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https://www.readbyqxmd.com/read/29341878/concentrations-of-arsenic-and-lead-in-rice-oryza-sativa-l-in-iran-a-systematic-review-and-carcinogenic-risk-assessment
#1
Yadolah Fakhri, Geir Bjørklund, Anoushiravan Mohseni Bandpei, Salvatore Chirumbolo, Hassan Keramati, Rokhsane Hosseini Pouya, Anvar Asadi, Nazak Amanidaz, Mansour Sarafraz, Amir Sheikhmohammadi, Zahra Baninameh, Seyed Mohsen Mohseni, Maryam Sarkhosh, Seyed Mehdi Ghasemi
Exposure to heavy metals such as arsenic (As), lead (Pb), and cadmium (Cd) in either the short or the long term can cause cancers in humans. Dietary intake and consumption of rice (Oryza sativa L.) is increasing in Iran, and several studies on the concentration of heavy metals in rice have been carried out in this country in recent years. In this perspective, the main objective of the present study was to investigate, even via a meta-analysis of the existing literature, the presence of As and Pb in rice from many geographical areas in Iran, as well as to estimate the carcinogenic risk of these heavy metals in rice consumers...
January 13, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29340378/chemical-dynamics-simulations-of-cid-of-peptide-ions-comparisons-between-tik-h-2-and-tlk-h-2-fragmentation-dynamics-and-with-thermal-simulations
#2
Zahra Homayoon, Veronica Macaluso, Ana Martin-Somer, Maria Carolina Nicola Barbosa Muniz, Itamar Borges, William L Hase, Riccardo Spezia
Gas phase unimolecular fragmentation of the two model doubly protonated tripeptides threonine-isoleucine-lysine (TIK) and threonine-leucine-lysine (TLK) is studied using chemical dynamics simulations. Attention is focused on different aspects of collision induced dissociation (CID): fragmentation pathways, energy transfer, theoretical mass spectra, fragmentation mechanisms, and the possibility of distinguishing isoleucine (I) and leucine (L). Furthermore, discussion is given regarding the differences between single collision CID activation, which results from a localized impact between the ions and a colliding molecule N2, and previous thermal activation simulation results; Z...
January 17, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29340122/a-cross-sectional-study-of-glycemic-status-and-zinc-level-in-patients-with-beta-thalassemia-major
#3
Mohammad Ali Mashhadi, Zahra Sepehri, Zahra Heidari, Mahmoud Ali Kaykhaei, Aliyeh Sargazi, Farhad Kohan, Hanieh Heidari
Background: Endocrinopathies and diabetes mellitus are prevalent in patients with beta-thalassemia major Recently some studies demonstrate a link between low levels of serum zinc level and higher prevalence of diabetes. The aim of this study was to evaluate the glucose tolerance in patients suffered from beta-thalassemia major and determine the association of Homeostasis Model Assessment (HOMA) parameters with zinc status among these patients. Materials andMethods: In this cross sectional study, clinical data of patients who were suffered from thalassemia major, aged≥10 years were collected...
October 1, 2017: International Journal of Hematology-oncology and Stem Cell Research
https://www.readbyqxmd.com/read/29338972/hdl-c-apoa1-and-vldl-tg-as-biomarkers-for-the-carotid-plaque-presence-in-patients-with-metabolic-syndrome
#4
Meryem Abi-Ayad, Amine Abbou, Fatima Zahra Abi-Ayad, Omar Behadada, Mohamed Benyoucef
AIM: Hypercholesterolemia and hyper LDL-C are associated with the atherosclerosis (AS). The current study was performed to evaluate the implication of the others lipoproteins (HDL, LDL, VLDL) and apolipoproteins (ApoA1, ApoB100) with subclinical atherosclerosis (carotid plaque) in patients with metabolic syndrome (MetS) free from cardiovascular disease (CVD). METHODS: Prospective transversal study was conducted in patients with MetS free from cardiovascular disease (CVD)...
December 30, 2017: Diabetes & Metabolic Syndrome
https://www.readbyqxmd.com/read/29337918/polyacrylamide-ferrogels-with-magnetite-or-strontium-hexaferrite-next-step-in-the-development-of-soft-biomimetic-matter-for-biosensor-applications
#5
Alexander P Safronov, Ekaterina A Mikhnevich, Zahra Lotfollahi, Felix A Blyakhman, Tatyana F Sklyar, Aitor Larrañaga Varga, Anatoly I Medvedev, Sergio Fernández Armas, Galina V Kurlyandskaya
Magnetic biosensors are an important part of biomedical applications of magnetic materials. As the living tissue is basically a "soft matter." this study addresses the development of ferrogels (FG) with micron sized magnetic particles of magnetite and strontium hexaferrite mimicking the living tissue. The basic composition of the FG comprised the polymeric network of polyacrylamide, synthesized by free radical polymerization of monomeric acrylamide (AAm) in water solution at three levels of concentration (1...
