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https://www.readbyqxmd.com/read/28335517/state-of-the-art-on-functional-virgin-olive-oils-enriched-with-bioactive-compounds-and-their-properties
#1
REVIEW
Patricia Reboredo-Rodríguez, María Figueiredo-González, Carmen González-Barreiro, Jesús Simal-Gándara, María Desamparados Salvador, Beatriz Cancho-Grande, Giuseppe Fregapane
Virgin olive oil, the main fat of the Mediterranean diet, is per se considered as a functional food-as stated by the European Food Safety Authority (EFSA)-due to its content in healthy compounds. The daily intake of endogenous bioactive phenolics from virgin olive oil is variable due to the influence of multiple agronomic and technological factors. Thus, a good strategy to ensure an optimal intake of polyphenols through habitual diet would be to produce enriched virgin olive oil with well-known bioactive polyphenols...
March 20, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28330458/the-effects-of-an-extensive-exercise-programme-on-the-progression-of-mild-cognitive-impairment-mci-study-protocol-for-a-randomised-controlled-trial
#2
Kate E Devenney, Brian Lawlor, Marcel G M Olde Rikkert, Stefan Schneider
BACKGROUND: Exercise interventions to prevent dementia and delay cognitive decline have gained considerable attention in recent years. Human and animal studies have demonstrated that regular physical activity targets brain function by increasing cognitive reserve. There is also evidence of structural changes caused by exercise in preventing or delaying the genesis of neurodegeneration. Although initial studies indicate enhanced cognitive performance in patients with mild cognitive impairment (MCI) following an exercise intervention, little is known about the effect of an extensive, controlled and regular exercise regimen on the neuropathology of patients with MCI...
March 22, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28301496/equity-in-healthcare-for-coronary-heart-disease-wales-uk-2004-2010-a-population-based-electronic-cohort-study
#3
William King, Arron Lacey, James White, Daniel Farewell, Frank Dunstan, David Fone
BACKGROUND: Despite substantial falls in coronary heart disease (CHD) mortality in the United Kingdom (UK), marked socioeconomic inequalities in CHD risk factors and CHD mortality persist. We investigated whether inequity in CHD healthcare in Wales (UK) could contribute to the observed social gradient in CHD mortality. METHODS AND FINDINGS: Linking data from primary and secondary care we constructed an electronic cohort of individuals (n = 1199342) with six year follow-up, 2004-2010...
2017: PloS One
https://www.readbyqxmd.com/read/28297132/vitamin-d-bones-and-muscle-myth-versus-reality
#4
REVIEW
Gustavo Duque, Robin M Daly, Kerrie Sanders, Douglas P Kiel
OBJECTIVES: Evidence regarding the efficacy and dosing of vitamin D on fall and fracture prevention, with or without calcium, is characterised by uncertainty. METHODS: A panel of experts was organised at the First Australasian Conference on Sarcopenia and Frailty in Melbourne, Australia, in November 2016 to provide an interpretation of the current evidence and to give their opinions regarding the supplementation of vitamin D in three hypothetical cases. RESULTS AND CONCLUSION: The authors conclude that (i) target serum 25(OH)D concentration should be 50 to 60 nmol/L year round, with a conservative upper limit <100 nmol/L; (ii) change in serum concentrations at any given dose is highly variable among individuals; (iii) dosing interval may need to be <2 months to have a continuous benefit; (iv) a loading dose can raise levels to target quickly, but there is no evidence yet that this has any positive effect on falls or fracture outcomes; and (v) a maintenance dose of 1000 IU/day, or given as an equivalent dose weekly or monthly, is sufficient for most individuals...
March 2017: Australasian Journal on Ageing
https://www.readbyqxmd.com/read/28295847/effects-on-leisure-activities-and-social-participation-of-a-case-management-intervention-for-frail-older-people-living-at-home-a-randomised-controlled-trial
#5
Marianne Granbom, Jimmie Kristensson, Magnus Sandberg
Frailty causes disability and restrictions on older people's ability to engage in leisure activities and for social participation. The objective of this study was to evaluate the effects of a 1-year case management intervention for frail older people living at home in Sweden in terms of social participation and leisure activities. The study was a randomised controlled trial with repeated follow-ups. The sample (n = 153) was consecutively and randomly assigned to intervention (n = 80) or control groups (n = 73)...
