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https://www.readbyqxmd.com/read/29926557/clinical-characteristics-of-false-positive-lymph-node-on-chest-ct-or-pet-ct-confirmed-by-endobronchial-ultrasound-guided-transbronchial-needle-aspiration-in-lung-cancer
#1
Jongmin Lee, Young Kyoon Kim, Ye Young Seo, Eun Kyoung Choi, Dong Soo Lee, Yeon Sil Kim, Sook Hee Hong, Jin Hyoung Kang, Kyo Young Lee, Jae Kil Park, Sook Whan Sung, Hyun Bin Kim, Mi Sun Park, Hyeon Woo Yim, Seung Joon Kim
BACKGROUND: Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is a standard procedure to evaluate suspicious lymph node involvement of lung cancer because computed tomography (CT) and ¹⁸F-fluorodeoxyglucose positron emission tomography-CT (PET-CT) have limitations in their sensitivity and specificity. There are a number of benign causes of false positive lymph node such as anthracosis or anthracofibrosis, pneumoconiosis, old or active tuberculosis, interstitial lung disease, and other infectious conditions including pneumonia...
June 19, 2018: Tuberculosis and Respiratory Diseases
https://www.readbyqxmd.com/read/29924386/successful-identification-of-anatomical-markers-and-placement-of-feeding-tubes-in-critically-ill-patients-via-camera-assisted-technology-with-real-time-video-guidance
#2
Paul E Wischmeyer, Michelle M McMoon, Nathan H Waldron, Elizabeth J Dye
BACKGROUND: Enteral feeding via feeding tube (FT) provides essential nutrition support to critically ill patients or those who cannot intake adequate nutrition via the oral route. Unfortunately, 1%-2% of FTs placed blindly at bedside enter the airway undetected (as confirmed by x-ray), where they could result in adverse events. Misplaced FTs can cause complications including pneumothorax, vocal cord injury, bronchopleural fistula, pneumonia, and death. X-ray is typically performed to confirm FT placement before feeding, but may delay nutrition intake, may not universally identify misplacement, and adds cost and radiation exposure...
June 20, 2018: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/29921240/modelling-invasive-group-a-streptococcal-disease-using-bioluminescence
#3
L E Lamb, X Zhi, F Alam, M Pyzio, C L Scudamore, S Wiles, S Sriskandan
BACKGROUND: The development of vaccines and evaluation of novel treatment strategies for invasive group A streptococcal (iGAS) disease requires suitable models of human infection that can be monitored longitudinally and are preferably non-invasive. Bio-photonic imaging provides an opportunity to reduce use of animals in infection modelling and refine the information that can be obtained, however the range of bioluminescent GAS strains available is limited. In this study we set out to develop bioluminescent iGAS strains for use in in vivo pneumonia and soft tissue disease models...
June 19, 2018: BMC Microbiology
https://www.readbyqxmd.com/read/29920152/selective-management-of-multiple-bronchopleural-fistulae-in-a-pediatric-patient-on-extracorporeal-membrane-oxygenation-a-multidisciplinary-approach
#4
Cory N Criss, Ryan Barbaro, Kristy Ann Bauman, Odetola Folafoluwa, Ranjith Vellody, Marcus D Jarboe
INTRODUCTION: This case highlights the successful utilization of a multidisciplinary approach to numerous bilateral bronchopleural fistulae (BPF) using minimally invasive techniques. In this study, we present a previously healthy 14-year-old male hospitalized with 2009 H1N1 influenza and methicillin-resistant Staphylococcus aureus coinfection complicated by severe acute respiratory distress syndrome and multifocal necrotizing pneumonia, with significant lung tissue damage requiring prolonged extracorporeal membrane oxygenation (ECMO) support...
June 19, 2018: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29905925/ceftazidime-avibactam-for-refractory-bacteremia-vertebral-diskitis-osteomyelitis-with-pre-vertebral-abscess-and-bilateral-psoas-pyomyositis-secondary-to-klebsiella-pneumoniae-carbapenemase-producing-bacteria-kpc
#5
Rafael De León-Borrás, Julio Álvarez-Cardona, Jorge A Vidal, Humberto M Guiot
A 36-year-old man was admitted to the intensive care unit due to diabetic ketoacidosis and pneumonia requiring mechanical ventilation. Three weeks after admission, he developed a refractory bacteremia with Klebsiella pneumoniae carbapenemase-producing bacteria (KPC). He remained febrile and with bacteremia for six weeks despite therapy with polymyxin B, carbapenems, and amikacin. Imaging studies looking for deep-seated infection revealed vertebral L1-L2 diskitis and osteomyelitis with pre-vertebral abscess and bilateral psoas pyomyositis that were not amenable for drainage...
