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https://www.readbyqxmd.com/read/28324959/a-robotic-exoskeleton-to-treat-crouch-gait-from-cerebral-palsy-initial-kinematic-and-neuromuscular-evaluation
#1
Zachary F Lerner, Diane L Damiano, Thomas C Bulea
A robotic exoskeleton was designed for individuals with crouch gait caused by cerebral palsy with the intent to supplement existing muscle function during walking. The aim of this study was to evaluate how powered knee extension assistance provided during stance and swing phases of the gait cycle affect knee kinematics, and knee flexor and extensor muscle activity. Muscle activity and kinematic data were collected from four individuals with crouch gait from cerebral palsy during their normal walking condition and while walking with the exoskeleton under stance, swing, and stance & swing assistance...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28318948/comparative-assessment-of-intrinsic-mechanical-stimuli-on-knee-cartilage-and-compressed-agarose-constructs
#2
A Completo, C Bandeiras, F Fonseca
A well-established cue for improving the properties of tissue-engineered cartilage is mechanical stimulation. However, the explicit ranges of mechanical stimuli that correspond to favorable metabolic outcomes are elusive. Usually, these outcomes have only been associated with the applied strain and frequency, an oversimplification that can hide the fundamental relationship between the intrinsic mechanical stimuli and the metabolic outcomes. This highlights two important key issues: the firstly is related to the evaluation of the intrinsic mechanical stimuli of native cartilage; the second, assuming that the intrinsic mechanical stimuli will be important, deals with the ability to replicate them on the tissue-engineered constructs...
March 17, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28306641/a-kinematic-symmetry-index-of-gait-pattern-between-older-adults-with-and-without-low-back-pain
#3
Paul S Sung, Pamela Danial
STUDY DESIGN: Cross-sectional study. OBJECTIVE: To investigate the symmetry index for limb support patterns in right limb dominant older adults with and without low back pain (LBP). SUMMARY OF BACKGROUND DATA: The effects of bilateral asymmetry on gait performance were reported; however, there is a lack of understanding on kinematic symmetry to assess subjects with LBP. This asymmetry might be related to increased compensatory patterns to the dominant side in subjects with LBP...
March 16, 2017: Spine
https://www.readbyqxmd.com/read/28302314/a-new-measure-of-trip-risk-integrating-minimum-foot-clearance-and-dynamic-stability-across-the-swing-phase-of-gait
#4
Brian W Schulz
Minimum toe clearance (MTC) is thought to quantify the risk of the toe contacting the ground during the swing phase of gait and initiating a trip, but there are methodological issues with this measure and the risk of trip-related falls has been shown to also be associated with gait speed and dynamic stability. This paper proposes and evaluates a new measure, trip risk integral (TRI), that circumvents many issues with MTC as typically calculated at a single point by considering minimum foot clearance across the entire swing phase and taking into account dynamic stability to estimate risk of falling due to a trip rather than risk of the foot contacting the floor...
February 27, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28299643/retention-of-the-first-trial-effect-in-gait-slip-among-community-living-older-adults
#5
Xuan Liu, Tanvi Bhatt, Shuaijie Wang, Feng Yang, Yi-Chung Clive Pai
"First-trial effect" characterizes the rapid adaptive behavior that changes the performance outcome (from fall to non-fall) after merely a single exposure to postural disturbance. The purpose of this study was to investigate how long the first-trial effect could last. Seventy-five (≥ 65 years) community-dwelling older adults, who were protected by an overhead full body harness system, were retested for a single slip 6-12 months after their initial exposure to a single gait-slip. Subjects' body kinematics that was used to compute their proactive (feedforward) and reactive (feedback) control of stability was recorded by an eight-camera motion analysis system...
