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https://www.readbyqxmd.com/read/28381774/interfacial-properties-of-binary-systems-composed-of-dppc-and-perfluorinated-double-long-chain-salts-with-divalent-counterions-of-separate-electric-charge
#1
Riku Kato, Hiromichi Nakahara, Osamu Shibata
The interfacial behavior of binary monolayers of 1,1'-(1,ω-alkanediyl)-bispyridinium perfluorotetradecanecarboxylate (CnBP(FC14)2, n = 2, 6, or 10) and dipalmitoylphosphatidylcholine (DPPC) was studied using surface pressure (π)-area (A) and surface potential (ΔV)-A isotherm measurements and morphological observations. In a previous study, we showed that the spacer moieties of C2BP(FC14)2 and C6BP(FC14)2 are completely dissociated after spreading on 0.15 M NaCl, whereas the C10BP(FC14)2 spacer moieties do not dissociate in the monolayer state...
April 4, 2017: Journal of Oleo Science
https://www.readbyqxmd.com/read/28369524/ngscheckmate-software-for-validating-sample-identity-in-next-generation-sequencing-studies-within-and-across-data-types
#2
Sejoon Lee, Soohyun Lee, Scott Ouellette, Woong-Yang Park, Eunjung A Lee, Peter J Park
In many next-generation sequencing (NGS) studies, multiple samples or data types are profiled for each individual. An important quality control (QC) step in these studies is to ensure that datasets from the same subject are properly paired. Given the heterogeneity of data types, file types and sequencing depths in a multi-dimensional study, a robust program that provides a standardized metric for genotype comparisons would be useful. Here, we describe NGSCheckMate, a user-friendly software package for verifying sample identities from FASTQ, BAM or VCF files...
March 23, 2017: Nucleic Acids Research
https://www.readbyqxmd.com/read/28368610/bax-activation-blocks-self-renewal-and-induces-apoptosis-of-human-glioblastoma-stem-cells
#3
Simona Daniele, Deborah Pietrobono, Barbara Costa, Mariateresa Giustiniano, Valeria La Pietra, Chiara Giacomelli, Giuseppe La Regina, Romano Silvestri, Sabrina Taliani, Maria Letizia Trincavelli, Federico Da Settimo, Ettore Novellino, Claudia Martini, Luciana Marinelli
Glioblastoma (GBM) is characterized by a poor response to conventional chemotherapeutic agents, attributed to the insurgence of drug resistance mechanisms and to the presence of a subpopulation of glioma stem cells (GSCs). GBM cells and GSCs present, among others, an overexpression of antiapoptotic proteins and an inhibition of pro-apoptotic ones, which help to escape apoptosis. Among pro-apoptotic inducers, the Bcl-2 family protein Bax has recently emerged as a promising new target in cancer therapy along with first BAX activators (BAM7, Compound 106, and SMBA1)...
April 11, 2017: ACS Chemical Neuroscience
https://www.readbyqxmd.com/read/28363960/genetic-in-stability-of-2-6-dichlorobenzamide-bam-catabolism-in-aminobacter-sp-msh1-biofilms-under-carbon-starved-conditions
#4
Benjamin Horemans, Bart Raes, Hannelore Brocatus, Jeroen T'Syen, Caroline Rombouts, Lynn Vanhaecke, Johan Hofkens, Dirk Springael
Aminobacter sp. MSH1 grows on and mineralizes the groundwater micropollutant 2,6-dichlorobenzamide (BAM) and is of interest for BAM removal in drinking water treatment plants (DWTPs). The BAM-catabolic genes in MSH1 are located on plasmid pBAM1 carrying bbdA encoding the conversion of BAM to 2,6-dichlorobenzoic acid (2,6-DCBA) (BbdA(+) phenotype) and plasmid pBAM2 carrying gene clusters encoding the conversion of 2,6-DCBA to TCA cycle intermediates (Dcba(+) phenotype). Indications exist that MSH1 loses easily its BAM-catabolic phenotype...
March 31, 2017: Applied and Environmental Microbiology
https://www.readbyqxmd.com/read/28345496/toward-a-better-nutritional-aiding-in-disasters-relying-on-lessons-learned-during-the-bam-earthquake
#5
Mahmoud Nekouie Moghadam, Mohammadreza Amiresmaieli, Mohammad Hassibi, Farideh Doostan, Sajad Khosravi
Introduction Examining various problems in the aftermath of disasters is very important to the disaster victims. Managing and coordinating food supply and its distribution among the victims is one of the most important problems after an earthquake. Therefore, the purpose of this study was to recognize problems and experiences in the field of nutritional aiding during an earthquake. METHODS: This qualitative study was of phenomenological type. Using the purposive sampling method, 10 people who had experienced nutritional aiding during the Bam Earthquake (Iran; 2003) were interviewed...
