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https://www.readbyqxmd.com/read/28531946/the-role-of-mobilisation-and-delivery-processes-on-contrasting-dissolved-nitrogen-and-phosphorus-exports-in-groundwater-fed-catchments
#1
Rémi Dupas, Per-Erik Mellander, Chantal Gascuel-Odoux, Ophélie Fovet, Eoin B McAleer, Noeleen T McDonald, Mairead Shore, Phil Jordan
Diffuse transfer of nitrogen (N) and phosphorus (P) in agricultural catchments is controlled by the mobilisation of sources and their delivery to receiving waters. While plot scale experiments have focused on mobilisation processes, many catchment scale studies have hitherto concentrated on the controls of dominant flow pathways on nutrient delivery. To place mobilisation and delivery at a catchment scale, this study investigated their relative influence on contrasting nitrate-N and soluble P concentrations and N:P ratios in two shallow groundwater fed catchments with different land use (grassland and arable) on the Atlantic seaboard of Europe...
May 17, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28531940/contusional-cerebellar-hemorrhage-related-to-placement-in-the-protrusion-position-after-atlantoaxial-fusion
#2
Yoshinari Miyaoka, Mikinobu Takeuchi, Norimitsu Wakao, Masahiro Aoyama, Kazuhiro Hongo, Masakazu Takayasu
BACKGROUND: Various complications after C1 lateral mass and C2 pedicle screw fusion surgery (C1LM-C2PSFS) have been reported. However, to our knowledge, this is the first report of contusional cerebellar hemorrhage caused by placement in the protrusion (chin-out) position after C1LM-2PSFS. CASE DESCRIPTION: An 81-year-old woman complaining of gait disturbance and clumsiness of both hands was diagnosed with cervical myelopathy with atlantoaxial subluxation. After we performed C1LM-C2PSFS, her neurologic deficits gradually improved, and there was no radiologic evidence of construct failure...
May 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28531879/scaffold-requirements-for-periodontal-regeneration-with-enamel-matrix-derivative-proteins
#3
Alessandra Apicella, Peggy Heunemann, Laurent Dejace, Matteo Marascio, Christopher J G Plummer, Peter Fischer
Periodontitis affects the attachment of natural teeth, and infection or inflammation associated with periodontitis may affect peri-implant tissues. Enamel matrix derivative (EMD) proteins provide stimulation for self-regeneration of the damaged tissue when applied to wide intrabony defects as part of a mixture with bone graft material. As a first step of the process enhancing cell proliferation and ligament formation, we demonstrated that EMD protein precipitation depends strongly on the physical and chemical characteristics of the bone grafts used in the mixture...
May 9, 2017: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/28531785/the-relationship-between-malnutrition-risk-and-clinical-outcomes-in-a-cohort-of-frail-older-hospital-patients
#4
Adrian Slee, Deborah Birch, David Stokoe
BACKGROUND & AIMS: Malnutrition has an adverse effect on clinical outcomes and frail older people may be at greater risk of malnutrition. The purpose and aims of this study was to investigate the relationship between markers of malnutrition risk and clinical outcomes in a cohort of frail older hospital patients. METHODS: 78 frail older hospital patients had the following measurements recorded; length of stay (LOS), time to medical fitness for discharge (TMFFD), body mass index (BMI), malnutrition universal screening tool (MUST) and mini-nutritional assessment short-form (MNA-SF) scores, blood urea, C-reactive protein (CRP), albumin, CRP-albumin ratio; and bioelectrical impedance assessment (BIA) measurements (n = 66)...
October 2016: Clinical Nutrition ESPEN
https://www.readbyqxmd.com/read/28531652/lessons-learned-using-a-values-engaged-approach-to-attend-to-culture-diversity-and-equity-in-a-stem-program-evaluation
#5
Ayesha S Boyce
Evaluation must attend meaningfully and respectfully to issues of culture, race, diversity, power, and equity. This attention is especially critical within the evaluation of science, technology, engineering, and mathematics (STEM) educational programming, which has an explicit agenda of broadening participation. The purpose of this article is to report lessons learned from the implementation of a values-engaged, educative (Greene et al., 2006) evaluation within a multi-year STEM education program setting. This meta-evaluation employed a case study design using data from evaluator weekly systematic reflections, review of evaluation and program artifacts, stakeholder interviews, and peer review and assessment...
