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https://www.readbyqxmd.com/read/29330130/perioperative-electrophysiology-study-in-tetralogy-of-fallot-patients-undergoing-pulmonary-valve-replacement-will-identify-those-at-high-risk-for-subsequent-ventricular-tachycardia
#1
Amneet Sandhu, Emily Ruckdeschel, William H Sauer, Kathryn K Collins, Joseph Kay, Amber Khanna, James Jaggers, David Campbell, Max Mitchell, Duy T Nguyen
BACKGROUND: Ventricular tachyarrhythmias (VAs) are the most common cause of death in patients with repaired Tetralogy of Fallot (TOF), but predicting those at risk remains a challenge. Electrophysiological study (EPS) has been proposed to risk stratify TOF patients. OBJECTIVE: We sought to evaluate a perioperative EPS-guided approach to risk stratify TOF patients undergoing PVR and guide concomitant cryoablation. METHODS: A prospective cohort study of TOF patients undergoing EPS at time of PVR from 2006-present was conducted at 2 centers...
January 9, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29327439/the-hidden-concealed-left-sided-accessory-pathway-an-uncommon-cause-of-svt-in-young-people
#2
Robert H Pass, Leonardo Liberman, Eric S Silver, Christopher M Janson, Andrew D Blaufox, Lynn Nappo, Scott R Ceresnak
BACKGROUND: Concealed left sided accessory pathways (CLAP) are a cause of SVT in the young. Most are mapped with RV apical/outflow pacing. Rarely, alternative means of mapping are required. We review our experience from 3 pediatric EP centers with a rare form of "hidden" CLAP. METHODS: All patients < 21 years undergoing EP study from 2008-2014 with a "hidden" CLAP (defined as an accessory pathway (AP) for which RV pacing at CL's stable for mapping did not demonstrate eccentric retrograde conduction) were included...
January 12, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29327057/distinguishing-uveitis-secondary-to-sarcoidosis-from-idiopathic-disease-cardiac-implications
#3
Yong Seop Han, Erick Rivera-Grana, Sherveen Salek, James T Rosenbaum
Importance: Idiopathic disease is the most frequent diagnosis in a uveitis clinic. The need to distinguish sarcoidosis from idiopathic uveitis is controversial. However, cardiac involvement in sarcoidosis can be life-threatening. Objective: To report a series of patients with uveitis and cardiac sarcoidosis to illustrate the importance of categorizing the causes of uveitis. Design, Setting, and Participants: This retrospective observational case series reviewed the medical records of 249 patients with uveitis who were referred to the Casey Eye Institute between July 1, 2008, and February 28, 2017...
January 11, 2018: JAMA Ophthalmology
https://www.readbyqxmd.com/read/29326832/at-the-atrioventricular-crossroads-dual-pathway-electrophysiology-in-the-atrioventricular-node-and-its-underlying-heterogeneities
#4
Sharon A George, N Rokhaya Faye, Alejandro Murillo-Berlioz, K Benjamin Lee, Gregory D Trachiotis, Igor R Efimov
The atrioventricular node (AVN) is a complex structure that performs a variety of functions in the heart. The AVN is primarily an electrical gatekeeper between the atria and ventricles and introduces a delay between atrial and ventricular excitation, allowing for efficient ventricular filling. The AVN is composed of several compartments that safely transmit electrical excitation from the atria to the ventricles via the fast or slow pathways. There are many electrophysiological differences between these pathways, including conduction time and electrical refractoriness, that increase the predisposition of the atrioventricular junction to arrhythmias such as atrioventricular nodal re-entrant tachycardia...
December 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29326827/premature-ventricular-contraction-induced-cardiomyopathy
#5
David J Callans
Premature ventricular contractions (PVCs) are very common and usually do not require treatment. However, in the clinical setting of troublesome symptoms, or when PVCs trigger polymorphic ventricular tachycardia or cause cardiomyopathy, proper treatment is critical. In this review, the clinical syndrome of PVC-induced cardiomyopathy, including risk factors for development and treatment, is discussed. Although PVC-induced cardiomyopathy is typically associated with frequent PVCs there are also patients with this burden that do not develop cardiomyopathy, suggesting a differential susceptibility...
