keyword
MENU ▼
Read by QxMD icon Read
search

Fracture + healing

keyword
https://www.readbyqxmd.com/read/29667926/proximal-tibia-stress-fracture-with-osteoarthritis-of-knee-radiological-and-functional-analysis-of-one-stage-tka-with-long-stem
#1
Dhanasekaran Soundarrajan, Natesan Rajkumar, Palanisamy Dhanasekararaja, Shanmuganathan Rajasekaran
INTRODUCTION: Proximal tibia stress fractures with knee osteoarthritis pose a challenging situation. We evaluated the radiological and functional outcome of one-stage total knee arthroplasty (TKA) and long stem for patients with varied grades of knee arthritis and proximal tibia stress fractures.  Methods: We analysed 20 patients from April 2012 to March 2017 with proximal tibia stress fractures associated with knee osteoarthritis of varied grades. Out of 20 patients, five were acute fresh fractures...
2018: SICOT-J
https://www.readbyqxmd.com/read/29667005/the-bmp-2-mutant-l51p-a-bmp-receptor-ia-binding-deficient-inhibitor-of-noggin
#2
REVIEW
Hany Mohamed Khattab, Satoshi Kubota, Masaharu Takigawa, Takuo Kuboki, Walter Sebald
The antagonist-specific regulation in tissue engineering constitutes important attempts to achieve an improved and rapid bone regeneration by controlling the natural biological response of the natural body growth factors. L51P is molecularly engineered bone morphogentic protein-2 (BMP-2) variant with a substitution of the 51st leucine with a proline residue. L51P is deficient in BMP receptor binding, but maintains its structure and affinity for inhibitory proteins such as noggin, chordin, and gremlin. These modifications convert the BMP-2 variant L51P into a receptor-inactive inhibitor of BMP antagonists...
April 17, 2018: Journal of Bone and Mineral Metabolism
https://www.readbyqxmd.com/read/29664881/tibial-fracture-nonunion-and-time-to-healing-following-reamed-intramedullary-nailing-risk-factors-based-on-a-single-centre-review-of-1003-patients
#3
Hannah L Dailey, Katherine A Wu, Ping-Shi Wu, Margaret M McQueen, Charles M Court-Brown
OBJECTIVE: To determine factors associated with nonunion of adult tibial fractures. DESIGN: Retrospective review with data collection for logistic regression and survival analysis. SETTING: Scottish Level I trauma centre, 1985 to 2007. PATIENTS: During this period, 1,590 adult tibial fractures were treated by reamed nailing and 1,003 met all inclusion criteria for the chosen analysis. INTERVENTION: Reamed intramedullary nailing...
April 3, 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29664878/c2-translaminar-screw-fixation-in-children
#4
Brian W Yang, Michael P Glotzbecker, Michael Troy, Mark R Proctor, Michael T Hresko, Daniel J Hedequist
BACKGROUND: Axis (C2) screw fixation has been shown to be effective in treating disorders that necessitate cervical stabilization. Although translaminar C2 screws have demonstrated clinical efficacy in adults, this technique has not yet been thoroughly investigated in children. This study describes the indications, technique, and results of translaminar C2 screw fixation in a case series of pediatric cervical spine disorders. METHODS: We searched the orthopaedic database at our institution for patients who had undergone a cervical spinal fusion that encompassed C2 between 2007 and 2017...
April 16, 2018: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/29664851/minimally-displaced-isolated-radial-head-and-neck-fractures-do-not-require-formal-physical-therapy-results-of-a-prospective-randomized-trial
#5
Kenneth A Egol, Jack M Haglin, Ariana Lott, Nina Fisher, Sanjit R Konda
BACKGROUND: Nondisplaced and minimally displaced fractures of the radial head and neck are common injuries, yet the role of physical therapy (PT) in their treatment is unclear. The aim of this trial was to assess the need for formal PT following a simple fracture of the radial head or neck. METHODS: Patients who had a nondisplaced or minimally displaced fracture of the radial head or neck and presented to 1 of 2 providers were enrolled prospectively between January 2014 and August 2016...