May 13, 2017: Evaluation and Program Planning
https://www.readbyqxmd.com/read/28531550/barriers-and-facilitators-in-providing-oral-care-to-nursing-home-residents-from-the-perspective-of-care-aides-a-systematic-review-and-meta-analysis
#6
REVIEW
Matthias Hoben, Alix Clarke, Kha Tu Huynh, Nadia Kobagi, Angelle Kent, Huimin Hu, Raissa A C Pereira, Tianyuan Xiong, Kexin Yu, Hongjin Xiang, Minn N Yoon
BACKGROUND: Oral health of nursing home residents is generally poor, with severe consequences for residents' general health and quality of life and for the health care system. Care aides in nursing homes provide up to 80% of direct care (including oral care) to residents, but providing oral care is often challenging. Interventions to improve oral care must tailor to identified barriers and facilitators to be effective. This review identifies and synthesizes the evidence on barriers and facilitators care aides perceive in providing oral care to nursing home residents...
May 11, 2017: International Journal of Nursing Studies
https://www.readbyqxmd.com/read/28531225/protein-charge-distribution-in-proteomes-and-its-impact-on-translation
#7
Rodrigo D Requião, Luiza Fernandes, Henrique José Araujo de Souza, Silvana Rossetto, Tatiana Domitrovic, Fernando L Palhano
As proteins are synthesized, the nascent polypeptide must pass through a negatively charged exit tunnel. During this stage, positively charged stretches can interact with the ribosome walls and slow the translation. Therefore, charged polypeptides may be important factors that affect protein expression. To determine the frequency and distribution of positively and negatively charged stretches in different proteomes, the net charge was calculated for every 30 consecutive amino acid residues, which corresponds to the length of the ribosome exit tunnel...
May 22, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28531214/suspected-lynch-syndrome-associated-msh6-variants-a-functional-assay-to-determine-their-pathogenicity
#8
Hellen Houlleberghs, Anne Goverde, Jarnick Lusseveld, Marleen Dekker, Marco J Bruno, Fred H Menko, Arjen R Mensenkamp, Manon C W Spaander, Anja Wagner, Robert M W Hofstra, Hein Te Riele
Lynch syndrome (LS) is a hereditary cancer predisposition caused by inactivating mutations in DNA mismatch repair (MMR) genes. Mutations in the MSH6 DNA MMR gene account for approximately 18% of LS cases. Many LS-associated sequence variants are nonsense and frameshift mutations that clearly abrogate MMR activity. However, missense mutations whose functional implications are unclear are also frequently seen in suspected-LS patients. To conclusively diagnose LS and enroll patients in appropriate surveillance programs to reduce morbidity as well as mortality, the functional consequences of these variants of uncertain clinical significance (VUS) must be defined...
May 22, 2017: PLoS Genetics
https://www.readbyqxmd.com/read/28531187/multi-scale-computational-study-of-the-mechanical-regulation-of-cell-mitotic-rounding-in-epithelia
#9
Ali Nematbakhsh, Wenzhao Sun, Pavel A Brodskiy, Aboutaleb Amiri, Cody Narciso, Zhiliang Xu, Jeremiah J Zartman, Mark Alber
Mitotic rounding during cell division is critical for preventing daughter cells from inheriting an abnormal number of chromosomes, a condition that occurs frequently in cancer cells. Cells must significantly expand their apical area and transition from a polygonal to circular apical shape to achieve robust mitotic rounding in epithelial tissues, which is where most cancers initiate. However, how cells mechanically regulate robust mitotic rounding within packed tissues is unknown. Here, we analyze mitotic rounding using a newly developed multi-scale subcellular element computational model that is calibrated using experimental data...
