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https://www.readbyqxmd.com/read/29761788/block-based-robust-control-of-stepping-using-intraspinal-microstimulation
#1
Ehsan Rouhani, Abbas Erfanian
OBJECTIVE: The problem of motor control using intraspinal microstimulation (ISMS) can be approached at two levels of the motor system: individual muscles (motor pools) and motor primitives. The major challenges of direct ISMS at the level of individual muscle are the number of electrodes that are required to be implanted in order to recruit all muscles involving the motion and the muscle selectivity. One solution to cope with these problems is the control of movement generated by appropriate combination of the movement primitives...
May 15, 2018: Journal of Neural Engineering
https://www.readbyqxmd.com/read/29751090/sex-dependent-and-sex-independent-muscle-activation-patterns-in-adult-gait-as-a-function-of-age
#2
Christopher A Bailey, Federica Corona, Giuseppina Pilloni, Micaela Porta, Maria Chiara Fastame, Paul Kenneth Hitchcott, Maria Pietronilla Penna, Massimiliano Pau, Julie N Côté
INTRODUCTION: Aging leads to poorer neuromuscular control that may impact mobility. However, the specific decades when these changes occur, and whether these time-based changes are sex-specific, are unclear. METHODS: Adults aged 20-82 years (N = 93, 51 females) walked six gait trials at their preferred speed over a 10-m platform. Electromyography (EMG) of the rectus femoris (RF), tibialis anterior (TA), and gastrocnemius lateralis (GL) were measured using wireless surface sensors...
May 8, 2018: Experimental Gerontology
https://www.readbyqxmd.com/read/29730490/increased-double-limb-support-times-during-walking-in-right-limb-dominant-healthy-older-adults-with-low-bone-density
#3
Paul S Sung
BACKGROUND: Older adults with low bone mineral density (BMD) may exhibit early markers for physical frailty; however, there is a lack of understanding of the dominant limb support patterns during walking. RESEARCH QUESTION: The purpose of this study was to investigate limb support times during walking in healthy older adults with low BMD. METHODS: Seventy-seven right limb dominant older adults (48 female subjects, 29 male subjects) participated in the study...
April 25, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29727777/centre-of-pressure-characteristics-during-walking-in-individuals-with-and-without-first-metatarsophalangeal-joint-osteoarthritis
#4
Hylton B Menz, Maria Auhl, Jade M Tan, Andrew K Buldt, Shannon E Munteanu
OBJECTIVE: The objective of this study was to compare centre of pressure characteristics during walking in individuals with and without first metatarsophalangeal joint osteoarthritis (1st MTPJ OA), in order to provide insights into alterations in foot function associated with this condition. METHODS: Twenty people with 1st MTPJ OA and 20 asymptomatic controls matched for age, sex and body mass index underwent gait analysis using the emed® -x400 plantar pressure system (Novel GmbH, Germany)...
April 26, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29683017/retrospective-evaluation-of-changes-in-gait-patterns-in-children-and-adolescents-with-cerebral-palsy-after-multilevel-surgery
#5
Ramona Steppacher, David North, Christoph Künzle, Harald Lengnick, Harry Klima, Annegret Mündermann, Regina Wegener
The purpose of this study was to retrospectively investigate changes in gait patterns after single-event multilevel surgery in children and adolescents with bilateral cerebral palsy. Three-dimensional instrumented pre- and postoperative gait data of 12 patients were compared to data of 12 healthy control subjects using principal component analysis to reduce the dimensionality of kinematic and kinetic gait data and detect gait differences. The differences between pre- and postoperative data and between postoperative data and data of control subjects were calculated using a linear mixed model...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29680436/distal-muscle-activity-alterations-during-the-stance-phase-of-gait-in-restless-leg-syndrome-rls-patients
#6
Chloe Dafkin, Andrew Green, Benita Olivier, Warrick McKinon, Samantha Kerr
OBJECTIVE: To assess if there is a circadian variation in electromyographical (EMG) muscle activity during gait in restless legs syndrome (RLS) patients and healthy control participants. METHODS: Gait assessment was done in 14 RLS patients and 13 healthy control participants in the evening (PM) and the morning (AM). Muscle activity was recorded bilaterally from the tibialis anterior (TA), lateral gastrocnemius (GL), rectus femoris (RF) and biceps femoris (BF) muscles...
