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https://www.readbyqxmd.com/read/29684191/importance-of-beta-blocker-dose-in-prevention-of-ventricular-tachyarrhythmias-heart-failure-hospitalizations-and-death-in-primary-prevention-implantable-cardioverter-defibrillator-recipients-a-danish-nationwide-cohort-study
#1
A C Ruwald, G H Gislason, M Vinther, J B Johansen, J C Nielsen, B T Philbert, C Torp-Pedersen, S Riahi, C Jøns
Aims: There is a paucity of studies investigating a dose-dependent association between beta-blocker therapy and risk of outcome. In a nationwide cohort of primary prevention implantable cardioverter-defibrillator (ICD) patients, we aimed to investigate the dose-dependent association between beta-blocker therapy and risk of ventricular tachyarrhythmias (VT/VF), heart failure (HF) hospitalizations, and death. Methods and results: Information on ICD implantation, endpoints, comorbidities, beta-blocker usage, type, and dose were obtained through Danish nationwide registers...
April 19, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29684162/lifemap-towards-the-development-of-a-new-technology-in-sudden-cardiac-death-risk-stratification-for-clinical-use
#2
Ghulam André Ng, Amar Mistry, Xin Li, Fernando S Schlindwein, William B Nicolson
Sudden cardiac death (SCD) is a major cause of mortality presenting a significant unmet clinical need. Patients at risk of SCD are implanted with implantable cardioverter-defibrillators (ICDs) according to international guidelines based on clinical trial evidence. Implantable cardioverter-defibrillators are not inexpensive and not without problem in terms of inappropriate shocks and infection risk. Also, only a minority of patients implanted with the ICD ever use the device during its battery lifetime highlighting the fact that methods used for SCD risk stratification are inadequate...
April 19, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29682044/twiddler-s-syndrome-a-rare-hardware-complication-in-spinal-cord-stimulation
#3
Byung-Chul Son, Jin-Gyu Choi, Sang-Woo Ha
Twiddler's syndrome is an uncommon hardware complication involving the lead and pulse generators in cardiac pacemakers and defibrillators, deep brain stimulators, and vagal nerve stimulators. However, until very recently, it had not been reported in spinal cord stimulation (SCS). Considering the incidence of hardware complications of spinal cord stimulation, there may be an underreporting of Twiddler's syndrome due to lack of awareness. Two cases of Twiddler's syndrome as a hardware complication of SCS were identified between 2005 and 2015...
April 2018: Asian Journal of Neurosurgery
https://www.readbyqxmd.com/read/29680972/prophylactic-catheter-ablation-of-ventricular-tachycardia-in-ischemic-cardiomyopathy-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#4
REVIEW
Varunsiri Atti, Venkat Vuddanda, Mohit K Turagam, Praveen Vemula, Zubair Shah, Himakar Nagam, Srikanth Yandrapalli, Mohammad-Ali Jazayeri, Scott Koerber, Juan Viles Gonzalez, Andrea Natale, Luigi Di Biase, Dhanunjaya R Lakkireddy
BACKGROUND: Catheter ablation is proven to be an effective strategy for drug refractory ventricular tachycardia (VT) in ischemic cardiomyopathy. However, the appropriate timing of VT ablation and identifying the group of patients that may receive the greatest benefit remains uncertain. There is limited data on the effect on prophylactic catheter ablation (PCA) in the prevention of implantable cardioverter defibrillator (ICD) therapy, electrical storm, and mortality. METHODS: We performed a comprehensive literature search through November 1, 2017, for all eligible studies comparing PCA + ICD versus ICD only in eligible patients with ischemic cardiomyopathy...
