Pascale, Giuliana Bianco, Tommaso R I Cataldi, Philippe-Schmitt Kopplin, Federica Bosco, Lisiana Vignola, Jenny Uhl, Marianna Lucio, Luigi Milella
The present study deals with the evaluation of antidiabetic activities of Fagioli di Sarconi beans (Phaseolus vulgaris), including 21 ecotypes protected by the European Union with the mark PGI (i.e., Protected Geographical Indication), and cultivated in Basilicata (southern Italy). For this purpose, α-glucosidase and α-amylase assays were assessed; among all bean ecotypes, the tight green seed colour of Verdolino extracts exhibited the highest α-glucosidase and α-amylase inhibitory activity with IC50=1...
March 1, 2018: Food Chemistry
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