May 2018: Sleep Medicine
https://www.readbyqxmd.com/read/29625268/trunk-muscle-activation-patterns-during-walking-among-persons-with-lower-limb-loss-influences-of-walking-speed
#7
Courtney M Butowicz, Julian C Acasio, Christopher L Dearth, Brad D Hendershot
Persons with lower limb amputation (LLA) walk with altered trunk-pelvic motions. The underlying trunk muscle activation patterns associated with these motions may provide insight into neuromuscular control strategies post LLA and the increased incidence of low back pain (LBP). Eight males with unilateral LLA and ten able-bodied controls (CTR) walked over ground at 1.0 m/s, 1.3 m/s, 1.6 m/s, and self-selected speeds. Trunk muscle onsets/offsets were determined from electromyographic activity of bilateral thoracic (TES) and lumbar (LES) erector spinae...
March 26, 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29603094/herc1-ubiquitin-ligase-is-required-for-normal-axonal-myelination-in-the-peripheral-nervous-system
#8
Sara Bachiller, María Angustias Roca-Ceballos, Irene García-Domínguez, Eva María Pérez-Villegas, David Martos-Carmona, Miguel Ángel Pérez-Castro, Luis Miguel Real, José Luis Rosa, Lucía Tabares, José Luis Venero, José Ángel Armengol, Ángel Manuel Carrión, Rocío Ruiz
A missense mutation in HERC1 provokes loss of cerebellar Purkinje cells, tremor, and unstable gait in tambaleante (tbl) mice. Recently, we have shown that before cerebellar degeneration takes place, the tbl mouse suffers from a reduction in the number of vesicles available for release at the neuromuscular junction (NMJ). The aim of the present work was to study to which extent the alteration in HERC1 may affect other cells in the nervous system and how this may influence the motor dysfunction observed in these mice...
March 30, 2018: Molecular Neurobiology
https://www.readbyqxmd.com/read/29587833/use-of-hybrid-assistive-limb-hal-%C3%A2-for-a-postoperative-patient-with-cerebral-palsy-a-case-report
#9
Yuki Mataki, Hiroshi Kamada, Hirotaka Mutsuzaki, Yukiyo Shimizu, Ryoko Takeuchi, Masafumi Mizukami, Kenichi Yoshikawa, Kazushi Takahashi, Mayumi Matsuda, Nobuaki Iwasaki, Hiroaki Kawamoto, Yasuyoshi Wadano, Yoshiyuki Sankai, Masashi Yamazaki
BACKGROUND: The Hybrid Assistive Limb (HAL® ) is an exoskeleton wearable robot suit that assists in voluntary control of knee and hip joint motion. There have been several studies on HAL intervention effects in stroke, spinal cord injury, and cerebral palsy. However, no study has investigated HAL intervention for patients with cerebral palsy after surgery. CASE PRESENTATION: We report a case of using HAL in a postoperative patient with cerebral palsy. A 15-year-old boy was diagnosed with spastic diplegia cerebral palsy Gross Motor Function Classification System level IV, with knee flection contracture, equinus foot, and paralysis of the right upper extremity with adduction contracture...
March 27, 2018: BMC Research Notes
https://www.readbyqxmd.com/read/29582777/a-simple-bipedal-model-for-studying-control-of-gait-termination
#10
Yasuyuki Suzuki, Hartmut Geyer
We study the control of human gait termination with a simple bipedal locomotion model. Several control strategies have been proposed for gait termination. However, the relative importance of these strategies has not been evaluated in models of human gait. Here we extend the bipedal spring mass walking model in a least parameter fashion and study three explicit control strategies for gait termination, including the shortening of the final step, braking at the ankle, and extending the knee. Applying the strategies separately, we find that only braking at the ankle reduces the propulsive force enough to transition into quiet standing...