December 2017: Arrhythmia & Electrophysiology Review
https://www.readbyqxmd.com/read/29326113/acute-heart-failure-with-new-onset-continuous-murmur-in-a-26-year-old-man
#6
Yi-Chen Wang, Chen-Wei Huang, Ting-Wei Lin
CLINICAL INTRODUCTION: A 26-year-old man with an unremarkable medical history sensed a momentary retrosternal 'pop' followed by overwhelming dyspnoea, without reporting any prodromal symptoms. At the emergency department, he had a significant tachycardia (170 bpm) and an extreme low diastolic blood pressure (<30 mm Hg). A loud, harsh and continuous murmur could be maximally auscultated at the right lower sternal border. ECG revealed global ST depression with ST elevation in lead aVR...
January 11, 2018: Heart: Official Journal of the British Cardiac Society
https://www.readbyqxmd.com/read/29325974/fast-nonclinical-ventricular-tachycardia-inducible-after-ablation-in-patients-with-structural-heart-disease-definition-and-clinical-implications
#7
Masaya Watanabe, Marta de Riva, Sebastiaan R D Piers, Olaf M Dekkers, Micaela Ebert, Jeroen Venlet, Serge A Trines, Martin J Schalij, Daniël A Pijnappels, Katja Zeppenfeld
BACKGROUND: Noninducibility of ventricular tachycardia (VT) with an equal or longer cycle length (CL) than the clinical VT is considered the minimum ablation endpoint in patients with structural heart disease (SHD). Since their clinical relevance remains unclear, fast nonclinical VTs are often not targeted. However, an accepted definition for fast VT is lacking. The shortest possible CL of a monomorphic reentrant VT is determined by the ventricular refractory period (VRP). OBJECTIVES: We propose a patient-specific definition for fast VT based on the individual VRP (fVTVRP) and assess the prognostic significance of persistent inducibility after ablation of fVTVRP for VT recurrence...
January 8, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29325364/-the-efficacy-and-safety-of-coil-embolization-of-septal-branch-in-the-treatment-of-patients-with-obstructive-hypertrophic-cardiomyopathy
#8
H Liu, Q Wu, H W Tan, J Pang
Objective: To observe the clinical efficacy and safety of coil embolization of septal branch in the treatment of obstructive hypertrophic cardiomyopathy (HOCM). Methods: Eighteen patients with HOCM hospitalized in our department from September 2014 to October 2016 were enrolled in this study. There were 12 males and 6 females in this cohort and the age of patients ranged from 22 to 64 years old. Left ventricular outflow tract gradient (LVOTG) was derived from echocardiographic apical five-chamber view at pre-operation and at 48 hours and 6 months post operation...
December 24, 2017: Zhonghua Xin Xue Guan Bing za Zhi
https://www.readbyqxmd.com/read/29319785/diagnostic-accuracy-and-prognostic-value-of-simultaneous-hybrid-18f-fluorodeoxyglucose-positron-emission-tomography-magnetic-resonance-imaging-in-cardiac-sarcoidosis
#9
Eleanor C Wicks, Leon J Menezes, Anna Barnes, Saidi A Mohiddin, Neha Sekhri, Joanna C Porter, Helen L Booth, Emily Garrett, Riyaz S Patel, Menelaos Pavlou, Ashley M Groves, Perry M Elliott
Aims: Cardiac death is the leading cause of mortality in patients with sarcoidosis, yet cardiac involvement often remains undetected. Cardiovascular magnetic resonance imaging (CMR) and 18F-fluorodeoxyglucose (FDG)-positron emission tomography (PET) have been used to diagnose cardiac sarcoidosis (CS) yet never simultaneously in a cohort. This study sought to assess the diagnostic and prognostic utility of simultaneous hybrid cardiac PET/MR. Methods and results: Fifty-one consecutive patients with suspected CS (age 50 ± 13 years, 31 males) underwent simultaneous PET/MR following a high-fat/low-carbohydrate diet and 12-h fast...
