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Rectal cancer operative treatment versus nonoperative

Angelita Habr-Gama, Rodrigo Oliva Perez, Wladimir Nadalin, Jorge Sabbaga, Ulysses Ribeiro, Afonso Henrique Silva e Sousa, Fábio Guilherme Campos, Desidério Roberto Kiss, Joaquim Gama-Rodrigues
OBJECTIVE: Report overall long-term results of stage 0 rectal cancer following neoadjuvant chemoradiation and compare long-term results between operative and nonoperative treatment. METHODS: Two-hundred sixty-five patients with distal rectal adenocarcinoma considered resectable were treated by neoadjuvant chemoradiation (CRT) with 5-FU, Leucovorin and 5040 cGy. Patients with incomplete clinical response were referred to radical surgical resection. Patients with incomplete clinical response treated by surgery resulting in stage p0 were compared to patients with complete clinical response treated by nonoperative treatment...
October 2004: Annals of Surgery
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