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Hasan jilaihawi

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https://www.readbyqxmd.com/read/27815101/cerebral-embolic-protection-during-transcatheter-aortic-valve-replacement
#1
Samir R Kapadia, Susheel Kodali, Raj Makkar, Roxana Mehran, Ronald M Lazar, Robert Zivadinov, Michael G Dwyer, Hasan Jilaihawi, Renu Virmani, Saif Anwaruddin, Vinod H Thourani, Tamim Nazif, Norman Mangner, Felix Woitek, Amar Krishnaswamy, Stephanie Mick, Tarun Chakravarty, Mamoo Nakamura, James M McCabe, Lowell Satler, Alan Zajarias, Wilson Y Szeto, Lars Svensson, Maria C Alu, Roseann M White, Carlye Kraemer, Azin Parhizgar, Martin B Leon, Axel Linke
BACKGROUND: Neurological events and brain infarction after transcatheter aortic valve replacement (TAVR) are concerns which may be reduced with transcatheter embolic protection (TEP). OBJECTIVE: Evaluate the safety and efficacy of TEP during TAVR. METHODS: Nineteen centers randomized 363 patients undergoing TAVR to safety (n=123), device imaging (n=121), and control imaging (n=119). The primary safety endpoint was major adverse cardiac and cerebrovascular events (MACCE) at 30 days and the primary efficacy endpoint was reduction in new lesion volume in protected brain territories on MRI scans at 2-7 days...
October 27, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27705892/sapien-3-transcatheter-aortic-valve-implantation-with-moderate-or-without-predilation
#2
Yigal Abramowitz, Hasan Jilaihawi, Tarun Chakravarty, Yoshio Maeno, Hiroyuki Kawamori, Yoshio Kazuno, Geeteshwar Mangat, Tanya Rami, Zev Allison, David Anderson, Larry Chan, Wen Cheng, Raj R Makkar
OBJECTIVES: Aortic valve preparation with balloon aortic valvuloplasty (BAV) has been previously considered mandatory during transcatheter aortic valve implantation (TAVI) procedures. BAV-inherent risks including stroke, conduction abnormalities, and reduced device profile size established the rationale for safe valve deployment without the need for aggressive valve preparation. We investigate the feasibility and safety of performing Sapien 3 (S3; Edwards Lifesciences) balloon-expandable TAVI with moderate or without predilation (PD)...
October 2016: Journal of Invasive Cardiology
https://www.readbyqxmd.com/read/27640027/leaflet-motion-abnormality-after-tavi-genuine-threat-or-much-ado-about-nothing
#3
Tarun Chakravarty, Yigal Abramowitz, Hasan Jilaihawi, Raj R Makkar
Symptomatic transcatheter heart valve (THV) thrombosis is noted in up to 1% of patients after transcatheter aortic valve replacement. Recently, hypoattenuated leaflet thickening and reduced leaflet motion of bioprosthetic aortic valves associated with normal transvalvular gradients (and possibly related to subclinical leaflet thrombosis) have been reported. While trans-thoracic echocardiography is a useful initial screening imaging modality for the detection of symptomatic THV thrombosis associated with elevated transvalvular gradients, it has limited utility in the detection of subclinical THV thrombosis...
