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L M Mena Bares, E Carmona Asenjo, M V García Sánchez, E Moreno Ortega, F R Maza Muret, M V Guiote Moreno, A M Santos Bueno, E Iglesias Flores, J M Benítez Cantero, J A Vallejo Casas
Chronic diarrhoea is a common entity in daily clinical practice and it leads to a loss in these patients quality of life. It may be the main symptom of multiple ethiologies including bile acid malabsorption (BAM) which has a comparable prevalence to celiac disease. The BAM results from imbalances in the homeostasis of bile acids in the enterohepatic circulation. It can be a consequence of ileal disease or ileal dysfunction (BAM type i), it can be considered idiopathic or primary (BAM type ii) or associated with other gastrointestinal entities (BAM type iii)...
October 17, 2016: Revista Española de Medicina Nuclear e Imagen Molecular
Rosario Lucas López, María José Grande Burgos, Antonio Gálvez, Rubén Pérez Pulido
Inflammatory bowel disease (IBD) includes a spectrum of diseases from ulcerative colitis (UC) to Crohn's disease (CD). Many studies have addressed the changes in the microbiota of individuals affected by UC and CD. A decrease in biodiversity and depletion of the phyla Bacteroidetes and Firmicutes has been reported, among others. Changes in microbial composition also result in changes in the metabolites generated in the gut from microbial activity that may involve the amount of butyrate and other metabolites such as H2 S being produced...
October 5, 2016: APMIS: Acta Pathologica, Microbiologica, et Immunologica Scandinavica
Lluis Guirao Cano
OBJECTIVE: Following a transfemoral (TF) amputation, the ability to walk with a prosthesis is the main objective of rehabilitation. The achieved speed of walking is considered a determining factor in the amputee's perception of quality of life. This experimental before-after study evaluates the walking abilities and improvement of important parameters such as gait, walking speed, pain and hours of prosthesis use in transfemoral amputees after placing a novel femoral implant that permits distal weight bearing of the residuum within a socket, adapted for distal load bearing...
September 2016: Annals of Physical and Rehabilitation Medicine
Catalina Ibarra, Valentina Herrera, Edith Pérez de Arce, Luis Carlos Gil, Ana María Madrid, Lucía Valenzuela, Caroll J Beltrán
Irritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract characterised by multi-factorial aetiology. In IBS physiopathology are involved diverse factors between them biological, psychosocial, and environmental components which affect the immune activation status of gut mucosa. Among these factors is recognized the intestinal parasitosis. Post-infection IBS (PI-IBS) is recognised as a subgroup of functional disorders whose symptoms onset appear after a symptomatic intestinal infection caused by microbial agents...
June 2016: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
D Lauritano, L Lo Muzio, R M Gaudio, L Lo Russo, D Mucchi, G M Nardi, L Scapoli
Periodontal disease (PD) is one of the prevalent diseases in the adult population. The ethiology of PD has never been completely understood, however, loss of balance between the host immune system and the microbial virulence of PD pathogens may be considered the trigger of PD. In fact, the immune system, activated by microbiological agents, attacks the host and not the biofilm bacteria, causing the destruction of periodontal tissue, alveolar bone and loss of teeth. Parasites may play an important role in the pathology of PD...
April 2016: Journal of Biological Regulators and Homeostatic Agents
Emanuele A Alves, Pedro Brandão, Teresa Magalhães, Félix Carvalho, Ricardo J Dinis-Oliveira
Fatal intoxications are a topic of great relevance in today's society. This study retrospectively reviews fatal intoxication cases autopsied at the northern forensic medicine services of Portugal, between 2001 and 2013. For this purpose, we analyzed postmortem forensic medical reports with positive results for the presence of xenobiotics. A total of 27,778 autopsy reports were analyzed, of which 1,269 cases fulfilled the selection criteria, representing 4.6% of total number of individuals autopsied during the period under analysis...
July 24, 2016: Current Drug Safety
V G Akimkin, A A Kalmykov, R M Aminev, V S Polyakov, S V Artebyakin
The authors defined epidemiological efficacy and safety of the use of bacteriophages(streptococcal, staphylococcal, piobakferiophage multipartial) and bitsillin-5 to reduce tonsillitis morbidityand other respiratory diseases with bacterial etiology in groups of servicemen during their formationagainst increase of seasonal morbidity. The results of the use of these preventive agents were evaluatedby a comparative analysis of this disease in experimental and control groups. In total 510 healthy conscriptswere involved into the study...
