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https://www.readbyqxmd.com/read/28628551/a-clinical-framework-for-functional-recovery-in-a-person-with-chronic-traumatic-brain-injury-a-case-study
#1
Karen McCain, Staci Shearin
BACKGROUND AND PURPOSE: This case study describes a task-specific training program for gait walking and functional recovery in a young man with severe chronic traumatic brain injury. CASE DESCRIPTION: The individual was a 26-year-old man 4 years post-traumatic brain injury with severe motor impairments who had not walked outside of therapy since his injury. He had received extensive gait training prior to initiation of services. His goal was to recover the ability to walk...
July 2017: Journal of Neurologic Physical Therapy: JNPT
https://www.readbyqxmd.com/read/28620575/osteoporosis-management-in-ankylosing-spondylitis
#2
Alicia M Hinze, Grant H Louie
Low bone mineral density (BMD) is increasingly recognized as a common comorbid condition in ankylosing spondylitis (AS). As low BMD increases fracture risk, it is important to identify and treat low BMD in patients with AS who have been shown to be at increased risk for fractures above the population normal. Since low BMD occurs early in disease, we screen during the first year of diagnosis with dual energy x-ray absorptiometry (DXA). If patients are found to have osteoporosis by T-score of less than -2.5 or if their Z-score on DXA is more than two standard deviations below the mean, we initiate therapy with bisphosphonates in males and in females who are not planning any future pregnancies...
December 2016: Current Treatment Options in Rheumatology
https://www.readbyqxmd.com/read/28616033/exercise-induced-muscle-fatigue-in-the-unaffected-knee-joint-and-its-influence-on-postural-control-and-lower-limb-kinematics-in-stroke-patients
#3
Sun Wook Park, Sung Min Son, Na Kyung Lee
This study aimed to investigate the effects of exercise-induced muscle fatigue in the unaffected knee joint on postural control and kinematic changes in stroke patients. Forty participants (20 stroke patients, 20 age-matched healthy participants) were recruited. To induce fatigue, maximum voluntary isometric contractions were performed in the unaffected knee joint in a Leg Extension Rehab exercise machine using the pneumatic resistance. We measured static and dynamic balance and lower-limb kinematics during gait...
May 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28601293/from-dizziness-to-severe-ataxia-and-dysarthria-new-cases-of-anti-ca-arhgap26-autoantibody-associated-cerebellar-ataxia-suggest-a-broad-clinical-spectrum
#4
Ulrike Wallwitz, Sebastian Brock, Antje Schunck, Brigitte Wildemann, Sven Jarius, Frank Hoffmann
In 2010, a novel anti-neuronal autoantibody, termed anti-Ca, was described in a patient with subacute cerebellar ataxia, and Rho GTPase-activating protein 26 (ARHGAP26) was identified as the target antigen. Recently, three additional cases of anti-Ca-positive cerebellar ataxia have been published. In addition to ataxia, cognitive decline and depression have been observed in some patients. Here, we report two new cases of anti-Ca-associated autoimmune cerebellar ataxia. Patient 1 presented with dizziness and acute yet mild limb and gait ataxia...
August 15, 2017: Journal of Neuroimmunology
https://www.readbyqxmd.com/read/28599157/comparison-in-three-dimensional-gait-kinematics-between-young-and-older-adults-on-land-and-in-shallow-water
#5
Khalid Abdul Jabbar, Shigetada Kudo, Kee Wee Goh, Ming Rong Goh
This study investigated in three-dimensional space, firstly whether the aquatic medium and secondly ageing, had any effect on the lower limb's joint angles during aquatic-based gait. Three-dimensional joint kinematics of the lower limb of 51 healthy male participants [25 young group (24.6±4.9 years, 172.1±5.5cm, 69.8±10.3kg) and 26 older group (58.5±5.1 years, 167.9±5.1cm, 70.8±12.1kg)] were quantified during land and shallow water walking. Participants walked at their self-selected comfortable speed in both mediums...
