keyword
MENU ▼
Read by QxMD icon Read
search

Raw

keyword
https://www.readbyqxmd.com/read/29031060/an-insight-into-the-biological-activities-of-heterocyclic-fatty-acid-hybrid-molecules
#1
REVIEW
Vijayendar Venepally, Ram Chandra Reddy Jala
Heterocyclic compounds are the interesting core structures for the development of new bioactive compounds. Fatty acids are derived from renewable raw materials and exhibit various biological activities. Several researchers are amalgamating these two bioactive components to yield bioactive hybrid molecules with some desirable features. Heterocyclic-fatty acid hybrid derivatives are a new class of heterocyclic compounds with a broad range of biological activities and significance in the field of medicinal chemistry...
October 3, 2017: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29029368/who-accesses-surgery-at-district-level-in-sub-saharan-africa-evidence-from-malawi-and-zambia
#2
Jakub Gajewski, Rachel Dharamshi, Michael Strader, John Kachimba, Eric Borgstein, Gerald Mwapasa, Mweene Cheelo, Tracey McCauley, Leon Bijlmakers, Ruairi Brugha
OBJECTIVES: To examine age and gender distribution for the most common types of surgery in Malawi and Zambia. METHODS: Data were collected from major operating theatres in 8 district hospitals in Malawi and 9 in Zambia. Raw data on surgical procedures were coded by specialist surgeons for frequency analyses. RESULTS: In Malawi, female surgical patients had a mean age of 25 years, with 91% aged 16-40 years. Females accounted for 85%, and obstetric cases for 75%, of all surgical patients...
October 13, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/29028892/nephele-a-cloud-platform-for-simplified-standardized-and-reproducible-microbiome-data-analysis
#3
Nick Weber, David Liou, Jennifer Dommer, Philip MacMenamin, Mariam Quiñones, Ian Misner, Andrew Oler, Joe Wan, Lewis Kim, Meghan Coakley McCarthy, Samuel Ezeji, Karlynn Noble, Darrell E Hurt
Motivation: Widespread interest in the study of the microbiome has resulted in data proliferation and the development of powerful computational tools. However, many scientific researchers lack the time, training, or infrastructure to work with large datasets or to install and use command line tools. Results: The National Institute of Allergy and Infectious Diseases (NIAID) has created Nephele, a cloud-based microbiome data analysis platform with standardized pipelines and a simple web interface for transforming raw data into biological insights...
September 28, 2017: Bioinformatics
https://www.readbyqxmd.com/read/29028444/development-and-in-house-validation-of-a-real-time-polymerase-chain-reaction-for-the-detection-of-listeria-monocytogenes-in-meat
#4
Camilo Reyes, Luciano H Linares, Fabiana Moredo, Juan P Lirón, Victoria Brusa, Alejandra Londero, Lucía Galli, Juan M Oteiza, Magdalena Costa, Gerardo A Leotta
Listeriosis is a foodborne disease caused by Listeria monocytogenes. The aims of this work were to develop and validate an in-house real-time polymerase chain reaction (RT-PCR) for the detection of L. monocytogenes, and to determine its prevalence in raw ground beef samples from 53 butcheries that also sell ready-to-eat foods. One set of primers and one hydrolysis probe were designed for hly gene detection and then challenged with pure strains. The detection was successful for all L. monocytogenes strains analyzed and negative for all non-L...
October 13, 2017: Foodborne Pathogens and Disease
https://www.readbyqxmd.com/read/29028416/differences-in-risky-sexual-behavior-according-to-sexual-orientation-in-korean-adolescents
#5
Ji-Su Kim, Kyunghee Kim, Yeunhee Kwak
Adolescents in sexual minority groups are known to be at risk of contracting sexually transmitted diseases through risky sexual behavior. However, few studies have examined associations between sexual orientation and risky sexual behavior and sexually transmitted diseases in Korean adolescents. Therefore, this cross-sectional study used raw data from the Tenth Korea Youth Risk Behavior Web-Based Survey to explore these relationships. Logistic regression analyses were performed to examine the associations between risky sexual behavior and sexual orientation in adolescents...