June 2018: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/29904468/rapidly-progressing-lepidic-pulmonary-metastases-from-a-treated-poorly-differentiated-hepatocellular-carcinoma-demonstrating-new-pathologic-features-of-cholangiocarcinoma-a-potential-diagnostic-pitfall-that-may-mimic-pneumonia
#6
Partha Hota, Chandra Dass, Maruti Kumaran, Xiaofeng Zhao, Nirag Jhala, Scott Simpson
Although the lung is a common site for metastatic disease from extrathoracic malignancies, a pattern of lepidic growth of these metastases is considered rare. A 67-year-old man with a history of partial hepatectomy for hepatocellular carcinoma (HCC) presented to our hospital with dyspnea and a nonproductive cough. Chest radiographs and computed tomography imaging demonstrated consolidation in the right upper lobe and an ipsilateral pleural effusion. Findings were initially suspected to be secondary to infection, given the radiographic appearance and the rapid development from a normal computed tomography 3 months previously...
April 2018: Radiology Case Reports
https://www.readbyqxmd.com/read/29904039/an-unusual-cause-of-cauda-equina-syndrome-lumbar-epidural-venous-engorgement
#7
Husam A AlTahan, Roaa R Amer, Areej A Madani, Eman A Bakhsh
BACKGROUND Epidural venous plexus (EVP) engorgement occurs due to many conditions, so it can be easily misdiagnosed. This becomes problematic when the diagnosis requires prompt treatment for a good outcome, especially when it results in cauda equina syndrome (CES). We report a case of extensive iliocaval thrombosis leading to epidural venous plexus and ascending lumbar vein engorgement as an outcome of deep venous thrombosis (DVT) due to probable adverse effects of oral combined contraceptive pills (OCCP). CASE REPORT A 42-year-old woman presented to a rural medical facility with bilateral lower-limb swelling and skin darkening for 2 days...
June 15, 2018: American Journal of Case Reports
https://www.readbyqxmd.com/read/29902913/pulmonary-nodular-lymphoid-hyperplasia-with-mass-formation-clinicopathologic-characteristics-of-nine-cases-and-review-of-the-literature
#8
Jongmin Sim, Hyun Hee Koh, Sangjoon Choi, Jinah Chu, Tae Sung Kim, Hojoong Kim, Joungho Han
Background: Pulmonary nodular lymphoid hyperplasia (PNLH) is a non-neoplastic pulmonary lymphoid disorder that can be mistaken for malignancy on radiography. Herein, we present nine cases of PNLH, emphasizing clinicoradiological findings and histological features. Materials and Methods: We analyzed radiological and clinicopathological features from the electronic medical records of nine patients (eight females and one male) diagnosed with PNLH. IgG and IgG4 immunohistochemical staining was performed in three patients...
June 15, 2018: Journal of Pathology and Translational Medicine
https://www.readbyqxmd.com/read/29900554/lung-disease-associated-with-occupational-styrene-exposure
#9
Keith C Meyer, Basant Sharma, Brent Kaufmann, Amanda Kupper, Michael Hodgson
Despite reports of pulmonary toxicity due to styrene, guidelines on acceptable styrene exposure levels have been based on risk of cancer and central nervous system and liver toxicity and not on respiratory effects. Many reports have linked exposure to styrene vapor in occupational settings to various forms of non-malignant pulmonary disorders including bronchiolitis, hypersensitivity pneumonitis, and occupational asthma. We report two cases in which the same tasks performed in a single workplace resulted in exposure to styrene vapor with subsequent development of acute respiratory symptoms associated with impaired gas exchange and imaging and histopathologic findings consistent with bronchiolitis and organizing pneumonia...
June 13, 2018: American Journal of Industrial Medicine
https://www.readbyqxmd.com/read/29899785/association-between-posterior-reversible-encephalopathy-syndrome-and-mycoplasma-pneumoniae-infection
#10
Archana Ramgopal, Aravind Thavamani, Abdulla Ghori
Mycoplasma pneumoniae is a microbe known to affect numerous organ systems, and in particular, can cause neurological manifestations. We describe an otherwise healthy child who presented with acute onset intractable headache with magnetic resonance imaging (MRI) findings consistent with posterior reversible encephalopathy syndrome (PRES), a neurological manifestation that presents with headache, vision changes, altered mental status, or seizures. Our patient did not have any of the common etiologies for PRES reported but tested positive for acute M...
