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gait termination

Jocelyn F Hafer, Katherine A Boyer
BACKGROUND: Aging is associated with a loss of mobility and altered gait mechanics. Loss of function and mobility may be due to or exacerbated by low levels of physical activity in the aged. The mechanisms linking age-related changes in physiology, altered mobility and gait may be elucidated by examining movement coordination and coordination variability. RESEARCH QUESTION: The purpose of this study was to examine the impacts of age and habitual physical activity level on segment coordination and coordination variability during gait...
February 26, 2018: Gait & Posture
Felix Stief, André Schmidt, Stefan van Drongelen, Katharina Lenarz, Dara Froemel, Timur Tarhan, Frederick Lutz, Andrea Meurer
A total hip replacement (THR) is a common and routine procedure to reduce pain and restore normal activity. Gait analysis can provide insights into functional characteristics and dynamic joint loading situation not identifiable by clinical examination or static radiographic measures. The present prospective longitudinal study tested whether two years after surgery a THR would restore dynamic loading of the knee and hip joints in the frontal plane to normal. Instrumented gait analysis was performed shortly before surgery and approximately two years after THR on 15 unilateral hip osteoarthritis patients...
March 14, 2018: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Toshiki Tajima, Hiroshige Tateuchi, Yumiko Koyama, Tome Ikezoe, Noriaki Ichihashi
Reducing external joint moments during gait can lead to a reduction in dynamic joint load. There has yet to be a detailed investigation of gait strategies that can reduce external joint moments by decreasing the magnitude of ground reaction force (GRF) without reducing the walking speed. The objectives of this study were to verify whether it is possible to reduce external joint moments by decreasing the GRF magnitude without reducing the walking speed and to identify the alternative walking strategy involved in young healthy adults...
March 7, 2018: Human Movement Science
Patrizio Sale, Emanuele F Russo, Alessandra Scarton, Rocco S Calabrò, Stefano Masiero, Serena Filoni
BACKGROUND: Wearable robots are people-oriented robots designed to be worn all day, thus helping in the daily activities. They can assist in walking, running, jumping higher or even lifting objects too heavy in normal conditions. AIM: The aim of this report was thus to investigate the change in gait pattern trough 3D gait analysis subjects with Spinal Cord Injury (PwSCI) that underwent an adaptive training with a wearable Exoskeletal Device (ESD). The change in the quality of life was also investigate together with the possibility to wear these devices all day, to improve the mobility...
March 7, 2018: European Journal of Physical and Rehabilitation Medicine
Ute Deutz, Nicole Heussen, Katharina Weigt-Usinger, Steffen Leiz, Christa Raabe, Tilman Polster, Steinbüchel Daniela, Christine Moll, Thomas Lücke, Ingeborg Krägeloh-Mann, Helmut Hollmann, Martin Häusler
This study investigated the effect of hippotherapy on gross motor function (Gross Motor Function Measure [GMFM]-66, GMFM dimension E and D) and quality of life (Child Health Questionnaire [CHQ 28], KIDSCREEN-27 parental versions) in children with bilateral spastic cerebral palsy. Seventy-three children (age: 9.1 ± 3.3 years; male = 44; GMFCS levels II = 27; III = 17; IV = 29) were randomized to an early ( n  = 35) or late ( n  = 38) treatment group. Data from 66 probands were available for further analysis...
February 27, 2018: Neuropediatrics
Kazuki Fujita, Hiroichi Miaki, Akira Fujimoto, Hideaki Hori, Hitomi Fujimoto, Yasutaka Kobayashi
In hemiparetic stroke survivors, premature plantarflexor muscle activity (PPF) often appears as a gait abnormality from terminal swing to the loading response on the paretic side. This study aimed to discern factors giving rise to PPF. Lower extremity function, spasticity magnitude, and gait electromyograms were assessed in 31 hemiparetic stroke survivors. Mean amplitudes during gait phases were determined for the paretic soleus, tibialis anterior, rectus femoris, and biceps femoris. The subjects were classified into PPF and non-PPF groups based on their relative soleus amplitude at different phases of gait, and group differences in each measurement were calculated and subjected to logistic regression...
February 14, 2018: Journal of Electromyography and Kinesiology
Katlin Genthe, Christopher Schenck, Steven Eicholtz, Laura Zajac-Cox, Steven Wolf, Trisha M Kesar
Objectives Gait training interventions that target paretic propulsion induce improvements in walking speed and function in individuals post-stroke. Previously, we demonstrated that able-bodied individuals increase propulsion unilaterally when provided real-time biofeedback targeting anterior ground reaction forces (AGRF). The purpose of this study was to, for the first time, investigate short-term effects of real-time AGRF gait biofeedback training on post-stroke gait. Methods Nine individuals with post-stroke hemiparesis (6 females, age = 54 ± 12...
