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gait initiation

Ignacio Jusué-Torres, Lee H Jeon, Eric W Sankey, Jennifer Lu, Tito Vivas-Buitrago, Joshua A Crawford, Mikhail V Pletnikov, Jiadi Xu, Ari Blitz, Daniel A Herzka, Barbara Crain, Alicia Hulbert, Hugo Guerrero-Cazares, Oscar Gonzalez-Perez, James P McAllister, Alfredo Quiñones-Hinojosa, Daniele Rigamonti
BACKGROUND: The pathogenesis of adult chronic hydrocephalus is not fully understood, and the temporal relationship between development of the radiological changes and neurological deterioration is unknown. OBJECTIVE: To clarify the progression of radiological-histological changes and subsequent clinical manifestations of adult chronic hydrocephalus. METHODS: Kaolin was injected bilaterally into the subarachnoid space overlying the cranial convexities in 20 adult rats...
November 2016: Neurosurgery
Zhenlong Liu, Xiaoqing Hu, Zhentao Man, Jiying Zhang, Yanfang Jiang, Yingfang Ao
Though many surgical animal models have been used to induce osteoarthritis (OA) of the knee joint, they always open the capsule of the joint. Any surgical procedures that incises the capsule may cause inflammation, pain, and possibly altered gait. One common disadvantage of these surgically induced animal models is that they may affect the initial structures and synovial fluid in joint. These animal models may not be suitable for research into synovial fluid changes during early OA. This study aimed to create an animal model of early OA by resecting the medial collateral ligament (MCL) outside of the capsule...
October 19, 2016: Scientific Reports
Robert P Lamberts, Marlette Burger, Jacques du Toit, Nelleke G Langerak
BACKGROUND: Three-dimensional gait analysis (3DGA) is commonly used to assess the effect of orthopedic single-event multilevel surgery (SEMLS) in children with spastic cerebral palsy (CP). PURPOSE: The purpose of this systematic review is to provide an overview of different orthopedic SEMLS interventions and their effects on 3DGA parameters in children with spastic CP. METHODS: A comprehensive literature search within six databases revealed 648 records, from which 89 articles were selected for the full-text review and 24 articles (50 studies) included for systematic review...
2016: PloS One
Qu Tian, Yang An, Susan M Resnick, Stephanie Studenski
BACKGROUND: most older individuals who experience mobility decline, also show cognitive decline, but whether cognitive decline precedes or follows mobility limitation is not well understood. OBJECTIVE: examine the temporal sequence of mobility and cognition among initially unimpaired older adults. METHODS: mobility and cognition were assessed every 2 years for 6 years in 412 participants aged ≥60 with initially unimpaired cognition and gait speed...
October 15, 2016: Age and Ageing
Nima Toosizadeh, Homayoon Harati, Tzu-Chuan Yen, Cindy Fastje, Jane Mohler, Bijan Najafi, Michael Dohm
BACKGROUND: This study examined short- and long-term improvements in motor performance, quantified using wearable sensors, in response to facet spine injection in degenerative facet osteoarthropathy patients. METHODS: Adults with confirmed degenerative facet osteoarthropathy were recruited and were treated with medial or intermediate branch block injection. Self-report pain, health condition, and disability (Oswestry), as well as objective motor performance measures (gait, balance, and timed-up-and-go) were obtained in five sessions: pre-surgery (baseline), immediately after the injection, one-month, three-month, and 12-month follow-ups...
October 11, 2016: Clinical Biomechanics
Jose M Vilar, Belen Cuervo, Monica Rubio, Joaquín Sopena, Juan M Domínguez, Angelo Santana, Jose M Carrillo
BACKGROUND: Subjective pain assessment scales have been widely used for assessing lameness in response to pain, but the accuracy of these scales has been questioned. To assess scale accuracy, 10 lame, presa Canario dogs with osteoarthritis (OA) associated with bilateral hip dysplasia were first treated with mesenchymal stem cells. Then, potential lameness improvement was analyzed using two pain scales (Bioarth and visual analog scale). These data were compared with similar data collected using a force platform with the same animals during a period of 6 months after treatment...
October 7, 2016: BMC Veterinary Research
Yong-Hyun Hwang, Hee-Chun Lee, Jae-Hoon Lee
OBJECTIVE: To examine the technical feasibility of percutaneous endoscopic pediculectomy using a lateral approach and to evaluate its use for decompression and examination of the thoracic and lumbar spinal canals in small dogs. STUDY DESIGN: Experimental study. ANIMALS: Clinically normal adult dogs (n=10). METHODS: After optimizing the technique in cadavers, percutaneous endoscopic pediculectomy was performed using a lateral approach to the thoracic (T12) or lumbar (L2) vertebrae in 5 dogs each...
