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radiofrequency ablation colorectal liver

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https://www.readbyqxmd.com/read/29113650/laparoscopic-parenchymal-preserving-liver-resections-for-colorectal-liver-metastases-in-the-era-of-highly-effective-systemic-therapy-and-selective-internal-radiation-therapy-can-often-prevent-a-hemihepatectomy-with-video
#1
Mathieu D'Hondt, Frédéric Ververken, Frederiek Nuytens
BACKGROUND: Preservation of hepatic parenchyma is important in liver surgery to prevent postoperative liver failure and according to some reports it could offer a prolonged survival and lower recurrence rates compared to major hepatectomies in patients with colorectal liver metastases. However, laparoscopic parenchyma-preserving liver resections can be technically challenging. The aim of this video is to illustrate the concept of laparoscopic parenchymal-preserving liver resections after conversion chemotherapy with targeted therapy...
December 2017: Surgical Oncology
https://www.readbyqxmd.com/read/29063852/local-control-outcomes-using-stereotactic-body-radiation-therapy-for-liver-metastases-from-colorectal-cancer
#2
Ji Hyeon Joo, Jin-Hong Park, Jin Cheon Kim, Chang Sik Yu, Seok-Byung Lim, In Ja Park, Tae Won Kim, Yong Sang Hong, Kyu-Pyo Kim, Sang Min Yoon, Jongmoo Park, Jong Hoon Kim
PURPOSE: To evaluate the effective dose and patterns of recurrence after stereotactic body radiation therapy (SBRT) for hepatic metastases that arise from colorectal cancer. METHODS AND MATERIALS: A cohort of 70 patients with 103 colorectal liver metastases were treated with SBRT at a single institution. The prescribed doses were 45 to 60 Gy in 3 to 4 fractions, but these were modified according to the tolerance of the adjacent normal tissue. To allow for dose comparisons, a biological equivalent dose was calculated...
November 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29061837/immediate-and-long-term-results-of-radiofrequency-ablation-for-colorectal-liver-metastases
#3
Ciprian Cirimbei, Vlad Rotaru, Elena Chitoran, Oana Pavaleanu, Simona Elena Cirimbei
BACKGROUND/AIM: Radiofrequency ablation (RFA) of colorectal liver metastases (CRLMs) is a method developed in the last 15 years. It provides an acceptable control of the malignant process with lower risks compared to surgical resection. The aim of the study was to assess immediate and long-term results, including recurrence, survival, morbidity/mortality rates after RFA. PATIENTS AND METHODS: Sixty-two cases with CRLMs were treated by RFA during open surgery (89 lesions)...
November 2017: Anticancer Research
https://www.readbyqxmd.com/read/29029986/radiofrequency-ablation-for-colorectal-cancer-liver-metastases-initially-greater-than-25%C3%A2-mm-but-downsized-by-neo-adjuvant-chemotherapy-is-associated-with-increased-rate-of-local-tumor-progression
#4
Léonor Benhaim, Mostafa El Hajjam, Robert Malafosse, Jacques Sellier, Catherine Julie, Alain Beauchet, Bernard Nordlinger, Frédérique Peschaud
BACKGROUND: Radiofrequency ablation (RFA) is a valid treatment for liver metastases from colorectal cancer (CRLM) smaller than 25 mm and unsuitable for surgical resection. Tumor size is predictive for local tumor progression (LTP). The aim of this study was to evaluate whether RFA is indicated for lesions >25 mm at presentation but <25 mm after chemotherapy. METHOD: Patients who underwent RFA for CRLM after chemotherapy (January 2004-December 2012) were reviewed...
