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https://www.readbyqxmd.com/read/27870056/cure-of-cancer-for-7-cancer-sites-in-the-flemish-region
#1
Geert Silversmit, David Jegou, Evelien Vaes, Elke Van Hoof, Els Goetghebeur, Liesbet Van Eycken
Cumulative relative survival curves for many cancers reach a plateau several years after diagnosis, indicating that the cancer survivor group has reached "statistical" cure. Parametric mixture cure model analysis on grouped relative survival curves provide an interesting way to determine the proportion of statistically cured cases and the mean survival time of the fatal cases in particular for population-based cancer registries. Based on the relative survival data from the Belgian Cancer Registry, parametric cure models were applied to seven cancer sites (cervix, colon, corpus uteri, skin melanoma, pancreas, stomach and oesophagus), at the Flemish Regional level for the incidence period 1999 to 2011...
November 21, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27848016/laparoscopic-supracervical-hysterectomy-for-the-larger-uterus-500%C3%A2-g-a-case-series-and-literature-review
#2
Lauren McGurk, Reeba Oliver, Funlayo Odejinmi
BACKGROUND: In clinical practice, the current trend for surgical hysterectomy for the large uterus is by laparotomy, where vaginal hysterectomy is not feasible. The benefits of a laparoscopic approach to hysterectomy are well documented, but limited literature is available on laparoscopic hysterectomy in the larger uterus. A supracervical hysterectomy should be considered for women, where there is no contraindication to a residual cervix. OBJECTIVE: To compare surgical outcomes for laparoscopic supracervical hysterectomy (LSH) in the large uterus (equal or greater than 500 g) compared with normal (<500 g), results were compared to the limited literature on this topic...
November 15, 2016: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/27813082/cancer-risks-in-nairobi-2000-2014-by-ethnic-group
#3
Anne Korir, Emma Yu Wang, Peter Sasieni, Nathan Okerosi, Victor Ronoh, D Maxwell Parkin
We investigated the ethnic differences in the risk of several cancers in the population of Nairobi, Kenya, using data from the Nairobi Cancer Registry. The registry records the variable "Tribe" for each case, a categorisation that includes, as well as 22 tribal groups, categories for Kenyans of European and of Asian origin, and non-Kenyan Africans. Tribes included in the final analysis were Kikuyu, Kamba, Kisii, Kalenjin, Luo, Luhya, Somalis, Asians, non-Kenyans, Caucasians, Other tribes and unknown. The largest group was taken as the reference category for the calculation of odds ratios; this was African Kenyans (for comparisons by race), and Kikuyus (the tribe with the largest numbers of cancer registrations (38% of the total)) for comparisons between the Kenyan tribes...
November 3, 2016: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/27775761/state-level-cancer-mortality-attributable-to-cigarette-smoking-in-the-united-states
#4
Joannie Lortet-Tieulent, Ann Goding Sauer, Rebecca L Siegel, Kimberly D Miller, Farhad Islami, Stacey A Fedewa, Eric J Jacobs, Ahmedin Jemal
Importance: State-specific information about the health burden of smoking is valuable because state-level initiatives are at the forefront of tobacco control. Smoking-attributable cancer mortality estimates are currently available nationally and by cancer, but not by state. Objective: To calculate the proportion of cancer deaths among adults 35 years and older that were attributable to cigarette smoking in 2014 in each state and the District of Columbia. Design, Setting, and Participants: The population-attributable fraction (PAF) of cancer deaths due to cigarette smoking was computed using relative risks for 12 smoking-related cancers (acute myeloid leukemia and cancers of the oral cavity and pharynx; esophagus; stomach; colorectum; liver; pancreas; larynx; trachea, lung, and bronchus; cervix uteri; kidney and renal pelvis; and urinary bladder) from large US prospective studies and state-specific smoking prevalence data from the Behavioral Risk Factor Surveillance System...
December 1, 2016: JAMA Internal Medicine
https://www.readbyqxmd.com/read/27774345/age-specific-incidence-of-five-major-cancers-in-nepal-2012
#5
Krishna Kanta Poudel, Zhibi Huang, Prakash Raj Neupane
BACKGROUND: Population based cancer registry is inevitable to measure the indicators of cancer. This retrospective study was conducted to perform the age specific incidence and age standardized rate of cancer by sex, age and sites in Nepal, 2012. MATERIALS AND METHODS: The data collected by hospital based National cancer registry programme of Nepal were used to calculate the age specific incidence of five major cancers by sex and sites. The age standardized rate of ten major cancers, both in males and females of 2012 was also performed...
