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Anatomy of the prostate

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https://www.readbyqxmd.com/read/28633957/displacement-patterns-of-stranded-i-125-seeds-after-permanent-brachytherapy-of-the-prostate-dosimetry-in-the-operating-room-put-into-perspective
#1
Marcel J Steggerda, Ferrie van den Boom, Thelma Witteveen, Luc M F Moonen
BACKGROUND AND PURPOSE: The reliability of post-implant dosimetry in the OR depends on the geometrical variability of implant and anatomy after the procedure. The purpose was to gain detailed information on seed displacement patterns in different sectors of the prostate. MATERIALS AND METHODS: Of 33 patients with stranded seed implants the seed geometry and the dose distribution were compared between the situation in the OR just after the procedure, based on ultrasound images, and the situation after 1month, based on registered CT and MR images...
June 17, 2017: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/28627007/optical-molecular-imaging-guided-radiation-therapy-part-1-integrated-x-ray-and-bioluminescence-tomography
#2
Junwei Shi, Thirupandiyur S Udayakumar, Zhiqun Wang, Nesrin Dogan, Alan Pollack, Yidong Yang
PURPOSE: X-ray CT faces challenges in differentiating tumors from surrounding healthy tissues. A bioluminescence tomography (BLT) system which can directly reconstruct the internal luminescent tumors, was developed and integrated with CT system to accurately guide radiation dose delivery. METHODS: The BLT system, employing a lens-coupled CCD camera, was physically registered with an onboard cone beam CT system in an image guided small animal arc radiation treatment system (iSMAART)...
June 19, 2017: Medical Physics
https://www.readbyqxmd.com/read/28590314/novel-imaging-in-advanced-prostate-cancer
#3
Hanan Goldberg, Robert J Hamilton
PURPOSE OF REVIEW: Prostate cancer (PCa) is the most commonly diagnosed noncutaneous cancer and second leading cause of death in men. Imaging evaluation of PCa is challenging because of the prostate's deep pelvic location, its complex zonal anatomy and its multifocal nature. Novel imaging modalities are needed to improve detection, reassessment in biochemical relapse, and disease progression in advanced metastatic stages. RECENT FINDINGS: Current imaging modalities have distinct strengths...
June 3, 2017: Current Opinion in Supportive and Palliative Care
https://www.readbyqxmd.com/read/28582632/prostate-cancer-a-correlative-study-of-multiparametric-mr-imaging-and-digital-histopathology
#4
Jin Tae Kwak, Sandeep Sankineni, Sheng Xu, Baris Turkbey, Peter L Choyke, Peter A Pinto, Vanessa Moreno, Maria Merino, Bradford J Wood
Purpose To correlate multiparametric magnetic resonance (MR) imaging and quantitative digital histopathologic analysis (DHA) of the prostate. Materials and Methods This retrospective study was approved by the local institutional review board and was HIPAA compliant. Forty patients (median age, 60 years; age range, 44-71 years) who underwent prostate MR imaging consisting of T2-weighted and diffusion-weighted (DW) MR imaging along with subsequent robot-assisted radical prostatectomy gave informed consent to be included...
June 5, 2017: Radiology
https://www.readbyqxmd.com/read/28579419/the-effect-of-catheter-displacement-and-anatomical-variations-on-the-dose-distribution-in-mri-guided-focal-hdr-brachytherapy-for-prostate-cancer
#5
Metha Maenhout, Jochem R N van der Voort van Zyp, Maxence Borot de Battisti, Max Peters, Marco van Vulpen, Maurice van den Bosch, Marinus A Moerland
PURPOSE: The aim of this study was to analyze the effect of catheter displacement and anatomical variations of prostate and organs at risk on dose distribution in MRI-guided 19 Gy single fraction focal high-dose-rate brachytherapy (HDR-BT) of the prostate. METHODS AND MATERIALS: Seventeen patients with localized prostate cancer were enrolled in a prospective trial investigating focal HDR-BT in a 1.5 T MRI-HDR-BT facility. The diagnostic MRI delineations were registered with intraoperative MR scan, and a single fraction of 19 Gy was applied to the visible tumor...