March 27, 2018: Bioinspiration & Biomimetics
https://www.readbyqxmd.com/read/29581672/foot-pressure-analysis-of-gait-pattern-in-older-japanese-females-requiring-different-personal-care-support-levels
#11
Naoto Takayanagi, Motoki Sudo, Masahiko Fujii, Hirokazu Sakai, Keiko Morimoto, Masumi Tomisaki, Yoshifumi Niki, Ichiro Tokimitsu
[Purpose] This study evaluated gait parameters and foot pressure in two regions of the feet among older females with different personal care support needs to analyze factors that contribute to higher support requirements. [Subjects and Methods] Thirty-two older females were divided into support-need and care-need level groups. Gait parameters (speed, cadence, step length, step width, gait angle, toe angle, double support phase, swing phase, and stance phase) and foot pressure during a 5-m walk were measured and analyzed in the two groups...
March 2018: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/29544156/age-related-differences-in-segment-coordination-and-its-variability-during-gait
#12
Jocelyn F Hafer, Katherine A Boyer
BACKGROUND: Aging is associated with a loss of mobility and altered gait mechanics. Loss of function and mobility may be due to or exacerbated by low levels of physical activity in the aged. The mechanisms linking age-related changes in physiology, altered mobility and gait may be elucidated by examining movement coordination and coordination variability. RESEARCH QUESTION: The purpose of this study was to examine the impacts of age and habitual physical activity level on segment coordination and coordination variability during gait...
May 2018: Gait & Posture
https://www.readbyqxmd.com/read/29536559/abnormal-loading-of-the-hip-and-knee-joints-in-unilateral-hip-osteoarthritis-persists-two-years-after-total-hip-replacement
#13
Felix Stief, André Schmidt, Stefan van Drongelen, Katharina Lenarz, Dara Froemel, Timur Tarhan, Frederick Lutz, Andrea Meurer
A total hip replacement (THR) is a common and routine procedure to reduce pain and restore normal activity. Gait analysis can provide insights into functional characteristics and dynamic joint loading situation not identifiable by clinical examination or static radiographic measures. The present prospective longitudinal study tested whether 2 years after surgery a THR would restore dynamic loading of the knee and hip joints in the frontal plane to normal. Instrumented gait analysis was performed shortly before surgery and approximately 2 years after THR on 15 unilateral hip osteoarthritis (OA) patients...
March 14, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
https://www.readbyqxmd.com/read/29524851/gait-strategies-to-reduce-the-dynamic-joint-load-in-the-lower-limbs-during-a-loading-response-in-young-healthy-adults
#14
Toshiki Tajima, Hiroshige Tateuchi, Yumiko Koyama, Tome Ikezoe, Noriaki Ichihashi
Reducing external joint moments during gait can lead to a reduction in dynamic joint load. There has yet to be a detailed investigation of gait strategies that can reduce external joint moments by decreasing the magnitude of ground reaction force (GRF) without reducing the walking speed. The objectives of this study were to verify whether it is possible to reduce external joint moments by decreasing the GRF magnitude without reducing the walking speed and to identify the alternative walking strategy involved in young healthy adults...
April 2018: Human Movement Science
https://www.readbyqxmd.com/read/29517187/training-for-mobility-with-exoskeleton-robot-in-person-with-spinal-cord-injury-a-pilot-study
#15
Patrizio Sale, Emanuele F Russo, Alessandra Scarton, Rocco S Calabrò, Stefano Masiero, Serena Filoni
BACKGROUND: Wearable robots are people-oriented robots designed to be worn all day, thus helping in the daily activities. They can assist in walking, running, jumping higher or even lifting objects too heavy in normal conditions. AIM: The aim of this report was thus to investigate the change in gait pattern trough 3D gait analysis subjects with Spinal Cord Injury (PwSCI) that underwent an adaptive training with a wearable Exoskeletal Device (ESD). The change in the quality of life was also investigate together with the possibility to wear these devices all day, to improve the mobility...
