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https://www.readbyqxmd.com/read/28735780/electromyographic-activity-of-the-vastus-intermedius-muscle-in-patients-with-stiff-knee-gait-after-stroke-a-retrospective-observational-study
#1
Davide Mazzoli, Erika Giannotti, Mario Manca, Maria Longhi, Paolo Prati, Michela Cosma, Giovanni Ferraresi, Monica Morelli, Paolo Zerbinati, Stefano Masiero, Andrea Merlo
Stiff-knee gait (SKG) in hemiplegic patients is often due to an inappropriate activity of the quadriceps femoris. However, there are no studies in literature addressing the vastus intermedius (VI) involvement in SKG. In this study, VI activity was analyzed in a sample of 46 chronic stroke patients with SKG, during spontaneous gait. VI activity was recorded by fine-wire electrodes inserted under ultrasound guidance then confirmed by electrical stimulation. The measured VI activity was compared to the normal reference pattern reported in literature and classified (e...
July 5, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28732757/multimodal-exercise-training-in-multiple-sclerosis-a-randomized-controlled-trial-in-persons-with-substantial-mobility-disability
#2
Brian M Sandroff, Rachel E Bollaert, Lara A Pilutti, Melissa L Peterson, Tracy Baynard, Bo Fernhall, Edward McAuley, Robert W Motl
BACKGROUND: Mobility disability is a common, debilitating feature of multiple sclerosis (MS). Exercise training has been identified as an approach to improve MS-related mobility disability. However, exercise randomized controlled trials (RCTs) on mobility in MS have generally not selectively targeted those with the onset of irreversible mobility disability. OBJECTIVES: The current multi-site RCT compared the efficacy of 6-months of supervised, multimodal exercise training with an active control condition for improving mobility, gait, physical fitness, and cognitive outcomes in persons with substantial MS-related mobility disability...
July 18, 2017: Contemporary Clinical Trials
https://www.readbyqxmd.com/read/28723276/can-an-app-help-identify-psychomotor-function-impairments-during-drinking-occasions-in-the-real-world-a-mixed-method-pilot-study
#3
Brian Suffoletto, Akash Goyal, Juan Carlos Puyana, Tammy Chung
BACKGROUND: Being able to measure the acute effects of alcohol consumption on psychomotor functions in natural settings could be useful in injury prevention interventions. This study examined the feasibility and acceptability of collecting app-based measures of information processing, working memory and gait stability during times of typical alcohol consumption among young adults. METHODS: Ten young adults (aged 21-26) with hazardous drinking completed a baseline assessment and ecological momentary assessments (EMA) on 4 consecutive Fridays and Saturdays, every hour from 8pm to 12am...
July 19, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28719564/the-new-apgar-score-a-checklist-to-enhance-quality-of-life-in-geriatric-patients-with-hip-fracture
#4
Joseph Bernstein, Sara Weintraub, Eric Hume, Mark D Neuman, Stephen L Kates, Jaimo Ahn
For geriatric patients with hip fractures, the broken bone is the reason for admission, but only part of the overall disease. Indeed, it may be more helpful to consider the patient having geriatric hip fracture syndrome or sustaining a hip attack, as there are many associated medical, social, psychological, and other problems to which attention must be paid. To that end, we have identified a series of 10 steps, collected into a checklist, that can be undertaken for all patients with geriatric hip fracture. In homage to the maxim "we come into the world under the brim of the pelvis and go out through the neck of the femur," we defined our checklist by the acronym APGAR SCORE, named after the classic checklist of the same name used to assess a newborn child...
July 19, 2017: Journal of Bone and Joint Surgery. American Volume
https://www.readbyqxmd.com/read/28715936/selection-of-gait-parameters-for-differential-diagnostics-of-patients-with-de-novo-parkinson-s-disease
#5
Milica Djurić-Jovičić, Minja Belić, Iva Stanković, Saša Radovanović, Vladimir S Kostić
BACKGROUND: Gait disturbances are an integral part of clinical manifestations of Parkinson's disease (PD), even in the initial stages of the disease. Our goal was to identify the set of spatio-temporal gait parameters that bear the highest relevance for characterizing de novo PD patients. METHODS: Forty patients with de novo PD and forty healthy controls were recorded while walking over an electronic walkway in three different conditions: (1) base walking, (2) walking with an additional motor task, (3) walking with an additional mental task...