June 1, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28508252/anatomical-variants-in-prostate-artery-embolization-a-pictorial-essay
#6
Francisco Cesar Carnevale, Guilherme Rebello Soares, Andre Moreira de Assis, Airton Mota Moreira, Sardis Honoria Harward, Giovanni Guido Cerri
Prostate artery embolization (PAE) has emerged as a new treatment option for patients with symptomatic benign prostatic hyperplasia. The main challenges related to this procedure are navigating arteries with atherosclerosis and anatomical variations, and the potential risk of non-target embolization to pelvic structures due to the presence of collateral shunts and reflux of microparticles. Knowledge of classical vascular anatomy and the most common variations is essential for safe embolization, good clinical practice, and optimal outcomes...
May 15, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28501565/prostate-zonal-anatomy-correlates-with-the-detection-of-prostate-cancer-on-multiparametric-magnetic-resonance-imaging-ultrasound-fusion-targeted-biopsy-in-patients-with-a-solitary-pi-rads-v2-scored-lesion
#7
Jamil S Syed, Kevin A Nguyen, Cayce B Nawaf, Ansh M Bhagat, Steffen Huber, Angelique Levi, Peter Humphrey, Jeffrey C Weinreb, Peter G Schulam, Preston C Sprenkle
PURPOSE: To evaluate the positive predictive value (PPV) of the Prostate Imaging Reporting and Data System version 2 (PI-RADS v2) assessment method in patients with a single suspicious finding on prostate multiparametric magnetic resonance imaging (mpMRI). PATIENTS AND METHODS: A total of 176 patients underwent MRI/ultrasound fusion-targeted prostate biopsy after the detection of a single suspicious finding on mpMRI. The PPV for cancer detection was determined based on PI-RADS v2 assessment score and location...
May 10, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28482845/clinical-implementation-of-a-knowledge-based-planning-tool-for-prostate-vmat
#8
Richard Powis, Andrew Bird, Matthew Brennan, Susan Hinks, Hannah Newman, Katie Reed, John Sage, Gareth Webster
BACKGROUND: A knowledge based planning tool has been developed and implemented for prostate VMAT radiotherapy plans providing a target average rectum dose value based on previously achievable values for similar rectum/PTV overlap. The purpose of this planning tool is to highlight sub-optimal clinical plans and to improve plan quality and consistency. METHODS: A historical cohort of 97 VMAT prostate plans was interrogated using a RayStation script and used to develop a local model for predicting optimum average rectum dose based on individual anatomy...
May 8, 2017: Radiation Oncology
https://www.readbyqxmd.com/read/28447959/using-measurable-dosimetric-quantities-to-characterize-the-inter-structural-tradeoff-in-inverse-planning
#9
Hongcheng Liu, Peng Dong, Lei Xing
Traditional inverse planning relies on the use of weighting factors to balance the conflicting requirements of different structures. The manual trial-and-error determination of the weighting factors has long been recognized as a time-consuming part of treatment planning. The purpose of this work is to develop an inverse planning framework that parameterizes the dosimetric tradeoff among the structures with physically meaningful quantities to simplify the search for clinically sensible plans. In this formalism, instead of using the weighting factors, permissible variation range of the prescription dose or dose volume histogram (DVH) of the involved structures are used to characterize the "importance" of the structures...
April 27, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28345835/evolution-of-the-histo-epidemiological-profile-of-urological-cancers-in-togo
#10
Tchin Darré, Koué Folligan, Tchilabalo Matchonna Kpatcha, Kokou Kanassoua, Edoe Sewa, Sassil Daré, Kodjo Tengue, Koffi Amégbor, Gado Napo Koura
Background: Urological cancers are an important public health issue and pose problems with diagnosis and adequate management in developing countries. Our aim was to determine and report epidemiological and histological features of urological cancers in Togo. Materials and methods: A retrospective descriptive study was conducted of cases of urological cancers observed in the laboratory of pathological anatomy of the CHU Tokoin over the last 4 years (2012-2016). The parameters studied were frequency, age, sex, sites of development and histological type...
