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Percentile preterm infant

Cathrine Vedel, Anna Oldenburg, Katharina Worda, Helle Larsen, Anni Holmskov, Kirsten Riis Andreasen, Niels Uldbjerg, Jan Ramb, Birgit Bødker, Lillian Skibsted, Lene Sperling, Stefan Hinterberger, Lone Krebs, Helle Zingenberg, Eva-Christine Weiss, Isolde Strobl, Lone Laursen, Jeanette Tranberg Christensen, Vibeke Ersbak, Inger Stornes, Elisabeth Krampl-Bettelheim, Ann Tabor, Line Rode
OBJECTIVE: To investigate the association between chorionicity-specific intertwin birthweight (BW) discordance and adverse outcomes including long-term follow-up at 6, 18, and 48-60 months after term via Ages and Stages Questionnaire (ASQ). MATERIAL AND METHODS: In this secondary analysis of a cohort study (Oldenburg et al,n=1688) and a randomized controlled trial (PREDICT study,n=1045) twin pairs were divided into three groups according to chorionicity-specific BW discordance; <75(th) -percentile, 75(th) -90(th) -percentile and >90(th) -percentile...
November 18, 2016: Acta Obstetricia et Gynecologica Scandinavica
Hui Yeung, Michelle Leff, Kyung E Rhee
BACKGROUND: Breastfeeding is associated with decreased risk of childhood obesity. However, there is a strong correlation between maternal weight status and childhood obesity, and it is unclear whether or not breastfeeding among overweight mothers could mitigate this risk. Our goal was to examine whether or not exclusive breastfeeding (compared to formula feeding) among overweight and obese mothers is associated with lower weight-for-length (W/L) percentile at 1 year. MATERIALS AND METHODS: Data from the Infant Feeding Practices II study were used...
November 11, 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
Ellen W Demerath, William Johnson, Bridget A Davern, Christina G Anderson, Jeffrey S Shenberger, Sonya Misra, Sara E Ramel
BACKGROUND: The American Academy of Pediatrics (AAP) has recommended that nutritional management of the preterm infant should aim to achieve body composition that replicates the in utero fetus, but intrauterine body composition reference charts for preterm infants are lacking. OBJECTIVE: Our objective was to create body composition reference curves for preterm infants that approximate the body composition of the in utero fetus from 30 to 36 wk of gestation. DESIGN: A total of 223 ethnically diverse infants born at 30 + 0 to 36 + 6 wk of gestation were enrolled...
November 2, 2016: American Journal of Clinical Nutrition
C Wang, W Zhu, Y Wei, R Su, H Feng, E Hadar, M Hod, H Yang
OBJECTIVE: To evaluate the association between early pregnancy lipid profiles and pregnancy outcomes. STUDY DESIGN: Retrospective 6 months analysis of 5218 singleton pregnant women. Each participant's demographic and medical data were collected by questionnaires and medical records. Total cholesterol (TC), triglycerides (TG), high-density lipid cholesterol (HDL-C) and low-density lipid cholesterol (LDL-C) levels were divided into quartiles, and the women were categorized as having low (<25th percentile), referent (25 to <75th percentile) or high (>75th percentile) TC, TG, HDL-C and LDL-C values...
October 27, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Jin Lee, Hyun-Kyung Park, Ja Hye Kim, Yun Young Choi, Hyun Ju Lee
BACKGROUND: To examine bone mineral density in extremely low birth weight infants at discharge and investigate whether serial measurements of serum alkaline phosphatase (ALP) and phosphate can predict bone mineralization. METHODS: The individuals were 70 preterm infants. Serum calcium, phosphate, and ALP were measured at weekly intervals during admission in extremely low birth weight infants (mean gestational age, 25.3±2.1 weeks; birth weight, 812.8±141.1 g)...