June 2016: Nepal journal of epidemiology
https://www.readbyqxmd.com/read/27672265/human-papillomavirus-and-gastrointestinal-cancer-a-review
#6
REVIEW
Dania Bucchi, Fabrizio Stracci, Nicola Buonora, Giuseppe Masanotti
Human papillomavirus (HPV) is one of the most common sexually transmitted infections worldwide. Exposure to HPV is very common, and an estimated 65%-100% of sexually active adults are exposed to HPV in their lifetime. The majority of HPV infections are asymptomatic, but there is a 10% chance that individuals will develop a persistent infection and have an increased risk of developing a carcinoma. The International Agency for Research on Cancer has found that the following cancer sites have a strong causal relationship with HPV: cervix uteri, penis, vulva, vagina, anus and oropharynx, including the base of the tongue and the tonsils...
September 7, 2016: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/27629127/power-morcellation-for-women-undergoing-laparoscopic-supracervical-hysterectomy-safety-of-procedure-and-clinical-experience-from-426-cases
#7
Tomasz Rechberger, Paweł Miotła, Konrad Futyma, Alicja Ziętek, Aleksandra Filipczak, Ewa Rechberger, Justyna Szumiło, Aneta Adamiak-Godlewska
OBJECTIVES: Minimally invasive gynaecological surgeries are performed for several malignant and nonmalignant indications. The aim of our study was to evaluate the rate of unexpected malignancies among women who underwent laparoscopical supracervical hysterectomy (LASH) with power morcellation. MATERIAL AND METHODS: The retrospective analysis included clinical data of 426 consecutive female patients who underwent LASH with power morcellation due to presumed benign disorders (78...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27522713/-melanoma-and-human-papillomaviruses-is-there-an-outlook-for-study
#8
REVIEW
G M Volgareva, I N Mikhaylova, D A Golovina
Melanoma is one of the most aggressive human malignant tumors. Its incidence and mortality are growing steadily. Ultraviolet irradiation is the main risk factor for melanoma involved in melanomagenesis. The probability of viral etiology of melanoma has been discussed. Human papillomaviruses (HPV) have been mentioned among candidates for its etiologic agents because some HPV types are the powerful carcinogens causing cervical cancer and other cancers. The review analyses the literature data on the association of melanoma with HPV Several groupsfound HPVin skin melanomas as well as in mucosa; viruses of high oncogenic risk were detected in some cases...
2016: Vestnik Rossiĭskoĭ Akademii Meditsinskikh Nauk
https://www.readbyqxmd.com/read/27487537/specific-features-of-cytological-and-colposcopical-pattern-in-pregnant-women-with-benign-cervix-uteri-pathology-in-anamnesis
#9
Nataliya Yu Bysaha
INTRODUCTION: a tendency of increasing incidence of the cervix uteri precancer and cancer in women of reproductive age is noticed recently being related to the growth of number of the sexually-transmitted infections. The cervix uteri pathology incidence in women of fertile age is 20-25%. AIM: to study the specific features of the cytological and colposcopical pattern in pregnant patients with benign cervix uteri pathology in the anamnesis and the character of its change post partum...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27440742/interleukin-il-1-in-rat-parturition-il-1-receptors-1-and-2-and-accessory-proteins-abundance-in-pregnant-rat-uterus-at-term-regulation-by-progesterone
#10
Tomohito Ishiguro, Jun Takeda, Xin Fang, Heather Bronson, David M Olson
The role of interleukin-1 (IL-1), a pro-inflammatory cytokine, in parturition is typically noted by changes in its concentrations. Studying the expression of its receptor family, IL-1 receptor (IL-1R) 1, IL-1R2, IL-1R accessory protein (IL-1RAcP), and its predominantly brain isoform, IL-1RAcPb, during late gestation in the uterus in the Long-Evans rat is another. We assessed changes in their mRNA and protein relative abundance in the uterus and compared IL-1RAcP and IL-1RAcPb mRNA abundance in uterus, cervix, ovaries, placenta, and whole blood of Long-Evans rats during late gestation or in RU486 and progesterone-treated dams using quantitative real-time PCR and western immunoblotting...