May 22, 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28530863/our-work-must-catch-up-to-technology
#10
Tim Gee
No abstract text is available yet for this article.
May 2017: Biomedical Instrumentation & Technology
https://www.readbyqxmd.com/read/28530768/perioperative-management-of-rheumatoid-medications-in-orthopedic-surgery
#11
Kunal Sindhu, Brian Cohen, Joseph A Gil
Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disorder known to cause progressive joint destruction. Over time, untreated RA can lead to pain and increasing disability, making orthopedic intervention necessary. The treatment of RA revolves around a variety of medications that blunt the overall immune response. However, this may increase the risk of infection and impair wound healing. Given the nature of this disease, orthopedists frequently encounter patients with RA in the operative setting. To optimize surgical outcomes, orthopedists must carefully manage and pay special attention to the adverse side effects of the complicated medication regimens of these patients perioperatively...
May 20, 2017: Orthopedics
https://www.readbyqxmd.com/read/28530767/diagnostic-evaluation-of-upper-extremity-masses-and-tumors
#12
Andrew R Tyser, Patrick A Holt, R Lor Randall
The appropriate evaluation of hand and upper extremity masses is an important aspect of the care of orthopedic patients. Although most of these masses are benign, the orthopedic surgeon must have a high index of suspicion when assessing them because early diagnosis and treatment of aggressive or malignant masses may have a great effect on patient outcomes. This article provides an overview of benign and malignant osseous and soft tissue masses that orthopedic surgeons may encounter and a detailed algorithm for evaluating these masses...
May 20, 2017: Orthopedics
https://www.readbyqxmd.com/read/28530622/-laparoscopic-uretero-ureterostomy-for-iatrogenic-lesions-of-the-distal-ur%C3%A3-ter
#13
Álvaro Juárez Soto, Rubén Campanario Pérez, Rocío Sáiz Marenco, Javier Amores Bermúdez, Manuel Soto Delgado, Jose Miguel Arroyo Maestre, Margarita De Paz Suárez
The most frequent ureteral lesions are iatrogenic, mainly due to gynecologic and urologic procedures. The resolution and repair of these lesions, when they require surgery, is often the performance of ureteroneocystostomy. We describe the technique for the repair of distal ureter lesions that preserves both anatomy and function of the urinary tract (1). The operation consists in dissection and extraction of the distal ureteral stump from its intramural tract to get at least 1 cm of free ureter, percutaneous insertion of a ureteral stent, checking the absence of tension between proximal ureter and distal dissected stump, end to end anastomosis and reinsertion of the distal ureter in the previously dissected bladder muscle layer...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530618/robotic-colposacropexy
#14
Miguel Angel Ruiz-León, Lorena Fernández-Montarroso, Natalia Pérez-Romero, Isabel Galante-Romo, Luis Eduardo Resel-Folkersma, Jesús Moreno-Sierra
OBJECTIVES: To review the role of robot- assisted laparoscopic colposacropexy (RALCS) as a treatment for pelvic organ prolapse (POP) accordingly with the available literature and our own experience. METHODS: We have analyzed the studies with the results of robot-assisted colposacropexy (RALCS) and others in which this technique is compared with the abdominal (ACS) and/or the laparoscopic approach (LCS), including our own series. The main data collected are surgical time, blood loss, complications, clinical outcomes, quality of life and the different costs of LCS versus RALCS...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530617/-principles-of-urinary-tract-reconstructive-surgery
#15
Juan Gomez Rivas, Jesús Cisneros Ledo
INTRODUCTION: In the last 15 years, the role of laparoscopic surgery has progressively increased to include reconstructive procedures such as pyeloplasty and management of ureteral stricture, in addition to being a field in continuous development, this refers to the improvement of ergonomics, new instruments and new techniques. We present a review on basic features of laparoscopic reconstructive surgery in urology. ACQUISITION OF EVIDENCE: For this review, an exhaustive literature search was performed in PUBMED, MEDILNE, BioMed central and others, with the keywords: reconstructive surgery, urology, laparoscopy...
