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Imaging of pneumonia

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https://www.readbyqxmd.com/read/29686791/lung-consolidation-as-a-rare-presentation-of-lymphoplasmacytic-lymphoma-with-extramedullary-waldenstr%C3%A3-m-s-macroglobulinemia
#1
Omar Abdulfattah, Ebad Ur Rahman, Bikash Bhattarai, Sumit Dahal, Zainab Alnafoosi, David Trauber, Danilo Enriquez, Frances Schmidt
Objectives : Lymphoplasmacytic lymphoma (LPL) is a mature B cell lymphoma that usually involves the bone marrow, spleen and lymph nodes. Extramedullary involvement, including the lung, is rarely reported. Case description : A 73-year-old female initially presented to our hospital complaining of productive cough of white-colour sputum for three weeks duration. She reported unintentional weight loss of ten pounds over the last five months. There was no history of haemoptysis, fever, night sweats, chills, recent infections or hospitalization...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29683868/differentiating-usual-interstitial-pneumonia-from-nonspecific-interstitial-pneumonia-using-high-resolution-computed-tomography-the-straight-edge-sign
#2
Xi Zhan, Tilman Koelsch, Steven M Montner, Allen Zhu, Rekha Vij, Jeffery J Swigris, Jonathan H Chung
PURPOSE: The purpose of this article was to determine whether a novel finding on coronal computed tomography (CT) can help differentiate usual interstitial pneumonia (UIP) from nonspecific interstitial pneumonia (NSIP) in order to obviate lung biopsy. MATERIALS AND METHODS: Two chest radiologists, blinded to clinical data, reviewed 3 preselected coronal images from CT scans, performed within 1 year of surgical lung biopsy (SLB), from 51 patients with biopsy-proven UIP and 15 with biopsy-proven NSIP...
April 21, 2018: Journal of Thoracic Imaging
https://www.readbyqxmd.com/read/29682967/in-vivo-two-photon-fluorescence-imaging-of-the-activity-of-the-inflammatory-biomarker-lta4h-in-a-mouse-pneumonia-model
#3
Hui Wang, Ke Xue, Ping Li, Yuyun Yang, Zixu He, Wei Zhang, Wen Zhang, Bo Tang
Severe atmospheric haze caused by industrial pollution has severely affected human health and led to the increasing incidence of cardiopulmonary diseases, including pneumonia. Conventional methods for diagnosis of pneumonia are complicated and tedious, and current clinical imaging techniques might cause organ injuries to some extent. Therefore, an accurate, fast, and intact imaging method must be developed to diagnose pneumonia in the early stages. In this study, we propose a new two-photon fluorescence probe, named as ASPC, for detection of the activity of the inflammatory biomarker LTA4H through specific recognition and cleavage of amides containing the unnatural amino acid L-AspBzl...
April 23, 2018: Analytical Chemistry
https://www.readbyqxmd.com/read/29678166/why-does-my-patient-s-basilar-artery-continue-to-grow-a-four-year-case-study-of-a-patient-with-symptoms-of-vertebrobasilar-dolichoectasia
#4
Dao Pei Zhang, Yan Fang Peng, Qian Kun Ma, Min Zhao, Huai Liang Zhang, Suo Yin
BACKGROUND: Vertebrobasilar dolichoectasia (VBD) is a clinical entity associated with ischemic stroke, compression of cranial nerves or brainstem, and hydrocephalus. There have been relatively few studies following the progression of VBD in patients presenting with a variety of diverse clinical features. CASE PRESENTATION: Here, we report a case study of a male with progressive VBD who was followed from November 2012 to December 2016. The patient had diagnosed hypertension for several years and suffered from left peripheral facial paralysis, recurrent ischemic attacks in the brainstem and cerebellum, obstructive hydrocephalus and frequent pneumonia...
April 20, 2018: BMC Neurology
https://www.readbyqxmd.com/read/29671104/long-term-follow-up-in-patients-treated-by-stent-implantation-for-post-ablation-pulmonary-vein-stenosis
#5
Elisabeth Iversen, Erik J S Packer, Synne M Sandberg, Øyvind Bleie, Per Ivar Hoff, Peter Schuster
PURPOSE: Symptomatic severe pulmonary vein stenosis (PVS) after catheter ablation of atrial fibrillation (AF) is a rare but well-recognized complication. Treatment options include pulmonary vein angioplasty with or without drug eluting balloons or angioplasty with stent implantation. The treatment of choice is unclear. In our center, pulmonary vein stenting is the treatment of choice for significantly stenotic veins. We present the long-term clinical outcome of 9 patients treated with stent implantation...