February 2017: Geroscience
https://www.readbyqxmd.com/read/28295612/relationship-between-pre-transplant-physical-function-and-outcomes-after-kidney-transplant-elizabeth
#6
C Lorenz, Andrea L Cheville, Hatem Amer, Brian R Kotajarvi, Mark D Stegall, Tanya M Petterson, Walter K Kremers, Fernando G Cosio, Nathan K LeBrasseur
BACKGROUND: Performance-based measures of physical function predict morbidity following non-transplant surgery. Study objectives were to determine whether physical function predicts outcomes after kidney transplant and assess how physical function changes post-transplant. METHODS: We conducted a prospective study involving living donor kidney transplants recipients at our center 5/2012 to 2/2014. Physical function was measured using the Short Physical Performance Battery (SPPB) (balance, chair stands, gait speed) and grip strength testing...
March 11, 2017: Clinical Transplantation
https://www.readbyqxmd.com/read/28293760/effects-of-partial-absence-of-visual-feedback-information-on-gait-symmetry
#7
Seung-Jae Kim, Marie Aimee Kayitesi, Amy Chan, Kimberli Graham
The incorporation of real-time visual feedback during gait rehabilitation can improve the efficacy of training. Our prior work demonstrated that the imposed distortion of simple visual feedback information of step lengths entails an unintentional adaptive process in the subjects' spatial gait pattern, thereby suggesting the important role of implicit learning in the context of gait rehabilitation that employs visual feedback. The purpose of this study was to investigate whether the removal of a portion of visual feedback information-after it had initially been provided-had any impact on gait symmetry...
March 14, 2017: Applied Psychophysiology and Biofeedback
https://www.readbyqxmd.com/read/28293475/nationwide-hospital-based-survey-of-idiopathic-normal-pressure-hydrocephalus-in-japan-epidemiological-and-clinical-characteristics
#8
Nagato Kuriyama, Masakazu Miyajima, Madoka Nakajima, Michiko Kurosawa, Wakaba Fukushima, Yoshiyuki Watanabe, Etsuko Ozaki, Yoshio Hirota, Akiko Tamakoshi, Etsuro Mori, Takeo Kato, Takahiko Tokuda, Akinori Urae, Hajime Arai
OBJECTIVES: There have been no nationwide epidemiological studies of idiopathic normal pressure hydrocephalus (iNPH) in Japan. Therefore, a nationwide epidemiologic survey of iNPH was performed to determine the number of cases and clinical characteristics by sex and diagnostic level. METHODS: The first survey examined the numbers of cases that met the diagnostic criteria of iNPH and those who underwent shunt operations in 2012. The second survey gathered patients' details to clarify their clinical background characteristics...
March 2017: Brain and Behavior
https://www.readbyqxmd.com/read/28291737/advantages-of-eeg-phase-patterns-for-the-detection-of-gait-intention-in-healthy-and-stroke-subjects
#9
Andreea Ioana Sburlea, Luis Montesano, Javier Minguez
OBJECTIVE: One use of EEG-based brain-computer interfaces (BCIs) in rehabilitation is the detection of movement intention. In this paper we investigate for the first time the instantaneous phase of movement related cortical potential (MRCP) and its application to the detection of gait intention. APPROACH: We demonstrate the utility of MRCP phase in two independent datasets, in which 10 healthy subjects and 9 chronic stroke patients executed a self-initiated gait task in three sessions...
March 14, 2017: Journal of Neural Engineering
https://www.readbyqxmd.com/read/28291395/prospective-evaluation-of-intra-articular-dextrose-prolotherapy-for-treatment-of-osteoarthritis-in-dogs
#10
J Matthew Sherwood, James K Roush, Laura J Armbrust, Walter C Renberg
The objective of this study was to evaluate intra-articular dextrose prolotherapy for osteoarthritis of the elbow or stifle in dogs in a randomized, double-blind, placebo-controlled, prospective pilot study. Seventeen dogs were evaluated with 10 meeting inclusion criteria for this study. Evaluations included orthopedic exam, visual lameness scoring, Canine Brief Pain Inventory (CBPI), goniometry, kinetic gait analysis, and radiography. Initial lameness score, age, body weight, duration of lameness, and CBPI scores did not differ between groups...
