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https://www.readbyqxmd.com/read/29471379/do-women-and-men-have-the-same-patterns-of-multiple-occupational-carcinogenic-exposures-results-from-a-cohort-of-cancer-patients
#1
Mélanie Bertin, Annie Thébaud-Mony, Emilie Counil
Complex exposure situations are frequent at the workplace, but few studies have characterized multiple occupational carcinogenic exposures (MOCE) and their gendered differences across jobs' characteristics. We assessed MOCE separately in male and female jobs and identified patterns of MOCE at job level. Participants (834 men and 183 women) were cancer patients recruited between March 2002 and December 2010 in the ongoing SCOP93 cohort study, Seine-Saint-Denis department, France. Job histories were collected through personal interviews, and carcinogenic exposures were assessed by a multidisciplinary expert committee using a list of 53 carcinogens...
February 17, 2018: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29470991/modeling-factors-that-regulate-cell-cooperativity-in-the-zebrafish-posterior-lateral-line-primordium
#2
Leif Zinn-Björkman, Frederick R Adler
Collective cell migration is an integral part of organismal development. We consider migration of the zebrafish primordium during development of the posterior lateral line, a sensory system that detects water movement patterns. Experiments have shown that the chemokine ligand CXCL12a and its receptors CXCR4b and CXCR7b are key players for driving migration of the primordium, while FGF signaling helps maintain cohesion. In this work, we formulate a mathematical model of a laser ablated primordium separated into two smaller cell collectives: a leading collective that responds to local CXCL12a levels and a trailing collective that migrates up a local FGF gradient...
February 19, 2018: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/29470959/differential-effects-of-serotonin-reuptake-inhibitors-fluoxetine-and-escitalopram-on-bone-markers-and-microarchitecture-in-wistar-rats
#3
Manoj Kumar, Ravisha Wadhwa, Priyanka Kothari, Ritu Trivedi, Divya Vohora
Evidence from several studies indicates that the long-term treatment of selective serotonin reuptake inhibitors (SSRIs) is associated with a decrease in bone mass and increase the risk of fractures. The present work evaluated and compared the effect of treatment with two SSRIs viz. fluoxetine and escitalopram on bone biomarkers (P1NP and βCTX) in male Wistar rats. In addition, the effect of these drugs on bone microarchitecture of lumbar and tibia bones was carried out. Fluoxetine (8.2mg/kg) treatment for 40 days significantly reduced (P< 0...
February 19, 2018: European Journal of Pharmacology
https://www.readbyqxmd.com/read/29470649/structural-arrangement-of-the-intrinsic-muscles-of-the-tongue-and-their-relationships-with-the-extrinsic-muscles
#4
Yujiro Sakamoto
The tongue is a dense muscular organ, in which the muscles are arranged in a confusing pattern. The intrinsic muscles were gross anatomically investigated in 25 cadavers to clarify their configuration. The superior longitudinal muscle (SLm) ran beneath the dorsal mucosa and was divided into bundles by the other muscles passing through it to the dorsum. The external bundle of the styloglossus, with the palatoglossus, coursed externally to the hyoglossus. Their fibers spread beneath the SLm or attached to the apex and the inferior longitudinal muscle (ILm) ascended from the root and joined them...
February 22, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29470429/belowground-interactions-impact-the-soil-bacterial-community-soil-fertility-and-crop-yield-in-maize-peanut-intercropping-systems
#5
Qisong Li, Jun Chen, Linkun Wu, Xiaomian Luo, Na Li, Yasir Arafat, Sheng Lin, Wenxiong Lin
Intercropping has been widely used to control disease and improve yield in agriculture. In this study, maize and peanut were used for non-separation intercropping (NS), semi-separation intercropping (SS) using a nylon net, and complete separation intercropping (CS) using a plastic sheet. In field experiments, two-year land equivalent ratios (LERs) showed yield advantages due to belowground interactions when using NS and SS patterns as compared to monoculture. In contrast, intercropping without belowground interactions (CS) showed a yield disadvantage...
