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https://www.readbyqxmd.com/read/29235279/-advance-of-a-representative-traditional-tibetan-medicine-meconopsis-horridula-on-its-phytochemical-and-pharmacological-aspects
#1
REVIEW
Feng Zhao, He-Xin-Ge Zhang, Rui-Feng Bai, Bing-Zhao Tu, Xiao-Li Gao, Peng-Fei Tu, Xing-Yun Chai
Meconopsis horridula is one of alpine plants belonging to family Papaveraceae, mainly distributed in Himalaya Range area. M. horridula is a rare alpine flower, and is a kind of traditional Tibetan medicine, which has been included in more than 40 compound formulae, having efficacies of clearing away heat and alleviating pain, activating blood circulation to remove stasis, traditionally used for the treatment of fractures, injuries, and chest and back pains. Modern research shows that the whole plant of M. horridula contains alkaloids, flavonoids, and terpenes, and its pharmacological activities including antitumor, antivirus and myocardial protection etc...
October 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29235078/the-nutritional-and-phytochemical-composition-of-the-indigenous-australian-pindan-walnut-terminalia-cunninghamii-kernels
#2
Liezhou Zhong, Janet F Bornman, Gangcheng Wu, Aline Hornoff, Koya Ange Pamela Dovi, Hayder Al-Ali, Naveed Aslam, Stuart K Johnson
Nutritional composition of the kernels of two types of Pindan walnut (Terminalia cunninghamii), a native nut consumed traditionally by Australian Indigenous peoples, is reported for the first time. Results showed that Pindan walnut kernels contained high levels of fat, protein and ash, approximately 50, 30 and 5% fresh basis, respectively. The levels of minerals in the kernels were much higher than common walnuts and macadamia nuts, especially those of phosphorus, magnesium and zinc. The high amounts of polyphenols in the kernels provided strong hydrophilic antioxidant capacities, of up to 2004 mg Trolox equivalents/100 g fresh basis using the hydrophilic oxygen radical absorbance capacity assay...
December 12, 2017: Plant Foods for Human Nutrition
https://www.readbyqxmd.com/read/29234699/dataset-on-analysis-of-dyeing-property-of-natural-dye-from-thespesia-populnea-bark-on-different-fabrics
#3
Kuchekar Mohini, Landge Tejashree, Navghare Vijay
The natural dyes separated from plants are of gaining interest as substitutes for synthetic dyes in food and cosmetics. Thespesia populnea (T. populnea) is widely grown plant and used in the treatment of various diseases. This study was aimed to separate natural dye from T. populnea bark and analysis of its dyeing property on different fabrics. In this investigation pharmacognostic study was carried out. The pharmacognostic study includes morphological study, microscopical examination, proximate analysis along with the phytochemical study...
February 2018: Data in Brief
https://www.readbyqxmd.com/read/29234485/regulation-of-sirtuin-mediated-protein-deacetylation-by-cardioprotective-phytochemicals
#4
REVIEW
Niria Treviño-Saldaña, Gerardo García-Rivas
Modulation of posttranslational modifications (PTMs), such as protein acetylation, is considered a novel therapeutic strategy to combat the development and progression of cardiovascular diseases. Protein hyperacetylation is associated with the development of numerous cardiovascular diseases, including atherosclerosis, hypertension, cardiac hypertrophy, and heart failure. In addition, decreased expression and activity of the deacetylases Sirt1, Sirt3, and Sirt6 have been linked to the development and progression of cardiac dysfunction...