January 2018: Journal of Pediatric Neurosciences
https://www.readbyqxmd.com/read/29889260/pulmonary-infarction-right-upper-quadrant-pain-as-a-presenting-symptom-with-review-of-typical-computed-tomography-imaging-features
#11
Steven T Fosmire, Guy N Gibson, John C Copeland, Marcus S Maydew, Christian Eggers
The purpose of this case presentation is to discuss right upper quadrant pain as an atypical presenting symptom in pulmonary infarction and review the typical computed tomography (CT) imaging features of pulmonary infarction to improve diagnostic accuracy. Pulmonary infarction results from occlusion of distal arterial vasculature within the lung parenchyma leading to ischemia, hemorrhage, and ultimately necrosis. Patients with lung infarction typically present with pleuritic chest pain and may have associated signs or symptoms of pulmonary thromboembolism or deep vein thrombosis...
June 8, 2018: Military Medicine
https://www.readbyqxmd.com/read/29889049/controlled-graphene-encapsulation-a-nanoscale-shield-for-characterising-single-bacterial-cells-in-liquid
#12
Jiayao Li, Changxi Zheng, Boyin Liu, Tsengming Chou, Yeonuk Kim, Shi Qiu, Jian Li, Wenyi Yan, Jing Fu
High-resolution single-cell imaging in their native or near-native state has received considerable interest for decades. In this research, we present an innovative approach that can be employed to study both morphological and nano-mechanical properties of hydrated single bacterial cells. The proposed strategy is to encapsulate wet cells with monolayer graphene with a newly developed water membrane approach, followed by imaging with both electron microscopy (EM) and atomic force microscopy (AFM). A computational framework was developed to provide additional insights, with the detailed nanoindentation process on graphene modeled based on finite element method...
June 11, 2018: Nanotechnology
https://www.readbyqxmd.com/read/29887705/outcome-of-pancreaticoduodenectomy-at-low-volume-centre-in-tier-ii-city-of-india
#13
Kumar Vinchurkar, Vishwanath M Pattanshetti, Manoj Togale, Santosh Hazare, Varadraj Gokak
Currently, pancreaticoduodenectomy (PD) is considered a common and feasibly performed surgery for periampullary tumours, but it is still a high-risk surgical procedure with potential morbidity and mortality rates. Previously, it was emphasised for the need of high-volume centres to perform specialised surgery such as PD. The authors have made an attempt to know the relation between low-volume centre and outcomes of PD. The study was conducted in a Tier-II city referral hospital located in Karnataka, India. A total of 37 patients with suspected periampullary neoplasms underwent surgical exploration with curative intent over a period of 4 years, i...
June 2018: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29880545/prospective-observational-study-of-point-of-care-ultrasound-for-diagnosing-pneumonia
#14
Claire Lissaman, Panida Kanjanauptom, Cyril Ong, Mark Tessaro, Elliot Long, Adam O'Brien
OBJECTIVES: The clinical diagnosis of pneumonia lacks specificity and may lead to antibiotic overuse, whereas radiological diagnoses can lack sensitivity. Point-of-care lung ultrasound is an emerging diagnostic tool. There are limited prospective data, however, on the accuracy of sonologists in the paediatric emergency department setting. We aimed to test the diagnostic accuracy of lung ultrasound for pneumonia using chest radiograph (CR) as the reference standard. METHODS: This prospective observational cohort study in a paediatric emergency department enrolled children aged 1 month to <18 years, who had a CR ordered for possible pneumonia...
June 7, 2018: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/29877282/invasive-pulmonary-aspergillosis-in-the-epidural-space-in-a-patient-with-acute-myelogenous-leukemia-with-myelodysplasia-related-changes-a-case-study-and-literature-review-of-vertebral-aspergillosis-in-japan
#15
Ryohei Ono, Shuku Sato, Satomi Okada, Emiko Kanbe, Eri Tanaka, Yotaro Tamai
Vertebral aspergillosis is a rare infectious disease with a high mortality rate. We herein report a 70-year-old woman with acute myelogenous leukemia with myelodysplasia-related changes, nontuberculous mycobacteriosis, and bronchiectasis who presented with a fever and cough. Her clinical symptoms and laboratory test results suggested febrile neutropenia and pneumonia. However, her clinical course was further complicated by lower extremity weakness. Magnetic resonance imaging of the spine showed consolidation contiguously spreading toward the epidural space between the T4 and T5...