October 13, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/29027933/dpph-radical-scavenging-and-postprandial-hyperglycemia-inhibition-activities-and-flavonoid-composition-analysis-of-hawk-tea-by-uplc-dad-and-uplc-q-tof-ms-e
#6
Xuan Xiao, Lijia Xu, Huagang Hu, Yinjun Yang, Xinyao Zhang, Yong Peng, Peigen Xiao
Hawk tea (Litsea coreana Lévl. var. Lanuginosa (Migo) Yen C. Yang & P.H. Huang), a very popular herbal tea material, has attracted more and more attention due to its high antioxidant properties and possible therapeutic effect on type II diabetes mellitus. The raw materials of Hawk tea are usually divided into three kinds: bud tea (BT), primary leaf tea (PLT) and mature leaf tea (MLT). In this study, the DPPH radical scavenging activity and the antimicrobial properties of these three kinds of Hawk tea from different regions were comparatively investigated, and a ultra-high performance liquid chromatographic coupled with a photodiode array detector (UPLC-DAD) method was employed for comparison of the three major flavonoid constituents, including hyperoside, isoquercitrin and astragalin, in different samples of Hawk tea...
October 13, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/29027509/multiply-adjusted-comparisons-a-meta-analysis-method-to-compare-single-arm-clinical-trial-data-to-literature-results-regarding-a-competitor
#7
Dietmar Boethig, Hartmut Hecker
Prospective randomized controlled trials are difficult to obtain if a promising new therapy has to be tested against seemingly obsolete alternatives. One method to address this problem is to compare the results of (multicentre) trials to literature results. However, previous treatment-era changes and population-dependent results complicate objective comparisons. The presented approach describes a method to objectify such comparisons in cases in which individual raw data regarding a new therapy have to be compared to summary results regarding a conventional alternative published in the literature...
January 1, 2017: Statistical Methods in Medical Research
https://www.readbyqxmd.com/read/29027457/gravimetric-standard-gas-mixtures-for-global-monitoring-of-atmospheric-sf6
#8
Jeong Sik Lim, Jinbok Lee, Dongmin Moon, Jin Seog Kim, Jeongsoon Lee, Bradley D Hall
In this study, standard gas mixtures of SF6 in synthetic air were gravimetrically developed as a suite consisting of 6 mixtures with mole fractions of SF6 ranging from 5 to 15 pmol/mol. For precision in weighing the gas fills, an automatic weighing system coupled with a high sensitivity mass balance was used and a gravimetry precision of 3 mg (2σ) was achieved. Impurity profiles of the raw gases were determined by various analyzers. In particular, sub pmol/mol levels of SF6 in the matrix components (N2, O2, and Ar) were carefully measured, since the mole fraction of SF6 in the final step can be significantly biased by this trace amount of SF6 in the raw gases of the matrix components...
October 13, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29027426/-projection-of-potential-geographic-distribution-of-apocynum-venetum-under-climate-change-in-northern-china
#9
Hui-Feng Yang, Jiang-Hua Zheng, Xiao-Guang Jia, Xiao-Jin Li
Apocynum venetum belongs to apocynaceae and is a perennial medicinal plant, its stem is an important textile raw materials. The projection of potential geographic distribution of A. venetum has an important significance for the protection and sustainable utilization of the plant. This study was conducted to determine the potential geographic distribution of A. venetum and to project how climate change would affect its geographic distribution. The projection geographic distribution of A. venetum under current bioclimatic conditions in northern China was simulated using MaxEnt software based on species presence data at 44 locations and 19 bioclimatic parameters...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29027417/-primary-exploration-of-key-influential-factors-recognization-method-of-tanreqing-injection
#10
Wen-Long Li, Jian-Chao Pan, Dong-Sheng Xue, Shao-Yong Liu, Hai-Bin Qu
To recognize the key influential factors during the liquid preparation process of Tanreqing injection, the near infrared(NIR) spectra of the raw materials and the operating parameters of 24 batches of physical manufacturing were recorded as independent variables, and the total soluble solids contents and the light inspection acceptance rate of the final products were collected as dependent variables. The calibration models were developed using the partial least-square regression (PLSR) method, and the correlation coefficients between the independent variables and the dependent variables were calculated...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29027416/-application-of-quality-by-design-in-granulation-process-for-ginkgo-leaf-tablet-%C3%A2-%C3%AF-influence-and-control-of-raw-materials-quality-variation
#11
Xiang-Long Cui, Bing Xu, Jun-Wen Liu, Guo-Lin Shi, Xin-Yuan Shi, Yan-Jiang Qiao
Raw materials' quality variation could affect the quality consistency of product and the clinical efficacy. In this paper, the high shear wet granulation (HSWG) process of the ginkgo leaf tablet was taken as the research object. Ginkgo biloba extracts and excipients microcrystalline cellulose collected from various sources and batches were used to simulate raw materials' quality variation. Real-time torque was recorded to analyze the viscosity of the wetting mass, and then by combining with physical fingerprint, the impact of physical quality variation of powders on granule properties could be investigated...