April 21, 2018: Journal of Interventional Cardiac Electrophysiology: An International Journal of Arrhythmias and Pacing
https://www.readbyqxmd.com/read/29680351/the-prognostic-value-of-late-gadolinium-enhanced-cardiac-magnetic-resonance-imaging-in-nonischemic-dilated-cardiomyopathy-a-review-and-meta-analysis
#5
Marthe A J Becker, Jan H Cornel, Peter M van de Ven, Albert C van Rossum, Cornelis P Allaart, Tjeerd Germans
OBJECTIVES: This review and meta-analysis reviews the prognostic value of cardiac magnetic resonance (CMR) in nonischemic dilated cardiomyopathy (DCM). BACKGROUND: Late gadolinium-enhanced (LGE) CMR is a noninvasive method to determine the underlying cause of DCM and previous studies reported the prognostic value of the presence of LGE to identify patients at risk of major adverse cardiovascular events. METHODS: PubMed was searched for studies describing the prognostic implication of LGE in patients with DCM for the specified endpoints cardiovascular mortality, major ventricular arrhythmic events including appropriate implantable cardioverter-defibrillator therapy, rehospitalization for heart failure, and left ventricular reverse remodeling...
April 13, 2018: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/29678782/early-feasibility-of-hypoglossal-nerve-upper-airway-stimulator-in-patients-with-cardiac-implantable-electronic-devices-and-continuous-positive-airway-pressure-intolerant-severe-obstructive-sleep-apnea
#6
Valay Parikh, Erica Thaler, Masanari Kato, M Boyd Gillespie, Shaun Nguyen, Kirk Withrow, David Calhoun, Ryan Soose, Damien Stevens, Suzanne Stevens, Chris Larsen, Madhu Reddy, Dhanunjaya Lakkireddy
BACKGROUND: Implantable hypoglossal nerve upper airway stimulation (HNS) is a novel, FDA approved strategy for management of moderate to severe obstructive sleep apnea(OSA) patients with continuous positive airway pressure (CPAP) therapy intolerance or failure. Due to proximity of Cardiac Implantable Electronic Devices (CIED) and this stimulator, interaction between these devices is theoretically possible. OBJECTIVE: The purpose of this study was to assess interactions between implantable hypoglossal nerve upper airway stimulator device and cardiac implantable electronic devices...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29678779/experience-with-the-wearable-cardioverter-defibrillator-in-older-patients-results-from-the-prospective-registry-of-patients-using-the-wearable-cardioverter-defibrillator-wearit-ii-registry
#7
Usama A Daimee, Katherine Vermilye, Arthur J Moss, Ilan Goldenberg, Helmut U Klein, Scott McNitt, Wojciech Zareba, Valentina Kutyifa
BACKGROUND: Use of the wearable cardioverter-defibrillator (WCD) in older patients has not been described previously. OBJECTIVES: To assess WCD wear time, risk of arrhythmia events during WCD use, and implantable cardioverter-defibrillator (ICD) implantation rates following end of WCD use in patients with age ≥65 vs. <65 years. METHODS: We stratified 1,732 patients with ischemic and non-ischemic cardiomyopathies from the WEARIT-II registry into two sub-groups by age: ≥65 and <65 years...
April 17, 2018: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29678624/autonomic-cardiovascular-control-and-cardiac-arrhythmia-in-two-pregnant-women-with-hypertrophic-cardiomyopathy-insights-from-icd-monitoring
#8
Pietro Francia, Carmen Adduci, Beatrice Musumeci, Lorenzo Semprini, Francesca Palano, Luigi Zezza, Massimo Volpe, Camillo Autore
In women with hypertrophic cardiomyopathy (HCM), pregnancy prompts major changes in hemodynamic and cardiac autonomic function that may precipitate heart failure (HF) or increase the risk of cardiac arrhythmia. We report the clinical follow-up of two patients with non-obstructive HCM implanted with a cardioverter defibrillator (ICD) allowing for continuous analysis of heart rate (HR), heart rate variability (HRV) and cardiac arrhythmia throughout the entire course of pregnancy. Both patients experienced increased HR and decreased HRV from the early stages of pregnancy, which persisted until delivery...
