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Emergency Medicin

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https://www.readbyqxmd.com/read/29232052/the-us-food-and-drug-administration-s-tentative-approval-process-and-the-global-fight-against-hiv
#1
Harinder Singh Chahal, Jeffrey S Murray, Martin Shimer, Peter Capella, Ryan Presto, Mary Lou Valdez, Peter G Lurie
INTRODUCTION: In 2004, the US government began to utilize the Food and Drug Administration's (USFDA) tentative approval process (tFDA) as a basis to determine which HIV drugs are appropriate to be purchased and used in resource-constrained settings. This process permits products that are not approved for marketing in the US, including medicines with active patents or marketing restrictions in the US, to be purchased and distributed in resource-constrained settings. Although the tFDA was originally intended to support the United States' President's Emergency Plan for AIDS Relief (PEPFAR), the USFDA list has become a cornerstone of international HIV programmes that support procurement of ARVs, such as the World Health Organization and the Global Fund to Fight AIDS, Tuberculosis, and Malaria...
December 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/29231878/greek-medicine-practice-at-ancient-rome-the-physician-molecularist-asclepiades
#2
Luigi Santacroce, Lucrezia Bottalico, Ioannis Alexandros Charitos
Background: In the pre-Hellenistic period, the concept of medicine was not well-defined. Usually, a disease was considered as a divine punishment and its treatment was devolved to the priests who asked for healing from the divinities. The only job that could be compared to medical practice was a kind of itinerant medicine, derived from the Egyptian therapeutic tradition based only on practical experience and performed by people that knew a number of remedies, mostly vegetable, but without any theoretical bases about the possible mechanisms of action...
December 12, 2017: Medicines (Basel, Switzerland)
https://www.readbyqxmd.com/read/29231639/emergency-medicine-in-the-general-practice-internship-in-finnmark-county
#3
Kaja Hansen Hunnålvatn, Daniela Ivan, Torben Wisborg
No abstract text is available yet for this article.
December 12, 2017: Tidsskrift for Den Norske Lægeforening: Tidsskrift for Praktisk Medicin, Ny Række
https://www.readbyqxmd.com/read/29231488/-clinical-data-analysis-of-279-inpatients-with-acupuncture-consultation-in-a-comprehensive-hospital
#4
Yamin Zhang, Hua Sun, Suhui Chen, Hong Xu, Fei Bao
OBJECTIVE: To analyze the current status of acupuncture consultation in Peking Union Medical College Hospital, which could provide references and suggestions for the development of acupuncture at comprehensive hospitals and the treatment of diseases. METHODS: The source of departments, the number of patients, the number of consultation, treatment frequency, consultation reasons and western medicine diagnosis of 279 inpatients who received acupuncture consultation were analyzed...
February 12, 2017: Zhongguo Zhen Jiu, Chinese Acupuncture & Moxibustion
https://www.readbyqxmd.com/read/29230869/microvascular-replantation-of-a-composite-facial-avulsion-in-a-24-month-old-child-after-dog-bite
#5
David Macias, Daniel I Kwon, Paul C Walker, Nathaniel R Peterson
Dog bite injuries are common sources of morbidity with an estimated incidence of 4.5 million bites per year with over 350,000 requiring treatment in the emergency room. Children under the age of 14 are most likely to be affected with a peak age of 5-9 years old. We report a case of a 24-month-old female who sustained a large composite facial avulsion injury from a pit bull dog bite. The avulsed tissue involved a substantial portion of the patient's mid-face, including the entire soft tissue of the nose, upper lip, part of the left cheek, and left oral commissure...
