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https://www.readbyqxmd.com/read/28428760/the-variation-tendency-of-polyamines-forms-and-components-of-polyamine-metabolism-in-zoysiagrass-zoysia-japonica-steud-to-salt-stress-with-exogenous-spermidine-application
#1
Shucheng Li, Linlin Cui, Yujuan Zhang, Yunwen Wang, Peisheng Mao
To understand dynamic changes in polyamines (PAs) forms and components of polyamine metabolism in zoysiagrass (Zoysia japonica Steud.) response to salt stress with exogenous spermidine (Spd) application, two Chinese zoysia cultivars, z081 and z057, were exposed to sodium chloride stress for 2, 4, 6, and 8 days. The z057 cultivar possesses higher salinity tolerance than the z081 cultivar. Salt stress decreased the zoysiagrass fresh weight (FW) and increased free Spd and spermine (Spm) levels and soluble and insoluble putrescine (Put), Spd and Spm levels in both cultivars...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28420983/increased-oxidative-stress-markers-in-cerebrospinal-fluid-from-healthy-subjects-with-parkinson-s-disease-associated-lrrk2-gene-mutations
#2
David A Loeffler, Andrea C Klaver, Mary P Coffey, Jan O Aasly, Peter A LeWitt
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of inherited Parkinson's disease (PD). The most common PD-associated LRRK2 mutation, G2019S, induces increased production of reactive oxygen species in vitro. We therefore hypothesized that individuals with PD-associated LRRK2 mutations might have increased concentrations of oxidative stress markers and/or decreased total antioxidant capacity (TAC) in their cerebrospinal fluid (CSF). We measured two oxidative stress markers, namely 8-hydroxy-2'-deoxyguanosine (8-OHdG) and 8-isoprostane (8-ISO), and TAC in CSF from LRRK2 mutation-bearing PD patients (LRRK2 PD = 19), sporadic PD patients (sPD = 31), and healthy control subjects with or without these mutations (LRRK2 CTL = 30, CTL = 27)...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28420361/health-care-availability-quality-and-unmet-need-a-comparison-of-transgender-and-cisgender-residents-of-ontario-canada
#3
Rachel Giblon, Greta R Bauer
BACKGROUND: Evidence suggests that transgender (trans) individuals in Canada are a medically underserved population; barriers range from lack of provider knowledge on trans issues to refusal of care. This paper provides the first formal estimation of health care inequalities between trans and cisgender individuals in Ontario, Canada. METHODS: Weighted statistics from the Ontario-wide Trans PULSE Project (n = 433) were compared with age-standardized Ontario data from the Canadian Community Health Survey (n = 39,980) to produce standardized prevalence differences (SPDs)...
April 18, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28418654/a-robust-and-accurate-tight-binding-quantum-chemical-method-for-structures-vibrational-frequencies-and-noncovalent-interactions-of-large-molecular-systems-parametrized-for-all-spd-block-elements-z-1-86
#4
Stefan Grimme, Christoph Bannwarth, Philip Shushkov
We propose a novel, special purpose semiempirical tight binding (TB) method for the calculation of structures, vibrational frequencies, and noncovalent interactions of large molecular systems with 1000 or more atoms. The functional form of the method is related to the self-consistent density functional TB scheme and mostly avoids element-pair-specific parameters. The parametrization covers all spd-block elements and the lanthanides up to Z = 86 using reference data at the hybrid density functional theory level...
April 24, 2017: Journal of Chemical Theory and Computation
https://www.readbyqxmd.com/read/28412896/disparities-in-health-care-utilization-and-functional-limitations-among-adults-with-serious-psychological-distress-2006-2014
#5
Judith Weissman, David Russell, Melanie Jay, Jeannette M Beasley, Dolores Malaspina, Cheryl Pegus
OBJECTIVE: This study compared health care access, utilization, and functional indicators among adults with and without serious psychological distress (SPD) in the years surrounding implementation of the Patient Portable and Affordable Care Act (ACA). METHODS: Adults ages 18 to 64 from the 2006-2014 National Health Interview Survey (N=207, 853) were examined on 11 access, utilization, and functional indicators: health insurance coverage (health coverage), insufficient money for medications, delay in health care (delay in care), insufficient money for health care, visiting a doctor ten or more times in the past 12 months, change in place of health care, change in place of health care due to insurance, limitations in ability to work, limitations in activities of daily living (ADLs), insufficient money for mental health care, and having seen a mental health care provider...