January 8, 2018: European Heart Journal Cardiovascular Imaging
https://www.readbyqxmd.com/read/29319439/successful-management-of-minoxidil-toxicosis-in-a-dog
#10
Tyler J M Jordan, Page E Yaxley, Christine A Culler, Anusha Balakrishnan
CASE DESCRIPTION A 2-year-old sexually intact female mixed-breed dog was evaluated at an emergency hospital approximately 5 hours after ingestion of an unknown amount of over-the-counter topical hair growth promoter containing 5% minoxidil foam. Vomiting and signs of lethargy were reported by the owner, and physical examination revealed tachycardia and hypotension. No treatments were performed, and the dog was transferred to a veterinary referral hospital for management of suspected minoxidil toxicosis. CLINICAL FINDINGS On arrival at the referral hospital, the dog was tachycardic (heart rate, 200 to 220 beats/min) and hypotensive (systolic arterial blood pressure, 70 mm Hg)...
January 15, 2018: Journal of the American Veterinary Medical Association
https://www.readbyqxmd.com/read/29319218/an-uncommon-response-to-a-ventricular-extrastimulus-during-a-short-rp-supraventricular-tachycardia-what-is-the-mechanism
#11
Mitsunori Maruyama, Shunsuke Uetake, Yasushi Miyauchi, Wataru Shimizu
No abstract text is available yet for this article.
January 10, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29318626/trends-and-predictors-of-implantable-cardioverter-defibrillator-implantation-after-sudden-cardiac-arrest-insight-from-the-national-inpatient-sample
#12
Muhammad Bilal Munir, Fahad Alqahtani, Sami Aljohani, Ashwin Bhirud, Sujal Modi, Mohamad Alkhouli
BACKGROUND: Implantable cardioverter defibrillator (ICD) has a class IA indication in survivors of sudden cardiac arrest (SCA) provided no reversible cause is identified. We sought to determine trends and predictors of ICD implant in SCA patients from a national sample of United States population. METHODS AND RESULTS: Data was gathered from National Inpatient Sample (NIS) from January 2003 to December 2014. All patients ≥ 18 years of age with a primary discharge diagnosis of SCA, ventricular fibrillation (VF), ventricular flutter, and ventricular tachycardia (VT) were included...
January 9, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29317972/high-density-mapping-in-ventricular-tachycardia-ablation-a-pentaray%C3%A2-study
#13
Petra Maagh, Arnd Christoph, Henning Dopp, Markus Sebastian Mueller, Gunnar Plehn, Axel Meissner
Background: High-density mapping of ventricular tachycardia (VT) with PentaRay® (Biosense-Webster) provides high resolution with discrimination of local abnormal electrograms and slow conducting channels. We evaluate the feasibility of PentaRay® to characterize the anatomical substrate and assume an influence of the outcome despite limitations. Methods: Over a 24-month period, 26 endocardial and four epicardial maps were obtained of 26 VT patients (18 ischemic cardiomyopathy (ICM, 69...
December 2017: Cardiology Research
https://www.readbyqxmd.com/read/29316012/quality-of-life-with-ablation-or-medical-therapy-for-ventricular-arrhythmias-a-substudy-of-vanish
#14
Lorne J Gula, Steve Doucette, Peter Leong-Sit, Anthony S L Tang, Ratika Parkash, Jean-Francois Sarrazin, Bernard Thibault, Vidal Essebag, Stanley K Tung, Marc W Deyell, Jean-Marc Raymond, Chris Lane, Pablo B Nery, George D Veenhuyzen, Damian P Redfearn, Jeffrey S Healey, Jean-Francois Roux, Karen Giddens, John L Sapp
BACKGROUND/OBJECTIVE: We compared health-related quality of life (HRQoL) in patients randomized to escalated-therapy and those randomized to ablation for ventricular tachycardia in the VANISH trial. METHODS: HRQoL was assessed among VANISH patients at baseline and 3-, 6- and 12-month follow-up visits. Four validated instruments were used: the SF-36, the ICD Concerns questionnaire (ICDC), the Hospital Anxiety and Depression Scale (HADS), and the EuroQol five dimensions questionnaire (EQ-5D)...
