Read by QxMD icon Read


Shuping Zhang, Yinhai Su, Kuan Ding, Shuguang Zhu, Houlei Zhang, Xinzhi Liu, Yuanquan Xiong
The objective of this study was to evaluate the effect of inorganic species on torrefaction process and product properties. Torrefaction process of raw and leached rice husk was performed at different temperatures between 210 and 270 °C. Inorganic species have significant effect on the torrefaction process and properties of torrefaction products. The results indicated that solid yield increased, gas yield decreased and liquid yield remained unchanged for leached rice husk when compared to raw rice husk. Gas products from torrefaction process mainly contained CO2 and CO, and leaching process slightly reduced the volume concentration of CO2 ...
June 20, 2018: Bioresource Technology
E Ventura, A Futuro, S C Pinho, M F Almeida, J M Dias
The recovery of electronic waste to obtain secondary raw materials is a subject of high relevance in the context of circular economy. Accordingly, the present work relies on the evaluation of mining separation/concentration techniques (comminution, size screening, magnetic separation and gravity concentration) alone as well as combined with thermal pre-treatment to recover gold and copper from Waste Printed Circuit Boards. For that purpose, Waste Printed Circuit Boards were subjected to physical processing (comminution, size screening in 6 classes from <0...
June 20, 2018: Journal of Environmental Management
Rui Dong, Ziyue Zhu, Changchuan Yin, Rong L He, Stephen S-T Yau
Analyzing phylogenetic relationships using mathematical methods has always been of importance in bioinformatics. Quantitative research may interpret the raw biological data in a precise way. Multiple Sequence Alignment (MSA) is used frequently to analyze biological evolutions, but is very time-consuming. When the scale of data is large, alignment methods cannot finish calculation in reasonable time. Therefore, we present a new method using moments of cumulative Fourier power spectrum in clustering the DNA sequences...
June 20, 2018: Gene
Ana Simões, Francisco Veiga, Carla Vitorino, Ana Figueiras
The pharmaceutical industry has entered in a new era, as there is a growing interest in increasing the quality standards of dosage forms, through the implementation of more structured development and manufacturing approaches. For many decades, the manufacturing of drug products was controlled by a regulatory framework to guarantee the quality of the final product through a fixed process and exhaustive testing. Limitations related to the Quality by Test (QbT) system have been widely acknowledged. The emergence of Quality by Design (QbD) as a systematic and risk-based approach introduced a new quality concept based on a good understanding of how raw materials and process parameters influence the final quality profile...
June 20, 2018: Journal of Pharmaceutical Sciences
Sun-Goo Hwang, Kyung-Hee Kim, Byung-Moo Lee, Jun-Cheol Moon
The root plays an important role during plant development and growth, i.e., the plant body maintenance, nutrient storage, absorption of water, oxygen and nutrient from the soil, and storage of water and carbohydrates, etc. The objective of this study was attempted to determine root-specific genes at the initial developmental stages of maize by using network-based transcriptome analysis. The raw data obtained using RNA-seq were filtered for quality control of the reads with the FASTQC tool, and the filtered reads were pre-proceed using the TRIMMOMATIC tool...
July 2018: Genes & Genomics
Nils Tippkötter, Sophie Möhring, Jasmine Roth, Helene Wulfhorst
In comparison to crude oil, biorefinery raw materials are challenging in concerns of transport and storage. The plant raw materials are more voluminous, so that shredding and compacting usually are necessary before transport. These mechanical processes can have a negative influence on the subsequent biotechnological processing and shelf life of the raw materials. Various approaches and their effects on renewable raw materials are shown. In addition, aspects of decentralized pretreatment steps are discussed...
June 23, 2018: Advances in Biochemical Engineering/biotechnology
Arif Harmanci, Mark Gerstein
Functional genomics experiments, such as RNA-seq, provide non-individual specific information about gene expression under different conditions such as disease and normal. There is great desire to share these data. However, privacy concerns often preclude sharing of the raw reads. To enable safe sharing, aggregated summaries such as read-depth signal profiles and levels of gene expression are used. Projects such as GTEx and ENCODE share these because they ostensibly do not leak much identifying information. Here, we attempt to quantify the validity of this statement, measuring the leakage of genomic deletions from signal profiles...
June 22, 2018: Nature Communications
Noémi László, Katalin Lányi, Péter Laczay
The aim of our study was to examine the degradation of veterinary antibiotics in milk during boiling. Raw cow milk samples were fortified with the target compounds and boiled for various short time-intervals prevailing in household practice. Antibiotic concentrations were determined by LC-MS/MS measurements. Degradation rate constants, half-lives and degradation percentages were calculated. Cefoperazone and cloxacillin proved to be the less and the most heat-stable substance, with 78.3% and 9.6% degradation in 300 s respectively...
