Gastroesofagical reflux

Gastroesophageal reflux disease (GERD) often requires lifelong treatment to return to and maintain a normal quality of life. Proton pump inhibitors (PPIs) offer effective medical treatment and can be used for a long time with good safety margins. The diagnostic criteria for GERD must be strictly based on current guidelines and the need for maintained treatment must be regularly evaluated. When medical treatment fails (> 20%), the patient should be offered a consultation with a specialist in the field. Too many patients who are currently treated with PPI for suspected GERD ultimately require treatment with a completely different diagnosis in focus...

OBJECTIVE: Non-REM sleep is characterized by a physiologic oscillating pattern that exhibits different levels of arousal, coded as cyclic alternating pattern. The aim of this study was to analyze the development of cyclic alternating pattern parameters in a group of infants with apparent life-threatening events. METHODS: A total of 26 infants with apparent life-threatening events (14 females, mean age 3.4 months, 2.37 S.D., age range 0.5-9 months) were studied while they slept in the morning between feedings, by means of a 3-h video-electroencephalographic-polygraphic recording...

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AIM: Achalasia is a disease of unknown etiology resulting from degeneration of the esophageal Auerbach submucous plexus. This degeneration makes normal relaxation of the cardia during swallowing impossible leading to dysphagia, chest pain and regurgitation of varying degree. Until 15 years ago the main conservative treatment for achalasia was dilatation of the cardia with the Starck apparatus. Such approach to achalasia was usually reported as fairly effective, but complicated by an exceedingly high rate of perforation...

BACKGROUND: The allergic asthma is the reversible chronic inflammatory process at the airways, secondary to exaggerate reply to the allergens exposition, its treatment includes: avoiding the exposure to allergens, pharmacology therapy and the specific immunotherapy with allergens (ITA), which is based on the growing dosages of the extract allergenic; the objectives are to modify the immune response and to improve the allergic disease. The ITA can fail due to causes attributable to the patient, vaccine-inherent causes and/or factors related to the allergic disease...

The results on estimation of efficiency and safety of monotherapy by Rabeprasol in dose 20 mg per day in treatment of the gastroesophageal reflux disease in an open clinical investigation are presented. It was found 100% of Rabeprasol efficiency in healing of erosion and diffuse pathological changes of esophagus mucous at gastroesofageal reflux disease: in 18 from 20 patients--for 4 weeks (90%) and in one patient--for 8 weeks; ulcers of esophagus--for 8 weeks of treatment in one patient. This medicine showed safety use practically without any serious complications; the side effects were insignificant and did not require the cancellation or resort any other medications...

BACKGROUND: The association between bronchial asthma and gastroesofageal reflux provokes in the patient a reserved prognostic which if not diagnosed and treat correctly, if interferes of significative in the life quality. MATERIAL AND METHOD: With the purpose of establishing a relation between the allergic bronchial asthma of the adult, patient with digestive symptoms and healthy volunteer, is carried out a study in 162 subject with these characteristics to whom an barium esophagography was done looking for gastroesofageal reflux...