February 22, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29469966/the-effect-of-skin-surface-topography-and-skin-colouration-cues-on-perception-of-male-facial-age-health-and-attractiveness
#6
Bernhard Fink, Paul J Matts, Christina Brauckmann, Sina Gundlach
OBJECTIVE: Previous studies investigating the effects of skin surface topography and colouration cues on perception of female faces reported a differential weighting for perception of skin topography and colour evenness, where topography was a stronger visual cue for perception of age, whereas skin colour evenness was a stronger visual cue for perception of health. We extend these findings in a study of the effect of skin surface topography and colour evenness cues on perceptions of facial age, health, and attractiveness in males...
February 22, 2018: International Journal of Cosmetic Science
https://www.readbyqxmd.com/read/29469747/multiple-eccrine-spiradenomas-in-a-zosteriform-pattern
#7
Monica Rosales Santillan, Kathrene ATajnert, Michael G Swaby, Michael R Migden, Sirunya Silapunt
Eccrine spiradenoma (ES) typically presents as a solitary tender lesion. Multiple ES is a rare variant of ES and can present in a segmental, linear, blaschkoid, or zosteriform pattern. The etiology of multiple ES is unknown, but several theories have been suggested including a multipotent stem cell origin. We report the case of a 30-year-old woman with multiple painful ES in a zosteriform pattern on the mid-back and abdomen. Skin biopsy of a representative lesion demonstrated a circumscribed tumor nodule encapsulated by a fibrous capsule with diffuse dense basophilic proliferation located in the dermis...
August 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469746/allergic-contact-dermatitis-to-methylisothiazolinone-in-hair-care-products-report-of-a-case
#8
Rachel Gilmore, Girija Shan, Rajani Katta
Eccrine spiradenoma (ES) typically presents as a solitary tender lesion. Multiple ES is a rare variant of ES and can present in a segmental, linear, blaschkoid, or zosteriform pattern. The etiology of multiple ES is unknown, but several theories have been suggested including a multipotent stem cell origin. We report the case of a 30-year-old woman with multiple painful ES in a zosteriform pattern on the mid-back and abdomen. Skin biopsy of a representative lesion demonstrated a circumscribed tumor nodule encapsulated by a fibrous capsule with diffuse dense basophilic proliferation located in the dermis...
August 15, 2017: Dermatology Online Journal
https://www.readbyqxmd.com/read/29469163/a-method-for-characterising-human-intervertebral-disc-glycosaminoglycan-disaccharides-using-liquid-chromatography-mass-spectrometry-with-multiple-reaction-monitoring
#9
X Liu, D Krishnamoorthy, L Lin, P Xue, F Zhang, L Chi, R J Linhardt, J C Iatridis
Intervertebral disc (IVD) degeneration results in the depletion of proteoglycans and glycosaminoglycans (GAGs), which can lead to structural and mechanical loss of IVD function, ingrowth of nociceptive nerve fibres and eventually discogenic pain. Specific GAG types as well as their disaccharide patterns can be predictive of disease and degeneration in several tissues but have not been comprehensively studied within the IVD. A highly sensitive mass spectrometry based technique with multiple reaction monitoring (MRM) was used to provide characterisation of chondroitin sulphate (CS), hyaluronic acid (HA), heparan sulphate (HS) and their disaccharide sulphation patterns across different anatomical regions of human IVDs...
February 22, 2018: European Cells & Materials
https://www.readbyqxmd.com/read/29469009/dairy-consumption-and-inflammatory-profile-a-cross-sectional-population-based-study-s%C3%A3-o-paulo-brazil
#10
Tábata Natal Gadotti, Marina Maintinguer Norde, Marcelo Macedo Rogero, Mauro Fisberg, Regina Mara Fisberg, Erica Oki, Lígia Araújo Martini
OBJECTIVES: The aim of this study was to investigate the association between dairy product consumption and plasma inflammatory biomarkers levels among a representative sample of Brazilian adults from São Paulo City. METHODS: Data were acquired from the Health Survey for São Paulo, a cross-sectional population-based study. All individuals 20 to 59 y of age with complete food consumption information (24-h dietary recall and food frequency questionnaire) and blood sample analysis were included (N = 259)...