October 6, 2016: Veterinary Surgery: VS
Jack DiGiovanna, Nadia Dominici, Lucia Friedli, Jacopo Rigosa, Simone Duis, Julie Kreider, Janine Beauparlant, Rubia van den Brand, Marco Schieppati, Silvestro Micera, Grégoire Courtine
: Contrary to cats and primates, cortical contribution to hindlimb locomotor movements is not critical in rats. However, the importance of the motor cortex to regain locomotion after neurological disorders in rats suggests that cortical engagement in hindlimb motor control may depend on the behavioral context. To investigate this possibility, we recorded whole-body kinematics, muscle synergies, and hindlimb motor cortex modulation in freely moving rats performing a range of natural locomotor procedures...
October 5, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Frank E Fish
Re-invasion of the aquatic environment by terrestrial vertebrates resulted in the evolution of species expressing a suite of adaptations for high-performance swimming. Examination of swimming by secondarily aquatic vertebrates provides opportunities to understand potential selection pressures and mechanical constraints, which may have directed the evolution of these aquatic species. Mammals and birds realigned the body and limbs for cursorial movements and flight, respectively, from the primitive tetrapod configuration...
October 3, 2016: Integrative and Comparative Biology
Danilovich Margaret
BACKGROUND/OBJECTIVES: To test the effects of Strong for Life (SFL) on the physical performance and self-rated health of older adults receiving Home and Community-Based Services (HCBS). DESIGN: Randomized, two-group trial with pre-post measures. SETTING: In-home exercise program. PARTICIPANTS: Clients aged 65-95 (n=42) and their Home Care Aide (HCA) (n=32) were randomly assigned to a usual care and SFL intervention or usual care control group...
2016: Aging Soc
Simona Ferrante, Noelia Chia Bejarano, Emilia Ambrosini, Antonio Nardone, Anna M Turcato, Marco Monticone, Giancarlo Ferrigno, Alessandra Pedrocchi
It has been largely suggested in neuroscience literature that to generate a vast variety of movements, the Central Nervous System (CNS) recruits a reduced set of coordinated patterns of muscle activities, defined as muscle synergies. Recent neurophysiological studies have recommended the analysis of muscle synergies to finely assess the patient's impairment, to design personalized interventions based on the specific nature of the impairment, and to evaluate the treatment outcomes. In this scope, the aim of this study was to design a personalized multi-channel functional electrical stimulation (FES) controller for gait training, integrating three novel aspects: (1) the FES strategy was based on healthy muscle synergies in order to mimic the neural solutions adopted by the CNS to generate locomotion; (2) the FES strategy was personalized according to an initial locomotion assessment of the patient and was designed to specifically activate the impaired biomechanical functions; (3) the FES strategy was mapped accurately on the altered gait kinematics providing a maximal synchronization between patient's volitional gait and stimulation patterns...
2016: Frontiers in Neuroscience
Masataka Fukuoka, Ichiro Kuki, Hisashi Kawawaki, Kiyohiro Kim, Yuka Hattori, Hitomi Tsuji, Asako Horino, Megumi Nukui, Shin Okazaki
An 11-year-old boy presented with progressive leg hypesthesia but no history of trauma. Dysuria and constipation appeared subsequent to gait difficulty. He was admitted 8days after onset. Spinal magnetic resonance imaging (MRI) revealed longitudinal hyperintensity with cord swelling and hypointensity on T2-weighted images, suggesting severe inflammation and microbleeding change, respectively. Gadolinium contrast-enhanced MRI demonstrated mild enhancement in the lesions. Platelet count and coagulation findings were normal, and cerebrospinal fluid analysis showed no pleocytosis...
September 26, 2016: Brain & Development
Gareth D Jones, Darren C James, Michael Thacker, David A Green
Individuals with sensorimotor pathology e.g., stroke have difficulty executing the common task of rising from sitting and initiating gait (sit-to-walk: STW). Thus, in clinical rehabilitation separation of sit-to-stand and gait initiation - termed sit-to-stand-and-walk (STSW) - is usual. However, a standardized STSW protocol with a clearly defined analytical approach suitable for pathological assessment has yet to be defined. Hence, a goal-orientated protocol is defined that is suitable for healthy and compromised individuals by requiring the rising phase to be initiated from 120% knee height with a wide base of support independent of lead limb...
