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poly-unsaturated fatty acids

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https://www.readbyqxmd.com/read/28107709/quantification-of-fatty-acids-in-the-muscle-of-antarctic-fish-trematomus-bernacchii-by-gas-chromatography-mass-spectrometry-optimization-of-the-analytical-methodology
#1
C Truzzi, S Illuminati, A Annibaldi, M Antonucci, G Scarponi
This work presents data on the quantification of fatty acids (FAs, in terms of mass unit per tissue weight) in the muscle of Trematomus bernacchii, a key species in Antarctica, often used as bioindicator for contamination studies. Modifications in fatty acids content should be considered a useful biomarker to study how contaminants affect Antarctic biota. Until now, very few studies quantified fatty acids of muscle of T. bernacchii, and only as percentage of a single fatty acid on total lipids. To perform the quantification of fatty acids, we used an analytical method based on a fast microwave-assisted extraction of lipids from a lyophilized sample, a base-catalyzed trans-esterification of lipid extract to obtain Fatty Acids Methyl Esters (FAMEs), and a separation and identification of FAMEs by gas chromatography-mass spectrometry...
December 31, 2016: Chemosphere
https://www.readbyqxmd.com/read/28103845/maternal-intake-of-seafood-and-supplementary-long-chain-n-3-poly-unsaturated-fatty-acids-and-preterm-delivery
#2
Anne Lise Brantsæter, Linda Englund-Ögge, Margareta Haugen, Bryndis Eva Birgisdottir, Helle Katrine Knutsen, Verena Sengpiel, Ronny Myhre, Jan Alexander, Roy M Nilsen, Bo Jacobsson, Helle Margrete Meltzer
BACKGROUND: Preterm delivery increases the risk of neonatal morbidity and mortality. Studies suggest that maternal diet may affect the prevalence of preterm delivery. The aim of this study was to assess whether maternal intakes of seafood and marine long chain n-3 polyunsaturated fatty acids (LCn-3PUFA) from supplements were associated with preterm delivery. METHODS: The study population included 67,007 women from the Norwegian Mother and Child Cohort Study. Maternal food and supplement intakes were assessed by a validated self-reported food frequency questionnaire in mid-pregnancy...
January 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28046759/su-f-i-64-comparison-of-lipid-contents-using-steam-and-press-with-in-vivo-high-resolution-spectra-at-9-4-t
#3
K-H Song, S-I Lim, C-H Yoo, B-Y Choe
PURPOSE: The objective of this study is to compare lipid contents using localized point-resolved spectroscopy (PRESS) and stimulated echo acquisition mode (STEAM) sequences to assess lipid resonances in the liver, using in vivo high-resolution spectra at 9.4 T. METHODS: The examinations were performed on a Bruker 9.4T scanner using 4-channel animal coil for higher resolution. We used PRESS (repetition time [TR]/ TE = 3500/20 ms; number of signal averages [NSA] = 128; acquisition data points = 2048) and STEAM (TR/TM/TE = 3500/10/20 ms; NSA = 128; acquisition data points = 2048)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28027401/breast-milk-poly-unsaturated-fatty-acids-associations-with-adolescent-allergic-disease-and-lung-function
#4
Nilakshi T Waidyatillake, Rachel Stoney, Francis Thien, Caroline J Lodge, Julie A Simpson, Katrina J Allen, Michael J Abramson, Bircan Erbas, Cecile Svanes, Shyamali C Dharmage, Adrian J Lowe
BACKGROUND: It has been hypothesised that n-3 PUFA in breast-milk may assist immune and lung development. There are very limited data on possible long-term effects on allergic disease and lung function. The aim was to investigate associations of n-3 and n-6 PUFA levels in colostrum and breast milk with allergic disease and lung function at ages 12 and 18 years. METHOD: PUFAs were measured in 194 colostrum samples and in 118 three month expressed breast milk samples from mothers of children enrolled in the Melbourne Atopy Cohort (MACS) Study, a high risk birth cohort study...
December 27, 2016: Allergy
https://www.readbyqxmd.com/read/27973561/cross-classification-of-human-urinary-lipidome-by-sex-age-and-body-mass-index
#5
Kazuo Okemoto, Keiko Maekawa, Yoko Tajima, Masahiro Tohkin, Yoshiro Saito
Technological advancements in past decades have led to the development of integrative analytical approaches to lipidomics, such as liquid chromatography-mass spectrometry (LC/MS), and information about biogenic lipids is rapidly accumulating. Although several cohort-based studies have been conducted on the composition of urinary lipidome, the data on urinary lipids cross-classified by sex, age, and body mass index (BMI) are insufficient to screen for various abnormalities. To promote the development of urinary lipid metabolome-based diagnostic assay, we analyzed 60 urine samples from healthy white adults (young (c...