2017: Oxidative Medicine and Cellular Longevity
https://www.readbyqxmd.com/read/29234421/comparative-phytochemical-profiling-and-in-vitro-antioxidant-activity-of-extracts-from-raw-materials-tissue-cultured-plants-and-callus-of-oroxylum-indicum-l-vent
#5
Piyanuch Rojsanga, Somnuk Bunsupa, Adelheid H Brantner, Pongtip Sithisarn
Extracts from raw materials from different plant parts, tissue-cultured plants, and callus cultures of Oroxylum indicum were analyzed for in vitro antioxidant activities determined by DPPH radical scavenging assay and evaluated for phytochemical profiles by TLC and LC-MS methods. The results were analyzed by principal component analysis (PCA) to evaluate the similarity. Stalk, pedicel, flower, seed, and whole fruit and callus extracts promoted strong antioxidant activity with high total phenolic and total flavonoid contents...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234406/amelioration-of-scopolamine-induced-learning-and-memory-impairment-by-%C3%AE-pinene-in-c57bl-6-mice
#6
Gil-Yong Lee, Chan Lee, Gyu Hwan Park, Jung-Hee Jang
Increasing evidence suggests that neurodegenerative disorders such as Alzheimer's disease (AD) are mediated via disruption of cholinergic neurons and enhanced oxidative stress. Therefore, attention has been focused on searching for antioxidant phytochemicals for the prevention and/or treatment of AD through their ability to fortify cholinergic function and antioxidant defense capacity. In this study, we have investigated the neuroprotective effect of α-pinene (APN) against learning and memory impairment induced by scopolamine (SCO, 1 mg/kg, i...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234384/screening-of-natural-bioactive-metabolites-and-investigation-of-antioxidant-antimicrobial-antihyperglycemic-neuropharmacological-and-cytotoxicity-potentials-of-litsea-polyantha-juss-ethanolic-root-extract
#7
Nripendra Nath Biswas, Amit Kumar Acharzo, Shams Anamika, Shamsunnahar Khushi, Bishwajit Bokshi
This study was designed to identify some bioactive phytochemicals from ethanolic extract of roots of Litsea polyantha and to evaluate some of its pharmacological activities. Phytochemical tests indicated the presence of reducing sugar, combined reducing sugar, tannins, flavonoids, alkaloids, terpenoids, and phenol. In the antioxidant assay using 2-diphenyl-1-picryl-hydrazyl (DPPH) free radical scavenging method, the IC50 value was found to be 82.31 μg/mL. Total content of phenolic compounds, flavonoid, and tannin was found to be 152...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29234365/ethnopharmacological-uses-phytochemistry-and-pharmacological-properties-of-croton-macrostachyus-hochst-ex-delile-a-comprehensive-review
#8
REVIEW
Alfred Maroyi
Croton macrostachyus is widely used as herbal medicine by the indigenous people of tropical Africa. The potential of C. macrostachyus as herbal medicine, the phytochemistry, and pharmacological properties of its parts used as herbal medicines are reviewed. The extensive literature survey revealed that C. macrostachyus is traditionally used to treat or manage at least 81 human and animal diseases and ailments. The species is used as herbal medicine for diseases and ailments such as abdominal pains, cancer, gastrointestinal disorders, malaria, pneumonia, sexually transmitted infections, skin infections, typhoid, and wounds and as ethnoveterinary medicine...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29233689/in-vitro-toxicity-evaluation-of-estragole-containing-preparations-derived-from-foeniculum-vulgare-mill-fennel-on-hepg2-cells
#9
Sara Levorato, Luca Dominici, Cristina Fatigoni, Claudia Zadra, Rita Pagiotti, Massimo Moretti, Milena Villarini
Estragole, a common component of herbs and spices, is a wellknown genotoxic hepatocarcinogen in rodents, whereas its potential toxic effect in humans is still debated. In the European contest, one of the major sources of human exposure to this phytochemical is Foeniculum vulgare Mill. (fennel). Therefore, the aim of this study was to evaluate the in vitro toxicity of estragole in the context of two complex phytochemical mixtures derived from fennel: fennel seed powder (FSPw) and fennel seed essential oil (FSEO)...
December 9, 2017: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29233039/characterization-antibacterial-total-antioxidant-scavenging-reducing-power-and-ion-chelating-activities-of-green-synthesized-silver-copper-and-titanium-dioxide-nanoparticles-using-artemisia-haussknechtii-leaf-extract
#10
Mehran Alavi, Naser Karimi
Recently, major problem related to pathogenic bacteria is augmentation of antibiotic resistance which has been changed treatment and recovery of millions of infectious patients. The present study reports an eco-friendly, rapid and easy method for synthesis of silver (Ag), copper (Cu) and titanium dioxide (TiO2) nanoparticles (NPs) using Artemisia haussknechtii leaf aqueous extract with antibacterial activities against multi-drug resistance (MDR) bacteria species. Three different concentrations (0.001, 0.01 and 0...