April 18, 2018: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/29664803/posterior-shoulder-dislocation-associated-with-the-head-splitting-and-humeral-neck-fracture-impact-of-understanding-radiologic-signs-and-experience-with-an-extended-deltopectoral-approach
#6
Kemal Gokkus, Ergin Sagtas, Hasan Kara, Ahmet T Aydin
In this paper, our main objective was to emphasize the competency of extended deltopectoral exposure, enforced with the supraspinatus and subscapularis detachment, to gain access to the entire head. The second important point in this paper was to underline the importance of the knowledge that is necessary for interpreting classic radiologic signs of posterior fracture-dislocation of the shoulder. A 47-year-old woman fell down directly onto her shoulder while she was skiing. She was diagnosed with posterior shoulder dislocation, associated with fracture of the head (head splitting) and humeral neck fracture, with the aid of plain radiographs and computed tomographic results...
April 11, 2018: Techniques in Hand & Upper Extremity Surgery
https://www.readbyqxmd.com/read/29663560/activation-of-hedgehog-signaling-by-systemic-agonist-improves-fracture-healing-in-aged-mice
#7
Jennifer A McKenzie, Clayton Maschhoff, Xiaochen Liu, Nicole Migotsky, Matthew J Silva, Michael J Gardner
Fracture healing is a complex process of many coordinated biological pathways. This system can go awry resulting in nonunion, which leads to significant patient morbidity. The Hedgehog (Hh) signaling pathway is upregulated in fracture healing. We hypothesized that the Hh signaling pathway can be pharmacologically modulated to positively affect fracture healing. Diaphyseal femur fractures were created in elderly mice (18 months, C57BL/6 females), which have a blunted and delayed healing response compared to younger mice, and were stabilized with intramedullary pins...
April 16, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29663104/treatment-goals-for-distal-radius-fractures-in-2018-recommendations-and-practical-advice
#8
REVIEW
F Loisel, M Bourgeois, T Rondot, J Nallet, M Boeckstins, S Rochet, G Leclerc, L Obert, D Lepage
The goals of distal radius fracture treatment in patients above 65 years of age would not change over time if the fracture were the only factor to consider. However, people change, and fixation methods also change. Since this fracture heals in nearly every case and volar plates have eliminated the worry of malunion, we are left with two main goals. In active patients with weakened bones, the aim is to help them regain their quality of life as quickly as possible while avoiding iatrogenic conditions. This compromise is possible because of new tools-but at what price?...
April 16, 2018: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/29662775/relationship-between-heterotopic-ossification-and-traumatic-brain-injury-why-severe-traumatic-brain-injury-increases-the-risk-of-heterotopic-ossification
#9
REVIEW
Huan Huang, Wen-Xiang Cheng, Yi-Ping Hu, Jian-Hai Chen, Zheng-Tan Zheng, Peng Zhang
Heterotopic ossification (HO) is a pathological phenomenon in which ectopic lamellar bone forms in soft tissues. HO involves many predisposing factors, including congenital and postnatal factors. Postnatal HO is usually induced by fracture, burn, neurological damage (brain injury and spinal cord injury) and joint replacement. Recent studies have found that patients who suffered from bone fracture combined with severe traumatic brain injury (S-TBI) are at a significantly increased risk for HO occurrence. Thus, considerable research focused on the influence of S-TBI on fracture healing and bone formation, as well as on the changes in various osteogenic factors with S-TBI occurrence...
January 2018: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662755/cyr61-an-angiogenic-biomarker-to-early-predict-the-impaired-healing-in-diaphyseal-tibial-fractures
#10
Sabir Ali, Ajai Singh, Abbas Ali Mahdi, Rajeshwar Nath Srivastava
Background: Angiogenesis is a prerequisite for fracture repair, whereas insufficient blood supply is likely to result in impaired healing. In the present study, we aimed to determine the correlation of simple tibial fracture healing outcome with serial estimation of CYR61 expressions in the early phase of healing. Methods: In total, 107 adult fractured patients and 97 healthy controls were analysed. Peripheral blood samples were taken from controls (at once) and fractured patients at 4th , 7th , 10th , 15th , 20th and 28th days of post-fracture follow-ups to quantify the CYR61 mRNA and protein expression by qRT-PCR and Western blotting assay, respectively...