2016: PloS One
https://www.readbyqxmd.com/read/27919272/enhanced-lipid-and-biomass-production-by-a-newly-isolated-and-identified-marine-microalga
#6
Mouna Dammak, Sandra Mareike Haase, Ramzi Miladi, Faten Ben Amor, Mohamed Barkallah, David Gosset, Chantal Pichon, Bernhard Huchzermeyer, Imen Fendri, Michel Denis, Slim Abdelkafi
BACKGROUND: The increasing demand for microalgae lipids as an alternative to fish has encouraged researchers to explore oleaginous microalgae for food uses. In this context, optimization of growth and lipid production by the marine oleaginous V2-strain-microalgae is of great interest as it contains large amounts of mono-unsaturated (MUFAs) and poly-unsaturated fatty acids (PUFAs). METHODS: In this study, the isolated V2 strain was identified based on 23S rRNA gene...
December 5, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27905210/erythrocyte-fatty-acid-composition-does-not-influence-levels-of-free-bioavailable-and-total-25-hydroxy-vitamin-d
#7
Martin Carlsson, Ingela Nilsson, Lars Brudin, Siv-Ping Von, Pär Wanby
In vitro, mono- and polyunsaturated fatty acids (FAs) may decrease the binding affinity of vitamin D metabolites for vitamin D-binding protein, which in turn may influence their bioavailability. FAs incorporated as phospholipids in erythrocyte (ery-) cell membranes reflect dietary intake. The purpose of this study was to investigate ery-FA composition in relation to markers for vitamin D. In healthy females (age 22.6 ± 2.0 years) total 25(OH)D was measured by LC-MS/MS (n = 78), free 25(OH)D with ELISA (n = 64 of 78), and bioavailable 25(OH)D was calculated...
February 2017: Scandinavian Journal of Clinical and Laboratory Investigation
https://www.readbyqxmd.com/read/27883264/mucosa-associated-biohydrogenating-microbes-protect-the-simulated-colon-microbiome-from-stress-associated-with-high-concentrations-of-poly-unsaturated-fat
#8
Rosemarie De Weirdt, Emma Hernandez-Sanabria, Veerle Fievez, Eva Mees, Annelies Geirnaert, Florence Van Herreweghen, Ramiro Vilchez-Vargas, Pieter Van den Abbeele, Ruy Jauregui, Dietmar H Pieper, Bruno Vlaeminck, Tom Van de Wiele
Polyunsaturated fatty acids (PUFAs) may affect colon microbiome homeostasis by exerting (specific) antimicrobial effects and/or interfering with mucosal biofilm formation at the gut mucosal interface. We used standardized batch incubations and the Mucosal-Simulator of the Human Microbial Intestinal Ecosystem (M-SHIME) to show the in vitro luminal and mucosal effects of the main PUFA in the Western diet, linoleic acid (LA). High concentrations of LA were found to decrease butyrate production and Faecalibacterium prausnitzii numbers dependent on LA biohydrogenation to vaccenic acid (VA) and stearic acid (SA)...
November 24, 2016: Environmental Microbiology
https://www.readbyqxmd.com/read/27864649/cardioprotective-effects-of-omega-3-fatty-acids-origin-of-the-variability
#9
Jérôme Roy, Jean-Yves Le Guennec
Since 40 years, it is known that omega-3 poly-unsaturated fatty acids (ω3 PUFAs) have cardioprotective effects. These include antiarrhythmic effects, improvements of autonomic function, endothelial function, platelet anti-aggregation and inflammatory properties, lowering blood pressure, plaque stabilization and reduced atherosclerosis. However, recently, conflicting results regarding the health benefits of ω3 PUFAs from seafood or ω3 PUFAs supplements have emerged. The aim of this review is to examine recent literature regarding health aspects of ω3 PUFAs intake from fish or supplements, and to discuss different arguments/reasons supporting these conflicting findings...
November 18, 2016: Journal of Muscle Research and Cell Motility
https://www.readbyqxmd.com/read/27834334/comparison-of-dietary-profile-of-a-rural-south-indian-population-with-the-current-dietary-recommendations-for-prevention-of-non-communicable-diseases-cures-147
#10
Narasimhan Sowmya, Nagarajan Lakshmipriya, Kokila Arumugam, Sivasankari Venkatachalam, Parthasarathy Vijayalakshmi, Vaidya Ruchi, Gunasekaran Geetha, Ranjit Mohan Anjana, Viswanathan Mohan, Kamala Krishnaswamy, Vasudevan Sudha
BACKGROUND & OBJECTIVES: Despite the rising prevalence of non-communicable diseases (NCDs) in rural India, data on the dietary profile of the rural Indian population in relation to the recommendations for prevention of NCDs are scarce. This study was conducted to assess the dietary intake of a rural south Indian population in relation to the current dietary recommendations for the prevention of NCDs. METHODS: The dietary profiles of 6907 adults aged ≥ 20 yr, from a cluster of 42 villages in Kancheepuram district of Tamil Nadu State in southern India, were assessed using a validated food frequency questionnaire...