March 27, 2017: Prehospital and Disaster Medicine
https://www.readbyqxmd.com/read/28342886/using-genetic-data-to-improve-species-distribution-models
#6
Jérémy Bouyer, Renaud Lancelot
Tsetse flies (Diptera, Glossinidae) transmit human and animal trypanosomoses in Africa, respectively a neglected human disease (sleeping sickness) and the most important constraint to cattle production in infested countries (nagana). We recently developed a methodology to map landscape friction (i.e. resistance to movement) for tsetse in West Africa. The goal was to identify natural barriers to tsetse dispersal, and potentially isolated tsetse populations for targeting elimination programmes. Most species distribution models neglect landscape functional connectivity whereas environmental factors affecting suitability or abundance are not necessarily the same as those influencing gene flows...
March 23, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/28335456/mosquito-traps-an-innovative-environmentally-friendly-technique-to-control-mosquitoes
#7
Brigitte Poulin, Gaëtan Lefebvre, Camille Muranyi-Kovacs, Samuel Hilaire
We tested the use of mosquito traps as an alternative to spraying insecticide in Camargue (France) following the significant impacts observed on the non-target fauna through Bti persistence and trophic perturbations. In a village of 600 inhabitants, 16 Techno Bam traps emitting CO₂ and using octenol lures were set from April to November 2016. Trap performance was estimated at 70% overall based on mosquitoes landing on human bait in areas with and without traps. The reduction of Ochlerotatus caspius and Oc...
March 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28330727/evaluation-of-bam-butorphanol-azaperone-medetomidine-in-captive-african-lion-panthera-leo-immobilization
#8
Aleksandr Semjonov, Vladimir Andrianov, Jacobus P Raath, Toomas Orro, Derik Venter, Liesel Laubscher, Silke Pfitzer
OBJECTIVE: The combination of butorphanol, azaperone and medetomidine (BAM) with subsequent antagonism by naltrexone-yohimbine or naltrexone-atipamezole was evaluated for reversible immobilization of captive African lions (Panthea leo). STUDY DESIGN: Prospective, clinical trial. ANIMALS: Twenty lions, 11 males and nine females, weighing 38-284 kg were immobilized in South Africa. METHODS: The BAM volume dose rate administered was 0...
February 8, 2017: Veterinary Anaesthesia and Analgesia
https://www.readbyqxmd.com/read/28328004/red-ml-a-novel-effective-rna-editing-detection-method-based-on-machine-learning
#9
Heng Xiong, Dongbing Liu, Qiye Li, Mengyue Lei, Liqin Xu, Liang Wu, Zongji Wang, Shancheng Ren, Wangsheng Li, Min Xia, Lihua Lu, Haorong Lu, Yong Hou, Shida Zhu, Xin Liu, Yinghao Sun, Jian Wang, Huanming Yang, Kui Wu, Xun Xu, Leo J Lee
Background: With the advancement of second generation sequencing techniques, our ability to detect and quantify RNA editing on a global scale has been vastly improved. As a result, RNA editing is now being studied under a growing number of biological conditions so that its biochemical mechanisms and functional roles can be further understood. However, a major barrier that prevents RNA editing from being a routine RNA-seq analysis, similar to gene expression and splicing analysis for example, is the lack of user-friendly and effective computational tools...
March 2, 2017: GigaScience
https://www.readbyqxmd.com/read/28324725/tailoring-a-compact-and-stable-langmuir-bi-dimensional-pbx-based-layered-perovskite-film-at-the-air-water-interface-and-on-solid-support
#10
Luisa Ariza-Carmona, Gonzalo García-Espejo, María T Martín-Romero, Luis Camacho
The present work studies the stability of Langmuir organic-inorganic superlattice materials thin films consisting of layered perovskite-based films with controlled 2D framework as well as to design experimental conditions for increasing the efficiency of the organic-inorganic perovskite motif by mechanical stimulus. Therefore, a whole covering of the air/water interface by a compact and stable lead-based layered perovskite structure is pursued. A 2D layered perovskite-type hybrid structure of the form [(CH3(CH2)19NH3)2(PbX4)], X=Cl, and Br, in which, two-dimensional sheets stabilized by a inner bilayer of organic monoammonium cation matrix, is mechanically tailored by successive compression-expansion cycles...
