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https://www.readbyqxmd.com/read/28820654/locus-specific-dna-methylation-in-the-placenta-is-associated-with-levels-of-pro-inflammatory-proteins-in-cord-blood-and-they-are-both-independently-affected-by-maternal-smoking-during-pregnancy
#1
Sanne D van Otterdijk, Alexandra M Binder, Karin B Michels
We investigated the impact of maternal smoking during pregnancy on placental DNA methylation and how this may mediate the association between maternal smoking and pro-inflammatory proteins in cord blood. The study population consisted of 27 individuals exposed to maternal smoking throughout pregnancy, 32 individuals exposed during a proportion of the pregnancy, and 61 unexposed individuals. Methylation of 11 regions within 6 genes in placenta tissue was assessed by pyrosequencing. Levels of 7 pro-inflammatory proteins in cord blood were assessed by electrochemiluminescence...
August 18, 2017: Epigenetics: Official Journal of the DNA Methylation Society
https://www.readbyqxmd.com/read/28817951/cessation-related-information-motivation-and-behavioral-skills-in-smokers-living-with-hiv
#2
Daniel Shirley, Laura Thibodeau, Sheryl L Catz, Katryna McCoy, Douglas E Jorenby, Nasia Safdar, James M Sosman
There is a need for new, targeted smoking cessation interventions for smokers living with HIV. The Information-Motivation-Behavioral Skills (IMB) model has been applied effectively to HIV-related health behaviors and was used in this qualitative study to elicit factors that could lead to the development of innovative and successful cessation interventions for this population. Twenty individuals who smoked from two clinics providing care to people living with HIV participated in open-ended interviews, responding to questions covering the domains of the IMB model, as applied to smokers living with HIV...
August 17, 2017: AIDS Care
https://www.readbyqxmd.com/read/28817864/tobacco-cessation-strategies-it-takes-a-village
#3
Debbie Anne Chiu Qua
Smoking is the leading cause of preventable death and chronic diseases in the U.S. Identifying smokers and providing appropriate intervention is therefore an integral part of each clinic visit. A combination of pharmacotherapy as well as behavioral counseling provides the best results. Pharmacotherapy includes nicotine replacement (patch, gum, lozenges), bupropion and varenicline. More recently, electronic nicotinic delivery systems (such as e-cigarettes, vaporizers/vape pens, and hookah pens) have become popular...
2017: South Dakota Medicine: the Journal of the South Dakota State Medical Association
https://www.readbyqxmd.com/read/28817320/tobacco-industry-research-on-nicotine-replacement-therapy-if-anyone-is-going-to-take-away-our-business-it-should-be-us
#4
Dorie Apollonio, Stanton A Glantz
Nicotine replacement therapy (NRT) is recommended for tobacco cessation on the basis of pharmaceutical industry research showing its effectiveness when combined with counseling. The tobacco industry opposed NRT when it first appeared in the 1980s but by 2016 was marketing its own NRT products. We used internal tobacco industry documents dated 1960 through 2010 to identify the industry's perceptions of NRT. As early as the 1950s, tobacco companies developed nonsmoked nicotine replacements for cigarettes, but they stopped out of concern that marketing such products would trigger Food and Drug Administration regulation of cigarettes...
August 17, 2017: American Journal of Public Health
https://www.readbyqxmd.com/read/28816835/acute-worsening-of-tics-on-varenicline
#5
Shivam Om Mittal, Bryan T Klassen, Anhar Hassan, James H Bower, Elizabeth A Coon
OBJECTIVE: The aim of this study was to report worsening of Tourette syndrome (TS) in 2 patients treated with varenicline. BACKGROUND: Abnormal dopaminergic signaling is likely involved in the pathophysiology of TS. Varenicline is a partial α4β2 nicotinic acetylcholine agonist that enhances dopamine release. Therefore, the use of varenicline may influence tics in patients with TS. METHOD: We analyzed and described 2 case studies on patients with significant worsening of tics after treatment with varenicline...