October 10, 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29029497/kras-mutation-is-a-marker-of-worse-oncologic-outcomes-after-percutaneous-radiofrequency-ablation-of-colorectal-liver-metastases
#5
Waleed Shady, Elena N Petre, Efsevia Vakiani, Etay Ziv, Mithat Gonen, Karen T Brown, Nancy E Kemeny, Stephen B Solomon, David B Solit, Constantinos T Sofocleous
BACKGROUND: Kras mutation has been associated with shorter overall survival and time to disease recurrence after resection of colorectal liver metastases (CLM). This study evaluated the prognostic value of Kras mutation in patients with CLM treated by percutaneous radiofrequency ablation (RFA). METHODS: This is an IRB waived retrospective analysis of the impact of KRAS mutation status on oncologic outcomes after CLM RFA. The endpoints were overall survival (OS), local tumor progression (LTP) rates, and incidence of new liver, lung, and peritoneal metastases...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28856283/surgical-treatment-of-liver-tumors-own-experience-and-literature-review
#6
REVIEW
Aliaksandr Tarasik, Jerzy Jaroszewicz, Marcin Januszkiewicz
Despite advances, the treatment of focal liver lesions is still challenging. It requires the experience of a surgeon, improvement of existing and the development of new techniques. The aim of this article is to present a literature review and summarize our experience in liver surgery. Twenty-one patients with various liver tumors were treated in 2015 at the Department of Surgical Oncology of Bialystok Center for Oncology. Mostly patients were diagnosed with colorectal cancer liver metastases or hepatocellular carcinoma...
March 2017: Clin Exp Hepatol
https://www.readbyqxmd.com/read/28777429/changes-of-reduced-glutathione-and-glutathione-s-transferase-levels-in-colorectal-cancer-patients-undergoing-treatment
#7
Edita Baltruskeviciene, Birutė Kazbariene, Eduardas Aleknavicius, Aurelija Krikstaponiene, Lina Venceviciene, Kestutis Suziedelis, Eugenijus Stratilatovas, Janina Didziapetriene
PURPOSE: The available data concerning reduced glutathione (GSH) and glutathione S-transferase (GST) levels in colorectal cancer patients during the treatment process are contradictory and insufficient. METHODS: Forty patients with metastatic colorectal cancer receiving FOLFOX4 chemotherapy with or without bevacizumab and 40 healthy volunteers were included in the study. Blood samples were taken before treatment, after 2 months and at the end of treatment in the patient group and once in the healthy volunteer group...
July 25, 2017: Tumori
https://www.readbyqxmd.com/read/28744081/early-outcomes-of-radiofrequency-ablation-in-unresectable-metastatic-colorectal-cancer-from-a-tertiary-cancer-hospital-in-india
#8
Suyash Kulkarni, Nitin S Shetty, Ashwin M Polnaya, Sushil Patil, Kunal Gala, Rahul Chivate, Vikas Ostwal, Anant Ramaswamy, Shailesh V Shrikhande, Mahesh Goel, Shraddha Patkar, Manish Bhandare, Venkatesh Rangarajan, Purandare Nilendu
AIMS: The study was carried out to evaluate the early outcomes using Radiofrequency Ablation (RFA) for unresectable liver metastases in the management of metastatic colorectal cancer (mCRC) from an area of low endemicity. MATERIAL AND METHODS: 60 Patients with unresectable colorectal liver metastases had undergone 88 sessions of RFA from January 2007 till December 2013. The results were retrospectively analysed to evaluate the outcomes in terms of efficacy and survival rates...
April 2017: Indian Journal of Radiology & Imaging
https://www.readbyqxmd.com/read/28730773/thermal-ablation-may-improve-outcomes-in-patients-with-colorectal-liver-metastasis-a-case-control-study
#9
Loukia S Poulou, Loukas Thanos, Panayiotis D Ziakas, Emmanouel Merikas, Apostolos Achimastos, Constantine Gennatas, Konstantinos N Syrigos
PURPOSE: Local thermal ablation may extend the scope of palliative therapy in patients with colorectal liver metastasis. We performed a retrospective, case-controlled study to compare patients with colorectal liver metastases that were treated with percutaneous radiofrequency (RF) or microwave (MW) thermal ablation, against the control group of chemotherapy alone. METHODS: We described baseline demographics, ablation sessions, procedure duration and related complications...
May 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28730772/a-comparative-study-of-laparoscopic-microwave-ablation-with-laparoscopic-radiofrequency-ablation-for-colorectal-liver-metastasis
#10
Bo Yang, Yuwei Li
PURPOSE: Laparoscopic thermal ablation is a common alternative to surgical resection for treating colorectal liver metastasis, particularly for metastases located in difficult-to-reach regions. This study aimed to compare the short- and longterm outcomes of laparoscopic radiofrequency ablation (LRFA) and laparoscopic microwave ablation (LMWA) used for treating colorectal liver metastasis. METHODS: Data from patients with colorectal liver metastasis who had undergone LRFA or LMWA from January 2010 to January 2016 were examined...
