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poly-unsaturated fatty acids

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https://www.readbyqxmd.com/read/28390301/mercury-exposure-serum-antinuclear-antibodies-and-serum-cytokine-levels-in-the-long-island-study-of-seafood-consumption-a-cross-sectional-study-in-ny-usa
#1
Rebecca N Monastero, Roxanne Karimi, Jennifer F Nyland, James Harrington, Keith Levine, Jaymie R Meliker
Mercury (Hg) is a well-known neurotoxin, and has been more recently studied specifically as an immunotoxin. In experimental and a few epidemiologic studies, Hg has been associated with distinct cytokine profiles and antinuclear antibody (ANA) positivity, though patterns at lower levels of exposure, typical of seafood consumers with a western diet, are not well characterized. Seafood consumers (n=287) recruited on Long Island, NY completed food frequency and health questionnaires and provided blood for analysis of Hg, poly-unsaturated fatty acids (omega-3 and omega-6 fatty acids), selenium (Se), ANA, and several cytokines (IL-1β, IL-4, IL-10, TNF-α, IL-17, IFN-γ, and IL-1ra)...
April 5, 2017: Environmental Research
https://www.readbyqxmd.com/read/28388313/arachidonic-acid-and-docosahexanoic-acid-enhance-platelet-formation-from-human-apheresis-derived-cd34-cells
#2
Ankita Dhenge, Kedar Limbkar, Sameer Melinkeri, Vaijayanti Prakash Kale, Lalita Limaye
An Aberration in megakaryopoiesis and thrombopoiesis, 2 important processes that maintain hemostasis, leads to thrombocytopenia. Though platelet transfusions are used to treat this condition, blood banks frequently face a shortage of platelets. Therefore, methods to generate platelets on a large scale are strongly desirable. However, to generate megakaryocytes (MKs) and platelets (PLTs) in numbers sufficient for clinical application, it is essential to understand the mechanism of platelet production and explore efficient strategies accordingly...
April 7, 2017: Cell Cycle
https://www.readbyqxmd.com/read/28351404/longitudinal-10-year-changes-in-dietary-intake-and-associations-with-cardio-metabolic-risk-factors-in-the-northern-sweden-health-and-disease-study
#3
Anna Winkvist, Sofia Klingberg, Lena Maria Nilsson, Maria Wennberg, Frida Renström, Göran Hallmans, Kurt Boman, Ingegerd Johansson
BACKGROUND: Dietary risks today constitute the largest proportion of disability-adjusted life years (DALYs) globally and in Sweden. An increasing number of people today consume highly processed foods high in saturated fat, refined sugar and salt and low in dietary fiber, vitamins and minerals. It is important that dietary trends over time are monitored to predict changes in disease risk. METHODS: In total, 15,995 individuals with two visits 10 (±1) years apart in the population-based Västerbotten Intervention Programme 1996-2014 were included...
March 28, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/28265702/from-current-algae-products-to-future-biorefinery-practices-a-review
#4
Michel H M Eppink, Giuseppe Olivieri, Hans Reith, Corjan van den Berg, Maria J Barbosa, Rene H Wijffels
Microalgae are considered to be one of the most promising next generation bio-based/food feedstocks with a unique lipid composition, high protein content, and an almost unlimited amount of other bio-active molecules. High-value components such as the soluble proteins, (poly) unsaturated fatty acids, pigments, and carbohydrates can be used as an important ingredient for several markets, such as the food/feed/chemical/cosmetics and health industries. Although cultivation costs have decreased significantly in the last few decades, large microalgae production processes become economically viable if all complex compounds are optimally valorized in their functional state...
March 7, 2017: Advances in Biochemical Engineering/biotechnology
https://www.readbyqxmd.com/read/28254293/high-fluorescence-emission-silver-nano-particles-coated-with-poly-styrene-g-soybean-oil-graft-copolymers-antibacterial-activity-and-polymerization-kinetics
#5
Baki Hazer, Özlem A Kalaycı
Autoxidation of poly unsaturated fatty acids makes negative effect on foods. In this work, this negative effect was turned to a great advantage using autoxidized soybean oil as a macroperoxide nanocomposite initiator containing silver nano particles in free radical polymerization of vinyl monomers. The synthesis of soybean oil macro peroxide was carried out by exposing soybean oil to air oxygen with the presence of silver nanoparticles (Ag NPs) at room temperature. Autoxidized soybean oil macroperoxide containing silver nanoparticles (Agsbox) successfully initiated the free radical polymerization of styrene in order to obtain Polystyrene (PS)-g-soybean oil graft copolymer containing Ag NPs...