August 14, 2017: Clinical Neuropharmacology
https://www.readbyqxmd.com/read/28816192/tobacco-abuse-and-associated-oral-lesions-among-interstate-migrant-construction-workers
#6
Anzil Ks Ali, Arshad Mohammed, Archana A Thomas, Shann Paul, M Shahul, K Kasim
AIM: The present study was conducted to assess the prevalence of tobacco use and associated oral mucosal lesions among construction workers of Cochin, Kerala, India. MATERIALS AND METHODS: A cross-sectional study was carried at various construction sites of Cochin and 2,163 workers were selected using multistage sampling method and were interviewed and examined. Information regarding demographic details, form, type, frequency of tobacco use, earlier attempt to quit, and willingness to quit tobacco use was obtained using predesigned questionnaire...
August 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28810494/development-and-validation-of-a-smoking-rationalization-scale-for-male-smokers-in-china
#7
Xinyuan Huang, Wenjie Fu, Haiying Zhang, Hong Li, Xiaoxia Li, Yong Yang, Fan Wang, Junling Gao, Pinpin Zheng, Hua Fu, Ding Ding, Simon Chapman
The purpose of this study is to develop a smoking rationalization scale for Chinese male smokers. A total of 35 focus groups and 19 one-on-one interviews were conducted to collect items of the scale. Exploratory factor analyses and confirmatory factor analyses were conducted to identify the underlying structure of the scale. Results found a 26-item scale within six dimensions (smoking functional beliefs, risk generalization beliefs, social acceptability beliefs, safe smoking beliefs, self-exempting beliefs, and quitting is harmful beliefs)...
July 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28810158/a-typology-of-vaping-identifying-differing-beliefs-motivations-for-use-identity-and-political-interest-amongst-e-cigarette-users
#8
Hannah Farrimond
BACKGROUND: The aim of this study was to identify and differentiate socially shared accounts of e-cigarette use (vaping) using Q-methodology, combining factor analysis with qualitative comments. METHODS: Seventy statements on e-cigarettes, drawn from media, academic and online discussions, were sorted by participants along a continuum of agreement/disagreement, commenting on strongly ranked items. Each participant thus created their own 'account' of their vaping...
August 12, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/28808692/treating-nicotine-dependence-and-preventing-smoking-relapse-in-cancer-patients
#9
Eun Hae Estelle Chang, Andrew Braith, Brian Hitsman, Robert A Schnoll
INTRODUCTION: Despite the well-documented harmful effects of smoking, many cancer patients continue to smoke. Smoking cessation is critical to address in this population given the associated increase in treatment toxicity, risk of second primary tumors, decrease in treatment response and higher disease-specific and all-cause mortality with continued smoking following a cancer diagnosis. This review seeks to summarize the latest recommendations and guidelines on smoking cessation treatment for patients diagnosed with cancer, and the evidence behind those recommendations...
2017: Expert Review of Quality of Life in Cancer Care
https://www.readbyqxmd.com/read/28806637/want-need-and-habit-as-drivers-of-smoking-behaviour-a-preliminary-analysis
#10
Luis Wehbe, Harveen Kaur Ubhi, Robert West
BACKGROUND AND AIMS: Models of tobacco smoking behaviour propose that anticipated pleasure or satisfaction, the need to alleviate a nicotine-induced drive state and a stimulus-driven impulse potentially play an important role. This study aimed to provide a preliminary assessment of how far urges to smoke are reported by smokers and whether the strength of such urges prior to a quit attempt predicts short-term success at quitting. METHODS: In a prospective study, 566 smokers attending a treatment programme to help smokers quit completed a written questionnaire covering frequency of different types of urge to smoke (automatic impulse - 'automatic urges', anticipated pleasure - 'pleasure urges', and fulfilling a need - 'need urges')...