September 18, 2016: EuroIntervention
https://www.readbyqxmd.com/read/27623462/association-between-transcatheter-aortic-valve-replacement-and-subsequent-infective-endocarditis-and-in-hospital-death
#4
Ander Regueiro, Axel Linke, Azeem Latib, Nikolaj Ihlemann, Marina Urena, Thomas Walther, Oliver Husser, Howard C Herrmann, Luis Nombela-Franco, Asim N Cheema, Hervé Le Breton, Stefan Stortecky, Samir Kapadia, Antonio L Bartorelli, Jan Malte Sinning, Ignacio Amat-Santos, Antonio Munoz-Garcia, Stamatios Lerakis, Enrique Gutiérrez-Ibanes, Mohamed Abdel-Wahab, Didier Tchetche, Luca Testa, Helene Eltchaninoff, Ugolino Livi, Juan Carlos Castillo, Hasan Jilaihawi, John G Webb, Marco Barbanti, Susheel Kodali, Fabio S de Brito, Henrique B Ribeiro, Antonio Miceli, Claudia Fiorina, Guglielmo Mario Actis Dato, Francesco Rosato, Vicenç Serra, Jean-Bernard Masson, Harindra C Wijeysundera, Jose A Mangione, Maria-Cristina Ferreira, Valter C Lima, Luiz A Carvalho, Alexandre Abizaid, Marcos A Marino, Vinicius Esteves, Julio C M Andrea, Francesco Giannini, David Messika-Zeitoun, Dominique Himbert, Won-Keun Kim, Costanza Pellegrini, Vincent Auffret, Fabian Nietlispach, Thomas Pilgrim, Eric Durand, John Lisko, Raj R Makkar, Pedro A Lemos, Martin B Leon, Rishi Puri, Alberto San Roman, Alec Vahanian, Lars Søndergaard, Norman Mangner, Josep Rodés-Cabau
IMPORTANCE: Limited data exist on clinical characteristics and outcomes of patients who had infective endocarditis after undergoing transcatheter aortic valve replacement (TAVR). OBJECTIVE: To determine the associated factors, clinical characteristics, and outcomes of patients who had infective endocarditis after TAVR. DESIGN, SETTING, AND PARTICIPANTS: The Infectious Endocarditis after TAVR International Registry included patients with definite infective endocarditis after TAVR from 47 centers from Europe, North America, and South America between June 2005 and October 2015...
September 13, 2016: JAMA: the Journal of the American Medical Association
https://www.readbyqxmd.com/read/27609683/transcatheter-aortic-valve-replacement-for-bicuspid-aortic-stenosis-are-we-ready-for-the-challenge
#5
EDITORIAL
Raj Makkar, Tarun Chakravarty, Hasan Jilaihawi
No abstract text is available yet for this article.
September 13, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27497364/the-clinical-impact-of-vascular-complications-as-defined-by-varc-1-vs-varc-2-in-patients-following-transcatheter-aortic-valve-implantation
#6
Kazuaki Okuyama, Hasan Jilaihawi, Yigal Abramowitz, Mohammad Kashif, Jigar Patel, Heera Pokhrel, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, Raj Makkar
AIMS: The Valve Academic Research Consortium (VARC) recommendations were devised to standardise clinical endpoint definitions which best reflect the safety and efficacy of transcatheter aortic valve implantation (TAVI). The categorisation of vascular complications (VC) is greatly affected by the definition, but the impact of its change is unclear. We sought to compare VC between VARC-1 and VARC-2 definitions as a predictor for survival. METHODS AND RESULTS: A series of 376 patients undergoing TAVI by the transfemoral or transapical approach was studied...
2016: EuroIntervention
https://www.readbyqxmd.com/read/27424244/aortic-angulation-attenuates-procedural-success-following-self-expandable-but%C3%A2-not-balloon-expandable-tavr
#7
Yigal Abramowitz, Yoshio Maeno, Tarun Chakravarty, Yoshio Kazuno, Nobuyuki Takahashi, Hiroyuki Kawamori, Geeteshwar Mangat, Wen Cheng, Hasan Jilaihawi, Raj R Makkar
OBJECTIVES: The aim of this study was to evaluate the impact of increased aortic angulation (AA) on acute procedural success following transcatheter aortic valve replacement (TAVR). BACKGROUND: The degree of angulation between the aorta and the heart can make accurate positioning of the bioprosthesis during TAVR more demanding, particularly in instances of an extremely angulated or horizontal aortic root. Nonetheless, there are limited data on the impact of AA on the acute success of TAVR...