February 2016: Voenno-medit︠s︡inskiĭ Zhurnal
Emmanuel Coronel M, Martín Coronel C
In this review we show you all the advances in ethiology, epidemiology, phisiopatology, natural history, clinic aspects, treatment and complications of non alcoholic steatohepatitis.
January 2016: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
Károly Acsai, Balázs Ördög, András Varró, Péter P Nánási
Abnormal Ca(2+)homeostasis is often associated with chronic cardiovascular diseases, such as hypertension, heart failure or cardiac arrhythmias, and typically contributes to the basic ethiology of the disease. Pharmacological targeting of cardiac Ca(2+)handling has great therapeutic potential offering invaluable options for the prevention, slowing down the progression or suppression of the harmful outcomes like life threatening cardiac arrhythmias. In this review we outline the existing knowledge on the involvement of malfunction of the ryanodine receptor and the Na(+)-Ca(2+)exchanger in disturbances of Ca(2+)homeostasis and discuss important proof of concept pharmacological studies targeting these mechanisms in context of hypertension, heart failure, atrial fibrillation and ventricular arrhythmias...
May 15, 2016: European Journal of Pharmacology
Ali Oner, Alper Koksal, Hakan Sofu, Umit S Aykut, Timur Yıldırım, Mehmet A Kaygusuz
OBJECTIVE: The main purpose of the present study was to determine the prevalence of FAI among patients who underwent total hip arthroplasty (THA) with the diagnosis of end-stage osteoarthritis (OA) of the hip joint in a tertiary referral centre. DESIGN: A retrospective search of the institutional archive database for patients who had undergone THA between the years 2005 and 2010 was conducted with the analysis of the recorded radiographic images. A total of 1,004 patients including 690 (68...
March 2016: Hip International: the Journal of Clinical and Experimental Research on Hip Pathology and Therapy
S Kovachev, A Ganovska, M Stoyanova
The probiotics are live microorganisms which embedded in adequate quantities have a healthy influence on the recipient. The current local probiotics get on medical practice at the beginning of the last decade and quickly become part of the current therapy of vaginal disbacteriosis and infections. A lot of studies show their microbiological and clinic effectiveness in prevention and treatment of the most met vaginal pathogens, usually together with on after pathogenetic or ethiological treatment. Slow release probiotics are the newest generation of probiotic products...
2015: Akusherstvo i Ginekologii︠a︡
Jonathan Esteban-Sánchez, Almudena Rueda-Marcos, Ricardo Sanz-Fernández, Eduardo Martín-Sanz
INTRODUCTION: The presentation of a down-beating nystagmus force to discard vascular pathology of brain and cervical joint with magnetic resonance imagine (MRI). Recent studies support the low profitability of this study and is subjected that this oculomotor sign has a peripheral origin especially when the patient has a benign paroxysmal positional vertigo (BPPV) with affection of the superior semicircular canal. AIM: To evidence the profitability of MRI in a population of patients with positional down-beating nystagmus...
February 1, 2016: Revista de Neurologia
Ozan Alper Alkoç, Ahmet Songur, Olcay Eser, Muhsin Toktas, Yücel Gönül, Ertap Esi, Alpay Haktanir
OBJECTIVE: In this study, we aimed to investigate the underlying ethiological factors in chiari malformation (CM) type-I (CMI) via performing volumetric and morphometric length-angle measurements. METHODS: A total of 66 individuals [33 patients (20-65 years) with CMI and 33 control subjects] were included in this study. In sagittal MR images, tonsillar herniation length and concurrent anomalies were evaluated. Supratentorial, infratentorial, and total intracranial volumes were measured using Cavalieri method...
November 2015: Journal of Korean Neurosurgical Society
Hugo Valdivia-Olarte, David Requena, Manuel Ramirez, Luis E Saravia, Ray Izquierdo, Francesca Falconi-Agapito, Milagros Zavaleta, Iván Best, Manolo Fernández-Díaz, Mirko Zimic
Fowl adenoviruses (FAdVs) are the ethiologic agents of multiple pathologies in chicken. There are five different species of FAdVs grouped as FAdV-A, FAdV-B, FAdV-C, FAdV-D, and FAdV-E. It is of interest to develop immunodiagnostics and vaccine candidate for Peruvian FAdV-C in chicken infection using MHC restricted short peptide candidates. We sequenced the complete genome of one FAdV strain isolated from a chicken of a local farm. A total of 44 protein coding genes were identified in each genome. We sequenced twelve Cobb chicken MHC alleles from animals of different farms in the central coast of Peru, and subsequently determined three optimal human MHC-I and four optimal human MHC-II substitute alleles for MHC-peptide prediction...