January 16, 2018: Sensors
https://www.readbyqxmd.com/read/29337228/monitoring-the-prevalence-of-genetically-modified-gm-maize-in-iran-food-products
#6
Motahreh Sadat Hosseini, Gilda Eslami, Bahador Hajimohammadi, Hossein Fallahzadeh, Zahra Derakhshan, Gea Oliveri Conti, Margherita Ferrante
Maize, the second most important genetically modified (GM) crop, and an ingredient in many foodstuffs worldwide. Regulations for both the labeling and the traceability of GMOs in feed chains are coming into force worldwide. To provide consumer's information, labelling for food products containing more than 0.9% of GM material is demanded by the actual EU legislation. Analysis of foods is then essential to detect and quantify GM maize material and verify the compliance with labelling information. For this purpose, reliable and accurate detection methods are a necessity...
January 11, 2018: Food and Chemical Toxicology
https://www.readbyqxmd.com/read/29336898/effect-of-transcranial-direct-current-stimulation-on-short-term-and-long-term-treatment-of-chronic-tinnitus
#7
Hamidreza Abtahi, Ahmadreza Okhovvat, Somaiie Heidari, Azar Gharagazarloo, Motahare Mirdamadi, Mohammad Hossein Nilforoush, Hossein Ghazavi
OBJECTIVE: This study was conducted to investigate the effectiveness of anodal and cathodal methods in reducing the intensity of tinnitus and to compare them with the control. METHODOLOGY: This randomized double-blind clinical trial with case and control groups was conducted in Al-Zahra Hospital in Isfahan between 2015 and 2016. In this trial, 51 patients with tinnitus, for at least one year, were selected among those outpatients visiting the throat, nose and ear clinic within this period...
January 6, 2018: American Journal of Otolaryngology
https://www.readbyqxmd.com/read/29336265/efficacy-of-aloe-vera-plantago-major-gel-in-diabetic-foot-ulcer-a-randomized-double-blind-clinical-trial
#8
Younes Najafian, Zahra Mazloum Khorasani, Mona Najaf Najafi, Shokouhsadat Hamedi, Marjan Mahjour, Zohre Feyzabadi
BACKGROUND: Diabetic foot ulcer (DFU) is one of the most common complications of diabetic patients. Mostly, non-healing DFU leads to infection, gangrene, amputation and even death. High costs and poor healing of the wounds need a new treatment such as alternative medicine. So, the aim of this study was to evaluate the efficacy of Aloe vera/ Plantago major gel (Plantavera gel) in healing of DFU. METHODS: Forty patients with DFU enrolled in a double-blind randomized clinical trial...
January 14, 2018: Current Drug Discovery Technologies
https://www.readbyqxmd.com/read/29335541/modulation-of-uvb-induced-carcinogenesis-by-activation-of-alternative-dna-repair-pathways
#9
Yan Sha, Vladimir Vartanian, Nichole Owen, Stephanie J Mengden Koon, Marcus J Calkins, Courtney S Thompson, Zahra Mirafzali, Sara Mir, Lisa E Goldsmith, Huaping He, Chun Luo, Scott M Brown, Paul W Doetsch, Andy Kaempf, Jeong Y Lim, Amanda K McCullough, R Stephen Lloyd
The molecular basis for ultraviolet (UV) light-induced nonmelanoma and melanoma skin cancers centers on cumulative genomic instability caused by inefficient DNA repair of dipyrimidine photoproducts. Inefficient DNA repair and subsequent translesion replication past these DNA lesions generate distinct molecular signatures of tandem CC to TT and C to T transitions at dipyrimidine sites. Since previous efforts to develop experimental strategies to enhance the repair capacity of basal keratinocytes have been limited, we have engineered the N-terminally truncated form (Δ228) UV endonuclease (UVDE) from Schizosaccharomyces pombe to include a TAT cell-penetrating peptide sequence with or without a nuclear localization signal (NLS): UVDE-TAT and UVDE-NLS-TAT...
