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frailty prevention

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https://www.readbyqxmd.com/read/28549703/integrated-care-enhancing-the-role-of-the-primary-health-care-professional-in-preventing-functional-decline-a-systematic-review
#1
REVIEW
John E Morley, Hidenori Arai, Li Cao, Birong Dong, Reshma A Merchant, Bruno Vellas, Renuka Visvanathan, Jean Woo
BACKGROUND: Although the older population is increasing worldwide, there is a marked deficit in the number of persons trained in geriatrics. It is now recognized that early detection and treatment of geriatric syndromes (frailty, sarcopenia, anorexia of aging, and cognitive decline) will delay or avert the development of disability. OBJECTIVES: To identify simple screening programs available for primary health professionals to identify geriatric syndromes. DATA SOURCES: PubMed for the last 5 years and study authors...
June 1, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28538797/-evaluation-of-municipal-administration-of-healthcare-actions-for-the-elderly
#2
Keila Cristina Rausch Pereira, Josimari Telino de Lacerda, Sonia Natal
Aging individuals can experience frailty and loss of independence and autonomy. Healthcare for the elderly should help them recover their health and maintain their autonomy, in keeping with the Brazilian Statute of the Elderly and underlying policies in the Brazilian Unified National Health System. Based on a multiple case study, the objective was to assess the capacity of municipal administration to provide healthcare for the elderly. The assessment was oriented by an evaluative model validated by experts in administration and evaluation, with 16 indicators analyzing political, organizational, technical, and operational factors...
May 18, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28537328/frailty-in-relation-to-the-risk-of-alzheimer-s-disease-dementia-and-death-in-older-chinese-adults-a-seven-year-prospective-study
#3
C Wang, X Ji, X Wu, Z Tang, X Zhang, S Guan, H Liu, X Fang
OBJECTIVES: To explore the relationship of general health decline assessed by frailty and risk of dementia and Alzheimer's disease (AD). DESIGN: A seven-year prospective cohort study. SETTING: Secondary analysis of data from the Beijing Longitudinal Study on Aging. PARTICIPANTS: Urban and rural community-dwelling people aged 60 and older at baseline. MEASUREMENTS: Frailty was quantified using the deficit accumulation-based frailty index (FI), constructed from 40 health deficits at baseline...
2017: Journal of Nutrition, Health & Aging
https://www.readbyqxmd.com/read/28527626/the-impact-of-economic-conditions-on-the-disablement-process-a-markov-transition-approach-using-share-data
#4
Y Arrighi, T Rapp, N Sirven
A growing number of studies underline the relationship between socioeconomic status and health at older ages. Following that literature, we explore the impact of economic conditions on changes in functional health overtime. Frailty, a state of physiological instability, has been identified in the public health literature as a candidate for disability prevention but received little attention from health economists. Using SHARE panel data, respondents aged 50 and over from ten European countries were categorised as robust, frail and dependent...
May 10, 2017: Health Policy
https://www.readbyqxmd.com/read/28525586/prevalence-and-correlates-of-frailty-among-community-dwelling-chinese-older-adults-the-china-health-and-retirement-longitudinal-study
#5
Chenkai Wu, Ellen Smit, Qian-Li Xue, Michelle C Odden
Background.: Frailty is an age-related clinical syndrome of decreased resilience to stressors and is associated with numerous adverse outcomes. Although there is preponderance of literature on frailty in developed countries, limited investigations have been conducted in less developed regions including China-a country that has the world's largest aging population. We examined frailty prevalence in China by socio-demographics and geographic region, and investigated correlates of frailty...
May 19, 2017: Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
https://www.readbyqxmd.com/read/28514618/aerobic-or-resistance-exercise-or-both-in-dieting-obese-older-adults
#6
RANDOMIZED CONTROLLED TRIAL
Dennis T Villareal, Lina Aguirre, A Burke Gurney, Debra L Waters, David R Sinacore, Elizabeth Colombo, Reina Armamento-Villareal, Clifford Qualls
BACKGROUND: Obesity causes frailty in older adults; however, weight loss might accelerate age-related loss of muscle and bone mass and resultant sarcopenia and osteopenia. METHODS: In this clinical trial involving 160 obese older adults, we evaluated the effectiveness of several exercise modes in reversing frailty and preventing reduction in muscle and bone mass induced by weight loss. Participants were randomly assigned to a weight-management program plus one of three exercise programs - aerobic training, resistance training, or combined aerobic and resistance training - or to a control group (no weight-management or exercise program)...
