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C Maharajan, R Raja, Jinde Cao, G Ravi, G Rajchakit
This paper concerns the problem of enhanced results on robust finite time passivity for uncertain discrete time Markovian jumping BAM delayed neural networks with leakage delay. By implementing a proper Lyapunov-Krasovskii functional candidate, reciprocally convex combination method, and linear matrix inequality technique, we derive several sufficient conditions for varying the passivity of discrete time BAM neural networks. Further, some sufficient conditions for finite time boundedness and passivity for uncertainties are proposed by employing zero inequalities...
2018: Advances in Difference Equations
Xu Zhen, Guangbin Cheng, Hongwei Yang, Jiaheng Zhang, Jean'ne M Shreeve
3-Nitro-4-(5-nitro-1,2,4-triazol-3-yl)furazan (2), N,N'-bis(trinitroethyl)-3,5'-diamino-4-(1,2,4-triazol-3-yl)furazan (3), N,N'-bis(trinitroethyl)-3,5'-dinitramino-4-(1,2,4-triazol-3-yl)furazan (4) and eighteen nitrogen-rich salts (5a, 5b,5d⁓5i, 5g-1, 6a⁓6i) were designed and synthesized. These 4-(1,2,4-triazole-5-yl)furazan derivatives were fully characterized by IR and NMR spectra, elemental analysis, and differential scanning calorimetry (DSC). The solid-state structures of 2, 5d, 5e, 5h, 5g-1, 6g, and 6i were confirmed via single crystal X-ray analysis...
May 15, 2018: Chemistry: a European Journal
Parasmani Pageni, Peng Yang, Marpe Bam, Tianyu Zhu, Yung Pin Chen, Alan W Decho, Mitzi Nagarkatti, Chuanbing Tang
Over-prescription and improper use of antibiotics has led to the emergence of bacterial resistance, posing a major threat to public health. There has been significant interest in the development of alternative therapies and agents to combat antibiotic resistance. We report the preparation of recyclable magnetic iron oxide nanoparticles grafted with charged cobaltocenium-containing metallopolymers by surface-initiated reversible addition-fragmentation chain transfer (RAFT) polymerization. β-Lactam antibiotics were then conjugated with metallopolymers to enhance their vitality against both Gram-positive and Gram-negative bacteria...
May 3, 2018: Biomaterials
Josh P Clevenger, Walid Korani, Peggy Ozias-Akins, Scott Jackson
Accurate identification of polymorphisms from sequence data is crucial to unlocking the potential of high throughput sequencing for genomics. Single nucleotide polymorphisms (SNPs) are difficult to accurately identify in polyploid crops due to the duplicative nature of polyploid genomes leading to low confidence in the true alignment of short reads. Implementing a haplotype-based method in contrasting subgenome-specific sequences leads to higher accuracy of SNP identification in polyploids. To test this method, a large-scale 48K SNP array (Axiom Arachis2) was developed for Arachis hypogaea (peanut), an allotetraploid, in which 1,674 haplotype-based SNPs were included...
2018: Frontiers in Plant Science
Alexandra D Gurzau, Kelan Chen, Shifeng Xue, Weiwen Dai, Isabelle S Lucet, Thanh Thao Nguyen Ly, Bruno Reversade, Marnie E Blewitt, James M Murphy
Structural maintenance of chromosomes flexible hinge domain-containing 1 (Smchd1) plays important roles in epigenetic silencing and normal mammalian development. Recently, heterozygous mutations in SMCHD1 have been reported in two disparate disorders: facioscapulohumeral muscular dystrophy type 2 (FSHD2) and Bosma arhinia microphthalmia syndrome (BAMS). FSHD2-associated mutations lead to loss of function, however whether BAMS is associated with loss or gain of function mutations in SMCHD1 is unclear. Here, we have assessed the effect of SMCHD1 missense mutations from FSHD2 and BAMS patients on ATP hydrolysis activity, protein conformation and the effect of BAMS mutations on craniofacial development in a Xenopus model...
May 10, 2018: Journal of Biological Chemistry
David Ranava, Anne Caumont-Sarcos, Cécile Albenne, Raffaele Ieva
The outer membrane (OM) of Gram-negative bacteria is an essential organelle that protects cells from external aggressions and mediates the secretion of virulence factors. Efficient assembly of integral OM β-barrel proteins (OMPs) is crucial for the correct functioning of the OM. Biogenesis of OMPs occurs in a stepwise manner that is finalized by the β-barrel assembly machinery (BAM complex). Some OMPs further require the translocation and assembly module (TAM) for efficient and correct integration into the OM...