December 12, 2017: Microsurgery
https://www.readbyqxmd.com/read/29230501/-development-of-ground-based-physician-staffed-emergency-missions-in-the-city-of-leipzig-from-2003-to-2013
#6
K Bader, M Bernhard, A Gries, M Kaul, R Schröder, A Ramshorn-Zimmer
BACKGROUND: The annual number of physician-based emergency missions reported is continuously increasing. Data from large cities concerning this development over long periods is sparse. MATERIAL AND METHODS: In this retrospective study the charts of all ground-based physician-staffed emergency missions in the city of Leipzig for the first quarters of 2003 and 2013 were analyzed. Patient characteristics, injury and illness severities, mission location, hospital admission rate, as well as emergency interventions were collated...
December 11, 2017: Der Anaesthesist
https://www.readbyqxmd.com/read/29230413/establishment-and-application-of-prostate-cancer-circulating-tumor-cells-in-the-era-of-precision-medicine
#7
REVIEW
Yoon Seok Suh, Jae Young Joung, Sung Han Kim, Ho Kyung Seo, Jinsoo Chung, Kang Hyun Lee
Prostate cancer (PC) is the second most common cancer in men and is the fifth leading cause of cancer-related deaths worldwide. Additionally, there is concern for overdiagnosis and overtreatment of PC. Thus, selection of an appropriate candidate for active surveillance as well as more accurate and less invasive tools for monitoring advanced PC is required. Circulating tumor cells (CTCs) have emerged as a liquid biopsy tool; there have been several reports on its role, technologies, and applications to various cancers, including PC...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29230367/a-novel-approach-for-human-whole-transcriptome-analysis-based-on-absolute-gene-expression-of-microarray-data
#8
Shirley Bikel, Leonor Jacobo-Albavera, Fausto Sánchez-Muñoz, Fernanda Cornejo-Granados, Samuel Canizales-Quinteros, Xavier Soberón, Rogerio R Sotelo-Mundo, Blanca E Del Río-Navarro, Alfredo Mendoza-Vargas, Filiberto Sánchez, Adrian Ochoa-Leyva
Background: In spite of the emergence of RNA sequencing (RNA-seq), microarrays remain in widespread use for gene expression analysis in the clinic. There are over 767,000 RNA microarrays from human samples in public repositories, which are an invaluable resource for biomedical research and personalized medicine. The absolute gene expression analysis allows the transcriptome profiling of all expressed genes under a specific biological condition without the need of a reference sample. However, the background fluorescence represents a challenge to determine the absolute gene expression in microarrays...
2017: PeerJ
https://www.readbyqxmd.com/read/29230360/skin-temperature-and-reproductive-condition-in-wild-female-chimpanzees
#9
Guillaume Dezecache, Claudia Wilke, Nathalie Richi, Christof Neumann, Klaus Zuberbühler
Infrared thermal imaging has emerged as a valuable tool in veterinary medicine, in particular for evaluating reproductive processes. Here, we explored differences in skin temperature of twenty female chimpanzees in Budongo Forest, Uganda, four of which were pregnant during data collection. Based on previous literature in other mammals, we predicted increased skin temperature of maximally swollen reproductive organs of non-pregnant females when approaching peak fertility. For pregnant females, we made the same prediction because it has been argued that female chimpanzees have evolved mechanisms to conceal pregnancy, including swellings of the reproductive organs, conspicuous copulation calling, and solicitation of male mating behaviour, to decrease the infanticidal tendencies of resident males by confusing paternity...
2017: PeerJ
https://www.readbyqxmd.com/read/29229657/adapting-the-emergency-first-aid-responder-course-for-zambia-through-curriculum-mapping-and-blueprinting
#10
Jennifer L Pigoga, Charmaine Cunningham, Muhumpu Kafwamfwa, Lee A Wallis
OBJECTIVES: Community members are often the first to witness and respond to medical and traumatic emergencies, making them an essential first link to emergency care systems. The Emergency First Aid Responder (EFAR) programme is short course originally developed to help South Africans manage emergencies at the community level, pending arrival of formal care providers. EFAR was implemented in two rural regions of Zambia in 2015, but no changes were originally made to tailor the course to the new setting...