April 18, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29658455/-efficacy-of-early-treatment-via-fiber-bronchoscope-in-children-with-mycoplasma-pneumoniae-pneumonia-complicated-by-airway-mucus-obstruction
#6
Li-Jie Cao, Jian-Hua Liu, Jin-Feng Shuai, Bo Niu, Su-Kun Lu, Kun-Ling Huang
OBJECTIVE: To study the efficacy of early treatment via fiber bronchoscope in children with Mycoplasma pneumoniae pneumonia (MPP) complicated by airway mucus obstruction. METHODS: According to the time from admission to the treatment via fiber bronchoscope, the children with MPP who were found to have airway mucus obstruction under a fiber bronchoscope were randomly divided into early intervention group (≤3 days; n=40) and late intervention group (>3 days; n=56)...
April 2018: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/29658199/the-added-value-of-the-lateral-chest-radiograph-for-diagnosing-community-acquired-pneumonia-in-the-pediatric-emergency-department
#7
Michalle Soudack, Semion Plotkin, Aviva Ben-Shlush, Lisa Raviv-Zilka, Jeffrey M Jacobson, Michael Benacon, Arie Augarten
BACKGROUND: Opinions differ as to the need of a lateral radiograph for diagnosing community acquired pneumonia in children referred to the emergency department. A lateral radiograph increases the ionizing radiation burden but at the same time may improve specificity and sensitivity in this population. OBJECTIVES: To determine the value of the frontal and lateral chest radiographs compared to frontal view stand-alone images for the management of children with suspected community acquired pneumonia seen in a pediatric emergency department...
January 2018: Israel Medical Association Journal: IMAJ
https://www.readbyqxmd.com/read/29650059/labyrinthitis-ossificans-in-a-cynomolgus-macaque-macaca-fascicularis
#8
Gayathriy Balamayooran, Hannah M Atkins, Christopher T Whitlow, Samuel T Aycock, Michael A Nader, J Mark Cline, David L Caudell
Labyrinthitis is inflammation of the membranous and bony labyrinth of the inner ear. Typical portals of entry includehematogenous spread from the cochlear vasculature, passage of otitis media pathogens through the round window, and mostcommonly, meningogenic spread from the subarachnoid space. The sequela of chronic inner ear inflammation is labyrinthitisossificans, in which inner ear structures are replaced by fibrous and osseous tissues. Labyrinthitis in humans has been reportedconcurrently with infection due to various viruses (for example, varicella-zoster, measles, mumps) and bacteria (for example,Treponema pallidum, Streptococcus pneumoniae) and may be associated with vertebrobasilar ischemia and meningitis...
April 12, 2018: Comparative Medicine
https://www.readbyqxmd.com/read/29628384/comprehensive-analysis-of-prognostic-factors-in-hospitalized-patients-with-pneumonia-occurring-outside-hospital-serum-albumin-is-not-less-important-than-pneumonia-severity-assessment-scale
#9
Hiroyuki Miyazaki, Nobuhiko Nagata, Takanori Akagi, Satoshi Takeda, Taishi Harada, Shinichiro Ushijima, Takashi Aoyama, Yuji Yoshida, Hiroshi Yatsugi, Masaki Fujita, Kentaro Watanabe
PURPOSE: This study aimed to elucidate factors related to 30-day mortality of pneumonia occurring outside hospital by comprehensively analyzing data considered relevant to prognosis. METHODS: Data considered relevant to prognosis were retrospectively examined from clinical charts and chest X-ray images of all patients with pneumonia occurring outside hospital admitted to our hospital from 2010 to 2016. The primary outcome was 30-day mortality. RESULTS: Data were collected from 534 patients (317 community-acquired pneumonia and 217 nursing- and healthcare associated pneumonia patients; 338 men (63...
April 5, 2018: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/29628299/effectiveness-and-safety-of-sclerotherapy-for-treatment-of-low-flow-vascular-malformations-of-the-oropharyngeal-region
#10
Patrick Bourgouin, Frédéric Thomas-Chaussé, Patrick Gilbert, Marie-France Giroux, Sébastien Périgny, Louis Guertin, Josée Dubois, Gilles Soulez
PURPOSE: To evaluate the efficacy and safety of sclerotherapy with sodium tetradecyl sulfate (STS) and bleomycin for treatment of venous malformations (VMs) of the oropharyngeal region. MATERIALS AND METHODS: A retrospective study of 33 patients with 46 VMs of the buccal and pharyngolaryngeal cavity associated with impairment of eating, respiration, or elocution was performed. Individual lesions were divided based on their anterior or posterior location, using the base of the tongue as an anatomic landmark...
