keyword
MENU ▼
Read by QxMD icon Read
search

Direct current stimulation

keyword
https://www.readbyqxmd.com/read/29792531/the-expression-of-lysophosphatidic-acid-receptor-5-is-necessary-for-the-regulation-of-intestinal-na-h-exchanger-3-by-lysophosphatidic-acid-in-vivo
#1
Kayte A Jenkin, Peijian He, C Chris Yun
Lysophosphatidic acid (LPA) is a bioactive lipid molecule, which regulates a broad range of pathophysiological processes. Recent studies have demonstrated that LPA modulates electrolyte flux in the intestine and its potential as an anti-diarrheal agent has been suggested. Of six LPA receptors, LPA5 is highly expressed in the intestine. Recent studies by our group have demonstrated activation of Na+ /H+ exchanger 3 (NHE3) by LPA5 . However, much of what has been elucidated was achieved using colonic cell lines that were transfected to express LPA5 ...
May 24, 2018: American Journal of Physiology. Gastrointestinal and Liver Physiology
https://www.readbyqxmd.com/read/29792509/modulation-of-excitability-in-the-temporoparietal-junction-relieves-virtual-reality-sickness
#2
Naoyuki Takeuchi, Takayuki Mori, Yoshimi Suzukamo, Shin-Ichi Izumi
Virtual reality (VR) immersion often provokes subjective discomfort and postural instability, so called VR sickness. The neural mechanism of VR sickness is speculated to be related to visual-vestibular information mismatch and/or postural instability. However, the approaches proposed to relieve VR sickness through modulation of brain activity are poorly understood. Using transcranial direct current stimulation (tDCS), we aimed to investigate whether VR sickness could be relieved by the modulation of cortical excitability in the temporoparietal junction (TPJ), which is known to be involved in processing of both vestibular and visual information...
May 24, 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29791274/cathodal-tdcs-of-the-left-posterior-parietal-cortex-increases-proprioceptive-drift
#3
João Roberto Ventura de Oliveira, Marco Aurélio Romano-Silva, Herbert Ugrinowitsch, Tércio Apolinário-Souza, Lidiane Aparecida Fernandes, Juliana Otoni Parma, Guilherme Menezes Lage
In aiming movements the limb position drifts away from the defined target after some trials without visual feedback, a phenomenon defined as proprioceptive drift (PD). There are no studies investigating the association between the posterior parietal cortex (PPC) and PD in aiming movements. Therefore, cathodal and sham transcranial direct current stimulation (tDCS) were applied to the left PPC concomitantly with the performance of movements with or without vision. Cathodal tDCS applied without vision produced a higher level of PD and higher rates of drift accumulation while it decreased peak velocity and maintained the number of error corrections, not affecting movement amplitude...
May 23, 2018: Journal of Motor Behavior
https://www.readbyqxmd.com/read/29791142/reassessment-of-the-transport-mechanism-of-the-human-zinc-transporter-slc39a2
#4
Marie Christine Franz, Jonai Pujol-Gimenez, Nicolas Montalbetti, Miguel Fernandez-Tenorio, Timothy R DeGrado, Ernst Niggli, Michael F Romero, Matthias A Hediger
The human zinc transporter SLC39A2, also known as ZIP2, was shown to mediate zinc transport that could be inhibited at pH values below 7.0 and stimulated by HCO3-, suggesting a Zn2+/HCO3- cotransport mechanism (1). In contrast, recent experiments in our laboratory indicated that the functional activity of ZIP2 increases at acidic pH (2). The present study was therefore designed to reexamine the findings on the pH-dependence and to extend the functional characterization of ZIP2. Our current results show that ZIP2-mediated transport is modulated by extracellular pH, but independent of the H+ driving force...
May 23, 2018: Biochemistry
https://www.readbyqxmd.com/read/29789948/the-application-of-neuromuscular-electrical-stimulation-nmes-in-cancer-rehabilitation-current-prescription-pitfalls-and-future-directions
#5
Dominic O'Connor, Brian Caulfield
The plethora of treatment complications associated with cancer can be offset by regular exercise participation; however, adherence to current guidelines is poor, in particular in those unable or not allowed to participate in voluntary exercise due to their underlying disease. Alternative therapies such as neuromuscular electrical stimulation (NMES) are promising although previous results in cancer survivors have been equivocal. This is likely in response to methodological issues such as inappropriate NMES prescription...