April 17, 2018: Portuguese Journal of Cardiology: An Official Journal of the Portuguese Society of Cardiology
https://www.readbyqxmd.com/read/29678335/arrhythmic-risk-stratification-in-patients-with-idiopathic-dilated-cardiomyopathy
#9
Davide Stolfo, Nicole Ceschia, Massimo Zecchin, Antonio De Luca, Marco Gobbo, Giulia Barbati, Marta Gigli, Marco Masè, Bruno Pinamonti, Alberto Pivetta, Marco Merlo, Gianfranco Sinagra
Arrhythmic risk stratification in idiopathic dilated cardiomyopathy (IDC) remains a major concern. As the ventricles remodel in time, risk factors for arrhythmic death may change. A cohort of 710 patients with idiopathic dilated cardiomyopathy, without previous ventricular arrhythmias, was retrospectively studied to understand how risks vary in time. The primary end point was a composite of sudden cardiac death, ventricular fibrillation, sustained ventricular tachycardia, and appropriate implantable cardioverter-defibrillator interventions...
March 14, 2018: American Journal of Cardiology
https://www.readbyqxmd.com/read/29674365/protocol-of-a-multicenter-international-randomized-controlled-manikin-study-on-different-protocols-of-cardiopulmonary-resuscitation-for-laypeople-mani-cpr
#10
Enrico Baldi, Enrico Contri, Roman Burkart, Paola Borrelli, Ottavia Eleonora Ferraro, Michela Tonani, Amedeo Cutuli, Daniele Bertaia, Pasquale Iozzo, Caroline Tinguely, Daniel Lopez, Susi Boldarin, Claudio Deiuri, Sandrine Dénéréaz, Yves Dénéréaz, Michael Terrapon, Christian Tami, Cinzia Cereda, Alberto Somaschini, Stefano Cornara, Andrea Cortegiani
INTRODUCTION: Out-of-hospital cardiac arrest is one of the leading causes of death in industrialised countries. Survival depends on prompt identification of cardiac arrest and on the quality and timing of cardiopulmonary resuscitation (CPR) and defibrillation. For laypeople, there has been a growing interest on hands-only CPR, meaning continuous chest compression without interruption to perform ventilations. It has been demonstrated that intentional interruptions in hands-only CPR can increase its quality...
April 19, 2018: BMJ Open
https://www.readbyqxmd.com/read/29673607/impact-of-a-hybrid-decision-support-system-to-improve-the-adherence-to-implantable-cardioverter-defibrillator-therapy-guidelines-for-primary-prevention-of-sudden-cardiac-death
#11
Nicolás Vecchio, Diego Belardi, Mariano Benzadón, Leonardo Seoane, Gustavo Daquarti, Fernando Scazzuso
OBJECTIVES: Despite the well-documented benefit of implantable cardioverter defibrillator (ICD) in patients with severe left ventricular dysfunction, there is a large number of patients who had not been offered this therapy. The aim of this study is to evaluate the utility of a hybrid decision support system (hCDSS) to improve the adherence to indicate ICD therapy in our institution. METHODS: We conducted a retrospective, observational and single-center study. An hCDSS focused on patients with severe deterioration of the left ventricular function was implemented, creating a mandatory field containing the value of left ejection fraction and three options to choose: >35%, ≤ 35% or unknown...
June 2018: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/29672695/new-onset-of-phrenic-nerve-palsy-after-laser-assisted-transvenous-lead-extraction-a-single-centre-experience
#12
Tardu Özkartal, François Regoli, Giulio Conte, Maria Luce Caputo, Catherine Klersy, Tiziano Moccetti, Angelo Auricchio
Aims: Phrenic nerve palsy (PNP) after mechanical transvenous lead extraction (TLE) was recently described for the first time. We aimed to analyse our TLE database for the presence of PNP. Methods and results: All consecutive patients referred to our institution were included in this study. Every available post-procedural chest X-ray was compared to the routinely performed pre-procedural radiographs. A newly elevated hemidiaphragm ipsilateral to TLE was considered indicative of PNP...
