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https://www.readbyqxmd.com/read/29561173/evaluation-of-statin-eligibility-prescribing-practices-and-therapeutic-responses-using-atp-iii-acc-aha-and-nla-dyslipidemia-treatment-guidelines-in-a-large-urban-cohort-of-hiv-infected-outpatients
#1
Matthew E Levy, Alan E Greenberg, Manya Magnus, Naji Younes, Amanda Castel
Statin coverage has been examined among HIV-infected patients using Adult Treatment Panel III (ATP III) and American College of Cardiology/American Heart Association (ACC/AHA) guidelines, although not with newer National Lipid Association (NLA) guidelines. We investigated statin eligibility, prescribing practices, and therapeutic responses using these three guidelines. Sociodemographic, clinical, and laboratory data were collected between 2011 and 2016 for HIV-infected outpatients enrolled in the DC Cohort, a multi-center, prospective, observational study in Washington, DC...
February 2018: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/29548302/comparing-dedicated-and-designated-models-of-integrating-mental-health-into-chronic-disease-care-study-protocol-for-a-cluster-randomized-controlled-trial
#2
Bronwyn Myers, Crick Lund, Carl Lombard, John Joska, Naomi Levitt, Christopher Butler, Susan Cleary, Tracey Naledi, Peter Milligan, Dan J Stein, Katherine Sorsdahl
BACKGROUND: In low- and middle-income countries (LMIC), it is uncertain whether a "dedicated" approach to integrating mental health care (wherein a community health worker (CHW) has the sole responsibility of delivering mental health care) or a "designated" approach (wherein a CHW provides this service in addition to usual responsibilities) is most effective and cost-effective. This study aims to compare the effectiveness and cost-effectiveness of these two models of service integration relative to treatment as usual (TAU) for improving mental health and chronic disease outcomes among patients with HIV or diabetes...
March 16, 2018: Trials
https://www.readbyqxmd.com/read/29435953/role-of-noncommunicable-diseases-ncds-in-resource-limited-settings-rls
#3
REVIEW
Mosepele Mosepele, Elizabeth Botsile
PURPOSE OF REVIEW: As access to effective antiretroviral therapy (ART) expands globally, a decline in AIDS-related morbidity and mortality has been complicated by rising rates of noncommunicable diseases (NCDs). This review provides a brief description of NCDs and existing gaps on knowledge about NCDs among HIV-infected adults mostly in Africa. RECENT FINDINGS: Recent reports show that one in every five persons living with HIV has a chronic illness, predominantly diabetes and/or hypertension, depression, and most of these conditions are either not diagnosed or not being managed...
February 12, 2018: Current HIV/AIDS Reports
https://www.readbyqxmd.com/read/29430957/anxiety-depression-and-health-related-quality-of-life-in-aging-people-living-with-hiv-compared-to-diabetes-patients-and-patients-with-minor-health-conditions-a-longitudinal-study
#4
Joram Ronel, Andreas Dinkel, Eva Wolf, Birgitt Marten-Mittag, Birgit Mueck, Christoph Mayr, Christian Hoffmann, Martin Karwat, Knud Schewe, Axel Baumgarten, Hans Jaeger
HIV infection has evolved from a fatal to a treatable condition, leading to an increase in the rate of elderly People Living with HIV (PLWH). However, little is known about the psychosocial burden of elderly PLWH. Thus, the aim of this longitudinal multi-center cohort study was to investigate whether elderly PLWH experience more anxiety and depression and reduced health related quality of life (HRQOL) compared to elderly patients with other chronic conditions. PLWH were compared to diabetes patients (DM) and patients with minor health conditions (MHC), e...
February 11, 2018: Psychology, Health & Medicine
https://www.readbyqxmd.com/read/29424096/low-education-and-lack-of-spousal-relationship-are-associated-with-dementia-in-older-adults-with-diabetes-mellitus-in-nigeria
#5
Abdulkareem J Yusuf, Olusegun Baiyewu, Adamu G Bakari, Sani B Garko, Mohammed E-B Jibril, Aishatu M Suleiman, Haruna M Muktar, Micheal A Amedu
BACKGROUND: The relationship between dementia and type 2 diabetes mellitus (T2DM) in older adults is well established in the literature. However, there have been few studies on this relationship in older adults living in low- and middle-income countries, and most demographic projections predict that older adult population will increase substantially in these regions by 2050. METHODS: In this study, older adults with T2DM attending a tertiary health facility were examined and compared with community-dwelling older adults without T2DM...