May 2017: Archivos Españoles de Urología
https://www.readbyqxmd.com/read/28530536/leuprolide-acetate-release-study-from-%C3%AE-irradiated-plga-based-in-situ-forming-system
#16
Mona Shapourgan, Hamid Mobedi, Nasrin Sheikh, Aliasghar Behnamghader, Arezou Mashak
It is well known that the properties of polymers can be altered by exposure to γ- ray. γ-irradiation has been used as a sterilization method for biodegradable polymeric drug delivery devices, and its drug release profile must not be significantly changed. In this study, the effect of γ-irradiation with 8 kGy doses on the release profile of leuprolide acetate from PLGA-based in situ forming system was evaluated. PLGA-based in situ forming systems were prepared by injecting some specific amount of irradiated solution of PLGA /NMP containing drug into a buffer phosphate pH 7...
March 28, 2017: Current Drug Delivery
https://www.readbyqxmd.com/read/28530453/two-case-studies-illustrating-a-shared-decision-making-approach-to-illicit-methamphetamine-use-and-breastfeeding
#17
Julie Blandthorn, Katie James, Ellen Bowman, Yvonne Bonomo, Lisa H Amir
Crystal methamphetamine (MA) is a potent psycho-stimulant that is increasingly used worldwide. It is highly addictive, is often made in clandestine laboratories, and can cause serious health issues in adults. Health professionals caring for women in the perinatal period must counsel women about the health risks to infants if they are exposed to MA in breast milk. Most guidelines recommend that women who have current or recent MA use do not breastfeed. This article explores approaches to breastfeeding advice in the context of MA use...
May 22, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28530428/short-term-memory-and-long-term-memory-are-still-different
#18
Dennis Norris
A commonly expressed view is that short-term memory (STM) is nothing more than activated long-term memory. If true, this would overturn a central tenet of cognitive psychology-the idea that there are functionally and neurobiologically distinct short- and long-term stores. Here I present an updated case for a separation between short- and long-term stores, focusing on the computational demands placed on any STM system. STM must support memory for previously unencountered information, the storage of multiple tokens of the same type, and variable binding...
May 22, 2017: Psychological Bulletin
https://www.readbyqxmd.com/read/28530406/comparative-evaluation-of-small-molecular-additives-and-their-effects-on-peptide-protein-identification
#19
Jing Gao, Shaoyun Zhong, Yanting Zhou, Han He, Shuying Peng, Zhenyun Zhu, Xing Liu, Jing Zheng, Bin Xu, Hu Zhou
Detergents and salts are widely used in lysis buffers to enhance protein extraction from biological samples, facilitating in-depth proteomic analysis. However, these detergents and salt additives must be efficiently removed from the digested samples prior to LC-MS/MS analysis to obtain high-quality mass spectra. Although filter-aided sample preparation (FASP), acetone precipitation (AP), followed by in-solution digestion, and strong cation exchange-based centrifugal proteomic reactors (CPRs) are commonly used for proteomic sample processing, little is known about their efficiencies at removing detergents and salt additives...
May 22, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28530231/constraining-climate-sensitivity-and-continental-versus-seafloor-weathering-using-an-inverse-geological-carbon-cycle-model
#20
Joshua Krissansen-Totton, David C Catling
The relative influences of tectonics, continental weathering and seafloor weathering in controlling the geological carbon cycle are unknown. Here we develop a new carbon cycle model that explicitly captures the kinetics of seafloor weathering to investigate carbon fluxes and the evolution of atmospheric CO2 and ocean pH since 100 Myr ago. We compare model outputs to proxy data, and rigorously constrain model parameters using Bayesian inverse methods. Assuming our forward model is an accurate representation of the carbon cycle, to fit proxies the temperature dependence of continental weathering must be weaker than commonly assumed...
May 22, 2017: Nature Communications
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