January 15, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29335206/synthesis-and-biological-evaluation-of-4-amino-5-cinnamoylthiazoles-as-chalcone-like-anticancer-agents
#10
Adileh Ayati, Rezvan Esmaeili, Setareh Moghimi, Tayebeh Oghabi Bakhshaiesh, Zahra Eslami-S, Keivan Majidzadeh-A, Maliheh Safavi, Saeed Emami, Alireza Foroumadi
A series of 4-amino-5-cinnamoylthiazoles 3a-p were designed and synthesized as chalcone-like anticancer agents. The synthesized derivatives 3a-p were evaluated for their in vitro antiproliferative activities against three different human cancer cell lines including MCF-7, HepG2 and SW480. Most of compounds could significantly prevent proliferation of tested cell lines. In particular, the pyrrolidine derivative 3e namely (E)-1-(4-amino-2-(pyrrolidin-1-yl)thiazol-5-yl)-3-(2,4-dichlorophenyl)prop-2-en-1-one showed promising activity, especially against HepG2 cells (IC50 = 10...
January 6, 2018: European Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29334847/patient-and-family-psychoeducation-service-development-and-implementation-in-a-center-in-iran
#11
Zahra Mirsepassi, Maryam Tabatabaee, Vandad Sharifi, Yasaman Mottaghipour
BACKGROUND: Family and patient psychoeducation have demonstrated significant improvement in clinical and social outcomes for patients suffering from severe mental disorders and their families. However, these evidence-based practices are not widely implemented at service delivery level and into routine clinical practice, especially in less developed countries. AIM: The aim of this article is to report the processes of development and implementation of a psychoeducational service for patients with severe mental illnesses and their families in Iran...
February 2018: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/29334209/comparison-of-the-effects-of-vitrification-on-gene-expression-of-mature-mouse-oocytes-using-cryotop-and-open-pulled-straw
#12
Fardin Amidi, Zahra Khodabandeh, Mohamad Hossain Nori Mogahi
Background: Oocyte cryopreservation is an essential part of the assisted reproductive technology (ART), which was recently introduced into clinical practice. This study aimed to evaluate the effects of two vitrification systems-Cryotop and Open Pulled Straw (OPS)-on mature oocytes gene expressions. MATERIALS AND METHODS: In this experimental study, the survival rate of metaphase II (MII) mouse oocytes were assessed after cryopreservation by vitrification via i. OPS or ii...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29334206/decreased-expression-of-arginine-phenylalanine-amide-related-peptide-3-gene-in-dorsomedial-hypothalamic-nucleus-of-constant-light-exposure-model-of-polycystic-ovarian-syndrome
#13
Zahra Shaaban, Mohammad Reza Jafarzadeh Shirazi, Mohammad Hossein Nooranizadeh, Amin Tamadon, Farhad Rahmanifar, Somayeh Ahmadloo, Amin Ramezani, Mohammad Javad Zamiri, Iman Razeghian Jahromi, Fatemeh Sabet Sarvestani, Omid Koohi Hosseinabadi
Background: An abnormality in pulse amplitude and frequency of gonadotropin releasing hormone (GnRH) secretion is the most characteristics of polycystic ovarian syndrome (PCOS). On the other hand, arginine-phenylalanine-amide (RFamide)-related peptide-3 (RFRP3) inhibits the secretion of GnRH in mammalian hypothalamus. The current study performed in order to investigate the expression of RFRP3 mRNA in the dorsomedial hypothalamic nucleus (DMH) after the induction of PCOS in a rat model of constant light exposure, and the possible role of parity on occurrence of PCOS...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29334200/comparative-effectiveness-of-antidepressant-medication-versus-psychological-intervention-on-depression-symptoms-in-women-with-infertility-and-sexual-dysfunction
#14
Hajar Pasha, Zahra Basirat, Mahbobeh Faramarzi, Farzan Kheirkhah
Background: Fertility loss is considered as a challenging experience. This study was conducted to compare the effectiveness of antidepressant medication and psychological intervention on depression symptoms in women with infertility and sexual dysfunctions (SD). MATERIALS AND METHODS: This randomized, controlled clinical trial study was completed from December 2014 to June 2015 in Babol, Iran. Of the 485 participants, 93 were randomly assigned in a 1:1:1 ratio to psychosexual therapy (PST), bupropion extended-release (BUP ER) at a dose of 150 mg/d, and control (no intervention) groups...
