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radiofrequency ablation colorectal liver

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https://www.readbyqxmd.com/read/29666906/radiofrequency-and-microwave-ablation-compared-to-systemic-chemotherapy-and-to-partial-hepatectomy-in-the-treatment-of-colorectal-liver-metastases-a-systematic-review-and-meta-analysis
#1
Martijn R Meijerink, Robbert S Puijk, Aukje A J M van Tilborg, Kirsten Holdt Henningsen, Llenalia Garcia Fernandez, Mattias Neyt, Juanita Heymans, Jacqueline S Frankema, Koert P de Jong, Dick J Richel, Warner Prevoo, Joan Vlayen
PURPOSE: To assess safety and outcome of radiofrequency ablation (RFA) and microwave ablation (MWA) as compared to systemic chemotherapy and partial hepatectomy (PH) in the treatment of colorectal liver metastases (CRLM). METHODS: MEDLINE, Embase and the Cochrane Library were searched. Randomized trials and comparative observational studies with multivariate analysis and/or matching were included. Guidelines from National Guideline Clearinghouse and Guidelines International Network were assessed using the AGREE II instrument...
April 17, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29651715/can-tumor-coverage-evaluated-24-h-post-radiofrequency-ablation-predict-local-tumor-progression-of-liver-metastases
#2
Frederik Vandenbroucke, Jef Vandemeulebroucke, Nico Buls, Ruedi F Thoeni, Johan de Mey
PURPOSE: To assess the predictive value for local tumor progression (LTP) of geometrical tumor coverage using the contrast-enhanced (ce-)CT images acquired before and within 24 h after radiofrequency (RF) ablation. METHODS: Twenty patients (6 male and 14 female, median age 62 years) with 45 focal hypovascular liver metastases (16 colorectal carcinoma, 3 melanoma and 1 breast carcinoma) underwent RF ablation under CT-guidance and received a ce-PET/CT scan within 24 h post-procedure...
April 12, 2018: International Journal of Computer Assisted Radiology and Surgery
https://www.readbyqxmd.com/read/29619592/the-predictors-and-oncological-outcomes-of-repeat-surgery-for-recurrence-after-hepatectomy-for-colorectal-liver-metastases
#3
Katsunori Imai, Yo-Ichi Yamashita, Yuji Miyamoto, Shigeki Nakagawa, Hirohisa Okabe, Daisuke Hashimoto, Akira Chikamoto, Hideo Baba
PURPOSE: Although recurrence after hepatectomy for colorectal liver metastases (CRLM) is common, the optimal treatment strategy remains unclear. The aims of this study were to clarify the impact of repeat surgery and identify the predictive factors for repeat surgery. METHODS: Among the 170 patients who underwent potentially curative surgery for CRLM, 113 developed recurrence. The predictive factors for the performance of repeat surgery were identified and a predictive model was constructed...
April 4, 2018: International Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29582125/does-the-site-of-the-primary-affect-outcomes-when-ablating-colorectal-liver-metastases-with-radiofrequency-ablation
#4
Yangkui Gu, Zhimei Huang, Haifeng Gu, Fei Gao, Tianqi Zhang, Senmiao Huang, Jinhua Huang
PURPOSE: To determine whether primary tumor side was a predictor of radiofrequency ablation (RFA) outcome in colorectal liver metastases (CRLM). MATERIALS AND METHODS: The institutional review board approved this retrospective study. Written informed consent was obtained from all patients. From January 2007 to December 2013, 102 patients underwent RFA of metachronous CRLM were enrolled in this study with propensity score matching method. Recurrence rate (RR) and overall survival (OS) were analyzed between two patients cohorts with primary left-side colorectal cancer (LSCRC) or primary right-side colon cancer (RSCC)...
March 26, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29543821/radiofrequency-ablation-is-beneficial-in-simultaneous-treatment-of-synchronous-liver-metastases-and-primary-colorectal-cancer
#5
Joost Hof, Hanneke J Joosten, Klaas Havenga, Koert P de Jong
BACKGROUND: In patients with resectable synchronous colorectal liver metastases (CRLM), either two-staged or simultaneous resections of the primary tumor and liver metastases are performed. Data on radiofrequency ablation (RFA) for the treatment of CRLM during a simultaneous procedure is lacking. The primary aim was to analyze short-term and long-term outcome of RFA in simultaneous treatment. A secondary aim was to compare simultaneous resection with the colorectal-first approach. METHODS: Retrospective analysis of 241 patients with colorectal cancer and synchronous CRLM between 2000-2016...