July 2016: Physiological Reports
https://www.readbyqxmd.com/read/27436248/-the-accuracy-of-the-causes-of-death-and-the-estimated-trend-the-case-of-cervix-uteri
#11
Pamela Mancuso, Claudio Sacchettini, Massimo Vicentini, Stefania Caroli, Paolo Giorgi Rossi
BACKGROUND: reduction in cervical cancer mortality is the ultimate goal of the screening. Quality of death certificate reports has been improved over time, but they are still inaccurate, making it difficult to assess time trends in mortality. OBJECTIVES: to evaluate the accuracy of the topographic coding of causes of death and to estimate the mortality time trend for cervical cancer through the method of incidence-based mortality (IBM) using cancer registry (CR) data...
March 2016: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/27427380/clinical-validation-and-benchmarking-of-knowledge-based-imrt-and-vmat-treatment-planning-in-pelvic-anatomy
#12
Mohammad Hussein, Christopher P South, Miriam A Barry, Elizabeth J Adams, Tom J Jordan, Alexandra J Stewart, Andrew Nisbet
PURPOSE: The aim of this work was to determine whether a commercial knowledge-based treatment planning (KBP) module can efficiently produce IMRT and VMAT plans in the pelvic region (prostate & cervical cancer), and to assess sensitivity of plan quality to training data and model parameters. METHODS: Initial benchmarking of KBP was performed using prostate cancer cases. Structures and dose distributions from 40 patients previously treated using a 5-field IMRT technique were used for model training...
July 14, 2016: Radiotherapy and Oncology: Journal of the European Society for Therapeutic Radiology and Oncology
https://www.readbyqxmd.com/read/27407066/pap-tests-with-non-hyperchromatic-dyskariosis-are-often-associated-with-squamous-intraepithelial-lesions-of-the-cervix-uteri-with-eosinophilic-features
#13
Giulia Bellisano, Andrea Ambrosini-Spaltro, Gavino Faa, Alberto Ravarino, Andrea Piccin, Irmgard Peer, Armin Kasal, Fabio Vittadello, Giovanni Negri
BACKGROUND: Squamous intraepithelial lesions of the cervix uteri with eosinophilic features (eosinophilic dysplasia, ED) are a peculiar type of dysplasia with metaplastic phenotype which was described in histological specimens. The cytological features of these lesions have not been studied yet. METHODS: Histological samples from 66 women with features of ED and positive p16(INK4a) staining were included in the study. Within the previous year, all women had at least one pap-test, whose features were recorded and compared with 31 control samples with high-grade dysplasia of usual type...
October 2016: Diagnostic Cytopathology
https://www.readbyqxmd.com/read/27241146/-application-of-van-clear-and-xylene-in-the-detection-of-cervical-hterc-gene-by-fluorescence-in-situ-hybridization
#14
Zhiqiang Chen, Ying Wang, Xianjun Mi, Ang Chen, Shoujun Zhong, Huayong Huang, Xiumei Xu
OBJECTIVE: To observe the effect of Van-Clear on vamplification of human telomerase RNA component (hTERC) gene in cervical tissues by fluorescence in situ hybridization, and to determine the potential for Van-Clear to replace xylene.
 METHODS: A total of 278 specimens of cervix uteri were collected from inpatients of Department of Gynaecology in Boai Hospital of Zhongshan from January to February, 2015, with 81 cases of normal specimens, 68 cases of cervical intraepithelial neoplasia (CIN) I, 57cases of CIN2, 42 cases of CIN3 and 30 cases of cervical invasive cancer...
April 2016: Zhong Nan da Xue Xue Bao. Yi Xue Ban, Journal of Central South University. Medical Sciences
https://www.readbyqxmd.com/read/27221914/trend-of-cancer-incidence-in-nepal-from-2003-to-2012
#15
Krishna Kanta Poudel, Zhibi Huang, Prakash Raj Neupane
Trends in cancer incidence is a key tool to identify the pattern of cancer of any country. This retrospective study was performed to present the trends of change in cancer incidence in Nepal.The total number of cancer cases in males was 26,064 while the total number of females cancer cases was 29,867 throughout the 10 years from 2003 to 2012. The cancer incidence per 100,000 in males was 12.8 in 2003 and 25.8 people in 2012. Similarly, in females, the crude incidence rate was 15.1 in 2003 and 26.7 per 100,000 in 2012...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27216960/-pap-smear-for-mass-screening-results-of-an-african-experiment
#16
O-R Somé, N Zongo, S Ka, R Wardini, A Dem
OBJECTIVES: To assess the impact of smear test in the fight against cervix uteri cancer in Senegal. METHODS: This was a descriptive cross-sectional study of 1836 Pap smears performed in patients over 15 years during several screening campaigns in Senegal conducted between June 2010 and June 2012. We analyzed epidemiological data, pathological smears, and the proposed management. RESULTS: In 69% of cases, the women were less than 45 years old...