June 6, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29868638/endoscopic-electrochemotherapy-for-esophageal-cancer-a-phase-i-clinical-study
#16
Charlotte Egeland, Lene Baeksgaard, Helle Hjorth Johannesen, Johan Löfgren, Christina Caroline Plaschke, Lars Bo Svendsen, Julie Gehl, Michael Patrick Achiam
Background and study aims:  Esophageal cancer is on the rise in the western world and the disease has a poor 5-year survival prognosis below 20 %. Electrochemotherapy is a treatment where a chemotherapeutic drug is combined with locally applied electrical pulses, in order to increase the drug's cytotoxicity in malignant cells. This study presents the first results with electrochemotherapy treatment in esophageal cancer. Patients and methods:  In this first-in-human trial, six patients with advanced esophageal cancer were treated with electrochemotherapy using intravenous bleomycin...
June 2018: Endoscopy International Open
https://www.readbyqxmd.com/read/29850353/pulmonary-artery-pseudoaneurysm-a-rare-cause-of-fatal-massive-hemoptysis
#17
Himaja Koneru, Sreeja Biswas Roy, Monirul Islam, Hesham Abdelrazek, Debabrata Bandyopadhyay, Nikhil Madan, Pradnya D Patil, Tanmay S Panchabhai
Pulmonary artery pseudoaneurysm (PAPA), an uncommon complication of pyogenic bacterial and fungal infections and related septic emboli, is associated with high mortality. The pulmonary artery (PA) lacks an adventitial wall; therefore, repeated endovascular seeding of the PA with septic emboli creates saccular dilations that are more likely to rupture than systemic arterial aneurysms. The most common clinical presentation of PAPA is massive hemoptysis and resultant worsening hypoxemia. Computed tomography angiography is the preferred diagnostic modality for PAPA; typical imaging patterns include focal outpouchings of contrast adjacent to a branch of the PA following the same contrast density as the PA in all phases of the study...
2018: Case Reports in Pulmonology
https://www.readbyqxmd.com/read/29804068/systemic-scleroderma-related-interstitial-pneumonia-associated-with-borderline-pulmonary-arterial-hypertension
#18
Keishi Sugino, Takayuki Kabuki, Kazutoshi Shibuya, Sakae Homma
A 65-year-old woman with a 35-year history of limited cutaneous systemic scleroderma was admitted to our hospital complaining of a 3-month history of progressive dyspnoea on exertion. High-resolution CT images of the chest revealed diffuse reticular opacities and traction bronchiectasis predominantly in the bilateral lower lobes of the lung. Specimens obtained during video-assisted thoracic surgery were consistent with fibrocellular non-specific interstitial pneumonia and accompanied by accumulation of lymph follicles within areas of fibrosis...
May 26, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29783820/-efficacy-of-bronchoalveolar-lavage-and-its-influence-factors-in-the-treatment-of-mycoplasma-pneumoniae-pneumonia-with-atelectasis
#19
M Yang, D H Yang, X Yang, Y S Wang, L Wu, Z M Chen
Objective: To investigate the efficacy of bronchoalveolar lavage (BAL) and its influence factors in the treatment of Mycoplasma pneumoniae pneumonia (MPP) with atelectasis. Methods: A retrospective case control study was performed on hospitalized MPP patients with atelectasis and received BAL in the Department of Pulmonology, Children's Hospital Zhejiang University School of Medicine from January 1, 2015 to July 31, 2017. Fever relieved in 48 hours and chest imaging improved in one week after BAL were considered effective...
May 2, 2018: Zhonghua Er Ke za Zhi. Chinese Journal of Pediatrics
https://www.readbyqxmd.com/read/29776398/primary-bacterial-ventriculitis-in-adults-an-emergent-diagnosis-challenge-report-of-a-meningoccal-case-and-review-of-the-literature
#20
Anaïs Lesourd, Nicolas Magne, Anaïs Soares, Caroline Lemaitre, Muhamed-Kheir Taha, Isabelle Gueit, Michel Wolff, François Caron
BACKGROUND: Defined by an infection of the ventricular system of the brain, ventriculitis is usually known as a health-care associated infection. In contrast, primary pyogenic ventriculitis complicating community-acquired meningitis is uncommon, and mainly described in infants. Only seven cases that have occured in adults have been found in the international literature. CASE PRESENTATION: We report here a new case due to Neisseria meningitidis occurring in an 85 year-old-man...
May 18, 2018: BMC Infectious Diseases
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