May 2017: Journal of B.U.ON.: Official Journal of the Balkan Union of Oncology
https://www.readbyqxmd.com/read/28728304/-percutaneous-microwave-radiofrequency-ablation-liver-partition-and-portal-vein-embolization-for-planned-hepatectomy-for-colorectal-liver-metastases-with-insufficient-future-liver-remnant
#11
Y B Zhang, D F Hong, X M Fan, Z Y Luo, G L Shen
No abstract text is available yet for this article.
July 23, 2017: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/28722702/radiofrequency-ablation-of-hepatic-tumor-subjective-assessment-of-the-perilesional-vascular-network-on-contrast-enhanced-computed-tomography-before-and-after-ablation-can-reliably-predict-the-risk-of-local-recurrence
#12
Sireesha Yedururi, Silanath Terpenning, Sanjay Gupta, Patricia Fox, Sooyoung Shin Martin, Claudius Conrad, Evelyne M Loyer
OBJECTIVE: To determine whether simple, subjective analysis of the perilesional vascular network can predict the risk of local recurrence after radiofrequency ablation (RFA) of liver malignancies on contrast-enhanced computed tomography (CECT). METHODS: Contrast-enhanced computed tomography's 103 patients (59 men and 44 women; mean age, 63 years (range, 31-84 years) with 134 lesions who underwent RFA between 2000 and 2010 were retrospectively analyzed. The primary tumors include colorectal carcinoma (58 patients), hepatocellular carcinoma (n = 13), breast carcinoma (n = 8), neuroendocrine tumor (n = 5), and others (n = 19)...
July 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28687147/radiofrequency-ablation-compared-to-surgical-resection-for-curative-treatment-of-patients-with-colorectal-liver-metastases-a-meta-analysis
#13
REVIEW
Martinus J van Amerongen, Sjoerd F M Jenniskens, Peter B van den Boezem, Jurgen J Fütterer, Johannes H W de Wilt
BACKGROUND: Hepatic resection and ablative treatments, such as RFA are available treatment options for liver tumors. Advantages and disadvantages of these treatment options in patients with colorectal liver metastases need further evaluation. The purpose of this study was to systematically evaluate the role of radiofrequency ablation (RFA) compared to surgery in the curative treatment of patients with colorectal liver metastases (CRLM). METHODS: A systematic search was performed from MEDLINE, EMBASE and the Cochrane Library for studies directly comparing RFA with resection for CRLM, after which variables were evaluated...
September 2017: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/28681367/expandable-metallic-stent-for-endobronchial-metastasis-from-colorectal-cancer-reports-of-2-cases
#14
Tomoki Nakamura, Takayuki Tajima, Takashi Ogimi, Hiroshi Miyakita, Miho Nitta, Kazunori Myojin, Sakurako Tajiri, Ichiro Kobayashi, Takayuki Nishi, Sotaro Sadahiro, Hideo Shimada
In recent years, there have been many reports about the efficacy of stenting for central bronchial stenosis. When central bronchial stenosis is due to metastasis of a malignant tumor to the trachea and/or bronchi (endobronchial metastasis: EM), it is classified as "narrow EM" and "broad EM." [1] We managed two patients in whom bilateral stent placement was required for narrow and broad EM arising from colorectal cancer. Case 1: In September 2011, a 66-year-old man underwent low anterior resection for advanced colorectal cancer associated with unresectable liver metastasis...
July 20, 2017: Tokai Journal of Experimental and Clinical Medicine
https://www.readbyqxmd.com/read/28655081/-prognostic-analysis-of-colorectal-liver-metastases-treated-by-surgery-combined-with-intraoperative-radiofrequency-ablation
#15
R Mao, J J Zhao, X Y Bi, H Zhao, Z Y Li, Z Huang, Y F Zhang, X Chen, H J Hu, X L Wu, X H Hu, J Q Cai
Objective: To investigate the clinical value of intraoperative radiofrequency ablation (RFA) in the treatment of colorectal liver metastasis (CLM). Methods: A retrospectively analysis of 187 patients with CLM who underwent liver resection with or without RFA from January 2009 to August 2016 in Department of Hepatobiliary Surgery, Cancer Hospital, Chinese Academy of Medical Sciences was performed. According to whether RFA was used intraoperatively, patients were divided into resection only group and combined treatment group...