May 1, 2018: FEMS Microbiology Letters
Daniel J Sprague, Anand Singh, Jeffrey N Johnston
The discovery that a C 2 -symmetric bis(AMidine) [BAM] catalyst promotes an anti -selective addition of α-substituted α-nitro esters to imines is described, providing α-substituted α,β-diamino ester products with high diastereo- and enantioselectivity. When compared to the function of a BAM catalyst reported previously, the pair offer a rare example of diastereodivergence using a bifunctional Brønsted acid-base organocatalyst.
February 28, 2018: Chemical Science
Waqas Ahmed, Zheng-Fei Liu
Herpesviruses have developed a variety of sophisticated immune evasion strategies to establish lifelong latent infection, including the use of long non-coding RNAs (lncRNAs). In this review, we summarize the lncRNA action modes, i.e., RNA-protein, RNA-RNA, and RNA-DNA interactions, involved in regulating important aspects of immunity by controlling gene expression at various stages. Upon herpesvirus infection, host lncRNAs, such as nuclear paraspeckle assembly transcript 1, negative regulator of antiviral, and B-cell integration cluster have been functionally characterized as negative or positive antiviral regulators in the immune response...
2018: Frontiers in Immunology
Gregory Juck, Verapaz Gonzalez, Ann-Christine Olsson Allen, Meredith Sutzko, Kody Seward, Mark T Muldoon
The Romer Labs RapidChek® Listeria monocytogenes test system (Performance Tested Method ℠ 011805) was validated against the U.S. Department of Agriculture-Food Safety and Inspection Service Microbiology Laboratory Guidebook (USDA-FSIS/MLG), U.S. Food and Drug Association Bacteriological Analytical Manual (FDA/BAM), and AOAC Official Methods of Analysis ℠ (AOAC/OMA) cultural reference methods for the detection of L. monocytogenes on selected foods including hot dogs, frozen cooked breaded chicken, frozen cooked shrimp, cured ham, and ice cream, and environmental surfaces including stainless steel and plastic in an unpaired study design...
April 27, 2018: Journal of AOAC International
Chuan-Xu Wang, Xin Li
This work described a novel halotolerant phage, JMT-1, with a spherical morphology. JMT-1, which was isolated from a hypersaline lake, could produce clear plaques on Chromohalobacter sp. LY7-3. The purified virions are spherical, have no visible tail, and are about 30-50nm in diameter. JMT-1 has a wide host range, and this study showed that the phage can infect at least five halophilic bacteria. The proteins of JMT-1 were analyzed using sodium dodecyl sulfate polyacrylamide gel electrophoresis, and six proteins were detected...
April 3, 2018: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
Annette Roug, Heather Talley, Troy Davis, Marilei Roueche, Darren DeBloois
A total of 58 American beavers ( Castor canadensis) was immobilized with butorphanol, azaperone, and medetomidine (BAM) for the purpose of health assessments, sex determination, and placement of very high-frequency tail transmitters in a subset of animals. Isoflurane gas anesthesia was available to aid with induction when needed, and all animals received supplementary oxygen. Thirty-one beavers immobilized with a mean (SD) dose of 0.65 (0.15) mg/kg butorphanol, 0.22 (0.05) mg/kg azaperone, and 0.26 (0.06) mg/kg medetomidine did not require supplemental isoflurane during induction and the mean induction time was 8 min (range: 3-21 min)...
April 26, 2018: Journal of Wildlife Diseases
Ugo Carraro
Myologists working in Padua (Italy) were able to continue a half-century tradition of studies of skeletal muscles, that started with a research on fever, specifically if and how skeletal muscle contribute to it by burning bacterial toxin. Beside main publications in high-impact-factor journals by Padua myologists, I hope to convince readers (and myself) of the relevance of the editing Basic and Applied Myology (BAM), retitled from 2010 European Journal of Translational Myology (EJTM), of the institution of the Interdepartmental Research Center of Myology of the University of Padova (CIR-Myo), and of a long series of International Conferences organized in Euganei Hills and Padova, that is, the PaduaMuscleDays...
January 12, 2018: European Journal of Translational Myology
Dieter Scharnweber, Susanne Bierbaum, Cornelia Wolf-Brandstetter
DNA sequences are widely used for gene transfer into cells including a number of substrate surface based supporting systems, but due to its singular structure property profile DNA also offers multiple options for non-canonical applications. The special case of using DNA and oligodesoxyribonucleotide (ODN) structures for surface functionalization of biomedical implants is summarized here with the major focus on (i) immobilization or anchoring of nucleic acid structures on substrate surfaces, (ii) incorporation of biologically active molecules (BAM) into such systems, and (iii) biological characteristics of the resulting surfaces in vitro and in vivo...