September 30, 2016: Pediatrics and Neonatology
Kathryn J Sharma, Tania F Esakoff, Alyson Guillet, Richard M Burwick, Aaron B Caughey
OBJECTIVE: To determine whether adverse outcomes were more common in late preterm pregnancies complicated by preeclampsia and growth restriction compared to those affected by preeclampsia alone. METHODS: This was a retrospective cohort study of 8,927 singleton pregnancies with preeclampsia. Pregnancies with small for gestational age (SGA) neonates (birthweight <10(th) percentile) were compared to those appropriate for gestational age (AGA) neonates. Maternal outcomes included cesarean delivery (CD) rate, CD for fetal heart rate (FHR) abnormalities, abruption, postpartum hemorrhage (PPH), maternal transfusion, acute renal failure, and peripartum cardiomyopathy...
October 19, 2016: Journal of Maternal-fetal & Neonatal Medicine
E B Carter, M G Tuuli, A O Odibo, G A Macones, A G Cahill
OBJECTIVE: To investigate the association between the number of prenatal visits (PNVs) and pregnancy outcomes in women with gestational diabetes (GDM) and Type 2 diabetes mellitus (DM). STUDY DESIGN: A 4-year prospective cohort study of women with GDM and DM and was conducted. Patients ⩾75th percentile for number of PNVs were compared with those ⩽25th percentile. The primary outcomes were large for gestational age (LGA) with birth weight >90% and neonatal intensive care unit (NICU) admission for >24 h...
October 13, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
Nelly Padilla, Peter Fransson, Antonio Donaire, Francesc Figueras, Angela Arranz, Magdalena Sanz-Cortés, Violeta Tenorio, Núria Bargallo, Carme Junqué, Hugo Lagercrantz, Ulrika Ådén, Eduard Gratacós
Fetal growth restriction (FGR) affects brain development in preterm infants, but little is known about its effects on resting-state functional connectivity. We compared 20 preterm infants, born at <34 weeks of gestation with abnormal antenatal Doppler measurements and birth weights <10th percentile, with 20 appropriate for gestational age preterm infants of similar gestational age and 20 term infants. They were scanned without sedation at 12 months of age and screened for autistic traits at 26 months...
September 6, 2016: Cerebral Cortex
Michael W Rankin, Elizabeth Yakes Jimenez, Marina Caraco, Marie Collinson, Lisa Lostetter, Tara L DuPont
OBJECTIVE: To evaluate the accuracy of pre- and postfeeding weights to estimate enteral feeding volumes in preterm infants. STUDY DESIGN: Single-center prospective cohort study of infants 28-36 weeks' corrected age receiving gavage feedings. For each test weight, 3 pre- and 3 postgavage feeding weights were obtained by study personnel, blinded to feeding volume, via a specific protocol. The correlation between test weight difference and actual volume ingested was assessed by the use of summary statistics, Spearman rho, and graphical analyses...
August 29, 2016: Journal of Pediatrics
Eun Jin Kwon, Hye Ah Lee, Young-Ah You, Hyesook Park, Su Jin Cho, Eun Hee Ha, Young Ju Kim
The association of preterm birth with obesity and metabolic syndrome later in life is well established. Although the biological mechanism for this association is poorly understood, epigenetic alterations of metabolic-related genes in early life may have important roles in metabolic dysfunction. Thus, we investigated the associations of DNA methylations of melanocortin 4 receptor (MC4R) and hepatocyte nuclear factor 4 alpha (HNF4α) with metabolic profiles in cord blood of term and preterm infants.We measured metabolic profiles in cord blood samples of 85 term and 85 preterm infants...
August 2016: Medicine (Baltimore)
Sabine Huenecke, Esther Fryns, Boris Wittekindt, Horst Buxmann, Christoph Königs, Andrea Quaiser, Doris Fischer, Melanie Bremm, Thomas Klingebiel, Ulrike Koehl, Rolf Schloesser, Konrad Bochennek
Preterm newborns show an increased susceptibility to infections, conceivably related to their immature immune system. To gain further knowledge about the immune development in early preterm infants, we aimed to establish references for lymphocyte subsets and compare the maturation process during hospitalization to healthy term-born children and adolescents. For this purpose peripheral blood samples (n=153) were collected from 40 preterm infants; gestational age (GA) 26 to 30 week between 2(nd) and 6(th) day of life and were monitored in intervals of every 2 or rather 4 weeks until the end of hospitalization...