March 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29027240/low-dose-ct-reconstruction-using-spatially-encoded-nonlocal-penalty
#12
Kyungsang Kim, Georges El Fakhri, Quanzheng Li
PURPOSE: Computed tomography (CT) is one of the most used imaging modalities for imaging both symptomatic and asymptomatic patients. However, because of the high demand for lower radiation dose during CT scans, the reconstructed image can suffer from noise and artifacts due to the trade-off between the image quality and the radiation dose. The purpose of this paper is to improve the image quality of quarter dose images and to select the best hyperparameters using the regular dose image as ground truth...
October 2017: Medical Physics
https://www.readbyqxmd.com/read/29026636/neck-abscess-due-to-salmonella-choleraesuis-case-study-and-literature-review
#13
Ryoji Sugimoto, Hirotaka Suzuki, Takahito Nei, Ayaka Tashiro, Yohei Washio, Kazunari Sonobe, Yuzo Nakamura, Nozomu Wakayama, Shunta Inai, Hidemasa Izumiya
Introduction. We herein describe a case with a neck abscess due to non-typhoidal Salmonella (NTS). NTS habitually reside in our environment and colonize all animals including mammals. Colonizations of pigs, chickens, cows and sheep are important because food poisoning episodes in human are often associated with meat. Extra-intestinal infection due to NTS has numerous presentations and complications, with aortic aneurysms being common. Case presentation. A 26-year-old Japanese male complaining of left-sided neck swelling was referred to our hospital for a suspected deep neck abscess...
August 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29025960/de-novo-assembly-of-a-new-solanum-pennellii-accession-using-nanopore-sequencing
#14
Maximilian Hw Schmidt, Alexander Vogel, Alisandra K Denton, Benjamin Istace, Alexandra Wormit, Henri van de Geest, Marie E Bolger, Saleh Alseekh, Janina Maß, Christian Pfaff, Ulrich Schurr, Roger T Chetelat, Florian Maumus, Jean-Marc Aury, Sergey Koren, Alisdair R Fernie, Daniel Zamir, Anthony Bolger, Bjoern Usadel
Updates in nanopore technology have made it possible to obtain gigabases of sequence data. Prior to this, nanopore sequencing technology was mainly used to analyze microbial samples. Here, we describe the generation of a comprehensive nanopore sequencing dataset with a median read length of 11,979 bp for a self-compatible accession of the wild tomato species Solanum pennellii. We describe the assembly of its genome to a contig N50 of 2.5 MB. The assembly pipeline comprised initial read correction with Canu and assembly with SMARTdenovo...
October 12, 2017: Plant Cell
https://www.readbyqxmd.com/read/29025019/differing-molecular-response-of-young-and-advanced-maternal-age-human-oocytes-to-ivm
#15
J M Reyes, E Silva, J L Chitwood, W B Schoolcraft, R L Krisher, P J Ross
STUDY QUESTION: What effect does maternal age have on the human oocyte's molecular response to in vitro oocyte maturation? SUMMARY ANSWER: Although polyadenylated transcript abundance is similar between young and advanced maternal age (AMA) germinal vesicle (GV) oocytes, metaphase II (MII) oocytes exhibit a divergent transcriptome resulting from a differential response to in vitro oocyte maturation. WHAT IS KNOWN ALREADY: Microarray studies considering maternal age or maturation stage have shown that either of these factors will affect oocyte polyadenylated transcript abundance in human oocytes...