March 7, 2018: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29486504/impact-of-hippotherapy-on-gross-motor-function-and-quality-of-life-in-children-with-bilateral-cerebral-palsy-a-randomized-open-label-crossover-study
#16
Ute Deutz, Nicole Heussen, Katharina Weigt-Usinger, Steffen Leiz, Christa Raabe, Tilman Polster, Steinbüchel Daniela, Christine Moll, Thomas Lücke, Ingeborg Krägeloh-Mann, Helmut Hollmann, Martin Häusler
This study investigated the effect of hippotherapy on gross motor function (Gross Motor Function Measure [GMFM]-66, GMFM dimension E and D) and quality of life (Child Health Questionnaire [CHQ 28], KIDSCREEN-27 parental versions) in children with bilateral spastic cerebral palsy. Seventy-three children (age: 9.1 ± 3.3 years; male = 44; GMFCS levels II = 27; III = 17; IV = 29) were randomized to an early ( n  = 35) or late ( n  = 38) treatment group. Data from 66 probands were available for further analysis...
June 2018: Neuropediatrics
https://www.readbyqxmd.com/read/29475131/factors-affecting-premature-plantarflexor-muscle-activity-during-hemiparetic-gait
#17
Kazuki Fujita, Hiroichi Miaki, Akira Fujimoto, Hideaki Hori, Hitomi Fujimoto, Yasutaka Kobayashi
In hemiparetic stroke survivors, premature plantarflexor muscle activity (PPF) often appears as a gait abnormality from terminal swing to the loading response on the paretic side. This study aimed to discern factors giving rise to PPF. Lower extremity function, spasticity magnitude, and gait electromyograms were assessed in 31 hemiparetic stroke survivors. Mean amplitudes during gait phases were determined for the paretic soleus, tibialis anterior, rectus femoris, and biceps femoris. The subjects were classified into PPF and non-PPF groups based on their relative soleus amplitude at different phases of gait, and group differences in each measurement were calculated and subjected to logistic regression...
April 2018: Journal of Electromyography and Kinesiology
https://www.readbyqxmd.com/read/29457532/effects-of-real-time-gait-biofeedback-on-paretic-propulsion-and-gait-biomechanics-in-individuals-post-stroke
#18
Katlin Genthe, Christopher Schenck, Steven Eicholtz, Laura Zajac-Cox, Steven Wolf, Trisha M Kesar
Objectives Gait training interventions that target paretic propulsion induce improvements in walking speed and function in individuals post-stroke. Previously, we demonstrated that able-bodied individuals increase propulsion unilaterally when provided real-time biofeedback targeting anterior ground reaction forces (AGRF). The purpose of this study was to, for the first time, investigate short-term effects of real-time AGRF gait biofeedback training on post-stroke gait. Methods Nine individuals with post-stroke hemiparesis (6 females, age = 54 ± 12...
April 2018: Topics in Stroke Rehabilitation
https://www.readbyqxmd.com/read/29441131/centre-of-pressure-characteristics-in-normal-planus-and-cavus-feet
#19
Andrew K Buldt, Saeed Forghany, Karl B Landorf, George S Murley, Pazit Levinger, Hylton B Menz
Background: The aim of this study was to compare centre of pressure (COP) characteristics between healthy adults with normal, planus or cavus feet who were allocated to groups based on reliable foot posture measurement techniques. Methods: Ninety-two healthy adult participants (aged 18 to 45) were recruited and classified as either normal ( n  = 35), pes planus ( n  = 31) or pes cavus ( n  = 26) based on Foot Posture Index, Arch Index and normalised navicular height truncated measurements...
2018: Journal of Foot and Ankle Research
https://www.readbyqxmd.com/read/29427102/spinocerebellum-ataxia-type-6-molecular-mechanisms-and-calcium-channel-genetics
#20
Xiaofei Du, Christopher Manuel Gomez
Spinocerebellar ataxia (SCA) type 6 is an autosomal dominant disease affecting cerebellar degeneration. Clinically, it is characterized by pure cerebellar dysfunction, slowly progressive unsteadiness of gait and stance, slurred speech, and abnormal eye movements with late onset. Pathological findings of SCA6 include a diffuse loss of Purkinje cells, predominantly in the cerebellar vermis. Genetically, SCA6 is caused by expansion of a trinucleotide CAG repeat in the last exon of longest isoform CACNA1A gene on chromosome 19p13...
2018: Advances in Experimental Medicine and Biology
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