February 8, 2018: Psychogeriatrics: the Official Journal of the Japanese Psychogeriatric Society
https://www.readbyqxmd.com/read/29383534/psychosocial-complications-of-hiv-aids-metabolic-disorder-comorbidities-among-patients-in-a-rural-area-of-southeastern-united-states
#6
Dominica Hernandez, Seth C Kalichman, Harold P Katner, Kaylee Burnham, Moira O Kalichman, Marnie Hill
As people living with HIV experience longer life-expectancies resulting from antiretroviral therapy, comorbid conditions are increasing, particularly metabolic disorders. There is potential for psychosocial factors such as stigma experiences, depression, and alcohol use to complicate both HIV infection and metabolic disorders, including diabetes mellitus and hyperlipidemia. While the impact of these psychosocial factors on HIV infection alone are widely studied, their role in potentially complicating HIV co-morbid metabolic conditions has received little attention...
January 30, 2018: Journal of Behavioral Medicine
https://www.readbyqxmd.com/read/29369158/the-growing-burden-of-non-communicable-disease-among-persons-living-with-hiv-in-zimbabwe
#7
Mikaela Smit, Jack Olney, Nathan P Ford, Marco Vitoria, Simon Gregson, Anna Vassall, Timothy B Hallett
OBJECTIVES: We aim to characterise the future noncommunicable disease (NCD) burden in Zimbabwe to identify future health system priorities. METHODS: We developed an individual-based multidisease model for Zimbabwe, simulating births, deaths, infection with HIV and progression, and key NCD (asthma, chronic kidney disease (CKD), depression, diabetes, hypertension, stroke, breast, cervical, colorectal, liver, oesophageal, prostate and all other cancers). The model was parameterised using national and regional surveillance and epidemiological data...
January 23, 2018: AIDS
https://www.readbyqxmd.com/read/29323557/neuropsychological-assessment-of-412-hiv-infected-individuals-in-s%C3%A3-o-paulo-brazil
#8
Maria Rita Polo Gascón, José Ernesto Vidal, Yolanda Marques Mazzaro, Jerusa Smid, Rosa Maria Nascimento Marcusso, Claudio Garcia Capitão, Elizeu Macedo Coutinho, Glaucia Rosana Guerra Benute, Mara Cristina Souza De Lucia, Augusto César Penalva de Oliveira
HIV-associated neurocognitive disorders (HAND) remain frequent even among individuals receiving combined antiretroviral therapy (cART). In addition, HAND may adversely affect the quality of life and adherence to cART. There is scarce epidemiological information about HAND in Latin America. This cross-sectional study recruited HIV-infected patients from a tertiary teaching institution in São Paulo, Brazil, between May 2013 and February 2015. The patients were adults with at least 4 years of education and patients with current neurological or psychiatric diseases were excluded...
January 2018: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/29228820/associations-between-depressive-symptomatology-and-neurocognitive-impairment-in-hiv-aids
#9
Sarah Tymchuk, Daniela Gomez, Noshin Koenig, M John Gill, Esther Fujiwara, Christopher Power
OBJECTIVE: Mood disorders and neurocognitive impairments are debilitating conditions among patients with HIV/AIDS. How these comorbidities interact and their relationships to systemic factors remain uncertain. Herein, we investigated factors contributing to depressive symptomatology (DS) in a prospective cohort of patients with HIV/AIDS in active care that included neuropsychological assessment. METHODS: Among patients with HIV/AIDS receiving combination antiretroviral therapy (cART) and ongoing clinical assessments including measures of sleep, health-related quality of life (HQoL), neuropsychological testing, and mood evaluation (Patient Health Questionnaire-9 [PHQ-9]) were performed...
January 1, 2017: Canadian Journal of Psychiatry. Revue Canadienne de Psychiatrie
https://www.readbyqxmd.com/read/29197403/setting-priorities-for-knowledge-translation-of-cochrane-reviews-for-health-equity-evidence-for-equity
#10
Peter Tugwell, Jennifer Petkovic, Vivian Welch, Jennifer Vincent, Zulfiqar A Bhutta, Rachel Churchill, Don deSavigny, Lawrence Mbuagbaw, Tomas Pantoja
BACKGROUND: A focus on equity in health can be seen in many global development goals and reports, research and international declarations. With the development of a relevant framework and methods, the Campbell and Cochrane Equity Methods Group has encouraged the application of an 'equity lens' to systematic reviews, and many organizations publish reviews intended to address health equity. The purpose of the Evidence for Equity (E4E) project was to conduct a priority-setting exercise and apply an equity lens by developing a knowledge translation product comprising summaries of systematic reviews from the Cochrane Library...
