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Keith A Marill, David D Salcido, Matthew L Sundermann, Allison C Koller, James J Menegazzi
OBJECTIVES: Potassium cardioplegia-induced transient asystole may conserve myocardial energy, foster chemical defribrillation, and improve VF arrest outcome. A trial of potassium infusion with or without calcium reversal was conducted to test for improvement in intra-arrest VF waveform and post-ROSC hemodynamics. METHODS: Eighteen swine were randomized to three treatment arms in two phases. VF was electrically induced and untreated for 4min. The animals then received 6min of mechanical CPR...
June 2016: Resuscitation
Sergio Raposeiras-Roubín, Alejandro Virgós-Lamela, Noelia Bouzas-Cruz, Andrea López-López, María Castiñeira-Busto, Rita Fernández-Garda, Alberto García-Castelo, Moisés Rodríguez-Mañero, José María García-Acuña, Emad Abu-Assi, José Ramón González-Juanatey
In light of the low cost, the widespread availability of the electrocardiogram, and the increasing economic burden of the health-related problems, we aimed to analyze the prognostic value of automatic frontal QRS-T angle to predict mortality in patients with left ventricular (LV) systolic dysfunction after acute myocardial infarction (AMI). About 467 consecutive patients discharged with diagnosis of AMI and with LV ejection fraction ≤40% were followed during 3.9 years (2.1 to 5.9). From them, 217 patients (47...
April 15, 2014: American Journal of Cardiology
Philippe Riegel, Laurence Jesel-Morel, Benoît Laventie, Sandrine Boisset, François Vandenesch, Gilles Prévost
We report a case of infection with coagulase-positive Staphylococcus pseudintermedius related to the implantation of a cardioverter-defribrillator device. This species is usually isolated from infected animals, and contact with a dog was the probable source of infection in this patient. This isolate produced a leukotoxin effective against human polymorphonuclear leukocytes.
March 2011: International Journal of Medical Microbiology: IJMM
K-H Ladwig, J Ronel, J Baumert, C Kolb
Currently, the method of choice for protection against sudden cardiac death for high-risk patients is ICD treatment. The CIDS study could prove a significant advantage of ICD treatment compared to amiodarone therapy. However, the survival advantages can be affected by the negative side effects of ICD therapy. The therapeutic survival function of the device is, in general, associated with a consciously experienced, at the same time completely unexpected and unprepared intracardial shock experience. Within the first year after implantation, 30-50% of patients with an ICD for secondary preventative indications experience such a shock...
June 2010: Herzschrittmachertherapie & Elektrophysiologie
Craig P Dobson, Maria Teresa La Rovere, Cara Olsen, Marino Berardinangeli, Marco Veniani, Paolo Midi, Luigi Tavazzi, Mark Haigney
BACKGROUND: Previous studies have shown that increased temporal variability of repolarization, as reflected by QT interval variability measured for 10 minutes, predicted spontaneous ventricular arrhythmias in implantable cardioverter defribrillator patients, but it is unclear how these measures perform in 24-hour recordings. METHODS: Twenty-four-hour digital Holter recordings from 372 subjects with chronic heart failure enrolled in Gruppo Italiano per lo Studio della Sopravvivenza nell'Insufficienza Cardiaca, (GISSI) Heart Failure study were analyzed using a template-matching, semiautomatic algorithm to measure QT and heart rate time series in sequential 5-minute epochs for 24 hours...
November 2009: Journal of Electrocardiology
Sheila A Doggrell
The beneficial effects of amiodarone in preventing sudden cardiac death may predominantly be in patients without coronary artery disease. The AMIOdarone Versus Implantable CardioveRTer-defibrillator trial (AMIOVIRT) compared amiodarone and an implantable cardioverter-defribrillator (ICD) in non-ischaemic dilated cardiomyopathy with non-sustained ventricular arrhythmia. The trial was discontinued at the first interim analysis, as the prospective rule for inability to demonstrate statistical significance was reached...
November 2003: Expert Opinion on Pharmacotherapy
C D Swerdlow, J Zhang
Implantable cardioverter defibrillators deliver shocks in response to electrical signals that satisfy programmed criteria for detection of VT or VF. The first step in diagnosis of inappropriate shocks in patients with ICDs is to determine if the shock was delivered in response to a true tachyarrhythmia by inspecting data stored in the ICD. Shocks occur in the absence of tachyarrhythmias because nonarrhythmic physiologic or nonphysiologic signals are oversensed by the ICD and detected as arrhythmias. Diagnosis and causes of oversensing are reviewed...
2001: Reviews in Cardiovascular Medicine
(no author information available yet)
No abstract text is available yet for this article.
September 2002: Harvard Heart Letter: From Harvard Medical School
K Sunde, T Eftestøl, C Askenberg, P A Steen
What actually occurred during the two last links in the 'chain of survival': defibrillation and advanced life support (ALS), was studied in 156 patients with cardiac arrest of cardiac aetiology using the computer recording of the defibrillator and the Utstein-style data record. Ten patients (6%) survived. The ECG artefacts caused by chest compressions enabled a detailed analysis of compression rates (median 108 min(-1)) and duration of important compression free periods. The time from initiation of monitoring during asystole until chest compressions were initiated was median 29 s, significantly shorter than during electromechanical dissociation (EMD, 109 s; P < 0...
August 1999: Resuscitation
U Meyerfeldt, A Schirdewan, M Wiedemann, H Schütt, F Zimmerman, F C Luft, R Dietz
AIMS: The purpose of our study was to investigate the electrical trigger modes of monomorphic ventricular tachycardia, by analysing stored intracardiac electrograms, and to identify haemodynamic or electrocardiographic predictors in patients with cardioverter-defribrillators. METHODS: We recorded 286 episodes of monomorphic ventricular tachycardia in 38 patients with at least three events. The electrical triggers were characterized by the morphology number, complexity, and coupling interval of premature depolarizations preceding the ventricular tachycardia...
December 1997: European Heart Journal
W S Leslie, B Fitzpatrick, C E Morrison, G C Watt, H Tunstall-Pedoe
OBJECTIVE: To assess the actual impact on coronary mortality of equipping ambulances with defibrillators. DESIGN: Retrospective analysis of routine medical and legal records of all those who had a cardiac arrest attributed to coronary heart disease occurring outside hospital in a defined population before and after the introduction of Heartstart. SETTING: City of Glasgow, North of the River Clyde, 1984 and 1990. PATIENTS: 296 and 267 men and women aged 25-64 inclusive in 1984 and 1990 respectively who had a cardiac arrest outside hospital which was attributed to coronary heart disease (International Classification of Diseases codes 410-414, ninth revision)...
February 1996: Heart: Official Journal of the British Cardiac Society
E M Breznock, K Kagan, N K Hibser
Chemical ventricular defibrillation of the heart by intravenous or intracardiac administration of bretylium tosylate (6 to 24 mg/kg of body weight) did not occur in any dog (n = 30) given the drug 5 minutes before, immediately after, or 75 seconds after electrical induction of ventricular fibrillation. The bretylium did not appear to stabilize ventricular irritability nor facilitate resuscitation by electrical defribrillation when compared with the control group of dogs. Significant dose-dependent chronotropic or systemic pressure effects were not seen following bretylium administration...
January 1977: American Journal of Veterinary Research
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