May 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28242935/trans-himalayan-rhodiola-imbricata-edgew-root-a-novel-source-of-dietary-amino-acids-fatty-acids-and-minerals
#6
Amol B Tayade, Priyanka Dhar, Jatinder Kumar, Manu Sharma, Om P Chaurasia, Ravi B Srivastava
Roots of Rhodiola imbricata Edgew from Indian trans-Himalayan cold desert known for their nutritional and medicinal attributes were evaluated for the dietary amino acids, fatty acids and mineral composition. Nine essential and twelve non-essential amino acids were quantified. The contents ranged between 91.33 and 1640.67 µg/g. Histidine (1434.33 µg/g), lysine (1329.33 µg/g) and threonine (1015.67 μg/g) were dominant essential amino acids, while glycine (1640.67 µg/g), proline (1263.67 µg/g), alanine (1142...
February 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/28237087/e-configuration-structures-of-epa-and-dha-derived-from-euphausia-superba-and-their-significant-inhibitive-effects-on-growth-of-human-cancer-cell-lines-in-vitro
#7
Weilong Zheng, Xudong Wang, Wenjing Cao, Bowen Yang, Ying Mu, Yuesheng Dong, Zhilong Xiu
Many bioactive components such as poly-unsaturated fatty acids (e.g. EPA and DHA), phospholipids and astaxanthin are known in Antarctic krill (Euphausia superba) oil. The krill DHA and EPA are generally considered to be similar to natural ones. However, two chemical compounds which were separated from Antarctic krill oil and identified as EPA and DHA by HRESIMS and NMR acted much more effective inhibitive activities on growth of several cell lines (U937, K562, SMMC-7721, PC-3, MDA-MB-231, HL60 and MCF-7) than those from sturgeon liver and commercial fish oil...
February 2017: Prostaglandins, Leukotrienes, and Essential Fatty Acids
https://www.readbyqxmd.com/read/28216958/-1-h-nmr-based-serum-metabolomics-reveals-erythromycin-induced-liver-toxicity-in-albino-wistar-rats
#8
Atul Rawat, Durgesh Dubey, Anupam Guleria, Umesh Kumar, Amit K Keshari, Swati Chaturvedi, Anand Prakash, Sudipta Saha, Dinesh Kumar
INTRODUCTION: Erythromycin (ERY) is known to induce hepatic toxicity which mimics other liver diseases. Thus, ERY is often used to produce experimental models of drug-induced liver-toxicity. The serum metabolic profiles can be used to evaluate the liver-toxicity and to further improve the understanding of underlying mechanism. OBJECTIVE: To establish the serum metabolic patterns of Erythromycin induced hepatotoxicity in albino wistar rats using (1)H NMR based serum metabolomics...
October 2016: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/28215784/comparison-of-derivatization-ionization-techniques-for-liquid-chromatography-tandem-mass-spectrometry-analysis-of-oxylipins
#9
Sven W Meckelmann, Stefan Hellhake, Maryvonne Steuck, Michael Krohn, Nils Helge Schebb
The performance of two derivatization and ionization techniques for the quantitative reversed phase liquid chromatography (LC)- mass spectrometry (MS) analysis of hydroxy fatty acids (OH-PUFA) in plasma was evaluated: One used AMPP (N-(4-aminomethylphenyl)pyridinium chloride) leading to a positive charged amid-derivate which can be detected by electrospray ionization (ESI)-MS. Second yielded penta fluorobenzyl bromide (PFB) ester derivates allowing detection in electron capture atmospheric pressure chemical ionization (ecAPCI)-MS...
February 17, 2017: Prostaglandins & Other Lipid Mediators
https://www.readbyqxmd.com/read/28187761/erratum-to-maternal-intake-of-seafood-and-supplementary-long-chain-n-3-poly-unsaturated-fatty-acids-and-preterm-delivery
#10
Anne Lise Brantsæter, Linda Englund-Ögge, Margareta Haugen, Bryndis Eva Birgisdottir, Helle Katrine Knutsen, Verena Sengpiel, Ronny Myhre, Jan Alexander, Roy M Nilsen, Bo Jacobsson, Helle Margrete Meltzer
No abstract text is available yet for this article.