May 22, 2018: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/29788768/short-term-impact-of-tdcs-over-the-right-inferior-frontal-cortex-on-impulsive-responses-in-a-go-no-go-task
#6
Salvatore Campanella, Elisa Schroder, Marie-Anne Vanderhasselt, Chris Baeken, Charles Kornreich, Paul Verbanck, Boris Burle
Inhibitory control, a process deeply studied in laboratory settings, refers to the ability to inhibit an action once it has been initiated. A common way to process data in such tasks is to take the mean response time (RT) and error rate per participant. However, such an analysis ignores the strong dependency between spontaneous RT variations and error rate. Conditional accuracy function (CAF) is of particular interest, as by plotting the probability of a response to be correct as a function of its latency, it provides a means for studying the strength of impulsive responses associated with a higher frequency of fast response errors...
May 1, 2018: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/29787486/a-random-dot-computer-video-game-improves-stereopsis
#7
Juan A Portela-Camino, Santiago Martín-González, Javier Ruiz-Alcocer, Igor Illarramendi-Mendicute, Rafaela Garrido-Mercado
SIGNIFICANCE: Currently, treatments for amblyopia are occlusion or penalization of the stronger fellow eye. Fewer than 30% of patients improve stereoacuity using these treatments. In order to improve these outcomes, this group proposes a treatment to stimulate the stereoacuity through perceptual learning in a game format for use at home. PURPOSE: The aim of this study was to determine whether perceptual learning with random dot stimuli (RDS) in the form of a computer video game improves stereopsis in patients with a history of amblyopia...
May 21, 2018: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/29785673/the-impact-of-transcranial-direct-current-stimulation-tdcs-on-bipolar-depression-mania-and-euthymia-a-systematic-review-of-preliminary-data
#8
Clément Dondé, Nicholas H Neufeld, Pierre A Geoffroy
The neurobiological basis of bipolar disorders (BD) has received increased attention and several brain regions and brain circuits have been correlated with clinical symptoms. These brain regions and circuits may represent targets for neuromodulation techniques such as transcranial Direct Current Stimulation (tDCS). We systematically reviewed the literature to explore the risks and benefits of tDCS in BD and examined all mood states. Following the PRISMA guidelines, a systematic literature search using several databases was performed from April 2002 to June 2017...
May 21, 2018: Psychiatric Quarterly
https://www.readbyqxmd.com/read/29784886/-legionella-pneumophila-is-directly-sensitive-to-2-deoxyglucose-phosphate-via-its-uhpc-transporter-but-is-indifferent-to-shifts-in-host-cell-glycolytic-metabolism
#9
Jordan V Price, Kallie Jiang, Abigail Galantowicz, Alana Freifeld, Russell E Vance
Toll-like receptor stimulation induces a pronounced shift to increased glycolytic metabolism in mammalian macrophages. We observed that bone marrow-derived macrophages (BMMs) increase glycolysis in response to infection with Legionella pneumophila ( L. pneumophila ), but the role of host macrophage glycolysis on intracellular L. pneumophila replication is not currently understood. Treatment with 2-deoxyglucose (2DG) blocks L. pneumophila replication in mammalian macrophages but has no effect on bacteria grown in broth...
May 21, 2018: Journal of Bacteriology
https://www.readbyqxmd.com/read/29784589/tolerability-and-blinding-of-4x1-high-definition-transcranial-direct-current-stimulation-hd-tdcs-at-two-and-three-milliamps
#10
Jaclyn Reckow, Annalise Rahman-Filipiak, Sarah Garcia, Stephen Schlaefflin, Oliver Calhoun, Alexandre F DaSilva, Marom Bikson, Benjamin M Hampstead
BACKGROUND: Transcranial direct current stimulation (tDCS) is an in-demand form of neuromodulation generally regarded as safe and well tolerated. However, few studies have examined the safety, tolerability, or blinding of High Definition (HD-) tDCS, especially in older adults and at stimulation intensities of 2 milliamps (mA) or greater. OBJECTIVE: We examined the rates of serious adverse events and common side effects to establish safety and tolerability, respectively, in HD-tDCS...