July 17, 2017: Neurological Research
https://www.readbyqxmd.com/read/28713254/short-term-effects-of-thoracic-spine-manipulation-on-the-biomechanical-organisation-of-gait-initiation-a-randomized-pilot-study
#6
Sébastien Ditcharles, Eric Yiou, Arnaud Delafontaine, Alain Hamaoui
Speed performance during gait initiation is known to be dependent on the capacity of the central nervous system to generate efficient anticipatory postural adjustments (APA). According to the posturo-kinetic capacity (PKC) concept, any factor enhancing postural chain mobility and especially spine mobility, may facilitate the development of APA and thus speed performance. "Spinal Manipulative Therapy High-Velocity, Low-Amplitude" (SMT-HVLA) is a healing technique applied to the spine which is routinely used by healthcare practitioners to improve spine mobility...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28685649/misdiagnosis-cns-erdheim-chester-disease-mimicking-clippers
#7
Jillian Berkman, Caleb Ford, Emily Johnson, Beth A Malow, Joseph M Aulino
Introduction Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is an inflammatory central nervous system (CNS) disorder with particular involvement of the pons. Diagnostic criteria include a range of clinical symptoms related to the underlying brainstem pathology, visible with magnetic resonance imaging (MRI). MRI findings include the appearance of punctuate and curvilinear gadolinium enhancement 'peppering' the pons. We discuss a patient presenting with clinical and radiographic characteristics of CLIPPERS who was diagnosed with Erdheim-Chester disease (ECD)...
January 1, 2017: Neuroradiology Journal
https://www.readbyqxmd.com/read/28683418/tibial-impact-accelerations-in-gait-of-primary-school-children-the-effect-of-age-and-speed
#8
Oren Tirosh, Guy Orland, Alon Eliakim, Dan Nemet, Nili Steinberg
Tibial stress fractures are associated with increased lower extremity loading at initial foot-ground contact, reflected in high peak positive acceleration (>8g) of the tibia in adults. There is no reported data on peak positive acceleration of the tibia in children during walking and running. The aim of this study was to establish tibial peak positive acceleration responses in children across a range of age and gait speeds. Twenty-four children aged 8.5±1.4years with no known gait pathology comprised two age groups; Young (7-9year, n=12) and Older (10-12 years, n=12)...
June 27, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28680006/vertebral-fracture-at-the-caudal-end-of-a-surgical-fusion-for-thoracic-vertebral-fracture-in-a-patient-with-diffuse-idiopathic-skeletal-hyperostosis-dish
#9
Hiroshi Kobayashi, Koji Otani, Kazuyuki Watanabe, Kinshi Kato, Takuya Nikaido, Shoji Yabuki, Shin-Ichi Kikuchi, Shin-Ichi Konno
The patient was an 86-year-old woman with back pain after a fall. She had no neurological findings at the initial visit. Plain radiographs and magnetic resonance imaging (MRI) showed diffuse idiopathic skeletal hyperostosis (DISH) and a Th10 fracture. Two weeks later, she started gait exercise with immobilization by a rigid orthosis. Twenty-five days later, she presented with paralysis and numbness of her legs. Computed tomography (CT) showed anterior expansion in the vertebral body of Th10. MRI showed an intramedullary high-intensity area on T2-weighted images at the same level...
July 5, 2017: Fukushima Journal of Medical Science
https://www.readbyqxmd.com/read/28675421/associations-between-self-reported-physical-activity-and-physical-performance-measures-over-time-in-postmenopausal-women-the-women-s-health-initiative
#10
Deepika R Laddu, Betsy C Wertheim, David O Garcia, Robert Brunner, Erik Groessl, Aladdin H Shadyab, Scott B Going, Michael J LaMonte, Brad Cannell, Meryl S LeBoff, Jane A Cauley, Cynthia A Thomson, Marcia L Stefanick
OBJECTIVES: To examine prospective associations between changes in physical activity (PA) and changes in physical performance measures (PPMs) over 6 years in older women. DESIGN: Prospective cohort study. SETTING: Forty clinical centers in the United States. PARTICIPANTS: Women aged 65 and older (mean age 69.8) enrolled in the Women's Health Initiative Clinical Trials with gait speed, timed chair stand, grip strength, and self-reported recreational PA data assessed at baseline (1993-98) and follow-up Years 1, 3, and 6 (N = 5,092)...