March 12, 2017: Health & Social Care in the Community
https://www.readbyqxmd.com/read/28286988/exercise-and-nutritional-approaches-to-prevent-frail-bones-falls-and-fractures-an-update
#6
REVIEW
R M Daly
Osteoporosis (low bone strength) and sarcopenia (low muscle mass, strength and/or impaired function) often co-exist (hence the term 'sarco-osteoporosis') and have similar health consequences with regard to disability, falls, frailty and fractures. Exercise and adequate nutrition, particularly with regard to vitamin D, calcium and protein, are key lifestyle approaches that can simultaneously optimize bone, muscle and functional outcomes in older people, if they are individually tailored and appropriately prescribed in terms of the type and dose...
April 2017: Climacteric: the Journal of the International Menopause Society
https://www.readbyqxmd.com/read/28266112/dental-caries-and-periodontal-diseases-in-the-ageing-population-call-to-action-to-protect-and-enhance-oral-health-and-well-being-as-an-essential-component-of-healthy-ageing-consensus-report-of-group-4-of-the-joint-efp-orca-workshop-on-the-boundaries-between
#7
Maurizio S Tonetti, Peter Bottenberg, Georg Conrads, Peter Eickholz, Peter Heasman, Marie-Charlotte Huysmans, Rodrigo López, Phoebus Madianos, Frauke Müller, Ian Needleman, Bente Nyvad, Philip M Preshaw, Iain Pretty, Stefan Renvert, Falk Schwendicke, Leonardo Trombelli, Gert-Jan van der Putten, Jacques Vanobbergen, Nicola West, Alix Young, Sebastian Paris
BACKGROUND: Over the last two decades, progress in prevention and treatment of caries and periodontal diseases has been translated to better oral health and improved tooth retention in the adult population. The ageing population and the increasing expectations of good oral health-related quality of life in older age pose formidable challenges to clinical care and healthcare systems. AIMS: The objective of this workshop was to critically review scientific evidence and develop specific recommendations to: (i) prevent tooth loss and retain oral function through prevention and treatment of caries and periodontal diseases later in life and (ii) increase awareness of the health benefits of oral health as an essential component of healthy ageing...
March 2017: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/28265682/-influence-of-skeletal-muscles-on-the-risk-of-falling-in-old-age
#8
D Schöne, E Freiberger, C C Sieber
Falls in older adults are a major public health problem, affecting 1 in 3 persons aged 65 and over at least once a year. Consequences of falling include death, injuries, fear of falling, and subsequent loss of independence. The age-related loss of muscle mass and function (sarcopenia) as well as muscle strength are markers of the frailty syndrome. In addition, they are associated with physical function and are a risk factor for falling. Older adults should be screened for falls at least annually. If evaluated as at-risk, a comprehensive falls assessment should be conducted to determine an individual's risk profile...
March 6, 2017: Der Internist
https://www.readbyqxmd.com/read/28263373/falls-and-frailty-in-prostate-cancer-survivors-current-past-and-never-users-of-androgen-deprivation-therapy
#9
Kerri M Winters-Stone, Esther Moe, Julie N Graff, Nathan F Dieckmann, Sydnee Stoyles, Carolyn Borsch, Joshi J Alumkal, Christopher L Amling, Tomasz M Beer
OBJECTIVES: To compare the prevalence of and association between falls and frailty of prostate cancer survivors (PCSs) who were current, past or never users of androgen deprivation therapy (ADT). DESIGN: Cross-sectional. SETTING: Mail and electronic survey. PARTICIPANTS: PCSs (N = 280; mean age 72 ± 8). MEASUREMENTS: Cancer history, falls, and frailty status (robust, prefrail, frail) using traditionally defined and obese phenotypes...
March 6, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28244550/public-health-impact-of-frailty-role-of-physical-therapists
#10
A M Gustavson, J R Falvey, C M Jankowski, J E Stevens-Lapsley
Frailty is an emerging and immediate public health concern given the growing aging population. The condition of frailty is characterized by a reduction in physiologic reserve, which places frail older adults at considerable risk for further functional decline, hospitalization, institutionalization, and death. Recent research suggests that frailty may be reversible, which could result in significant improvement in public health. Thus, a strong impetus exists to develop strategies for frail older adults that achieve the Triple Aim through better promotion of population health, optimization of patient experiences, and delivery of high-quality care at minimal cost...