April 6, 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29606857/the-reliability-of-lung-ultrasound-in-assessment-of-idiopathic-pulmonary-fibrosis
#11
REVIEW
Diana Manolescu, Lavinia Davidescu, Daniel Traila, Cristian Oancea, Voicu Tudorache
Idiopathic pulmonary fibrosis (IPF) is the severest form of idiopathic interstitial pneumonia, with a median survival time estimated at 2-5 years from the time of diagnosis. It occurs mainly in elderly adults, suggesting a strong link between the fibrosis process and aging. Although chest high-resolution computed tomography (HRCT) is currently the method of choice in IPF assessment, diagnostic imaging with typical usual interstitial pneumonia (UIP) provides definitive results in only 55%, requiring an invasive surgical procedure such as lung biopsy or cryobiopsy for the final diagnostic analysis...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29606668/rituximab-in-the-treatment-of-interstitial-lung-disease-associated-with-antisynthetase-syndrome-a-multicenter-retrospective-case-review
#12
Tracy J Doyle, Namrata Dhillon, Rachna Madan, Fernanda Cabral, Elaine A Fletcher, Diane C Koontz, Rohit Aggarwal, Juan C Osorio, Ivan O Rosas, Chester V Oddis, Paul F Dellaripa
OBJECTIVE: To assess clinical outcomes including imaging findings on computed tomography (CT), pulmonary function testing (PFT), and glucocorticoid (GC) use in patients with the antisynthetase syndrome (AS) and interstitial lung disease (ILD) treated with rituximab (RTX). METHODS: We retrospectively identified all patients at 2 institutions with AS-ILD who were treated with RTX. Baseline demographics, PFT, and chest CT were assessed before and after RTX. Two radiologists independently evaluated CT using a standardized scoring system...
April 1, 2018: Journal of Rheumatology
https://www.readbyqxmd.com/read/29603777/postoperative-survival-and-early-complications-after-intracranial-surgery-in-dogs
#13
Alexander K Forward, Holger A Volk, Steven De Decker
OBJECTIVE: To describe survival and early postoperative outcome after intracranial surgery in dogs. STUDY DESIGN: Retrospective case series. ANIMALS: Fifty client-owned dogs that underwent intracranial surgery. METHODS: Records were searched and analyzed for dogs that underwent intracranial surgery between 2005 and 2015. Signalment, clinical presentation, neurological deficits, concurrent medical conditions, laboratory data, diagnosis, administration of perioperative glucocorticoids or antiepileptic drugs, and specific imaging, surgical, and anesthetic variables were recorded...
March 30, 2018: Veterinary Surgery: VS
https://www.readbyqxmd.com/read/29602783/quantitative-imaging-flow-cytometry-of-legionella-infected-dictyostelium-reveals-the-impact-of-retrograde-trafficking-on-pathogen-vacuole-composition
#14
Amanda Welin, Stephen Weber, Hubert Hilbi
The ubiquitous environmental bacterium Legionella pneumophila survives and replicates within amoebae and human macrophages by forming a Legionella -containing vacuole (LCV). In an intricate process governed by the bacterial Icm/Dot type IV secretion system and a plethora of "effector proteins" the nascent LCV interferes with a number of intracellular trafficking pathways, including retrograde transport from endosomes to the Golgi apparatus. Conserved retrograde trafficking components such as the retromer coat complex or the phosphoinositide (PI) 5-phosphatase Dd5P4/OCRL restrict intracellular replication of L...
March 30, 2018: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/29600075/sarcopenia-is-a-predictor-of-outcomes-after-lobectomy
#15
James A Miller, Kassem Harris, Charles Roche, Samjot Dhillon, Athar Battoo, Todd Demmy, Chukwumere E Nwogu, Elisabeth U Dexter, Mark Hennon, Anthony Picone, Kristopher Attwood, Sai Yendamuri
Background: As screening for lung cancer rises, an increase in the diagnosis of early stage lung cancers is expected. Lobectomy remains the standard treatment, but there are alternatives, consideration of which requires an estimation of the risk of surgery. Sarcopenia, irrespective of body mass index, confers a worse prognosis in many groups of patients including those undergoing surgery. Here we examine the association of muscle mass with outcomes for patients undergoing lobectomy. Methods: Consecutive patients undergoing lobectomy were retrospectively reviewed...