December 12, 2017: Artificial Cells, Nanomedicine, and Biotechnology
https://www.readbyqxmd.com/read/29232949/anti-oxidative-flavan-3-ol-dimers-from-the-leaves-of-camellia-fangchengensis
#11
Xiu-Hua Meng, Chang Liu, Rong Fan, Li-Fang Zhu, Shi-Xiong Yang, Hong-Tao Zhu, Dong Wang, Chong-Ren Yang, Ying-Jun Zhang
Camellia fangchengensis Liang et Zhong, belonging to the genus Camellia sect. Thea (Theaceae), is an endemic tea species to the south and southwest areas of Guangxi province, P. R. China. Known as a wild tea plant, the leaves have been used for producing green tea or black tea by the local people of its growing area. HPLC and LC-MS analysis showed the leaves contain oligomeric catechins as major phenolic components. Further detailed phytochemical study led to the identification of five flavan-3-ol dimers (1 ¬¬- 5) including two new ones, fangchengbisflavans A (1) and B (2) from the leaves of C...
December 12, 2017: Journal of Agricultural and Food Chemistry
https://www.readbyqxmd.com/read/29232753/solvent-extraction-and-gc-ms-analysis-of-sesame-seeds-for-determination-of-bioactive-antioxidant-fatty-acid-fatty-oil-components
#12
Abdul Qadir, Athar Ali, Muhammad Arif, Abdulmohsen H Al-Rohaimi, Satya Prakash Singh, Usama Ahmad, Mohd Khalid, Arun Kumar
The seed kernels of Sesamum indicum L. (family: Pedaliaceae) were extracted with ethanol and yield of components determined by Gas Chromatography/Mass Spectrometry (GC/MS). The free radical scavenging activities of ethanolic extract against1, 1-Diphenyl-2-picrylhydrazyl (DPPH) were determined by UV spectrophotometer at 517 nm. Phytochemical screening revealed the presence of numerous bioactive compounds including steroids, phenolic, terpenoids, fatty acids and different types of ester compounds. The ethanolic extract was purified and analyzed by GC MS...
December 12, 2017: Drug Research
https://www.readbyqxmd.com/read/29230630/phytochemical-study-and-evaluation-of-cytotoxicity-mutagenicity-cell-cycle-kinetics-and-gene-expression-of-bauhinia-holophylla-bong-steud-in-hepg2-cells-in-vitro
#13
Diego Luis Ribeiro, Heloísa Lizotti Cilião, Ana Flávia Leal Specian, Juliana Mara Serpeloni, Marcelo Tempesta De Oliveira, Eliana Aparecida Varanda, Wagner Vilegas, Luiz Leonardo Saldanha, Wilner Martínez-López, Anne Lígia Dokkedal, Ilce Mara Syllos Cólus
Bauhinia holophylla (Bong.) Steud. (Fabaceae) is a plant used in Brazilian folk medicine to treat diabetes and inflammation. This study evaluated the phytochemical properties, cytotoxic, apoptotic, mutagenic/antimutagenic effects and alterations in gene expression (RNAm) in HepG2 cells treated with the B. holophylla extract. The phytochemical profile highlight the presence of flavonoids isorhamentin and quercetin derivates. The MTT assay was used to evaluate the cytotoxicity of different concentrations for different treatment times...
December 11, 2017: Cytotechnology
https://www.readbyqxmd.com/read/29228818/evaluation-of-herbal-concoctions-sold-at-ga-maja-limpopo-province-in-south-africa-and-in-vitro-pharmacological-evaluation-of-plants-used-to-manufacture-the-concoctions
#14
Mash M Matotoka, Peter Masoko
The aim of the study was to evaluate the biological activities and safety of commercial herbal concoctions manufactured in Ga Maja (Limpopo province). Microbial contamination was evaluated by spread-plating the concoctions on agar plates. The VITEK 2 instrument was used for identification of the pure cultures. Nutritional content of the concoctions was determined. Thin layer chromatography was used to analyze the chemical constituents of the extracts. The microdilution assay and bioautography were used to evaluate antimicrobial activity against selected microorganisms...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29228808/variation-in-phytochemical-composition-reveals-distinct-divergence-of-aloe-vera-l-burm-f-from-other-aloe-species-rationale-behind-selective-preference-of-aloe-vera-in-nutritional-and-therapeutic-use
#15
Priyankar Dey, Somit Dutta, Anurag Chowdhury, Abhaya Prasad Das, Tapas Kumar Chaudhuri
In the present study, we have phytochemically characterized 5 different abundant Aloe species, including Aloe vera (L.) Burm.f., using silylation followed by Gas Chromatography-Mass Spectrometry technique and compared the data using multivariate statistical analysis. The results demonstrated clear distinction of the overall phytochemical profile of A vera, highlighted by its divergent spatial arrangement in the component plot. Lowest correlation of the phytochemical profiles were found between A vera and A aristata Haw...