August 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27372022/a-bicuspid-aortic-valve-imaging-classification-for-the-tavr-era
#8
Hasan Jilaihawi, Mao Chen, John Webb, Dominique Himbert, Carlos E Ruiz, Josep Rodés-Cabau, Gregor Pache, Antonio Colombo, Georg Nickenig, Michael Lee, Corrado Tamburino, Horst Sievert, Yigal Abramowitz, Giuseppe Tarantini, Faisal Alqoofi, Tarun Chakravarty, Mohammad Kashif, Nobuyuki Takahashi, Yoshio Kazuno, Yoshio Maeno, Hiroyuki Kawamori, Alaide Chieffo, Philipp Blanke, Danny Dvir, Henrique Barbosa Ribeiro, Yuan Feng, Zhen-Gang Zhao, Jan-Malte Sinning, Chad Kliger, Gennaro Giustino, Basia Pajerski, Sebastiano Imme, Eberhard Grube, Jonathon Leipsic, Alec Vahanian, Iassen Michev, Vladimir Jelnin, Azeem Latib, Wen Cheng, Raj Makkar
OBJECTIVES: This study sought to evaluate transcatheter aortic valve replacement (TAVR) in bicuspid aortic valve (BAV) aortic stenosis (AS), with a particular emphasis on TAVR-directed bicuspid aortic valve imaging (BAVi) of morphological classification. BACKGROUND: TAVR has been used to treat BAV-AS but with heterogeneous outcomes and uncertainty regarding the relevance of morphology. METHODS: In 14 centers in the United States, Canada, Europe, and Asia, 130 BAV-AS patients underwent TAVR...
June 29, 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27219874/outcome-of-paravalvular-leak-repair-after-transcatheter-aortic-valve-replacement-with-a-balloon-expandable-prosthesis
#9
Abhijeet Dhoble, Tarun Chakravarty, Mamoo Nakamura, Yigal Abramowitz, Rikin Tank, Hirotsugu Mihara, Geeteshwar Mangat, Hasan Jilaihawi, Takahiro Shiota, Raj Makkar
BACKGROUND: Significant paravalvular leak (PVL) occurs in up to 13% of patients after transcatheter aortic valve replacement (TAVR) with a balloon-expandable bioprosthesis. Transcatheter PVL repair has emerged as a less invasive alternative for this problem. OBJECTIVES: The aim of this study was to evaluate the safety, feasibility, and clinical outcomes of transcatheter PVL repair after TAVR with balloon-expandable valve. METHODS: We retrospectively identified 15 patients who underwent 16 PVL repair procedures after the TAVR at our center...
May 24, 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/27056310/paravalvular-regurgitation-after-transcatheter-aortic-valve-replacement-striving-to-perfect-its-prognostic-evaluation-with-hemodynamic-data
#10
EDITORIAL
Hasan Jilaihawi
No abstract text is available yet for this article.
April 11, 2016: JACC. Cardiovascular Interventions
https://www.readbyqxmd.com/read/27025512/geometric-changes-in-ventriculoaortic-complex-after-transcatheter-aortic-valve-replacement-and-its-association-with-post-procedural-prosthesis-patient-mismatch-an-intraprocedural-3d-tee-study
#11
Hiroto Utsunomiya, Hirotsugu Mihara, Yuji Itabashi, Sayuki Kobayashi, Robert J Siegel, Tarun Chakravarty, Hasan Jilaihawi, Raj R Makkar, Takahiro Shiota
AIMS: Prosthesis-patient mismatch (PPM) after transcatheter aortic valve replacement (TAVR) leads to increased mortality. However, its peri-procedural determinants remain unknown. We investigated geometric changes in aortic annulus (AoA) and left ventricular outflow tract (LVOT) during TAVR by three-dimensional transoesophageal echocardiography (3D-TEE) and its association with post-procedural PPM. METHODS AND RESULTS: A total of 131 patients with severe aortic stenosis underwent intraprocedural 3D-TEE during balloon-expandable TAVR...
March 29, 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/27015888/impact-of-diabetes-mellitus-on-outcomes-after-transcatheter-aortic-valve-implantation
#12
Yigal Abramowitz, Hasan Jilaihawi, Tarun Chakravarty, Geeteshwar Mangat, Yoshio Maeno, Yoshio Kazuno, Nobuyuki Takahashi, Hiroyuki Kawamori, Wen Cheng, Raj R Makkar
Several clinical variables have been identified as predictors of clinical outcome after transcatheter aortic valve implantation (TAVI). Nonetheless, there is limited and contradictive data on the impact of diabetes mellitus (DM) on the prognosis of patients who undergo TAVI. We aimed to investigate the clinical characteristics and the early and midterm outcomes after TAVI according to DM status. From 802 consecutive patients who underwent TAVI, we compared 548 patients with no DM to 254 patients with diabetes (177 orally treated and 77 insulin treated)...