May 20, 2016: Gynécologie, Obstétrique & Fertilité
https://www.readbyqxmd.com/read/27195898/violence-against-women-and-cervical-cancer-screening-a-systematic-review
#17
Franciéle Marabotti Costa Leite, Maria Helena Costa Amorim, Cândida Caniçali Primo, Denise Petrucci Gigante
AIMS AND OBJECTIVES: To present a systematic review of papers published on the relationship between violence against women and cervical cancer screening. BACKGROUND: Violence against women is a serious public health problem. This phenomenon can have negative effects on victims' health and affect the frequency at which they receive cervical cancer screening. DESIGN: A systematic literature review. METHODS: This study was carried out in October 2015 with searches of the Lilacs, PubMed and Web of Science databases using the following keywords: violence, domestic violence, battered women, spouse abuse, Papanicolaou test, vaginal smears, early detection of cancer and cervix uteri...
May 16, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27172290/generation-of-rat-monoclonal-antibodies-against-human-pancreatic-ductal-adenocarcinoma-cells
#18
Kiyoshi Higashi, Nobuaki Fujii, Masahiko Kushida, Keita Yamada, Noriyuki Suzuki, Koichi Saito, Taro Tachibana
Pancreatic ductal adenocarcinoma is an aggressive tumor with a poor prognosis. Biomarkers that can detect the tumor in its early stages when it may be amenable to curative resection might improve prognosis. To discover novel markers expressed in primary pancreatic cancer, we generated a panel of monoclonal antibodies against pancreatic ductal adenocarcinoma cell line BxPC3 using a rat medial iliac lymph node method. The antigen recognized by 1B5A5 was expressed on the cell surface and secreted into the conditioned medium of BxPC3 cells, and characterized as glycoproteins with molecular mass between 60 and 90 kDa...
June 2016: Monoclonal Antibodies in Immunodiagnosis and Immunotherapy
https://www.readbyqxmd.com/read/27102013/cancer-incidence-in-urban-shanghai-1973-2010-an-updated-trend-and-age-period-cohort-effects
#19
Ping-Ping Bao, Ying Zheng, Chun-Xiao Wu, Zhe-Zhou Huang, Yu-Tang Gao, Fan Jin, Yong-Bing Xiang, Wei-Jian Zhong, Wei Lu, Fan Wu
BACKGROUND: To provide a comprehensive overview of temporal trends in cancer incidence during 1973-2010 in urban Shanghai. METHODS: The estimated annual percent changes (EAPCs) for the whole period and for the time segments in age-standardized incidence rates (ASR) were evaluated with Joinpoint analysis. Age-period-cohort (APC) models were modeled to examine the effects of age, period and birth cohort on cancer incidence. RESULTS: The overall ASR decreased slightly and significantly in males (EAPC of -0...
2016: BMC Cancer
https://www.readbyqxmd.com/read/27072219/can-pure-accelerated-radiotherapy-given-as-six-fractions-weekly-be-an-option-in-locally-advanced-carcinoma-cervix-results-of-a-prospective-randomized-phase-iii-trial
#20
Mukesh Sharma, Swaroop Revannasiddaiah, Manish Gupta, Rajeev K Seam, Manoj K Gupta, Madhup Rastogi
CONTEXT: Concurrent chemoradiation is presently the standard of care in locally advanced malignancy of the cervix uteri. But accelerated radiotherapy regimes have not been investigated much. AIMS: We conducted a randomized trial to compare the results of pure accelerated radiotherapy given as six fractions weekly to standard chemoradiotherapy in locally advanced carcinoma cervix patients. SETTINGS AND DESIGN: This was a prospective, phase III trial in which 106 patients of locally advanced (stage II and III) carcinoma cervix were randomized into two arms...
January 2016: Journal of Cancer Research and Therapeutics
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