May 18, 2017: New England Journal of Medicine
https://www.readbyqxmd.com/read/28506216/nutritional-determinants-of-frailty-in-older-adults-a-systematic-review
#7
Laura Lorenzo-López, Ana Maseda, Carmen de Labra, Laura Regueiro-Folgueira, José L Rodríguez-Villamil, José C Millán-Calenti
BACKGROUND: Frailty is a geriatric syndrome that affects multiple domains of human functioning. A variety of problems contributes to the development of this syndrome; poor nutritional status is an important determinant of this condition. The purpose of this systematic review was to examine recent evidence regarding the association between nutritional status and frailty syndrome in older adults. METHODS: PubMed, Web of Science, and Scopus electronic databases were searched using specific key words, for observational papers that were published during the period from 2005 to February 2017 and that studied the association or relationship between nutritional status and frailty in older adults...
May 15, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28505140/self-management-group-exercise-extends-healthy-life-expectancy-in-frail-community-dwelling-older-adults
#8
Minoru Yamada, Hidenori Arai
Preventing frailty and its adverse health outcomes is crucial in countries with a large elderly population, such as Japan. Since the long-term care insurance (LTCI) system was launched, the number of certified older adults with LTCI service requirement has continued to increase. This is a serious problem, because the LTCI service requirement certification is equivalent to disability. The aim of this study was to evaluate the effect of a self-management group intervention on new LTCI service requirement certifications in community-dwelling older adults in Japan...
May 15, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28501417/prevalence-of-frailty-assessed-by-fried-and-kihon-checklist-indexes-in-a-prospective-cohort-study-design-and-demographics-of-the-kyoto-kameoka-longitudinal-study
#9
Yosuke Yamada, Hinako Nanri, Yuya Watanabe, Tsukasa Yoshida, Keiichi Yokoyama, Aya Itoi, Heiwa Date, Miwa Yamaguchi, Motoko Miyake, Emi Yamagata, Hajime Tamiya, Miho Nishimura, Mami Fujibayashi, Naoyuki Ebine, Mitsuyoshi Yoshida, Takeshi Kikutani, Eiichi Yoshimura, Kazuko Ishikawa-Takata, Minoru Yamada, Tomoki Nakaya, Yasuko Yoshinaka, Yoshinori Fujiwara, Hidenori Arai, Misaka Kimura
OBJECTIVE: The Kyoto-Kameoka Study was launched in 2011-2012 to identify the associations among food intake, nutritional status, physical activity, oral function, quality of life or social capital, the use of long-term care insurance (LTCI) system, and healthy lifespan in community-dwelling older people as a part of the World Health Organization Safe Community program. DESIGN: A prospective cohort study, reporting baseline demographics (cross-sectional data). SETTING AND PARTICIPANTS: We conducted 2 mailed self-administered questionnaire surveys; one is a complete population survey with a comprehensive survey of needs in the sphere of daily life (NSDL) that included 2 different frailty indexes, the Kihon Checklist (KCL) and the Fried phenotype, socioeconomic status, general and psychological health, and social relationships; followed by the more detailed Health and Nutrition Survey...
May 11, 2017: Journal of the American Medical Directors Association
https://www.readbyqxmd.com/read/28499379/diet-with-a-combination-of-high-protein-and-high-total-antioxidant-capacity-is-strongly-associated-with-low-prevalence-of-frailty-among-old-japanese-women-a-multicenter-cross-sectional-study
#10
Satomi Kobayashi, Hitomi Suga, Satoshi Sasaki
BACKGROUND: The intake of protein and antioxidants has been inversely associated with frailty, individually. However, to our knowledge, no study has evaluated these associations in considering antioxidants or protein intakes as respective confounders. Further, the cooperative effect of dietary protein and antioxidants on frailty has not been investigated. Therefore, we examined the association of high protein and high dietary total antioxidant capacity (TAC) with frailty under the adjustment for dietary TAC or protein intake, respectively...
May 12, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28498183/impact-of-facility-and-community-based-peer-support-models-on-maternal-uptake-and-retention-in-malawi-s-option-b-hiv-prevention-of-mother-to-child-transmission-program-a-3-arm-cluster-randomized-controlled-trial-pure-malawi
#11
Sam Phiri, Hannock Tweya, Monique van Lettow, Nora E Rosenberg, Clement Trapence, Atupele Kapito-Tembo, Blessings Kaunda-Khangamwa, Florence Kasende, Virginia Kayoyo, Fabian Cataldo, Christopher Stanley, Salem Gugsa, Veena Sampathkumar, Erik Schouten, Levison Chiwaula, Michael Eliya, Frank Chimbwandira, Mina C Hosseinipour
BACKGROUND: Many sub-Saharan African countries have adopted Option B+, a prevention of mother-to-child transmission approach providing HIV-infected pregnant and lactating women with immediate lifelong antiretroviral therapy. High maternal attrition has been observed in Option B+. Peer-based support may improve retention. METHODS: A 3-arm stratified cluster randomized controlled trial was conducted in Malawi to assess whether facility- and community-based peer support would improve Option B+ uptake and retention compared with standard of care (SOC)...
