keyword
MENU ▼
Read by QxMD icon Read
search

formic acid

keyword
https://www.readbyqxmd.com/read/28812322/reactivity-of-silanes-with-tbuponop-ruthenium-dichloride-facile-synthesis-of-chloro-silyl-ruthenium-compounds-and-subsequent-reactivity
#1
James Matthew Boncella, Nickolas H Anderson, Aaron M Tondreau
The coordination of tBuPONOP (tBuPONOP = 2,6-bis(ditertbutylphosphinito)pyridine) to different ruthenium starting materials, to generate (tBuPONOP)RuCl2, was investigated. The 16-electron species (tBuPONOP)Ru(H)Cl was produced from the reaction of triethylsilane with (tBuPONOP)RuCl2. Reactions of (tBuPONOP)RuCl2 with both phenylsilane or diphenylsilane afforded the 16-electron hydrido-silyl species (tBuPONOP)Ru(H)(PhSiCl2) and (tBuPONOP)Ru(H)(Ph2SiCl), respectively. Reactions of all three of these complexes with silver triflate afforded the simple salt metathesis products of (tBuPONOP)Ru(H)(OTf), (tBuPONOP)Ru(H)(PhSiCl(OTf)), and (tBuPONOP)Ru(H)(Ph2Si(OTf))...
August 15, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28811116/identification-of-nocardia-streptomyces-and-tsukamurella-using-maldi-tof-ms-with-the-bruker-biotyper
#2
Melanie L Yarbrough, William Lainhart, Carey-Ann D Burnham
Nocardia species are the most commonly isolated aerobic actinomycetes from human clinical specimens. Our objective was to assess the identification of clinically relevant actinomycetes using the Bruker Biotyper MALDI-TOF system, including comparison of extraction methods, Biotyper library versions, score cutoffs, and media. Banked Streptomyces (n=10), Tsukamurella (n=2), and Nocardia isolates (n=60) were cultured and extracted using three methods: mycobacterial extraction, ethanol formic acid extraction, or direct on-target extraction...
July 1, 2017: Diagnostic Microbiology and Infectious Disease
https://www.readbyqxmd.com/read/28811018/direct-coupling-of-electromembrane-extraction-to-mass-spectrometry-advancing-the-probe-functionality-toward-measurements-of-zwitterionic-drug-metabolites
#3
Torstein Kige Rye, David Fuchs, Stig Pedersen-Bjergaard, Nickolaj Jacob Petersen
A triple-flow electromembrane extraction (EME) probe was developed and coupled directly to electrospray-ionization mass spectrometry (ESI-MS). Metabolic reaction mixtures (pH 7.4) containing drug substances and related metabolites were continuously drawn (20 μL/min) into the EME probe in one flow channel, and mixed inside the probe with 7.5 μL min(-1) of 1 M formic acid as make-up flow from a second flow channel. Following this acidification, the drug substances and their related metabolites were continuously extracted by EME at 400 V, across a supported liquid membrane (SLM) comprising 2-nitrophenyl octyl ether (and for some experiments containing 30% triphenyl phosphate (TPP)), and into 20 μL min(-1) of formic acid as acceptor phase, which was introduced through a third flow channel...
August 29, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28810079/lc-esi-ms-ms-determination-of-4-methylpyrazole-in-dog-plasma-and-its-application-to-a-pharmacokinetic-study-in-dogs
#4
Devaraj V Chandrasekhar, Suresh P S, Sreekanth Dittakavi, Rakesh A Hiremath, Ravi Kanth Bhamidipati, Wolfgang Richter, Nuggehally R Srinivas, Ramesh Mullangi
A simple, specific, sensitive and rapid LC-ESI-MS/MS method has been developed and validated for the quantification of 4-methylpyrazole in dog plasma using N-methylnicotinamide-d4 as an internal standard (IS) as per regulatory guideline.s Sample preparation was accomplished through a simple protein precipitation. Chromatographic separation of 4-methylpyrazole and the IS was performed on a monolithic (Chromolith RP-18e) column using an isocratic mobile phase comprising 0.2% formic acid in water and acetonitrile (20:80, v/v) at a flow rate of 1...