May 20, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28596214/changes-in-mechanical-work-during-neural-adaptation-to-asymmetric-locomotion
#6
Brian P Selgrade, Montakan Thajchayapong, Gloria E Lee, Megan E Toney, Young-Hui Chang
Minimizing whole body metabolic cost has been suggested to drive the neural processes of locomotor adaptation. Mechanical work performed by the legs should dictate the major changes in whole body metabolic cost of walking while providing greater insight into temporal and spatial mechanisms of adaptation. We hypothesized changes in mechanical work by the legs during an asymmetric split-belt walking adaptation task could explain previously observed changes in whole body metabolic cost. We predicted subjects would immediately increase mechanical work performed by the legs when first exposed to split-belt walking, followed by a gradual decrease throughout adaptation...
June 8, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28583674/three-dimensional-data-tracking-dynamic-optimization-simulations-of-human-locomotion-generated-by-direct-collocation
#7
Yi-Chung Lin, Marcus G Pandy
The aim of this study was to perform full-body three-dimensional (3D) dynamic optimization simulations of human locomotion by driving a neuromusculoskeletal model toward in vivo measurements of body-segmental kinematics and ground reaction forces. Gait data were recorded from 5 healthy participants who walked at their preferred speeds and ran at 2m/s. Participant-specific data-tracking dynamic optimization solutions were generated for one stride cycle using direct collocation in tandem with an OpenSim-MATLAB interface...
May 19, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28583462/decreased-anticipatory-postural-adjustments-during-gait-initiation-acutely-post-concussion
#8
Thomas A Buckley, Jessie R Oldham, Barry A Munkasy, Kelsey E Evans
OBJECTIVE: The purpose of this study was to investigate anticipatory postural adjustments (APA) during the transitional movement task of gait initiation (GI) in individuals acutely following a concussion. DESIGN: Cohort Study. SETTING: University Research Center. PARTICIPANTS: A population based sample of 84 participants divided into two equal groups of acutely post-concussion (CONC) and healthy student athletes. INTERVENTION: Participants were tested on two occasions - a pre-injury baseline test and then the CONC group was retested acutely post-concussion and the control group again at a similar time...
June 2, 2017: Archives of Physical Medicine and Rehabilitation
https://www.readbyqxmd.com/read/28582688/a-simplified-pressure-adjustment-clinical-pathway-for-programmable-valves-in-nph-patients
#9
Tracy S Ma, Nikhil Sharma, M Sean Grady
OBJECTIVE: The goal of this study is to provide a clinical pathway for shunt valve adjustment in the treatment of normal pressure hydrocephalus (NPH) patients. PATIENT AND METHODS: The authors conducted a single-center retrospective study of 102 patients (mean age 74 years, 66 men, 36 women) diagnosed with NPH. In all cases, a Medtronic Strata Adjustable Pressure valve set initially at 1.5 was implanted. Outcome was based on the clinical status of the patient at the last contact point with the senior author...
May 30, 2017: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28582260/a-personalized-self-management-rehabilitation-system-for-stroke-survivors-a-quantitative-gait-analysis-using-a-smart-insole
#10
Richard John Davies, Jack Parker, Paul McCullagh, Huiru Zheng, Chris Nugent, Norman David Black, Susan Mawson
BACKGROUND: In the United Kingdom, stroke is the single largest cause of adult disability and results in a cost to the economy of £8.9 billion per annum. Service needs are currently not being met; therefore, initiatives that focus on patient-centered care that promote long-term self-management for chronic conditions should be at the forefront of service redesign. The use of innovative technologies and the ability to apply these effectively to promote behavior change are paramount in meeting the current challenges...