June 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28493216/appropriateness-of-oral-anticoagulants-for-the-long-term-treatment-of-atrial-fibrillation-in-older-people-results-of-an-evidence-based-review-and-international-consensus-validation-process-oac-forta-2016
#12
REVIEW
Martin Wehling, Ronan Collins, Victor M Gil, Olivier Hanon, Roland Hardt, Martin Hoffmeister, Pedro Monteiro, Terence J Quinn, Dieter Ropers, Giuseppe Sergi, Freek W A Verheugt
BACKGROUND: Age appropriateness of anticoagulants for stroke prevention in atrial fibrillation is uncertain. OBJECTIVE: To review oral anticoagulants for the treatment of atrial fibrillation in older (age >65 years) people and to classify appropriate and inappropriate drugs based on efficacy, safety and tolerability using the Fit-fOR-The-Aged (FORTA) classification. METHODS: We performed a structured comprehensive review of controlled clinical trials and summaries of individual product characteristics to assess study and total patient numbers, quality of major outcome data and data of geriatric relevance...
May 10, 2017: Drugs & Aging
https://www.readbyqxmd.com/read/28472415/acupressure-for-frail-older-people-in-community-dwellings-a-randomised-controlled-trial
#13
Clara W C Chan, Pui Hing Chau, Angela Y M Leung, Kwai Ching Lo, Huafeng Shi, Tin Pui Yum, Yeuk Yiu Lee, Lei Li
Background: 'Frailty' is being increasing recognised as a geriatric syndrome of growing importance in the medical field. Acupressure is a non-pharmacological, non-invasive Traditional Chinese Medicine (TCM) treatment, which may serve to improve the quality of life (QOL) or prevent the progressive advancement of frailty in the aged population. Objective: to investigate the effects of a 12-week, TCM-principle guided acupressure intervention on the QOL of the frail older people living in the community...
May 2, 2017: Age and Ageing
https://www.readbyqxmd.com/read/28471944/geriatric-syndromes-new-frontiers-in-hiv-and-sarcopenia
#14
Kellie L Hawkins, Todd T Brown, Joseph B Margolick, Kristine M Erlandson
: HIV infection, in many circumstances, can now be managed as a chronic disease due to the marked increase in life expectancy since the introduction of combination antiretroviral therapy (ART). As the patients who first had access to combination ART age into their 50s and 60s, the effects of chronic HIV infection on health have become an important research focus in HIV infection. People living with HIV appear to exhibit an earlier occurrence of some aging-related conditions compared to people without HIV, in part due to higher rates of comorbidities, high-risk behaviors (e...
June 1, 2017: AIDS
https://www.readbyqxmd.com/read/28460128/inflamed-fat-and-mitochondrial-dysfunction-in-end-stage-renal-disease-links-to-hypoxia-could-curcumin-be-of-benefit
#15
Peter Stenvinkel, Volker H Haase
Inflamed adipose tissue and muscular mitochondrial dysfunction are linked and together these alterations may contribute to several sinister components of the uremic phenotype, such as muscle wasting, frailty, inflammation and dysfunctional adipose tissue with insulin resistance. Although the cause(s) of inflamed fat and mitochondrial dysfunction are likely multifactorial, tissue hypoxia may be an important player since hypoxia promote inflammatory processes and alter mitochondrial function. Among several transcription factors, hypoxia-inducible factor (HIF-1) play a prominent role in the adaption to hypoxia at the cellular level...
April 28, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28458530/frailty-syndrome-in-ambulatory-patients-with-copd
#16
Panita Limpawattana, Siraphong Putraveephong, Pratchaya Inthasuwan, Watchara Boonsawat, Daris Theerakulpisut, Jarin Chindaprasirt
Frailty is a state of increased risk of unfavorable outcomes when exposed to stressors, and COPD is one of the several chronic illnesses associated with the condition. However, few studies have been conducted regarding the prevalence of COPD and its related factors in Southeast Asia. The objectives of this study were to determine the prevalence of frailty in COPD patients and to identify the associated factors in these populations. A cross-sectional study of COPD patients who attended a COPD clinic was conducted from May 2015 to December 2016...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/28455830/the-iatrogenic-triad-polypharmacy-drug-drug-interactions-and-potentially-inappropriate-medications-in-older-adults
#17
Priscila Horta Novaes, Danielle Teles da Cruz, Alessandra Lamas Granero Lucchetti, Isabel Cristina Gonçalves Leite, Giancarlo Lucchetti
Background The elderly population is often in continuous use of several medications and is more subject to the "iatrogenic triad" of polypharmacy, potentially inappropriate medication use and drug-drug interactions. However, few studies have investigated these three factors concomitantly. Purpose To assess the prevalence and inter-relationship of potentially inappropriate medication (PIM) use, polypharmacy and drug-drug interactions in older adults, together with their associated factors. Setting city of Juiz de Fora, Brazil...