May 4, 2018: Brain Stimulation
https://www.readbyqxmd.com/read/29783893/the-effects-of-transcranial-direct-current-stimulation-tdcs-combined-with-group-exercise-treatment-in-subjects-with-chronic-low-back-pain-a-pilot-randomized-control-trial
#11
Sofia Straudi, Sergio Buja, Andrea Baroni, Claudia Pavarelli, Giulia Pranovi, Felipe Fregni, Nino Basaglia
OBJECTIVE: To test the efficacy of transcranial direct current stimulation (tDCS) in addition to group exercise on non-specific chronic low back pain. DESIGN: Double-blinded randomized control trial. SUBJECTS: Patients with non-specific chronic low back pain. METHODS: A total of 35 subjects were recruited and allocated to real- or sham-tDCS followed by a group exercise protocol. Each patient underwent five sessions of brain stimulation followed by 10 sessions of group exercise...
May 1, 2018: Clinical Rehabilitation
https://www.readbyqxmd.com/read/29782510/individual-differences-in-learning-correlate-with-modulation-of-brain-activity-induced-by-transcranial-direct-current-stimulation
#12
Brian Falcone, Atsushi Wada, Raja Parasuraman, Daniel E Callan
Transcranial direct current stimulation (tDCS) has been shown to enhance cognitive performance on a variety of tasks. It is hypothesized that tDCS enhances performance by affecting task related cortical excitability changes in networks underlying or connected to the site of stimulation facilitating long term potentiation. However, many recent studies have called into question the reliability and efficacy of tDCS to induce modulatory changes in brain activity. In this study, our goal is to investigate the individual differences in tDCS induced modulatory effects on brain activity related to the degree of enhancement in performance, providing insight into this lack of reliability...
2018: PloS One
https://www.readbyqxmd.com/read/29782471/new-approach-in-acne-therapy-a-specific-bacteriocin-activity-and-a-targeted-anti-il-8-property-in-just-1-probiotic-strain-the-l-salivarius-ls03
#13
Francesca Deidda, Angela Amoruso, Stefania Nicola, Teresa Graziano, Marco Pane, Luca Mogna
GOALS: The aim of this research was to assess the antibacterial activity of Lactobacillus salivarius LS03 (DSM 22776) against Propionibacterium acnes and its anti-inflammatory properties by inhibiting P. acnes-induced interleukin-8 (IL-8) release. BACKGROUND: Acne is the most common skin disease, causing significant psychosocial problems for those afflicted. Currently available agents for acne treatment, such as oral antibiotics, have limited use. Thus, development of novel agents to treat this disease is needed...
May 18, 2018: Journal of Clinical Gastroenterology
https://www.readbyqxmd.com/read/29780572/cognitive-training-and-transcranial-direct-current-stimulation-for-mild-cognitive-impairment-in-parkinson-s-disease-a-randomized-controlled-trial
#14
Blake J Lawrence, Natalie Gasson, Andrew R Johnson, Leon Booth, Andrea M Loftus
This study examined whether standard cognitive training, tailored cognitive training, transcranial direct current stimulation (tDCS), standard cognitive training + tDCS, or tailored cognitive training + tDCS improved cognitive function and functional outcomes in participants with PD and mild cognitive impairment (PD-MCI). Forty-two participants with PD-MCI were randomized to one of six groups: (1) standard cognitive training, (2) tailored cognitive training, (3) tDCS, (4) standard cognitive training + tDCS, (5) tailored cognitive training + tDCS, or (6) a control group...