July 4, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28674364/diffuse-cerebral-vasoconstriction-in-a-intravascular-lymphoma-patient-with-a-high-serum-mpo-anca-level
#11
Atsuhiko Sugiyama, Makoto Kobayashi, Ayaka Daizo, Miyako Suzuki, Hirotoshi Kawashima, Shin-Ichiro Kagami, Hiroaki Tanaka, Yoshio Suzuki, Takashi Matsunaga, Satoshi Kuwabara
An 87-year-old woman presented with a 3-month history of fever, edema of the lower legs, and gait disturbance. A laboratory examination revealed high serum levels of myeloperoxidase-specific antineutrophil cytoplasmic antibody (MPO-ANCA). Although microscopic polyangiitis was initially suspected and treated, the patient subsequently developed transient hemiparesis and disturbed consciousness. Brain magnetic resonance imaging/angiography revealed infarct-like lesions, pachymeningeal involvement, and diffuse cerebral vasoconstriction...
2017: Internal Medicine
https://www.readbyqxmd.com/read/28673716/contribution-of-the-supplementary-motor-area-and-the-cerebellum-to-the-anticipatory-postural-adjustments-and-execution-phases-of-human-gait-initiation
#12
Aliénor Richard, Angèle Van Hamme, Xavier Drevelle, Jean-Louis Golmard, Sabine Meunier, Marie-Laure Welter
Several brain structures including the brainstem, the cerebellum and the frontal cortico-basal ganglia network, with the primary and premotor areas have been shown to participate in the functional organization of gait initiation and postural control in humans, but their respective roles remain poorly understood. The aim of this study was to better understand the role of the supplementary motor area (SMA) and posterior cerebellum in the gait initiation process. Gait initiation parameters were recorded in 22 controls both before and after continuous theta burst transcranial stimulation (cTBS) of the SMA and cerebellum, and were compared to sham stimulation, using a randomized double-blind design study...
July 1, 2017: Neuroscience
https://www.readbyqxmd.com/read/28672154/gait-adaptations-with-aging-in-healthy-participants-and-people-with-knee-joint-osteoarthritis
#13
Lynsey D Duffell, Stevan J Jordan, Justin P Cobb, Alison H McGregor
The relationship between age and gait characteristics in people with and without medial compartment osteoarthritis (OA) remains unclear. We aimed to characterize this relationship and to relate biomechanical and structural parameters in a subset of OA patients. Twenty five participants with diagnosed unilateral medial knee OA and 84 healthy participants, with no known knee pathology were recruited. 3D motion capture was used to analyse sagittal and coronal plane gait parameters while participants walked at a comfortable speed...
June 21, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28671116/motor-phenotype-in-neurodegenerative-disorders-gait-and-balance-platform-study-design-protocol-for-the-ontario-neurodegenerative-research-initiative-ondri
#14
Manuel Montero-Odasso, Frederico Pieruccini-Faria, Rob Bartha, Sandra E Black, Elizabeth Finger, Morris Freedman, Barry Greenberg, David A Grimes, Robert A Hegele, Christopher Hudson, Peter W Kleinstiver, Anthony E Lang, Mario Masellis, Paula M McLaughlin, Douglas P Munoz, Stephen Strother, Richard H Swartz, Sean Symons, Maria Carmela Tartaglia, Lorne Zinman, Michael J Strong, William McIlroy
BACKGROUND: The association of cognitive and motor impairments in Alzheimer's disease and other neurodegenerative diseases is thought to be related to damage in the common brain networks shared by cognitive and cortical motor control processes. These common brain networks play a pivotal role in selecting movements and postural synergies that meet an individual's needs. Pathology in this "highest level" of motor control produces abnormalities of gait and posture referred to as highest-level gait disorders...
June 27, 2017: Journal of Alzheimer's Disease: JAD
https://www.readbyqxmd.com/read/28666514/a-rare-neuropsychiatric-presentation-of-adult-onset-wilson-s-disease
#15
Ather Muneer
Wilson's disease is characterised by deposition of copper in various tissues of the body, most markedly in the liver and the brain. Cerebral involvement, evident as neuropsychiatric symptoms, may be the presenting form of the illness in up to 50% of the adults. When patients present initially with psychiatric manifestations, the correct diagnosis is frequently missed. This case report describes an adult in his late 20's who presented with symptoms of major depressive disorder, but failed to respond to standard antidepressant treatment...