August 15, 2017: Biomedical Chromatography: BMC
https://www.readbyqxmd.com/read/28808600/simultaneous-determination-of-11-compounds-in-gualou-guizhi-granule-and-pharmacokinetics-study-by-uplc-ms-ms
#5
Chengtao Sun, Wen Xu, Yuqin Zhang, Lishuang Yu, Miao Ye, Kedan Chu, Wei Xu, Yu Lin
A rapid and sensitive ultrafast performance liquid chromatography-tandem mass spectrometry method (UPLC-MS/MS) was developed for the simultaneous determination of 11 compounds in Gualou Guizhi Granule (GLGZG), including liquiritin, isoliquiritin, liquirtin apioside, isoliquiritin apioside, liquiritigenin, isoliquiritigenin, glycyrrhizic acid, glycyrrhetinic acid, paeoniflorin, albiflorin, and paeoniflorin sulfonate in rat plasma. UPLC-MS/MS assay with negative ion mode was performed on a Waters CORTECS C18 (2...
2017: Journal of Analytical Methods in Chemistry
https://www.readbyqxmd.com/read/28807091/rapid-and-sensitive-determination-of-13-components-in-a-traditional-chinese-medicine-formula-of-da-huang-gan-cao-decoction-by-high-performance-liquid-chromatography-coupled-with-triple-quadrupole-mass-spectrometry
#6
Jialin Qu, Nan Xiao, Hua Sui, Lina Liang, Jing Chen, Weiling Li, Dong Shang
Da-Huang-Gan-Cao decoction (DHGCD), which is a classic formula in traditional Chinese medicine, has been clinically used for the treatment of vomiting, constipation, pancreatitis, and cholelithiasis in China and Japan. In this study, a rapid and validated method using HPLC coupled with triple quadrupole MS was developed for the simultaneous determination of 13 components in DHGCD. Separation was performed on an XBridge BEH C18 column (50 × 2.1 mm, 2.5 μm) with a gradient elution of acetonitrile and 0.1% formic acid in water...
June 15, 2017: Journal of AOAC International
https://www.readbyqxmd.com/read/28806568/a-simple-high-performance-liquid-chromatography-mass-spectrometry-method-for-therapeutic-drug-monitoring-of-isavuconazole-and-four-other-antifungal-drugs-in-human-plasma-samples
#7
Giovanna Fatiguso, Fabio Favata, Ilaria Zedda, Amedeo De Nicolò, Jessica Cusato, Valeria Avataneo, Giovanni Di Perri, Antonio D'Avolio
Triazoles chanced the prevention and treatment of invasive fungal infections, but their pharmacokinetic properties are still unclear. In particular, isavuconazole (ISC) is a new broad-spectrum antifungal triazole approved in 2015 as first-line treatment for intravenous and oral use against invasive aspergillosis and for mucormycosis. Nowadays, the optimal management of the treatments with triazoles requires the use of Therapeutic Drug Monitoring (TDM), in order to prevent sub-therapeutic or toxic concentrations...
August 5, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28805226/the-reaction-of-criegee-intermediate-ch2oo-with-water-dimer-primary-products-and-atmospheric-impact
#8
Leonid Sheps, Brandon Rotavera, Arkke J Eskola, David L Osborn, Craig A Taatjes, Kendrew Au, Dudley E Shallcross, M Anwar H Khan, Carl J Percival
The rapid reaction of the smallest Criegee intermediate, CH2OO, with water dimers is the dominant removal mechanism for CH2OO in the Earth's atmosphere, but its products are not well understood. This reaction was recently suggested as a significant source of the most abundant tropospheric organic acid, formic acid (HCOOH), which is consistently underpredicted by atmospheric models. However, using time-resolved measurements of reaction kinetics by UV absorption and product analysis by photoionization mass spectrometry, we show that the primary products of this reaction are formaldehyde and hydroxymethyl hydroperoxide (HMHP), with direct HCOOH yields of less than 10%...