2018: PloS One
https://www.readbyqxmd.com/read/29536242/the-relationship-between-applied-energy-and-ablation-zone-volume-in-patients-with-hepatocellular-carcinoma-and-colorectal-liver-metastasis
#6
Wouter J Heerink, A Millad Solouki, Rozemarijn Vliegenthart, Simeon J S Ruiter, Egbert Sieders, Matthijs Oudkerk, Koert P de Jong
OBJECTIVES: To study the ratio of ablation zone volume to applied energy in computed tomography (CT)-guided radiofrequency ablation (RFA) and microwave ablation (MWA) in patients with hepatocellular carcinoma (HCC) in a cirrhotic liver and in patients with colorectal liver metastasis (CRLM). METHODS: In total, 90 liver tumors, 45 HCCs in a cirrhotic liver and 45 CRLMs were treated with RFA or with one of two MWA devices (MWA_A and MWA_B), resulting in 15 procedures for each tumor type, per device...
March 13, 2018: European Radiology
https://www.readbyqxmd.com/read/29506424/local-recurrence-rate-in-patients-with-colorectal-cancer-liver-metastasis-after-wedge-resection-or-percutaneous-radiofrequency-ablation
#7
Naïk Vietti Violi, Rafael Duran, Nicolas Demartines, Christine Sempoux, Boris Guiu, Pierre E Bize, Nathalie Sala, Nermin Halkic, Jean-Francois Knebel, Alban Denys
PURPOSE: To compare local recurrence (LR) rate in patients with colorectal cancer liver metastasis (CRCLM) after surgical wedge resection (WR) or radiofrequency ablation (RFA) and to investigate predictive factors of LR. MATERIALS AND METHODS: This single-centre, retrospective, institutional review board-approved study including 43 consecutive patients with 121 metastases treated by WR and 60 patients with 110 metastases treated by RFA between 2007 and 2014 with 23 and 18...
March 5, 2018: International Journal of Hyperthermia
https://www.readbyqxmd.com/read/29454099/two-stage-hepatectomy-vs-one-stage-major-hepatectomy-with-contralateral-resection-or-ablation-for-advanced-bilobar-colorectal-liver-metastases
#8
Takashi Mizuno, Jordan M Cloyd, Kiyohiko Omichi, Yun Shin Chun, Claudius Conrad, Ching-Wei D Tzeng, Steven H Wei, Thomas A Aloia, Jean-Nicolas Vauthey
BACKGROUND: Both 2-stage hepatectomy (TSH) and 1-stage hepatectomy (OSH) represent feasible strategies for resection of advanced bilobar colorectal liver metastases (CLM). However, the influence of the surgical approach on postoperative outcomes and overall survival (OS) is unknown. To define the optimal surgical approach for advanced bilobar CLM requiring right hemihepatectomy, we compared short-term and long-term outcomes after TSH and OSH with contralateral resection or radiofrequency ablation (RFA)...
May 2018: Journal of the American College of Surgeons
https://www.readbyqxmd.com/read/29423737/aggressive-and-multidisciplinary-local-approach-to-iterative-recurrences-of-colorectal-liver-metastases
#9
Luca Viganò, Vittorio Pedicini, Tiziana Comito, Carlo Carnaghi, Guido Costa, Dario Poretti, Ciro Franzese, Nicola Personeni, Daniele Del Fabbro, Lorenza Rimassa, Marta Scorsetti, Armando Santoro, Luigi Solbiati, Guido Torzilli
BACKGROUND: Liver resection (LR) of colorectal metastases is associated with high recurrence risk. Aggressive local retreatment is advocated, but further recurrences may occur. Poor is known about presentation, treatment, and outcome of iterative recurrences. METHODS: A series of 323 consecutive patients undergoing first LR in the period 2004-2013 was reviewed. Patients with recurrence were included. Any local treatment (surgery, radiofrequency ablation (RFA) and stereotactic body radiation therapy (SBRT)) was analyzed...
February 8, 2018: World Journal of Surgery
https://www.readbyqxmd.com/read/29395898/impact-of-prior-hepatectomy-history-on-local-tumor-progression-after-percutaneous-ablation-of-colorectal-liver-metastases
#10
Bruno C Odisio, Suguru Yamashita, Steven Y Huang, Scott E Kopetz, Kamran Ahrar, Takashi Mizuno, Claudius Conrad, Thomas A Aloia, Yun Shin Chun, Sanjay Gupta, Jean-Nicolas Vauthey
PURPOSE: To test the hypothesis that, given the current resection eligibility criteria for colorectal liver metastasis (CLM), prior hepatectomy would be associated with improved local tumor control and survival after percutaneous ablation of CLMs. MATERIALS AND METHODS: This single-institution retrospective study included 82 consecutive patients with 97 CLMs treated with ablation (radiofrequency ablation, microwave ablation, or cryoablation) from January 2005 to December 2014...