November 30, 2018: Food Chemistry
Ricardo N Alves, Ana L Maulvault, Vera L Barbosa, Margarita Fernandez-Tejedor, Alice Tediosi, Michiel Kotterman, Fredericus H M van den Heuvel, Johan Robbens, José O Fernandes, Rie Romme Rasmussen, Jens J Sloth, António Marques
The oral bioaccessibility of several essential and toxic elements was investigated in raw and cooked commercially available seafood species from European markets. Bioaccessibility varied between seafood species and elements. Methylmercury bioaccessibility varied between 10 (octopus) and 60% (monkfish). Arsenic (>64%) was the toxic element showing the highest bioaccessibility. Concerning essential elements bioaccessibility in raw seafood, selenium (73%) and iodine (71%) revealed the highest percentages. The bioaccessibility of elements in steamed products increased or decreased according to species...
November 30, 2018: Food Chemistry
Elisabeth G Biesta-Peters, Ida Jongenburger, Enne de Boer, Wilma F Jacobs-Reitsma
During the last decade Campylobacter has been the most commonly reported gastrointestinal bacterial infection in humans in the European Union. The use of a sensitive detection method based on enrichment of Campylobacter spp. is often needed when examining foods. However, as background flora developed resistance to third generation β-lactams used in selective culture media, the ISO method was adapted. It now consists of three different procedures (A, B, and C) depending on the expected concentration and condition of Campylobacter and the background microflora...
June 19, 2018: International Journal of Food Microbiology
Anming Yang, Song Zeng, Lu Yu, Ming He, Yuanyou Yang, Xiaozhen Zhao, Chaolin Jiang, Deyu Hu, Baoan Song
Dendrobium nobile (D. nobile) is a valuable Chinese herbal medicine. The discovery of microbial resources from has provided a wealth of raw materials. Stalk rot, which is caused by Pestalotiopsis, is one of the most serious diseases of D nobile and has resulted in serious losses in production. However, an effective method for the prevention and control of stalk rot remains lacking. In this study, we aimed to identify a biocontrol strain against Pestalotiopsis. We isolated Paenibacillus polymyxa Y-1, an endophytic bacterium, from the stem of D...
May 2018: Pesticide Biochemistry and Physiology
Jin-Qian Yu, Xiao-Wei Sun, Zhi-Wei Wang, Lei Fang, Xiao Wang
One new quinolinic scandine-type monoterpeniod alkaloid, 3-oxo-scandine (1), as well as seven known ones (2-8), was isolated from the roots of Melodinus henryi. Their structures were elucidated by extensive spectroscopic analysis. All of the compounds were prepared and evaluated for their anti-inflammatory activities by measuring the inhibitory activity of nitric oxide (NO) in vitro in RAW 264.7 mouse peritoneal macrophages. Compounds 6 and 7 showed significant activities with IC50 values of 8.54 and 5.19 μM, respectively...
June 22, 2018: Journal of Asian Natural Products Research
Shuai Wang, Qing-Qing Li, Fan Wang, Tao Yi, Ji-Fen Zhang
To study the intestinal absorption characteristics of drug's nanocrystalline self-stabilizing Pickering emulsion (NSSPE) in situ in rats. Rat single-pass intestinal perfusion model was established, and high performance liquid chromatography (HPLC) was used to detect the concentration of puerarin in rat intestinal perfusion solution, assay the absorption rate constant (Ka) and the intestinal apparent permeability coefficient (Papp) of NSSPE in duodenum, jejunum, ileum, and colon, which were compared with those of raw material, nanocrystal and normal emulsion, respectively...
May 2018: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
Gail A Wasserman, Xinhua Liu, Faruque Parvez, Yu Chen, Pam Factor-Litvak, Nancy J LoIacono, Diane Levy, Hasan Shahriar, Mohammed Nasir Uddin, Tariqul Islam, Angela Lomax, Roheeni Saxena, Elizabeth A Gibson, Marianthi-Anna Kioumourtzoglou, Olgica Balac, Tiffany Sanchez, Jennie K Kline, David Santiago, Tyler Ellis, Alexander van Geen, Joseph H Graziano
BACKGROUND: Exposure to inorganic arsenic (As) from drinking water is associated with modest deficits in intellectual function in young children; it is unclear whether deficits occur during adolescence, when key brain functions are more fully developed. OBJECTIVES: We sought to determine the degree to which As exposure is associated with adolescent intelligence, and the contributory roles of lead, cadmium, manganese and selenium. METHODS: We recruited a cross-section of 726 14-16 year olds (mean age = 14...