2017: Journal of Frailty & Aging
https://www.readbyqxmd.com/read/28210943/faces-of-frailty-in-aging-with-hiv-infection
#11
REVIEW
Marion Thurn, Deborah R Gustafson
PURPOSE OF THE REVIEW: The number of adults who are aging successfully and have HIV infection is increasing. More effective antiretroviral therapy (ART) regimens are preventing individuals infected with HIV from reaching end stages of the HIV infection and developing AIDS (acquired immunodeficiency syndrome). However, even at lower viral loads, chronic HIV infection appears to have consequences on aging processes, including the development of frailty. RECENT FINDINGS: Frailty is a term used to describe vulnerability in aging...
February 2017: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/28202426/integrated-platform-for-home-services-using-new-products-and-services-for-senior-citizens-call-cnav-carsat-2015
#12
Michel Noguès, Daniel Laune, Delphine Paccard, Anne-Laure Coupet, Justine Millot-Keurinck, Narjis Bototo, Marine Bertrand, Jean Bousquet
This project is part of: i) the risks of ageing prevention policy of the French retirement and occupational health insurance agency of Languedoc Roussillon (Carsat-LR) and ii) the European innovation partnership on active and healthy ageing (EIP on AHA). It aims to support senior citizens who live independently and have been identified at risk of frailty on a social or health level. The purpose is to increase legibility as well as technical and financial access to innovations for vulnerable seniors who are remote from the digital era, through a multiservice user-friendly platform...
February 15, 2017: Gériatrie et Psychologie Neuropsychiatrie du Vieillissement
https://www.readbyqxmd.com/read/28196791/use-of-information-and-communication-technologies-among-older-people-with-and-without-frailty-a-population-based-survey
#13
Niina Susanna Keränen, Maarit Kangas, Milla Immonen, Heidi Similä, Heidi Enwald, Raija Korpelainen, Timo Jämsä
BACKGROUND: Use of information and communication technologies (ICT) among seniors is increasing; however, studies on the use of ICT by seniors at the highest risk of health impairment are lacking. Frail and prefrail seniors are a group that would likely benefit from preventive nutrition and exercise interventions, both of which can take advantage of ICT. OBJECTIVE: The objective of the study was to quantify the differences in ICT use, attitudes, and reasons for nonuse among physically frail, prefrail, and nonfrail home-dwelling seniors...
February 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28188558/rationale-for-a-preliminary-operational-definition-of-physical-frailty-and-sarcopenia-in-the-sprintt-trial
#14
Matteo Cesari, Francesco Landi, Riccardo Calvani, Antonio Cherubini, Mauro Di Bari, Patrick Kortebein, Susanna Del Signore, Regis Le Lain, Bruno Vellas, Marco Pahor, Ronenn Roubenoff, Roberto Bernabei, Emanuele Marzetti
In the present article, the rationale that guided the operationalization of the theoretical concept of physical frailty and sarcopenia (PF&S), the condition of interest for the "Sarcopenia and Physical Frailty in Older People: Multicomponent Treatment Strategies" (SPRINTT) trial, is presented. In particular, the decisions lead to the choice of the adopted instruments, and the reasons for setting the relevant thresholds are explained. In SPRINTT, the concept of physical frailty is translated with a Short Physical Performance Battery score of ≥3 and ≤9...
February 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28183454/frailty-and-nutrition-from-epidemiological-and-clinical-evidence-to-potential-mechanisms
#15
REVIEW
Mary Yannakoulia, Eva Ntanasi, Costas A Anastasiou, Nikolaos Scarmeas
Frailty is a geriatric condition characterized by unintentional weight loss, low muscle strength, feeling of exhaustion, reduced physical activity capacity and slow walking speed. Theoretically, nutrition is a factor closely related to the frailty syndrome: all frailty criteria are more or less affected by poor eating habits, whereas frailty itself may have a negative effect on eating and, thus, on the nutritional status. Indeed, research data suggest an association between frailty and specific constituents of diet, namely protein and energy intake, as well as intakes of specific micronutrients...