August 22, 2016: Scandinavian Journal of Immunology
Eisha Christian, Thomas Imahiyerobo, Alexis Johns, Pedro Sanchez, Mark D Krieger, J Gordon McComb, Mark Urata
INTRODUCTION: Patients with nonsyndromic sagittal craniosynostosis (SC) were previously thought to have normal neurocognitive development; however, a pattern of mild delays has been described in these patients. We reviewed our patients with SC to identify potential perinatal risk factors that serve as indicators for subsequent developmental delay. METHODS: Nonsyndromic patients with SC (n = 66) completed preoperative Bayley Scales of Infant and Toddler Development (III) with a single examiner between August 2009 and April 2015...
August 2016: Neurosurgery
Serdar Umit Sarici, Omer Gunes, Esad Koklu, Muhittin A Serdar
OBJECTIVE: We aimed to develop a transcutaneous bilirubin (TcB) nomogram for assessment of the risk of significant hyperbilirubinemia and prolonged jaundice during the first month of life in term and late-preterm Turkish newborns. METHODS: On the basis of the daily (3rd, 7th, 15th and 30th days) TcB measurements, 3rd, 10th, 25th, 50th, 75th, 90th and 97th percentiles, and 5 percentile tracks were obtained. TcB measurements were made by a transcutaneous bilirubinometer (JaundiceDetector JH20-1C)...
July 7, 2016: Journal of Tropical Pediatrics
Sarah K Dotters-Katz, Whitney M Humphrey, Kayli L Senz, Vanessa R Lee, Brian L Shaffer, Aaron B Caughey
Objective This study aims to evaluate the perinatal and neonatal outcomes associated with prenatal diagnosis of 45,X, both with and without fetal cardiac anomalies. Study Design A retrospective cohort of singleton pregnancies in California, 2005 to 2008, using vital statistics and International Classification of Diseases, Ninth Revision data, identifying prenatally diagnosed 45,X. Outcomes included preterm delivery, preeclampsia, intrauterine fetal demise (IUFD), cesarean section, small for gestational age (SGA), neonatal death, and infant death...
October 2016: American Journal of Perinatology
Jun Sasahara, Keisuke Ishii, Nagayoshi Umehara, Mari Oba, Kenji Kiyoshi, Takeshi Murakoshi, Tomohiro Tanemoto, Hiroshi Ishikawa, Kiyotake Ichizuka, Aya Yoshida, Kei Tanaka, Katsusuke Ozawa, Haruhiko Sago
AIM: The aim of this study was to evaluate the association between oligohydramnios and other perinatal factors in preterm small-for-gestational-age (SGA) infants who had cerebral palsy at 18 months of age or who had died before this age. METHODS: This retrospective study included 320 infants with birthweights < 3rd percentile delivered between 22 and 33 complete weeks of gestation. We evaluated the incidence of CP at 18 months of age and of death before this age...
June 29, 2016: Journal of Obstetrics and Gynaecology Research
Cristina T Navarrete, Lisa A Wrage, Waldemar A Carlo, Michele C Walsh, Wade Rich, Marie G Gantz, Abhik Das, Kurt Schibler, Nancy S Newman, Anthony J Piazza, Brenda B Poindexter, Seetha Shankaran, Pablo J Sánchez, Brenda H Morris, Ivan D Frantz, Krisa P Van Meurs, C Michael Cotten, Richard A Ehrenkranz, Edward F Bell, Kristi L Watterberg, Rosemary D Higgins, Shahnaz Duara
OBJECTIVE: To test whether infants randomized to a lower oxygen saturation (peripheral capillary oxygen saturation [SpO2]) target range while on supplemental oxygen from birth will have better growth velocity from birth to 36 weeks postmenstrual age (PMA) and less growth failure at 36 weeks PMA and 18-22 months corrected age. STUDY DESIGN: We evaluated a subgroup of 810 preterm infants from the Surfactant, Positive Pressure, and Oxygenation Randomized Trial, randomized at birth to lower (85%-89%, n = 402, PMA 26 ± 1 weeks, birth weight 839 ± 186 g) or higher (91%-95%, n = 408, PMA 26 ± 1 weeks, birth weight 840 ± 191 g) SpO2 target ranges...
