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https://www.readbyqxmd.com/read/28108750/-titanium-or-steel-as-osteosynthesis-material-systematic-literature-search-for-clinical-evidence
#1
Alexander Joeris, Sabine Goldhahn, Elke Rometsch, Dankward Höntzsch
BACKGROUND: The selection of the appropriate implant material, stainless steel or titanium, is still the decision of the surgeon and/or the affiliated institution. Additionally, remarkable international differences can be found between the different markets, which cannot really be explained. OBJECTIVE: A systematic literature search was performed to verify whether there is clinical evidence for the preference of one material over the other. MATERIAL AND METHODS: The systematic literature search was performed utilizing the internet databases PubMed, Cochrane and Web of Science...
January 20, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28107267/the-prevalence-of-the-complications-and-their-associated-factors-in-humeral-lengthening-for-achondroplasia-retrospective-study-of-54-cases
#2
Natsuko Nakano-Matsuoka, Kenichi Fukiage, Yuki Harada, Naoya Kashiwagi, Tohru Futami
The aim of this study is to evaluate the complications of humeral lengthening and their associated factors. Fifty-four achondroplastic patients were treated by bilateral humeral lengthening. Our original shoulder sling was sufficient to prevent shoulder dislocation. Pre-existing radial head dislocation was observed in 18 patients. Lengthening was accomplished in all cases without a decrease in the elbow function. Seven humeri fractured after the fixator removal. The risk factors for postoperative fracture were a waiting period of less than 5 days, a healing index less than 25, and the concave shape of the callus...
January 19, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28106724/osteocalcin-mediates-biomineralization-during-osteogenic-maturation-in-human-mesenchymal-stromal-cells
#3
Yu-Tzu Tsao, Yi-Jeng Huang, Hao-Hsiang Wu, Yu-An Liu, Yi-Shiuan Liu, Oscar K Lee
There is a growing interest in cell therapies using mesenchymal stromal cells (MSCs) for repairing bone defects. MSCs have the ability to differentiate into osteoprogenitors and osteoblasts as well as to form calcified bone matrix. However, the molecular mechanisms governing mineralization during osteogenic differentiation remain unclear. Non-collagenous proteins in the extracellular matrix are believed to control different aspects of the mineralization. Since osteocalcin is the most abundant non-collagenous bone matrix protein, the purpose of this study is to investigate the roles of osteocalcin in mineral species production during osteogenesis of MSCs...
January 17, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28106673/outcomes-of-pediatric-fractures-managed-with-closed-reduction-by-orthopaedic-residents-in-the-emergency-department
#4
Vivek Natarajan, Ermias Abebe, James Dunlap, Patrick Bosch, Ozgur Dede, W Timothy Ward, James Roach
BACKGROUND: Closed reduction of pediatric fractures is commonly performed by orthopaedic residents using conscious sedation in the emergency department (ED). The purpose of this study was to determine the rate of satisfactory reductions as performed by residents, and to determine the outcomes of these procedures. METHODS: A retrospective review was performed of all fractures that underwent closed reduction under conscious sedation in the ED of a level 1 pediatric trauma center between January 1, 2010 and November 30, 2014...
January 18, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28105502/transfracture-medial-transposition-of-the-radial-nerve-associated-with-plate-fixation-of-the-humerus
#5
Ali Hassan Chamseddine, Amer Abdallah, Hadi Zein, Assad Taha
PURPOSE: The aim of this study was to illustrate safety, feasibility and advantages of transfracture medial transposition of the radial nerve during the lateral approach and lateral plating of humeral fractures located in the mid and distal shaft. METHODS: This was a retrospective review and analysis of medical records and radiographs of 19 patients who underwent a transfracture medial transposition of the radial nerve. Fifteen patients were treated for fresh fracture and four for nonunion...
January 19, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28105092/serum-n-terminal-telopeptide-of-type-i-collagen-as-an-early-marker-of-fracture-nonunion-in-rabbits
#6
Jian-Ping Lin, Zhan-Jun Shi, Ning-Jiang Shen, Jian Wang, Zao-Min Li, Jun Xiao
The aim of the present study was to establish an experimental animal model of fracture nonunion, and to investigate the changes in serum biomarker concentrations in fracture nonunion. A total of 20 purebred New Zealand rabbits were divided into two group: A bone defect group and a bone fracture group. In the bone defect group, a 15-mm section of bone (including the periosteum) was removed from the mid-radius, and the medullary cavities were closed with bone wax. In the bone fracture group, the mid-radius was fractured...
December 2016: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28102170/complication-of-a-femoral-fracture-treated-by-intramedullary-nailing-numerical-analysis-of-a-clinical-case
#7
Jakub J Słowiński, Konrad Kudłacik
The aim of this paper is to conduct a numerical analysis of a case of femoral fracture treated by intramedullary nailing and confirm the conditions which led to the formation of a pseudarthrosis at the fracture site. A low-energy femoral fracture was treated by placing a ChFN System intramedullary nail with a derotation pin. Using the finite element method, a bone-implant system was generated which made it possible to observe the displacement area and strains in the region of the fracture gap. The calculations were conducted for 3 variants of the model, using a titanium nail (10 mm and 12 mm) and a steel one (10 mm)...