February 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28343953/development-and-validation-of-a-novel-and-cost-effective-animal-tissue-model-for-training-transurethral-resection-of-the-prostate
#11
Sichuan Hou, Gillian Ross, Iain Tait, Paul Halliday, Benjie Tang
OBJECTIVES: To develop and validate a new and cost-effective animal tissue training model for practicing resection skills of transurethral resection of the prostate (TURP). METHODS AND MATERIALS: A porcine kidney was prepared and restructured to simulate the relevant anatomy of the human prostate. The restructured prostate was connected to an artificial urethra and bladder. Face, content, and construct validity of the model was carried out using a 5-point Likert scale questionnaire, and comparison in task performance between participants and experts was made using observational clinical human reliability analysis...
March 23, 2017: Journal of Surgical Education
https://www.readbyqxmd.com/read/28338305/prostate-cancer-in-renal-transplant-recipients
#12
Benjamin A Sherer, Krishnan Warrior, Karl Godlewski, Martin Hertl, Oyedolamu Olaitan, Ajay Nehra, Leslie Allan Deane
As patients with end-stage renal disease are receiving renal allografts at older ages, the number of male renal transplant recipients (RTRs) being diagnosed with prostate cancer (CaP) is increasing. Historically, the literature regarding the management of CaP in RTR's is limited to case reports and small case series. To date, there are no standardized guidelines for screening or management of CaP in these complex patients. To better understand the unique characteristics of CaP in the renal transplant population, we performed a literature review of PubMed, without date limitations, using a combination of search terms including prostate cancer, end stage renal disease, renal transplantation, prostate cancer screening, prostate specific antigen kinetics, immunosuppression, prostatectomy, and radiation therapy...
March 24, 2017: International Braz J Urol: Official Journal of the Brazilian Society of Urology
https://www.readbyqxmd.com/read/28306555/assessment-of-dosimetric-impact-of-system-specific-geometric-distortion-in-an-mri-only-based-radiotherapy-workflow-for-prostate
#13
C Gustafsson, F Nordström, E Persson, J Brynolfsson, L E Olsson
Dosimetric errors in a magnetic resonance imaging (MRI) only radiotherapy workflow may be caused by system specific geometric distortion from MRI. The aim of this study was to evaluate the impact on planned dose distribution and delineated structures for prostate patients, originating from this distortion. A method was developed, in which computer tomography (CT) images were distorted using the MRI distortion field. The displacement map for an optimized MRI treatment planning sequence was measured using a dedicated phantom in a 3 T MRI system...
April 21, 2017: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/28297298/dosimetric-and-volumetric-changes-in-the-rectum-and-bladder-in-patients-receiving-cbct-guided-prostate-imrt-analysis-based-on-daily-cbct-dose-calculation
#14
David Pearson, Sukhdeep K Gill, Nina Campbell, Krishna Reddy
Delivered dose can be calculated by transferring the planned treatment beams onto the daily CBCT. Bladder and rectum volumetric doses were calculated and correlated to the daily bladder and rectum fullness. Patients for this study underwent hypofractionated prostate IMRT to 70 Gy in 28 fractions. Daily CBCT was utilized for image guidance. A clinically acceptable plan was created using a CTV-to-PTV uniform margin of 5 mm. Image fusion was performed to transfer the bladder and rectum contours onto each CBCT...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28297277/application-programming-in-c-environment-with-recorded-user-software-interactions-and-its-application-in-autopilot-of-vmat-imrt-treatment-planning
#15
Henry Wang, Lei Xing
An autopilot scheme of volumetric-modulated arc therapy (VMAT)/intensity-modulated radiation therapy (IMRT) planning with the guidance of prior knowledge is established with recorded interactions between a planner and a commercial treatment planning system (TPS). Microsoft (MS) Visual Studio Coded UI is applied to record some common planner-TPS interactions as subroutines. The TPS used in this study is a Windows-based Eclipse system. The interactions of our application program with Eclipse TPS are realized through a series of subroutines obtained by prerecording the mouse clicks or keyboard strokes of a planner in operating the TPS...