March 14, 2017: Journal of the American Animal Hospital Association
https://www.readbyqxmd.com/read/28289642/therapeutic-effect-of-microcurrent-therapy-in-children-with-in-toeing-gait-caused-by-increased-femoral-anteversion-a-pilot-study
#11
Jae Ki Ahn, Dong Rak Kwon, Gi-Young Park, Ki-Hoon Lee, Jae Hwal Rim, Won Bin Jung, Dae Gil Kwon
OBJECTIVE: To investigate the efficacy of portable microcurrent therapy device (PMTD) of the hip internal rotators in the treatment of in-toeing gait caused by increased femoral anteversion in children over 8 years of age. METHODS: Eleven children (22 legs; 4 boys and 7 girls; mean age, 10.4±1.6 years) with in-toeing gait caused by increased femoral anteversion were included in the present study. All children received 60 minutes of PMTD (intensity, 25 µA; frequency, 8 Hz) applied to the hip internal rotators daily for 4 weeks...
February 2017: Annals of Rehabilitation Medicine
https://www.readbyqxmd.com/read/28284667/center-of-pressure-and-center-of-mass-behavior-during-gait-initiation-on-inclined-surfaces-a-statistical-parametric-mapping-analysis
#12
Marcus Fraga Vieira, Ademir Alves de Brito, Georgia Cristina Lehnen, Fábio Barbosa Rodrigues
This study analyzed gait initiation (GI) on inclined surfaces with 68 young adult subjects of both sexes. Ground reaction forces and moments were collected using two AMTI force platforms, of which one was in a horizontal position and the other was inclined by 8% in relation to the horizontal plane. Departing from a standing position, each participant executed three trials in the following conditions: horizontal position (HOR), inclined position at ankle dorsi-flexion (UP), and inclined position at ankle plantar-flexion (DOWN)...
February 27, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28284572/an-articulated-ankle-foot-orthosis-with-adjustable-plantarflexion-resistance-dorsiflexion-resistance-and-alignment-a-pilot-study-on-mechanical-properties-and-effects-on-stroke-hemiparetic-gait
#13
Toshiki Kobayashi, Michael S Orendurff, Grace Hunt, Lucas S Lincoln, Fan Gao, Nicholas LeCursi, K Bo Foreman
Mechanical properties of an articulated ankle-foot orthosis (AFO) are closely related to gait performance in individuals post-stroke. This paper presents a pilot study on the mechanical properties of a novel articulated AFO with adjustable plantarflexion resistance, dorsiflexion resistance and alignment, and its effect on ankle and knee joint kinematics and kinetics in an individual post-stroke during gait. The mechanical properties of the AFO were quantified. Gait analysis was performed using a 3D motion capture system with a split-belt instrumented treadmill under 12 different settings of the mechanical properties of the AFO [i...
March 8, 2017: Medical Engineering & Physics
https://www.readbyqxmd.com/read/28282629/manganese-exposure-and-neurotoxic-effects-in-children
#14
REVIEW
Geir Bjørklund, Max Stanley Chartrand, Jan Aaseth
Manganese (Mn) is the fifth most abundant metal on earth. Although it is a well understood essential trace element, in excess, Mn is neurotoxic. Initial toxic symptoms associated with Mn are of psychiatric nature and are clinically defined as locura manganica. Neurological signs of Mn toxicity include dystonia, progressive bradykinesia, and disturbance of gait, slurring, and stuttering of speech with diminished volume. Studies indicate that children who ingested Mn in the drinking water (WMn) at or above a level of 0...
March 7, 2017: Environmental Research
https://www.readbyqxmd.com/read/28279852/effectiveness-of-surgical-and-non-surgical-management-of-crouch-gait-in-cerebral-palsy-a-systematic-review
#15
REVIEW
Scott A Galey, Zachary F Lerner, Thomas C Bulea, Seymour Zimbler, Diane L Damiano
BACKGROUND: Cerebral palsy (CP) is a prevalent group of neuromotor disorders caused by early injury to brain regions or pathways that control movement. Patients with CP exhibit a range of functional motor disabilities and pathologic gait patterns. Crouch gait, characterized by increased knee flexion throughout stance, is a common gait pattern in CP that increases energy costs of walking and contributes to ambulatory decline. Our aim was to perform the first systematic literature review on the effectiveness of interventions utilized to ameliorate crouch gait in CP...