October 26, 2017: Nutrition
https://www.readbyqxmd.com/read/29468505/a-cross-cultural-perspective-on-the-relationships-between-emotional-separation-parental-trust-and-identity-in-adolescents
#11
Kazumi Sugimura, Elisabetta Crocetti, Kai Hatano, Goda Kaniušonytė, Shogo Hihara, Rita Žukauskienė
Emotional separation and parental trust in parent-adolescent relationships are important factors for adolescent identity formation. However, prior research findings on emotional separation are inconsistent. This study aimed to conduct a more rigorous examination of the associations of emotional separation and parental trust with identity synthesis, confusion, and consolidation by applying a bi-factor model to identity, using adolescent samples from Lithuania (N = 610; 53.9% female; Mage  = 14.92), Italy (N = 411; 57...
February 21, 2018: Journal of Youth and Adolescence
https://www.readbyqxmd.com/read/29468416/motivational-sensitivity-of-outcome-response-priming-experimental-research-and-theoretical-models
#12
Poppy Watson, Reinout W Wiers, Bernhard Hommel, Sanne de Wit
Outcome-response (O-R) priming is at the core of various associative theories of human intentional action. This is a simple and parsimonious mechanism by which activation of outcome representations (e.g. thinking about the light coming on) leads to activation of the associated motor patterns required to achieve it (e.g. pushing the light switch). In the current manuscript, we review the evidence for such O-R associative links demonstrated by converging (yet until now, separate) strands of research. While there is a wealth of evidence that both the perceptual and motivational properties of an outcome can be encoded in the O-R association and mediate O-R priming, we critically examine the integration of these mechanisms and the conditions under which motivational factors constrain the sensory O-R priming effect...
February 21, 2018: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/29467609/phospho-tau-bar-code-analysis-of-phosphoisotypes-of-tau-and-its-application-to-tauopathy
#13
REVIEW
Taeko Kimura, Govinda Sharma, Koichi Ishiguro, Shin-Ichi Hisanaga
Tau is a microtubule-associated protein which regulates the assembly and stability of microtubules in the axons of neurons. Tau is also a major component of neurofibrillary tangles (NFTs), a pathological hallmark in Alzheimer's disease (AD). A characteristic of AD tau is hyperphosphorylation with more than 40 phosphorylation sites. Aggregates of hyperphosphorylated tau are also found in other neurodegenerative diseases which are collectively called tauopathies. Although a large number of studies have been performed on the phosphorylation of AD tau, it is not known if there is disease-specific phosphorylation among tauopathies...
2018: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29467546/chemiluminescent-detection-of-oligoclonal-immunoglobulins-after-isoelectric-focusing-and-affinity-mediated-immunoblotting
#14
Ondrej Dlouhy, Pavlina Kusnierova, Irena Kurasova, Monika Cisarikova, David Zeman
BACKGROUND AND AIMS: Detection of oligoclonal IgG (o-IgG) in the cerebrospinal fluid (CSF) not found in serum is the principal laboratory test to support a diagnosis of multiple sclerosis. The aim of this study was to compare chemiluminescent and chromogenic detection of oligoclonal immunoglobulins in the cerebrospinal fluid and serum after their separation by means of isoelectric focusing followed by immunoblotting. METHODS: A set of experiments was designed to detect oligoclonal immunoglobulins by means of alkaline phosphatase BCIP/NBT substrate and chemiluminescent peroxidase substrate...
February 21, 2018: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29467480/adenoid-cystic-carcinomas-of-the-salivary-gland-lacrimal-gland-and-breast-are-morphologically-and-genetically-similar-but-have-distinct-microrna-expression-profiles
#15
Simon Andreasen, Qihua Tan, Tina Klitmøller Agander, Petr Steiner, Kristine Bjørndal, Estrid Høgdall, Stine Rosenkilde Larsen, Daiva Erentaite, Caroline Holkmann Olsen, Benedicte Parm Ulhøi, Sarah Linéa von Holstein, Irene Wessel, Steffen Heegaard, Preben Homøe
Adenoid cystic carcinoma is among the most frequent malignancies in the salivary and lacrimal glands and has a grave prognosis characterized by frequent local recurrences, distant metastases, and tumor-related mortality. Conversely, adenoid cystic carcinoma of the breast is a rare type of triple-negative (estrogen and progesterone receptor, HER2) and basal-like carcinoma, which in contrast to other triple-negative and basal-like breast carcinomas has a very favorable prognosis. Irrespective of site, adenoid cystic carcinoma is characterized by gene fusions involving MYB, MYBL1, and NFIB, and the reason for the different clinical outcomes is unknown...