December 2, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/29100941/impact-of-clinical-pharmacist-services-delivered-via-telemedicine-in-the-outpatient-or-ambulatory-care-setting-a-systematic-review
#11
REVIEW
Joshua D Niznik, Harvey He, Sandra L Kane-Gill
BACKGROUND: Utilization of telemedicine allows pharmacists to extend the reach of clinical interventions, connecting them with patients and providers, but the overall impact of these services is under-studied. OBJECTIVE: Identify the impact of clinical pharmacist telemedicine interventions on clinical outcomes, subsequently defined as clinical disease management, patient self-management, and adherence, in outpatient or ambulatory settings. METHODS: A literature search was conducted from database inception through May 2016 in Medline, SCOPUS, and EMBASE...
October 28, 2017: Research in Social & Administrative Pharmacy: RSAP
https://www.readbyqxmd.com/read/29023938/a-pharmacist-led-program-to-evaluate-and-reduce-polypharmacy-and-potentially-inappropriate-prescribing-in-older-hiv-positive-patients
#12
Ian R McNicholl, Monica Gandhi, C Bradley Hare, Meredith Greene, Edgar Pierluissi
OBJECTIVE: The goal of this pharmacist-led study was to utilize two validated instruments, Beers Criteria and Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP), to assess potentially inappropriate prescribing (PIP) in older patients infected with the human immunodeficiency virus (HIV) and evaluate pharmacist interventions. DESIGN: Prospective randomized interventional trial. SETTING: Large urban clinic providing interdisciplinary primary and HIV care for ~2700 HIV-positive publicly insured patients...
December 2017: Pharmacotherapy
https://www.readbyqxmd.com/read/28743495/association-between-physical-activity-depression-and-diabetes-in-urban-dwelling-people-living-with-hiv
#13
Norberto N Quiles, Joseph T Ciccolo, Carol Ewing Garber
Physical activity (PA) may improve physical and mental health in people living with HIV (PLWH). However, the associations between PA participation and physical and mental health problems of PLWH in urban settings remain largely unknown. Our objective was to determine the relationships between PA and physical and mental health in urban-dwelling PLWH. There were 289 adult PLWH who responded to an electronic survey including questions on PA and current physical and mental health. The associations between physical and mental health and PA were investigated using linear and logistic regression...
November 2017: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/28644158/radiology-case-of-the-month-idiopathic-cd4-lymphocytopenia
#14
Chris Malone, Neel D Gupta, Amit Kothari, Enrique Palacios, Harold Neitzschman
A 39 year-old male with a history of diabetes, retinitis pigmentosa, and genital warts presented with intractable occipital headaches accompanied with nausea and vomiting. The patient had markedly depressed CD4 counts. Furthermore the patient tested negative for HIV and HTLV 1/2 and had normal immunoglobulin levels. During hospital course the patient underwent a lumbar puncture and multiple imaging exams, including both CT and MR. Except for occasional nausea and vomiting controlled by therapeutic lumbar punctures, phenergan, and dilaudid the patient's hospital course was uncomplicated...
May 2017: Journal of the Louisiana State Medical Society: Official Organ of the Louisiana State Medical Society
https://www.readbyqxmd.com/read/28490237/phytochemistry-and-pharmacological-activities-of-the-genus-swertia-gentianaceae-a-review
#15
REVIEW
Jie Li, Yan-Li Zhao, Heng-Yu Huang, Yuan-Zhong Wang
Swertia plants have been considered to be medicinal plants useful for the treatment of various ailments for thousands of years, especially in Asian countries. This is due to the broad variety of chemical compounds that provide multiple ligands for bonding to different endogenous biomacromolecules for patients. Chemical constituents and pharmacological activities of Swertia plants are summarized in this paper. Approximately 419 metabolites and 40 bioactive compounds have been reported from 30 Swertia species, including xanthones, flavonoids, seco-iridiods, iridiods, triterpenoids, alkaloids, volatiles, and other secondary metabolites...