November 2016: Journal of the College of Physicians and Surgeons—Pakistan: JCPSP
https://www.readbyqxmd.com/read/28663349/a-nationwide-cohort-study-of-slipped-capital-femoral-epiphysis
#16
Daniel C Perry, David Metcalfe, Matthew L Costa, Tjeerd Van Staa
OBJECTIVES: To describe the epidemiology of slipped capital femoral epiphysis (SCFE), to examine associations with childhood obesity and socioeconomic deprivation, and to explore factors associated with diagnostic delays. DESIGN: Historic cohort study using linked primary and secondary care data from the Clinical Practice Research Datalink and Hospital Episode Statistics. SETTING: All contacts with healthcare services, including emergency presentations, outpatient appointments, inpatient admissions and primary care visits, within the UK National Health Service...
June 29, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28662423/biomechanical-research-on-contour-cage-with-transacetabular-screws-fixation-in-revision-total-hip-arthroplasty
#17
Haobo Wu, Chiyuan Ma, Jisheng Ran, Danfeng Xu, An Liu, Miao Sun, Lidong Wu, Shigui Yan
BACKGROUND: Use biomechanical technique to access the strain distribution and stability of Contour anti-protrusion cage with or without the whole circumference acetabular cup fixation by the transacetabular screws. METHODS: Pelvic specimens from 10 male cadavers were used for the biomechanical test. The models of type C bone defect were copied according to the AAOS classification. Group 1: the contour reconstruction ring was fixed only by flange screws; Group 2: the contour reconstruction ring was fixed both by flange screws and transacetabular screws in dome...
June 21, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28660359/non-alcoholic-wernicke-s-encephalopathy-with-cortical-involvement-and-polyneuropathy-following-gastrectomy
#18
Wei-Chia Tsao, Long-Sun Ro, Chiung-Mei Chen, Hong-Chiu Chang, Hung-Chou Kuo
In this study, we present the clinical manifestations, brain magnetic resonance imaging (MRI) and concurrent polyneuropathies in two patients with non-alcoholic Wernicke's encephalopathy (WE) after gastrojejunostomy (Billroth II) anastomosis procedures. These patients developed sub-acute onset of disorientation and disturbance of consciousness following several weeks of poor intake. Peripheral neuropathy of varying severity was noted before and after the onset of WE. Brain MRI of the patients showed cerebellar vermis and symmetric cortical abnormalities in addition to typical WE changes...
June 28, 2017: Metabolic Brain Disease
https://www.readbyqxmd.com/read/28659774/electromyographic-pattern-during-gait-initiation-differentiates-yoga-practitioners-among-physically-active-older-subjects
#19
Thierry Lelard, Pierre-Louis Doutrellot, Abdou Temfemo, Said Ahmaidi
During gait initiation, postural adjustments are needed to deal with balance and movement. With aging, gait initiation changes and reflects functional degradation of frailty individuals. However, physical activities have demonstrated beneficial effects of daily motor tasks. The aim of our study was to compare center of pressure (COP) displacement and ankle muscle co-activation during gait initiation in two physically active groups: a group of walkers (n = 12; mean age ± SD 72.6 ± 3.2 years) and a yoga group (n = 11; 71...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28659154/spinocerebellar-ataxia-type-29-due-to-mutations-in-itpr1-a-case-series-and-review-of-this-emerging-congenital-ataxia
#20
Jessica L Zambonin, Allison Bellomo, Hilla Ben-Pazi, David B Everman, Lee M Frazer, Michael T Geraghty, Amy D Harper, Julie R Jones, Benjamin Kamien, Kristin Kernohan, Mary Kay Koenig, Matthew Lines, Elizabeth Emma Palmer, Randal Richardson, Reeval Segel, Mark Tarnopolsky, Jason R Vanstone, Melissa Gibbons, Abigail Collins, Brent L Fogel, Tracy Dudding-Byth, Kym M Boycott
BACKGROUND: Spinocerebellar ataxia type 29 (SCA29) is an autosomal dominant, non-progressive cerebellar ataxia characterized by infantile-onset hypotonia, gross motor delay and cognitive impairment. Affected individuals exhibit cerebellar dysfunction and often have cerebellar atrophy on neuroimaging. Recently, missense mutations in ITPR1 were determined to be responsible. RESULTS: Clinical information on 21 individuals from 15 unrelated families with ITPR1 mutations was retrospectively collected using standardized questionnaires, including 11 previously unreported singletons and 2 new patients from a previously reported family...
June 28, 2017: Orphanet Journal of Rare Diseases
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