November 2016: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28291933/validation-of-rectal-sparing-throughout-the-course-of-proton-therapy-treatment-in-prostate-cancer-patients-treated-with-spaceoar-%C3%A2
#16
Samantha G Hedrick, Marcio Fagundes, Sara Case, Jackson Renegar, Marc Blakey, Mark Artz, Hao Chen, Ben Robison, Niek Schreuder
The purpose of this study was to investigate the consistency of rectal sparing using multiple periodic quality assurance computerized tomography imaging scans (QACT) obtained during the course of proton therapy for patients with prostate cancer treated with a hydrogel spacer. Forty-one low- and intermediate-risk prostate cancer patients treated with image-guided proton therapy with rectal spacer hydrogel were analyzed. To assess the reproducibility of rectal sparing with the hydrogel spacer, three to four QACTs were performed for each patient on day 1 and during weeks 1, 3, and 5 of treatment...
January 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28237429/prostate-mri-for-brachytherapists-anatomy-and-technique
#17
A M Venkatesan, R J Stafford, C Duran, P D Soni, A Berlin, P W McLaughlin
PURPOSE: To present an overview of mp MRI techniques necessary for high-resolution imaging of prostate. METHODS: We summarize examples from our clinical experience and concepts from the current literature that illustrate normal prostate anatomy on multiparametric MRI (mp MRI). RESULTS: Our experience regarding optimal mp MRI image acquisition is provided, as well as a summary of prostate and periprostatic anatomy and anatomical variants that pose challenges for BT...
February 23, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28220583/morphometric-analysis-of-prostate-zonal-anatomy-using-magnetic-resonance-imaging-mri-the-impact-on-age-related-changes-in-japanese-and-american-populations
#18
Toru Matsugasumi, Atsuko Fujihara, So Ushijima, Motohiro Kanazawa, Yasuhiro Yamada, Takumi Shiraishi, Fumiya Hongo, Kazumi Kamoi, Koji Okihara, Andre Luis de Castro Abreu, Masakatsu Oishi, Toshitaka Shin, Suzanne Palmer, Inderbir S Gill, Osamu Ukimura
OBJECTIVES: Magnetic resonance imaging (MRI) can be used to reliably evaluate prostate zonal anatomy. Objectives of this study was to evaluate the impact of morphometric MRI analysis of the prostate zonal anatomy on aging, prostatic hypertrophy, and lower urinary tract symptoms in patients from Japan and the USA. SUBJECTS AND METHODS: A retrospective analysis of 307 men, including Japanese (n=156) and American (n=151) patients, who consecutively underwent 3-Tesla MRI and International Prostate Symptom Score (IPSS) due to elevated PSA...
February 20, 2017: BJU International
https://www.readbyqxmd.com/read/28197655/prefraction-displacement-and-intrafraction-drift-of-the-prostate-due%C3%A2-to-perineal-ultrasound-probe-pressure
#19
Minglun Li, Nina-Sophie Hegemann, Farkhad Manapov, Anne Kolberg, Patrick Dominik Thum, Ute Ganswindt, Claus Belka, Hendrik Ballhausen
OBJECTIVE: In image-guided EBRT of the prostate, transperineal ultrasound (US) probes exert pressure on the perineum both during planning and treatment. Through tissue deformation and relaxation, this causes target and risk organ displacement and drift. In this study, prefraction shift and intrafraction drift of the prostate are quantified during robotic transperineal 4DUS. METHODS: The position of the prostate was recorded for different positions of the probe before treatment in 10 patients (16 series of measurements)...
February 14, 2017: Strahlentherapie und Onkologie: Organ der Deutschen Röntgengesellschaft ... [et Al]
https://www.readbyqxmd.com/read/28169182/reproductive-disorders-of-marsupials
#20
REVIEW
Cathy A Johnson-Delaney, Angela M Lennox
Marsupial reproduction differs significantly in anatomy and physiology from that of placental mammals. The gastrointestinal and urogenital tracts empty into a cloaca. Reproductive parameters include gestation and pouch time, as the fetus develops outside of the uterus. Captive marsupials discussed include sugar gliders), short-tailed opossums, Virginia opossums, and Tammar and Bennett's wallabies. Common disease conditions include joey eviction, pouch infections, mastitis, metritis, prostatitis, penile necrosis, and neoplasia...
May 2017: Veterinary Clinics of North America. Exotic Animal Practice
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