February 10, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28121994/diet-and-adhd-reviewing-the-evidence-a-systematic-review-of-meta-analyses-of-double-blind-placebo-controlled-trials-evaluating-the-efficacy-of-diet-interventions-on-the-behavior-of-children-with-adhd
#11
Lidy M Pelsser, Klaas Frankena, Jan Toorman, Rob Rodrigues Pereira
INTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is a debilitating mental health problem hampering the child's development. The underlying causes include both genetic and environmental factors and may differ between individuals. The efficacy of diet treatments in ADHD was recently evaluated in three reviews, reporting divergent and confusing conclusions based on heterogeneous studies and subjects. To address this inconsistency we conducted a systematic review of meta-analyses of double-blind placebo-controlled trials evaluating the effect of diet interventions (elimination and supplementation) on ADHD...
2017: PloS One
https://www.readbyqxmd.com/read/28115966/the-effect-of-walnut-oil-consumption-on-blood-sugar-in-patients-with-diabetes-mellitus-type-2
#12
Mohammadjavad Zibaeenezhad, Kamran Aghasadeghi, Hossein Hakimi, Hassan Yarmohammadi, Farzad Nikaein
BACKGROUND: Prevalence of diabetes mellitus type 2 (DM) is increasing globally. Considering the potential role of poly-unsaturated fatty acids in prevention of DM type 2 and lipid profiles improvement, some studies have been carried out on walnut. However, there are no studies on control of blood sugar in DM type 2 patients using walnut. OBJECTIVES: The current study aimed to evaluate the effect of walnut oil on blood sugar in DM type 2 patients. METHODS: This randomized control clinical trial was performed on 100 patients with DM type 2...
July 2016: International Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28107816/the-time-course-of-erythrocyte-membrane-fatty-acid-concentrations-during-and-after-treatment-of-non-human-primates-with-increasing-doses-of-an-omega-3-rich-phospholipid-preparation-derived-from-krill-oil
#13
Petter-Arnt Hals, Xiaoli Wang, Fabiana Piscitelli, Vincenzo Di Marzo, Yong-Fu Xiao
BACKGROUND: A commonly used measure to reflect the intake of the long-chain omega-3 fatty acids EPA and DHA is the omega-3 index, defined as the sum of EPA + DHA as % of total fatty acids in erythrocyte membrane. When the omega-3 index changes it follows that the relative fractions of other fatty acids in the membrane are also changed. In the present study, increasing doses of a preparation of omega-3 rich phospholipids extracted from krill oil were administered orally to non-human primates for 12 weeks and the time course of EPA, DHA and 22 other fatty acids in erythrocytes was determined bi-weekly during treatment and for 8 weeks after cessation of treatment...
January 21, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28107709/quantification-of-fatty-acids-in-the-muscle-of-antarctic-fish-trematomus-bernacchii-by-gas-chromatography-mass-spectrometry-optimization-of-the-analytical-methodology
#14
C Truzzi, S Illuminati, A Annibaldi, M Antonucci, G Scarponi
This work presents data on the quantification of fatty acids (FAs, in terms of mass unit per tissue weight) in the muscle of Trematomus bernacchii, a key species in Antarctica, often used as bioindicator for contamination studies. Modifications in fatty acids content should be considered a useful biomarker to study how contaminants affect Antarctic biota. Until now, very few studies quantified fatty acids of muscle of T. bernacchii, and only as percentage of a single fatty acid on total lipids. To perform the quantification of fatty acids, we used an analytical method based on a fast microwave-assisted extraction of lipids from a lyophilized sample, a base-catalyzed trans-esterification of lipid extract to obtain Fatty Acids Methyl Esters (FAMEs), and a separation and identification of FAMEs by gas chromatography-mass spectrometry...
April 2017: Chemosphere
https://www.readbyqxmd.com/read/28103845/maternal-intake-of-seafood-and-supplementary-long-chain-n-3-poly-unsaturated-fatty-acids-and-preterm-delivery
#15
Anne Lise Brantsæter, Linda Englund-Ögge, Margareta Haugen, Bryndis Eva Birgisdottir, Helle Katrine Knutsen, Verena Sengpiel, Ronny Myhre, Jan Alexander, Roy M Nilsen, Bo Jacobsson, Helle Margrete Meltzer
BACKGROUND: Preterm delivery increases the risk of neonatal morbidity and mortality. Studies suggest that maternal diet may affect the prevalence of preterm delivery. The aim of this study was to assess whether maternal intakes of seafood and marine long chain n-3 polyunsaturated fatty acids (LCn-3PUFA) from supplements were associated with preterm delivery. METHODS: The study population included 67,007 women from the Norwegian Mother and Child Cohort Study. Maternal food and supplement intakes were assessed by a validated self-reported food frequency questionnaire in mid-pregnancy...