August 14, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28803105/glucose-bioconversion-profile-in-the-syngas-metabolizing-species-clostridium-carboxidivorans
#9
Ánxela Fernández-Naveira, María C Veiga, Christian Kennes
Some clostridia produce alcohols (ethanol, butanol, hexanol) from gases (CO, CO2, H2) and others from carbohydrates (e.g., glucose). C. carboxidivorans can metabolize both gases as well as glucose. However, its bioconversion profile on glucose had not been reported. It was observed that C. carboxidivorans does not follow a typical solventogenic stage when grown on glucose. Indeed, at pH 6.2, it produced first a broad range of acids (acetic, butyric, hexanoic, formic, and lactic acids), several of which are generally not found, under similar conditions, during gas fermentation...
August 2, 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28802242/an-lc-ms-ms-method-for-simultaneous-determination-of-nine-steroidal-saponins-from-paris-polyphylla-var-in-rat-plasma-and-its-application-to-pharmacokinetic-study
#10
Guangyi Yang, Wei Lu, Meng Pan, Chenning Zhang, Yuan Zhou, Pei Hu, Ming Hu, Gao Song
Paris polyphylla var is an herbal plant herb widely used in Traditional Chinese Medicine. The purpose of this study is to develop an Ultra Performance Liquid Chromatography-tandem mass spectrometer (UPLC-MS) method to quantify the major components (i.e., nine saponins) from P. polyphylla in plasma samples. A UItra BiPh column (100×2.1mm, 5μm) was used with acetonitrile/0.1% formic acid in water as mobile phases. The analytes were quantified using a Waters XEVO TQ mass spectrometer via multiple reaction monitoring (MRM) with positive scan mode...
August 1, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28802217/comparatively-evaluating-the-pharmacokinetic-of-fifteen-constituents-in-normal-and-blood-deficiency-rats-after-oral-administration-of-xin-sheng-hua-granule-by-uplc-ms-ms
#11
Han-Qing Pang, Yu-Ping Tang, Yu-Jie Cao, Ya-Jie Tan, Yi Jin, Xu-Qin Shi, Sheng-Liang Huang, Da-Zheng Sun, Jin Sun, Zhi-Shu Tang, Jin-Ao Duan
Xin-Sheng-Hua Granule (XSHG), a famous traditional Chinese medicine prescription, are clinically applied for the treatment of postpartum disease through nourishing blood and promoting blood circulation. In this investigation, a multi-constituents (trigonelline, stachydrine hydrochloride, hydroxysafflor yellow A, chlorogenic acid, amygdalin, leonurine, liquiritin, ferulic acid, senkyunolide I, senkyunolide H, glycyrrhizic acid, senkyunolide A, ligustilide, butylidenephthalide and glycyrrhetinic acid) pharmacokinetic study of XSHG was conducted for the first time...
July 30, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28800549/simultaneous-determination-of-bentazone-and-its-metabolites-in-postmortem-whole-blood-using-liquid-chromatography-tandem-mass-spectrometry
#12
Byungsuk Cho, Suncheun Kim, Sangwhan In, Sanggil Choe
A liquid chromatography-tandem mass spectrometry method with solid-phase extraction (SPE) was developed and validated for the detection and quantitation of bentazone and its two hydroxylated metabolites, 6-hydroxybentazone and 8-hydroxybentazone, in postmortem blood. Sample cleanup was performed using a hydrophilic-lipophilic balanced (HLB) SPE cartridge and then separated on a C18 LC column using a gradient elution of 0.1% formic acid in distilled water and 0.1% formic acid in methanol. The identification of bentazone and its hydroxylated metabolites was performed using tandem mass spectrometry with electrospray ionization in negative ion mode with selective reaction monitoring...
