Ana M Pescador, José P Lavrador, Alba D Baamonde, Christos Soumpasis, Prajwal Ghimire, José D S Mosquera, Carlos Fiandeiro, Holly Jones, Smita Gosavi, Arjel Lejarde, Emily Lawson, Sian Murace, Richard Gullan, Keyoumars Ashkan, Ranjeev Bhangoo, Francesco Vergani
Developing neurophysiological tools to predict WHO tumor grade can empower the treating teams for a better surgical decision-making process. A total of 38 patients with supratentorial diffuse gliomas underwent an asleep-awake-sedated craniotomies for tumor removal with intraoperative neuromonitoring. The resting motor threshold was calculated for different train stimulation paradigms during awake and asleep phases. Receiver operating characteristic analysis and Bayesian regression models were performed to analyze the prediction of tumor grading based on the resting motor threshold differences...
December 18, 2023: Cerebral Cortex