January 2018: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/29599087/a-novel-method-for-strict-intranasal-delivery-of-non-replicating-rsv-vaccines-in-cotton-rats-and-non-human-primates
#16
Michael P Citron, Manishkumar Patel, Mona Purcell, Shu-An Lin, Daniel J Rubins, Paul McQuade, Cheryl Callahan, Alexa Gleason, Ioan Petrescu, Walter Knapp, Chinedu Orekie, Sai Chamarthy, Zhiyun Wen, Sinoeun Touch, Matthew Pine, Jane Fontenot, Cameron Douglas, Xiaoping Liang, Amy S Espeseth
Respiratory syncytial virus (RSV) is the most common viral cause of bronchiolitis and pneumonia in children twelve months of age or younger and a significant cause of lower respiratory disease in older adults. As various clinical and preclinical candidates advance, cotton rats (Sigmodon hispidus) and non-human primates (NHP) continue to play a valuable role in RSV vaccine development, since both animals are semi-permissive to human RSV (HRSV). However, appropriate utilization of the models is critical to avoid mis-interpretation of the preclinical findings...
March 26, 2018: Vaccine
https://www.readbyqxmd.com/read/29595008/-image-of-the-month-a-pediatric-case-of-necrotizing-pneumoniae
#17
M Saliba, F Lebrun, M Lewin, F Pierart, M Thimmesch
No abstract text is available yet for this article.
March 2018: Revue Médicale de Liège
https://www.readbyqxmd.com/read/29582318/clinical-mimics-an-emergency-medicine-focused-review-of-pneumonia-mimics
#18
REVIEW
Drew Alan Long, Brit Long, Alex Koyfman
Pneumonia is a common cause of morbidity and mortality in adults in the United States. While pneumonia classically presents with a fever, cough, and shortness of breath, the presentation can vary widely in adults. This review evaluates history and physical examination findings of pneumonia and several conditions that mimic pneumonia. Pneumonia is a potentially deadly disease. History and examination findings are variable in pneumonia, and many conditions mimic pneumonia. These conditions include pulmonary embolism, diffuse interstitial lung disease, endocarditis, vasculitis, diffuse alveolar hemorrhage, acute decompensated heart failure, tuberculosis, lung cancer, and acute respiratory distress syndrome...
March 26, 2018: Internal and Emergency Medicine
https://www.readbyqxmd.com/read/29580292/hermansky-pudlak-syndrome-type-2-manifests-with-fibrosing-lung-disease-early-in-childhood
#19
Meike Hengst, Lutz Naehrlich, Poornima Mahavadi, Joerg Grosse-Onnebrink, Suzanne Terheggen-Lagro, Lars Høsøien Skanke, Luise A Schuch, Frank Brasch, Andreas Guenther, Simone Reu, Julia Ley-Zaporozhan, Matthias Griese
BACKGROUND: Hermansky-Pudlak syndrome (HPS), a hereditary multisystem disorder with oculocutaneous albinism, may be caused by mutations in one of at least 10 separate genes. The HPS-2 subtype is distinguished by the presence of neutropenia and knowledge of its pulmonary phenotype in children is scarce. METHODS: Six children with genetically proven HPS-2 presented to the chILD-EU register between 2009 and 2017; the data were collected systematically and imaging studies were scored blinded...
March 27, 2018: Orphanet Journal of Rare Diseases
https://www.readbyqxmd.com/read/29577303/ct-findings-in-pneumocystis-carinii-pneumonia-in-five-dogs
#20
F Schiborra, C J Scudder, R M Littler, C R Lamb, J F McConnell, T W Maddox
Pneumocystis carinii pneumonia is a rare disease in dogs. It is primarily reported in cavalier King Charles spaniels and miniature dachshunds with suspected underlying immunodeficiency. This case series reports the findings in five dogs (four cavalier King Charles spaniels and one Bedlington terrier) with confirmed P. carinii pneumonia. Thoracic (CT) revealed ground glass opacity of the pulmonary parenchyma with a diffuse or multifocal distribution. The severity of this pattern was variable. Less consistent imaging findings included parenchymal bands, bronchial dilation and signs consistent with pulmonary hypertension...
March 25, 2018: Journal of Small Animal Practice
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