March 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29394799/-radiofrequency-ablation-pulmonary-metastasis-of-colorectal-cancer-two-cases-of-report
#11
Akihito Babaya, Masafumi Noda, Ayako Imada, Jihyung Song, Kei Kimura, Michiko Hamanaka, Masayoshi Kobayashi, Kiyoshi Tsukamoto, Tomoki Yamano, Masataka Ikeda, Naohiro Tomita
Case 1: 63-year-old woman received abdominoperineal resection with lateral lymph node dissection for rectal cancer in 2008. After adjuvant chemotherapy, she suffered from lung metastasis and received partial pneumonectomy in 2012. However, chemotherapy was performed again for lung metastasis and mediastinal lymph nodes in 2013. Radiofrequency ablation (RFA)was performed to lung metastasis in 2016 due to ineffectiveness of chemotherapy. Case 2: 81-year-old man received Hartmann's procedure for rectal cancer with lung and liver metastasis in 2012...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29394766/-two-cases-of-colorectal-cancer-with-src-amplification
#12
Hidehito Oyanagi, Yoshifumi Shimada, Ryoma Yagi, Yosuke Tajima, Hiroshi Ichikawa, Mae Nakano, Masato Nakano, Masayuki Nagahashi, Jun Sakata, Hitoshi Kameyama, Takashi Kobayashi, Hitoshi Nogami, Satoshi Maruyama, Yasumasa Takii, Toshifumi Wakai
Carcinoma with elevated SRC expression is associated with distant metastasis and drug resistance. We report 2 cases of SRC amplification observed after retrospective comprehensive genomic sequencing. Case 1 was a 62-year-old man who had RAS wild-type stage IV carcinoma of the sigmoid colon with multiple liver metastases in both lobes. He underwent low anterior resection and systemic chemotherapy was initiated to treat the unresectable multiple liver metastases. Case 2 was a 73-yearold man who had RAS wild-type stage IV carcinoma of the descending colon with metastasis in the lateral segment of the liver...
November 2017: Gan to Kagaku Ryoho. Cancer & Chemotherapy
https://www.readbyqxmd.com/read/29273176/local-recurrence-after-microwave-thermosphere-ablation-of-malignant-liver-tumors-results-of-a-surgical-series
#13
Hideo Takahashi, Bora Kahramangil, Eren Berber
BACKGROUND: Microwave thermosphere ablation is a new treatment modality that creates spherical ablation zones using a single antenna. This study aims to analyze local recurrence associated with this new treatment modality in patients with malignant liver tumors. METHODS: This is a prospective clinical study of patients who underwent microwave thermosphere ablation of malignant liver tumors between September 2014 and March 2017. Clinical, operative, and oncologic parameters were analyzed using Kaplan-Meier survival and Cox proportional hazards model...
April 2018: Surgery
https://www.readbyqxmd.com/read/29203394/percutaneous-microwave-versus-radiofrequency-ablation-of-colorectal-liver-metastases-ablation-with-clear-margins-a0-provides-the-best-local-tumor-control
#14
Waleed Shady, Elena N Petre, Kinh Gian Do, Mithat Gonen, Hooman Yarmohammadi, Karen T Brown, Nancy E Kemeny, Michael D'Angelica, Peter T Kingham, Stephen B Solomon, Constantinos T Sofocleous
PURPOSE: To identify and compare predictors of local tumor progression (LTP)-free survival (LTPFS) after radiofrequency (RF) ablation and microwave (MW) ablation of colorectal liver metastases (CLMs). MATERIALS AND METHODS: This is a retrospective review of CLMs ablated from November 2009 to April 2015 (110 patients). Margins were measured on contrast-enhanced computed tomography (CT) 6 weeks after ablation. Clinical and technical predictors of LTPFS were assessed using a competing risk model adjusted for clustering...
February 2018: Journal of Vascular and Interventional Radiology: JVIR
https://www.readbyqxmd.com/read/29113650/laparoscopic-parenchymal-preserving-liver-resections-for-colorectal-liver-metastases-in-the-era-of-highly-effective-systemic-therapy-and-selective-internal-radiation-therapy-can-often-prevent-a-hemihepatectomy-with-video
#15
Mathieu D'Hondt, Frédéric Ververken, Frederiek Nuytens
BACKGROUND: Preservation of hepatic parenchyma is important in liver surgery to prevent postoperative liver failure and according to some reports it could offer a prolonged survival and lower recurrence rates compared to major hepatectomies in patients with colorectal liver metastases. However, laparoscopic parenchyma-preserving liver resections can be technically challenging. The aim of this video is to illustrate the concept of laparoscopic parenchymal-preserving liver resections after conversion chemotherapy with targeted therapy...