May 15, 2016: American Journal of Cardiology
https://www.readbyqxmd.com/read/27002141/comparison-of-sapien-3-and-sapien-xt-transcatheter-heart-valve-stent-frame-expansion-evaluation-using-multi-slice-computed-tomography
#13
Yoshio Kazuno, Yoshio Maeno, Hiroyuki Kawamori, Nobuyuki Takahashi, Yigal Abramowitz, Hariri Babak, Mohammad Kashif, Tarun Chakravarty, Mamoo Nakamura, Wen Cheng, John Friedman, Daniel Berman, Raj R Makkar, Hasan Jilaihawi
AIMS: Stent-frame morphology of the newer-generation, balloon-expandable transcatheter heart valve (THV), the SAPIEN 3 (S3), after transcatheter aortic valve implantation (TAVI) is unknown. We evaluated the THV stent-frame morphology post TAVI of the S3 using multi-slice computed tomography (MSCT) compared with the prior-generation THV, SAPIEN XT (S-XT). METHODS AND RESULTS: A total of 94 consecutive participants of RESOLVE registry (NCT02318342) had MSCT after balloon-expandable TAVI (S3 = 39 and S-XT = 55)...
September 2016: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/26916485/outcomes-in-patients-with-transcatheter-aortic-valve-replacement-and-left-main%C3%A2-stenting-the-tavr-lm-registry
#14
MULTICENTER STUDY
Tarun Chakravarty, Rahul Sharma, Yigal Abramowitz, Samir Kapadia, Azeem Latib, Hasan Jilaihawi, Kanhaiya Lal Poddar, Gennaro Giustino, Henrique B Ribeiro, Didier Tchetche, Benoit Monteil, Luca Testa, Giuseppe Tarantini, Michela Facchin, Thierry Lefèvre, Brian R Lindman, Babak Hariri, Jigar Patel, Nobuyuki Takahashi, George Matar, James Mirocha, Wen Cheng, Murat E Tuzcu, Horst Sievert, Josep Rodés-Cabau, Antonio Colombo, Ariel Finkelstein, Jean Fajadet, Raj R Makkar
BACKGROUND: A percutaneous approach with transcatheter aortic valve replacement (TAVR) and percutaneous coronary intervention (PCI) of the left main coronary artery (LM) is frequently used in high-risk patients with coexisting aortic stenosis and LM disease. Outcomes of TAVR plus LM PCI have not been previously reported. OBJECTIVES: The primary objective of the TAVR-LM registry is to evaluate clinical outcomes in patients undergoing TAVR plus LM PCI. METHODS: Clinical, echocardiographic, computed tomographic, and angiographic characteristics were retrospectively collected in 204 patients undergoing TAVR plus LM PCI...
March 1, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/26897291/feasibility-and-safety-of-balloon-expandable-transcatheter-aortic-valve-implantation-with-moderate-or-without-predilatation
#15
Yigal Abramowitz, Hasan Jilaihawi, Tarun Chakravarty, Mohammad Kashif, George Matar, Babak Hariri, Jigar Patel, Rahul P Sharma, Wen Cheng, Raj R Makkar
AIMS: Aortic valve preparation by performing balloon aortic valvuloplasty (BAV) has always been considered mandatory during transcatheter aortic valve implantation (TAVI) procedures. We aimed to investigate the feasibility and safety of performing balloon-expandable TAVI with moderate or with no predilatation (PD). METHODS AND RESULTS: Overall, 121 patients underwent TAVI with no PD and 392 with moderate PD. TAVI endpoints and adverse events were considered according to the Valve Academic Research Consortium (VARC)-2 definitions...