August 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28102166/stress-fractures-of-tibia-treated-with-ilizarov-external-fixator
#8
Radosław Górski, Sławomir Żarek, Piotr Modzelewski, Ryszard Górski, Paweł Małdyk
BACKGROUND: Stress fractures are the result of cyclic loading of the bone, which gradually becomes damaged. Most often they are treated by rest or plaster cast and, in rare cases, by internal fixation. There is little published data on initial reposition followed by stabilization with the Ilizarov apparatus in such fractures. MATERIAL AND METHODS: Six patients were treated with an external fixator according to the Ilizarov method for a stress fracture of the tibia between 2007 and 2015...
August 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28102162/biomechanical-causes-of-fracture-non-union-after-diaphyseal-forearm-fracture-fixation-an-in-silico-analysis-case-study
#9
Jacek Lorkowski, Tomasz Kuczek, Ireneusz Kotela
: Non-union of forearm bone shaft fractures remains, in some cases, a major clinical problem. The aim of this study was to assess the biomechanical causes of non-union in a patient with diaphyseal forearm fractures fixated with LCP plates. The paper describes the case of a 35-year-old male who developed a non-union as a result of destabilisation of the fixation. The case was analysed with an in silico analysis of the removed fixation device. CONCLUSION: To sum up, we believe that the case described in this paper confirms the limitations to the use of LCP reconstruction plates in patients with well-developed musculature, even in the case of repeat fixation, when good adjustment of the plate well to the axis of the bone appears necessary...
October 28, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28101590/-minimally-invasive-treatment-of-intra-articular-calcaneal-fractures-with-the-2%C3%A2-point-distractor
#10
G Mattiassich, W Litzlbauer, M Ponschab, R Ortmaier, C Rodemund
OBJECTIVE: Open treatment of calcaneus fractures often has an increased risk of wound healing. Minimally invasive treatment with small incisions reduces complications. INDICATIONS: Calcaneal fractures with malalignment/comminution >1-2 mm; broadening, varus alignment of the calcaneal length axis or shortening; emergency surgery for open fractures or compartment syndrome. CONTRAINDICATIONS: Local or general contraindications. SURGICAL TECHNIQUE: Standardised positioning; restoration of length/axis with 2‑point distractor under fluoroscopic control...
January 18, 2017: Operative Orthopädie und Traumatologie
https://www.readbyqxmd.com/read/28100942/potential-benefits-of-rib-fracture-fixation-in-patients-with-flail-chest-and-multiple-non-flail-rib-fractures
#11
Meiguang Qiu, Zhanjun Shi, Jun Xiao, Xuming Zhang, Shishui Ling, Hao Ling
The purpose of this study is to evaluate the potential benefits of rib fracture fixation in patients with flail chest and multiple non-flail rib fractures versus conventional treatment modalities. A retrospective reviewed study compared 86 cases which received surgical treatment between June 2009 and May 2013 to 76 cases which received conservative treatment between January 2006 and May 2009. The patients were divided into the flail chest (n = 38) and multiple non-flail rib fracture groups (n = 124)...
December 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/28100253/minimally-invasive-percutaneous-osteosynthesis-versus-orif-for-sanders-type-ii-and-iii-calcaneal-fractures-a-prospective-randomized-intervention-trial
#12
Cong Jin, Dong Weng, Wanlei Yang, Wei He, Wengqing Liang, Yu Qian
BACKGROUND: This randomized controlled trial compared the clinical outcomes and complications of a novel minimally invasive percutaneous osteosynthesis (MIPO) with those of conventional treatment via an extended L-shaped lateral approach for calcaneal fractures. METHODS: Sixty-four patients with displaced intraarticular calcaneal fractures were enrolled. The patients were randomly allocated to receive either MIPO (29 patients) or open reduction and internal fixation via an extended L-shaped lateral approach (35 patients)...
January 18, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28100234/arthroscopic-reduction-and-fixation-of-coronoid-fractures-with-an-exchange-rod-a-new-technique
#13
Kan Ouyang, Daping Wang, Wei Lu, Jianyi Xiong, Jian Xu, Liangquan Peng, Haifeng Liu, Hao Li, Wenzhe Feng
BACKGROUND: The ulnar coronoid process plays a central role in maintaining elbow stability. Some of its fractures were often combined with injury of bone and ligament. Arthroscopy enables perfect visualization to allow anatomical repair. METHODS: From January 2012 to December 2013, six patients (four males, two females) with a mean age of 26.6 years were treated. The left and right ulnas were involved in two and four patients, respectively. All patients suffered from ipsilateral subluxation of the elbow without associated radial fracture...