June 19, 2018: Environment International
Manuel Merlos, Enrique Portillo-Salido, Alex Brenchat, Bertrand Aubel, Jordi Buxens, Angels Fisas, Xavier Codony, Luz Romero, Daniel Zamanillo, José Miguel Vela
Drug combination for the treatment of pain is common clinical practice. Co-crystal of Tramadol-Celecoxib (CTC) consists of two active pharmaceutical ingredients (APIs), namely the atypical opioid tramadol and the preferential cyclooxygenase-2 inhibitor celecoxib, at a 1:1 molecular ratio. In this study, a non-formulated 'raw' form of CTC administered in suspension (referred to as ctcsusp ) was compared with both tramadol and celecoxib alone in a rat plantar incision postoperative pain model. For comparison, the strong opioids morphine and oxycodone, and a tramadol plus acetaminophen combination at a molecular ratio of 1:17 were also tested...
June 19, 2018: European Journal of Pharmacology
Marcello Nicoletti, Claudio Frezza, Lamberto Tomassini, Mauro Serafini, Armandodoriano Bianco
Painting and body art are increasing their utilisation as well as their cultural impact, since piercing and tattoos are expanding social phenomena, involving many young people. However, the utilised materials often enter the market with insufficient control and several cases of skin damages are reported. Safety of the utilised products must be ensured by adequate quality controls which must be easily made, rapid, low cost, clear and persuasive. The method here reported, regards the analysis on the possible presence of picramic acid in the ethyl acetate extracts of commercial henné powders by NMR Spectroscopy...
June 22, 2018: Natural Product Research
Young Hye Seo, Ju-Hyun Jeon, Miran Jeong, Seung Mok Ryu, Won Kyung Jeon, Dae Sik Jang, Sang Hee Shim, Dongho Lee, Jung-Hye Choi, Jun Lee
Apios americana is an important food crop producing edible tubers with high nutritional and medicinal values and is widely cultivated in many countries. Despite its usefulness, research on its secondary metabolites and biological activities has been limited. In the present study, a new coumaronochromone, (2 R,3 S)-3,7,4'-trihydroxy-5-methoxycoumaronochromone (1), and two new isoflavone glucosides, 7,2',4'-trihydroxy-5-methoxyisoflavone-4'- O-β-d-glucopyranoside (3) and 5,7,4'-trihydroxyisoflavone-7- O-β-d-gentiotrioside (5), were isolated from the tubers of A...
June 22, 2018: Journal of Natural Products
Claire Mayer-Laigle, Rova Karine Rajaonarivony, Nicolas Blanc, Xavier Rouau
Lignocellulosic feedstocks present a growing interest in many industrial processes as they are an ecological alternative to petroleum-based products. Generally, the size of plant raw materials needs to be reduced by milling step(s), to increase density, facilitate transport and storage, and to increase reactivity. However, this unit operation can prove to be important in term of investments, functioning costs, and energy consumption if the process is not fully adapted to the histological structure of the plant material, possibly challenging the profitability of the whole chain of the biomass conversion...
June 22, 2018: Bioengineering
Stefano Manfredini, Carlo Contini
Louse infestation is one of the oldest contagious pestilential diseases of humankind, which has recently re-emerged in several developing countries as well as in homeless individuals and migrants. The present work provides the first phase of an historical excursus of louse remedies based on the classics of pharmaceutical literature, codes, pharmacopoeia and treatises. The second phase involves a literature search, based on the principal medical databases (SciFinder, Pubmed, Google Scholar, ISI-Web of Science and Scopus), to match ancient raw materials and active principles for the treatment of pediculosis and their possible applications, with other current infectious pathologies transmitted by different carriers...
June 1, 2018: Le Infezioni in Medicina
Jing Huang, Hongyuan Chen, Chanyi Li, Wuping Liu, Wenjie Ma, Wen Rui
Radix Astragali is a famous traditional Chinese medicine and honey-processed Astragalus is a product of Radix Astragali acquired by honey-processing. These two products are widely utilized to treat various diseases. In this study, we screened bioactive components and metabolites of raw and honey-processed Astragalus in rat urine by ultra-performance liquid chromatography equipped with electrospray ionization/quadrupole time-of-flight mass spectrometry (UHPLC/ESI-Q-TOF-MS) combined with multivariate statistical analysis...
June 21, 2018: Journal of the American Society for Mass Spectrometry
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"