February 19, 2018: Topics in Stroke Rehabilitation
Andrew K Buldt, Saeed Forghany, Karl B Landorf, George S Murley, Pazit Levinger, Hylton B Menz
Background: The aim of this study was to compare centre of pressure (COP) characteristics between healthy adults with normal, planus or cavus feet who were allocated to groups based on reliable foot posture measurement techniques. Methods: Ninety-two healthy adult participants (aged 18 to 45) were recruited and classified as either normal ( n  = 35), pes planus ( n  = 31) or pes cavus ( n  = 26) based on Foot Posture Index, Arch Index and normalised navicular height truncated measurements...
2018: Journal of Foot and Ankle Research
Xiaofei Du, Christopher Manuel Gomez
Spinocerebellar ataxia (SCA) type 6 is an autosomal dominant disease affecting cerebellar degeneration. Clinically, it is characterized by pure cerebellar dysfunction, slowly progressive unsteadiness of gait and stance, slurred speech, and abnormal eye movements with late onset. Pathological findings of SCA6 include a diffuse loss of Purkinje cells, predominantly in the cerebellar vermis. Genetically, SCA6 is caused by expansion of a trinucleotide CAG repeat in the last exon of longest isoform CACNA1A gene on chromosome 19p13...
2018: Advances in Experimental Medicine and Biology
Keisuke Uemura, Penny R Atkins, Niccolo M Fiorentino, Andrew E Anderson
BACKGROUND: Individuals are thought to compensate for femoral anteversion by altering hip rotation. However, the relationship between hip rotation in a neutral position (i.e. static rotation) and dynamic hip rotation is poorly understood, as is the relationship between anteversion and hip rotation. RESEARCH OBJECTIVE: Herein, anteversion and in-vivo hip rotation during standing, walking, and pivoting were measured in eleven asymptomatic, morphologically normal, young adults using three-dimensional computed tomography models and dual fluoroscopy...
January 29, 2018: Gait & Posture
Na-Xi Tian, Yu Xu, Jin-Yu Yang, Lu Li, Xiao-Hong Sun, Yun Wang, Ying Zhang
Potassium voltage-gated channel interacting protein 3 (KChIP3), also termed downstream regulatory element antagonist modulator (DREAM) and calsenilin, is a multifunctional protein belonging to the neuronal calcium sensor (NCS) family. Recent studies revealed the expression of KChIP3 in dorsal root ganglion (DRG) neurons, suggesting the potential role of KChIP3 in peripheral sensory processing. Herein, we show that KChIP3 colocalizes with transient receptor potential ion channel V1 (TRPV1), a critical molecule involved in peripheral sensitization during inflammatory pain...
February 14, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Gema Chamorro-Moriana, Antonio José Moreno, José Luis Sevillano
This systematic review synthesized and analyzed clinical findings related to the effectiveness of innovative technological feedback for tackling functional gait recovery. An electronic search of PUBMED, PEDro, WOS, CINAHL, and DIALNET was conducted from January 2011 to December 2016. The main inclusion criteria were: patients with modified or abnormal gait; application of technology-based feedback to deal with functional recovery of gait; any comparison between different kinds of feedback applied by means of technology, or any comparison between technological and non-technological feedback; and randomized controlled trials...
January 6, 2018: Sensors
Giampiero I Baroncelli, Elena Ferretti, Cecilia M Pini, Benedetta Toschi, Rita Consolini, Silvano Bertelloni
Camurati-Engelmann disease (CED) is an ultrarare autosomal dominant bone dysplasia. Cortical thickening of the diaphyses of the long bones with narrowing of the medullary cavity are associated with bone pain, waddling gait, muscular weakness, easy fatigability, and a marfanoid body habitus. There is no specific treatment for CED. Nonsteroidal anti-inflammatory drugs or glucocorticoids are ineffective in improving bone lesions. A family with a mild to severe form of CED is described. Two patients received long-term bisphosphonate treatment: the 19-year-old female proband was treated with zoledronic acid for 2...