December 10, 2017: BMJ Open
https://www.readbyqxmd.com/read/29229529/evaluation-of-root-knot-nematode-disease-control-and-plant-growth-promotion-potential-of-biofertilizer-ning-shield-on-trichosanthes-kirilowii-in-the-field
#11
Chun-Hao Jiang, Ping Xie, Ke Li, Yue-Sheng Xie, Liu-Jun Chen, Jin-Suo Wang, Quan Xu, Jian-Hua Guo
Biofertilizer Ning shield was composed of different strains of plant growth promotion bacteria. In this study, the plant growth promotion and root-knot nematode disease control potential on Trichosanthes kirilowii in the field were evaluated. The application of Ning shield significantly reduced the diseases severity caused by Meloidogyne incognita, the biocontrol efficacy could reached up to 51.08%. Ning shield could also promote the growth of T. kirilowii in the field by increasing seedling emergence, height and the root weight...
November 11, 2017: Brazilian Journal of Microbiology: [publication of the Brazilian Society for Microbiology]
https://www.readbyqxmd.com/read/29229057/functional-limitations-in-adults-who-utilize-chiropractic-or-osteopathic-manipulation-in-the-united-states-analysis-of-the-2012-national-health-interview-survey
#12
Mary L Forte, Michele Maiers
OBJECTIVES: The goals of this study were to identify self-reported differences in function, comorbidities, and medical service utilization among adults who reported using chiropractic and/or osteopathic manipulation in the 2012 National Health Interview Survey, and to compare these between older and younger adults. METHODS: We conducted a descriptive study of adults aged 18 or older who were included in the 2012 National Health Interview Survey and the Alternative Medicine Questionnaire...
November 2017: Journal of Manipulative and Physiological Therapeutics
https://www.readbyqxmd.com/read/29229039/analgesia-in-patients-with-trauma-in-emergency-medicine
#13
David Häske, Bernd W Böttiger, Bertil Bouillon, Matthias Fischer, Gernot Gaier, Bernhard Gliwitzky, Matthias Helm, Peter Hilbert-Carius, Björn Hossfeld, Christoph Meisner, Benjamin Schempf, Arasch Wafaisade, Michael Bernhard
BACKGROUND: Suitable analgesic drugs and techniques are needed for the acute care of the approximately 18 200-18 400 seriously injured patients in Germany each year. METHODS: This systematic review and meta-analysis of analgesia in trauma patients was carried out on the basis of randomized, controlled trials and observational studies. A systematic search of the literature over the 10-year period ending in February 2016 was carried out in the PubMed, Google Scholar, and Springer Link Library databases...
November 17, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/29228876/crossing-professional-cultures-a-qualitative-study-of-nurses-working-in-a-medical-school
#14
Eileen McKinlay, Peter Gallagher, Bernadette Jones, Lindsay Macdonald, Christine Barthow
BACKGROUND: Leaving the nursing workforce is often seen as a loss to the profession. However some nurses maintain a current nursing registration and work outside their disciplinary field within university schools of medicine. Little is known about the nature of their work and why they choose to work in this setting. AIM: To explore and describe the experiences of nurses who work in a medical school. DESIGN: Qualitative descriptive informed by autoethnography...
December 11, 2017: Contemporary Nurse
https://www.readbyqxmd.com/read/29228837/feeling-inadequate-residents-stress-and-learning-at-primary-care-clinics-in-the-united-states
#15
Joanna Veazey Brooks, Sara J Singer, Meredith Rosenthal, Alyna T Chien, Antoinette S Peters
BACKGROUND: Educators hope that residents' experiences in primary care continuity clinics will influence more trainees to enter primary care careers. Unfortunately, evidence shows that outpatient primary care training in the United States is stressful and fails to promote primary care careers. We conducted qualitative interviews with residents to understand the source of stress and to explain this failure. METHODS: In-person individual interviews were conducted with 37 primary care residents training at outpatient clinics in the US...