April 16, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29672690/infections-and-associated-costs-following-cardiovascular-implantable-electronic-device-implantations-a-nationwide-cohort-study
#13
Nicolas Clémenty, Phuong Lien Carion, Lucie de Léotoing, Ludovic Lamarsalle, Fanny Wilquin-Bequet, Benedict Brown, Koen J P Verhees, Jérôme Fernandes, Jean-Claude Deharo
Aims: This study assessed the contemporary occurrence of cardiac device infections (CDIs) following implantation in French hospitals and estimated associated costs. Methods and Results: A retrospective analysis was conducted on the French National Hospital Database (PMSI). Patients with a record of de novo cardiac implantable electronic device (CIED) implantation or replacement interventions in France in 2012 were identified and followed until the end of 2015. Cardiac device infections (CDIs) were identified based on coding using the French classification for procedures [Classification Commune des Actes Médicaux (CCAM)] and International Classification of Diseases (ICD-10)...
April 17, 2018: Europace: European Pacing, Arrhythmias, and Cardiac Electrophysiology
https://www.readbyqxmd.com/read/29671882/electrocardiography-scar-quantification-correlates-with-scar-size-of-hypertrophic-cardiomyopathy-seen-by-multidetector-computed-tomography
#14
Tiago Costa Bignoto, Dalmo Antônio Ribeiro Moreira, Ricardo Garbe Habib, Edileide de Barros Correia, Ricardo Carneiro Amarante, Tannas Jatene, Mario Barbosa Guedes Nunes, Tiago Senra, Luiz Eduardo Mastrocolla
BACKGROUND: Hypertrophic cardiomyopathy (HCM), a genetically transmitted disease, is the most common genetic cardiovascular disease. Current strategies to stratify risk are expensive and concentrated in wealthy centers. Twelve-lead electrocardiography (ECG) is inexpensive and universally available and can be readily used for Selvester QRS scoring, which estimates scar size. This study aimed to establish the relation between ECG scar quantification and myocardial fibrosis (extent of myocardial delayed enhancement) in multidetector computed tomography (MDCT)...
April 19, 2018: Clinical Cardiology
https://www.readbyqxmd.com/read/29670762/rolling-refresher-simulation-improves-performance-and-retention-of-paediatric-intensive-care-unit-nurse-code-cart-management
#15
Marcy N Singleton, Kimberly F Allen, Zhongze Li, Kevin McNerney, Urs H Naber, Matthew S Braga
Introduction: Paediatric Intensive Care Unit Nurses (PICU RNs) manage the code cart during paediatric emergencies at the Children's Hospital at Dartmouth-Hitchcock. These are low -frequency, high-stakes events. Methods: An uncontrolled intervention study with 6-month follow-up. A collaboration of physician and nursing experts developed a rolling-refresher training programme consisting of five simulated scenarios, including 22 code cart skills, to establish nursing code cart competency...
April 2018: BMJ simulation & technology enhanced learning
https://www.readbyqxmd.com/read/29670531/beat-to-beat-variability-of-ventricular-action-potential-duration-oscillates-at-low-frequency-during-sympathetic-provocation-in-humans
#16
Bradley Porter, Stefan van Duijvenboden, Martin J Bishop, Michele Orini, Simon Claridge, Justin Gould, Benjamin J Sieniewicz, Baldeep Sidhu, Reza Razavi, Christopher A Rinaldi, Jaswinder S Gill, Peter Taggart
Background: The temporal pattern of ventricular repolarization is of critical importance in arrhythmogenesis. Enhanced beat-to-beat variability (BBV) of ventricular action potential duration (APD) is pro-arrhythmic and is increased during sympathetic provocation. Since sympathetic nerve activity characteristically exhibits burst patterning in the low frequency range, we hypothesized that physiologically enhanced sympathetic activity may not only increase BBV of left ventricular APD but also impose a low frequency oscillation which further increases repolarization instability in humans...