2018: Parkinson's Disease
https://www.readbyqxmd.com/read/29780305/comparing-effects-of-transforming-growth-factor-%C3%AE-1-on-microglia-from-rat-and-mouse-transcriptional-profiles-and-potassium-channels
#15
Starlee Lively, Doris Lam, Raymond Wong, Lyanne C Schlichter
The cytokine, transforming growth factor β1 (TGFβ1), is up-regulated after central nervous system (CNS) injuries or diseases involving microglial activation, and it has been proposed as a therapeutic agent for treating neuroinflammation. Microglia can produce and respond to TGFβ1. While rats and mice are commonly used for studying neuroinflammation, very few reports directly compare them. Such studies are important for improving pre-clinical studies and furthering translational progress in developing therapeutic interventions...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29779818/fighting-obesity-non-pharmacological-interventions
#16
María Fernanda Higuera-Hernández, Elena Reyes-Cuapio, Marissa Gutiérrez-Mendoza, Nuno Barbosa Rocha, André Barciela Veras, Henning Budde, Johanna Jesse, Jaime Zaldívar-Rae, Carlos Blanco-Centurión, Sérgio Machado, Eric Murillo-Rodríguez
The abnormal or excessive fat accumulation that impairs health is one of the criteria that fulfills obesity. According to epidemiological data, obesity has become a worldwide public health problem that in turn would trigger additional pathologies such as cardiorespiratory dysfunctions, cancer, gastrointestinal disturbances, depression, sleep disorders, just to mention a few. Then, the search for a therapeutical intervention aimed to prevent and manage obesity has been the focus of study during the last years...
June 2018: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/29778264/hepatitis-c-virus-diagnosis-and-the-holy-grail
#17
REVIEW
Tanya L Applegate, Emmanuel Fajardo, Jilian A Sacks
The world has embraced the call for global elimination of hepatitis C virus by 2030. The unprecedented speed of therapeutic development and increased access to direct-acting antivirals has made elimination a possibility. We must screen hundreds of millions of people to diagnose and treat those currently infected. Global access to hepatitis C virus diagnostics will be a keystone to success. Key challenges must be overcome and systems optimized to ensure widespread access to existing diagnostics. Although promising technologies may soon transform the landscape, innovative strategies are needed to stimulate investment and accelerate the development of point-of-care hepatitis C virus diagnostics...
June 2018: Infectious Disease Clinics of North America
https://www.readbyqxmd.com/read/29773801/lrrc8-vrac-anion-channels-enhance-%C3%AE-cell-glucose-sensing-and-insulin-secretion
#18
Till Stuhlmann, Rosa Planells-Cases, Thomas J Jentsch
Glucose homeostasis depends critically on insulin that is secreted by pancreatic β-cells. Serum glucose, which is directly sensed by β-cells, stimulates depolarization- and Ca2+ -dependent exocytosis of insulin granules. Here we show that pancreatic islets prominently express LRRC8A and LRRC8D, subunits of volume-regulated VRAC anion channels. Hypotonicity- or glucose-induced β-cell swelling elicits canonical LRRC8A-dependent VRAC currents that depolarize β-cells to an extent that causes electrical excitation...
May 17, 2018: Nature Communications
https://www.readbyqxmd.com/read/29773509/the-role-of-the-inferior-frontal-gyrus-in-vicarious-social-touch-a-transcranial-direct-current-stimulation-tdcs-study
#19
Leehe Peled-Avron, Laura Glasner, Hila Z Gvirts, Simone G Shamay-Tsoory
The neural mechanisms facilitating the experience of vicarious social touch are largely unknown. The right inferior frontal gyrus (rIFG) has been suggested as part of a simulation observation-execution neural network that plays a key role in the perception of tactile stimuli. Considering that vicarious social touch involves vicarious sharing of emotions, we hypothesized that emotional empathy, i.e., the ability to feel what another individual is feeling, modulates the neural responses to vicarious touch. To examine the role of the rIFG in vicarious touch and its modulation by levels of emotional empathy, we used anodal transcranial direct current stimulation (tDCS) on forty participants who observed photos depicting social touch, nonsocial touch or no touch during tDCS or sham stimulation...
April 30, 2018: Developmental Cognitive Neuroscience
https://www.readbyqxmd.com/read/29770490/functional-magnetic-resonance-electrical-impedance-tomography-fmreit-sensitivity-analysis-using-an-active-bidomain-finite-element-model-of-neural-tissue
#20
Rosalind J Sadleir, Fanrui Fu, Munish Chauhan
PURPOSE: A direct method of imaging neural activity was simulated to determine typical signal sizes. METHODS: An active bidomain finite-element model was used to estimate approximate perturbations in MR phase data as a result of neural tissue activity, and when an external MR electrical impedance tomography imaging current was added to the region containing neural current sources. RESULTS: Modeling-predicted, activity-related conductivity changes should produce measurable differential phase signals in practical MR electrical impedance tomography experiments conducted at moderate resolution at noise levels typical of high field systems...
May 16, 2018: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
keyword
keyword
10917
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"