April 23, 2018: FEBS Letters
Elena De Ponti, Sabrina Morzenti, Cinzia Crivellaro, Federica Elisei, Andrea Crespi, Luca Guerra
BACKGROUND: Motion due to patient's breathing can introduce heavy bias in PET/CT, both in image quality and quantification. AIM: To review technical aspects of the main solutions available to manage movement in PET/CT studies. METHODS: The following tools were described: Respiratory Gated (RG), Motion Free (MF), End Expiration (EE), Banana Artefact Management (BAM) and Data Driven Gating (DDG). RESULTS: The most diffused solutions (RG, MF, EE) are based on LIST mode acquisition of a PET Field of View (4D FOV), centered on the anatomical region of interest; to link PET data not only to time and to spatial position but also to the corresponding breathing phase, the synchronized acquisition of the patient's breathing curve is performed by an external tracking device...
April 19, 2018: Current Radiopharmaceuticals
Saeed Khodabakhshzadeh, Samira Amirzadeh Moradabadi, Sadegh Khodabakhshzadeh, Mohammad Baniasadi, Touraj Harati Khalilabad
Awareness of the food security status of rural population and its influencing factors is essential for policy makers, public health institutions and the development of rural programs. This descriptive cross-sectional study was conducted in 2017 on 384 rural households in Bam city. The data was collected via the 6-item USDA questionnaire. Logistic regression was used to determine the relationship between social, economic and health factors with food security. The results indicate that 35.67% of households had full food security status, 24...
January 1, 2018: Archives of Iranian Medicine
Tsuyoshi Tokusumi, Yumiko Tokusumi, Robert A Schulz
Hedgehog (Hh) pathway signaling is crucial for the maintenance of blood cell progenitors in the lymph gland hematopoietic organ present in Drosophila third instar larvae. Previous studies from our lab have likewise shown the importance of the mir-7 and bag of marbles (bam) genes in maintaining the progenitor state. Thus we sought to investigate a possible interaction between the Hh pathway and mir-7/bam in the prohemocyte population within this hematopoietic tissue. Gain of function mir-7 was able to rescue a blood cell progenitor depletion phenotype caused by Patched (Ptc) inhibition of Hh pathway signaling in these cells...
April 16, 2018: Genesis: the Journal of Genetics and Development
Tran Dang Khanh, Tran Dang Xuan
Pseudomonas syringae pv. eriobotryae causes serious stem canker in loquat ( Eriobotrya japonica ) trees. This study was conducted to determine whether plasmids are involved with its virulence. The strain NAE89, which belonged to the B group, harbored two plasmids at approximately 6.2 and 50 Mdal that caused stem canker and halo leaf spots on loquat plants. Following digestion with Bam HI and ligation into the Bam HI cloning site of the broad range host cosmid pLAFR3, four DNA fragments at 3.8, 6.6, 12.3, and 22...
April 14, 2018: Pathogens
João M Alves, David Posada
BACKGROUND: Querying cancer genomes at single-cell resolution is expected to provide a powerful framework to understand in detail the dynamics of cancer evolution. However, given the high costs currently associated with single-cell sequencing, together with the inevitable technical noise arising from single-cell genome amplification, cost-effective strategies that maximize the quality of single-cell data are critically needed. Taking advantage of previously published single-cell whole-genome and whole-exome cancer datasets, we studied the impact of sequencing depth and sampling effort towards single-cell variant detection...
April 16, 2018: Genome Medicine
Rob J A Verhoeven, Shuang Tong, Jingfeng Zong, Yixin Chen, Sai-Wah Tsao, Jianji Pan, Honglin Chen
Epstein-Barr virus (EBV) nuclear antigen 1 (EBNA1) is one of the few viral proteins expressed by EBV in nasopharyngeal carcinoma (NPC), most likely because of its essential role in maintaining the viral genome in EBV-infected cells. In NPC, EBNA1 expression is driven by the Bam HI-Q promoter (Qp), which is regulated by both cellular and viral factors. We previously determined that the expression of another group of EBV transcripts, Bam HI-A rightward transcripts (BARTs), is associated with constitutively activated nuclear factor-κB (NF-κB) signaling in NPC cells...
April 16, 2018: Cancers
Bethany A Wellen Rudd, Andrew S Vidalis, Heather C Allen
Of the major cations in seawater (Na+, Mg2+, Ca2+, K+), Ca2+ is found to be the most enriched in fine sea spray aerosols (SSA). In this work, we investigate the binding of Ca2+ to the carboxylic acid headgroup of palmitic acid (PA), a marine-abundant fatty acid, and the impact such binding has on the stability of PA monolayers in both equilibrium and non-equilibrium systems. A range of Ca2+ conditions from 10 μM to 300 mM was utilized to represent the relative concentration of Ca2+ in high and low relative humidity aerosol environments...
April 16, 2018: Physical Chemistry Chemical Physics: PCCP
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