April 28, 2017: International Journal of Clinical Pharmacy
https://www.readbyqxmd.com/read/28451645/frailty-and-quality-of-life-in-adult-survivors-of-childhood-cancer
#18
Kirsten K Ness, Carrie R Howell, Kari L Bjornard
INTRODUCTION: Adult survivors of childhood cancer are at risk for frailty, a state of diminished physiologic reserve, typically seen in older adults, associated with morbidity and mortality. They are also at risk for poor quality of life. This review explores potential associations between frailty and quality of life and proposes potential interventions that may prevent or remediate frail health. AREAS COVERED AND LITERATURE SEARCH: A literature search using MEDLINE and EMBASE was undertaken using key words: childhood cancer survivors and each of the following: frailty, physical performance, emotional health, and quality of life...
2017: Expert Review of Quality of Life in Cancer Care
https://www.readbyqxmd.com/read/28449828/hypertension-canada-s-2017-guidelines-for-diagnosis-risk-assessment-prevention-and-treatment-of-hypertension-in-adults
#19
Alexander A Leung, Stella S Daskalopoulou, Kaberi Dasgupta, Kerry McBrien, Sonia Butalia, Kelly B Zarnke, Kara Nerenberg, Kevin C Harris, Meranda Nakhla, Lyne Cloutier, Mark Gelfer, Maxime Lamarre-Cliche, Alain Milot, Peter Bolli, Guy Tremblay, Donna McLean, Sheldon W Tobe, Marcel Ruzicka, Kevin D Burns, Michel Vallée, G V Ramesh Prasad, Steven E Gryn, Ross D Feldman, Peter Selby, Andrew Pipe, Ernesto L Schiffrin, Philip A McFarlane, Paul Oh, Robert A Hegele, Milan Khara, Thomas W Wilson, S Brian Penner, Ellen Burgess, Praveena Sivapalan, Robert J Herman, Simon L Bacon, Simon W Rabkin, Richard E Gilbert, Tavis S Campbell, Steven Grover, George Honos, Patrice Lindsay, Michael D Hill, Shelagh B Coutts, Gord Gubitz, Norman R C Campbell, Gordon W Moe, Jonathan G Howlett, Jean-Martin Boulanger, Ally Prebtani, Gregory Kline, Lawrence A Leiter, Charlotte Jones, Anne-Marie Côté, Vincent Woo, Janusz Kaczorowski, Luc Trudeau, Ross T Tsuyuki, Swapnil Hiremath, Denis Drouin, Kim L Lavoie, Pavel Hamet, Jean C Grégoire, Richard Lewanczuk, George K Dresser, Mukul Sharma, Debra Reid, Scott A Lear, Gregory Moullec, Milan Gupta, Laura A Magee, Alexander G Logan, Janis Dionne, Anne Fournier, Geneviève Benoit, Janusz Feber, Luc Poirier, Raj S Padwal, Doreen M Rabi
Hypertension Canada provides annually updated, evidence-based guidelines for the diagnosis, assessment, prevention, and treatment of hypertension. This year, we introduce 10 new guidelines. Three previous guidelines have been revised and 5 have been removed. Previous age and frailty distinctions have been removed as considerations for when to initiate antihypertensive therapy. In the presence of macrovascular target organ damage, or in those with independent cardiovascular risk factors, antihypertensive therapy should be considered for all individuals with elevated average systolic nonautomated office blood pressure (non-AOBP) readings ≥ 140 mm Hg...
May 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28449266/frailty-as-a-predictor-of-future-fracture-in-older-adults-a-systematic-review-and-meta-analysis
#20
Kuo-Wei Chen, Shu-Fang Chang, Pei-Ling Lin
BACKGROUND: Studies have identified frailty as an effective predictor of fracture; however, the correlation between frailty and fracture differs between various stages of frailty. OBJECTIVES: The main aim is to determine the correlation between various stages of frailty and fracture risk; a secondary purpose is to determine the correlation between subgroups (e.g., females, females with a hip fracture, or aged 65 years or older) within the stages of frailty and fracture risk...
April 27, 2017: Worldviews on Evidence-based Nursing
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