November 2017: Molecular Syndromology
Su-Hyun Lee, Hwang-Jae Lee, Won Hyuk Chang, Byung-Ok Choi, Jusuk Lee, Jeonghun Kim, Gyu-Ha Ryu, Yun-Hee Kim
BACKGROUND: A robotic exoskeleton device is an intelligent system designed to improve gait performance and quality of life for the wearer. Robotic technology has developed rapidly in recent years, and several robot-assisted gait devices were developed to enhance gait function and activities of daily living in elderly adults and patients with gait disorders. In this study, we investigated the effects of the Gait-enhancing Mechatronic System (GEMS), a new wearable robotic hip-assist device developed by Samsung Electronics Co, Ltd...
November 28, 2017: Journal of Neuroengineering and Rehabilitation
T Brunel, S Lobet, K Deschamps, C Hermans, K Peerlinck, J Vandesande, J-B Pialat
OBJECTIVES: To assess the reliability of the IPSG MRI scale for tibiotalar (TTJ) and subtalar joint (STJ) changes in young haemophilic patients, correlating MRI findings with functional scores and 3D-rearfoot kinematics. METHODS: A total of 37 haemophilic patients underwent bilateral MRI of the footankle, clinical evaluation and quantitative assessment of their 3D-rearfoot kinematics during walking. TTJ and STJ soft tissues were assessed twice along with osteochondral changes by two radiologists using the IPSG MRI scale...
November 23, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
L B Suckling, D Stephensen, M C Cramp, R Mahaffey, W I Drechsler
INTRODUCTION: Improvements in the medical management for those with haemophilia have resulted in improved clinical outcomes. However, current treatment regimens do not alleviate all joint haemarthroses with the potential for long-term joint deterioration remaining. The evaluation of functional activities such as gait, using standardized tools to monitor children with haemophilia is emerging. AIM: This study explored differences in sagittal plane biomechanics of walking in adolescent boys aged 11-18 years with haemophilia and an age-matched group of typically developing boys...
November 17, 2017: Haemophilia: the Official Journal of the World Federation of Hemophilia
Aline A Gomes, Marko Ackermann, Jean P Ferreira, Maria Isabel V Orselli, Isabel C N Sacco
BACKGROUND: Muscle force estimation could advance the comprehension of the neuromuscular strategies that diabetic patients adopt to preserve walking ability, which guarantees their independence as they deal with their neural and muscular impairments due to diabetes and neuropathy. In this study, the lower limb's muscle force distribution during gait was estimated and compared in diabetic patients with and without polyneuropathy. METHODS: Thirty individuals were evaluated in a cross-sectional study, equally divided among controls (CG) and diabetic patients with (DNG) and without (DG) polyneuropathy...
November 9, 2017: Journal of Neuroengineering and Rehabilitation
Patrick L Garcia, Mohammed I Hossain, Shaida A Andrabi, Charles N Falany
Sulfotransferase 4A1 (SULT4A1) belongs to the cytosolic sulfotransferase (SULT) superfamily of enzymes that catalyze sulfonation reactions with a variety of endogenous and exogenous substrates. Of the SULTs, SULT4A1 was shown to have the highest sequence homology between vertebrate species, yet no known function or enzymatic activity have been identified for this orphan SULT. To better understand SULT4A1 function in mammalian brain, two mutant SULT4A1 mouse strains were generated utilizing CRISPR-Cas9 technology...
November 6, 2017: Drug Metabolism and Disposition: the Biological Fate of Chemicals
Lorenzo Rum, Luca Laudani, Andrea Macaluso, Giuseppe Vannozzi
Transitory tasks, such as gait termination, involve interactions between neural and biomechanical factors that challenge postural stability and head stabilization patterns in older adults. The aim of the study was to compare upper body patterns of acceleration during planned gait termination at different speeds between young and older women. Ten young and 10 older women were asked to carry out three gait termination trials at slow, comfortable and fast speed. A stereophotogrammetric system and a 15-body segments model were used to calculate antero-posterior whole-body Center of Mass (AP CoM) speed and to reconstruct the centroids of head, trunk and pelvis segments...
October 25, 2017: Journal of Biomechanics
Tateo Warabi, Hiroyasu Furuyama, Eri Sugai, Masamichi Kato, Nobuo Yanagisawa
This study examined how gait bradykinesia is changed by the motor programming in Parkinson's disease. Thirty-five idiopathic Parkinson's disease patients and nine age-matched healthy subjects participated in this study. After the patients fixated on a visual-fixation target (conditioning-stimulus), the voluntary-gait was triggered by a visual on-stimulus. While the subject walked on a level floor, soleus, tibialis anterior EMG latencies, and the y-axis-vector of the sole-floor reaction force were examined. Three paradigms were used to distinguish between the off-/on-latencies...
October 27, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
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