February 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28275124/a-modelling-approach-to-the-dynamics-of-gait-initiation
#16
Manish Anand, Justin Seipel, Shirley Rietdyk
Gait initiation is an integral and complex part of human locomotion. In this paper, we present a novel compliant-leg model-based approach to understanding the key phases of initiation, the nature of the effective forces involved in initiation, and the importance of the anticipatory postural adjustments (APAs). The results demonstrate that in the presence of APAs, we observe a change in the characteristic of forcing required for initiation, and the energetic cost of gait initiation is also reduced by approximately 58%...
March 2017: Journal of the Royal Society, Interface
https://www.readbyqxmd.com/read/28272726/-measurement-of-the-outcomes-in-acquired-brain-injury-in-a-neurorehabilitation-unit-a-long-term-study
#17
V Cruz-Guisado, P Diaz-Borrego, B Romero-Romero, M Rodriguez-Pinero Duran
INTRODUCTION: Following sudden brain damage, there is a loss of capabilities that affects the person's autonomy. Recovery from the physical, psychic and cognitive sequelae requires the application of multiple therapies, the outcomes of which need to be measured objectively. Our aim is to analyse the application of standardised instruments in determining the therapeutic outcomes in acquired brain injury. PATIENTS AND METHODS: We conducted a retrospective descriptive observational study lasting 13 months...
March 16, 2017: Revista de Neurologia
https://www.readbyqxmd.com/read/28271220/constraints-on-perception-of-information-from-obstacles-during-foot-clearance-in-people-with-chronic-stroke
#18
Mohsen Shafizadeh, Jonathan Wheat, Keith Davids, Noureddin Nakhostin Ansari, Ali Ali, Samira Garmabi
The aim of this study was to examine effects of different types of task constraints on coupling of perception and action in people with chronic stroke when crossing obstacles during a walking task. Ten participants with hemiplegic chronic stroke volunteered to walk over a static obstacle under two distinct task constraints: simple and dual tasks. Under simple task constraints, without specific instructions, participants walked at their preferred speed and crossed over an obstacle. Under dual task constraints, the same individuals were required to subtract numbers whilst walking...
March 7, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28271039/deep-multi-scale-location-aware-3d-convolutional-neural-networks-for-automated-detection-of-lacunes-of-presumed-vascular-origin
#19
Mohsen Ghafoorian, Nico Karssemeijer, Tom Heskes, Mayra Bergkamp, Joost Wissink, Jiri Obels, Karlijn Keizer, Frank-Erik de Leeuw, Bram van Ginneken, Elena Marchiori, Bram Platel
Lacunes of presumed vascular origin (lacunes) are associated with an increased risk of stroke, gait impairment, and dementia and are a primary imaging feature of the small vessel disease. Quantification of lacunes may be of great importance to elucidate the mechanisms behind neuro-degenerative disorders and is recommended as part of study standards for small vessel disease research. However, due to the different appearance of lacunes in various brain regions and the existence of other similar-looking structures, such as perivascular spaces, manual annotation is a difficult, elaborative and subjective task, which can potentially be greatly improved by reliable and consistent computer-aided detection (CAD) routines...
2017: NeuroImage: Clinical
https://www.readbyqxmd.com/read/28270636/-adult-onset-neuronal-intranuclear-inclusion-disease-in-two-female-siblings
#20
Takeshi Yoshimoto, Kazuhiro Takamatsu, Takashi Kurashige, Jun Sone, Gen Sobue, Masaru Kuriyama
Neuronal intranuclear inclusion disease (NIID) in two adult siblings (both women, aged 76 and 68 years) is reported on here. The elder sister had a resting tremor and bradykinesia at age 66 years, and treatment with L-DOPA was initiated(L-3, 4-dihydroxyphenylalanine). Three years later, she showed a frozen gait that was associated with the medication wearing off. The clinical manifestations did not improve with the administration of antiparkinson drugs. Six years later, she showed impaired cognitive functions, which had occured gradually, and she began to take donepezil...
March 2017: Brain and Nerve, Shinkei Kenkyū No Shinpo
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