2018: Frontiers in Physiology
https://www.readbyqxmd.com/read/29668588/a-delayed-diagnosis-of-catecholaminergic-polymorphic-ventricular-tachycardia-with-a-mutant-of-ryr2-at-c-7580t-g-for-6-years-in-a-9-year-old-child
#17
Hongyu Duan, Yongyi Lu, Song Yan, Lina Qiao, Yimin Hua, Yifei Li, Kaiyu Zhou, Chuan Wang
RATIONALE: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare but potentially lethal inherited arrhythmia syndrome induced by adrenergic stress. Due to the atypical clinical manifestations in early age, limited recognition and experience of pediatric cardiologists, and low awareness of the significance of genetic diagnosis in some underdeveloped areas in China, a delayed or missed diagnosis of CPVT in children is common and concerning. PATIENT CONCERNS: A 9-year and 3-month male child with recurrent exercise-induced syncope accompanied by convulsion was initially misdiagnosed as epilepsy since the first manifestation at the age of 3 years...
April 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29667218/early-repolarization-is-involved-in-ventricular-fibrillation-in-patients-with-variant-angina
#18
Tetsuji Shinohara, Hidekazu Kondo, Akira Fukui, Hidefumi Akioka, Yasushi Teshima, Kunio Yufu, Mikiko Nakagawa, Naohiko Takahashi
BACKGROUND: Variant angina (VA) is caused by reversible coronary artery spasm, which is characterized by chest pain with ST segment elevations on a standard 12-lead electrocardiogram (ECG) at rest. VA attack often causes lethal ventricular arrhythmia. The early repolarization (ER) pattern is associated with ventricular fibrillation (VF). However, whether the ER pattern is involved in VF in patients with VA is not known. We investigated the association between the ER pattern and VF in patients with VA...
April 17, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29667046/radiotherapy-in-patients-with-cardiac-implantable-electronic-devices-clinical-and-dosimetric-aspects
#19
Giulia Riva, Ombretta Alessandro, Ruggero Spoto, Annamaria Ferrari, Cristina Garibaldi, Federica Cattani, Rosa Luraschi, Elena Rondi, Nicola Colombo, Fulvio Lorenzo Francesco Giovenzana, Carlo Maria Cipolla, Mikolaj Winnicki, Martina Persiani, Fabiana Castelluccia, Massimo Sarra Fiore, Roberto Orecchia, Barbara Alicja Jereczek-Fossa
As a result of aging, the number of patients with cardiac implantable electronic device (CIED) requiring radiotherapy (RT) continues to rise. The aim of this work was to evaluate RT-related malfunctions of CIED in a cohort of patients who underwent RT in our clinic from June 2010 to December 2016. We retrospectively analyzed 93 RT treatments in 63 patients with CIEDs. Patients were treated with 3D conformal RT, intensity-modulated RT and stereotactic RT. We collected clinical characteristics of cancer, models of CIEDs, total RT dose to tumor and radiation energy...
April 17, 2018: Medical Oncology
https://www.readbyqxmd.com/read/29663442/complexity-of-scar-and-ventricular-arrhythmias-in-dilated-cardiomyopathy-of-any-etiology-long-term-data-from-the-scarfear-cardiovascular-magnetic-resonance-predictors-of-appropriate-implantable-cardioverter-defibrillator-therapy-delivery-registry
#20
Stefano Pedretti, Sara Vargiu, Matteo Baroni, Santo Dellegrottaglie, Barbara Lanzarin, Alberto Roghi, Angela Milazzo, Giuseppina Quattrocchi, Maurizio Lunati, Patrizia Pedrotti
BACKGROUND: Late gadolinium enhancement (LGE) assessed with cardiovascular magnetic resonance (CMR) correlates with ventricular arrhythmias and survival in patients with structural heart disease. Whether some LGE characteristics may specifically improve prediction of arrhythmic outcomes is unknown. HYPOTHESIS: We sought to evaluate scar characteristics assessed with CMR to predict implantable cardioverter-defibrillator (ICD) interventions in dilated cardiomyopathy of different etiology...
April 17, 2018: Clinical Cardiology
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