2016: Journal of Visualized Experiments: JoVE
Tara Nazareth, Howard S Friedman, Prakash Navaratnam, Denise A Herriott, John J Ko, Peri Barr, Rahul Sasane
BACKGROUND: In the US, the approved multiple sclerosis (MS) oral disease-modifying therapies (ODMTs) are fingolimod (FTY), teriflunomide (TFN), and dimethyl fumarate (DMF). FTY and TFN are recommended with once-daily doses with no up-titration, whereas DMF treatment is recommended twice-daily (BID) and is initiated with a 7-day starter dose of 120 mg BID before up-titration to the maintenance dose of 240 mg BID. Limited information exists regarding real-world ODMT prescribing patterns to aid physician/patient decision-making...
September 29, 2016: BMC Neurology
Mona Diegelmann, Hans-Werner Wahl, Oliver K Schilling, Carl-Philipp Jansen, Katrin Classen, Klaus Hauer
BACKGROUND: Depressive symptoms are highly prevalent in nursing home (NH) residents. The relationship between depressive symptoms and everyday competence in terms of basic (BaCo) and expanded everyday competence (ExCo; see Baltes et al., 2001) in the NH setting is, however, not clear. Applying Lewinsohn's depression model, we examined how residents' BaCo and ExCo relate to their depressive symptoms. Furthermore, we investigated the mediating role of perceived control. METHODS: Cross-sectional data from 196 residents (M age = 83...
September 29, 2016: International Psychogeriatrics
Peter Gross, Thomas Pusl
Hyponatremia is a common electrolyte disorder that arises from disturbances in water metabolism. In cases of acute advanced hyponatremia, serious symptoms are predominant, while chronic mild hyponatremia causes minor symptoms such as slowness, depression or unsteadiness of gait. Any therapy of hyponatremia depends on the severity of its symptoms and on its specific etiology and diagnosis. Concerning the differential diagnosis of the type of hyponatremia, it is initially helpful to distinguish between euvolemic, hypervolemic and hypovolemic forms of hyponatremia...
October 2016: Deutsche Medizinische Wochenschrift
Katell Denis, Florian Bidet, Jerome Egault, Arnaud Gautier, Pauline Coignard, Katel Rinfray, Marie-Lise Peuziat, Jean-Paul Departe, Jean-Luc Le-Guiet, Nolwenn Morisset, Nathalie Pichot, Isabelle Bonan
OBJECTIVE: Robotic systems allow to initiate and facilitate the implementation of a movement executed by the patient. The objective was to test the interest of an innovative gait robot. MATERIALS/PATIENTS AND METHODS: Eighteen patients 53.6 (±11.1) years aged, with a functional ambulation category (FAC) 0 to 5, followed 3 sessions of 45min/week with the mobile robot with body weight support during 4 weeks while maintaining conventional physiotherapy sessions. This evolutionary robot provides, in stationary mode balance training safely through suspension, and in mobile mode gait training according to various trajectories...
September 2016: Annals of Physical and Rehabilitation Medicine
Céline Coffineau, Annabelle Couillandre, Jean Chapus, Nicolas Lampire
OBJECTIVE: During rehabilitation of hemiparetic patients, physiotherapists face a discrepancy between motor skills during analytical exercises and functional abilities observed during gait. A muscle recruitment difference in the two situations could explain this gap. Among pathologic motricity manifestations observed in hemiparetic patients (Gracies 2005), exist the spastic co contraction phenomenon that presently concerned our work. Indeed, the main objective of this study was to compare co-contractions in hemiparetic subjects between an analytical exercise modality and a functional exercise modality, i...
September 2016: Annals of Physical and Rehabilitation Medicine
Jean-Sébastien Bourseul, Mael Lintanf, Philippe Saliou, Sylvain Brochard, Christelle Pons
OBJECTIVE: Different ankle-foot orthoses (AFO) are often prescribed in children with cerebral palsy (PC) although their efficiency on gait remains unclear. PURPOSE: (1) To determine the effect of AFOs on gait in children with CP and (2) to evaluate the effect of each types of AFO. MATERIAL AND METHODS: Studies in English with control condition (barefoot or shoes) assessing effect of AFO about children with CP gait were search on the Pubmed, CINAHL+, Web of Science, Cochrane Library databases...
September 2016: Annals of Physical and Rehabilitation Medicine
Mehri Christopher, Yoshimasa Sagawa, Céline Bernard, Thierry Moulin, Eloi Magnin, Pierre Decavel
OBJECTIVE: Fampridine is used as a symptomatic treatment in patients with multiple sclerosis (PwMS) gait disorders. Some clinical trials reported a positive effect on cognitive function especially on information-processing speed (IPS) or on fatigue. The aim of our clinical trial was to evaluate the effect of fampridine on IPS. MATERIAL/PATIENTS AND METHODS: 60 PwMS with an EDSS score between 4 and 7 were included in a prospective monocentric open label trial. Two identical measures were conducted a week apart before initiating treatment in order to take into account the test-retest effect...
September 2016: Annals of Physical and Rehabilitation Medicine
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