March 2017: Metabolism: Clinical and Experimental
https://www.readbyqxmd.com/read/28181204/physical-activity-and-exercise-as-countermeasures-to-physical-frailty-and-sarcopenia
#16
Emanuele Marzetti, Riccardo Calvani, Matteo Tosato, Matteo Cesari, Mauro Di Bari, Antonio Cherubini, Marianna Broccatelli, Giulia Savera, Mariaelena D'Elia, Marco Pahor, Roberto Bernabei, Francesco Landi
The identification of cost-effective interventions that improve the health status and prevent disability in old age is one of the most important public health challenges. Regular physical activity is the only intervention that has consistently been shown to improve functional health and energy balance and to reduce the risk of cardiovascular disease, stroke, diabetes, several cancers, depression and falls. In advanced age, physical activity is also effective at mitigating sarcopenia, restoring robustness, and preventing/delaying the development of disability...
February 8, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28178370/barriers-and-enablers-to-adherence-to-anticoagulation-in-heart-failure-with-atrial-fibrillation-patient-and-provider-perspectives
#17
Caleb Ferguson, Sally C Inglis, Phillip J Newton, Sandy Middleton, Peter S Macdonald, Patricia M Davidson
AIMS & OBJECTIVES: The purpose of this study was to elucidate the barriers and enablers to adherence to anticoagulation in individuals with chronic heart failure (CHF) with concomitant atrial fibrillation (AF) from the perspective of patients and providers. BACKGROUND: CHF and AF commonly coexist and are associated with increased stroke risk and mortality. Oral anticoagulation significantly reduces stroke risk and improves outcomes. Yet, in approximately 30% of cases anticoagulation is not commenced for a variety of reasons...
February 8, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28160252/preventing-mobility-disability-in-europe-a-health-economics-perspective-from-the-sprintt-study
#18
Nicolas Sirven, Thomas Rapp, Silvia Coretti, Matteo Ruggeri, Americo Cicchetti
In a global context of population aging, gaining better knowledge of the mechanisms leading to loss of autonomy has become a major objective, notably with the aim of implementing effective preventive health policies. The concept of frailty, originally introduced in gerontology and geriatrics as a precursor state to functional dependency, appears as a useful tool in this specific context. The "Sarcopenia and Physical fRailty IN older people: multi-componenT Treatment strategies" (SPRINTT) project will provide a unique opportunity to explore health economics issues associated with frailty...
February 3, 2017: Aging Clinical and Experimental Research
https://www.readbyqxmd.com/read/28159055/design-of-a-frailty-index-among-community-living-middle-aged-and-older-people-the-rotterdam-study
#19
Josje D Schoufour, Nicole S Erler, Loes Jaspers, Jessica C Kiefte-de Jong, Trudy Voortman, Gijsbertus Ziere, Jan Lindemans, Caroline C Klaver, Henning Tiemeier, Bruno Stricker, Arfan M Ikram, Joop S E Laven, Guy G O Brusselle, Fernando Rivadeneira, Oscar H Franco
OBJECTIVES: To design a frailty index (FI) and evaluate three methods to handle missing data. Furthermore, we evaluated its construct (i.e., skewed distribution, correlation with age and sub-maximum score) and criterion validity (based on mortality risk). STUDY DESIGN: We included 11,539 participants (45± years) from a population-based cohort in the Netherlands. Frailty was measured with a FI, which we constructed based on the accumulation of 45 health-related variables, related to mood, cognition, functional status, diseases and conditions, biomarkers, and nutritional status...
March 2017: Maturitas
https://www.readbyqxmd.com/read/28155183/sarcopenia-an-overview
#20
Emanuele Marzetti, Riccardo Calvani, Matteo Tosato, Matteo Cesari, Mauro Di Bari, Antonio Cherubini, Agnese Collamati, Emanuela D'Angelo, Marco Pahor, Roberto Bernabei, Francesco Landi
Sarcopenia, the age-dependent loss of muscle mass and function, is a common condition among older adults, and is associated with several adverse health outcomes. Owing to the impact of sarcopenia on quality of life, disability and mortality, a greater awareness is necessary in order to correctly identify the condition both in community and geriatric settings. Research on sarcopenia prevention and treatment is developing quickly, but many questions are still unanswered. The core of the sarcopenia condition involves quantitative and qualitative losses of skeletal muscle...
February 2, 2017: Aging Clinical and Experimental Research
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