July 2017: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29662754/magnesium-based-implants-beyond-fixators
#11
Xiaodan Chen
The mystery behind magnesium-induced bone formation is revealed by linking the neuropeptide(s) from sensory nerves with the osteogenic differentiation of stem cells in the periosteum. Zhang and colleagues' study sheds light on the development of magnesium pills or calcitonin gene-related peptide-delivery system for the prevention or treatment of osteoporosis. The translational potential of this article: For the first time, magnesium is shown to be beneficial for fracture healing at the weight-bearing site...
July 2017: Journal of Orthopaedic Translation
https://www.readbyqxmd.com/read/29661673/the-use-of-pediatric-flexible-intramedullary-nails-for-minimally-invasive-fibular-fracture-fixation
#12
James C Connors, Mark A Hardy, Duane J Ehredt, Michael A Coyer
Fibular fractures in the setting of an unstable ankle joint require surgical fixation; however, several factors contradict open surgical correction. Severe soft tissue compromise can delay adequate fracture reduction and preclude the standard incisional approach. The soft tissue envelope in the setting of obesity, diabetes, and/or peripheral vascular disease further complicates definitive treatment. Poorly timed open fixation can lead to delayed healing of the incision site, with wound breakdown and the potential for hardware failure...
April 13, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29661672/development-and-validation-of-the-foot-union-scoring-evaluation-tool-for-arthrodesis-of-foot-structures
#13
Timothy A Karthas, Jeremy J Cook, Michael R Matthews, Michael L Sganga, Daniel D Hansen, Byron Collier, Philip Basile, Emily A Cook
Reliable evaluation of osseous consolidation after pedal arthrodesis can be difficult, and the presence or absence of radiographic healing often dictates care. Plain radiographs remain the mainstay imaging tool owing to their cost, efficiency, and low radiation exposure. Applying radiographic parameters that can reliably determine osseous healing is essential. However, currently, no reliable or validated measures are available to determine osseous union of any joint in the foot or ankle. The purpose of the present study was to develop a radiographic healing scoring system that would enhance the diagnostic healing assessment after joint arthrodesis of the foot or ankle...
April 13, 2018: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/29661112/osteoporotic-effect-on-bone-repair-in-lumbar-vertebral-body-defects-in-a-rat-model
#14
Munehiro Sakata, Hitoshi Tonomura, Tomonori Itsuji, Hidenobu Ishibashi, Ryota Takatori, Yasuo Mikami, Masateru Nagae, Ken Ichi Matsuda, Masaki Tanaka, Toshikazu Kubo
INTRODUCTION: The number of patients who suffered from osteoporotic vertebral fractures is increasing. Osteoporosis has been reported to affect the healing process using long bone models. However, few studies have reported using vertebrae. In this study, we created a bone defect in the anterior part of vertebral body in ovariectomized rat and evaluated the healing process. METHODS: Fifty-six 12-week old Sprague Dawley rats were divided into ovariectomy (OVX) and sham operation groups...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29660737/treatment-of-a-paediatric-distal-femoral-malunion-deformity
#15
Greta S Pavarotti, Randy J Boudrieau
OBJECTIVE:  The aim of this article was to describe the surgical re-alignment technique and stabilization of a distal femoral deformity in a 6-week-old, male, Foxhound. METHODS:  A healing metaphyseal fracture, resulting in a valgus deformity with internal rotation, was observed just proximal to the distal femoral physis. The deformity was treated by an opening wedge osteotomy with lateral translation and external rotation of the distal epiphysis using a guide-wire technique; a corticocancellous allograft bridged the defect, which was stabilized with a 2...