April 17, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/28411424/drug-use-among-transgender-people-in-ontario-canada-disparities-and-associations-with-social-exclusion
#6
Ayden I Scheim, Greta R Bauer, Mostafa Shokoohi
INTRODUCTION: We identified the prevalence and correlates of past-year illicit drug use among transgender people in Ontario, Canada, and disparities with the age-standardized non-transgender population. METHODS: Data on transgender persons aged 16+ (n=406) were obtained from Trans PULSE, a respondent-driven sampling (RDS) survey (2009-2010). Overall and sex-specific estimates of past-year drug use (cocaine and amphetamines, based on data availability) in the reference population were obtained from Ontario residents aged 16+ (n=39, 980) in the Canadian Community Health Survey (2009-2010), and standardized to the overall and gender-specific transgender age distributions...
March 31, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28403468/serious-psychological-distress-and-smoking-during-pregnancy-in-the-united-states-2008-2014
#7
Renee D Goodwin, Keely Cheslack-Postava, Deborah B Nelson, Philip H Smith, Deborah S Hasin, Teresa Janevic, Nina Bakoyiannis, Melanie M Wall
Introduction: The current study examined the relationship between acute (past 30 day) and recent (past year but not past 30 day) serious psychological distress (SPD) and smoking during pregnancy among women in the United States overall, stratified by demographic characteristics, and described the change in the prevalence of prenatal smoking among women with and without SPD, from 2008 to 2014. Methods: Data were drawn from the National Survey on Drug Use and Health (NSDUH), an annual cross-sectional study of US persons aged 12 and over...
May 1, 2017: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/28397579/secondary-paroxysmal-dyskinesia-in-multiple-sclerosis-clinical-radiological-features-and-treatment-case-report-of-seven-patients
#8
Ethel Ciampi, Reinaldo Uribe-San-Martín, Jaime Godoy-Santín, Juan Pablo Cruz, Claudia Cárcamo-Rodríguez, Carlos Juri
Secondary paroxysmal dyskinesias (SPDs) are short, episodic, and recurrent movement disorders, classically related to multiple sclerosis (MS). Carbamazepine is effective, but with risk of adverse reactions. We identified 7 patients with SPD among 457 MS patients (1.53%). SPD occurred in face ( n = 1), leg ( n = 2), or arm +leg ( n = 4) several times during the day. Magnetic resonance imaging (MRI) showed new or enhancing lesions in thalamus ( n = 1), mesencephalic tegmentum ( n = 1), and cerebellar peduncles ( n = 5)...
April 1, 2017: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/28396725/three-dimensional-radiation-dosimetry-using-polymer-gel-and-solid-radiochromic-polymer-from-basics-to-clinical-applications
#9
REVIEW
Yoichi Watanabe, Leighton Warmington, N Gopishankar
Accurate dose measurement tools are needed to evaluate the radiation dose delivered to patients by using modern and sophisticated radiation therapy techniques. However, the adequate tools which enable us to directly measure the dose distributions in three-dimensional (3D) space are not commonly available. One such 3D dose measurement device is the polymer-based dosimeter, which changes the material property in response to radiation. These are available in the gel form as polymer gel dosimeter (PGD) and ferrous gel dosimeter (FGD) and in the solid form as solid plastic dosimeter (SPD)...
March 28, 2017: World Journal of Radiology
https://www.readbyqxmd.com/read/28383077/involvement-of-ethylene-and-polyamines-biosynthesis-and-abdominal-phloem-tissues-characters-of-wheat-caryopsis-during-grain-filling-under-stress-conditions
#10
Weibing Yang, Yanxia Li, Yanping Yin, Zhilie Qin, Mengjing Zheng, Jin Chen, Yongli Luo, Dangwei Pang, Wenwen Jiang, Yong Li, Zhenlin Wang
Severe water deficit (SD) severely limited the photo-assimilate supply during the grain-filling stages. Although the ethylene and polyamines (PAs) have been identified as important signaling molecules involved in stress tolerance, it is yet unclear how 1-Aminocylopropane-1-carboxylic acid (ACC) and PA biosynthesis involving wheat abdominal phloem characters mitigate SD-induced filling inhibition. The results obtained indicated that the SD down-regulated the TaSUT1 expression and decreased the activities of sucrose synthase (SuSase, EC2...