February 21, 2018: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/29467107/associations-between-personal-care-product-use-patterns-and-breast-cancer-risk-among-white-and-black-women-in-the-sister-study
#16
Kyla W Taylor, Melissa A Troester, Amy H Herring, Lawrence S Engel, Hazel B Nichols, Dale P Sandler, Donna D Baird
BACKGROUND: Many personal care products include chemicals that might act as endocrine disruptors and thus increase the risk of breast cancer. OBJECTIVE: We examined the association between usage patterns of beauty, hair, and skin-related personal care products and breast cancer incidence in the Sister Study, a national prospective cohort study (enrollment 2003-2009). METHODS: Non-Hispanic black (4,452) and white women (n=42,453) were examined separately using latent class analysis (LCA) to identify groups of individuals with similar patterns of self-reported product use in three categories (beauty, skin, hair)...
February 21, 2018: Environmental Health Perspectives
https://www.readbyqxmd.com/read/29466716/characterization-and-risk-assessment-of-seasonal-and-weather-dynamics-in-organic-pollutant-mixtures-from-discharge-of-a-separate-sewer-system
#17
Liza-Marie Beckers, Wibke Busch, Martin Krauss, Tobias Schulze, Werner Brack
Sites of wastewater discharge are hotspots for pollution of freshwaters with organic micropollutants and are often associated with adverse effects to aquatic organisms. The assessment, monitoring and managment of these hotspots is challenged by variations in the pollutant mixture composition due to season, weather conditions and random spills. In this study, we unraveled temporal exposure patterns in organic micropollutant mixtures from wastewater discharge and analyzed respective acute and sublethal risks for aquatic organisms...
February 3, 2018: Water Research
https://www.readbyqxmd.com/read/29466677/analysis-of-graft-length-change-patterns-in-medial-patellofemoral-ligament-reconstruction-via-a-fluoroscopic-guidance-method
#18
Takehiko Matsushita, Daisuke Araki, Yuichi Hoshino, Shinya Oka, Kyohei Nishida, Toshikazu Tanaka, Nobuaki Miyaji, Noriyuki Kanzaki, Kazuyuki Ibaraki, Tomoyuki Matsumoto, Masahiro Kurosaka, Ryosuke Kuroda
BACKGROUND: A fluoroscopic guidance method for medial patellofemoral ligament (MPFL) reconstruction has been widely used to determine the anatomic femoral attachment site. PURPOSE: To examine the graft length change patterns in MPFL reconstruction with a fluoroscopic guidance method. STUDY DESIGN: Cross-sectional study; Level of evidence, 3. METHODS: Forty-four knees of 42 patients who underwent MPFL reconstruction for the treatment of recurrent patellar dislocation were examined prospectively...
February 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29465608/muscle-activation-patterns-of-lower-body-musculature-among-three-traditional-lower-body-exercises-in-trained-women
#19
Max R Paquette, Dana K Fuller, Jennifer L Caputo, John M Coons
The deadlift and back and front squats are common multi-joint, lower body resistance exercises that target similar musculature. To our knowledge, muscle activity measured via surface electromyography (EMG) has never been analyzed among these three exercises. Furthermore, most literature examining this topic has included male participants creating a void in the literature for the female population. Knowledge of lower body muscle activation among these three exercises can aid coaches, trainers, and therapists for training and rehabilitative purposes...
February 15, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29464942/flexible-hydrophobic-antifouling-coating-with-oriented-nanotopography-and-non-leaking-capsaicin
#20
Zhiwei Lu, Zhuo Chen, Yi Guo, Yanyun Ju, Yang Liu, Rui Feng, Chuanxi Xiong, Christopher K Ober, Lijie Dong
Incorporating natural product antifoulants (NPAs) into coatings with controlled surface topography is considered a promising way to suppress marine fouling. However, the rapid leakage of NPAs and the relatively complicated process of constructing well-patterned topography remain unresolved problems for practical applications. In this work, capsaicin bonded to CoFe2O4/gelatin magnetic nanoparticles (MNPs) was mixed with polydimethylsiloxane (PDMS)-based block copolymer. When applied together by a simple spray coating method, these materials formed a film...
February 21, 2018: ACS Applied Materials & Interfaces
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