April 16, 2018: Veterinary and Comparative Orthopaedics and Traumatology: V.C.O.T
https://www.readbyqxmd.com/read/29659378/osteoimmunology-effects-of-standard-orthopaedic-interventions-on-inflammatory-response-and-early-fracture-healing
#16
Prism S Schneider, Emilie Sandman, Paul A Martineau
Achieving fracture union is highly dependent on the initial inflammatory phase of fracture healing, which is influenced by both the local and systemic inflammatory environments. The rapidly emerging field of osteoimmunology involves the study of the interactions between the immune system and the skeletal system. Recent research has advanced the current state of knowledge regarding the effects of the surrounding soft-tissue injury, fracture hematoma, and the method of fracture fixation on the inflammatory phase of fracture healing...
April 13, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29658523/determination-of-electrophysical-and-structural-properties-of-human-cancellous-bone-and-synthetic-bone-substitute-material-using-impedance-spectroscopy-and-x-ray-powder-diffraction
#17
Yvonne Haba, Martin Köckerling, Christoph Schick, Wolfram Mittelmeier, Rainer Bader
Electrophysical stimulation is used to support fracture healing and bone regeneration. For design optimization of electrostimulative implants, in combination with applied human donor bone or synthetic bone scaffolds, the knowledge of electrophysical properties is fundamental. Hence further investigations of the structural properties of native and synthetic bone is of high interest to improve biofunctionality of bone scaffolds and subsequent healing of the bone defect. The investigation of these properties was taken as an objective of this study...
2018: Acta of Bioengineering and Biomechanics
https://www.readbyqxmd.com/read/29657443/healing-of-femoral-fractures-by-the-meaning-of-an-innovative-intramedullary-nail
#18
V Filardi
In this paper, an innovative design of nail, conceived to heal fractures of long bones has been investigated. Its functioning is based essentially on sliding of conical surfaces located in a spindle and in a series of holding pins radially disposed around it. Spindle and holding pins are connected together by means of a sleeve. Medial and distal screws are not necessary. Rotational and longitudinal motions of the spindle are transformed in a radial expansion of the holding pins by the sliding of conical surfaces...
March 2018: Journal of Orthopaedics
https://www.readbyqxmd.com/read/29657401/end-threaded-intramedullary-positive-profile-screw-ended-self-tapping-pin-admit-pin-a-cost-effective-novel-implant-for-fixing-canine-long-bone-fractures
#19
Mitin Chanana, Adarsh Kumar, Som Prakash Tyagi, Amit Kumar Singla, Arvind Sharma, Uiase Bin Farooq
Aim: The current study was undertaken to evaluate the clinical efficacy of end-threaded intramedullary pinning for management of various long bone fractures in canines. Materials and Methods: This study was conducted in two phases, managing 25 client-owned dogs presented with different fractures. The technique of application of end-threaded intramedullary pinning in long bone fractures was initially standardized in 6 clinical patients presented with long bone fractures...
February 2018: Veterinary World
https://www.readbyqxmd.com/read/29657237/management-of-sternal-dislocation-with-and-without-surgery-in-cats-owner-assessed-long-term-follow-up-of-two-clinical-cases
#20
Gab-Chol Choi, Md Mahbubur Rahman, Hwangmin Kim, Sehoon Kim, In-Seong Jeong
The aim of this paper is to report two cases of sternal dislocation (SD) in cats and the long-term outcomes with and without surgery. In a cat with poly-traumatized SD (Case 1), mandibular, radial, and ulnar fractures were corrected first, and the SD was allowed to heal without intervention for 14 months. However, normal healing did not occur and sternal instability remained. Therefore, the SD was corrected surgically, and the cat recovered fully within 4 weeks. In a cat with isolated SD (Case 2), surgery was performed, and normal posture and gait were regained after 5 weeks...
April 16, 2018: Journal of Veterinary Medical Science
keyword
keyword
109391
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"