January 18, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28099300/plate-fixation-compared-with-nonoperative-treatment-for-displaced-midshaft-clavicular-fractures-a-multicenter-randomized-controlled-trial
#14
Sarah Woltz, Sylvia A Stegeman, Pieta Krijnen, Bart A van Dijkman, Tom P H van Thiel, Niels W L Schep, Piet A R de Rijcke, Jan Paul M Frölke, Inger B Schipper
BACKGROUND: The use of operative treatment for clavicular fractures is increasing, despite varying results in previous studies. The aim of this study was to compare plate fixation and nonoperative treatment for displaced midshaft clavicular fractures with respect to nonunion, adverse events, and shoulder function. METHODS: In this multicenter, prospective, randomized controlled trial, patients between 18 and 60 years old with a displaced midshaft clavicular fracture were randomized between nonoperative treatment and open reduction with internal plate fixation...
January 18, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28098876/bdnf-regulates-the-expression-and-secretion-of-vegf-from-osteoblasts-via-the-trkb-erk1-2-signaling-pathway-during-fracture-healing
#15
Zitao Zhang, Yan Zhang, Zhengnan Zhou, Hongfei Shi, Xusheng Qiu, Jin Xiong, Yixin Chen
Brain‑derived neurotrophic factor (BDNF), a member of the neurotropic family, is expressed in osteoblast‑like cells of a fracture callus, however, its role in fracture healing remains to be fully elucidated. Osteoblasts isolated from Sprague Dawley rats were stimulated by BDNF in a dose‑ and time‑dependent manner. Immunoblotting and immunofluorescence was used to detect the expression and distribution of targeted proteins. The concentration of vascular endothelial growth factor (VEGF) released in medium was determined using an ELISA...
January 12, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28097402/-mechanobiology-of-fracture-healing
#16
EDITORIAL
L Claes
No abstract text is available yet for this article.
January 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28097252/enterococcus-faecalis-causing-delayed-spondylodiscitis-in-a-case-with-retained-intraspinal-bullet
#17
Siddharth N Aiyer, Ajoy Prasad Shetty, Rishi Kanna, Srikanth Reddy, Shanmuganathan Rajasekaran
Delayed presentations have been reported following gunshot wounds (GSW) with retained intraspinal bullets due to migration of projectile or lead intoxication. We report on the rare occurrence of delayed pyogenic spondylodiscitis and neurological dysfunction following injury from low velocity GSW to the spine with a retained projectile. A 55-year-old male presented 4 months following GSW to the abdomen which resulted in colonic injury and L5 fracture. The patient was treated initially with ileo-transverse anastomosis, antibiotics, without retrieval of the bullet...
December 2016: Journal of Spine Surgery (Hong Kong)
https://www.readbyqxmd.com/read/28096214/cartilage-to-bone-transformation-during-fracture-healing-is-coordinated-by-the-invading-vasculature-and-induction-of-the-core-pluripotency-genes
#18
Diane P Hu, Federico Ferro, Frank Yang, Aaron J Taylor, Wenhan Chang, Theodore Miclau, Ralph S Marcucio, Chelsea S Bahney
Fractures heal predominantly through the process of endochondral ossification. The classic model of endochondral ossification holds that chondrocytes mature to hypertrophy, undergo apoptosis and new bone forms by invading osteoprogenitors. However, recent data demonstrate that chondrocytes transdifferentiate to osteoblasts in the growth plate and during regeneration, yet the mechanism(s) regulating this process remain unknown. Here, we show a spatially-dependent phenotypic overlap between hypertrophic chondrocytes and osteoblasts at the chondro-osseous border in the fracture callus, in a region we define as the transition zone (TZ)...
January 15, 2017: Development
https://www.readbyqxmd.com/read/28095672/targeted-self-healing-by-magnetically-guiding-microcapsules
#19
Matthew D Crall, Michael W Keller
Magnetically guided microcapsules are used to achieve self-healing with of the healing components required using traditional self-healing approaches. Microcapsules are rendered responsive to magnetic fields by suspending magnetic nanoparticles in the core material. The nanoparticles are surface-modified to enable urea-formaldehyde encapsulation within a phenyl acetate core. Magnetic fields are used to guide the microcapsules to the expected fracture location in tapered double-cantilever beam (TDCB) epoxy specimens...
January 17, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28094687/successful-management-of-femoral-trauma-in-a-through-knee-amputee-with-a-previous-malunited-fracture-implications-and-functional-outcome
#20
Beth Lineham, Paul Harwood, Peter Giannoudis
BACKGROUND: After amputation patients are more likely to injure their residual limb. An injury of a previously amputated limb, especially if the residuum is not anatomically normal, poses a dilemma for management. Case Description and Methods: This case report discusses a femoral fracture sustained proximal to a through-knee amputation. Findings and outcomes: The fracture was at the site of a malunited fracture. A shortening osteotomy with bone graft was undertaken to improve alignment and prosthetic fit and remove poor-quality bone...
January 1, 2017: Prosthetics and Orthotics International
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