July 29, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28795493/-molecularly-imprinted-chromatography-fails-to-distinguish-homeopatic-remedy-from-placebo
#13
Roman Kaliszan, Małgorzata Waszczuk-Jankowska, Danuta Siluk, Bartosz Wielgomas
It was sensation when Dr. J. Beneviste reported alleged experimental biological evidence of the water memory effect (E. Dayenas et al. Nature 333, 816-818, 1988; https://doi.org/10.1038/333816a0). These experiments have never been reproduced in controlled conditions, however. Instead, the hypothesis that water can be imprinted with the memory of past solutes was ruled out (J. Maddox et al. Nature 334, 287-290, 1988; https://doi.org/10.1038/334287a0). At present, so-called "molecular imprinting" is a technology of preparing polymer matrices as affinity-based analyte separation media (J...
August 10, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28793200/fasd-folic-acid-and-formic-acid-an-unholy-alliance-in-the-alcohol-abusing-mother
#14
Bhushan M Kapur, Marta Baber
Alcohol consumption during pregnancy remains a significant cause of preventable birth defects and developmental disabilities, however, the mechanism of toxicity remains unclear. Methanol is present as a congener in many alcoholic beverages and is formed endogenously. Since ethanol is preferentially metabolized over methanol, it has been found in the sera and CSF of alcoholics. Toxicity resulting from methanol has been attributed to formic acid. Formic acid is present in significantly higher quantities in biofluids of alcoholic patients...
August 9, 2017: Biochemistry and Cell Biology, Biochimie et Biologie Cellulaire
https://www.readbyqxmd.com/read/28792750/a-combined-ab-initio-kinetic-modeling-and-shock-tube-study-of-the-thermal-decomposition-of-ethyl-formate
#15
Hongbo Ning, Junjun Wu, Liuhao Ma, Wei Ren, David F Davidson, Ronald K Hanson
The potential energy surfaces (PESs) and reaction rate constants of the unimolecular decomposition of ethyl formate (EF) were investigated using high-precision theoretical methods at the CCSD(T)/CBS(T-Q)//M06-2x/6-311++G(d,p) level of theory. The calculated PESs of EF dissociation and molecular decomposition reactions prove that the intramolecular H-shift to produce formic acid and ethylene is the dominant decomposition pathway. A detailed chemical kinetic mechanism for EF pyrolysis was constructed by incorporating the important reactions of EF and its radicals into an existing mechanism previously developed for small methyl esters...
August 9, 2017: Journal of Physical Chemistry. A
https://www.readbyqxmd.com/read/28791806/ultra-high-performance-liquid-chromatography-coupled-with-electrospray-ionization-quadrupole-time-of-flight-mass-spectrometry-for-the-rapid-analysis-of-constituents-in-the-traditional-chinese-medicine-formula-wu-ji-bai-feng-pill
#16
Shengnan Duan, Wen Qi, Siwen Zhang, Kunkun Huang, Dan Yuan
An ultra high performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry method in both positive and negative ion modes was established in order to comprehensively investigate the major constituents in Wu-Ji-Bai-Feng-Pill. Briefly, a Waters ACQUITY UPLC HSS C18 column was used to separate the aqueous extract of Wu-Ji-Bai-Feng-Pill. 0.1% formic acid in acetonitrile and 0.1% aqueous formic acid v/v were used as the mobile phase. All analytes were determined using quadrupole time-of-flight mass spectrometry with electrospray ionization source in positive and negative ion modes...