September 2016: Journal of Pediatrics
Jamie L Morgan, David B Nelson, Scott W Roberts, C Edward Wells, Donald D McIntire, F Gary Cunningham
Objective To examine blood pressure patterns across pregnancy in women with treated chronic hypertension according to the occurrence of severe preeclampsia, growth restriction, and preterm birth <34 weeks. Methods This retrospective descriptive case study included only pregnant women receiving antihypertensive therapy. Using a random effects model, mean arterial pressures were plotted across gestation for women with and without preeclampsia, fetal growth restriction, and preterm birth <34 weeks with differences analyzed for each curve...
October 2016: American Journal of Perinatology
Mabel Berrueta, Jennifer Hemingway-Foday, Vanessa R Thorsten, Robert L Goldenberg, Waldemar A Carlo, Ana Garces, Archana Patel, Sarah Saleem, Omrana Pasha, Elwyn Chomba, Patricia L Hibberd, Nancy F Krebs, Shivaprasad Goudar, Richard J Derman, Fabian Esamai, Edward A Liechty, Janet L Moore, Elizabeth M McClure, Marion Koso-Thomas, Pierre M Buekens, José M Belizán, Fernando Althabe
BACKGROUND: Antenatal corticosteroids (ACS) for women at high risk of preterm birth is an effective intervention to reduce neonatal mortality among preterm babies delivered in hospital settings, but has not been widely used in low-middle resource settings. We sought to assess the rates of ACS use at all levels of health care in low and middle income countries (LMIC). METHODS: We assessed rates of ACS in 7 sites in 6 LMIC participating in the Eunice Kennedy Shriver National Institute of Child Health and Human Development's Global Network for Women and Children's Health Research Antenatal Corticosteroids Trial (ACT), a cluster-randomized trial to assess the feasibility, effectiveness, and safety of a multifaceted intervention designed to increase the use of ACS...
2016: Reproductive Health
Ju Lee Oei, Alpana Ghadge, Elisabeth Coates, Ian M Wright, Ola D Saugstad, Maximo Vento, Giuseppe Buonocore, Tatsuo Nagashima, Keiji Suzuki, Shiguhero Hosono, Peter G Davis, Paul Craven, Lisa Askie, Jennifer Dawson, Shalabh Garg, Anthony Keech, Yacov Rabi, John Smyth, Sunil Sinha, Ben Stenson, Kei Lui, Carol Lu Hunter, William Tarnow Mordi
AIM: This study determined current international clinical practice and opinions regarding initial fractional inspired oxygen (FiO2 ) and pulse oximetry (SpO2 ) targets for delivery room resuscitation of preterm infants of less than 29 weeks of gestation. METHODS: An online survey was disseminated to neonatal clinicians via established professional clinical networks using a web-based survey programme between March 9 and June 30, 2015. RESULTS: Of the 630 responses from 25 countries, 60% were from neonatologists...
September 2016: Acta Paediatrica
Steven Caskey, Aisling Gough, Stephen Rowan, Scott Gillespie, Jim Clarke, Marshall Riley, Jacqui Megarry, Paul Nicholls, Chris Patterson, Henry L Halliday, Michael D Shields, Lorcan McGarvey
RATIONALE: As more preterm infants recover from severe bronchopulmonary dysplasia (BPD), it is critical to understand the clinical consequences of this condition on the lung health of adult survivors. OBJECTIVES: To assess structural and functional lung parameters in young adult BPD survivors and preterm and term control subjects. METHODS: Young adult survivors of BPD (mean age, 24 yr) underwent spirometry, lung volume assessment, transfer factor, lung clearance index, and fractional exhaled nitric oxide measurements, together with high-resolution chest computed tomography and cardiopulmonary exercise testing...
August 2016: Annals of the American Thoracic Society
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