January 1, 2017: Journal of Evidence-based Complementary & Alternative Medicine
https://www.readbyqxmd.com/read/29227656/artocarmins-g-m-prenylated-4-chromenones-from-the-stems-of-artocarpus-rigida-and-their-tyrosinase-inhibitory-activities
#16
Mai T T Nguyen, Tho H Le, Hai X Nguyen, Phu H Dang, Truong N V Do, Manabu Abe, Ryukichi Takagi, Nhan T Nguyen
Phytochemical analysis of an EtOAc extract of the stems of Artocarpus rigida led to the identification of seven new prenylated 4-chromenones, artocarmins G-M (1-7), and nine known compounds (8-17). Their structures were identified based on physical data analysis. In the tyrosinase inhibitory activity test, norartocarpetin (8) displayed the strongest effect, with an IC50 value of 0.023 μM.
December 11, 2017: Journal of Natural Products
https://www.readbyqxmd.com/read/29227542/characterization-of-peanut-oil-bodies-integral-proteins-lipids-and-their-associated-phytochemicals
#17
Farah Zaaboul, Husnain Raza, Cao Chen, Yuanfa Liu
A microscopic image of a section of a peanut seed shows that oil bodies (OBs) are a small droplet of oil that is dispersed throughout the whole seed. The protein profile of peanut's OBs recovered using the aqueous extraction method at different pH was found to have 2 oleosin isoforms of 14 and 16 kDa. Moreover, OBs essential amino acids are 1.52 higher than those in the PPI. Oleic acid and linoleic acid are the major fatty acids in both cold press peanut oil and OBs regardless of pH. Tocopherol content went from 270...
December 11, 2017: Journal of Food Science
https://www.readbyqxmd.com/read/29226147/antifungal-activity-of-aqueous-extracts-of-some-dominant-algerian-medicinal-plants
#18
Nasrine Salhi, Sultan Ayesh Mohammed Saghir, Valeria Terzi, Iman Brahmi, Naima Ghedairi, Samia Bissati
Aim: This study investigated the antifungal properties of aqueous extracts obtained from indigenous plants that grow spontaneously in the Northern Sahara of Algeria. The activities of these plants in controlling two fungal species that belong to Fusarium genus were evaluated in an in vitro assay. Materials and Methods: Fresh aerial parts of four plant species (Artemisia herba alba, Cotula cinerea, Asphodelus tenuifolius, and Euphorbia guyoniana) were collected for the preparation of aqueous extracts...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29225112/fisetin-a-bioactive-phytochemical-with-potential-for-cancer-prevention-and-pharmacotherapy
#19
REVIEW
Dharambir Kashyap, Ajay Sharma, Katrin Sak, Hardeep Singh Tuli, Harpal Singh Buttar, Anupam Bishayee
A wide variety of chronic diseases, such as neurodegenerative and cardiovascular disorders, diabetes mellitus, osteoarthtitis, obesity and various cancers, are now being treated with cost effective phytomedicines. Since synthetic medicines are very expensive, concerted efforts are being made in developing and poor countries to discover cost effective medicines for the treatment of non-communicable diseases (NCDs). Understanding the underlying mechanisms of bioactive medicines from natural sources would not only open incipient avenues for the scientific community and pharmaceutical industry to discover new drug molecules for the therapy of NCDs, but also help to garner knowledge for alternative therapeutic approaches for the management of chronic diseases...
December 7, 2017: Life Sciences
https://www.readbyqxmd.com/read/29224253/phytochemical-composition-and-biological-activities-of-dyssodia-tagetiflora-lag
#20
Ana María García-Bores, Amira Arciniegas-Arciniegas, Alma Reyna Campos, Carlos Céspedes-Acuña, Betsaida Avila-Suárez, Julio Alarcón-Enos, Saul Flores-Maya, Adriana Montserrat Espinosa-González, Alfonso Romo de Vivar-Romo, Carlos Pérez Plasencia, José Guillermo Avila-Acevedo
While plants of the genus Dyssodia are used by man to a certain extent, few phytochemical and pharmacological studies have been performed with species of this genus. D. tagetiflora is an endemic plant of Mexico and has been used as fodder. The aim of this research was to isolate and identify the main bioactive components and evaluate the insecticidal, antioxidant, genotoxic and cytoprotective activities of D. tagetiflora. The isolated substances included an essential oil composed of six monoterpenes, and extracts containing two flavonols, three flavonol-glycosides and four thiophenes...
December 10, 2017: Chemistry & Biodiversity
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