July 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/28651746/the-management-of-colorectal-liver-metastases
#16
B Maher, E Ryan, M Little, P Boardman, B Stedman
Colorectal cancer remains a leading cause of cancer-related death in Europe. Approximately one-quarter of patients have synchronous hepatic metastases and metachronous liver metastases occur in a further 30%. The scope of surgery in management of colorectal metastases has evolved to include selected patients with extra-hepatic disease for whom R0 resection is considered feasible; however, locoregional treatments are increasingly recognised as viable management options in those patients deemed unsuitable for surgery and there is an expanding body of evidence regarding their ability to achieve local control and increase progression-free survival in the liver...
August 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28643305/-interventional-therapy-of-colorectal-liver-metastasis
#17
Qi Zhang, Gaojun Teng
Colorectal liver metastasis (CRLM) is one of the most difficult and key points in the treatment of colorectal cancer. Approximately 50% to 60% of patients diagnosed as colorectal cancer develops metastasis, and 80% to 90% of CRLM is unresectable. Surgical resection is the first-line treatment for CRLM, while it is only suitable for about 15% patients. Systemic chemotherapy can prolong the survival of CRLM patients, however, a part of CRLM patients are resistant to chemotherapy. With the development of technology and the update of clinical evidence, individual therapy with target drugs and multidisciplinary treatment (MDT) have became a tendency, and minimally invasive interventional therapy has gained more acceptance in the MDT mode of the treatment for CRLM...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28636427/liver-directed-therapy-in-metastatic-colorectal-cancer
#18
REVIEW
Ciara M Kelly, Nancy E Kemeny
Colorectal cancer is a significant global health issue with over 1 million cases diagnosed annually throughout the world. 15% of patients diagnosed with colorectal cancer will have liver metastases and 60% will develop liver metastases if they have metastatic disease. Oligometastatic colorectal cancer confined to the liver represents an intermediate state in the evolution of metastatic capacity that opens the opportunity for local interventions. Areas covered: The literature supports long-term survival if patients undergo liver resection of colorectal metastases...
August 2017: Expert Review of Anticancer Therapy
https://www.readbyqxmd.com/read/28628012/curative-treatment-of-colorectal-cancer-solitary-metastasis-to-liver-subcapsule-by-percutaneous-us-guided-radiofrequency-ablation-using-hydrodissection-case-report
#19
N Paksashvili, T Ninikashvili, T Azrumelashvili, M Mizandari
Case report presents the successful treatment of solitary liver metastasis in a patient with resected colon cancer. A 39-year-old male underwent left hemicolectomy with colostomy formation followed by chemotherapy for a moderately differentiated adenocarcinoma of the colon. Two years later, a liver metastatic lesion was detected. Patient received chemotherapy; the mass remained stable in size, measuring up to 3 cm in diameter. Low-invasive percutaneous curative treatment by Radiofrequency ablation was conducted using hydrodissection by dielectric fluid intraperitoneal introduction for hydrodissection...
May 2017: Georgian Medical News
https://www.readbyqxmd.com/read/28612019/thermal-ablation-in-the-management-of-colorectal-cancer-patients-with-oligometastatic-liver-disease
#20
REVIEW
Elena Nadia Petre, Constantinos Sofocleous
BACKGROUND: Surgical resection of limited colorectal liver disease improves long-term survival and can be curative in a subset of selected cases. Image-guided percutaneous ablation therapies have emerged as safe and effective alternative options for selected patients with unresectable colorectal liver metastases (CLM) that can be ablated with margins. Ablation causes focal destruction of tissue and has increasingly been shown to provide durable eradication of tumors. METHODS: A selective review of literature was conducted in PubMed, focusing on recent studies reporting on the safety, efficacy, and long-term outcomes of percutaneous ablation modalities in the treatment of CLM...
March 2017: Visceral Medicine
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