July 2016: Indian Journal of Medical Research
https://www.readbyqxmd.com/read/27827396/fatty-acid-intake-and-its-dietary-sources-in-relation-with-markers-of-type-2-diabetes-risk-the-neo-study
#11
A J Wanders, M Alssema, E J P de Koning, S le Cessie, J H de Vries, P L Zock, F R Rosendaal, M den Heijer, R de Mutsert
OBJECTIVE: The aim of this study was to examine the relations between intakes of total, saturated, mono-unsaturated, poly-unsaturated and trans fatty acids (SFA, MUFA, PUFA and TFA), and their dietary sources (dairy, meat and plant) with markers of type 2 diabetes risk. SUBJECTS/METHODS: This was a cross-sectional analysis of baseline data of 5675 non-diabetic, middle-aged participants of the Netherlands Epidemiology of Obesity (NEO) study. Associations between habitual dietary intake and fasting and postprandial blood glucose and insulin, Homeostatic Model Assessment of Insulin Resistance (HOMA-IR), HOMA of β-cell function (HOMA-B) and Disposition Index were assessed through multivariable linear regression models with adjustments for demographic, lifestyle and dietary factors...
November 9, 2016: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27790483/effect-of-poly-unsaturated-fatty-acids-administration-on-children-with-attention-deficit-hyperactivity-disorder-a-randomized-controlled-trial
#12
Puneet Anand, Ankur Sachdeva
INTRODUCTION: Attention Deficit Hyperactivity Disorder (ADHD) is a common disorder of childhood. Studies have indicated nutritional deficiencies, particularly Poly Unsaturated Fatty Acids (PUFA) deficiency in these children and have suggested supplementation with PUFA for clinical improvement. AIM: The present study aimed at evaluating the effect of PUFA administration in Indian children with ADHD. SETTINGS AND DESIGN: The study was conducted in the paediatrics and psychiatry departments of a tertiary care hospital...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27787742/-18-f-fluorocholine-pet-ct-imaging-of-liver-cancer-radiopathologic-correlation-with-tissue-phospholipid-profiling
#13
Sandi A Kwee, Miles M Sato, Yu Kuang, Adrian Franke, Laurie Custer, Kyle Miyazaki, Linda L Wong
PURPOSE: [(18)F]fluorocholine PET/CT can detect hepatocellular carcinoma (HCC) based on imaging the initial steps of phosphatidylcholine synthesis. To relate the diagnostic performance of [(18)F]fluorocholine positron emission tomography (PET)/x-ray computed tomography (CT) to the phospholipid composition of liver tumors, radiopathologic correspondence was performed in patients with early-stage liver cancer who had undergone [(18)F]fluorocholine PET/CT before tumor resection. PROCEDURES: Tumor and adjacent liver were profiled by liquid chromatography mass spectrometry, quantifying phosphatidylcholine species by mass-to-charge ratio...
October 27, 2016: Molecular Imaging and Biology: MIB: the Official Publication of the Academy of Molecular Imaging
https://www.readbyqxmd.com/read/27693805/role-of-dietary-fatty-acids-in-liver-injury-caused-by-vinyl-chloride-metabolites-in-mice
#14
Lisanne C Anders, Heegook Yeo, Brenna R Kaelin, Anna L Lang, Adrienne M Bushau, Amanda N Douglas, Matt Cave, Gavin E Arteel, Craig J McClain, Juliane I Beier
BACKGROUND: Vinyl chloride (VC) causes toxicant-associated steatohepatitis at high exposure levels. Recent work by this group suggests that underlying liver disease may predispose the liver to VC hepatotoxicity at lower exposure levels. The most common form of underlying liver disease in the developed world is non-alcoholic fatty liver disease (NAFLD). It is well-known that the type of dietary fat can play an important role in the pathogenesis of NAFLD. However, whether the combination of dietary fat and VC/metabolites promotes liver injury has not been studied...
November 15, 2016: Toxicology and Applied Pharmacology
https://www.readbyqxmd.com/read/27663185/docosahexaenoyl-serotonin-an-endogenously-formed-n-3-fatty-acid-serotonin-conjugate-has-anti-inflammatory-properties-by-attenuating-il-23-il-17-signaling-in-macrophages
#15
Mieke Poland, Jean Paul Ten Klooster, Zheng Wang, Raymond Pieters, Mark Boekschoten, Renger Witkamp, Jocelijn Meijerink
Conjugates of fatty acids and amines, including endocannabinoids, are known to play important roles as endogenous signaling molecules. Among these, the ethanolamine conjugate of the n-3 poly unsaturated long chain fatty acid (PUFA) docosahexaenoic acid (22:6n-3) (DHA) was shown to possess strong anti-inflammatory properties. Previously, we identified the serotonin conjugate of DHA, docosahexaenoyl serotonin (DHA-5-HT), in intestinal tissues and showed that its levels are markedly influenced by intake of n-3 PUFAs...