December 11, 2017: Medical Teacher
https://www.readbyqxmd.com/read/29227709/a-review-study-on-the-beneficial-effects-of-baduanjin
#16
Liye Zou, Zhujun Pan, Albert Yeung, Saira Talwar, Chaoyi Wang, Yang Liu, Yankai Shu, Xiaoan Chen, Garrett Anthony Thomas
AIM: Baduanjin, a Chinese traditional Qigong exercise that focuses on a mind-body integration, is considered to be an effective exercise in promoting health. Thus, we systematically and critically evaluated the emerging literature relating to the effects of Baduanjin on health outcomes. METHODS: We used seven English-language electronic databases for the literature search. At least one health-related parameter was reported in retrievable full-text Baduanjin intervention studies...
December 11, 2017: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/29227300/exercise-testing-in-heart-failure-a-contemporary-discussion-in-an-era-of-novel-diagnostic-techniques-and-biomarkers
#17
Kegan J Moneghetti, Jeffrey W Christle, Jonathan Myers, Francois Haddad
PURPOSE OF REVIEW: The purpose of this review is to highlight recent advances in the field of exercise testing for patients with heart failure. RECENT FINDINGS: The importance of assessment of cardiorespiratory fitness (CRF) and exercise testing in heart failure is highlighted in the consensus recommendation of the American Heart Association. Contemporary studies have validated the independent and incremental strength of CRF metrics in patients with heart failure and coronary artery disease...
December 8, 2017: Current Opinion in Cardiology
https://www.readbyqxmd.com/read/29226734/emerging-first-line-treatment-options-for-bladder-cancer-a-review-of-phase-ii-and-iii-therapies-in-the-pipeline
#18
Omer Jamy, Guru Sonpavde
The treatment of urothelial carcinoma (UC) had remained unchanged for several years until the recent FDA approval of immune checkpoint inhibitors (CPIs) in the salvage setting. Novel dual CPI-CPI and CPI-chemotherapy combinations are now being investigated aggressively as first line therapy for metastatic disease. Areas Covered: We discuss the recent insights into the tumor biology of UC, which may impact the prognosis as well as assist in developing precision medicine. This is followed by an overview of existing treatment including conventional chemotherapy as well as the trials that led to the recent approval of PD-1 and PD-L1 inhibitors...
December 10, 2017: Expert Opinion on Emerging Drugs
https://www.readbyqxmd.com/read/29226349/what-do-we-know-about-coaching-in-medical-education-a-literature-review
#19
REVIEW
Ben Lovell
CONTEXT: Coaching has been employed successfully in the competitive sports, professional music, and business and corporate worlds. It is now emerging as a training modality in medical education. OBJECTIVES: This paper reviews the current evidence on coaching strategies for doctors and medical students. METHODS: An applied literature search was conducted in PubMed, MEDLINE and Web of Science. Predetermined definitions of coaching interventions and their evaluations were used to narrow 993 papers down to 21, which were included in the final review...
December 11, 2017: Medical Education
https://www.readbyqxmd.com/read/29226232/connecting-undergraduate-and-postgraduate-medical-education-through-an-elective-epa-based-transitional-year-in-acute-care-an-early-project-report
#20
Gersten Jonker, Reinier G Hoff, Stefan Max, Cor J Kalkman, Olle Ten Cate
Objective: A well-designed final year may ease the transition from medical school to postgraduate training, if it has enough depth to enable the acquisition of early specialty expertise, while keeping enough breadth to support the graduation as all-round physician. Aim of this article is to describe the design of a multidisciplinary dedicated transitional year (DTY) around the theme of recognition and initial treatment of vitally threatened patients. Methods: Undergraduate and postgraduate training directors from the departments of Anaesthesiology, Cardiology, Emergency Medicine, Intensive Care Medicine and Respiratory Medicine at UMC Utrecht and partnering hospitals have collaboratively developed and implemented a curriculum for a final year focusing on three entrustable professional activities (EPAs) in the domain of acute care...
2017: GMS Journal for Medical Education
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