Ekaterina V Kurbatova, Allison Taylor, Victoria M Gammino, Jaime Bayona, Mercedes Becerra, Manfred Danilovitz, Dennis Falzon, Irina Gelmanova, Salmaan Keshavjee, Vaira Leimane, Carole D Mitnick, Ma Imelda Quelapio, Vija Riekstina, Piret Viiklepp, Matteo Zignol, J Peter Cegielski
The Objective of this analysis was to identify predictors of death, failure, and default among MDR-TB patients treated with second-line drugs in DOTS-plus projects in Estonia, Latvia, Philippines, Russia, and Peru, 2000-2004. Risk ratios (RR) with 95% confidence intervals (CI) were calculated using multivariable regression. Of 1768 patients, treatment outcomes were: cure/completed - 1156 (65%), died - 200 (11%), default - 241 (14%), failure - 118 (7%). Independent predictors of death included: age>45 years (RR = 1...
September 2012: Tuberculosis