December 2016: Biochimica et Biophysica Acta
https://www.readbyqxmd.com/read/27640518/inflammation-in-depression-and-the-potential-for-anti-inflammatory-treatment
#16
REVIEW
Ole Kohler, Jesper Krogh, Ole Mors, Michael Eriksen Benros
Accumulating evidence supports an association between depression and inflammatory processes, a connection that seems to be bidirectional. Clinical trials have indicated antidepressant treatment effects for anti-inflammatory agents, both as add-on treatment and as monotherapy. In particular, nonsteroidal anti-inflammatory drugs (NSAIDs) and cytokine-inhibitors have shown antidepressant treatment effects compared to placebo, but also statins, poly-unsaturated fatty acids, pioglitazone, minocycline, modafinil, and corticosteroids may yield antidepressant treatment effects...
2016: Current Neuropharmacology
https://www.readbyqxmd.com/read/27578132/poly-is-more-effective-than-monounsaturated-fat-for-dietary-management-in-the-metabolic-syndrome-the-muffin-study
#17
Michael Miller, John D Sorkin, Laura Mastella, Aimee Sutherland, Jeffrey Rhyne, Patrick Donnelly, Kathy Simpson, Andrew P Goldberg
BACKGROUND: The metabolic syndrome (MetS) is highly prevalent and associated with an increased risk for type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). Lifestyle recommendations to treat MetS often include the replacement of saturated fats (SFAs) and monosaccharides with unsaturated fat. However, it is unclear whether metabolic parameters will improve more when the saturated fat in American Heart Association (AHA) diets is replaced with higher concentrations of monounsaturated or polyunsaturated fatty acids (MUFA or PUFA)...
July 2016: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/27529331/nutrient-patterns-and-their-relationship-to-metabolic-syndrome-in-iranian-adults
#18
Sayyed Saeid Khayyatzadeh, Mohsen Moohebati, Mohsen Mazidi, Amir Avan, Maryam Tayefi, Seyed Mohammad Reza Parizadeh, Mahmoud Ebrahimi, Alireza Heidari-Bakavoli, Mahmoud Reza Azarpazhooh, Habibollah Esmaily, Gordon A Ferns, Mohsen Nematy, Mohammad Safarian, Majid Ghayour-Mobarhan
BACKGROUND: The prevalence of metabolic syndrome (MetS) is increasing globally. It is associated with a significant risk of developing type 2 diabetes mellitus and cardiovascular disease. MATERIALS AND METHODS: The relationship between adherence to several different dietary patterns and the presence of MetS was explored in an Iranian population sample of 5764 subjects. RESULTS: We observed that the prevalence of MetS was 13% and 18% in men and women, respectively...
October 2016: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27501784/dietary-fats-and-oils-in-india
#19
Seema Gulati, Anoop Misra, Meenu Sharma
Background India is undergoing rapid nutrition transition concurrent with increase in obesity, metabolic syndrome, and type 2 diabetes (T2DM). From a healthy traditional home-cooked high-fiber, low-fat, low-calorie diet, there is a shift towards increasing consumption of packaged, ready-to-eat foods which are calorie-dense and contain refined carbohydrates, high fat, salt and sugar and less fiber. Although fats and oils have been an integral part of our diets, there is a change in the pattern of consumption, in terms of both quality and quantity...
August 11, 2016: Current Diabetes Reviews
https://www.readbyqxmd.com/read/27494106/light-intensity-impacts-the-production-of-biofuel-intermediates-in-heterosigma-akashiwo-growing-on-simulated-flue-gas-containing-carbon-dioxide-and-nitric-oxide
#20
Colleen M Bianco, Jennifer J Stewart, Katherine R Miller, Catherine Fitzgerald, Kathryn J Coyne
As a potential biofuel feedstock, the marine microalga, Heterosigma akashiwo, accumulates significant lipids, is capable of long-term growth in outdoor photobioreactors, and is an excellent candidate for the bioremediation of industrial emissions. Here, we evaluated resource partitioning in H. akashiwo growing on a CO2 and NO gas mixture under three light intensities: 160, 560, or 1200μmolquantam(-2)s(-1). Light levels had no effect on growth; however, cultures in high light accumulated 2.3-fold more carbohydrates and 17% fewer lipids...
November 2016: Bioresource Technology
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