Kartik K Venkatesh, Sadiya S Khan, Lynn M Yee, Jiqiang Wu, Rebecca McNeil, Philip Greenland, Judith H Chung, Lisa D Levine, Hyagriv N Simhan, Janet Catov, Christina Scifres, Uma M Reddy, Victoria L Pemberton, George Saade, C Noel Bairey Merz, William A Grobman
OBJECTIVE: To determine whether adverse pregnancy outcomes are associated with a higher predicted 30-year risk of atherosclerotic cardiovascular disease (CVD; ie, coronary artery disease or stroke). METHODS: This was a secondary analysis of the prospective Nulliparous Pregnancy Outcomes Study-Monitoring Mothers-to-Be Heart Health Study longitudinal cohort. The exposures were adverse pregnancy outcomes during the first pregnancy (ie, gestational diabetes mellitus [GDM], hypertensive disorder of pregnancy, preterm birth, and small- and large-for-gestational-age [SGA, LGA] birth weight) modeled individually and secondarily as the cumulative number of adverse pregnancy outcomes (ie, none, one, two or more)...
April 5, 2024: Obstetrics and Gynecology