March 14, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28315838/germline-proliferation-is-regulated-by-somatic-endocytic-genes-via-jnk-and-bmp-signaling-in-drosophila
#11
Yaning Tang, Qing Geng, Di Chen, Shaowei Zhao, Xian Liu, Zhaohui Wang
Signals derived from the microenvironment contribute greatly to tumorigenesis. The underlying mechanism requires thorough investigation. Here, we use Drosophila testis as a model system to address this question, taking the advantage of the ease to distinguish germline and somatic cells and to track the cell numbers. In an EMS mutagenesis screen, we identified Rab5, a key factor in endocytosis, for its non-autonomous role in germline proliferation. The disruption of Rab5 in somatic cyst cells, which escort the development of germline lineage, induced the over-proliferation of under-differentiated but genetically wild-type germ cells...
March 17, 2017: Genetics
https://www.readbyqxmd.com/read/28290215/genetic-assessment-of-leech-species-from-yak-bos-grunniens-in-the-tract-of-northeast-india
#12
Nilkantha Chatterjee, Bishal Dhar, Debasis Bhattarcharya, Sourabh Deori, Juwar Doley, Joken Bam, Pranab J Das, Asit K Bera, Sitangshu M Deb, Ningthoujam Neelima Devi, Rajesh Paul, Sorokhaibam Malvika, Sankar Kumar Ghosh
Yak is an iconic symbol of Tibet and high altitudes of Northeast India. It is highly cherished for milk, meat, and skin. However, yaks suffer drastic change in milk production, weight loss, etc, when infested by parasites. Among them, infestation by leeches is a serious problem in the Himalayan belt of Northeast India. The parasite feeds on blood externally or from body orifices, like nasopharynx, oral, rectum, etc. But there has been limited data about the leech species infesting the yak in that region because of the difficulties in morphological identification due to plasticity of the body, changes in shape, and surface structure and thus, warrants for the molecular characterization of leech...
March 14, 2017: Mitochondrial DNA. Part A. DNA Mapping, Sequencing, and Analysis
https://www.readbyqxmd.com/read/28289682/stent-grafts-can-convert-unusable-upper-arm-arteriovenous-fistulas-into-a-functioning-hemodialysis-access-a-retrospective-case-series
#13
Charudatta S Bavare, Tiffany K Street, Eric K Peden, Mark G Davies, Joseph J Naoum
INTRODUCTION: Not all newly created arteriovenous fistulas (AVFs) successfully mature and develop into a functioning access for hemodialysis. Percutaneous transluminal angioplasty (PTA) and balloon-assisted maturation (BAM) have been utilized to either treat flow-limiting stenoses or to promote and accelerate maturation. We hypothesized that unusable upper arm AVFs can be rescued by conversion to a functional access using the percutaneous placement of a stent graft (SG). METHODS: Clinical data on 12 patients with an early non-usable upper arm AVF underwent percutaneous revision using SGs...
2017: Frontiers in Surgery
https://www.readbyqxmd.com/read/28288854/irinotecan-induced-bile-acid-malabsorption-is-associated-with-down-regulation-of-ileal-asbt-slc10a2-in-mice
#14
A-Xi Shi, Yan Zhou, Xiao-Yi Zhang, Yan-Shu Zhao, Hong-Yan Qin, Yan-Ping Wang, Xin-An Wu
Irinotecan, (CPT-11), an antitumor agent primarily used for the treatment of solid tumors, has often compromised clinical application due to the inducement of severe delay-onset diarrhea. Bile acid malabsorption (BAM) is widely accepted as the common cause of diarrhea. However, whether CPT-11-induced diarrhea has correlation with BAM is unknown. The aim of this study was to investigate the effect of CPT-11 on the bile acid homeostasis in mice. The mice were administrated with CPT-11 intravenously for four consecutive days...
March 10, 2017: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28286814/trends-of-serum-electrolyte-changes-in-crush-syndrome-patients-of-bam-earthquake-a-cross-sectional-study
#15
Saeed Safari, Mehdi Eshaghzade, Iraj Najafi, Alireza Baratloo, Behrooz Hashemi, Mohammad Mehdi Forouzanfar, Farhad Rahmati
INTRODUCTION: Electrolyte imbalances are very common among crushed earthquake victims but there is not enough data regarding their trend of changes. The present study was designed to evaluate the trend of changes in sodium, calcium, and phosphorus ions among crush syndrome patients. METHODS: In this retrospective cross-sectional study, using the database of Bam earthquake victims, which was developed by Iranian Society of Nephrology following Bam earthquake, Iran, 2003, the 10-day trend of sodium, calcium, and phosphorus ions changes in > 15 years old crush syndrome patients was evaluated...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28286812/20-day-trend-of-serum-potassium-changes-in-bam-earthquake-victims-with-crush-syndrome-a-cross-sectional-study
#16
Saeed Safari, Iraj Najafi, Mostafa Hosseini, Alireza Baratloo, Mahmoud Yousefifard, Hamidreza Mohammadi
INTRODUCTION: Many of those who survive following an earthquake die in the next phase due to preventable and treatable medical conditions such as hyperkalemia. The present study aimed to evaluate the trend of potassium changes in crush syndrome patients of Bam earthquake. METHODS: In this retrospective cross-sectional study, using the database of Bam earthquake victims, which were developed by Iranian Society of Nephrology following Bam earthquake, Iran, 2003, the 20-day trend of potassium changes in > 15 years old crush syndrome patients was evaluated...