2015: Bioinformation
E A Gayfutdinov, V A Rudnov, V A Bagin
GOAL: study of special aspects in system inflammatory reaction caused by nosocomial bacteremia in dependence of the pathogen Gram-origin. The study included 85 patients with nosocomial bacteremia in ICU from 2010 till 2012. The main inclusion criteria was bacteria identification in blood, which was taken more than 48 hours from arrival to ICU within the appearance of system inflammatory response signs. Key options for clinical rating of system inflammatory response was dynamic of patients condition according APACHE II, SOFA, SAPS-III/PIRO, Pitt scales and its correlation with durations of mechanical ventilation, length of staying in ICU, total hospital period and outcome...
July 2015: Anesteziologiia i Reanimatologiia
Dídac Sotorra-Figuerola, Nieves Almendros-Marqués, Antonio-Jesús Espana-Tost, Eduard Valmaseda-Castellón, Cosme Gay-Escoda
UNLABELLED: Salivary gland choristoma (SGCh) is defined as the presence of normal salivary tissue in an abnormal location. It is a rare entity in oral and maxillofacial region and its ethiology is unknown. The typical presentation of salivary gland heterotopia is an asymptomatic mass that may or may not produce saliva. Some examples of ectopic salivary tissue in the pituitary gland, in the lymph nodes, in the middle ear, in the neck, in the jaw, in the thyroid gland, in the mediastinum and in the rectum have been documented in literature...
October 2015: Journal of Clinical and Experimental Dentistry
N Mamuchishvili, T Kuchuloria, I Mchedlishvili, P Imnadze, D Mirzashvili
Investigation of leptospirosis was initiated in 1950s, when the first cases in humans were detected in Gudauta rayon. Serology test confirmed the diagnose. High level of antibodies to serogroup Pomona was revealed in all cases. Later on the infection encountered as sporadic cases, the exception was 1986, when a large outbreak was reported in Sukhumi. At present leptospirosis is widely spread in the country, especially in Ajara region, where indicators of morbidity recently reached 11.4 per 100 thousand population...
July 2015: Georgian Medical News
Georg Gassmann, Wolfgang H Arnold
There is no doubt that the main reason for an internal grauloma is a traumatic event. The trauma may be physical or chemical as in the case of caries or coronal pulpectomy. In most of the cases it is diagnosed by hazard or, when in case of fracture or mobility, extraction is the only therapy to be performed. If diagnosed in time root canal treatment may be adequate.In the presented case no single specific event could be determined being the cause of this large internal granuloma extending from the coronal third of the root canal to the whole crown just leaving an eggshell of enamel that fractured and mimicked mobility of the whole tooth to the patient finally causing him to attend the clinic...
2015: Head & Face Medicine
Rosaline Rocha Lunardi, Letícia Pinho Gomes, Thaís Peres Câmara, Wagner Welber Arrais-Silva
Triatoma williami is naturally infected by Trypanosoma cruzi, the ethiological agent of Chagas disease, the most significant cause of morbidity and mortality in South and Central America.The possibility of domiciliation of T. williami increases the risk of human T. cruzi vetorial transmission. Despite this, there is a lack of data demonstrating the bionomic aspects, the vectorial competence or the natural ecotope and the wild hosts of T. williami. This study describes for the first time the life cycle of T...
September 2015: Acta Tropica
Lorete Maria da Silva Kotze, Renato Mitsunori Nisihara, Sandra Beatriz Marion, Murilo Franco Cavassani, Paulo Gustavo Kotze
BACKGROUND: Determination of fecal calprotectin can provide an important guidance for the physician, also in primary care, in the differential diagnosis of gastrointestinal disorders, meanly between inflammatory bowel diseases and irritable bowel syndrome. Objectives The aims of the present study were to prospectively investigate, in Brazilian adults with gastrointestinal complaints, the value of fecal calprotectin as a biomarker for the differential diagnosis between functional and organic disorders and to correlate the concentrations with the activity of inflammatory bowel diseases...
January 2015: Arquivos de Gastroenterologia
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