April 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28381926/subperiosteal-drainage-versus-subdural-drainage-in-the-management-of-chronic-subdural-hematoma-a-comparative-study
#11
Adrian Ng Wei Chih, Albert Wong Sii Hieng, Noor Azman A Rahman, Jafri Malin Abdullah
INTRODUCTION: Symptomatic chronic subdural hematomas (CSDH) remain one of the most frequent diagnoses in current neurosurgical practice. Burr-hole craniostomy with irrigation and placement of close-system drainage is the current recommended surgery for symptomatic CSDH. The aim of this study is to perform a direct comparison between two surgical techniques in the treatment of symptomatic CSDH, which have been proven in previous studies to be efficient. Our main objective was to compare the efficacy of placement of a subperiosteal drain (SPD) and a subdural drain (SDD) following single burr-hole craniostomy and irrigation, and to demonstrate any significant differences in terms of overall surgical complications, functional outcome at three months and mortality rate...
March 2017: Malaysian Journal of Medical Sciences: MJMS
https://www.readbyqxmd.com/read/28380008/a-pilot-study-to-determine-the-feasibility-of-enhancing-cognitive-abilities-in-children-with-sensory-processing-dysfunction
#12
Joaquin A Anguera, Anne N Brandes-Aitken, Ashley D Antovich, Camarin E Rolle, Shivani S Desai, Elysa J Marco
Children with Sensory Processing Dysfunction (SPD) experience incoming information in atypical, distracting ways. Qualitative challenges with attention have been reported in these children, but such difficulties have not been quantified using either behavioral or functional neuroimaging methods. Furthermore, the efficacy of evidence-based cognitive control interventions aimed at enhancing attention in this group has not been tested. Here we present work aimed at characterizing and enhancing attentional abilities for children with SPD...
2017: PloS One
https://www.readbyqxmd.com/read/28371657/brain-derived-neurotrophic-factor-val66met-genotype-modulates-amygdala-habituation
#13
M Mercedes Perez-Rodriguez, Antonia S New, Kim E Goldstein, Daniel Rosell, Qiaoping Yuan, Zhifeng Zhou, Colin Hodgkinson, David Goldman, Larry J Siever, Erin A Hazlett
A deficit in amygdala habituation to repeated emotional stimuli may be an endophenotype of disorders characterized by emotion dysregulation, such as borderline personality disorder (BPD). Amygdala reactivity to emotional stimuli is genetically modulated by brain-derived neurotrophic factor (BDNF) variants. Whether amygdala habituation itself is also modulated by BDNF genotypes remains unknown. We used imaging-genetics to examine the effect of BDNF Val66Met genotypes on amygdala habituation to repeated emotional stimuli...
March 24, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28365205/articular-ultrasound-in-asymptomatic-volunteers-identification-of-the-worst-measures-of-synovial-hypertrophy-synovial-blood-flow-and-joint-damage-among-small-medium-%C3%A2-and-large-sized-joints
#14
Flávia Soares Machado, Jamil Natour, Rogerio Diniz Takahashi, Rita N V Furtado
Articular ultrasound of 6500 joint recesses was performed for the purpose of identifying which joint had the highest measurements among small-sized (SSJ), medium-sized (MSJ) and large-sized (LSJ) joints. Quantitative measurements of synovial hypertrophy (QSR) and semiquantitative measurements of synovial hypertrophy (SSH), power Doppler (SPD) and bone erosion (SBE) (score: 0-3) were made. Higher measurements (p < 0.01) of QSR were obtained in the second metatarsophalangeal joint (MTP), talonavicular joint, and hip...
March 29, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28363182/sulfate-radical-based-oxidation-of-antibiotics-sulfamethazine-sulfapyridine-sulfadiazine-sulfadimethoxine-and-sulfachloropyridazine-formation-of-so2-extrusion-products-and-effects-of-natural-organic-matter
#15
Yuefei Ji, Yuanyuan Shi, Lu Wang, Junhe Lu, Corinne Ferronato, Jean-Marc Chovelon
The widespread occurrence of sulfonamide antibiotics in the environment has raised great concerns about their potential to proliferate antibacterial resistance. Sulfate radical (SO4(•-)) based advanced oxidation processes (SR-AOPs) are promising in-situ chemical oxidation (ISCO) technologies for remediation of soil and groundwater contaminated by antibiotics. The present study reported that thermally activated persulfate oxidation of sulfonamides (SAs) bearing six-membered heterocyclic rings, e.g., sulfamethazine (SMZ), sulfapyridine (SPD), sulfadiazine (SDZ), sulfadimethoxine (SDM), and sulfachloropyridazine (SCP), all produced SO2 extrusion products (SEPs), a phenomenon that is of potential importance, but not systematically studied...