December 2017: Surgical Oncology
https://www.readbyqxmd.com/read/29063852/local-control-outcomes-using-stereotactic-body-radiation-therapy-for-liver-metastases-from-colorectal-cancer
#16
Ji Hyeon Joo, Jin-Hong Park, Jin Cheon Kim, Chang Sik Yu, Seok-Byung Lim, In Ja Park, Tae Won Kim, Yong Sang Hong, Kyu-Pyo Kim, Sang Min Yoon, Jongmoo Park, Jong Hoon Kim
PURPOSE: To evaluate the effective dose and patterns of recurrence after stereotactic body radiation therapy (SBRT) for hepatic metastases that arise from colorectal cancer. METHODS AND MATERIALS: A cohort of 70 patients with 103 colorectal liver metastases were treated with SBRT at a single institution. The prescribed doses were 45 to 60 Gy in 3 to 4 fractions, but these were modified according to the tolerance of the adjacent normal tissue. To allow for dose comparisons, a biological equivalent dose was calculated...
November 15, 2017: International Journal of Radiation Oncology, Biology, Physics
https://www.readbyqxmd.com/read/29061837/immediate-and-long-term-results-of-radiofrequency-ablation-for-colorectal-liver-metastases
#17
Ciprian Cirimbei, Vlad Rotaru, Elena Chitoran, Oana Pavaleanu, Simona Elena Cirimbei
BACKGROUND/AIM: Radiofrequency ablation (RFA) of colorectal liver metastases (CRLMs) is a method developed in the last 15 years. It provides an acceptable control of the malignant process with lower risks compared to surgical resection. The aim of the study was to assess immediate and long-term results, including recurrence, survival, morbidity/mortality rates after RFA. PATIENTS AND METHODS: Sixty-two cases with CRLMs were treated by RFA during open surgery (89 lesions)...
November 2017: Anticancer Research
https://www.readbyqxmd.com/read/29029986/radiofrequency-ablation-for-colorectal-cancer-liver-metastases-initially-greater-than-25-mm-but-downsized-by-neo-adjuvant-chemotherapy-is-associated-with-increased-rate-of-local-tumor-progression
#18
Léonor Benhaim, Mostafa El Hajjam, Robert Malafosse, Jacques Sellier, Catherine Julie, Alain Beauchet, Bernard Nordlinger, Frédérique Peschaud
BACKGROUND: Radiofrequency ablation (RFA) is a valid treatment for liver metastases from colorectal cancer (CRLM) smaller than 25 mm and unsuitable for surgical resection. Tumor size is predictive for local tumor progression (LTP). The aim of this study was to evaluate whether RFA is indicated for lesions >25 mm at presentation but <25 mm after chemotherapy. METHOD: Patients who underwent RFA for CRLM after chemotherapy (January 2004-December 2012) were reviewed...
January 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29029497/kras-mutation-is-a-marker-of-worse-oncologic-outcomes-after-percutaneous-radiofrequency-ablation-of-colorectal-liver-metastases
#19
Waleed Shady, Elena N Petre, Efsevia Vakiani, Etay Ziv, Mithat Gonen, Karen T Brown, Nancy E Kemeny, Stephen B Solomon, David B Solit, Constantinos T Sofocleous
BACKGROUND: Kras mutation has been associated with shorter overall survival and time to disease recurrence after resection of colorectal liver metastases (CLM). This study evaluated the prognostic value of Kras mutation in patients with CLM treated by percutaneous radiofrequency ablation (RFA). METHODS: This is an IRB waived retrospective analysis of the impact of KRAS mutation status on oncologic outcomes after CLM RFA. The endpoints were overall survival (OS), local tumor progression (LTP) rates, and incidence of new liver, lung, and peritoneal metastases...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28856283/surgical-treatment-of-liver-tumors-own-experience-and-literature-review
#20
REVIEW
Aliaksandr Tarasik, Jerzy Jaroszewicz, Marcin Januszkiewicz
Despite advances, the treatment of focal liver lesions is still challenging. It requires the experience of a surgeon, improvement of existing and the development of new techniques. The aim of this article is to present a literature review and summarize our experience in liver surgery. Twenty-one patients with various liver tumors were treated in 2015 at the Department of Surgical Oncology of Bialystok Center for Oncology. Mostly patients were diagnosed with colorectal cancer liver metastases or hepatocellular carcinoma...
March 2017: Clinical and Experimental Hepatology
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