September 15, 2017: Human Reproduction
https://www.readbyqxmd.com/read/29024064/physiological-and-health-related-response-of-broiler-chickens-fed-diets-containing-raw-full-fat-soya-bean-meal-supplemented-with-microbial-protease
#16
M M Erdaw, R A Perez-Maldonado, P A Iji
A 2 × 3 factorial study (protease: 0 or 1,5000 PROT/kg and raw full-fat soya bean meal [RSBM] replacing the commercial SBM at 0, 45 and 75 g/kg of diet) was conducted to examine the performance of broilers. Phytase (2000 FYT/kg) was uniformly added to each diet, each also replicated six times, with eight birds per replicate. Birds were raised in climate-controlled rooms using sawdust as the bedding material and offered starter, grower and finisher diets. Feed intake (FI) and body weight gain (BWG) were reduced (p < ...
October 10, 2017: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/29024040/metal-halide-perovskite-transistors-for-printed-electronics-challenges-and-opportunities
#17
REVIEW
Yen-Hung Lin, Pichaya Pattanasattayavong, Thomas D Anthopoulos
Following the unprecedented rise in photovoltaic power conversion efficiencies during the past five years, metal-halide perovskites (MHPs) have emerged as a new and highly promising class of solar-energy materials. Their extraordinary electrical and optical properties combined with the abundance of the raw materials, the simplicity of synthetic routes, and processing versatility make MHPs ideal for cost-efficient, large-volume manufacturing of a plethora of optoelectronic devices that span far beyond photovoltaics...
October 12, 2017: Advanced Materials
https://www.readbyqxmd.com/read/29023753/postharvest-monitoring-of-organic-potato-cv-anuschka-during-hot-air-drying-using-vis-nir-hyperspectral-imaging
#18
R Moscetti, B Sturm, S O J Crichton, W Amjad, R Massantini
BACKGROUND: The potential of hyperspectral imaging (500÷1010 nm) was evaluated for monitoring of the quality of potato slices (var. Anuschka) of 5-, 7- and 9-mm thicknesses subjected to air drying at 50 °C. The study investigated 3 different features selection methods for the prediction of dry basis moisture content and colour of potato slices using the partial least squares regression (PLS). RESULTS: The feature selection strategies tested include interval PLS regression (iPLS), and differences and ratios between raw reflectance values for each possible pair of wavelengths (R[λ1 ]-R[λ2 ] and R[λ1 ]:R[λ2 ], respectively)...
October 11, 2017: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/29023557/stard-2015-was-reproducible-in-a-large-set-of-studies-on-glaucoma
#19
Gianni Virgili, Manuele Michelessi, Alba Miele, Francesco Oddone, Giada Crescioli, Valeria Fameli, Ersilia Lucenteforte
AIM: To investigate the reproducibility of the updated Standards for the Reporting of Diagnostic Accuracy Studies tool (STARD 2015) in a set of 106 studies included in a Cochrane diagnostic test accuracy (DTA) systematic review of imaging tests for diagnosing manifest glaucoma. METHODS: One senior rater with DTA methodological and clinical expertise used STARD 2015 on all studies, and each of three raters with different training profiles assessed about a third of the studies...
2017: PloS One
https://www.readbyqxmd.com/read/29023401/effects-of-sorghum-malting-on-colour-major-classes-of-phenolics-and-individual-anthocyanins
#20
Ali Khoddami, Mohammad Mohammadrezaei, Thomas H Roberts
Sorghum (Sorghum bicolor) grain contains many health-promoting phytochemicals, including a broad range of phenolic compounds. Malting of cereal grains is known to increase the bioavailability of macro- and micronutrients. However, the detailed effects of malting on sorghum grain anthocyanins, a major class of phenolics that influence the taste and colour of sorghum-based foods, requires further investigation. Eight commercial sorghum hybrids harvested from three regions in eastern Australia were malted and analysed for colour, tannin content, total phenolic content (TPC), flavan-4-ols, total flavonoids, total anthocyanins and 3-deoxyanthocyanins...
October 12, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
keyword
keyword
109389
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"