November 8, 2016: JMIR Rehabil Assist Technol
https://www.readbyqxmd.com/read/28574938/chronic-anterior-pelvic-instability-diagnosis-and-management
#11
Michael D Stover, Adam I Edelstein, Joel M Matta
Chronic anterior pelvic ring instability can cause pain and disability. Pain typically is localized to the suprapubic area or inner thigh; often is associated with lower back or buttock pain; and may be exacerbated by activity, direct impact, or pelvic ring compression. Known etiologies of chronic anterior pelvic ring instability include pregnancy, parturition, trauma, insufficiency fractures, athletics, prior surgery, and osteitis pubis. Diagnosis often is delayed. Physical examination may reveal an antalgic or waddling gait, tenderness over the pubic bones or symphysis pubis, and pain with provocative maneuvers...
June 1, 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/28573372/a-survey-of-anatomical-items-relevant-to-the-practice-of-rheumatology-pelvis-lower-extremity-and-gait
#12
Cristina Hernández-Díaz, José Alvarez-Nemegyei, José Eduardo Navarro-Zarza, Pablo Villaseñor-Ovies, Robert A Kalish, Juan J Canoso, Angélica Vargas, Karla Chiapas-Gasca, Joseph J Biundo, Francisco Javier de Toro Santos, Dennis McGonagle, Simon Carette, Miguel Ángel Saavedra
This study aimed to generate a minimum list of structural and functional anatomical items about the pelvis/hip, knee, ankle/foot, gait, and lower limb innervation, which are most relevant to the practice of rheumatology. To determine their perceived relevance to clinical practice, seven members of the Mexican Clinical Anatomy Task Force compiled an initial list of 470 anatomical items. Ten local and international experts according to a 0-10 Likert scale ranked these items. Of the original list, 101 (21.48%) items were considered relevant (global rate >40)...
June 1, 2017: Clinical Rheumatology
https://www.readbyqxmd.com/read/28559759/chiropractic-care-of-a-10-year-old-boy-with-nonorganic-gait-disorder-a-case-report
#13
David E Wasylynko
OBJECTIVE: The purpose of this case report is to describe the multidisciplinary management of a boy with nonorganic gait disorder. CLINICAL FEATURES: A 10-year-old boy presented to a chiropractic clinic having had a concussion 1 week prior. He presented with lower limb muscle weakness and ataxia while weight bearing. He was referred immediately to the emergency department, from which he was sent to a neurologist at a children's hospital. The neurologist's diagnosis was nonorganic gait disorder...
June 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/28549648/characterization-of-long-term-gait-deficits-in-mouse-dmcao-using-the-catwalk-system
#14
E Caballero-Garrido, J C Pena-Philippides, Z Galochkina, E Erhardt, T Roitbak
Evaluation of functional outcome is widely used across species to assess the recovery process following various pathological conditions, including spinal cord injury, musculo-skeletal injury, mithochondrial disease, neuropathic cancer, Huntington's disease, chronic pain, cortical lesion, and olivocerebellar degeneration among others. The Stroke Therapy Academic Industry Roundtable (STAIR) recommends multiple endpoints for behavioral studies in pre-clinical stroke research, to demonstrate their clinical relevance...
May 23, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28538514/long-term-outcome-of-4-patients-with-transcobalamin-deficiency-caused-by-2-novel-tcn2-mutations
#15
Marwan Nashabat, Gustavo Maegawa, Peter H Nissen, Ebba Nexo, Hussain Al-Shamrani, Mohammed Al-Owain, Majid Alfadhel
Cobalamin (vitamin B12 [Cbl]) is an essential cofactor for many biochemical pathways. Transcobalamin (TC) is required to internalize Cbl into the cells through membrane receptor-mediated endocytosis. Cbl is then processed in the cytoplasm and mitochondria by complementation factors leading to its active metabolites; methylcobalamin and 5-deoxyadenosyl-cobalamin. Deficiency of TC results in an elevation in methylmalonic acid and homocysteine. Patients usually present with macrocytic anemia, pancytopenia, failure to thrive, gastrointestinal symptoms, and neurological dysfunction...