February 2016: EuroIntervention
https://www.readbyqxmd.com/read/26777225/3d-assessment-of-features-associated-with-transvalvular-aortic-regurgitation-after-tavr-a-real-time-3d-tee-study
#16
Kentaro Shibayama, Hirotsugu Mihara, Hasan Jilaihawi, Javier Berdejo, Kenji Harada, Yuji Itabashi, Robert Siegel, Raj R Makkar, Takahiro Shiota
OBJECTIVES: This study of 3-dimensional (3D) transesophageal echocardiography (TEE) aimed to demonstrate features associated with transvalvular aortic regurgitation (AR) after transcatheter aortic valve replacement (TAVR) and to confirm the fact that a gap between the native aortic annulus and prosthesis is associated with paravalvular AR. BACKGROUND: The mechanism of AR after TAVR, particularly that of transvalvular AR, has not been evaluated adequately. METHODS: All patients with severe aortic stenosis who underwent TAVR with the Sapien device (Edwards Lifesciences, Irvine, California) had 3D TEE of the pre-procedural native aortic annulus and the post-procedural prosthetic valve...
February 2016: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/26756702/impact-of-body-mass-index-on-the-outcomes-following-transcatheter-aortic-valve-implantation
#17
Yigal Abramowitz, Tarun Chakravarty, Hasan Jilaihawi, Justin Cox, Rahul P Sharma, Geeteshwar Mangat, Mamoo Nakamura, Wen Cheng, Raj R Makkar
OBJECTIVES: To investigate the influence of body mass index (BMI) on short- and midterm outcomes following transcatheter aortic valve implantation (TAVI). BACKGROUND: Although obesity is a major risk factor for cardiovascular mortality, numerous studies reported a beneficial effect of obesity on survival in patients with cardiovascular disease and in patients after cardiac interventions. Moreover, all previous reports examining the relation between BMI and outcomes following TAVI have underscored the "obesity paradox" in these patients...
July 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/26602075/impact-of-preprocedural-b-type-natriuretic-peptide-levels-on-the-outcomes-after-transcatheter-aortic-valve-implantation
#18
Yigal Abramowitz, Tarun Chakravarty, Hasan Jilaihawi, Chin Lee, Justin Cox, Rahul P Sharma, Geeteshwar Mangat, Wen Cheng, Raj R Makkar
There are limited data on the effect of baseline B-type natriuretic peptide (BNP) on the outcome after transcatheter aortic valve implantation (TAVI). We investigated the influence of baseline BNP levels on the short-term and midterm clinical outcomes after TAVI. During a 3-year period, 780 patients with severe aortic stenosis underwent TAVI at our institute and had baseline BNP levels. We compared the high, mid, and low tertiles of BNP levels. TAVI end points, device success, and adverse events were considered according to the Valve Academic Research Consortium 2 definitions...
December 15, 2015: American Journal of Cardiology
https://www.readbyqxmd.com/read/26527374/balloon-expandable-transcatheter-aortic-valve-replacement-in-patients-with-extreme-aortic-valve-calcification
#19
Yigal Abramowitz, Hasan Jilaihawi, Tarun Chakravarty, Mohammad Kashif, George Matar, Babak Hariri, Jigar Patel, Mamoo Nakamura, Wen Cheng, Raj R Makkar
OBJECTIVES: To assess the procedural and short-term clinical outcome of performing balloon-expandable TAVR in patients with extremely calcified aortic valves. BACKGROUND: Quantity of aortic valve calcification predicts rates of paravalvular regurgitation (PVR) post transcatheter aortic valve replacement (TAVR). Nonetheless, short-term outcomes of balloon-expandable TAVR in patients with extremely high calcified aortic valves have not been previously described. METHODS: We studied patients with severe aortic stenosis that underwent balloon-expandable TAVR and had a pre-procedural non-contrast CT...
May 2016: Catheterization and Cardiovascular Interventions
https://www.readbyqxmd.com/read/26493666/mitral-annulus-calcification
#20
REVIEW
Yigal Abramowitz, Hasan Jilaihawi, Tarun Chakravarty, Michael J Mack, Raj R Makkar
Mitral annulus calcification (MAC) is a chronic, degenerative process in the fibrous base of the mitral valve. Although MAC was initially thought to be an age-related degenerative process, there is accumulating evidence that other mechanisms, such as atherosclerosis and abnormal calcium-phosphorus metabolism, also contribute to the development of MAC. Despite its frequency, the clinical relevance of MAC is grossly underappreciated. Indeed, MAC is associated with an increased incidence of cardiovascular disease, mitral valve disease, arrhythmias, and mortality...
October 27, 2015: Journal of the American College of Cardiology
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