March 28, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28355209/coefficients-of-variation-of-ground-reaction-force-measurement-in-cats
#16
Eva Schnabl-Feichter, Alexander Tichy, Barbara Bockstahler
Gait analysis has been extensively performed in dogs and horses; however, very little is known about feline biomechanics. It was, therefore, the aim of this study to determine the coefficient of variation (CV) among three ground reaction force (GRF) measurements taken for 15 client-owned European shorthaired cats without a training period and a short acclimatisation time. Gait was measured as each cat walked across a pressure-sensitive walkway, and measurements were made three times over a multi-week period (range: 2 to 17 weeks)...
2017: PloS One
https://www.readbyqxmd.com/read/28349165/programmed-death-ligand-1-and-its-soluble-form-are-highly-expressed-in-nasal-natural-killer-t-cell-lymphoma-a-potential-rationale-for-immunotherapy
#17
Toshihiro Nagato, Takayuki Ohkuri, Kenzo Ohara, Yui Hirata, Kan Kishibe, Yuki Komabayashi, Seigo Ueda, Miki Takahara, Takumi Kumai, Kei Ishibashi, Akemi Kosaka, Naoko Aoki, Kensuke Oikawa, Yuji Uno, Naoko Akiyama, Masatoshi Sado, Hidehiro Takei, Esteban Celis, Yasuaki Harabuchi, Hiroya Kobayashi
Nasal natural killer/T-cell lymphoma (NNKTL) is an aggressive neoplasm with poor therapeutic responses and prognosis. The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) pathway plays an important role in immune evasion of tumor cells through T-cell exhaustion. The aim of the present study was to examine the expression of PD-L1 and PD-1 molecules in NNKTL. We detected the expression of PD-L1 in biopsy samples from all of the NNKTL patients studied. PD-L1 was found on both malignant cells and tumor-infiltrating macrophages, while PD-1-positive mononuclear cells infiltrated the tumor tissues in 36% of patients...
March 27, 2017: Cancer Immunology, Immunotherapy: CII
https://www.readbyqxmd.com/read/28348831/methionine-mediated-gene-expression-and-characterization-of-the-cmhr-regulon-in-streptococcus-pneumoniae
#18
Muhammad Afzal, Sulman Shafeeq, Oscar P Kuipers
This study investigated the transcriptomic response of Streptococcus pneumoniae D39 to methionine. Transcriptome comparison of the S. pneumoniae D39 wild-type grown in chemically defined medium with 0-10 mM methionine revealed the elevated expression of various genes/operons involved in methionine synthesis and transport (fhs, folD, gshT, metA, metB-csd, metEF, metQ, tcyB, spd-0150, spd-0431 and spd-0618). Furthermore, β-galactosidase assays and quantitative RT-PCR studies demonstrated that the transcriptional regulator, CmhR (SPD-0588), acts as a transcriptional activator of the fhs, folD, metB-csd, metEF, metQ and spd-0431 genes...
October 2016: Microbial Genomics
https://www.readbyqxmd.com/read/28347257/antipsychotic-treatment-of-schizotypy-and-schizotypal-personality-disorder-a-systematic-review
#19
Klaus Damgaard Jakobsen, Eva Skyum, Nasseh Hashemi, Ole Schjerning, Anders Fink-Jensen, Jimmi Nielsen
Schizotypal personality disorder (SPD) is characterised by thought disorders, experiences of illusions, obsessive ruminations, bizarre or eccentric behaviour, cognitive problems and deficits in social functioning - symptoms that SPD shares with schizophrenia. Efforts have been undertaken to investigate the relationship between these conditions regarding genetics, pathophysiology, and phenomenology. However, treatment of SPD with antipsychotics has received less scientific attention. Embase and PubMed databases were searched using all known generic names of antipsychotics as search terms in combination with the following diagnostic terms: latent schizophrenia, schizotypal disorder, latent type schizophrenia, or SPD...
April 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28340530/effect-of-severe-plastic-deformation-on-structure-and-properties-of-al-sc-ta-and-al-sc-ti-alloys
#20
Alla Berezina, Tetiana Monastyrska, Olexandr Davydenko, Oleh Molebny, Sergey Polishchuk
The comparative analysis of the effect of monotonous and non-monotonous severe plastic deformations (SPD) on the structure and properties of aluminum alloys has been carried out. Conventional hydrostatic extrusion (HE) with a constant deformation direction and equal-channel angular hydroextrusion (ECAH) with an abrupt change in the deformation direction were chosen for the cases of monotonous and non-monotonous SPD, respectively. Model cast hypoeutectic Al-0.3%Sc alloys and hypereutectic Al-0.6%Sc alloys with Ta and Ti additives were chosen for studying...
December 2017: Nanoscale Research Letters
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