January 9, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29315941/thromboembolic-prophylaxis-protocol-with-warfarin-after-radiofrequency-catheter-ablation-of-infarct-related-ventricular-tachycardia
#15
Konstantinos C Siontis, Sina Jamé, Ghaith Sharaf Dabbagh, Rakesh Latchamsetty, Krit Jongnarangsin, Fred Morady, Frank M Bogun
INTRODUCTION: Ablation in the left ventricle (LV) is associated with a risk of thromboembolism. There are limited data on the use of specific thromboembolic prophylaxis strategies post-ablation. We aimed to evaluate a thromboembolic prophylaxis protocol after ventricular tachycardia (VT) ablation. METHODS AND RESULTS: The index procedures of 217 patients undergoing ablation for infarct-related VT with open irrigated-tip catheters were included. Patients with large LV endocardial ablation area (> 3 cm between ablation lesions) were started on low-dose, slowly escalating unfractionated heparin (UFH) infusion 8 hours after access hemostasis, followed by 3 months of anticoagulation...
January 9, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29315657/dysautonomy-in-different-death-risk-groups-rassi-score-in-patients-with-chagas-heart-disease
#16
Catherine Masiel Merejo Peña, Michel Silva Reis, Basílio de Bragança Pereira, Emília Matos do Nascimento, Roberto Coury Pedrosa
BACKGROUND: It has been difficult to prove that the "catecholamine-induced cardiomyopathy" contributes to the mechanism of sudden cardiac death in Chagas heart disease. Also, it is almost impossible to rule out the possibility that is not involved in the process. More importantly, the vagal-cholinergic pathway in the ventricle plays a direct role in the prevention of the initiation of complex ventricular arrhythmias, including non-sustained ventricular tachycardia, ventricular fibrillation responsible for sudden death...
January 5, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29315367/sudden-death-in-patients-with-ebstein-anomaly
#17
Christine H Attenhofer Jost, Nicholas Y Tan, Abdalla Hassan, Emily R Vargas, David O Hodge, Joseph A Dearani, Heidi Connolly, Samuel J Asirvatham, Christopher J McLeod
Aims: Ventricular dysfunction or structural alteration of either ventricle is a well-established risk factor for sudden death (SD). Ebstein anomaly (EA) can present with both right and left heart abnormalities; however, predictors of SD have not been described. We therefore sought to characterize the incidence and risk factors of SD among a large cohort of patients with EA. Methods and results: All EA patients who underwent evaluation at a high-volume institution over a 4-decade period were retrospectively reviewed...
January 5, 2018: European Heart Journal
https://www.readbyqxmd.com/read/29314443/ryanodine-receptor-inhibition-by-dantrolene-effectively-suppresses-ventricular-arrhythmias-in-an-ex-vivo-model-of-long-qt-syndrome
#18
Gerrit Frommeyer, Julius Krawczyk, Christian Ellermann, Nils Bögeholz, Simon Kochhäuser, Dirk G Dechering, Michael Fehr, Lars Eckardt
AIMS: A significant antiarrhythmic potential of ryanodine receptor inhibition was reported in experimental studies. The aim of the present study was to assess potential antiarrhythmic effects of dantrolene in an experimental whole-heart model of drug-induced long-QT syndrome (LQTS). METHODS: In 12 isolated rabbit hearts long-QT-2-syndrome was simulated by infusion of erythromycin (300μM). 12 rabbit hearts were treated with veratridine (0.5μM) to mimic long-QT-3-syndrome...
January 4, 2018: Journal of Cardiovascular Electrophysiology
https://www.readbyqxmd.com/read/29313583/termination-of-ventricular-tachycardia-by-anti-tachycardia-pacing-an-uncommon-diagnosis-on-12-lead-surface-ecg
#19
Vaibhav M Dedhia
No abstract text is available yet for this article.
September 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/29312750/mitral-valve-prolapse-an-underestimated-cause-of-sudden-cardiac-death-a-current-review-of-the-literature
#20
REVIEW
Michael Spartalis, Eleni Tzatzaki, Eleftherios Spartalis, Antonios Athanasiou, Demetrios Moris, Christos Damaskos, Nikolaos Garmpis, Vassilis Voudris
Mitral valve prolapse (MVP) is a common valve abnormality in general population. Despite the general belief of a benign disorder, several articles since the 1980s report sudden cardiac death (SCD) in MVP patients, with a substantial percentage of asymptomatic young individuals. The problem is to detect those patients at increased risk and implement methods that are suitable to prevent cardiac arrest. This review investigates the correlation between MVP and SCD, the understanding of the pathophysiology, the strategies for detecting those at risk and treatment options...
December 2017: Journal of Thoracic Disease
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