January 19, 2017: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/28046759/su-f-i-64-comparison-of-lipid-contents-using-steam-and-press-with-in-vivo-high-resolution-spectra-at-9-4-t
#16
K-H Song, S-I Lim, C-H Yoo, B-Y Choe
PURPOSE: The objective of this study is to compare lipid contents using localized point-resolved spectroscopy (PRESS) and stimulated echo acquisition mode (STEAM) sequences to assess lipid resonances in the liver, using in vivo high-resolution spectra at 9.4 T. METHODS: The examinations were performed on a Bruker 9.4T scanner using 4-channel animal coil for higher resolution. We used PRESS (repetition time [TR]/ TE = 3500/20 ms; number of signal averages [NSA] = 128; acquisition data points = 2048) and STEAM (TR/TM/TE = 3500/10/20 ms; NSA = 128; acquisition data points = 2048)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28027401/breast-milk-polyunsaturated-fatty-acids-associations-with-adolescent-allergic-disease-and-lung-function
#17
N T Waidyatillake, R Stoney, F Thien, C J Lodge, J A Simpson, K J Allen, M J Abramson, B Erbas, C Svanes, S C Dharmage, A J Lowe
BACKGROUND: It has been hypothesized that n-3 PUFA in breast milk may assist immune and lung development. There are very limited data on possible long-term effects on allergic disease and lung function. The aim was to investigate associations of n-3 and n-6 PUFA levels in colostrum and breast milk with allergic disease and lung function at ages 12 and 18 years. METHODS: Polyunsaturated fatty acids were measured in 194 colostrum samples and in 118 three-month expressed breast milk samples from mothers of children enrolled in the Melbourne Atopy Cohort (MACS) Study, a high-risk birth cohort study...
December 27, 2016: Allergy
https://www.readbyqxmd.com/read/27973561/cross-classification-of-human-urinary-lipidome-by-sex-age-and-body-mass-index
#18
Kazuo Okemoto, Keiko Maekawa, Yoko Tajima, Masahiro Tohkin, Yoshiro Saito
Technological advancements in past decades have led to the development of integrative analytical approaches to lipidomics, such as liquid chromatography-mass spectrometry (LC/MS), and information about biogenic lipids is rapidly accumulating. Although several cohort-based studies have been conducted on the composition of urinary lipidome, the data on urinary lipids cross-classified by sex, age, and body mass index (BMI) are insufficient to screen for various abnormalities. To promote the development of urinary lipid metabolome-based diagnostic assay, we analyzed 60 urine samples from healthy white adults (young (c...
2016: PloS One
https://www.readbyqxmd.com/read/27919272/enhanced-lipid-and-biomass-production-by-a-newly-isolated-and-identified-marine-microalga
#19
Mouna Dammak, Sandra Mareike Haase, Ramzi Miladi, Faten Ben Amor, Mohamed Barkallah, David Gosset, Chantal Pichon, Bernhard Huchzermeyer, Imen Fendri, Michel Denis, Slim Abdelkafi
BACKGROUND: The increasing demand for microalgae lipids as an alternative to fish has encouraged researchers to explore oleaginous microalgae for food uses. In this context, optimization of growth and lipid production by the marine oleaginous V2-strain-microalgae is of great interest as it contains large amounts of mono-unsaturated (MUFAs) and poly-unsaturated fatty acids (PUFAs). METHODS: In this study, the isolated V2 strain was identified based on 23S rRNA gene...
December 5, 2016: Lipids in Health and Disease
https://www.readbyqxmd.com/read/27905210/erythrocyte-fatty-acid-composition-does-not-influence-levels-of-free-bioavailable-and-total-25-hydroxy-vitamin-d
#20
Martin Carlsson, Ingela Nilsson, Lars Brudin, Siv-Ping Von, Pär Wanby
In vitro, mono- and polyunsaturated fatty acids (FAs) may decrease the binding affinity of vitamin D metabolites for vitamin D-binding protein, which in turn may influence their bioavailability. FAs incorporated as phospholipids in erythrocyte (ery-) cell membranes reflect dietary intake. The purpose of this study was to investigate ery-FA composition in relation to markers for vitamin D. In healthy females (age 22.6 ± 2.0 years) total 25(OH)D was measured by LC-MS/MS (n = 78), free 25(OH)D with ELISA (n = 64 of 78), and bioavailable 25(OH)D was calculated...
February 2017: Scandinavian Journal of Clinical and Laboratory Investigation
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