2017: Emergency (Tehran, Iran)
https://www.readbyqxmd.com/read/28283136/temporal-dynamics-of-phlebotomine-sand-flies-population-in-response-to-ambient-temperature-variation-bam-kerman-province-of-iran
#17
Mansour Halimi, Zahra Zarei Cheghabaleki, Mohammad Jafari Modrek, Mahdi Delavari
BACKGROUND: Variations in climate condition may have changed the dynamic of zoonotic cutaneous leishmaniasis (ZCL) and its agents such as sand flies and reservoir in the Bam Kerman the dry region of Iran. OBJECTIVES: In this study we intend to examine the seasonal and interannual dynamics of the phlebotomine mosquito as a function of ambient temperature in Bam, Kerman one of the main leshmaniasis prevalence area in Iran. METHODS: The MODIS land surface temperature product (LST; MODIS/Terra LST/E Monthly L3 Global 0...
September 2016: Annals of Global Health
https://www.readbyqxmd.com/read/28276492/epitaxially-grown-bam-hexaferrite-films-having-uniaxial-axis-in-the-film-plane-for-self-biased-devices
#18
Xiaozhi Zhang, Siqin Meng, Dongsheng Song, Yao Zhang, Zhenxing Yue, Vincent G Harris
Barium hexaferrite (BaM) films with in-plane c-axis orientation are promising and technically important materials for self-biased magnetic microwave devices. In this work, highly oriented BaM films with different thickness and an in-plane easy axis (c-axis) of magnetization were grown on a-plane single-crystal sapphire substrates by direct current magnetron sputtering. A procedure involving seed layers, layer-by-layer annealing was adopted to reduce the substrate-induced strains and allow for the growth of thick (~3...
March 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28264674/epstein-barr-virus-and-cytomegalovirus-infections-and-their-clinical-relevance-in-egyptian-leukemic-pediatric-patients
#19
Samah Aly Loutfy, Maha A Abo-Shadi, Mohamed Fawzy, Mohamed El-Wakil, Shimaa A Metwally, Manar M Moneer, Nasra F Abdel Fattah, Sara Kassem, Ahmed Elgebaly
BACKGROUND: Epstein-Barr virus (EBV) and human cytomegalovirus (CMV) infections are environmental risk factors affecting the outcome of cancer due to an impairment in the cell-mediated immunity. Therefore, this study aimed to detect the frequency of EBV and CMV DNA and their association with clinical characteristics and outcome of pediatric leukemic patients. METHODS: Samples of 50 immunocompromised pediatric leukemic patients and 30 apparently healthy children were subjected to the amplification of EBV DNA by one version of PCR targeting the Bam H1 W region of the genomic region of EBV, and the amplification of CMV DNA by targeting the CMV UL97 genomic region by a second round PCR...
March 6, 2017: Virology Journal
https://www.readbyqxmd.com/read/28243654/effect-of-chirality-on-monoacylglycerol-ester-monolayer-characteristics-3-monostearoyl-sn-glycerol
#20
D Vollhardt, G Brezesinski
The effect of chirality on the thermodynamic behavior, the morphological features, and the 2D lattice structures of 3-monostearoyl-sn-glycerol monolayers is studied. The present study focusses on the influence of the alkyl chain length on the chiral discrimination. Surface pressure-area (π-A) isotherms, Brewster angle microscopy (BAM), and particularly, grazing incidence X-ray diffraction (GIXD) are the experimental basis of the presented results. The π-A isotherms of the enantiomeric 3-monostearoyl-sn-glycerol monolayers measured between 25 and 38 °C resemble those of the racemic 1-monostearoyl-rac-glycerol monolayers, thus indicating small energetic differences between the enantiomeric and the racemic forms...
February 28, 2017: Physical Chemistry Chemical Physics: PCCP
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