2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28470547/disparities-in-us-healthcare-provider-screening-and-advice-for-cessation-across-chronic-medical-conditions-and-tobacco-products
#16
Diana R Keith, Cassandra A Stanton, Diann E Gaalema, Janice Y Bunn, Nathan J Doogan, Ryan Redner, Allison N Kurti, Antonio Cepeda-Benito, Alexa A Lopez, Adam L Morehead, Megan E Roberts, Stephen T Higgins
BACKGROUND: Disparities in tobacco use are worsening in the United States, disproportionately affecting those with chronic medical conditions. One possible contributor is that physicians may not screen and advise cessation uniformly across patients and/or tobacco products. OBJECTIVE: This study examined provider communications regarding cigarette and non-cigarette tobacco products among adults with chronic conditions. DESIGN: Cross-sectional study drawn from two waves (2013-2014) of the National Survey on Drug Use and Health (NSDUH)...
September 2017: Journal of General Internal Medicine
https://www.readbyqxmd.com/read/28412229/characteristics-and-factors-associated-with-pain-in-older-homeless-individuals-results-from-the-health-outcomes-in-people-experiencing-homelessness-in-older-middle-age-hope-home-study
#17
John C Landefeld, Christine Miaskowski, Lina Tieu, Claudia Ponath, Christopher T Lee, David Guzman, Margot Kushel
Individuals experiencing homelessness in the United States are aging; little is known about chronic pain in this population. In a cross-sectional, population-based study, we interviewed 350 homeless individuals aged 50 years and older to describe pain experienced by older persons experiencing homelessness and to assess factors associated with chronic moderate to severe pain, defined as pain lasting ≥3 months, with a past week average severity score of 5 to 10 (scale 0-10). The median age of participants was 58 years...
September 2017: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28271846/non-communicable-disease-syndemics-poverty-depression-and-diabetes-among-low-income-populations
#18
REVIEW
Emily Mendenhall, Brandon A Kohrt, Shane A Norris, David Ndetei, Dorairaj Prabhakaran
The co-occurrence of health burdens in transitioning populations, particularly in specific socioeconomic and cultural contexts, calls for conceptual frameworks to improve understanding of risk factors, so as to better design and implement prevention and intervention programmes to address comorbidities. The concept of a syndemic, developed by medical anthropologists, provides such a framework for preventing and treating comorbidities. The term syndemic refers to synergistic health problems that affect the health of a population within the context of persistent social and economic inequalities...
March 4, 2017: Lancet
https://www.readbyqxmd.com/read/28097614/comprehensive-and-medically-appropriate-food-support-is-associated-with-improved-hiv-and-diabetes-health
#19
Kartika Palar, Tessa Napoles, Lee L Hufstedler, Hilary Seligman, Fredrick M Hecht, Kimberly Madsen, Mark Ryle, Simon Pitchford, Edward A Frongillo, Sheri D Weiser
Food insecurity is associated with negative chronic health outcomes, yet few studies have examined how providing medically appropriate food assistance to food-insecure individuals may improve health outcomes in resource-rich settings. We evaluated a community-based food support intervention in the San Francisco Bay Area for people living with HIV and/or type 2 diabetes mellitus (T2DM) to determine the feasibility, acceptability, and potential impact of the intervention on nutritional, mental health, disease management, healthcare utilization, and physical health outcomes...
February 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28002184/prevalence-and-predictors-of-hospitalizations-among-hiv-infected-and-at-risk-hiv-uninfected-women
#20
Anna L Hotton, Kathleen M Weber, Ronald C Hershow, Kathryn Anastos, Peter Bacchetti, Elizabeth T Golub, Deborah Gustafson, Alexandra M Levine, Mary Young, Mardge H Cohen
OBJECTIVES: We evaluated the Veterans Aging Cohort Study (VACS) Index score, an index composed of age, CD4 count, viral load, hemoglobin, Hepatitis C coinfection, Fibrosis Index-4, and estimated glomerular filtration rate, and psychosocial and clinical risk factors for all-cause hospitalization among HIV-infected women on highly active antiretroviral therapy and HIV-uninfected women. METHODS: Data were collected from 2008 to 2014 from 1585 highly active antiretroviral therapy-experienced HIV infected and 692 uninfected women...
June 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
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