July 19, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28804929/factors-moderating-the-relative-effectiveness-of-varenicline-and-nicotine-replacement-therapy-in-clients-using-smoking-cessation-services
#11
Neil Walker, Heather Gainforth, Vasiliki Kiparoglou, Hayley Robinson, Hugo van Woerden, Robert West
AIMS: To assess how far the greater effectiveness of varenicline over nicotine replacement therapy (NRT) is moderated by characteristics of the smokers or setting in clinical practice. DESIGN: We used observational data from 22,472 treatment episodes between 2013 and 2016 from smoking cessation services in England to assess whether differences between varenicline and NRT were moderated by a set of smoker and setting characteristics: these included level of social deprivation, age, gender, ethnic group, nicotine dependence, and treatment context...
August 13, 2017: Addiction
https://www.readbyqxmd.com/read/28802995/examining-the-high-rate-of-cigarette-smoking-among-adults-with-a-ged
#12
Charlotte A Schoenborn, Manfred Stommel, Jacqueline W Lucas
OBJECTIVES: We seek to identify characteristics of GED holders that explain their very high smoking rates compared with high school (HS) graduates. METHODS: We pooled data from the 2006-2014 National Health Interview Surveys (NHIS) for adults aged 25 and older (n=235,031) to describe cigarette smoking behaviors and smoking history for adults in six education categories, with a focus on comparing GED holders to HS graduates. Logistic regression was used to predict the odds of current cigarette smoking and successful quitting, accounting for demographic, employment, family/sociocultural, mental health, and other potential confounders...
April 19, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28802179/prevalence-of-population-smoking-cessation-by-electronic-cigarette-use-status-in-a-national-sample-of-recent-smokers
#13
Daniel P Giovenco, Cristine D Delnevo
INTRODUCTION: Amid decreasing rates of cigarette smoking and a rise in e-cigarette use, there is a need to understand population patterns of use to inform tobacco control efforts and evaluate whether e-cigarettes may play a role in tobacco harm reduction. METHODS: This study merged data from the 2014 and 2015 National Health Interview Survey (NHIS) and restricted the sample to recent smokers [i.e., current smokers and former smokers who quit in 2010 or later (n=15,532)]...
August 3, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28801792/electronic-cigarettes-and-awareness-of-their-health-effects
#14
A Daniluk, A Gawlikowska-Sroka, M Stępien-Słodkowska, E Dzięciołowska-Baran, K Michnik
The use of electronic cigarettes or e-cigarettes is strongly on the rise. The literature confirms that in the process of quitting smoking using an electronic device dispensing nicotine should be a transitional stage before the complete cessation of smoking. The aim of the present study was to assess the popularity of e-cigarettes, the underlying reasons for use of such nicotine products, and the level of awareness of health hazards associated with e-cigarettes. The study is of a survey type. The material consisted of data collected from an anonymous survey distributed among 46 female and 23 male users of e-cigarettes in 2015...
August 12, 2017: Advances in Experimental Medicine and Biology
https://www.readbyqxmd.com/read/28801403/equipping-community-pharmacy-workers-as-agents-for-health-behaviour-change-developing-and-testing-a-theory-based-smoking-cessation-intervention
#15
Liz Steed, Ratna Sohanpal, Wai-Yee James, Carol Rivas, Sandra Jumbe, Angel Chater, Adam Todd, Elizabeth Edwards, Virginia Macneil, Fraser Macfarlane, Trisha Greenhalgh, Chris Griffiths, Sandra Eldridge, Stephanie Taylor, Robert Walton
OBJECTIVE: To develop a complex intervention for community pharmacy staff to promote uptake of smoking cessation services and to increase quit rates. DESIGN: Following the Medical Research Council framework, we used a mixed-methods approach to develop, pilot and then refine the intervention. METHODS: Phase I: We used information from qualitative studies in pharmacies, systematic literature reviews and the Capability, Opportunity, Motivation-Behaviour framework to inform design of the initial version of the intervention...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28800182/development-and-preliminary-pilot-evaluation-of-a-brief-tablet-computer-intervention-to-motivate-tobacco-quitline-use-among-smokers-in-substance-use-treatment
#16
Richard A Brown, Jacki Hecht, Erika L Bloom, Haruka Minami, Christopher W Kahler, Ana M Abrantes, Mary E Dubreuil, Alan Gordon, Lawrence H Price, Steven J Ondersma
BACKGROUND AND OBJECTIVES: The majority of individuals in substance use disorder (SUD) treatment also smoke cigarettes; yet, the availability of smoking cessation services in SUD treatment remains limited. In this study, we developed and piloted a brief intervention for smokers in SUD treatment intended to motivate engagement in tobacco quitline treatment (TIME-TQ). METHODS: First, we interviewed 19 smokers in SUD treatment to inform the development of TIME-TQ (Phase 1)...