May 22, 2017: Journal of Pediatric Hematology/oncology
https://www.readbyqxmd.com/read/28535762/gait-initiation-and-termination-strategies-in-patients-with-prader-willi-syndrome
#16
Veronica Cimolin, Nicola Cau, Manuela Galli, Cristina Santovito, Graziano Grugni, Paolo Capodaglio
BACKGROUND: Gait Initiation (GI) is a functional task representing one of the first voluntary destabilizing behaviours observed in the development of a locomotor pattern as the whole body centre of mass transitions from a large to a small base of support. Conversely, Gait Termination (GT) consists in the transition from walking to standing which, in everyday life, is a very common movement. Compared to normal walking, it requires higher control of postural stability. For a safe GT, the forward movement of the body has to be slowed down to achieve a stable upright position...
May 23, 2017: Journal of Neuroengineering and Rehabilitation
https://www.readbyqxmd.com/read/28533617/estimated-lower-speed-boundary-at-which-the-walk-ratio-constancy-is-broken-in-healthy-adults
#17
Rumi Murakami, Yohei Otaka
[Purpose] The ratio of step length to cadence (walk ratio) is invariant over a wide range of speeds. However, no studies have investigated details of the change in the walk ratio at slow speeds. It is necessary to explore how walking behavior changes at a low speed to understand the slow walking observed in various conditions such as aging and pathological conditions. In this study, changes in the walk ratio at slow speeds were investigated, and a lower boundary was estimated at which the walk ratio constancy is broken...
April 2017: Journal of Physical Therapy Science
https://www.readbyqxmd.com/read/28530503/comparison-of-self-selected-walking-speeds-and-walking-speed-variability-when-data-are-collected-during-repeated-discrete-trials-and-during-continuous-walking
#18
Marcus J Brown, Laura A Hutchinson, Michael J Rainbow, Kevin J Deluzio, Alan R De Asha
A typical gait analysis data collection consists of a series of discrete trials, where a participant initiates gait, walks through a motion capture volume, and then terminates gait. This is not a normal 'everyday' gait pattern, yet measurements are considered representative of normal walking. However, walking speed, a global descriptor of gait quality that can affect joint kinematics and kinetics, may be different during discrete trials, compared to continuous walking. Therefore, the purpose of this study was to investigate the effect of continuous walking versus discrete trials on walking speed and walking speed variability...
May 22, 2017: Journal of Applied Biomechanics
https://www.readbyqxmd.com/read/28525675/acellular-dermal-matrix-and-heel-reconstruction-a-new-prospective
#19
Alessandro Scalise, Matteo Torresetti, Federica Verdini, Marianna Capecci, Elisa Andrenelli, Alessandro Mengarelli, Maria Gabriella Ceravolo, Sandro Fioretti, Giovanni Di Benedetto
BACKGROUND: Heel reconstruction represents a challenge for all plastic surgeons due to the anatomical and functional features of this weight-bearing area. In the last decade a combined use of acellular dermal matrices and skin grafts has been proposed as a reliable and less invasive alternative for complex wound management; nevertheless only a few cases have been reported in the literature. METHODS: We describe the long-term outcome of 2 cases of severe degloving trauma of the plantar region with massive soft tissue defects of the foot, that underwent surgical reconstruction with artificial dermis and skin grafts...
May 19, 2017: Journal of Applied Biomaterials & Functional Materials
https://www.readbyqxmd.com/read/28523357/lesion-location-associated-with-balance-recovery-and-gait-velocity-change-after-rehabilitation-in-stroke-patients
#20
Hyun Im Moon, Hyo Jeong Lee, Seo Yeon Yoon
PURPOSE: Impaired gait function after stroke contributes strongly to overall patient disability. However, the response to rehabilitation varies between individuals. The aims of this study were to identify predictors of gait velocity change and to elucidate lesion location associated with change of balance and gait function. METHODS: We reviewed 102 stroke patients. The patients were divided into two groups according to gait ability post-rehabilitation, and we analyzed differences in their characteristics, such as demographic information, lesion factors, and initial balance function...
May 18, 2017: Neuroradiology
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