April 2018: International Journal of Fertility & Sterility
https://www.readbyqxmd.com/read/29333903/the-first-report-of-relative-incidence-of-inherited-white-matter-disorders-in-an-asian-country-based-on-an-iranian-bioregistry-system
#15
Mahmoud Reza Ashrafi, Zahra Rezaei, Morteza Heidari, Sedigheh Nikbakht, Reza Azizi Malamiri, Mahmoud Mohammady, Gholam Reza Zamani, Reza Shervin Badv, Parastoo Rostami, Mojtaba Movahedinia, Mostafa Qorbani, Man Amanat, Ali Reza Tavasoli
Childhood leukodystrophies are a fast-growing field of pediatric neurology practice. Epidemiologic studies on the incidence of these disorders in children show different results. This is the first report of childhood leukodystrophies incidence from Iran. The enrolled patients were recruited from the neurometabolic bioregistry system that was organized in 2010 in the Children's Medical Center, Tehran, Iran. Herein is reported the incidence rate of leukodystrophies in those patients who were residents of 2 big popular provinces near Iran's capital city Tehran, with an average child population of 2 988 800 children...
January 1, 2018: Journal of Child Neurology
https://www.readbyqxmd.com/read/29333377/dietary-l-arginine-intakes-and-the-risk-of-metabolic-syndrome-a-6-year-follow-up-in-tehran-lipid-and-glucose-study
#16
Parvin Mirmiran, Sajjad Khalili Moghadam, Zahra Bahadoran, Asghar Ghasemi, Fereidoun Azizi
This study was conducted to investigate whether regular dietary intake of L-arginine could affect the occurrence of metabolic syndrome (MetS). Eligible adult men and women (n=1,237), who participated in the Tehran Lipid and Glucose Study, were followed for a median of 6.3 years. Dietary intakes of L-arginine and serum nitrate and nitrite (NOx) concentration were assessed at baseline (2006~2008), and demographics, anthropometrics, and biochemical variables were evaluated at baseline and follow-up examinations...
December 2017: Preventive Nutrition and Food Science
https://www.readbyqxmd.com/read/29332755/investigating-the-anticipatory-postural-adjustment-phase-of-gait-initiation-in-different-directions-in-chronic-ankle-instability-patients
#17
Zahra Ebrahimabadi, Sedigheh Sadat Naimi, Abbas Rahimi, Heydar Sadeghi, Seyed Majid Hosseini, Alireza Akbarzadeh Baghban, Syed Asadullah Arslan
OBJECTIVE: The main objective of the present study was to analyze how supra spinal motor control mechanisms are altered in different directions during anticipatory postural phase of gait initiation in chronic ankle instability patients. It seems that supra spinal pathways modulate anticipatory postural adjustment phase of gait initiation. Yet, there is a dearth of research on the effect of chronic ankle instability on the anticipatory postural adjustment phase of gait initiation in different directions...
January 2018: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/29332284/measurement-of-hypersensitive-cell-death-triggered-by-avirulent-bacterial-pathogens-in-arabidopsis
#18
Zahra Imanifard, Elodie Vandelle, Diana Bellin
The hypersensitive response is one of the most powerful and complex defense reactions to survive to pathogen attacks during an incompatible plant-pathogen interaction. Local programmed cell death accompanies the hypersensitive response at the site of infection to prevent pathogen growth and spread. A precise quantitative assessment of this form of programmed cell death is essential to unravel the genetic and molecular mechanisms underlying the process. Here, we first describe the optimization of a Trypan Blue staining protocol for quantitatively measuring the HR-cell death in Arabidopsis...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29332097/is-the-atopy-patch-test-reliable-in-the-evaluation-of-food-allergy-related-atopic-dermatitis
#19
Mahboubeh Mansouri, Elham Rafiee, Sepideh Darougar, Mehrnaz Mesdaghi, Zahra Chavoshzadeh
BACKGROUND: Aeroallergens and food allergens are found to be relevant in atopic dermatitis. The atopy patch test (APT) can help to detect food allergies in children with atopic dermatitis. This study evaluates if the APT is a valuable tool in the diagnostic workup of children with food allergy-related atopic dermatitis. METHODS: 42 children between 6 months and 12 years of age were selected at the Mofid Children Hospital. Atopic dermatitis was diagnosed, and the severity of the disease was determined...
January 13, 2018: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/29332033/effect-of-dual-tasking-on-anticipatory-and-compensatory-postural-adjustments-in-response-to-external-perturbations-in-individuals-with-nonspecific-chronic-low-back-pain-electromyographic-analysis
#20
Ladan Hemmati, Soraya Piroozi, Zahra Rojhani-Shirazi
BACKGROUND: In patients with chronic low back pain (CLBP), postural control is a demanding task in terms of attention. Although the attentional demands of postural control have been investigated in these patients, the attentional demands of postural recovery during dual task performance have not been evaluated in patients with nonspecific CLBP. OBJECTIVE: To investigate the effect of dual tasking on anticipatory and compensatory postural adjustments in response to an external perturbation in patients with nonspecific CLBP...
December 29, 2017: Journal of Back and Musculoskeletal Rehabilitation
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