August 11, 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28797880/smoking-is-associated-with-earlier-time-to-revision-of-total-knee-arthroplasty
#17
Chin Tat Lim, Stuart B Goodman, James I Huddleston, Alex H S Harris, Subhrojyoti Bhowmick, William J Maloney, Derek F Amanatullah
BACKGROUND: Smoking is associated with early postoperative complications, increased length of hospital stay, and an increased risk of revision after total knee arthroplasty (TKA). However, the effect of smoking on time to revision TKA is unknown. METHODS: A total of 619 primary TKAs referred to an academic tertiary center for revision TKA were retrospectively stratified according to the patient smoking status. Smoking status was then analyzed for associations with time to revision TKA using a Chi square test...
August 7, 2017: Knee
https://www.readbyqxmd.com/read/28797399/a-54-year-old-man-with-anasarca-dyspnea-and-recurrent-bilateral-pleural-effusions
#18
Pradnya D Patil, Yvette M Cua, Carol Farver, Rafael L Perez, Atul C Mehta, Tanmay S Panchabhai
A 54-year-old African-American man presented with 2 years of progressively worsening dyspnea and anasarca. Over the past 6 months he gained 30 lbs with worsening lower extremity, abdominal wall, and scrotal edema. A recent workup for cardiac, renal, and liver disease, including two-dimensional echocardiogram, liver and renal function tests, and abdominal ultrasound, was unremarkable. He reported a 15-pack year history of smoking and quit 3 years ago. Chest radiograph at that time revealed bilateral pleural effusions that were both reportedly milky in appearance when drained by thoracenteses...
August 2017: Chest
https://www.readbyqxmd.com/read/28790545/smoking-cessation-advisory-intervention-in-patients-with-cardiovascular-disease
#19
Ioannis Vogiatzis, Alexandra Pantzartzidou, Sarantis Pittas, Eleutherios Papavasiliou
INTRODUCTION: Several studies have examined the efficacy of smoking cessation therapies in the general population. However little is known about the efficacy of these advisory methods in cardiovascular patients. AIM: The aim of the study is to determine the prevalence and the characteristics of smoking abstinence in cardiovascular patients, after a smoking intervention during hospitalization. METHODS: The study involved 442 patients, smokers admitted for cardiovascular disease to the Department of Cardiology...
April 2017: Medical Archives
https://www.readbyqxmd.com/read/28789980/use-of-higher-nicotine-tar-yield-regular-full-flavor-cigarettes-is-associated-with-nicotine-dependence-and-smoking-during-pregnancy-among-u-s-women
#20
Stephen T Higgins, Ryan Redner, Christopher A Arger, Allison N Kurti, Jeff S Priest, Janice Y Bunn
The present study examined full-flavor cigarette use among women of reproductive age to assess whether use is associated with greater nicotine dependence and smoking during pregnancy. We used data from the National Survey on Drug Use and Health (2005-2014). Consecutive years were combined to assure sufficient numbers of pregnant women. We examined whether use of full-flavor cigarettes was associated with greater odds of nicotine dependence using the Fagerstrom Test for Nicotine Dependence and Nicotine Dependence Syndrome Scale (NDSS), controlling for other smoking characteristics...
August 5, 2017: Preventive Medicine
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