August 9, 2017: Journal of Separation Science
https://www.readbyqxmd.com/read/28789798/development-of-a-validated-ultra-high-performance-liquid-chromatography-tandem-mass-spectrometry-method-for-determination-of-acid-diterpenes-in-copaifera-oleoresins
#17
Jonas Joaquim Mangabeira da Silva, Eduardo José Crevelin, Luiza Junqueira Carneiro, Hervé Rogez, Rodrigo Cassio Sola Veneziani, Sérgio Ricardo Ambrósio, Luiz Alberto Beraldo Moraes, Jairo Kenupp Bastos
Species of Copaifera genus (Fabaceae - Caesalpinoiodidaeae) produces an important commercial oleoresin that displays many medicinal properties. Copaifera oleoresins (COR) are composed mainly of a mixture of diterpenes and sequiterpenes, and the main reported acid diterpenes for this genus are kaurenoic, copalic, hardwickiic and polyaltic acids. An ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) method was developed and validated for identification and quantification of nine acid diterpenes...
July 12, 2017: Journal of Chromatography. A
https://www.readbyqxmd.com/read/28783000/multiclass-mycotoxin-analysis-in-edible-oils-using-a-simple-solvent-extraction-method-and-liquid-chromatography-with-tandem-mass-spectrometry
#18
Taeyong Eom, Hyun-Deok Cho, Junghyun Kim, Mihee Park, Jinyoung An, Moosung Kim, Sheen-Hee Kim, Sang Beom Han
A simple and rapid method for the simultaneous determination of eleven mycotoxins-aflatoxins B1, B2, G1, and G2; fumonisins B1, B2, and B3; ochratoxin A; zearalenone; deoxynivalenol; and T-2 toxin-in edible oils was established using liquid chromatography tandem mass spectrometry (LC-MS/MS). In this study, QuEChERS, QuEChERS with dispersive liquid-liquid microextraction, and solvent extraction were examined for sample preparation. Among these methods, solvent extraction with a mixture of formic acid/acetonitrile (5/95, v/v) successfully extracted all target mycotoxins...
August 7, 2017: Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment
https://www.readbyqxmd.com/read/28782031/a-spongy-nickel-organic-co2-reduction-photocatalyst-for-nearly-100-selective-co-production
#19
Kaiyang Niu, You Xu, Haicheng Wang, Rong Ye, Huolin L Xin, Feng Lin, Chixia Tian, Yanwei Lum, Karen C Bustillo, Marca M Doeff, Marc T M Koper, Joel Ager, Rong Xu, Haimei Zheng
Solar-driven photocatalytic conversion of CO2 into fuels has attracted a lot of interest; however, developing active catalysts that can selectively convert CO2 to fuels with desirable reaction products remains a grand challenge. For instance, complete suppression of the competing H2 evolution during photocatalytic CO2-to-CO conversion has not been achieved before. We design and synthesize a spongy nickel-organic heterogeneous photocatalyst via a photochemical route. The catalyst has a crystalline network architecture with a high concentration of defects...
July 2017: Science Advances
https://www.readbyqxmd.com/read/28780865/thermal-oxidation-degradation-of-2-2-4-4-tetrabromodiphenyl-ether-over-li%C3%AE-tiox-micro-nanostructures-with-the-dozens-of-oxidative-product-analysis-and-reaction-mechanism
#20
Qianqian Li, Guijin Su, Minghui Zheng, Mengjing Wang, Yalu Liu, Fang Luo, Yangyang Gu, Rong Jin
Flower-like LiαTiOx micro/nanostructures were successfully synthesized to degrade 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) at 250-350 °C. The pseudo-first-order kinetics rate constant of the reaction at 300 °C was in the range of 0.034-0.055 min-1. The activation energy was as low as 39.9-48.1 kJ/mol. The excellent performance attained over LiαTiOx was attributed to Li dopant having the electron-donating effect, which enhanced the oxygen specie mobility. The oxidative reaction was believed to be the dominant degradation pathway following Mars-van Krevelen mechanism, being accompanied by the weak hydrodebromination occurrence generating the trace mo- to tri-BDEs...
August 7, 2017: Environmental Science & Technology
keyword
keyword
109288
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"